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https://www.readbyqxmd.com/read/28334883/selective-impairment-of-hippocampus-and-posterior-hub-areas-in-alzheimer-s-disease-an-meg-based-multiplex-network-study
#1
Meichen Yu, Marjolein M A Engels, Arjan Hillebrand, Elisabeth C W van Straaten, Alida A Gouw, Charlotte Teunissen, Wiesje M van der Flier, Philip Scheltens, Cornelis J Stam
Although frequency-specific network analyses have shown that functional brain networks are altered in patients with Alzheimer's disease, the relationships between these frequency-specific network alterations remain largely unknown. Multiplex network analysis is a novel network approach to study complex systems consisting of subsystems with different types of connectivity patterns. In this study, we used magnetoencephalography to integrate five frequency-band specific brain networks in a multiplex framework...
March 16, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28334214/tdcs-modulates-visual-gamma-oscillations-and-basal-alpha-activity-in-occipital-cortices-evidence-from-meg
#2
Tony W Wilson, Timothy J McDermott, Mackenzie S Mills, Nathan M Coolidge, Elizabeth Heinrichs-Graham
Transcranial direct-current stimulation (tDCS) is now a widely used method for modulating the human brain, but the resulting physiological effects are not understood. Recent studies have combined magnetoencephalography (MEG) with simultaneous tDCS to evaluate online changes in occipital alpha and gamma oscillations, but no study to date has quantified the offline (i.e., after tDCS) alterations in these responses. Thirty-five healthy adults received active or sham anodal tDCS to the occipital cortices, and then completed a visual stimulation paradigm during MEG that is known to elicit robust gamma and alpha oscillations...
March 10, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28333787/building-research-infrastructure-in-magnet%C3%A2-hospitals-current-status-and-future-directions
#3
Meg Johantgen, Marianne Weiss, Vicki Lundmark, Robin Newhouse, Karen Haller, Lynn Unruh, Maria Shirey
OBJECTIVE: The aim of this study was to describe the infrastructures supporting research in Magnet® hospitals. BACKGROUND: Hospitals undertaking the journey toward Magnet designation must build research and evidence-based practice (EBP) infrastructures that support the infusion of research and EBP into clinical practice. METHODS: An electronic survey was developed and distributed to the chief nursing officer or Magnet coordinator of all Magnet hospitals between June 10, 2015, and July 8, 2015...
April 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28331799/commonalities-and-differences-in-the-neural-substrates-of-threat-predictability-in-panic-disorder-and-specific-phobia
#4
Anna Luisa Klahn, Isabelle A Klinkenberg, Ulrike Lueken, Swantje Notzon, Volker Arolt, Christo Pantev, Peter Zwanzger, Markus Junghoefer
Different degrees of threat predictability are thought to induce either phasic fear or sustained anxiety. Maladaptive, sustained anxious apprehension is thought to result in overgeneralization of anxiety and thereby to contribute to the development of anxiety disorders. Therefore, differences in threat predictability have been associated with pathological states of anxiety with specific phobia (SP) representing phasic fear as heightened response to predictable threat, while panic disorder (PD) is characterized by sustained anxiety (unpredictable threat) and, as a consequence, overgeneralization of fear...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28329686/demethylated-hsatii-dna-and-hsatii-rna-foci-sequester-prc1-and-mecp2-into-cancer-specific-nuclear-bodies
#5
Lisa L Hall, Meg Byron, Dawn M Carone, Troy W Whitfield, Gayle P Pouliot, Andrew Fischer, Peter Jones, Jeanne B Lawrence
This study reveals that high-copy satellite II (HSATII) sequences in the human genome can bind and impact distribution of chromatin regulatory proteins and that this goes awry in cancer. In many cancers, master regulatory proteins form two types of cancer-specific nuclear bodies, caused by locus-specific deregulation of HSATII. DNA demethylation at the 1q12 mega-satellite, common in cancer, causes PRC1 aggregation into prominent Cancer-Associated Polycomb (CAP) bodies. These loci remain silent, whereas HSATII loci with reduced PRC1 become derepressed, reflecting imbalanced distribution of UbH2A on these and other PcG-regulated loci...
March 21, 2017: Cell Reports
https://www.readbyqxmd.com/read/28329401/indoor-tanning-initiation-among-tanners-in-the-united-states
#6
Meg Watson, Meredith Shoemaker, Katie Baker
No abstract text is available yet for this article.
March 22, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28329236/impact-of-hiv-drug-resistance-on-hiv-aids-associated-mortality-new-infections-and-antiretroviral-therapy-program-costs-in-sub-saharan-africa
#7
Andrew N Phillips, John Stover, Valentina Cambiano, Fumiyo Nakagawa, Michael R Jordan, Deenan Pillay, Meg Doherty, Paul Revill, Silvia Bertagnolio
To inform the level of attention to be given by antiretroviral therapy (ART) programs to HIV drug resistance (HIVDR), we used an individual-level model to estimate its impact on future AIDS deaths, HIV-incidence and ART program costs in sub-Saharan Africa (SSA) for a range of program situations. We applied this to SSA through the Spectrum-Goals model. In a situation in which current levels of pre-treatment HIVDR are over 10% (mean 15%), 16% of AIDS deaths (890,000 deaths) , 9% of new infections (450,000) and 8% ($6...
