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https://www.readbyqxmd.com/read/29275276/fragile-x-associated-premature-ovarian-failure-in-a-large-turkish-cohort-findings-of-hacettepe-fragile-x-registry
#1
Gülen Eda Utine, Pelin Özlem Şimşek-Kiper, Özlem Akgün-Doğan, Gizem Ürel-Demir, Yasemin Alanay, Dilek Aktaş, Koray Boduroğlu, Ergül Tunçbilek, Mehmet Alikaşifoğlu
OBJECTIVE: To determine frequency of fragile X associated premature ovarian insufficiency (FXPOI) among Turkish premutation carriers. STUDY DESIGN: FMR1 premutation is the single most common genetic cause of POI (FXPOI). Fragile X Registry at Hacettepe University has been reviewed for the frequency of FXPOI among female premutation carriers. Since 1991 when FMR1 testing was available, 760 individuals from 243 families have been registered. Actual data on menstrual status of female premutation carriers were gathered and analysed...
December 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29258166/pofbg-embedded-cork-insole-for-plantar-pressure-monitoring
#2
Débora Vilarinho, Antreas Theodosiou, Cátia Leitão, Arnaldo G Leal-Junior, Maria de Fátima Domingues, Kyriacos Kalli, Paulo André, Paulo Antunes, Carlos Marques
We propose a novel polymer optical fiber (POF) sensing system based on fiber Bragg gratings (FBGs) to measure foot plantar pressure. The plantar pressure signals are detected by five FBGs, in the same piece of cyclic transparent optical polymer (CYTOP) fiber, which are embedded in a cork insole for the dynamic monitoring of gait. The calibration and measurements performed with the suggested system are presented, and the results obtained demonstrate the accuracy and reliability of the sensing platform to monitor the foot plantar pressure distribution during gait motion and the application of pressure...
December 16, 2017: Sensors
https://www.readbyqxmd.com/read/29242291/the-x-linked-1-688-satellite-in-drosophilamelanogaster-promotes-specific-targeting-by-painting-of-fourth
#3
Maria Kim, Samaneh Ekhteraei-Tousi, Jacob Lewerentz, Jan Larsson
Repetitive DNA, represented by transposons and satellite DNA, constitutes a large portion of eukaryotic genomes, being the major component of constitutive heterochromatin. There is a growing body of evidence that it regulates several nuclear functions including chromatin state and the proper functioning of centromeres and telomeres. The 1.688 satellite is one of the most abundant repetitive sequences in Drosophilamelanogaster, with the longest array being located in the pericentromeric region of the X-chromosome...
December 13, 2017: Genetics
https://www.readbyqxmd.com/read/29236082/low-cost-plastic-optical-fiber-pressure-sensor-embedded-in-mattress-for-vital-signal-monitoring
#4
Demetrio Sartiano, Salvador Sales
The aim of this paper is to report the design of a low-cost plastic optical fiber (POF) pressure sensor, embedded in a mattress. We report the design of a multipoint sensor, a cheap alternative to the most common fiber sensors. The sensor is implemented using Arduino board, standard LEDs for optical communication in POF (λ = 645 nm) and a silicon light sensor. The Super ESKA® plastic fibers were used to implement the fiber intensity sensor, arranged in a 4 × 4 matrix. During the breathing cycles, the force transmitted from the lungs to the thorax is in the order of tens of Newtons, and the respiration rate is of one breath every 2-5 s (0...
December 13, 2017: Sensors
https://www.readbyqxmd.com/read/29233755/postoperative-fasting-after-general-anaesthesia-a-survey-of-french-anaesthesiology-practices
#5
Sylvain Le Pape, Matthieu Boisson, Thibault Loupec, FabienVigneau, Bertrand Debaene, Denis Frasca
BACKGROUND: Preoperative fasting is well-codified worldwide. In contrast, the literature on the postoperative fasting (POF) is scarce leading to potentially wide discrepancies among anaesthesiology practices. This survey assessed French POF practices. METHODS: From March 2013 to January 2014, a survey was conducted among anaesthesiologists, members of the French Society of Anaesthesiology and Critical Care. The POF durations of either fluid or solid food intake was assessed according to airway management procedures (endotracheal intubation [EI] or laryngeal mask [LMA]) and age of the patients (adult or paediatric)...
