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empty follicle syndrom

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https://www.readbyqxmd.com/read/27477178/trichotillomania-bizzare-patern-of-hair-loss-at-11-year-old-girl
#1
Jana Zímová, Pavlína Zímová
Trichotillomania (TTM) is defined by the Diagnostics and Statistic Manual of Mental Disorders, 4th edition (DMS-IV) as hair loss from a patient`s repetitive self-pulling of hair. The disorder is included under anxiety disorders because it shares some obsessive-compulsive features. Patients have the tendency towards feelings of unattractiveness, body dissatisfaction, and low self-esteem (1,2). It is a major psychiatric problem, but many patients with this disorder first present to a dermatologist. An 11-year-old girl came to our department with a 2-month history of diffuse hair loss on the frontoparietal and parietotemporal area (Figure 1)...
June 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27451069/-is-gonadotropin-releasing-hormone-gnrh-agonist-trigger-beneficial-or-deleterious
#2
M Le Chatton, C Wittemer, T Schweitzer, F Lestrade, J-P Ragage
OBJECTIVES: The undeniable asset of the antagonist protocols in in vitro fertilization is the decrease of the risks of ovarian hyperstimulation syndrome, by the use of a release by GnRH agonist. Nevertheless, questioning persist concerning the rates of clinical pregnancies, the oocyte quantity and the empty follicle syndrome. We thus studied these parameters in our center. METHODS: A retrospective study was realized from January 1st, 2013 till July 31st, 2015...
July 2016: Gynécologie, Obstétrique & Fertilité
https://www.readbyqxmd.com/read/27275861/combined-ovulation-triggering-with-gnrh-agonist-and-hcg-in-ivf-patients
#3
Miro Kasum, Kristijan Kurdija, Slavko Orešković, Ermin Čehić, Dinka Pavičić-Baldani, Lana Škrgatić
The aim of the review is to analyse the combination of a gonadotrophin releasing hormone (GnRH) agonist with a human chorionic gonadotrophin (hCG) trigger, for final oocyte maturation in in vitro fertilisation (IVF) cycles. The concept being a ''dual trigger'' combines a single dose of the GnRH agonist with a reduced or standard dosage of hCG at the time of triggering. The use of a GnRH agonist with a reduced dose of hCG in high responders demonstrated luteal phase support with improved pregnancy rates, similar to those after conventional hCG and a low risk of ovarian hyperstimulation syndrome (OHSS)...
June 8, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/26675755/empty-follicle-syndrome-the-possible-cause-of-occurrence
#4
Tahereh Madani, Nadia Jahangiri
OBJECTIVES: Empty follicle syndrome (EFS), although rare, is a disappointing condition in which no oocytes are retrieved from mature follicle after ovulation induction in in vitro fertilization (IVF) cycles. The aim of this study was to estimate the incidence and factors associated with EFS. METHODS: All cycles resulting in EFS from May 2012 to September 2013 were retrospectively identified at a tertiary referral infertility center. Among the 3,356 cycles performed, 58 (1...
November 2015: Oman Medical Journal
https://www.readbyqxmd.com/read/26538861/empty-follicle-syndrome-successful-pregnancy-following-dual-trigger
#5
K Deepika, Suvarna Rathore, Nupur Garg, Kamini Rao
Empty follicle syndrome (EFS) is an uncommon, but the frustrating complication of assisted reproductive technology with failure to obtain oocytes after an adequate ovarian response to stimulation. Most of the reported cases of EFS are drug-related problems which are actually avoidable and do not represent any potential pathology and that the risk of genuine EFS (GEFS) is much smaller than was once thought. Our case is the first report of a pregnancy obtained after management of GEFS with dual trigger in a gonadotropin-releasing hormone (GnRH) antagonist cycle...
