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https://www.readbyqxmd.com/read/29750603/differential-gene-expression-patterns-in-vein-regions-susceptible-versus-resistant-to-neointimal-hyperplasia
#1
Sun Hyung Kwon, Li Li, Christi M Terry, Yan-Ting Shiu, Philip J Moos, Brett A Milash, Alfred K Cheung, Donald K Blumenthal
Arteriovenous hemodialysis graft (AVG) stenosis results in thrombosis and AVG failure, and develops chiefly as a consequence of localized neointimal hyperplasia (NH) formation in the vein-graft anastomosis region. The vein region just downstream of the vein-graft anastomosis (herein termed proximal vein region) is relatively resistant to NH. Prevention of AVG stenosis has been ineffective due in part to our limited understanding of the molecular processes involved in NH formation. We hypothesized that the gene expression profiles of the NH-prone and NH-resistant regions will be different from each other after graft placement, and analysis of their genomic profiles may yield therapeutic targets to prevent AVG stenosis...
May 11, 2018: Physiological Genomics
https://www.readbyqxmd.com/read/29749910/a-novel-low-cost-reusable-high-fidelity-neurosurgical-training-simulator-for-cerebrovascular-bypass-surgery
#2
Ulas Cikla, Balkan Sahin, Sahin Hanalioglu, Azam S Ahmed, David Niemann, Mustafa K Baskaya
OBJECTIVE Cerebrovascular bypass surgery is a challenging yet important neurosurgical procedure that is performed to restore circulation in the treatment of carotid occlusive diseases, giant/complex aneurysms, and skull base tumors. It requires advanced microsurgical skills and dedicated training in microsurgical techniques. Most available training tools, however, either lack the realism of the actual bypass surgery (e.g., artificial vessel, chicken wing models) or require special facilities and regulations (e...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29747901/use-of-a-microvascular-coupler-device-for-end-to-side-venous-anastomosis-in-oral-and-maxillofacial-reconstruction
#3
W-M Wang, L Huang, X Gao, Y-X Yuan, X-Q Chen, X-C Jian
The aim of this study was to compare the use of a microvascular coupler device (MCD) for end-to-side venous anastomosis (ETS group) and phleboplasties combined with MCD for end-to-end venous anastomosis (ETE group) in free tissue transfer for oral and maxillofacial reconstruction, with regard to the anastomosis time and occurrence of postoperative vascular crisis. The ETS group included 22 patients and the ETE group included 40 patients. Patient demographic data, anastomotic time, coupler size, microvascular complications, and flap survival rates were collected and analyzed...
May 7, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29745216/how-to-compare-results-from-open-with-endovascular-procedures
#4
Marc Bosiers, Koen Deloose, Joren Callaert, Patrick Peeters, Jeroen Wauters
BACKGROUND: According to the guidelines, bypass surgery is still the golden standard treatment in patients with femoropopliteal TASC C and D lesions and life-style limiting claudication or CLI. Over the past few decades, endovascular therapy has made great advancements. However, the success rates of surgical and endovascular procedures cannot be directly compared. According to the surgical term "patency", vessel patency can be maintained even in case of a high grade stenosis, whereas according to the endovascular primary patency definition, being binary restenosis, patency is lost from the moment there is a re-narrowing at any location within the treated segment...
May 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29742454/the-pivotal-role-of-angiogenesis-in-a-multi-scale-modeling-of-tumor-growth-exhibiting-the-avascular-and-vascular-phases
#5
Hooman Salavati, M Soltani, Saeid Amanpour
The mechanisms involved in tumor growth mainly occur at the microenvironment, where the interactions between the intracellular, intercellular and extracellular scales mediate the dynamics of tumor. In this work, we present a multi-scale model of solid tumor dynamics to simulate the avascular and vascular growth as well as tumor-induced angiogenesis. The extracellular and intercellular scales are modeled using partial differential equations and cellular Potts model, respectively. Also, few biochemical and biophysical rules control the dynamics of intracellular level...
May 6, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29741975/introducing-anatomically-correct-ct-guided-laparoscopic-right-colectomy-with-d3-anterior-posterior-extended-mesenterectomy-initial-experience-and-technical-pitfalls
#6
Robin Gaupset, Jens Marius Nesgaard, Airazat M Kazaryan, Bojan V Stimec, Bjørn Edwin, Dejan Ignjatovic
BACKGROUND: Laparoscopic D3 anterior posterior extended mesenterectomy (D3APEM) in right colectomy has received increased attention. The aim of this study is to prove feasibility, systemize technical accomplishment, and provide short-term outcomes data. METHODS: From July 2013 to February 2017, 18 patients with adenocarcinoma in the right colon underwent right colectomy with laparoscopic D3APEM, including lymph nodes anterior and posterior to the superior mesenteric vessels...