December 9, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29231439/-professor-lai-xinsheng-s-clinical-experience-in-the-treatment-of-premature-ovarian-failure-with-tongyuan-acupuncture-technique-and-chinese-herbal-medicine
#6
Xiaozhe Li, Sujuan Zhang
In the treatment of premature ovarian failure (POF), professor LAI Xinsheng focuses on the determination of syndrome to seek for etiology, associating with the differentiation of meridian and collateral and that of zangfu organs. Professor LAI believes that POF is mainly manifested as amenorrhea and infertility, localized in the kidney, with the dysfunction of liver, spleen and heart. It is impacted by many pathological factors, such as cold blockage, qi stagnation, blood stagnation, blood deficiency, yin deficiency, etc...
March 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29221040/polymethyl-methacrylate-pmma-recycling-for-the-production-of-optical-fiber-sensor-systems
#7
Adilson R Prado, Arnaldo G Leal-Junior, Carlos Marques, Samara Leite, Geovane L de Sena, Luiz C Machado, Anselmo Frizera, Moises R N Ribeiro, Maria José Pontes
This paper proposes the recycling of poly (methyl methacrylate) plates, formerly used in LCD monitors to produce polymer optical fibers without cladding for sensor systems and a discussion about the fabrication process of the fiber cladding is briefly presented. After disassembling LCD monitors the acrylic plate is cleaned and submitted to an extrusion process. Extrusion temperatures of 220°C, 230°C and 240°C were applied, and the produced polymer fibers were characterized by infrared and visible spectrometry, as well as evaluated for thermal analysis through differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA)...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29200137/early-prediction-of-persistent-organ-failure-by-circulating-endothelial-progenitor-cells-in-patients-with-acute-pancreatitis
#8
Jun Liu, Gui-Juan Zou, Long Yang, Shu Rong, Bai-Qiang Li, Zhi-Hui Tong, Wei-Qin Li, Jie-Shou Li
INTRODUCTION: Increased circulating endothelial progenitor cells (cEPC) have been observed in patients with vascular injury associated with sepsis and acute lung injury. However, a role for cEPC in severe acute pancreatitis (SAP) remains unclear. We therefore conducted a prospective study to study whether the quantities of cEPC can predict persistent organ failure (POF) in patients with predicted SAP. METHODS: A total of 42 predicted SAP patients who were admitted within 24 hours after symptom onset and 10 healthy control subjects were enrolled in our study...
December 1, 2017: Shock
https://www.readbyqxmd.com/read/29196048/developmental-competence-and-apoptotic-gene-expression-patterns-of-mature-and-immature-human-oocytes-retrieved-from-controlled-ovarian-stimulation-cycles
#9
Farzaneh Fesahat, Mohammad Hasan Sheikhha, Seyed Mehdi Kalantar, Nasim Tabibnejad, Razieh Dehghani Firouzabadi, Hojjatollah Saeedi, Mohammad Ali Khalili
The purpose was to assess the developmental competence of the in vitro or in vivo matured human oocytes as well as the apoptotic genes expression of cumulus cells (CCs) regarding nuclear maturity status of associated oocytes retrieved from stimulated ICSI cycles. A total of 590 oocytes and the associated CCs were retrieved and divided into groups of test and control according to the nuclear maturity status in order to the developmental evaluation as well as expression patterns of apoptosis-related genes using real time PCR...
November 28, 2017: Reproductive Biology
https://www.readbyqxmd.com/read/29181820/role-of-trace-elements-oxidative-stress-and-immune-system-a-triad-in-premature-ovarian-failure
#10
Priyanka Verma, Aparna K Sharma, Hari Shankar, Alpana Sharma, D N Rao
The risk of premature ovarian failure (POF) increases in association with alteration in immunological parameters and oxidative stress (OS). Adequate intake of trace elements is required for antioxidant property and immune defense mechanism. The aim of this study was to explore the involvement of trace elements, OS, and immunological parameters in POF. This was a cross-sectional, case-control study, involving 65 participants divided into the POF (n = 35) and control (n = 30) groups. Serum levels of Se, Zn, and Cu were determined along with hormonal, OS, and immunological markers...
