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endoscopic submucosal

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https://www.readbyqxmd.com/read/29236187/mixed-poorly-differentiated-adenocarcinoma-in-undifferentiated-type-early-gastric-cancer-predicts-endoscopic-noncurative-resection
#1
Yusuke Horiuchi, Junko Fujisaki, Noriko Yamamoto, Naoki Ishizuka, Masami Omae, Akiyoshi Ishiyama, Toshiyuki Yoshio, Toshiaki Hirasawa, Yorimasa Yamamoto, Masatsugu Nagahama, Hiroshi Takahashi, Tomohiro Tsuchida
BACKGROUND: Comparisons between surgical cases of mixed poorly differentiated adenocarcinoma and pure signet ring cell carcinoma have revealed higher frequencies of lymph node metastasis and submucosal invasion in the former. However, this comparison has not been reported for endoscopically treated cases. Therefore, we compared cases of curative and noncurative resection in patients who underwent endoscopic submucosal dissection to determine what factors could influence the curative resection rate...
December 13, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29234894/amputation-neuroma-mimicking-lymph-node-metastasis-of-remnant-gastric-cancer-a-case-report
#2
Kenichiro Furukawa, Yutaka Tanizawa, Kimihide Kusafuka, Noriyuki Nishiwaki, Keiichi Fujiya, Hayato Omori, Sanae Kaji, Makoto Hikage, Rie Makuuchi, Tomoyuki Irino, Masanori Tokunaga, Etsuro Bando, Taiichi Kawamura, Masanori Terashima
BACKGROUND: Amputation neuromas (ANs) are reactive hyperplasia of nerve tissues that occur after a trauma or surgery involving the peripheral nerves. Only two previous reports of ANs occurring around the stomach and post gastrectomy have been reported. We report the case of a patient with AN near the remnant stomach who underwent distal gastrectomy for gastric cancer. CASE PRESENTATION: A 76-year-old man underwent distal gastrectomy, D1+ lymphadenectomy, and Billroth-I reconstruction for early gastric cancer in another hospital at 63 years of age...
December 12, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29234120/oral-epithelial-cell-sheets-engraftment-for-esophageal-strictures-after-endoscopic-submucosal-dissection-of-squamous-cell-carcinoma-and-airplane-transportation
#3
Naoyuki Yamaguchi, Hajime Isomoto, Shinichiro Kobayashi, Nobuo Kanai, Kengo Kanetaka, Yusuke Sakai, Yoshiyuki Kasai, Ryo Takagi, Takeshi Ohki, Hiroko Fukuda, Tsutomu Kanda, Kazuhiro Nagai, Izumi Asahina, Kazuhiko Nakao, Masayuki Yamato, Teruo Okano, Susumu Eguchi
Endoscopic submucosal dissection (ESD) permits en bloc removal of superficial oesophageal squamous cell carcinoma (ESCC). However, post-procedure stricture is common after ESD for widespread tumours, and multiple endoscopic balloon dilation (EBD) procedures are required. We aimed to evaluate the safety and effectiveness of endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets that had been transported by air over a distance of 1200 km in controlling postprocedural oesophageal stricture...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233673/conventional-versus-traction-assisted-endoscopic-submucosal-dissection-for-gastric-neoplasms-a-multicenter-randomized-controlled-trial-with-video
#4
Masao Yoshida, Kohei Takizawa, Sho Suzuki, Yoshiki Koike, Satoru Nonaka, Yasushi Yamasaki, Takeyoshi Minagawa, Chiko Sato, Chihiro Takeuchi, Ko Watanabe, Hiromitsu Kanzaki, Hiroyuki Morimoto, Takafumi Yano, Kosuke Sudo, Keita Mori, Takuji Gotoda, Hiroyuki Ono
BACKGROUND AND AIMS: To clarify whether dental floss clip traction improves the technical outcomes of endoscopic submucosal dissection (ESD). METHODS: A superiority, randomized control trial was conducted at 14 institutions across Japan. Patients with single gastric neoplasm meeting the indications of the Japanese guidelines for gastric treatment were enrolled and assigned to receive conventional ESD or dental floss clip traction ESD (DFC-ESD). Randomization was performed according to a computer-generated random sequence with stratification by institution, tumor location, tumor size, and operator experience...