July 2015: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/25385007/co-administration-of-gnrh-agonist-and-hcg-for-final-oocyte-maturation-double-trigger-in-patients-with-low-proportion-of-mature-oocytes
#6
COMPARATIVE STUDY
Eran Zilberberg, Jigal Haas, Shir Dar, Alon Kedem, Ronit Machtinger, Raoul Orvieto
OBJECTIVE: Human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH), as a surrogate LH surge, to induce final oocyte maturation and resumption of meiosis. Recently, the co-administration of GnRH agonist and hCG for final oocyte maturation - 40 and 34 h prior to OPU, respectively (double trigger) was suggested to improve IVF outcome in patient with genuine empty follicle syndrome. In the present study, we aim to evaluate whether the double trigger might improve the proportions of metaphase-II (MII) oocytes in patients with low proportion of mature oocytes (<66%) per number oocytes retrieved...
February 2015: Gynecological Endocrinology
https://www.readbyqxmd.com/read/25330695/pituitary-mass-and-subsequent-involution-causing-fluctuations-of-serum-follicle-stimulating-hormone-levels-in-a-turner-syndrome-patient-with-premature-ovarian-failure-a-case-report
#7
Helene S Weibel, Michael H Dahan
BACKGROUND: Premature ovarian failure (POF) is described as estrogen deficiency, amenorrhea, and hypergonadotropinemia in a woman < 40 years old. In a proportion of patients diagnosed with POF, intermittent and unpredictable return of ovarian function can be observed, causing fluctuations of follicle-stimulating hormone (FSH). However, these patients also have return of menstrual cycles. When cycles do not resume, other causes could explain the changes in FSH levels. CASE: A 43-year-old woman with known premature ovarian failure since age 23 and high serum FSH levels was referred for normalization of FSH levels...
September 2014: Journal of Reproductive Medicine
https://www.readbyqxmd.com/read/25296696/co-administration-of-gnrh-agonist-and-hcg-for-final-oocyte-maturation-double-trigger-in-patients-with-low-number-of-oocytes-retrieved-per-number-of-preovulatory-follicles-a-preliminary-report
#8
Jigal Haas, Eran Zilberberg, Shir Dar, Alon Kedem, Ronit Machtinger, Raoul Orvieto
BACKGROUND: Recently, the co-administration of GnRH agonist and hCG for final oocyte maturation- 40 and 34 hours prior to OPU, respectively (double trigger) was suggested as the treatment of genuine empty follicle syndrome. In the present study, we aim to evaluate whether the double trigger improves the number of oocytes retrieved in patients with low (<50%) number of oocytes retrieved per number of preovulatory follicles. METHODS: In this proof of concept cohort historical study, we compared the stimulation characteristics of 8 IVF cycles, which include the double trigger to the patients' previous IVF attempt, triggered with hCG-only...
2014: Journal of Ovarian Research
https://www.readbyqxmd.com/read/25085799/empty-follicle-syndrome-prevalence-and-management-in-oocyte-donors
#9
Anna Blazquez, Juan José Guillén, Clara Colomé, Oriol Coll, Rita Vassena, Valerie Vernaeve
STUDY QUESTION: Is the drug used for final oocyte maturation a factor in determining the prevalence of empty follicle syndrome (EFS)? SUMMARY ANSWER: The drug used for final oocyte maturation is not a factor in determining the prevalence of EFS among women unaffected by infertility. WHAT IS KNOWN ALREADY: Despite satisfactory follicular stimulation and adequate follicular development, cases of EFS, i.e. failure to recover any cumulus oocyte complex, have been reported both with hCG and GnRH agonist triggering...
October 10, 2014: Human Reproduction
https://www.readbyqxmd.com/read/24842349/recurrent-hypoglycaemia-a-delayed-presentation-of-sheehan-syndrome
#10
Naresh Kumar, Pratap Singh, Jyoti Kumar, Dinesh Kumar Dhanwal
Sheehan syndrome is a rare but potentially serious complication of postpartum haemorrhage. The diagnosis can often be delayed by many years as symptoms may be subtle. We report the case of a 45-year-old woman who presented to the medical emergency unit with acute onset altered sensorium. On further evaluation she was found to have severe hypoglycaemia which was corrected by giving intravenous dextrose. On detailed clinical evaluation, she had a history of agalactia and amenorrhoea following her last pregnancy which was 15 years ago...
