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https://www.readbyqxmd.com/read/28644743/sarcocystis-jamaicensis-n-sp-from-red-tailed-hawks-buteo-jamaicensis-definitive-host-and-ifn-%C3%AE-gene-knockout-mice-as-experimental-intermediate-host
#1
Shiv Verma, Alexa Rosypal Von Dohlen, J Mowery, D Scott, B Rosenthal, J P Dubey, David Lindsay
Here, we report a new species of Sarcocystis with red-tailed hawk (RTH) as the natural definitive host and IFN-γ gene knockout (KO) mice as an experimental intermediate host in which sarcocysts form in muscle. Two RTHs submitted to the Carolina Raptor Center, Huntersville, North Carolina, were euthanized because they could not be rehabilitated and released. Fully sporulated 12.5 x 9.9 m sized sporocysts were found in intestinal scrapings of both hawks. Sporocysts were orally fed to laboratory-reared outbred Swiss Webster mice (SW) (Mus musculus) and also to KO mice...
June 23, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28644414/benefits-facilitators-barriers-and-strategies-to-improve-pesticide-protective-behaviors-insights-from-farmworkers-in-north-carolina-tobacco-fields
#2
AnnMarie Lee Walton, Catherine E LePrevost, Laura Linnan, Ana Sanchez-Birkhead, Kathi Mooney
Pesticide exposure is associated with deleterious health effects. Prior studies suggest Latino farmworkers perceive little control over their occupational health. Using the Health Belief Model as a theoretical guide, we explored the perceptions of Latino farmworkers working in tobacco in North Carolina (n = 72) about benefits and facilitators of pesticide protective behaviors as well as barriers, and strategies to overcome barriers to their use. Interviews were conducted with participants at farmworker housing during non-work time...
June 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28642249/unc-cancer-center-director-to-lead-nci
#3
(no author information available yet)
President Donald Trump has selected Norman "Ned" Sharpless, MD, director of the University of North Carolina Lineberger Comprehensive Cancer Center, to lead the NCI. The news was met with widespread approval among cancer researchers, who view Sharpless as a strong communicator who can ably represent the needs of the cancer community in the face of proposed funding cuts.
June 22, 2017: Cancer Discovery
https://www.readbyqxmd.com/read/28642182/the-effect-of-morbid-obesity-on-subarachnoid-hemorrhage-prognosis-in-the-united-states
#4
Ross-Jordon S Elliott, Daniel Agustin Godoy, Joel E Michalek, Réza Behrouz, Marwah A Elsehety, Shaheryar Hafeez, Denise Rios, Ali Seifi
BACKGROUND: The association between obesity and non-traumatic subarachnoid hemorrhage (SAH) patient outcome is unclear. AIMS: Determine the impact of morbid obesity (body mass index ≥40 kg/m(2)) on non-traumatic SAH outcomes. METHODS: Using the Nationwide Inpatient Sample, we identified hospitalized, non-traumatic SAH patients diagnosed from 2008 to 2013 and tested the effect of obesity on their mortality and clinical outcomes. Odds ratios were estimated with a mixed effects linear logistic model with adjustment for hospital clustering...
June 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28641912/a-2-year-holistic-health-and-stress-intervention-results-of-an-rct-in-clergy
#5
Rae Jean Proeschold-Bell, Elizabeth L Turner, Gary G Bennett, Jia Yao, Xiang-Fang Li, David E Eagle, Rachel A Meyer, Redford B Williams, Robin Y Swift, H Edgar Moore, Melanie A Kolkin, Carl C Weisner, Katherine M Rugani, Holly J Hough, Virginia P Williams, David C Toole
INTRODUCTION: This study sought to determine the effect of a 2-year, multicomponent health intervention (Spirited Life) targeting metabolic syndrome and stress simultaneously. DESIGN: An RCT using a three-cohort multiple baseline design was conducted in 2010-2014. SETTING/PARTICIPANTS: Participants were United Methodist clergy in North Carolina, U.S., in 2010, invited based on occupational status. Of invited 1,745 clergy, 1,114 consented, provided baseline data, and were randomly assigned to immediate intervention (n=395), 1-year waitlist (n=283), or 2-year waitlist (n=436) cohorts for a 48-month trial duration...