November 27, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29180824/genetic-architecture-and-candidate-genes-identified-for-follicle-number-in-chicken
#11
Manman Shen, Hongyan Sun, Liang Qu, Meng Ma, Taocun Dou, Jian Lu, Jun Guo, Yuping Hu, Xingguo Wang, Yongfeng Li, Kehua Wang, Ning Yang
Follicular development has a major impact on reproductive performance. Most previous researchers focused on molecular mechanisms of follicular development. The genetic architecture underlying the number of follicle, however, has yet not to be thoroughly defined in chicken. Here we report a genome-wide association study for the genetic architecture determining the numbers of follicles in a large F2 resource population. The results showed heritability were low to moderate (0.05-0.28) for number of pre-ovulatory follicles (POF), small yellow follicles (SYF) and atresia follicles (AF)...
November 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29179771/paracrine-effects-of-human-amniotic-epithelial-cells-protect-against-chemotherapy-induced-ovarian-damage
#12
Qiuwan Zhang, Shixia Bu, Junyan Sun, Minhua Xu, Xiaofen Yao, Kunyan He, Dongmei Lai
BACKGROUND: Human amniotic epithelial cells (hAECs) are attractive candidates for regenerative medical therapy, with the potential to replace deficient cells and improve functional recovery after injury. Previous studies have demonstrated that transplantation of hAECs effectively alleviate chemotherapy-induced ovarian damage via inhibiting granulose cells apoptosis in animal models of premature ovarian failure/insufficiency (POF/POI). However, the underlying molecular mechanism accounting for hAECs-mediated ovarian function recovery is not fully understood...
November 28, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29170104/unraveling-unusual-x-chromosome-patterns-during-fragile-x-syndrome-genetic-testing
#13
Gabriella Esposito, Maria Roberta Tremolaterra, Maria Savarese, Michele Spiniello, Maria Pia Patrizio, Barbara Lombardo, Lucio Pastore, Francesco Salvatore, Antonella Carsana
BACKGROUND: Fragile X syndrome (FXS) is the most common form of inherited intellectual disability (ID). Together with fragile X-associated tremor and ataxia (FXTAS) and fragile X-associated premature ovarian failure (POF)/primary ovarian insufficiency (POI), depends on dysfunctional expression of the FMR1 gene on Xq27.3. In most cases, FXS is caused by a >200 CGG repeats in FMR1 5'-untranslated region (UTR) and by promoter hypermethylation that results in gene silencing. Males and females with unmethylated premutated alleles (repeats between 55 and 200) are at risk for FXTAS and POF/POI...
November 20, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29144824/17%C3%AE-hydroxylase-deficiency-is-an-underdiagnosed-disease-high-frequency-of-misdiagnoses-in-a-large-cohort-of-brazilian-patients
#14
Rafaela Fontenele, Marivânia Costa-Santos, Claudio E Kater
OBJECTIVE: 17α-Hydroxylase deficiency (P450c17D) is characterized by hypogonadism and mineralocorticoid hypertension. We aimed to estimate the relative incidence and spectrum of preliminary misdiagnoses in Brazilian P450c17D patients. DESIGN: Cross-sectional study. METHODS: We reviewed, updated, and analyzed data of 40 P450c17D patients (21 XY, 19 XX). RESULTS: Complete data were unavailable for two patients. Seven patients were relatives of an index case...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29128702/effects-of-preovulatory-follicle-size-on-estradiol-concentrations-corpus-luteum-diameter-progesterone-concentrations-and-subsequent-pregnancy-rate-in-buffalo-cows-bubalus-bubalis
#15
A K Pandey, S P S Ghuman, G S Dhaliwal, M Honparkhe, J B Phogat, S Kumar
The present study was undertaken to investigate the effects of preovulatory follicle (POF) size on estradiol concentrations, luteal profile (CL diameter and progesterone concentration) and subsequent pregnancy rate in Murrah buffalo cows. The buffalo cows (n = 49) were synchronized for estrus by two doses of PGF2α given 11 days apart. The buffalo cows were inseminated during standing estrus and again after 24 h. Ovaries were scanned at estrus and 24 h intervals until ovulation, thereafter on days 5, 12 and 16 post-ovulation to examine the POF and CL diameter...
