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https://www.readbyqxmd.com/read/29655877/endocrine-and-haemodynamic-changes-in-resistant-hypertension-and-blood-pressure-responses-to-spironolactone-or-amiloride-the-pathway-2-mechanisms-substudies
#1
Bryan Williams, Thomas M MacDonald, Steve V Morant, David J Webb, Peter Sever, Gordon T McInnes, Ian Ford, J Kennedy Cruickshank, Mark J Caulfield, Sandosh Padmanabhan, Isla S Mackenzie, Jackie Salsbury, Morris J Brown
BACKGROUND: In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs. We did three substudies to assess the mechanisms underlying this superiority and the pathogenesis of resistant hypertension. METHODS: PATHWAY-2 was a randomised, double-blind crossover trial done at 14 UK primary and secondary care sites in 314 patients with resistant hypertension. Patients were given 12 weeks of once daily treatment with each of placebo, spironolactone 25-50 mg, bisoprolol 5-10 mg, and doxazosin 4-8 mg and the change in home systolic blood pressure was assessed as the primary outcome...
April 11, 2018: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29651816/theoretical-and-hands-on-guidance-from-dental-hygienists-promotes-good-oral-health-in-elderly-people-living-in-nursing-homes-a-pilot-study
#2
B Seleskog, L Lindqvist, I Wårdh, A Engström, I von Bültzingslöwen
OBJECTIVES: Oral health in nursing homes for elderly is often unsatisfactory, and oral health education to nursing staff has not shown sufficient results why there is need for novel approaches. The aim of the study was to trial a new oral healthcare educational programme and to evaluate the effects on residents' oral health. In addition, attitudes among the nursing staff in the intervention nursing home were explored. METHODS: In a controlled clinical trial, two comparable nursing homes were randomly assigned for intervention or control...
April 12, 2018: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/29650130/effects-of-single-session-group-mantra-meditation-on-salivary-immunoglobulin-a-and-affective-state-a-psychoneuroimmunology-viewpoint
#3
Fatemeh Torkamani, Alireza Aghayousefi, Ahmad Alipour, Mohammad Nami
OBJECTIVES: Based on existing psychoneuroimmunological insights, the present study aimed at investigating possible effects of a single-session group mantra-meditation on salivary immunoglobulin A (s-IgA) and affective states. MATERIALS AND METHODS: A controlled pretest-posttest study enrolled 30 healthy women (mean age 44 ± 3 years) through a multi-stage random sampling method from yoga clubs in Shiraz (Feb-Dec, 2016). Subjects were randomly assigned to experimental (n = 15) and control (n = 15) groups...
March 2018: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/29649939/participation-patterns-of-preschool-children-with-intellectual-developmental-disabilities
#4
Yafit Gilboa, Reut Fuchs
We aim to examine the pattern of participation of children with intellectual developmental disabilities (IDD) or global developmental delay (GDD) in comparison with typically developing preschoolers. In addition, to identify environmental and personal factors associated with their participation, 20 children with mild to moderate GDD or IDD, and 24 age- and gender-matched controls, aged 3 to 6 years, were assessed using the Assessment of Preschool Children's Participation and the Environmental Restriction Questionnaire...
April 1, 2018: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/29649897/an-investigation-of-youth-assets-and-physical-activity-and-bmi-using-a-longitudinal-cohort-design
#5
Roy F Oman, Kristen Clements-Nolle, Minggen Lu, Taylor Lensch
PURPOSE: Substantial research has demonstrated that assets (eg, family communication, school connectedness) protect youth from participation in numerous risk behaviors. However, very few studies have explored the relationship between assets and positive health behaviors. This study investigated prospective associations among assets and physical activity (PA) and body mass index (BMI). DESIGN: Longitudinal design with 5 waves of data collected annually over a 4-year period...
