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REVIEW
Poulami Goswami, Kanchan Sharma, Niladri Maiti, Sweta Yadav, Vartika Verma, Rahul Puthenkandathil
Ozone is utilized in dentistry as ozonated oils, ozonated water, and gaseous ozone. The application of ozone in all specialties of dentistry has been demonstrated to be biocompatible. It has been demonstrated to encourage the remineralization of recently carious teeth, and it is utilized in dental caries and intracanal irrigants in endodontic treatment. Herpes virus infection, avascular osteonecrosis of the jaw, and alveolitis have all been treated with it. It can be applied as a supplement in the surgical and ongoing stages of periodontal disease and also hinders plaque formation...
February 2024: Journal of Pharmacy & Bioallied Sciences
#22
JOURNAL ARTICLE
Ying Zhou, Ning Zhao, Hongyuan Huang, Qingxiang Li, Chuanbin Guo, Yuxing Guo
Herpes zoster of trigeminal nerve was a common skin disease caused by varicella-zoster virus infection. Simple involvement of the third branch of trigeminal nerve was rare, and so were oral complications such as pulpitis, periodontitis, spontaneous tooth loss, bone necrosis, etc. This article presented a case of herpes zoster on the third branch of the left trigeminal nerve complicated with left mandibular osteonecrosis. We reported the case of a 64-year-old man with sudden pain in the left half of the tongue 1 month ago, and then herpes on the left facial skin appeared following with acute pain...
April 18, 2024: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
#23
JOURNAL ARTICLE
Jiaqi Shi, Li Chen, Xu Wang, Xin Ma
Steroid-induced osteonecrosis of the femoral head (ONFH) is a serious complication caused by long-term or excessive use of glucocorticoids. The present study aimed to ascertain the effects of tripartite motif-containing protein 21 (TRIM21) on the process of steroid-induced ONFH and its hidden action mechanism. TRIM21 expression in dexamethasone (Dex)-treated mouse MC3T3-E1 preosteoblast cells was examined using reverse transcription-quantitative PCR and western blotting. The Cell Counting Kit-8 (CCK-8) method and lactate dehydrogenase release assay were used to respectively measure cell viability and injury...
May 2024: Experimental and Therapeutic Medicine
#24
JOURNAL ARTICLE
Fumihiro Yoshimura, Kenichiro Doi, Koichi Kinoshita, Hajime Seo, Taiki Matsunaga, Takuaki Yamamoto
Coronavirus disease 2019 is known to cause severe acute respiratory syndrome, and serious cases need to be treated with corticosteroids. Herein, we report an 87-year-old woman who developed bilateral osteonecrosis of the femoral head after corticosteroid treatment for coronavirus disease 2019-related pneumonia. Sixteen months after treatment, she developed right hip pain without any evidence of trauma. A diagnosis of bilateral osteonecrosis of the femoral head was made based on sclerotic bands on plain radiographs and low-signal bands on T1-weighted magnetic resonance images...
April 8, 2024: Skeletal Radiology
#25
JOURNAL ARTICLE
Vanessa Costa de Sousa, Fátima Regina Nunes Sousa, Raquel Felipe Vasconcelos, Gisele Angelino Barreto, Conceição S Martins, Nilson Romero Dias, Sislana Costa, Maria Jennifer Chaves Bernardino, George de Almeida Silva, Nadine Linhares, Delane Gondim, Mirna Marques, Helliada Chaves, Karuza Alves, Renata Leitão, Gerly A C Brito, Maria Elenir Nobre Pinho Ribeiro, Paula Goes
To investigate de effect of PAb gel on the bone tissue of rats submitted to Bisphosphonate-related osteonecrosis of the jaws (BRONJ). Initially, 54 animals were submitted to BRONJ model by Zoledronic Acid (ZA) (0.1 mg/kg 3x/wk for 9 wk, ip), followed by the 1st upper left molar extraction at the 8th wk. After tooth removal, the animals were divided into 3 groups, ZA that received placebo gel or PAb gel that received 1% PAb gel, inside the dental alveolus. The control Group (CONTROL) received 0.1 mg/kg of 0...