December 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29233113/clinicopathologic-and-endoscopic-features-of-early-stage-colorectal-serrated-adenocarcinoma
#5
Daiki Hirano, Shiro Oka, Shinji Tanaka, Kyoku Sumimoto, Yuki Ninomiya, Yuzuru Tamaru, Kenjiro Shigita, Nana Hayashi, Yuji Urabe, Yasuhiko Kitadai, Fumio Shimamoto, Koji Arihiro, Kazuaki Chayama
BACKGROUND: Serrated adenocarcinoma (SAC) is a distinct colorectal carcinoma variant that accounts for approximately 7.5% of all advanced colorectal carcinomas. While its prognosis is worse than conventional carcinoma, its early-stage clinicopathologic features are unclear. We therefore aimed to clarify the clinicopathologic and endoscopic characteristics of early-stage SACs. METHODS: Forty consecutive early-stage SAC patients at Hiroshima University Hospital were enrolled; SACs were classified into epithelial serration (Group A, n = 17) and non-epithelial serration (Group B, n = 23) groups...
December 12, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29230642/a-case-of-a-protruded-lesion-formed-by-a-poorly-differentiated-intramucosal-adenocarcinoma-of-the-stomach-an-immunohistochemical-analysis
#6
Keiichiro Nakajo, Yasuhiro Oono, Takeshi Kuwata, Tomonori Yano
A 70-year-old woman underwent upper gastrointestinal endoscopy and was found to have a 25-mm protruded lesion in the gastric body. A biopsy revealed malignant cells. Endoscopic submucosal dissection was performed. Histopathologically, the tumor was mainly composed of poorly differentiated adenocarcinoma (PDA), while moderately differentiated adenocarcinoma was observed on its superficial layer. The tumor was located within the mucosal layer. PDAs rarely form a protruded lesion. Here, the presence of a moderately differentiated adenocarcinoma element in the superficial layer of the tumor might have protected the tumor cells from erosion, and solid proliferation of the PDA also contributed to its outward growth...
December 11, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29230559/increased-histopathological-yield-for-granulomatosis-with-polyangiitis-based-on-nasal-endoscopy-of-suspected-active-lesions
#7
Olga Beltrán Rodríguez-Cabo, Edgardo Reyes, Jorge Rojas-Serrano, Luis Felipe Flores-Suárez
PURPOSE: To present the results of an endoscopic and histopathologic evaluation of suspected nasal active granulomatosis with polyangiits (GPA) lesions, describe them as seen by the ENT specialist, and propose a guide for tissue sampling of the nasal cavity to improve the yield of confirmatory histology. METHODS: Randomly selected patients seen from December 1997-October 2007 had a thorough endoscopic nasal evaluation, preceded by careful cleansing of the nasal cavity...
December 11, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29228981/composite-neuroendocrine-tumor-and-adenocarcinoma-of-the-rectum
#8
Hiromi Kanno-Okada, Tomoko Mitsuhashi, Katsuhiro Mabe, Tadakazu Shimoda, Yoshihiro Matsuno
BACKGROUND: Although adenocarcinomas showing neuroendocrine differentiation or those mixed with high-grade neuroendocrine carcinoma (NEC) are sometimes encountered, composite tumors comprising neuroendocrine tumor (NET) Grade 1 and adenocarcinoma are exceedingly rare. CASE PRESENTATION: A 64-year-old male presented after testing positive for fecal occult blood at a medical check-up. A biopsy demonstrated the presence of a NET and endoscopic submucosal dissection was undertaken...
December 11, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/29228128/evaluation-of-a-novel-infra-red-endoscopy-system-in-the-assessment-of-early-neoplasia-in-barretts-esophagus-pilot-study-from-a-single-center
#9
J Ortiz-Fernandez-Sordo, S Sami, R Mansilla-Vivar, V Subramanian, J Mannath, E Telakis, K Ragunath
Infrared endoscopy (IRE) has been shown to be useful in detecting submucosal (SM) invasion in early gastric cancer. Its role in the endoscopic assessment of Barrett's neoplasia has not been reported to date. We aimed in this study to evaluate the role of IRE in the detection and characterization of early neoplastic lesions within Barrett's esophagus (BE). The secondary aim was to explore its usefulness for the assessment of the presence of submucosal invasion in these early neoplastic Barrett's lesions. We included in the study patients with dysplastic BE who were referred to our institution for endoscopic therapy of a previously diagnosed early Barrett's neoplasia...
