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https://www.readbyqxmd.com/read/27908547/high-dietary-choline-and-betaine-intake-is-associated-with-low-insulin-resistance-in-the-newfoundland-population
#1
Xiang Gao, Yongbo Wang, Guang Sun
OBJECTIVE: Dietary betaine supplement could ameliorate insulin resistance (IR) in animals, but no data are available for choline. Reports on humans are rare. The aim of this study was to investigate the association between dietary choline and betaine intake and IR in humans. METHODS: We assessed 2394 adults from the CODING (Complex Diseases in the Newfoundland population: Environment and Genetics) study. Intake of dietary choline and betaine was evaluated from the Willett Food Frequency Questionnaire...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27906041/implementation-of-the-better-2-program-a-qualitative-study-exploring-barriers-and-facilitators-of-a-novel-way-to-improve-chronic-disease-prevention-and-screening-in-primary-care
#2
Nicolette Sopcak, Carolina Aguilar, Mary Ann O'Brien, Candace Nykiforuk, Kris Aubrey-Bassler, Richard Cullen, Eva Grunfeld, Donna Patricia Manca
BACKGROUND: BETTER (Building on Existing Tools to Improve Chronic Disease Prevention and Screening in Primary Care) is a patient-based intervention to improve chronic disease prevention and screening (CDPS) for cardiovascular disease, diabetes, cancer, and associated lifestyle factors in patients aged 40 to 65. The key component of BETTER is a prevention practitioner (PP), a health care professional with specialized skills in CDPS who meets with patients to develop a personalized prevention prescription, using the BETTER toolkit and Brief Action Planning...
December 1, 2016: Implementation Science: IS
https://www.readbyqxmd.com/read/27865756/association-of-insulin-dosage-with-mortality-or-major-adverse-cardiovascular-events-a-retrospective-cohort-study
#3
John-Michael Gamble, Eugene Chibrikov, Laurie K Twells, William K Midodzi, Stephanie W Young, Don MacDonald, Sumit R Majumdar
BACKGROUND: Existing studies have shown conflicting evidence regarding the safety of exogenous insulin therapy in patients with type 2 diabetes. In particular, observational studies have reported an increased risk of death and cardiovascular disease among users of higher versus lower doses of insulin. We aimed to quantify the association between increasing dosage of insulin exposure and death and cardiovascular events, while taking into account time-dependent confounding and mediation that might have biased previous studies...
November 16, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27797700/age-at-first-drink-experiences-of-drunkenness-and-alcohol-related-problems-in-canadian-youth-is-early-onset-bad-if-you-are-a-moderate-drinker
#4
Mark Asbridge, Jenny Cartwright, Kevin Wilson, Donald Langille
OBJECTIVE: This article examines early age at first drink (AFD) (14 years and younger) and alcohol-related problems, with a focus on experiences of drunkenness. It challenges the assumption that all early AFD is harmful by investigating whether early drinkers who typically consume alcohol in moderation experience minimal problems or harms. METHOD: Participants were drawn from the 2012 Student Drug Use Survey in Canada's Atlantic Provinces of New Brunswick, Nova Scotia, and Newfoundland and Labrador, an anonymous cross-sectional survey of high school students (ages 15-19 years)...
November 2016: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27793212/the-newfoundland-and-labrador-bariatric-surgery-cohort-study-rational-and-study-protocol
#5
Laurie K Twells, Deborah M Gregory, William K Midodzi, Carla Dillon, Christopher S Kovacs, Don MacDonald, Kendra K Lester, David Pace, Chris Smith, Darrell Boone, Raleen Murphy
BACKGROUND: In Canada, there has been a disproportionate increase in adults with Class II (BMI 35.0-39.9 kg/m(2)) or Class III obesity (BMI ≥ 40 kg/m(2)) affecting 9 % of Canadians with increases projected. Individuals affected by severe obesity (BMI ≥ 35) are at increased risk of high blood pressure, cardiovascular disease, diabetes, cancer, impaired quality of life, and premature mortality. Bariatric surgery is the most effective treatment for severe obesity. Laparoscopic sleeve gastrectomy (LSG), a relatively new type of bariatric surgery, is growing in popularity as a treatment...