May 9, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29740586/supermicrosurgery-history-applications-training-and-the-future
#7
Ido Badash, Daniel J Gould, Ketan M Patel
Supermicrosurgery, a technique of dissection and anastomosis of small vessels ranging from 0.3 to 0.8 mm, has revolutionized the fields of lymphedema treatment and soft tissue reconstruction. The technique offers several distinct benefits to microsurgeons, including the ability to manipulate small vessels that were previously inaccessible, and to minimize donor-site morbidity by dissecting short pedicles in a suprafascial plane. Thus, supermicrosurgery has become increasingly popular in recent years, and its applications have greatly expanded since it was first introduced 20 years ago...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29739918/electrospinning-of-highly-concentrated-albumin-patches-by-using-auxiliary-polymers-for-laser-assisted-vascular-anastomosis
#8
Annemarie Schönfeld, Mihai Constantinescu, Kirsten Peters, Martin Frenz
Electrospun meshes have been extensively investigated for tissue engineering and drug delivery. The application of this technology is of interest for laser-assisted vascular anastomosis (LAVA) due to the possibility to bind and stabilize macromolecules in fibers.
 Materials and Methods: We prepared bovine serum albumin (BSA) blend microfibers from the auxiliary proteins polyethylene oxide (PEO), polycaprolactone (PCL), polyvinyl alcohol (PVA) and gelatin. The thickness and weight of the resulting patches were measured and the morphological characteristics were observed by scanning electron microscopy...
May 9, 2018: Biomedical Materials
https://www.readbyqxmd.com/read/29736923/reconstruction-of-complex-tissue-defect-of-forearm-with-a-chimeric-flap-composed-of-a-sural-neurocutaneous-flap-and-a-vascularized-fibular-graft-a-case-report
#9
Chunyang Wang, Jia Xu, Gen Wen, Yimin Chai
One-stage reconstruction of composite bone and soft-tissue defects in the forearm remains a tough challenge. Here, we present a case of reconstruction of complex tissue defect at forearm with a chimeric flap consisting of a sural neurocutaneous flap and a fibular graft. A 61-year-old man suffered from a machine crush injury in his left forearm, resulting in a complex tissue defect including extensive dorsomedial soft-tissue, digit extensor muscles of 2-4 fingers, the muscle flexor carpi ulnaris, the ulna bone with 5...
May 7, 2018: Microsurgery
https://www.readbyqxmd.com/read/29731085/comparison-of-two-devices-for-intraoperative-portal-venous-flow-measurement-in-living-donor-liver-transplantation-transit-time-ultrasound-and-conventional-doppler-ultrasound
#10
H-K Wang, C-Y Chen, N-C Lin, C-S Liu, C-C Loong, Y-H Lin, Y-C Lai, H-J Chiou
BACKGROUND: Intraoperative portal venous flow measurement provides surgeons with instant guidance for portal flow modulation during living-donor liver transplantation (LDLT). In this study, we compared the agreement of portal flow measurement obtained by 2 devices: transit time ultrasound (TTU) and conventional Doppler ultrasound (CDU). METHODS: Fifty-four recipients of LDLT underwent intraoperative measurement of portal flow after completion of vascular anastomosis of the implanted partial liver graft...
May 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29731074/postoperative-doppler-ultrasonography-in-liver-transplantation
#11
Y K Chung, H J Choi, G H Na, Y K You, I Y Park
BACKGROUND: Doppler ultrasonography plays an important role in the postoperative management of liver transplantation. We present our initial experiences evaluating liver transplants with the use of postoperative Doppler sonography. METHODS: In our hospital, we performed 20 liver transplantations from July 2014 to October 2016. Among 20 patients, we performed 15 deceased-donor liver transplantations (DDLTs) and 5 living-donor liver transplantations (LDLTs). For deceased donors, inferior vena cava anastomoses were performed with the use of the piggyback technique, and for living donors, modified right grafts were used with middle hepatic vein reconstruction by Dacron graft...
May 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29729474/the-in-situ-side-to-side-bypass-technique-a-comprehensive-review-of-the-technical-characteristics-current-anastomosis-approaches-and-surgical-experience
#12
REVIEW
Long Wang, Li Cai, Hai Qian, Michael T Lawton, Xiang'en Shi
OBJECTIVE: In situ side-to-side (STS) revascularization is an intracranial-intracranial (IC-IC) bypass technique that is increasingly used to treat complex aneurysms and cerebral ischemia. This sophisticated technique involves connecting two proximal parallel vessels to create an artificial conduit for blood flow. This study aims to provide a detailed description of the configuration of the STS bypass technique and extensive information regarding its technical characteristics, current anastomosis approaches and surgical significance...
May 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29726780/intrinsic-development-of-choroidal-and-thalamic-collaterals-in-hemorrhagic-onset-moyamoya-disease-case-control-study-of-the-japan-adult-moyamoya-trial
#13
Miki Fujimura, Takeshi Funaki, Kiyohiro Houkin, Jun C Takahashi, Satoshi Kuroda, Yasutake Tomata, Teiji Tominaga, Susumu Miyamoto
OBJECTIVE This study was performed to identify the angiographic features of hemorrhagic-onset moyamoya disease (MMD) in comparison with those of patients with ischemic-onset MMD. METHODS This case-control study compared the data set of the Japan Adult Moyamoya (JAM) Trial with the angiographic data of adult patients with ischemic-onset MMD. The authors analyzed angiograms obtained at onset, classifying the collaterals into 3 subtypes: lenticulostriate anastomosis, thalamic anastomosis, and choroidal anastomosis...
