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https://www.readbyqxmd.com/read/28921756/temporal-alignment-of-anticipatory-motor-cortical-beta-lateralisation-in-hidden-visual-motor-sequences
#1
Simone G Heideman, Freek van Ede, Anna C Nobre
Performance improves when participants respond to events that are structured in repeating sequences, suggesting that learning can lead to proactive anticipatory preparation. Whereas most sequence-learning studies have emphasized spatial structure, most sequences also contain a prominent temporal structure. We used MEG to investigate spatial and temporal anticipatory neural dynamics in a modified serial reaction-time (SRT) task. Performance and brain activity were compared between blocks with learned spatial-temporal sequences and blocks with new sequences...
September 16, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28920892/computationally-efficient-algorithms-for-sparse-dynamic-solutions-to-the-eeg-source-localization-problem
#2
Elvira Pirondini, Behtash Babadi, Gabriel Obregon-Henao, Camilo Lamus, Wasim Q Malik, Matti S Hamalainen, Patrick L Purdon
OBJECTIVE: Electroencephalography (EEG) and magnetoencephalography (MEG) non-invasively record scalp electromagnetic fields generated by cerebral currents, revealing millisecond-level brain dynamics useful for neuroscience and clinical applications. Estimating the currents that generate these fields, i.e., source localization, is an ill-conditioned inverse problem. Solutions to this problem have focused on spatial continuity constraints, dynamic modeling, or sparsity constraints. The combination of these key ideas could offer significant performance improvements, but substantial computational costs pose a challenge for practical application of such approaches...
September 14, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28919850/the-detection-of-phase-amplitude-coupling-during-sensory-processing
#3
Robert A Seymour, Gina Rippon, Klaus Kessler
There is increasing interest in understanding how the phase and amplitude of distinct neural oscillations might interact to support dynamic communication within the brain. In particular, previous work has demonstrated a coupling between the phase of low frequency oscillations and the amplitude (or power) of high frequency oscillations during certain tasks, termed phase amplitude coupling (PAC). For instance, during visual processing in humans, PAC has been reliably observed between ongoing alpha (8-13 Hz) and gamma-band (>40 Hz) activity...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28917501/personalized-translational-epilepsy-research-novel-approaches-and-future-perspectives-part-i-clinical-and-network-analysis-approaches
#4
REVIEW
Felix Rosenow, Natascha van Alphen, Albert Becker, Andreas Chiocchetti, Ralf Deichmann, Thomas Deller, Thomas Freiman, Christine M Freitag, Johannes Gehrig, Anke M Hermsen, Peter Jedlicka, Christian Kell, Karl Martin Klein, Susanne Knake, Dimitri M Kullmann, Stefan Liebner, Braxton A Norwood, Diana Omigie, Karlheinz Plate, Andreas Reif, Philipp S Reif, Yvonne Reiss, Jochen Roeper, Michael W Ronellenfitsch, Stephanie Schorge, Gerhard Schratt, Stephan W Schwarzacher, Joachim P Steinbach, Adam Strzelczyk, Jochen Triesch, Marlies Wagner, Matthew C Walker, Frederic von Wegner, Sebastian Bauer
Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating brain injury or to reverse established epilepsy have been identified to date. This is likely in part due to the polyetiologic nature of epilepsy, which in turn requires personalized medicine approaches. Recent advances in imaging, pathology, genetics and epigenetics have led to new pathophysiological concepts and the identification of monogenic causes of epilepsy...
September 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28917498/personalized-translational-epilepsy-research-novel-approaches-and-future-perspectives-part-ii-experimental-and-translational-approaches
#5
REVIEW
Sebastian Bauer, Natascha van Alphen, Albert Becker, Andreas Chiocchetti, Ralf Deichmann, Thomas Deller, Thomas Freiman, Christine M Freitag, Johannes Gehrig, Anke M Hermsen, Peter Jedlicka, Christian Kell, Karl Martin Klein, Susanne Knake, Dimitri M Kullmann, Stefan Liebner, Braxton A Norwood, Diana Omigie, Karlheinz Plate, Andreas Reif, Philipp S Reif, Yvonne Reiss, Jochen Roeper, Michael W Ronellenfitsch, Stephanie Schorge, Gerhard Schratt, Stephan W Schwarzacher, Joachim P Steinbach, Adam Strzelczyk, Jochen Triesch, Marlies Wagner, Matthew C Walker, Frederic von Wegner, Felix Rosenow
Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating brain injury or to reverse established epilepsy have been identified to date. This is likely in part due to the polyetiologic nature of epilepsy, which in turn requires personalized medicine approaches. Recent advances in imaging, pathology, genetics, and epigenetics have led to new pathophysiological concepts and the identification of monogenic causes of epilepsy...
