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https://www.readbyqxmd.com/read/29347864/dense-breast-notification-laws-impact-on-downstream-imaging-after-screening-mammography
#1
Michal Horný, Alan B Cohen, Richard Duszak, Cindy L Christiansen, Michael Shwartz, James F Burgess
Dense breast tissue is a common finding that decreases the sensitivity of mammography in detecting cancer. Many states have recently enacted dense breast notification (DBN) laws to provide patients with information to help them make better-informed decisions about their health. To test whether DBN legislation affected the probability of screening mammography follow-up by ultrasound and magnetic resonance imaging (MRI), we examined the proportion of times screening mammography was followed by ultrasound or MRI for a series of months pre- and post-legislation...
January 1, 2018: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29342309/prognostic-power-of-a-tumor-differentiation-gene-signature-for-bladder-urothelial-carcinomas
#2
Qianxing Mo, Fotis Nikolos, Fengju Chen, Zoe Tramel, Yu-Cheng Lee, Kazukuni Hayashi, Jing Xiao, Jianjun Shen, Keith Syson Chan
Background: Muscle-invasive bladder cancers (MIBCs) cause approximately 150 000 deaths per year worldwide. Survival for MIBC patients is heterogeneous, with no clinically validated molecular markers that predict clinical outcome. Non-MIBCs (NMIBCs) generally have favorable outcome; however, a portion progress to MIBC. Hence, development of a prognostic tool that can guide decision-making is crucial for improving clinical management of bladder urothelial carcinomas. Methods: Tumor grade is defined by pathologic evaluation of tumor cell differentiation, and it often associates with clinical outcome...
January 12, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29338703/diagnostic-accuracy-and-prediction-increment-of-markers-of-epithelial-mesenchymal-transition-to-assess-cancer-cell-detachment-from-primary-tumors
#3
Evan L Busch, Prabhani Kuruppumullage Don, Haitao Chu, David B Richardson, Temitope O Keku, David A Eberhard, Christy L Avery, Robert S Sandler
BACKGROUND: Metastases play a role in about 90% of cancer deaths. Markers of epithelial-mesenchymal transition (EMT) measured in primary tumor cancer cells might provide diagnostic information about the likelihood that cancer cells have detached from the primary tumor. Used together with established diagnostic tests of detachment-lymph node evaluation and radiologic imaging-EMT marker measurements might improve the ability of clinicians to assess the patient's risk of metastatic disease...
January 16, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29337846/25-hydroxyvitamin-d-and-long-menstrual-cycles-in-a-prospective-cohort-study
#4
Anne Marie Z Jukic, Allen J Wilcox, D Robert McConnaughey, Clarice R Weinberg, Anne Z Steiner
BACKGROUND: Vitamin D insufficiency is associated with subfertility and prolonged estrus cycles in animals, but humans have not been well studied. METHODS: A prospective time-to-pregnancy study, Time to Conceive (2010-2015), collected up to 4 months of daily diary data. Participants were healthy, late reproductive-aged women in North Carolina who were attempting pregnancy. We examined menstrual cycle length as a continuous variable, as well as in categories: long (35+ days) and short (≤25 days)...
January 15, 2018: Epidemiology
https://www.readbyqxmd.com/read/29335049/dental-treatment-and-expenditures-under-general-anesthesia-among-medicaid-enrolled-children-in-north-carolina
#5
Beau D Meyer, Jessica Y Lee, Mark W Casey
PURPOSE: Many studies reporting dental utilization under general anesthesia (GA) are dated. The purpose of this study was to provide contemporaneous data about children receiving dental GA by: (1) determining trends in utilization and associated expenditures; and (2) examining the effects of provider distribution. METHODS: This time series cross-sectional study of Medicaid-eligible children ages zero to eight years old in North Carolina used aggregate Medicaid claims from State Fiscal Years (SFY) 2011 to 2015 to collect demographic and dental treatment information...
November 1, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29333346/boundaries-in-ground-beetle-coleoptera-carabidae-and-environmental-variables-at-the-edges-of-forest-patches-with-residential-developments
#6
Doreen E Davis, Sara A Gagné
Background: Few studies of edge effects on wildlife objectively identify habitat edges or explore non-linear responses. In this paper, we build on ground beetle (Coleoptera: Carabidae) research that has begun to address these domains by using triangulation wombling to identify boundaries in beetle community structure and composition at the edges of forest patches with residential developments. We hypothesized that edges are characterized by boundaries in environmental variables that correspond to marked discontinuities in vegetation structure between maintained yards and forest...
2018: PeerJ
https://www.readbyqxmd.com/read/29332986/fadttster-accelerating-hypothesis-testing-with-functional-analysis-of-diffusion-tensor-tract-statistics
#7
Jean Noel, Juan C Prieto, Martin Styner
Functional Analysis of Diffusion Tensor Tract Statistics (FADTTS) is a toolbox for analysis of white matter (WM) fiber tracts. It allows associating diffusion properties along major WM bundles with a set of covariates of interest, such as age, diagnostic status and gender, and the structure of the variability of these WM tract properties. However, to use this toolbox, a user must have an intermediate knowledge in scripting languages (MATLAB). FADTTSter was created to overcome this issue and make the statistical analysis accessible to any non-technical researcher...