June 13, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28641046/exploring-the-health-needs-of-aging-lgbt-adults-in-the-cape-fear-region-of-north-carolina
#6
Noell L Rowan, Kelsey Beyer
This study explored issues of culturally sensitive health care practice and needs among lesbian, gay, bisexual and transgender aging adults in coastal North Carolina. Survey data from 2013 to 2015 were analyzed using frequencies and logistic regression on concerns with culturally sensitive health needs for the LGBT aging adult population. Results indicated that the largest problem was a history of being verbally harassed (n = 115; 51.57%) and a need for more culturally sensitive health care provisions. A large majority of participants requested an improvement in offering of LGBT specific social activities (n = 149), recreational activities (n = 116), and art and cultural activities (n = 112)...
June 22, 2017: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/28638167/computational-fluid-dynamics-analysis-of-the-venturi-dustiness-tester
#7
Prahit Dubey, Urmila Ghia, Leonid A Turkevich
Dustiness quantifies the propensity of a finely divided solid to be aerosolized by a prescribed mechanical stimulus. Dustiness is relevant wherever powders are mixed, transferred or handled, and is important in the control of hazardous exposures and the prevention of dust explosions and product loss. Limited quantities of active pharmaceutical powders available for testing led to the development (at University of North Carolina) of a Venturi-driven dustiness tester. The powder is turbulently injected at high speed (Re ~ 2 × 10(4)) into a glass chamber; the aerosol is then gently sampled (Re ~ 2 × 10(3)) through two filters located at the top of the chamber; the dustiness index is the ratio of sampled to injected mass of powder...
May 2017: Powder Technology
https://www.readbyqxmd.com/read/28637439/a-qualitative-analysis-of-smokers-perceptions-about-lung-cancer-screening
#8
Lindsay Gressard, Amy S DeGroff, Thomas B Richards, Stephanie Melillo, Julia Kish-Doto, Christina L Heminger, Elizabeth A Rohan, Kristine Gabuten Allen
BACKGROUND: In 2013, the US Preventive Services Task Force (USPSTF) began recommending lung cancer screening for high risk smokers aged 55-80 years using low-dose computed tomography (CT) scan. In light of these updated recommendations, there is a need to understand smokers' knowledge of and experiences with lung cancer screening in order to inform the design of patient education and tobacco cessation programs. The purpose of this study is to describe results of a qualitative study examining smokers' perceptions around lung cancer screening tests...
June 21, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28637322/predicting-perceived-isolation-among-midlife-and-older-lgbt-adults-the-role-of-welcoming-aging-service-providers
#9
Jie Yang, Yoosun Chu, Mary Anne Salmon
Background and Objectives: Older lesbian, gay, bisexual, and transgender (LGBT) adults are more likely to live alone and less likely to have children compared with their heterosexual counterparts. The lack of immediate family system can render older LGBT adults particularly vulnerable to social isolation and its consequences. The current study utilizes social exclusion theory, which asserts that not only material resources but also engagement with and inclusion into the society are necessary for marginalized people to be integrated into the mainstream...
June 16, 2017: Gerontologist
https://www.readbyqxmd.com/read/28635424/genome-wide-linkage-and-haplotype-sharing-analysis-implicates-the-mcdr3-locus-as-a-candidate-region-for-a-developmental-macular-disorder-in-association-with-digit-abnormalities
#10
Valentina Cipriani, Ambreen Kalhoro, Gavin Arno, Raquel S Silva, Nikolas Pontikos, Virginie Puech, Michelle E McClements, David M Hunt, Veronica van Heyningen, Michel Michaelides, Andrew R Webster, Anthony T Moore, Bernard Puech
BACKGROUND: Developmental macular disorders are a heterogeneous group of rare retinal conditions that can cause significant visual impairment from childhood. Among these disorders, autosomal dominant North Carolina macular dystrophy (NCMD) has been mapped to 6q16 (MCDR1) with recent support for a non-coding disease mechanism of PRDM13. A second locus on 5p15-5p13 (MCDR3) has been implicated in a similar phenotype, but the disease-causing mechanism still remains unknown. METHODS: Two families affected by a dominant developmental macular disorder that closely resembles NCMD in association with digit abnormalities were included in the study...