October 28, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27790632/infodemiological-data-of-high-school-drop-out-related-web-searches-in-canada-correlating-with-real-world-statistical-data-in-the-period-2004-2012
#6
Anna Siri, Hicham Khabbache, Ali Al-Jafar, Mariano Martini, Francesco Brigo, Nicola Luigi Bragazzi
The present data article describes high-school drop-out related web activities in Canada, from 2004 to 2012, obtained mining Google Trends (GT), using high-school drop-out as key-word. The searches volumes were processed, correlated and cross-correlated with statistical data obtained at national and province level and broken down for gender. Further, an autoregressive moving-average (ARMA) model was used to model the GT-generated data. From a qualitative point of view, GT-generated relative search volumes (RSVs) reflect the decrease in drop-out rate...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27775557/chemical-analysis-of-extracts-from-newfoundland-berries-and-potential-neuroprotective-effects
#7
Mohammad Z Hossain, Emily Shea, Mohsen Daneshtalab, John T Weber
Various species of berries have been reported to contain several polyphenolic compounds, such as anthocyanins and flavonols, which are known to possess high antioxidant activity and may be beneficial for human health. To our knowledge, a thorough chemical analysis of polyphenolics in species of these plants native to Newfoundland, Canada has not been conducted. The primary objective of this study was to determine the polyphenolic compounds present in commercial extracts from Newfoundland berries, which included blueberries (V...
October 19, 2016: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/27774297/driving-forces-behind-the-evolution-of-the-aleutian-mink-disease-parvovirus-in-the-context-of-intensive-farming
#8
Marta Canuti, Kimberly E O'Leary, Bruce D Hunter, Grant Spearman, Davor Ojkic, Hugh G Whitney, Andrew S Lang
Aleutian mink disease virus (AMDV) causes plasmacytosis, an immune complex-associated syndrome that affects wild and farmed mink. The virus can also infect other small mammals (e.g., ferrets, skunks, ermines, and raccoons), but the disease in these hosts has been studied less. In 2007, a mink plasmacytosis outbreak began on the Island of Newfoundland, and the virus has been endemic in farms since then. In this study, we evaluated the molecular epidemiology of AMDV in farmed and wild animals of Newfoundland since before the beginning of the outbreak and investigated the epidemic in a global context by studying AMDV worldwide, thereby examining its diffusion and phylogeography...
January 2016: Virus Evolution
https://www.readbyqxmd.com/read/27771096/low-plastic-ingestion-rate-in-atlantic-cod-gadus-morhua-from-newfoundland-destined-for-human-consumption-collected-through-citizen-science-methods
#9
Max Liboiron, France Liboiron, Emily Wells, Natalie Richárd, Alexander Zahara, Charles Mather, Hillary Bradshaw, Judyannet Murichi
Marine microplastics are a contaminant of concern because their small size allows ingestion by a wide range of marine life. Using citizen science during the Newfoundland recreational cod fishery, we sampled 205 Atlantic cod (Gadus morhua) destined for human consumption and found that 5 had eaten plastic, an ingestion prevalence rate of 2.4%. This ingestion rate for Atlantic cod is the second lowest recorded rate in the reviewed published literature (the lowest is 1.4%), and the lowest for any fish in the North Atlantic...
October 19, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27738573/emergency-medicine-in-remote-regions
#10
Tia Renouf, Megan Pollard
Rural and remote places like Sable Island (Nova Scotia) or François (Newfoundland) pose a challenge in delivering both health care and appropriate education that today's learners need to practice in a rural setting. This education can be difficult to deliver to students far from academic centers. This is especially true for learners and practitioners at offshore locations like ships, oil installations, or in the air when patients are transported via fixed wing aircraft or helicopter. The following editorial provides a snapshot of the setting and the challenges faced while working as a physician on a ship, in remote regions...