January 1, 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29642868/adaptation-of-an-evidence-based-postpartum-depression-intervention-feasibility-and-acceptability-of-mothers-and-babies-1-on-1
#6
S Darius Tandon, Julie A Leis, Erin A Ward, Hannah Snyder, Tamar Mendelson, Deborah F Perry, Mya Carter, Jaime Hamil, Huynh-Nhu Le
BACKGROUND: Mothers and Babies (MB) is a cognitive-behavioral intervention with demonstrated efficacy in reducing depressive symptoms and preventing depressive episodes among perinatal women when delivered in a group format by mental health professionals. Study aims were to describe the adaptation of MB into a 1-on-1 modality (MB 1-on-1) and provide data on the adapted intervention's acceptability and feasibility. METHODS: Seventy-five home visitors trained on MB 1-on-1 delivered the 15-session intervention to 1-2 clients...
April 11, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29629923/organizational-processes-and-patient-experiences-in-the-patient-centered-medical-home
#7
Jaya Aysola, Marilyn M Schapira, Hairong Huo, Rachel M Werner
BACKGROUND: There is increasing emphasis on the use of patient-reported experience data to assess practice performance, particularly in the setting of patient-centered medical homes. Yet we lack understanding of what organizational processes relate to patient experiences. OBJECTIVE: Examine associations between organizational processes practices adopt to become PCMH and patient experiences with care. RESEARCH DESIGN: We analyzed visit data from patients (n=8356) at adult primary care practices (n=22) in a large health system...
April 6, 2018: Medical Care
https://www.readbyqxmd.com/read/29629506/what-influences-parental-engagement-in-early-intervention-parent-program-and-community-predictors-of-enrolment-retention-and-involvement
#8
Naomi J Hackworth, Jan Matthews, Elizabeth M Westrupp, Cattram Nguyen, Tracey Phan, Amanda Scicluna, Warren Cann, Donna Bethelsen, Shannon K Bennetts, Jan M Nicholson
Poor participant engagement undermines individual and public health benefits of early intervention programs. This study assessed the extent to which three types of engagement (participant enrolment, retention and involvement) were influenced by individual, program and contextual factors. Data were from a cluster randomised controlled trial (N = 1447) of a community-based parenting program, delivered at two levels of intensity (group sessions with and without individualised home coaching) conducted in Victoria, Australia...
April 9, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29627621/the-optima-study-buprenorphine-naloxone-and-methadone-models-of-care-for-the-treatment-of-prescription-opioid-use-disorder-study-design-and-rationale
#9
M Eugenia Socias, Keith Ahamad, Bernard Le Foll, Ron Lim, Julie Bruneau, Benedikt Fischer, T Cameron Wild, Evan Wood, Didier Jutras-Aswad
BACKGROUND: Rates of non-medical use of opioids, and opioid use disorders (OUD) have been rising throughout North America. Methadone and buprenorphine/naloxone are the recommended first-line treatment options for OUD in Canada. Most studies to date have been conducted among heroin users, in controlled settings, and using similar strict dosing schedules (i.e., daily witnessed ingestion) despite buprenorphine/naloxone's superior safety profile, which allows a more flexible take-home dosing schedule...
April 5, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29625358/the-role-of-travel-distance-and-price-promotions-in-tobacco-product-purchase-quantity
#10
Nathan J Doogan, Sarah Cooper, Amanda J Quisenberry, Theodore M Brasky, Christopher R Browning, Elizabeth G Klein, Alice Hinton, Haikady N Nagaraja, Wenna Xi, Mary Ellen Wewers
INTRODUCTION: Rural Americans are particularly vulnerable to tobacco price reducing promotions are known to be directed to and used by vulnerable populations. Tobacco purchasing decisions, such as unit quantity purchased, may vary by rurality, by price promotion use, and possibly by the interaction between the two. Purchase decisions are likely to affect tobacco use behavior. Therefore, explanation of variation in tobacco purchase quantity by factors associated with rural vulnerability and factors that fall under the regulatory scope of the Tobacco Control Act (TCA) of 2009 could be of value to regulatory proposals intended to equitably benefit public health...