April 8, 2024: Scientific Reports
#26
Hanxiao Zhu, Jingzhi Zhu, YiFei Wang, Xiaotong Xi, Keyi Wang, Yongkang Wang, Ran Ding, Hang Li
BACKGROUND: Metamycoplasma orale (M.orale), a symbiotic bacterium observed in the human oral cavity, is generally regarded as non-pathogenic to humans. Although infrequent, symptomatic infections caused by M.orale may occur in individuals with compromised humoral immunity. Accurate identification and early diagnosis of M.orale still present significant challenges due the limitations associated with conventional detection methods. Although metagenomic next-generation sequencing (mNGS) is currently widely utilized in clinical practices and exhibits a remarkable specificity and sensitivity for detecting various pathogens, its application in the diagnosis of M...
April 15, 2024: Heliyon
#27
JOURNAL ARTICLE
Peng Shang, Ying Liu, Jie Ren, Qingqing Liu, Haobo Song, Junqing Jia, Qiang Liu
This study is to probe into the meaning of serum miR-532-5p in nontraumatic osteonecrosis of the femoral head (ONFH), and a molecular mechanism of miR-532-5p in the development of nontraumatic ONFH. This study enrolled 96 patients diagnosed with nontraumatic ONFH and 96 patients with femoral neck fracture. The levels of miR-532-5p, ABL1, MMP-3, MMP-13, and cleaved-caspase3 were determined. Radiographic progression was assessed by ARCO staging system. Visual analog scale (VAS) and Harris hip score (HHS) were employed for evaluation of the symptomatic severity of nontraumatic ONFH...
2024: Open Medicine (Warsaw, Poland)
#28
JOURNAL ARTICLE
Kanako Munakata, Hidetaka Miyashita, Yuka Yamada, Tomoya Soma, Ryotaro Iwasaki, Taneaki Nakagawa, Seiji Asoda
This prospective cohort study aimed to investigate the impact of medication-related osteonecrosis of the jaw (MRONJ) on health-related quality of life (HRQOL) and oral health-related QOL (OHRQOL) and the association between the downstaging of MRONJ and OHRQOL. The HRQOL and OHRQOL of 44 patients with MRONJ were assessed using the SF-36v2 and the General Oral Health Assessment Index (GOHAI), respectively. Treatment was performed in accordance with the AAOMS position paper (2014). The SF-36v2 and GOHAI scores at the beginning of the survey were used to evaluate the impact of MRONJ on QOL...
March 19, 2024: Journal of Cranio-maxillo-facial Surgery
#29
JOURNAL ARTICLE
Lizhen Zheng, Yuanming An, Wenxue Tong, Ziyi Chen, Yaofeng Wang, Haozhi Zhang, Shi'an Zhang, Xin Chen, Weiyang Liu, Xinluan Wang, Jiankun Xu, Ling Qin
The present study aimed to establish and evaluate a preclinical model of steroid-associated osteonecrosis (SAON) in mice. Sixteen 24-week-old male C57BL/6 mice were used to establish SAON by two intraperitoneal injections of lipopolysaccharide (LPS), followed by three subcutaneous injections of methylprednisolone (MPS). Each injection was conducted on working day, with an interval of 24 h. Six cycles of injections were conducted. Additional twelve mice (age- and gender-matched) were used as normal controls...
April 4, 2024: Bone
#30
Ayoub Bouya, Azzelarab Bennis, Omar Zaddoug, Mohammed Benchakroun, Ali Zine, Salim Bouabid
INTRODUCTION: Complex dorsal metacarpophalangeal joint (MCPJ) dislocations are uncommon injuries that mainly affect the index finger and are typically caused by a fall on an outstretched hand. It is exceptional for complex MCPJ dislocation to coexist with a distal fracture of the corresponding metacarpal bone. PRESENTATION OF THE CASE: The authors report a case of a 23-year-old man presented to the emergency, with a complex dorsal metacarpophalangeal joint dislocation of the index associated with a distal metacarpal fracture confirmed by imaging...
