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https://www.readbyqxmd.com/read/29781534/lncrna-meg3-repressed-malignant-melanoma-progression-via-inactivating-wnt-signaling-pathway
#1
Peng Li, Ying Gao, Jun Li, Yu Zhou, Jing Yuan, Huiwen Guan, Peng Yao
Accumulating evidence has indicated that MEG3 can serve as a tumor suppressive lncRNA in various tumors. It is aberrantly expressed in multiple cancers. However, the biological roles of MEG3 in melanoma are poorly understood. Therefore, in our study, we concentrated on the biological mechanism of MEG3 in melanoma progression. First, we observed that MEG3 was obviously decreased in melanoma cells including A375, SK-MEL-1, B16, and A2058 cells compared to human epidermal melanocytes HEMa-LP. MEG3 was restored by transfecting LV-MEG3 in to A375 and A2058 cells...
May 21, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29780991/plasmonically-enhanced-electromotive-force-of-narrow-bandgap-pbs-qd-based-photovoltaics
#2
Xiaowei Li, Paul D McNaughter, Paul O'Brien, Hiro Minamimoto, Kei Murakoshi
Electromotive force of photovoltaics is a key to define the output power density of photovoltaics. Multiple exciton generation (MEG) exhibited by semiconductor quantum dots (QDs) has great potential to enhance photovoltaic performance owing to the ability to generate more than one electron-hole pairs when absorbing a single photon. However, even in MEG-based photovoltaics, limitation of modifying the electromotive force exists due to the intrinsic electrochemical potential of the conduction band-edges of QDs...
May 21, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29780315/automatic-processing-of-changes-in-facial-emotions-in-dysphoria-a-magnetoencephalography-study
#3
Qianru Xu, Elisa M Ruohonen, Chaoxiong Ye, Xueqiao Li, Kairi Kreegipuu, Gabor Stefanics, Wenbo Luo, Piia Astikainen
It is not known to what extent the automatic encoding and change detection of peripherally presented facial emotion is altered in dysphoria. The negative bias in automatic face processing in particular has rarely been studied. We used magnetoencephalography (MEG) to record automatic brain responses to happy and sad faces in dysphoric (Beck's Depression Inventory ≥ 13) and control participants. Stimuli were presented in a passive oddball condition, which allowed potential negative bias in dysphoria at different stages of face processing (M100, M170, and M300) and alterations of change detection (visual mismatch negativity, vMMN) to be investigated...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29778061/syntactic-and-semantic-restrictions-on-morphological-recomposition-meg-evidence-from-greek
#4
K Neophytou, C Manouilidou, L Stockall, A Marantz
Complex morphological processing has been extensively studied in the past decades. However, most of this work has either focused on only certain steps involved in this process, or it has been conducted on a few languages, like English. The purpose of the present study is to investigate the spatiotemporal cortical processing profile of the distinct steps previously reported in the literature, from decomposition to re-composition of morphologically complex items, in a relatively understudied language, Greek. Using magnetoencephalography, we confirm the role of the fusiform gyrus in early, form-based morphological decomposition, we relate the syntactic licensing of stem-suffix combinations to the ventral visual processing stream, somewhat independent from lexical access for the stem, and we further elucidate the role of orbitofrontal regions in semantic composition...
May 16, 2018: Brain and Language
https://www.readbyqxmd.com/read/29777825/the-temporal-evolution-of-conceptual-object-representations-revealed-through-models-of-behavior-semantics-and-deep-neural-networks
#5
B B Bankson, M N Hebart, I I A Groen, C I Baker
Visual object representations are commonly thought to emerge rapidly, yet it has remained unclear to what extent early brain responses reflect purely low-level visual features of these objects and how strongly those features contribute to later categorical or conceptual representations. Here, we aimed to estimate a lower temporal bound for the emergence of conceptual representations by defining two criteria that characterize such representations: 1) conceptual object representations should generalize across different exemplars of the same object, and 2) these representations should reflect high-level behavioral judgments...