March 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/29325854/considerations-in-the-diagnosis-of-oral-hairy-leukoplakia-an-institutional-experience
#8
Andres Flores-Hidalgo, Si On Lim, Alice E Curran, Ricardo J Padilla, Valerie Murrah
OBJECTIVE: We report here the 10-year experience with oral hairy leukoplakia (OHL) at the Division of Oral and Maxillofacial Pathology at the University of North Carolina at Chapel Hill, NC, USA. STUDY DESIGN: All the associated hematoxylin and eosin and Epstein-Barr virus encoding region in situ hybridization slides of OHL cases between January 1, 2008, and February 1, 2017, were retrieved and reviewed. Collected demographic characteristics, clinical presentation, medical and social histories were reviewed and reported...
November 15, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29325519/providers-preferences-for-pediatric-oral-health-information-in-the-electronic-health-record-a-cross-sectional-survey
#9
Christopher M Shea, Kea Turner, B Alex White, Ye Zhu, R Gary Rozier
BACKGROUND: The majority of primary care physicians support integration of children's oral health promotion and disease prevention into their practices but can experience challenges integrating oral health services into their workflow. Most electronic health records (EHRs) in primary care settings do not include oral health information for pediatric patients. Therefore, it is important to understand providers' preferences for oral health information within the EHR. The objectives of this study are to assess (1) the relative importance of various elements of pediatric oral health information for primary care providers to have in the EHR and (2) the extent to which practice and provider characteristics are associated with these information preferences...
January 11, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29324772/examination-of-clock-and-adcyap1-gene-variation-in-a-neotropical-migratory-passerine
#10
Andrea Contina, Eli S Bridge, Jeremy D Ross, J Ryan Shipley, Jeffrey F Kelly
Complex behavioral traits, such as those making up a migratory phenotype, are regulated by multiple environmental factors and multiple genes. We investigated possible relationships between microsatellite variation at two candidate genes implicated in the control of migratory behavior, Clock and Adcyap1, and several aspects of migratory life-history and evolutionary divergence in the Painted Bunting (Passerina ciris), a species that shows wide variation in migratory and molting strategies across a disjunct distribution...
2018: PloS One
https://www.readbyqxmd.com/read/29322164/efficacy-of-transdermal-estradiol-and-micronized-progesterone-in-the-prevention-of-depressive-symptoms-in-the-menopause-transition-a-randomized-clinical-trial
#11
Jennifer L Gordon, David R Rubinow, Tory A Eisenlohr-Moul, Kai Xia, Peter J Schmidt, Susan S Girdler
Importance: The menopause transition and early postmenopausal period are associated with a 2- to 4-fold increased risk for clinically significant depressive symptoms. Although a few studies suggest that hormone therapy can effectively manage existing depression during this time, to our knowledge, there have been no studies testing whether hormone therapy can prevent the onset of perimenopausal and early postmenopausal depressive symptoms. Objective: To examine the efficacy of transdermal estradiol plus intermittent micronized progesterone (TE+IMP) in preventing depressive symptom onset among initially euthymic perimenopausal and early postmenopausal women...
January 10, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29321903/separating-the-effects-of-water-quality-and-urbanization-on-temperate-insectivorous-bats-at-the-landscape-scale
#12
Han Li, Matina Kalcounis-Rueppell
Many local scale studies have shown that bats respond to water quality degradation or urbanization in a species-specific manner. However, few have separated the effects of urbanization versus water quality degradation on bats, in single city or single watershed case studies. Across North Carolina, USA, we used the standardized North American Bat Monitoring Program mobile transect protocol to survey bat activity in 2015 and 2016 at 41 sites. We collected statewide water quality and urban land cover data to disentangle the effects of urbanization and water quality degradation on bats at the landscape scale...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29321892/regional-patterns-of-declining-butternut-juglans-cinerea-l-suggest-site-characteristics-for-restoration
#13
Randall S Morin, Kurt W Gottschalk, Michael E Ostry, Andrew M Liebhold
Butternut trees dying from a canker disease were first reported in southwestern Wisconsin in 1967. Since then, the disease has caused extensive mortality of butternut throughout its North American range. The objectives of this study were to quantify changes in butternut populations and density across its range and identify habitat characteristics of sites where butternut is surviving in order to locate regions for potential butternut restoration. The natural range of butternut (Juglans cinerea L.) extends over a large region of eastern N...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29321008/effects-of-a-culturally-specific-tobacco-cessation-intervention-among-african-american-quitline-enrollees-a-randomized-controlled-trial
#14
Monica Webb Hooper, Kelly Carpenter, Michael Payne, Ken Resnicow
BACKGROUND: African Americans suffer disproportionately from tobacco-related illness and have more difficulty quitting smoking than other racial/ethnic groups. Previous research indicates that African American treatment-seekers are high utilizers of tobacco quitlines, yet cessation rates via quitlines are lower relative to whites. The goal of the present study is to test the effectiveness of adding a culturally specific, video-based, adjunct to standard quitline care. It is hypothesized that the integration of an evidence-based intervention (Pathways to Freedom: Leading the Way to a Smoke-Free Community©; PTF) into quitline services will increase cessation and treatment engagement compared to control conditions, and that effects will be moderated by sociocultural factors (e...