April 3, 2018: Health & Place
https://www.readbyqxmd.com/read/29623255/use-of-pre-hospital-medication-in-children-presenting-with-malaria-to-the-emergency-unit-of-mulago-hospital-uganda-a-descriptive-study
#11
Victor S Tumukunde, Elizabeth Kiboneka, Chandy C John, Robert O Opoka, Richard Idro
Background: Initiation of specific antimalarial treatment within 24 hrs of fever onset at home and before presentation to the hospital is one of the strategies to reduce mortality from malaria in sub-Saharan Africa. In order to determine whether this strategy is being implemented we describe the use and factors associated with the use of pre-hospital medications among children admitted with malaria in one of the tertiary hospitals in Uganda. Materials and methods: Use of pre-hospital medications was assessed in 205 children aged 6-59 months and diagnosed with malaria at admission in Mulago hospital...
July 2017: MalariaWorld Journal
https://www.readbyqxmd.com/read/29623096/drinking-water-supply-sanitation-and-hygiene-promotion-interventions-in-two-slum-communities-in-central-uganda
#12
David Musoke, Rawlance Ndejjo, Abdullah Ali Halage, Simon Kasasa, John C Ssempebwa, David O Carpenter
Poor water, sanitation, and hygiene (WASH) continue to contribute to the high prevalence of diarrhoeal diseases in low-income countries such as Uganda particularly in slums. We implemented a 3-year WASH project in two urban slums in Uganda with a focus on safe drinking water and improvement in sanitation. The project implemented community and school interventions in addition to capacity building initiatives. Community interventions included home improvement campaigns, clean-up exercises, water quality assessment, promotion of drinking safe water through household point-of-use chlorination, promotion of hand washing, and support towards solid waste management...
2018: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/29621908/cost-utility-analysis-on-telemonitoring-of-users-with-pacemakers-the-poniente-study
#13
Antonio Lopez-Villegas, Daniel Catalan-Matamoros, Emilio Robles-Musso, Rafael Bautista-Mesa, Salvador Peiro
Introduction Few studies have confirmed the cost-saving of telemonitoring of users with pacemakers (PMs). The purpose of this controlled, non-randomised, non-masked clinical trial was to perform an economic assessment of telemonitoring (TM) of users with PMs and check whether TM offers a cost-utility alternative to conventional follow-up in hospital. Methods Eighty-two patients implanted with an internet-based transmission PM were selected to receive either conventional follow-up in hospital ( n = 52) or TM ( n = 30) from their homes...
January 1, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29621888/asthma-knowledge-care-and-outcome-during-pregnancy-the-qakcop-study
#14
Wanis H Ibrahim, Fatima Rasul, Mushtaq Ahmad, Abeer S Bajwa, Laith I Alamlih, Anam M El Arabi, Mujahed M Dauleh, Ibrahim Y Abubeker, Muhammed U Khan, Tayseer S Ibrahim, Azdin A Ibrahim
Asthma is the most common chronic medical condition affecting pregnancy. Optimizing asthma management in pregnancy is paramount for the well-being of both the mother and the baby. The primary objectives of this study were to assess patient's knowledge about asthma, the level of asthma care, and fetal and maternal outcomes among pregnant asthmatic women in this wealthy country with tremendous improvement in maternal and fetal health care. The secondary objective was to identify barriers to asthma control. This was a cross-sectional, face-to-face, prospective study of 80 pregnant women with physician-diagnosed asthma...
January 1, 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29620961/building-a-medicaid-ambulatory-complex-care-program-within-an-urban-medical-home
#15
Laura D Sander, Michael Albert, Nkem Okeke, Steven Kravet, Katherine Rediger, Sarah Johnson Conway, Maura J McGuire
Five percent of Medicaid patients account for 50% of total costs. Preventable costs are often incurred by patients with complex medical, behavioral, and social needs who disproportionately utilize acute care services. Evidence for design, implementation, and evaluation of complex care programs in the urban Medicaid population is lacking. The article provides a description of a complex care program (CCP), challenges, and early outcomes based on a pre-post evaluation. The CCP was located within an existing urban medical home...