May 16, 2018: NeuroImage
https://www.readbyqxmd.com/read/29775550/palliative-sedation-with-oral-medicines-in-an-infant-with-generalized-severe-junctional-epidermolysis-bullosa
#6
Keith P Pasichow, Meg Frizzola, Elissa G Miller
Generalized severe junctional epidermolysis bullosa is a rare mechanobullous skin disorder that is uniformly fatal. We present the case of an infant who received palliative pain management and ultimately proportionate palliative sedation. However, because of the extent of the patient's skin disease, we were unable to provide palliative medication through parenteral routes. We discuss the provision of enteral palliative sedation, including the pharmacology, and creative use of medications to achieve sufficient palliation in this difficult and unique situation...
May 18, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29772924/access-to-care-among-children-with-disabilities-enrolled-in-the-masshealth-commonhealth-buy-in-program
#7
Melissa Hirschi, Angela Wangari Walter, Kasey Wilson, Kate Jankovsky, Beth Dworetzky, Meg Comeau, Sara S Bachman
Children with disabilities utilize more health-care services and incur higher costs than other children do. Medicaid Buy-In programs for children with disabilities have the potential to increase access to benefits while reducing out-of-pocket costs for families whose income exceeds Medicaid eligibility. This study sought to understand how parents and caregivers of Massachusetts children with disabilities perceive access to care under CommonHealth, Massachusetts's Medicaid Buy-In program. Parents and caregivers ( n = 615) whose children were enrolled in CommonHealth participated in a survey assessing the impact of the program...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29772288/eating-patterns-and-food-intake-of-persons-with-type-1-diabetes-within-the-t1d-exchange
#8
Margaret A Powers, Robin L Gal, Crystal G Connor, Meg Mangan, David M Maahs, Mark A Clements, Elizabeth J Mayer-Davis
AIMS: To identify dietary intake and eating patterns of people with type 1 diabetes from childhood to later adulthood in relation to HbA1c. METHODS: Trained interviewers conducted 24-hour recalls via phone utilizing a multiple pass approach and administered two nutrition questionnaires; 463 participants (or parents of participants) within the T1D Exchange clinic registry were included. Participants were 5 to 81 years with 80-101 participants in five age groups; 56% were female, and 92% were white, with a median diabetes duration of 11...
May 14, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29768971/integrating-eeg-and-meg-signals-to-improve-motor-imagery-classification-in-brain-computer-interface
#9
Marie-Constance Corsi, Mario Chavez, Denis Schwartz, Laurent Hugueville, Ankit N Khambhati, Danielle S Bassett, Fabrizio De Vico Fallani
We adopted a fusion approach that combines features from simultaneously recorded electroencephalogram (EEG) and magnetoencephalogram (MEG) signals to improve classification performances in motor imagery-based brain-computer interfaces (BCIs). We applied our approach to a group of 15 healthy subjects and found a significant classification performance enhancement as compared to standard single-modality approaches in the alpha and beta bands. Taken together, our findings demonstrate the advantage of considering multimodal approaches as complementary tools for improving the impact of noninvasive BCIs...
April 2, 2018: International Journal of Neural Systems
https://www.readbyqxmd.com/read/29766384/increased-functional-meg-connectivity-as-a-hallmark-of-mri-negative-focal-and-generalized-epilepsy
#10
Yiwen Li Hegner, Justus Marquetand, Adham Elshahabi, Silke Klamer, Holger Lerche, Christoph Braun, Niels K Focke
Epilepsy is one of the most prevalent neurological diseases with a high morbidity. Accumulating evidence has shown that epilepsy is an archetypical neural network disorder. Here we developed a non-invasive cortical functional connectivity analysis based on magnetoencephalography (MEG) to assess commonalities and differences in the network phenotype in different epilepsy syndromes (non-lesional/cryptogenic focal and idiopathic/genetic generalized epilepsy). Thirty-seven epilepsy patients with normal structural brain anatomy underwent a 30-min resting state MEG measurement with eyes closed...