May 4, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29726640/-establishment-of-a-penile-transplantation-model-in-beagle-dogs
#14
Yong-Bin Zhao, Wei-Lie Hu, Li-Chao Zhang, Jun Liu, Chang-Zheng Zhang, Bang-Qi Wang, Yuan-Song Xiao, Hui Hu, Ming Ying
Objective: To investigate the feasibility of establishing a model of allograft penile transplantation in adult beagle dogs and explore the conditions for constructing a stable animal model of penis transplant. METHODS: Following the principles of similarity, repeatability, feasibility, applicability, and controllability in the construction of experimental animal models, we compared the major anatomic features of the penis of 20 adult beagle dogs with those of 10 adult men...
August 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29723419/vein-resection-during-pancreaticoduodenectomy-for-pancreatic-adenocarcinoma-patency-rates-and-outcomes-associated-with-thrombosis
#15
Rebecca A Snyder, Laura R Prakash, Graciela M Nogueras-Gonzalez, Michael P Kim, Thomas A Aloia, Jean-Nicolas Vauthey, Jeffrey E Lee, Jason B Fleming, Matthew H G Katz, Ching-Wei D Tzeng
BACKGROUND AND OBJECTIVES: Venous patency rates after pancreaticoduodenectomy (PD) with portal vein (PV) resection are not well established, and the oncologic impact of portal vein thrombosis (PVT) is unknown. The primary aim of this study was to determine rates and predictors of PVT after PD with PV resection for pancreatic adenocarcinoma (PDAC). METHODS: A retrospective cohort study was performed on PDAC patients treated with preoperative therapy and PD with PV resection at a high-volume institution (2008-15)...
May 3, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29716634/successful-fertility-following-optimized-perfusion-and-cryopreservation-of-whole-ovary-and-allotransplantation-in-a-premature-ovarian-insufficiency-rat-model
#16
Yan Ding, Jia-Liang Shao, Jun-Wei Li, Ying Zhang, Kai-Hua Hong, Ke-Qin Hua, Xiang Wang
BACKGROUND: Fertility preservation by whole ovary cryopreservation and transplantation (WOCP&TP) with vascular anastomosis requires successful cryopreservation. In this study, we investigated the possibility of restoring ovarian function and natural fertility after WOCP&TP in a premature ovarian insufficiency (POI) rat model. The influence of cryopreservation on the offspring of rats following WOCP&TP was also explored. METHOD: Rats aged 8-10 weeks were used as donors and recipients for allotransplantation...
May 2, 2018: Journal of Ovarian Research
https://www.readbyqxmd.com/read/29715235/-moneyball-comes-to-replantation-how-we-assess-our-work-commentary-on-an-article-by-hongyi-zhu-md-et-al-patency-test-of-vascular-anastomosis-with-assistance-of-high-speed-video-recording-in-digit-replantation
#17
https://www.readbyqxmd.com/read/29715220/patency-test-of-vascular-anastomosis-with-assistance-of-high-speed-video-recording-in-digit-replantation
#18
Hongyi Zhu, Xiaozhong Zhu, Changqing Zhang, Xianyou Zheng
BACKGROUND: Quality assessment of vascular anastomosis primarily depends on the experience of the treating surgeon. This highlights the need for an objective index. The main goal of our study was to establish a method of assessing the quality of vascular anastomosis in digit replantation. METHODS: A total of 182 digits from 141 patients were included in this study. The patients underwent replantation of completely amputated digits between June 1, 2015, and February 1, 2017...
May 2, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29713738/fetal-median-sacral-artery-anatomy-study-by-micro-ct-imaging
#19
P Meignan, A Binet, A R Cook, H Lardy, G Captier
PURPOSE: The median sacral artery (MSA) is the termination of the dorsal aorta, which undergoes a complex regression and remodeling process during embryo and fetal development. The MSA contributes to the pelvic vascularization and may be injured during pelvic surgery. The embryological steps of MSA development, anastomosis formation and anatomical variations are linked, but not fully understood. METHODS: The pelvic vascularization and more precisely the MSA of a human fetus at 22 weeks of gestation (GW) were studied using micro-CT imaging...
April 30, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29707508/tracheal-release-maneuvers
#20
Brett Broussard, Douglas J Mathisen
Tracheal resection and reconstruction has been slow to develop in the field of thoracic surgery. The ability to perform a low tension, well-vascularized anastomosis with good outcomes has improved with understanding of tracheal blood supply and the ability to perform tracheal release maneuvers. Laryngeal and suprahyoid release maneuvers can be helpful for cervical tracheal resections, while hilar and pericardial release maneuvers can be beneficial in thoracic tracheal resections. Simple maneuvers such as neck flexion and dissection of the avascular pretracheal plane can also be used to improve anastomotic tension...
March 2018: Annals of Cardiothoracic Surgery
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