March 18, 2024: International Journal of Surgery Case Reports
#31
JOURNAL ARTICLE
Akshar V Patel, Connor Hoge, Andrew J Stevens, Parth A Vaghani, Noah R Takacs, Gregory Cvetanovich, Hisham Awan, Ryan C Rauck
CASE: A 27-year-old woman developed capitellar osteonecrosis after long-term corticosteroid use to treat non-Hodgkin lymphoma. She underwent an osteochondral reconstruction using a lateral femoral condyle (LFC) allograft. This graft was selected because it has a similar radius of curvature to the capitellum. The patient had osseous integration, painless, near full range of motion of her elbow 6 months postoperatively and good shoulder function 1.0 year postoperatively. CONCLUSION: The LFC allograft should be considered a viable option in treating capitellar osteonecrosis...
April 1, 2024: JBJS Case Connector
#32
JOURNAL ARTICLE
Katharina Theresa Obermeier, Ina Dewenter, Yoana Malenova, Riham Fliefel, Gabriele Kaeppler, Sven Otto
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction associated with antiresorptive drugs such as bisphosphonates and denosumab. When dealing with advanced and/or multiple MRONJ lesions undergoing surgical therapy, the extent of surgery is often a topic of discussion. The aim of this study was to identify the differences in bone density in and around the MRONJ lesion before and after surgical treatment to evaluate the needed surgical extend of the modelling osteotomy. In this retrospective study 26 patients with MRONJ lesions that were surgically treated in our department were observed...
April 4, 2024: Scientific Reports
#33
JOURNAL ARTICLE
Yusuke Ayabe, Goro Motomura, Satoshi Ikemura, Ryosuke Yamaguchi, Takeshi Utsunomiya, Noriko Yamamoto, Hidenao Tanaka, Satoshi Hamai, Shinya Kawahara, Yasuharu Nakashima
BACKGROUND: This study assessed the hip survival rate and patient-reported outcome measures (PROMs) of transtrochanteric curved varus osteotomy (CVO) for osteonecrosis of the femoral head (ONFH) compared with those of conservative management. METHODS: The CVO group comprised 32 consecutive patients (39 hips) who underwent CVO for ONFH between 2000 and 2011. The conservative group consisted of 36 consecutive patients (37 hips) who were managed conservatively for at least 1 year after collapse and who had ONFH classified by the Japanese Investigation Committee of Health and Welfare as type B or C1, for which CVO is indicated...
April 2, 2024: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
#34
REVIEW
Kaikai Huang, Youyuan Wang, Yuhua Huang, Shanshan Han, Yu Yang, Pinghua Qu, Baoying Liang, Qingyu Zhen, Wenting Chen, Ying Lin
BACKGROUND: Herpes zoster (HZ) is one of the most common skin diseases caused by viruses. Facial HZ develops when the varicella-zoster virus affects the trigeminal nerve, and alveolar osteonecrosis is a rare complication. However, the exact pathogenesis of postherpetic alveolar osteonecrosis remains unclear. CASE DESCRIPTION: We encountered a patient who presented to the dermatology clinic with facial HZ and tooth exfoliation in the upper right jaw, and panoramic radiography revealed decreased bone density and poor alveolar socket healing in his right maxilla...
April 2, 2024: BMC Oral Health
#35
JOURNAL ARTICLE
Ah Reum Lim, Wonse Park, Seok Joo Moon, Min Sun Kim, Soohyeon Lee
BACKGROUND: Bone-modifying agents (BMA) are key components in the management of cancer patients with bone metastasis. Despite their clinical benefits, the use of BMA is associated with dental adverse events (AEs) including medication-related osteonecrosis of the jaw (MRONJ). This study investigated the frequency of dental surveillance before BMA treatment and the prevalence of dental AEs including MRONJ, after BMA treatment in patients with bone metastasis from breast and prostate cancer using data from the national health insurance system...