March 2, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28633063/serum-perfluoroalkyl-acids-pfaas-and-associations-with-behavioral-attributes
#11
Rebecca Siebenaler, Rochelle Cameron, Craig M Butt, Kate Hoffman, Christopher P Higgins, Heather M Stapleton
The ubiquitous use of poly- and perfluoroalkyl substances (PFASs) in a variety of industrial and consumer products has resulted in chronic exposure in most industrialized nations, and led to measurable concentrations in blood and other tissues in humans across all life stages; however, behavioral attributes that relate to exposure are not well studied. To further investigate how behavior may relate to PFAS exposure, 37 adults were recruited from central North Carolina. Participants provided blood samples and behavioral questionnaires were administered, asking questions about a variety of household, dietary, and behavioral outcomes...
June 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28632539/epidemiologic-analysis-of-elective-operative-procedures-in-infants-less-than-6-months-of-age-in-the-united-states
#12
Lisa M Einhorn, Brian J Young, Jonathan C Routh, Alexander C Allori, Elisabeth T Tracy, Nathaniel H Greene
BACKGROUND: This study uses publicly available data to analyze the total number of elective, potentially deferrable operative procedures involving infants <6 months of age in the United States. We investigated the factors associated with the performance of these procedures in this population. METHODS: The State Ambulatory Surgery Database was used to identify patients in California, North Carolina, New York, and Utah during the years of 2007 to 2010 who were younger than 6 months of age at the time that they underwent outpatient (ambulatory) surgery...
June 16, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28632248/perceived-benefits-and-barriers-to-exercise-for-recently-treated-adults-with-acute-leukemia
#13
Ashley Leak Bryant, AnnMarie L Walton, Mackenzi Pergolotti, Brett Phillips, Charlotte Bailey, Deborah K Mayer, Claudio Battaglini
PURPOSE/OBJECTIVES: To explore perceived exercise benefits and barriers in adults with acute leukemia who recently completed an inpatient exercise intervention during induction therapy.
. RESEARCH APPROACH: Descriptive, exploratory design using semistructured interviews.
. SETTING: Inpatient hematology/oncology unit at North Carolina Cancer Hospital in Chapel Hill.
. PARTICIPANTS: 6 adults with acute leukemia aged 35-67 years...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632036/predictability-and-interpretability-of-hybrid-link-level-crash-frequency-models-for-urban-arterials-compared-to-cluster-based-and-general-negative-binomial-regression-models
#14
Pooya Najaf, Venkata R Duddu, Srinivas S Pulugurtha
Machine learning (ML) techniques have higher prediction accuracy compared to conventional statistical methods for crash frequency modelling. However, their black-box nature limits the interpretability. The objective of this research is to combine both ML and statistical methods to develop hybrid link-level crash frequency models with high predictability and interpretability. For this purpose, M5' model trees method (M5') is introduced and applied to classify the crash data and then calibrate a model for each homogenous class...
February 24, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28627098/effect-of-concomitant-birth-defects-and-genetic-anomalies-on-infant-mortality-in-tetralogy-of-fallot
#15
Eric G Jernigan, Paula D Strassle, Rebecca C Stebbins, Robert E Meyer, Jennifer S Nelson
BACKGROUND: A substantial proportion of infants born with tetralogy of Fallot (TOF) die in infancy. A better understanding of the heterogeneity associated with TOF, including extracardiac malformations and chromosomal anomalies is vital to stratifying risk and optimizing outcomes during infancy. METHODS: Using the North Carolina Birth Defects Monitoring Program, infants diagnosed with TOF and born between 2003 and 2012 were included. Kaplan-Meier survival curves were used to estimate cumulative 1-year mortality, stratified by the presence of concomitant birth defects (BDs) and chromosomal anomalies...