November 4, 2017: Theriogenology
https://www.readbyqxmd.com/read/29105397/the-impact-of-genetic-variation-and-gene-expression-level-of-the-follicle-stimulating-hormone-receptor-on-ovarian-reserve
#16
Zeinab Ghezelayagh, Mehdi Totonchi, Shabnam Zarei-Moradi, Ommolbanin Asadpour, Saman Maroufizadeh, Poopak Eftekhari-Yazdi, Hamid Gourabi, Anahita Mohseni-Meybodi
OBJECTIVES: Ovarian reserve is defined as the capacity of the ovary to provide fertile oocytes. Diminished ovarian reserve (DOR) is a disorder in which ovaries are prone to go through early menopause. Where this loss of function occurs before the age of 40, it results in the premature ovarian failure (POF) disease. Throughout folliculogenesis, the follicle-stimulating hormone receptor (FSHR) starts a signaling cascade in the granulosa cells where its inactivation leads to the arrest of follicle maturation and therefore adversely affects ovarian reserve...
January 2018: Cell Journal
https://www.readbyqxmd.com/read/29091704/wet-etching-technique-for-fabrication-of-a-high-quality-plastic-optical-fiber-sensor
#17
Mingfu Zhao, Lang Dai, Nianbing Zhong, Zhengkun Wang, Ming Chen, Bingxin Li, Binbin Luo, Bin Tang, Shenghui Shi, Tao Song, Xue Zou
In this study, a simple wet etching technique is developed by employing aqueous solutions of acetic acid and ultrasonic irradiation for the fabrication of a high-quality plastic optical fiber (POF) sensor. The effects of acetic acid concentration and temperature and ultrasonic power on the etching rate and surface morphology of the etched POFs are investigated. The transmission spectrum and sensitivity of the etched POF sensors are evaluated using glucose solutions. We discovered that the POF sensors, which are fabricated using an aqueous solution of acetic acid with a concentration of 80 vol...
November 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29082067/pof-yarn-weaves-controlling-the-light-out-coupling-of-wearable-phototherapy-devices
#18
Brit M Quandt, Marisa S Pfister, Jörn F Lübben, Fabrizio Spano, René M Rossi, Gian-Luca Bona, Luciano F Boesel
Neonatal jaundice (hyperbilirubinaemia) is common in neonates and, often, intensive blue-light phototherapy is required to prevent long-term effects. A photonic textile can overcome three major incubator-related concerns: Insulation of the neonate, human contact, and usage restraints. This paper describes the development of a homogeneous luminous textile from polymer optical fibres to use as a wearable, long-term phototherapy device. The bend out-coupling of light from the POFs was related to the weave production, e...
October 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/29074033/pre-ovulatory-follicle-affects-corpus-luteum-diameter-blood-flow-and-progesterone-production-in-mares
#19
G M Ishak, S T Bashir, M O Gastal, E L Gastal
Color Doppler ultrasonography was used to study the temporal relationships between pre-ovulatory follicle (POF) and corpus luteum (CL) diameter and blood flow, with systemic progesterone (P4) concentration during two transitional ovulatory seasons in mares. Variables of POF and CL/P4 were evaluated for 6days before and 17days after ovulation, respectively. Evaluations were performed during two consecutive estrous cycles in spring and fall seasons, and during the last estrous cycle of the season. There were significant correlations among POF and CL variables, and P4 concentration that ranged from 0...
September 8, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/29069189/nutritional-status-of-children-under-5-years-of-age-in-brazil-evidence-of-nutritional-epidemiological-polarisation
#20
Ingrid Freitas da Silva Pereira, Lára de Melo Barbosa Andrade, Maria Helena Constatino Spyrides, Clélia de Oliveira Lyra
The objective of this study was to evaluate the nutritional status of children under 5 years of age in Brazil in 2009 and its association with social and demographic factors. Data from the Household Budget Survey (Pesquisa de Orçamento Familiar - POF 2008-2009) were used, in which the nutritional profile was evaluated according to the weight-for-age (W/A), height-for-age (H/A) and weight-for-height (W/H) indices (n = 14,569). The association was estimated by applying the Pearson association test, a logistic regression and a correspondence analysis...
October 2017: Ciência & Saúde Coletiva
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