September 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28917446/amplitude-modulation-rate-dependent-topographic-organization-of-the-auditory-steady-state-response-in-human-auditory-cortex
#6
Nathan Weisz, Chrysoula Lithari
Periodic modulations of an acoustic feature, such as amplitude over a certain frequency range, leads to phase locking of neural responses to the envelope of the modulation. Using electrophysiological methods this neural activity pattern, also called the auditory steady-state response (aSSR), is visible following frequency transformation of the evoked response as a clear spectral peak at the modulation frequency. Despite several studies employing the aSSR that show, for example, strongest responses for ∼40 Hz and an overall right-hemispheric dominance, it has not been investigated so far to what extent within auditory cortex different modulation frequencies elicit aSSRs at a homogenous source or whether the localization of the aSSR is topographically organized in a systematic manner...
September 11, 2017: Hearing Research
https://www.readbyqxmd.com/read/28917359/dance-is-more-than-therapy-qualitative-analysis-on-therapeutic-dancing-classes-for-parkinson-s
#7
Priscila A Rocha, Susan C Slade, Jodie McClelland, Meg E Morris
OBJECTIVES: To understand the benefits and limitations of therapeutic dancing classes for people with Parkinson's disease (PD) and how best to design and implement classes. DESIGN: A stakeholder forum explored the opinions of 18 allied health clinicians, dance instructors, people with PD and caregivers. Data were thematically analysed and interpreted within a grounded theory framework. RESULTS: Four main themes were identified: (1) the need to consider the stage of disease progression when designing classes; (2) recognition that dance is more than just therapy; (3) the benefits of carefully selecting music to move by; (4) ways to design classes that are both feasible and engaging...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28912698/altered-rich-club-and-frequency-dependent-subnetwork-organization-in-mild-traumatic-brain-injury-a-meg-resting-state-study
#8
Marios Antonakakis, Stavros I Dimitriadis, Michalis Zervakis, Andrew C Papanicolaou, George Zouridakis
Functional brain connectivity networks exhibit "small-world" characteristics and some of these networks follow a "rich-club" organization, whereby a few nodes of high connectivity (hubs) tend to connect more densely among themselves than to nodes of lower connectivity. The Current study followed an "attack strategy" to compare the rich-club and small-world network organization models using Magnetoencephalographic (MEG) recordings from mild traumatic brain injury (mTBI) patients and neurologically healthy controls to identify the topology that describes the underlying intrinsic brain network organization...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28911851/cortisol-awakening-response-in-patients-with-bipolar-disorder-during-acute-episodes-and-partial-remission-a-pilot-study
#9
Ming-Chyi Huang, Shan-Chi Chuang, Mei-Chih Meg Tseng, Yi-Ling Chien, Shih-Cheng Liao, Hsi-Chung Chen, Po-Hsiu Kuo
This exploratory study examined the cortisol awakening response (CAR) in patients with bipolar disorder (BPD) at acute phases and partial remission of manic or depressive episodes. Saliva samples of twenty-seven BPD inpatients and 25 healthy controls were collected to determine the CAR patterns, and 12 patients were sampled again at partial remission. BPD patients exhibited a non-enhanced CAR pattern. Lower cortisol expression and a blunted CAR distinguished bipolar-depressive patients from the controls. The intra-individual follow-up for both patient groups revealed a non-significant improvement in CAR patterns, indicating a trend of a normalized CAR after partial remission for BPD patients...