June 19, 2017: Birth defects research
https://www.readbyqxmd.com/read/28626360/delays-and-disabilities-np-screening-and-care-management
#16
Shannon H Ford, Hyunkyung Choi, Susan Brunssen, Marcia Van Riper
Neurodevelopmental Disorders (ND) impair functioning and are associated with increased physical and psychological health risks. ND care is increasingly being provided by NPs in primary care settings. To assess NP's knowledge and care management practices for pediatric patients with potential or existing ND, practicing NPs in North Carolina were invited to complete an online survey. NC NP's provide care to ND patients in a variety of settings and have varied levels of experience with ND. Differences in knowledge, screening, and management practices are identified...
February 2017: Journal for Nurse Practitioners: JNP
https://www.readbyqxmd.com/read/28626298/stress-and-coping-latino-youth-coming-of-age-in-a-new-latino-destination
#17
Maria Brietzke, Krista Perreira
Previous research has linked stress to adverse mental health outcomes among Latino adolescents living in the United States. The mechanism through which this process operates continues to be explored, especially in regions of the country where Latin American immigrants and their children have only recently begun to migrate. Our study aimed to contextualize the processes of stress and coping among Latino adolescents growing up in an emerging Latino destination in the US-North Carolina (NC). All adolescents in our study were either the first or second generation children of immigrants from Latin American countries including Colombia, El Salvador, Honduras, and Mexico...
July 2017: Journal of Adolescent Research
https://www.readbyqxmd.com/read/28626266/deterring-rearrests-for-drinking-and-driving
#18
Frank Sloan, Lindsey Eldred, Sabrina McCutchan, Alyssa Platt
This study assesses why some individuals are re-arrested for driving while intoxicated (DWI). Using longitudinal data from North Carolina containing information on arrests and arrest outcomes, we test hypotheses that individuals prosecuted and convicted of DWI are less likely to be re-arrested for DWI. We allow for possible endogeneity of prosecution and conviction outcomes by using instrumental variables for the prosecutor's prosecution rate and the judge's conviction rate. With a three-year follow-up, the probability of DWI re-arrest was reduced by 6...
October 2016: Southern Economic Journal
https://www.readbyqxmd.com/read/28624727/the-biogeochemical-implications-of-massive-gull-flocks-at-landfills
#19
R Scott Winton, Mark River
Gulls have long been observed concentrating in flocks of tens to hundreds of thousands at the anthropogenic food sources provided by landfills. Yet, the biogeochemical implications of the landfill gull phenomenon have been largely ignored. This study has two goals: 1) to understand the magnitude and geographic extent of landfill gulls in North America, and 2) to quantify the amount of carbon (C), nitrogen (N), and phosphorus (P) transported from landfills to gull roosting sites in order to understand their potential impacts on water quality and methane (CH4) emission...
June 8, 2017: Water Research
https://www.readbyqxmd.com/read/28622109/farmworker-and-non-farmworker-latino-immigrant-men-in-north-carolina-have-high-levels-of-specific-pesticide-urinary-metabolites
#20
Thomas A Arcury, Haiying Chen, Paul J Laurienti, Timothy D Howard, Dana Boyd Barr, Dana C Mora, Sara A Quandt
This paper compares detections and concentrations of specific organophosphate, bis-dithiocarbamate, and pyrethroid insecticide urinary metabolites among Latino male farmworkers and non-farmworkers in North Carolina. Data are from interviews and urine samples collected in 2012 and 2013. Farmworkers and non-farmworkers frequently had detections for OP and pyrethroid pesticide urinary metabolites. Detections of bis-dithiocarbamate urinary metabolites were less frequent, but substantial among the non-farmworkers...
June 16, 2017: Archives of Environmental & Occupational Health
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