January 10, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29320996/healthy-apple-program-to-support-child-care-centers-to-alter-nutrition-and-physical-activity-practices-and-improve-child-weight-a-cluster-randomized-trial
#15
Jodi D Stookey, Jane Evans, Curtis Chan, Lisa Tao-Lew, Tito Arana, Susan Arthur
BACKGROUND: North Carolina Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) resources improve child body mass index (BMI) when the resources are introduced by nurses to child care providers, and offered with workshops and incentives. In San Francisco, public health and child care agencies partnered to adapt NAP SACC resources into an annual "Healthy Apple" quality improvement program (HAP). METHODS: This cluster randomized controlled trial pilot-tested integration of the HAP with bi-annual public health screenings by nurses...
December 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29319585/which-us-states-pose-the-greatest-threats-to-military-readiness-and-public-health-public-health-policy-implications-for-a-cross-sectional-investigation-of-cardiorespiratory-fitness-body-mass-index-and-injuries-among-us-army-recruits
#16
Daniel B Bornstein, George L Grieve, Morgan N Clennin, Alexander C McLain, Laurie P Whitsel, Michael W Beets, Keith G Hauret, Bruce H Jones, Mark A Sarzynski
OBJECTIVE: Many states in the southern region of the United States are recognized for higher rates of obesity, physical inactivity, and chronic disease. These states are therefore recognized for their disproportionate public health burden. The purpose of this study was to investigate state-level distributions of cardiorespiratory fitness, body mass index (BMI), and injuries among US Army recruits in order to determine whether or not certain states may also pose disproportionate threats to military readiness and national security...
January 9, 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29318451/bringing-the-national-security-agency-into-the-classroom-ethical-reflections-on-academia-intelligence-agency-partnerships
#17
Christopher Kampe, Gwendolynne Reid, Paul Jones, Colleen S, Sean S, Kathleen M Vogel
Academia-intelligence agency collaborations are on the rise for a variety of reasons. These can take many forms, one of which is in the classroom, using students to stand in for intelligence analysts. Classrooms, however, are ethically complex spaces, with students considered vulnerable populations, and become even more complex when layering multiple goals, activities, tools, and stakeholders over those traditionally present. This does not necessarily mean one must shy away from academia-intelligence agency partnerships in classrooms, but that these must be conducted carefully and reflexively...
January 9, 2018: Science and Engineering Ethics
https://www.readbyqxmd.com/read/29317921/baseline-knowledge-of-potential-pet-toxins-a-survey-of-pharmacists
#18
Natalie W Young, Kenneth D Royal, Gigi S Davidson
Background: Consumer expenditures on their family pets are rapidly increasing, part of which can be attributed to prescription and OTC medications. In turn, community pharmacies are seeking and receiving an increased number of prescriptions for animals. Community pharmacists' ability to safely care for animal patients is relatively unexplored. Human medications, their normal dosing and even medication excipients could be lethal in some animal patients. Objective: The overarching objective of this study was to assess pharmacists' baseline knowledge of potential pet poisons...
October 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/29317739/predicting-polycyclic-aromatic-hydrocarbons-using-a-mass-fraction-approach-in-a-geostatistical-framework-across-north-carolina
#19
Jeanette M Reyes, Heidi F Hubbard, Matthew A Stiegel, Joachim D Pleil, Marc L Serre
Currently in the United States there are no regulatory standards for ambient concentrations of polycyclic aromatic hydrocarbons (PAHs), a class of organic compounds with known carcinogenic species. As such, monitoring data are not routinely collected resulting in limited exposure mapping and epidemiologic studies. This work develops the log-mass fraction (LMF) Bayesian maximum entropy (BME) geostatistical prediction method used to predict the concentration of nine particle-bound PAHs across the US state of North Carolina...
January 9, 2018: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29316617/impact-of-smoking-ban-on-passive-smoke-exposure-in-pregnant-non-smokers-in-the-southeastern-united-states
#20
Julia C Schechter, Bernard F Fuemmeler, Cathrine Hoyo, Susan K Murphy, Junfeng Jim Zhang, Scott H Kollins
Prenatal passive smoke exposure raises risk for negative birth outcomes. Legislation regulating public smoking has been shown to impact exposure levels, though fewer studies involving pregnant women have been conducted within the U.S. where bans are inconsistent across regions. This study examined the effect of a ban enacted in the southeastern U.S. on pregnant women's cotinine levels. Additional analyses compared self-reported exposure to cotinine and identified characteristics associated with passive exposure...
January 6, 2018: International Journal of Environmental Research and Public Health
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