2014: BMJ Case Reports
https://www.readbyqxmd.com/read/23565413/empty-sella-syndrome-beyond-being-an-incidental-finding
#11
Vikrant Ghatnatti, Dipti Sarma, Uma Saikia
INTRODUCTION: Empty sella is characterized by the herniation of the subarachnoid space within the sella, which is often associated with some degree of flattening of the pituitary gland. This study was undertaken to evaluate the clinical and hormonal profile in patients with empty sella. AIMS AND OBJECTIVES: To evaluate the clinical and hormonal profile of the patients with an empty sella. MATERIALS AND METHODS: Patients undergoing a CT/MRI at our center, for various reasons but with the finding of the empty sella were included in this study...
December 2012: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/23346522/empty-follicle-syndrome
#12
Jee Hyun Kim, Byung Chul Jee
Empty follicle syndrome (EFS) is a condition in which no oocytes are retrieved after an apparently adequate ovarian response to stimulation and meticulous follicular aspiration. EFS can be classified into 'genuine' and 'false' types according to hCG levels. It is a rare condition of obscure etiology. The existence of genuine EFS has been questioned and is still controversial. The limitation around EFS is that the definition of EFS is obscure. Management of patients with EFS is a challenge to physicians. No single treatment is known to be universally effective...
December 2012: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/23077235/predicting-successful-induction-of-oocyte-maturation-after-gonadotropin-releasing-hormone-agonist-gnrha-trigger
#13
N E Kummer, R S Feinn, D W Griffin, J C Nulsen, C A Benadiva, L L Engmann
STUDY QUESTION: Are there factors predicting the number of total and mature oocytes retrieved after controlled ovarian hyperstimulation (COH) utilizing a gonadotropin-releasing hormone (GnRH) antagonist protocol and a GnRH agonist (GnRHa) to induce oocyte maturation? SUMMARY ANSWER: Peak estradiol (E₂) level, post-trigger LH and progesterone and the magnitude of LH rise are independent predictors of the total number of oocytes and mature oocytes retrieved. WHAT IS KNOWN ALREADY: Despite multiple follicular development in high responders, oocyte retrieval after a GnRHa trigger in a small subset of patients fails to obtain a substantial number of total oocytes or mature oocytes...
January 2013: Human Reproduction
https://www.readbyqxmd.com/read/22936978/a-novel-porcine-circovirus-like-agent-p1-is-associated-with-wasting-syndromes-in-pigs
#14
Libin Wen, Kongwang He, Qi Xiao, Zhengyu Yu, Aihua Mao, Yanxiu Ni, Xuehan Zhang, Bin Li, Xiaomin Wang, Rongli Guo, Junming Zhou, Lixin Lv, Jieyuan Jiang
A novel porcine pathogen tentatively named P1, which was obtained from the sera of the pigs exhibiting clinical signs of postweaning multisystemic wasting syndrome (PMWS) experimentally caused the classical clinic signs and pathologic lesions of the disease in pigs by direct in vivo injection with P1 DNA plasmids. Twenty colostrum-fed (CF) pigs that were free of PCV2 and P1 at 1 month of age were randomly designated equally to two groups. Group 1 pigs were each injected with 400 µg of the cloned P1 plasmid DNA into the superficial inguinal lymph nodes and Group 2 were injected with same amount of the empty pSK vector DNA and served as controls...
2012: PloS One
https://www.readbyqxmd.com/read/22843475/primary-amenorrhea-due-to-empty-sella-an-underestimated-entity
#15
Nitin Dange, Rakesh Redhu, Juhi Kawale, Amit Mahore
We report a 16-year-old girl who had stunted growth and primary amenorrhea presenting with headache and vomiting. MRI of brain showed posterior fossa dermoid cyst with hydrocephalus and empty sella. Growth hormone (GH), Leutinizing hormone (LH) and Follicular stimulating hormone (FSH) were grossly reduced on endocrinological work-up. She underwent suboccipital midline craniectomy and complete excision of dermoid cyst .She had no additional deficit after the surgery. She had menarche six months after the surgery and developed adequate secondary sexual characters, however her height remains subnormal at follow-up after 2 years as compared to age matched controls...