September 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28905204/racial-vs-self-affirmation-as-a-protective-mechanism-against-the-effects-of-racial-exclusion-on-negative-affect-and-substance-use-vulnerability-among-black-young-adults
#10
Michelle L Stock, Frederick X Gibbons, Janine B Beekman, Kipling D Williams, Laura S Richman, Meg Gerrard
Affirming one's racial identity may help protect against the harmful effects of racial exclusion on substance use cognitions. This study examined whether racial versus self-affirmation (vs. no affirmation) buffers against the effects of racial exclusion on substance use willingness and substance use word associations in Black young adults. It also examined anger as a potential mediator of these effects. After being included, or racially excluded by White peers, participants were assigned to a writing task: self-affirmation, racial-affirmation, or describing their sleep routine (neutral)...
September 13, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28904983/structure-function-relationships-in-the-visual-system-in-multiple-sclerosis-an-meg-and-oct-study
#11
Prejaas Tewarie, Lisanne J Balk, Arjan Hillebrand, Martijn D Steenwijk, Bernard M J Uitdehaag, Cornelis J Stam, Axel Petzold
BACKGROUND: We conducted a multi-modal optical coherence tomography (OCT) and magnetoencephalography (MEG) study to test whether there is a relationship between retinal layer integrity and electrophysiological activity and connectivity (FC) in the visual network influenced by optic neuritis (ON) in patients with multiple sclerosis (MS). METHODS: One hundred and two MS patients were included in this MEG/OCT study. Retinal OCT data were collected from the optic discs, macular region, and segmented...
September 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28903785/food-insecurity-and-emotional-health-in-the-usa-a-systematic-narrative-review-of-longitudinal-research
#12
Meg Bruening, Lauren M Dinour, Jose B Rosales Chavez
OBJECTIVE: To examine the causal directionality in the relationship between food insecurity and emotional well-being among US-based populations. DESIGN: Systematic literature review from January 2006 to July 2016 using MEDLINE (PubMed), PsychInfo, Web of Science and CINHAL. Inclusion criteria were: written in English; examined a longitudinal association between food insecurity and emotional well-being. SETTING: The USA. SUBJECTS: Children and adults...
September 14, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28900289/spatiotemporal-brain-dynamics-of-auditory-temporal-assimilation
#13
Naruhito Hironaga, Takako Mitsudo, Mariko Hayamizu, Yoshitaka Nakajima, Hiroshige Takeichi, Shozo Tobimatsu
Time is a fundamental dimension, but millisecond-level judgments sometimes lead to perceptual illusions. We previously introduced a "time-shrinking illusion" using a psychological paradigm that induces auditory temporal assimilation (ATA). In ATA, the duration of two successive intervals (T1 and T2), marked by three auditory stimuli, can be perceived as equal when they are not. Here, we investigate the spatiotemporal profile of human temporal judgments using magnetoencephalography (MEG). Behavioural results showed typical ATA: participants judged T1 and T2 as equal when T2 - T1 ≤ +80 ms...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28900010/prior-expectations-induce-prestimulus-sensory-templates
#14
Peter Kok, Pim Mostert, Floris P de Lange
Perception can be described as a process of inference, integrating bottom-up sensory inputs and top-down expectations. However, it is unclear how this process is neurally implemented. It has been proposed that expectations lead to prestimulus baseline increases in sensory neurons tuned to the expected stimulus, which in turn, affect the processing of subsequent stimuli. Recent fMRI studies have revealed stimulus-specific patterns of activation in sensory cortex as a result of expectation, but this method lacks the temporal resolution necessary to distinguish pre- from poststimulus processes...