February 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28327467/automated-detection-of-epileptic-ripples-in-meg-using-beamformer-based-virtual-sensors
#8
Carolina Migliorelli, Joan Alonso, Sergio Romero, Rafal Nowak, Antonio Russi, Miguel Mananas
OBJECTIVE: In epilepsy, high-frequency oscillations (HFOs) are considered events highly linked to the seizure onset zone (SOZ). The detection of HFOs in noninvasive signals such as scalp EEG and MEG is still a challenging task. The aim of this study was to automatize the detection of ripples in MEG signals reducing the high-frequency noise using beamformer-based virtual sensors (VS) and applying an automatic procedure exploring the time-frequency content of the detected events. APPROACH: 200 seconds of MEG signals and simultaneous iEEG were selected in nine patients with refractory epilepsy...
March 22, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28325177/equine-cardiovascular-therapeutics
#9
REVIEW
Meg M Sleeper
Heart disease can be defined as any abnormality of the heart whether it is a cardiac dysrhythmia or structural heart disease, either congenital or acquired. Heart failure occurs when a cardiac abnormality results in the inability of the heart to pump enough blood to meet the body's needs. Heart disease can be present without leading to heart failure. Heart failure, however, is a consequence of heart disease. There are 4 main areas where the clinician can intervene to improve cardiac output with heart failure: preload, afterload, myocardial contractility, and heart rate...
April 2017: Veterinary Clinics of North America. Equine Practice
https://www.readbyqxmd.com/read/28325048/photoinduced-single-and-multiple-electron-dynamics-processes-enhanced-by-quantum-confinement-in-lead-halide-perovskite-quantum-dots
#10
Dayton Jon Vogel, Andrei Kryjevski, Talgat M Inerbaev, Dmitri S Kilin
Methyl-ammonium lead iodide perovskite (MAPbI3) is a promising material for photovoltaic devices. A modification of the MAPbI3 into confined nanostructures is expected to further increase efficiency of solar energy conversion. Photo-excited dynamic processes in a MAPbI3 quantum dot (QD) have been modeled by many-body perturbation theory and nonadiabatic dynamics. A photoexcitation is followed by either exciton cooling (EC), its radiative (RR) or non-radiative recombination (NRR), or multi-exciton generation (MEG) processes...
March 21, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28325030/application-of-meg-coherence-in-lateralization-of-mtle
#11
Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh
Magnetoencephalography (MEG) is a noninvasive imaging method for localization of focal epileptiform activity in patients with epilepsy. This study investigates the cerebral functional abnormalities quantified by MEG coherence laterality in mesial temporal lobe epilepsy (mTLE). Resting state MEG data was analyzed using MEG coherence source imaging (MEG-CSI) method to determine the coherence in 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender-matched controls. MEG coherence laterality, after Bonferroni adjustment, showed significant differences for right versus left mTLE in insular cortex and both lateral orbitofrontal and superior temporal gyri (p<;0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323961/normalized-early-post-operative-cortisol-and-acth-values-predict-nonremission-after-surgery-for-cushing-s-disease
#12
David Asuzu, Grégoire P Chatain, Christina Hayes, Sarah Benzo, Raven McGlotten, Meg Keil, Andrea Beri, Susmeeta T Sharma, Lynnette Nieman, Maya Lodish, Constantine Stratakis, Russell R Lonser, Edward H Oldfield, Prashant Chittiboina
Context: Perioperative increases in adrenocorticotropic hormone (ACTH) and cortisol mimic corticotropin releasing hormone (CRH) stimulation testing. This phenomenon may help identify patients with residual adenoma after transsphenoidal surgery (TSS) for Cushing's disease (CD). Objective: To predict non-remission after TSS for CD. Design: Retrospective case control study of patients treated at a single center from December 2003 till July 2016...
March 15, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28320094/lncrna-meg3-had-anti-cancer-effects-to-suppress-pancreatic-cancer-activity
#13
Lei Gu, Jiaqiang Zhang, Minmin Shi, Qian Zhan, Baiyong Shen, Chenghong Peng
AIM: The aim of this study was to explain the mechanism of lncRNA MEG 3 in pancreatic cancer. METHODS: We were collecting 30 pancreatic cancer patients, taking the sample from these patients. We measured the PI3K protein expressions from 30 patients by IHC and WB methods and MEG 3 expression by RT-PCR, and analyzed the relationship between PI3K protein expression and pancreatic cancer patients' clinical pathology and the correlation between lncRNA MEG 3 and PI3K...