September 9, 2016: Curēus
https://www.readbyqxmd.com/read/27737686/effectiveness-of-a-pharmacist-driven-intervention-in-copd-epic-study-protocol-for-a-randomized-controlled-trial
#11
Erin Davis, Carlo Marra, John-Michael Gamble, Jamie Farrell, Joe Lockyer, J Mark FitzGerald, Waseem Abu-Ashour, Charlie Gillis, John Hawboldt
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) are often nonadherent with medications and have poor inhaler technique. Community pharmacists can help to improve health-related quality of life and overall outcomes in patients with COPD. We aim to measure the effectiveness of a systematic, pharmacist-driven intervention on patients with diagnosed COPD. METHODS/DESIGN: This pragmatic, parallel-group, cluster randomized controlled trial is designed to determine the effectiveness of a multifactorial, pharmacist-led intervention on medication adherence, inhaler technique, health-related quality of life, health care resource utilization including COPD exacerbations, and use of medications...
October 13, 2016: Trials
https://www.readbyqxmd.com/read/27735821/hospital-and-intensive-care-unit-length-of-stay-for-injury-admissions-a-pan-canadian-cohort-study
#12
Lynne Moore, Henry Thomas Stelfox, David Evans, Sayed Morad Hameed, Natalie L Yanchar, Richard Simons, John Kortbeek, Gilles Bourgeois, Julien Clément, François Lauzier, Alexis F Turgeon
OBJECTIVE: To assess the variation in hospital and intensive care unit (ICU) length of stay (LOS) for injury admissions across Canadian provinces and to evaluate the relative contribution of patient case mix and treatment-related factors (intensity of care, complications, and discharge delays) to explaining observed variations. BACKGROUND: Identifying unjustified interprovider variations in resource use and the determinants of such variations is an important step towards optimizing health care...
October 4, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27716923/depth-and-temperature-associations-of-haddock-melanogrammus-aeglefinus-off-southern-newfoundland
#13
R Rogers, S Rowe, M J Morgan
Using data collected as part of offshore surveys conducted during 1972-2013, haddock Melanogrammus aeglefinus association patterns with depth and temperature in southern Newfoundland waters, the northern extremity of the species' range in the western Atlantic Ocean, were quantified. They were typically concentrated in the deep warm waters along the narrow shelf slope in North-west Atlantic Fisheries Organization Divisions 3O and 3P with individuals moving seasonally into the shallow waters of the banks as they warmed...
September 8, 2016: Journal of Fish Biology
https://www.readbyqxmd.com/read/27696385/evaluation-of-a-population-based-approach-to-familial-colorectal-cancer
#14
P S Parfrey, E Dicks, O Parfrey, P J McNicholas, H Noseworthy, M O Woods, C Negriin, J Green
As Newfoundland has the highest rate of familial CRC in the world, we started a population-based clinic to provide colonoscopic and Lynch syndrome (LS) screening recommendations to families of CRC patients based on family risk. Of 1091 incident patients 52% provided a family history. Seventy-two percent of families were at low or intermediate-low risk of CRC and colonoscopic screening recommendations were provided by letter. Twenty eight per cent were at high and intermediate-high risk and were referred to the genetic counsellor, but only 30% (N = 48) were interviewed by study end...