April 5, 2018: Population Health Management
https://www.readbyqxmd.com/read/29618925/can-community-care-workers-deliver-a-falls-prevention-exercise-program-a-feasibility-study
#16
Elissa Burton, Gill Lewin, Hilary O'Connell, Mark Petrich, Eileen Boyle, Keith D Hill
Background: Almost half of older people receiving community care fall each year and this rate has not improved in the last decade. Falls prevention programs targeted at this group are uncommon, and expensively delivered by university trained allied health professionals. Purpose: To investigate the feasibility of community care workers delivering a falls prevention exercise program to older clients, at low or medium risk of falling, as part of an existing service provision...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29618331/design-implementation-and-evaluation-of-a-web-based-computer-tailored-intervention-to-prevent-binge-drinking-in-adolescents-study-protocol
#17
Marta Lima-Serrano, José Manuel Martínez-Montilla, Joaquín S Lima-Rodríguez, Liesbeth Mercken, Hein de Vries
BACKGROUND: Binge-drinking in adolescents is a highly prevalent healthcare problem that associates physical and mental health complications with community implications. This paper describes the design, implementation and evaluation of the first web-based computer tailored intervention aimed at the prevention of binge drinking in Spanish adolescents. METHODS: The Alerta Alcohol program is based on the I-Change Model. First, feedback from focus and Delphi groups are used for cultural adaptation and to obtain further information on the items to be included on the program...
April 4, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29617776/counseling-received-by-adolescents-undergoing-voluntary-medical-male-circumcision-moving-toward-age-equitable-comprehensive-human-immunodeficiency-virus-prevention-measures
#18
Michelle R Kaufman, Eshan U Patel, Kim H Dam, Zoe R Packman, Lynn M Van Lith, Karin Hatzold, Arik V Marcell, Webster Mavhu, Catherine Kahabuka, Lusanda Mahlasela, Emmanuel Njeuhmeli, Kim Seifert Ahanda, Getrude Ncube, Gissenge Lija, Collen Bonnecwe, Aaron A R Tobian
Background: The minimum package of voluntary medical male circumcision (VMMC) services, as defined by the World Health Organization, includes human immunodeficiency virus (HIV) testing, HIV prevention counseling, screening/treatment for sexually transmitted infections, condom promotion, and the VMMC procedure. The current study aimed to assess whether adolescents received these key elements. Methods: Quantitative surveys were conducted among male adolescents aged 10-19 years (n = 1293) seeking VMMC in South Africa, Tanzania, and Zimbabwe...
April 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29616653/accessibility-of-cesarean-deliveries-in-benin
#19
V Mongbo, J Saïzonou, G Sopoh, C Sossa-Jérôme, E M Ouendo, I Godin
To be used effectively, emergency obstetric and neonatal care must be available and accessible. This study sought to measure the accessibility of cesarean deliveries in Benin. Cross-sectional study of randomly selected women in each of the 12 obstetrics departments in Benin. Geographical accessibility was measured by estimating the distance between the parturientes residence and the hospital. Financial accessibility was the average direct cost of the cesarean delivery -the sum of medical and non-medical costs...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29616428/differences-in-health-related-quality-of-life-by-academic-performance-in-children-of-the-city-of-cordoba-argentina
#20
Emilse Degoy, Silvina Berra
PURPOSE: The purpose of the study was to assess the differences in health-related quality of life (HRQoL) according to academic performance (AP) in children who attend public schools in the city of Cordoba, Argentina. METHODS: Cross-sectional study carried out in a sample of 494 children aged 9-12 years (mean = 9.5; standard deviation [SD] = 0.65; IQR 1) who attended 4th grade of public schools in the city of Córdoba, Argentina in 2014. HRQoL was assessed by self-administration of the KIDSCREEN-52 child version in classroom...
April 3, 2018: Quality of Life Research
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