Setareh Azarkar, Masoud Abedi, Ali Sheikh Olya Lavasani, Atefeh Heidar Ammameh, Fatemeh Goharipanah, Kimiya Baloochi, Hasan Bakhshi, Amirsajad Jafari
Zoonotic diseases are major public health concerns and undeniable threats to human health. Among Zoonotic diseases, zoonotic viruses and prions are much more difficult to eradicate, as they result in higher infections and mortality rates. Several investigations have shown curcumin, the active ingredient of turmeric, to have wide spectrum properties such as anti-microbial, anti-vascular, anti-inflammatory, anti-tumor, anti-neoplastic, anti-oxidant, and immune system modulator properties. In the present study, we performed a comprehensive review of existing in silico, in vitro, and in vivo evidence on the antiviral (54 important zoonotic viruses) and anti-prion properties of curcumin and curcuminoids in PubMed, Google Scholar, Science Direct, Scopus, and Web of Science databases...
April 12, 2024: Phytotherapy Research: PTR