March 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28319873/magnetoencephalography-with-temporal-spread-imaging-to-visualize-propagation-of-epileptic-activity
#14
Sumiya Shibata, Masao Matsuhashi, Takeharu Kunieda, Yukihiro Yamao, Rika Inano, Takayuki Kikuchi, Hisaji Imamura, Shigetoshi Takaya, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi, Tatsuya Mima, Hidenao Fukuyama, Nobuhiro Mikuni, Susumu Miyamoto
OBJECTIVE: We describe temporal spread imaging (TSI) that can identify the spatiotemporal pattern of epileptic activity using Magnetoencephalography (MEG). METHODS: A three-dimensional grid of voxels covering the brain is created. The array-gain minimum-variance spatial filter is applied to an interictal spike to estimate the magnitude of the source and the time (Ta) when the magnitude exceeds a predefined threshold at each voxel. This calculation is performed through all spikes...
January 30, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28317637/pyogenic-liver-abscess-due-to-fusobacterium-nucleatum-in-a-patient-with-liver-hemangiomas
#15
Theodoros Karantanos, Styliani Karanika, Kenechukwu Obiokoye, Meg Sullivan, Christine Phillips, Sonia Ananthakrishnan
No abstract text is available yet for this article.
April 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28316568/towards-a-functional-understanding-of-pgo-waves
#16
REVIEW
Jarrod A Gott, David T J Liley, J Allan Hobson
Ponto-Geniculo-Occipital (PGO) waves are biphasic field potentials identified in a range of mammalian species that are ubiquitous with sleep, but can also be identified in waking perception and eye movement. Their role in REM sleep and visual perception more broadly may constitute a promising avenue for further research, however what was once an active field of study has recently fallen into stasis. With the reality that invasive recordings performed on animals cannot be replicated in humans; while animals themselves cannot convey experience to the extent required to elucidate how PGO waves factor into awareness and behavior, innovative solutions are required if significant research outcomes are to ever be realized...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28316270/the-prosthetist-role-expectations-scale-development-and-initial-validation-of-a-scale-for-clinical-settings
#17
Renee L Mackenzie, Meg E Morris, Gregory Murphy, Margaret C Hodge
BACKGROUND: The role of the prosthetist has changed substantially over the past century. In the transition from 'limb-maker' to 'clinician', the expectations of prosthetics professionals have also changed. OBJECTIVES: To develop and test a new scale capable of assessing and comparing current expectations of the roles of the prosthetist. STUDY DESIGN: Scale development and validation. METHODS: A new scale was constructed in accordance with Organizational Role Theory...
March 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28315885/advancement-in-texture-in-early-complementary-feeding-and-the-relevance-to-developmental-outcomes
#18
Jordan R Green, Meg Simione, Benjamin Le Révérend, Erin M Wilson, Brian Richburg, Marc Alder, Mirna Del Valle, Chrystel Loret
A child's transition to independent eating is a protracted process that progresses over the course of many years. Although major health agencies, such as the World Health Organization, now offer clear guidance when to begin introducing solids, advice about how to safely transition to progressively challenging foods is varied and comes from a staggering number of sources. The resulting conflicting views have promoted parental confusion and anxiety about what foods are appropriate and when to advance to new textures...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28315461/single-or-multi-frequency-generators-in-on-going-brain-activity-a-mechanistic-whole-brain-model-of-empirical-meg-data
#19
Gustavo Deco, Joana Cabral, Mark W Woolrich, Angus B A Stevner, Tim J van Hartevelt, Morten L Kringelbach
During rest, envelopes of band-limited on-going MEG signals co-vary across the brain in consistent patterns, which have been related to resting-state networks measured with fMRI. To investigate the genesis of such envelope correlations, we consider a whole-brain network model assuming two distinct fundamental scenarios: one where each brain area generates oscillations in a single frequency, and a novel one where each brain area can generate oscillations in multiple frequency bands. The models share, as a common generator of damped oscillations, the normal form of a supercritical Hopf bifurcation operating at the critical border between the steady state and the oscillatory regime...
March 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28314121/comparative-validity-of-the-internet-and-paper-and-pencil-versions-of-the-night-eating-questionnaire
#20
Chao-Ying Tu, Mei-Chih Meg Tseng, Chin-Hao Chang, Chao-Cheng Lin
OBJECTIVE: This study examined the psychometric properties of the Internet and paper-and-pencil versions of the Mandarin Chinese version of the Night Eating Questionnaire (C-NEQ) and compared these measures' validity. METHOD: The C-NEQ was evaluated through two different media: 626 participants completed the C-NEQ on the Internet and 160 participants completed the paper-form C-NEQ at the psychiatric outpatient clinics. A subgroup completed both versions of the C-NEQ (n=50)...
March 6, 2017: Comprehensive Psychiatry
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