May 15, 2018: Brain Topography
https://www.readbyqxmd.com/read/29765298/real-time-tracking-of-selective-auditory-attention-from-m-eeg-a-bayesian-filtering-approach
#11
Sina Miran, Sahar Akram, Alireza Sheikhattar, Jonathan Z Simon, Tao Zhang, Behtash Babadi
Humans are able to identify and track a target speaker amid a cacophony of acoustic interference, an ability which is often referred to as the cocktail party phenomenon. Results from several decades of studying this phenomenon have culminated in recent years in various promising attempts to decode the attentional state of a listener in a competing-speaker environment from non-invasive neuroimaging recordings such as magnetoencephalography (MEG) and electroencephalography (EEG). To this end, most existing approaches compute correlation-based measures by either regressing the features of each speech stream to the M/EEG channels (the decoding approach) or vice versa (the encoding approach)...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29765297/group-analysis-in-fieldtrip-of-time-frequency-responses-a-pipeline-for-reproducibility-at-every-step-of-processing-going-from-individual-sensor-space-representations-to-an-across-group-source-space-representation
#12
Lau M Andersen
An important aim of an analysis pipeline for magnetoencephalographic (MEG) data is that it allows for the researcher spending maximal effort on making the statistical comparisons that will answer his or her questions. The example question being answered here is whether the so-called beta rebound differs between novel and repeated stimulations. Two analyses are presented: going from individual sensor space representations to, respectively, an across-group sensor space representation and an across-group source space representation...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29762070/developing-a-palliative-care-competency-framework-for-health-professionals-and-volunteers-the-nova-scotian-experience
#13
Meg McCallum, Janet Carver, David Dupere, Sharon Ganong, J David Henderson, Ann McKim, Lisa McNeil-Campbell, Holly Richardson, Judy Simpson, Cheryl Tschupruk, Heather Jewers
BACKGROUND AND OBJECTIVES: In 2014, Nova Scotia released a provincial palliative care strategy and implementation working groups were established. The Capacity Building and Practice Change Working Group, comprised of health professionals, public advisors, academics, educators, and a volunteer supervisor, was asked to select palliative care education programs for health professionals and volunteers. The first step in achieving this mandate was to establish competencies for health professionals and volunteers caring for patients with life-limiting illness and their families and those specializing in palliative care...
May 15, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29755332/neurofeedback-and-the-neural-representation-of-self-lessons-from-awake-state-and-sleep
#14
Andreas A Ioannides
Neurofeedback has been around for half a century, but despite some promising results it is not yet widely appreciated. Recently, some of the concerns about neurofeedback have been addressed with functional magnetic resonance imaging and magnetoencephalography adding their contributions to the long history of neurofeedback with electroencephalography. Attempts to address other concerns related to methodological issues with new experiments and meta-analysis of earlier studies, have opened up new questions about its efficacy...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29755314/non-invasive-investigation-of-human-hippocampal-rhythms-using-magnetoencephalography-a-review
#15
REVIEW
Yi Pu, Douglas O Cheyne, Brian R Cornwell, Blake W Johnson
Hippocampal rhythms are believed to support crucial cognitive processes including memory, navigation, and language. Due to the location of the hippocampus deep in the brain, studying hippocampal rhythms using non-invasive magnetoencephalography (MEG) recordings has generally been assumed to be methodologically challenging. However, with the advent of whole-head MEG systems in the 1990s and development of advanced source localization techniques, simulation and empirical studies have provided evidence that human hippocampal signals can be sensed by MEG and reliably reconstructed by source localization algorithms...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29750710/insufficient-and-scant-endometrial-samples-determining-clinicopathologic-outcomes-and-consistency-in-reporting
#16
Emily A Goebel, C Meg McLachlin, Helen C Ettler, Michele M Weir
There are no widely accepted pathologic criteria for reporting endometrial samples with limited tissue and no consensus on the clinical follow-up of patients with these samples. Our study compares clinicopathologic outcomes and determines reporting consistency for these samples. This was done in 3 parts: (1) retrospective chart review of all patients with reported insufficient or scant endometrial samples from 2010 to 2013 at our center to determine repeat sampling and final pathologic diagnosis; (2) survey of gynecologists about their practice for managing patients with these samples; (3) blind review of 99 cases of previously reported scant or insufficient samples in which 4 reviewers separately reassigned cases as scant, insufficient, or diagnostic...