September 12, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28898290/comparative-effectiveness-and-tolerance-of-immunosuppressive-treatments-for-idiopathic-membranous-nephropathy-a-network-meta-analysis
#15
Song Ren, Ying Wang, Li Xian, Tadashi Toyama, Meg Jardine, Guisen Li, Vlado Perkovic, Daqing Hong
BACKGROUND: Immunosuppressive agents in general are shown to prevent renal progression and all-cause mortality in idiopathic membranous nephropathy (IMN) patients with nephrotic syndrome. However, the efficacy and safety of different immunosuppressive treatments have not been systematic assessed and compared. A network meta-analysis was performed to compare different immunosuppressive treatment in IMN. METHODS: Cochrane library, MEDLINE, EMBASE and trial register system were searched for randomized controlled trials reporting the treatments for IMN to May 3, 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28898134/the-management-of-complex-pain-in-children-referred-to-a-pain-clinic-at-a-tertiary-children-s-hospital-in-australia
#16
John Collins, Natasha Haynes, Hannah Klingberg, Heather Nicholas, Meg Pounder, Renee Sandells
Synopsis One of the key aspects of good healthcare for children and young people is the prevention and management of pain. The experience of persisting pain in children and adolescents has a major impact not only on the individual's physical, emotional, social, and developmental well-being but it also may have an impact on the broader world which may include family, school, and social networks. The multi-disciplinary paediatric pain clinic adopts a holistic approach to care through a biopsychosocial model. One outcome of an initial paediatric pain clinic review is the creation of a pain management plan which addresses the pharmacological, physical, psychological, and other domains of care...
September 12, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28893608/adaptive-cortical-parcellations-for-source-reconstructed-eeg-meg-connectomes
#17
Seyedeh-Rezvan Farahibozorg, Richard N Henson, Olaf Hauk
There is growing interest in the rich temporal and spectral properties of the brain's functional connectome that are provided by Electro- and Magnetoencephalography (EEG/MEG). However, the problem of leakage between brain sources that arises when reconstructing brain activity from EEG/MEG recordings outside the head makes it difficult to distinguish true connections from spurious connections, even when connections are based on measures that ignore zero-lag dependencies. In particular, standard anatomical parcellations for potential cortical sources tend to over- or under-sample the real spatial resolution of EEG/MEG...
September 8, 2017: NeuroImage
https://www.readbyqxmd.com/read/28891514/cognitive-responses-and-cortical-oscillatory-processing-at-various-stereoscopic-depths%C3%A2-a%C3%A2-simultaneous-eeg-meg-study
#18
Hohyun Cho, Min-Koo Kang, Sangtae Ahn, Moonyoung Kwon, Kuk-Jin Yoon, Kiwoong Kim, Sung Chan Jun
Due to the recent explosion in various forms of 3D content, the evaluation of such content from a neuroscience perspective is quite interesting. However, existing investigations of cortical oscillatory responses in stereoscopic depth perception are quite rare. Therefore, we investigated spatiotemporal and spatio-temporo-spectral features at four different stereoscopic depths within the comfort zone. We adopted a simultaneous EEG/MEG acquisition technique to collect the oscillatory responses of eight participants...
2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28891497/a-framework-to-reconcile-frequency-scaling-measurements-from-intracellular-recordings-local-field-potentials-up-to-eeg-and-meg%C3%A2-signals
#19
Claude Bedard, Jean-Marie Gomes, Thierry Bal, Alain Destexhe
In this viewpoint article, we discuss the electric properties of the medium around neurons, which are important to correctly interpret extracellular potentials or electric field effects in neural tissue. We focus on how these electric properties shape the frequency scaling of brain signals at different scales, such as intracellular recordings, the local field potential (LFP), the electroencephalogram (EEG) or the magnetoencephalogram (MEG). These signals display frequency-scaling properties which are not consistent with resistive media...
2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28891322/data-driven-topological-filtering-based-on-orthogonal-minimal-spanning-trees-application-to-multi-group-meg-resting-state-connectivity
#20
Stavros I Dimitriadis, Marios Antonakakis, Panagiotis Simos, Jack M Fletcher, Andrew C Papanicolaou
In the present study a novel data-driven topological filtering technique is introduced to derive the backbone of functional brain networks relying on orthogonal minimal spanning trees (OMST). The method aims to identify the essential functional connections to ensure optimal information flow via the objective criterion of global efficiency minus the cost of surviving connections. The OMST technique was applied to multichannel, resting-state neuromagnetic recordings from four groups of participants: healthy adults (n=50), adults who have suffered mild traumatic brain injury (n=30), typically developing children (n=27), and reading-disabled children (n=25)...
September 11, 2017: Brain Connectivity
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