April 2, 2024: BMC Health Services Research
#36
JOURNAL ARTICLE
Cameron Bell, Alborz Feizi, Gregory R Roytman, Alim F Ramji, Steven M Tommasini, Daniel H Wiznia
BACKGROUND: Femoral head avascular necrosis (AVN), or death of femoral head tissue due to a lack of blood supply, is a leading cause of total hip replacement for non-geriatric patients. Core decompression (CD) is an effective treatment to re-establish blood flow for patients with AVN. Techniques aimed at improving its efficacy are an area of active research. We propose the use of 3D printed drill guides to accurately guide therapeutic devices for CD. METHODS: Using femur sawbones, image processing software, and 3D modeling software, we created a custom-built device with pre-determined drill trajectories and tested the feasibility of the 3D printed drill guides for CD...
April 2, 2024: 3D Printing in Medicine
#37
JOURNAL ARTICLE
Hugh J Freeman
No abstract text is available yet for this article.
May 1, 2024: European Journal of Gastroenterology & Hepatology
#38
Cheng-Ta Wu, Feng-Chih Kuo, Shih-Hsiang Yen, Po-Chun Lin, Jun-Wen Wang, Mel S Lee
No abstract text is available yet for this article.
March 29, 2024: Journal of Arthroplasty
#39
JOURNAL ARTICLE
Junichi Nakamura, Wakaba Fukushima, Wataru Ando, Shigeo Hagiwara, Yuya Kawarai, Yuki Shiko, Yohei Kawasaki, Takashi Sakai, Kazuya Ito, Yoshiya Arishima, Etsuo Chosa, Yusuke Fujimoto, Kazuo Fujiwara, Yukiharu Hasegawa, Shinya Hayashi, Takashi Imagama, Yutaka Inaba, Yasuyuki Ishibashi, Yasuhiro Ishidou, Hideya Ito, Hiroshi Ito, Juji Ito, Tetsuya Jinno, Tamon Kabata, Nobuhiro Kaku, Ayumi Kaneuji, Shunji Kishida, Seneki Kobayashi, Setsuro Komiya, Toshikazu Kubo, Tokifumi Majima, Naohiko Mashima, Masaaki Mawatari, Hidenobu Miki, Kazumasa Miyatake, Goro Motomura, Satoshi Nagoya, Hiroaki Nakamura, Yoshihide Nakamura, Ryosuke Nakanishi, Yasuharu Nakashima, Satoshi Nakasone, Takashi Nishii, Takayuki Nishiyama, Yoichi Ohta, Kenji Ohzono, Makoto Osaki, Kan Sasaki, Taisuke Seki, Takaaki Shishido, Takeshi Shoji, Akihiro Sudo, Michiaki Takagi, Daisuke Takahashi, Masaki Takao, Sakae Tanaka, Takeyuki Tanaka, Tomonori Tetsunaga, Keiichiro Ueshima, Kengo Yamamoto, Takuaki Yamamoto, Yuji Yamamoto, Takuma Yamasaki, Yuji Yasunaga, Nobuhiko Sugano
OBJECTIVES: This study documents the time elapsed from the diagnosis of osteonecrosis of the femoral head (ONFH) to surgery, exploring the factors that influence ONFH severity. DESIGN: Retrospective observational study of a nationwide database. SETTING: The Kaplan-Meier method with log-rank tests was applied to examine the period from definitive diagnosis of ONFH to surgery using any surgery as the end point. For bilateral cases, the date of the first surgery was the endpoint...
March 29, 2024: BMJ Open
#40
JOURNAL ARTICLE
Naoki Nakano Md, Toshihisa Maeda Md, Yuichi Kuroda Md, Kazunari Ishida Md, Shinya Hayashi Md, Yuichi Hoshino Md, Takehiko Matsushita Md, Ryosuke Kuroda Md, Tomoyuki Matsumoto Md
The spacer block technique is widely used in medial fixed-bearing unicompartmental knee arthroplasty (UKA) for osteoarthritis (OA) and osteonecrosis (ON), while it is still unclear if there is any difference in the extension gap between UKAs for the two conditions. To clarify the question, the data from 87 consecutive patients (OA: 57 patients and ON: 30 patients) who underwent medial fixed-bearing UKA with the spacer block technique were retrospectively collected and analyzed. The component gap between the medial tibial osteotomy surface and the femoral trial prosthesis in extension was measured using a UKA tensor, and the preosteotomy gap was calculated in each condition...
March 29, 2024: Journal of Knee Surgery
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