May 10, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29749002/school-level-practices-and-perceptions-associated-with-salad-bars-in-schools
#17
Meg Bruening, Marc A Adams, Punam Ohri-Vachaspati, Jane Hurley
BACKGROUND: Salad bars are placed in schools to promote fruit and vegetable consumption among students. This study assessed differences in school nutrition practices and perceptions in schools with and without salad bars. METHODS: Cross-sectional surveys were completed by school nutrition managers (N = 648) in Arizona schools participating in the National School Lunch Program during 2013-2014. Mixed general estimating equation binomial regressions assessed factors related to having a salad bar after mutually adjusting for clustering within districts, school level, free/reduced rate, and respondents' time in current position...
June 2018: Journal of School Health
https://www.readbyqxmd.com/read/29746907/oscillatory-networks-of-high-level-mental-alignment-a-perspective-taking-meg-study
#18
R A Seymour, H Wang, G Rippon, K Kessler
Mentally imagining another's perspective is a high-level social process, reliant on manipulating internal representations of the self in an embodied manner. Recently Wang et al. (2016) showed that theta-band (3-7Hz) brain oscillations within the right temporo-parietal junction (rTPJ) and brain regions coding for motor/body schema contribute to the process of perspective-taking. Using a similar paradigm, we set out to unravel the extended functional brain network in detail. Increasing the angle between self and other perspective was accompanied by longer reaction times and increases in theta power within rTPJ, right lateral pre-frontal cortex (PFC) and right anterior cingulate cortex (ACC)...
May 7, 2018: NeuroImage
https://www.readbyqxmd.com/read/29746906/multi-subject-hierarchical-inverse-covariance-modelling-improves-estimation-of-functional-brain-networks
#19
Giles L Colclough, Mark W Woolrich, Samuel J Harrison, Pedro A Rojas López, Pedro A Valdes-Sosa, Stephen M Smith
A Bayesian model for sparse, hierarchical inverse covariance estimation is presented, and applied to multi-subject functional connectivity estimation in the human brain. It enables simultaneous inference of the strength of connectivity between brain regions at both subject and population level, and is applicable to fmri, meg and eeg data. Two versions of the model can encourage sparse connectivity, either using continuous priors to suppress irrelevant connections, or using an explicit description of the network structure to estimate the connection probability between each pair of regions...
May 7, 2018: NeuroImage
https://www.readbyqxmd.com/read/29746486/localizing-on-scalp-meg-sensors-using-an-array-of-magnetic-dipole-coils
#20
Christoph Pfeiffer, Lau M Andersen, Daniel Lundqvist, Matti Hämäläinen, Justin F Schneiderman, Robert Oostenveld
Accurate estimation of the neural activity underlying magnetoencephalography (MEG) signals requires co-registration i.e., determination of the position and orientation of the sensors with respect to the head. In modern MEG systems, an array of hundreds of low-Tc SQUID sensors is used to localize a set of small, magnetic dipole-like (head-position indicator, HPI) coils that are attached to the subject's head. With accurate prior knowledge of the positions and orientations of the sensors with respect to one another, the HPI coils can be localized with high precision, and thereby the positions of the sensors in relation to the head...
2018: PloS One
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