2012: Turkish Neurosurgery
https://www.readbyqxmd.com/read/22769734/can-in%C3%A2-vitro-fertilization-cycles-be-salvaged-by-repeat-administration-of%C3%A2-intramuscular-human-chorionic-gonadotropin-the-day-after-failed-injection
#16
David E Reichman, Eleni Greenwood, Laura Meyer, Isaac Kligman, Zev Rosenwaks
OBJECTIVE: To investigate the incidence of negative serum hCG level after initial IM trigger injection and whether such cycles can be salvaged through repeat administration of IM hCG. DESIGN: Retrospective cohort study. SETTING: Academic medical center. PATIENT(S): All patients undergoing IVF at the Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, from January 1, 2005 to November 1, 2011...
September 2012: Fertility and Sterility
https://www.readbyqxmd.com/read/22608311/rescue-human-chorionic-gonadotropin-for-false-empty-follicle-syndrome-optimism-for-successful-pregnancy-outcome
#17
Joseph O'Brien Doyle, Jill Amanda Attaman, Aaron Kyle Styer, Mary Elizabeth Sabatini, John Christopher Petrozza, Thomas Louis Toth
OBJECTIVE: To describe two cases of successful pregnancy after a rescue course of hCG in the setting of false empty follicle syndrome. DESIGN: Case report. SETTING: Academic medical center. PATIENT(S): Two patients undergoing ultrasound-guided oocyte retrieval with failure to obtain oocytes during oocyte retrieval. INTERVENTION(S): Rescue course of hCG with second oocyte retrieval 35 hours later...
August 2012: Fertility and Sterility
https://www.readbyqxmd.com/read/22585636/unique-patient-issues-early-interventions-and-management
#18
REVIEW
Catherine Combelles
Patient cases that present with recurring fertilization failure or complete abnormality in either the oocytes or sperm before fertilization are uncommon, yet they are devastating. This review presents several such instances, including oocyte maturation blocks, empty follicle syndrome, oocyte activation failures, defects in sperm phospholipase C isoform ζ, sperm structural anomalies, spontaneous oocyte activation, and unexplained cases. Diagnostic efforts have not only provided insight into possible etiologies but also have helped manage such challenging cases...
June 2012: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/22357773/empty-follicle-syndrome-successful-treatment-in-a-recurrent-case-and-review-of-the-literature
#19
REVIEW
R Beck-Fruchter, A Weiss, M Lavee, Y Geslevich, E Shalev
Empty follicle syndrome is a condition in which no oocytes are retrieved after an apparently adequate ovarian response to stimulation and meticulous follicular aspiration. It is a rare condition of obscure etiology. A patient with primary infertility who underwent seven assisted reproductive technique cycles is described. In spite of a satisfactory ovarian response, aspiration yielded no oocytes in four cycles and 1-4 low quality oocytes in three cycles. In the index treatment cycle, ovulation was triggered using GnRH agonist 40 h prior to ovum pickup and hCG was added 6 h after the first trigger...
May 2012: Human Reproduction
https://www.readbyqxmd.com/read/22346083/recurrent-genuine-empty-follicle-syndrome
#20
Mp Smisha, Kundavi Sankar, Betty Thomas, Thangam R Varma
Failure to aspirate oocytes after ovarian stimulation for an in vitro fertilization cycle, after confirming normal folliculogenesis and steroidogenesis occurs in about 0.2-7% of the cycles. This condition is known as empty follicle syndrome. Most of the time, it may be due to human or pharmacological error, but rarely there is an entity called genuine empty follicle syndrome where no known cause can be identified.
September 2011: Journal of Human Reproductive Sciences
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