October 3, 2016: Clinical Genetics
https://www.readbyqxmd.com/read/27668118/impact-of-body-mass-index-on-short-term-outcomes-in-patients-undergoing-percutaneous-coronary-intervention-in-newfoundland-and-labrador-canada
#15
Anne B Gregory, Kendra K Lester, Deborah M Gregory, Laurie K Twells, William K Midodzi, Neil J Pearce
Background and Aim. Obesity (BMI ≥ 30 kg/m(2)) is associated with advanced cardiovascular disease requiring procedures such as percutaneous coronary intervention (PCI). Studies report better outcomes in obese patients having these procedures but results are conflicting or inconsistent. Newfoundland and Labrador (NL) has the highest rate of obesity in Canada. The aim of the study was to examine the relationship between BMI and vascular and nonvascular complications in patients undergoing PCI in NL. Methods...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27663786/a-model-for-sea-lice-lepeophtheirus-salmonis-dynamics-in-a-seasonally-changing-environment
#16
Matthew A Rittenhouse, Crawford W Revie, Amy Hurford
Sea lice (Lepeophtheirus salmonis) are a significant source of monetary losses on salmon farms. Sea lice exhibit temperature-dependent development rates and salinity-dependent mortality, but to date no deterministic models have incorporated these seasonally varying factors. To understand how environmental variation and life history characteristics affect sea lice abundance, we derive a delay differential equation model and parameterize the model with environmental data from British Columbia and southern Newfoundland...
September 2016: Epidemics
https://www.readbyqxmd.com/read/27650806/provincial-variation-of-cochlear-implantation-surgical-volumes-and-cost-in-canada
#17
Matthew G Crowson, Joseph M Chen, Debara Tucci
OBJECTIVES: To investigate provincial cochlear implantation (CI) annual volume and cost trends. STUDY DESIGN: Database analysis. SETTING: National surgical volume and cost database. SUBJECTS AND METHODS: Aggregate-level provincial CI volumes and cost data for adult and pediatric CI surgery from 2005 to 2014 were obtained from the Canadian Institute for Health Information. Population-level aging forecast estimates were obtained from the Ontario Ministry of Finance and Statistics Canada...
September 20, 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/27638980/the-impact-of-maternal-obesity-on-breastfeeding
#18
Naila Ramji, James Quinlan, Phil Murphy, Joan M G Crane
OBJECTIVE: To compare the rate of any breastfeeding at the time of postpartum hospital discharge between obese women (BMI ≥ 30.00 kg/m(2)) and women with a normal BMI (18.50 to 24.99 kg/m(2)). METHODS: We conducted a retrospective cohort study of women with live, singleton pregnancies who delivered in St. John's, Newfoundland and Labrador between 2002 and 2011, using data from the Newfoundland and Labrador provincial perinatal registry. The primary outcome was any breastfeeding at the time of discharge from hospital...
August 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27609235/a-study-of-wrecked-dovekies-alle-alle-in-the-western-north-atlantic-highlights-the-importance-of-using-standardized-methods-to-quantify-plastic-ingestion
#19
Stephanie Avery-Gomm, Michelle Valliant, Carley R Schacter, Katherine F Robbins, Max Liboiron, Pierre-Yves Daoust, Lorena M Rios, Ian L Jones
Quantification of plastic ingestion across a range of seabirds is required to assess the prevalence of plastics in marine food webs. We quantified plastic ingestion in beached Dovekies (Alle alle), following a wreck in Newfoundland, Canada. Of 171 birds, 30.4% had ingested plastic (mean 0.81±0.30 SE pieces per bird, mass 0.005±0.002 SE g per bird). Most plastics were fragments of polyethylene and polypropylene. Surprisingly, 37% were burned or melted, indicating a previously unreported source of ingested plastics (incinerated waste)...
September 5, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27607331/whole-body-element-composition-of-atlantic-salmon-salmo-salar-influenced-by-migration-direction-and-life-stage-in-three-distinct-populations
#20
J D Ebel, S J Leroux, M J Robertson, J B Dempson
Body-element content was measured for three life stages of wild Atlantic salmon Salmo salar from three distinct Newfoundland populations as individuals crossed between freshwater and marine ecosystems. Life stage explained most of the variation in observed body-element concentration whereas river of capture explained very little variation. Element composition of downstream migrating post-spawn adults (i.e. kelts) and juvenile smolts were similar and the composition of these two life stages strongly differed from adults migrating upstream to spawn...
September 8, 2016: Journal of Fish Biology
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