December 8, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29226661/completely-responsive-multiple-liver-recurrence-of-colon-cancer-treated-using-chemotherapy-with-oral-s-1-and-oxaliplatin-plus-bevacizumab-a-case-report
#10
Akira Kabashima, Koichi Kimura, Kensakuet Sanefuji, Soichiro Maekawa
Although chemotherapy with oral S-1and oxaliplatin (SOX) plus bevacizumab (bev) is safe and feasible for patients with advanced or recurrent colorectal cancer, it is difficult to achieve a complete response (CR) using only chemotherapy. A 67-year-old man underwent endoscopic mucosal resection and additional sigmoidectomy (D2 dissection) for submucosal invasive sigmoid colon cancer. Multiple liver metastases were diagnosed 1.5 years later, and chemotherapy with SOX + bev was initiated. Computed tomography (CT) after the end of the third course revealed reduced liver recurrence...
January 2017: Fukuoka Igaku Zasshi, Hukuoka Acta Medica
https://www.readbyqxmd.com/read/29226475/a-double-scope-method-for-creating-a-straight-submucosal-tunnel-during-peroral-endoscopic-myotomy
#11
Hironari Shiwaku, Kanefumi Yamashita, Suguru Hasegawa
Peroral endoscopic myotomy (POEM) is a revolutionary treatment for achalasia.1-3 It involves creating a submucosal tunnel directly to the stomach side; theoretically, a straight tunnel can be obtained by creating it perpendicular to the inner annulus muscle. Clinically, this is not always easy; therefore, we introduced a new method for controlling the submucosal tunnel direction in which a small-diameter endoscope is inserted along with the main endoscope. This allows us to check the illumination of the main scope in the submucosal layer, which can be particularly useful when treating a sigmoid-type anomaly with a highly flexed esophagus...
December 11, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29226218/clinical-effectiveness-of-the-pocket-creation-method-for-colorectal-endoscopic-submucosal-dissection
#12
Akira Kanamori, Masakazu Nakano, Masayuki Kondo, Takanao Tanaka, Keiichiro Abe, Tsunehiro Suzuki, Hitoshi Kino, Yoshihito Kaneko, Chieko Tsuchida, Kouhei Tsuchida, Naoto Yoshitake, Keiichi Tominaga, Yasuo Imai, Hideyuki Hiraishi
Background and study aims : Endoscopic submucosal dissection (ESD) is a technically advanced procedure for colorectal tumors. Hayashi et al. invented the "pocket-creation method (PCM)," and reported that Is-type lesions with fibrosis could be efficaciously and safely resected. However, only case studies have been published, and there are no previous reports on the usefulness of PCM in colorectal ESD for all lesions, as compared with the conventional method. This study aimed to evaluate the effectiveness and safety of PCM in colorectal ESD...
December 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29225836/cardiac-tamponade-occurred-after-endoscopic-submucosal-dissection-conservative-management-of-the-esophagopericardial-fistula
#13
Davide Bona, Greta Isabella Saino, Massimo Medda, Valerio Panizzo, Giancarlo Micheletto
We describe the case of an esophagopericardial fistula generated after endoscopic submucosal dissection in a patient affected by a superficial esophageal squamous cell carcinoma immediately treated with percutaneous pericardial drainage and placement of a partially covered self-expanding metal stent that has been removed using the stent-in-stent technique after 35 days.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29225256/gastric-adenocarcinoma-of-the-fundic-gland-type-after-endoscopic-therapy-for-metachronous-gastric-cancer-a-case-report
#14
Hitoshi Kino, Masakazu Nakano, Akira Kanamori, Tsunehiro Suzuki, Yoshihito Kaneko, Chieko Tsuchida, Kouhei Tsuchida, Keiichi Tominaga, Takako Sasai, Hidetsugu Yamagishi, Yasuo Imai, Hideyuki Hiraishi
A 78-year-old man underwent endoscopic submucosal dissection (ESD) for early gastric adenocarcinoma twice in 2009 and 2014. Between the procedures, he successfully completed Helicobacter pylori eradication therapy. In May 2015, upper endoscopy screening showed two elevated lesions on the gastric fundus, and en bloc resection by ESD was performed. We histopathologically diagnosed the patient to have gastric adenocarcinoma of the fundic gland type. In this case, the two lesions of gastric adenocarcinoma of the fundic gland type multifocally developed after ESD for metachronous gastric tubular adenocarcinoma...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29223381/a-case-of-ceco-colonic-intussusception-after-the-endoscopic-submucosal-dissection-of-a-cecal-adenoma
#15
Osamu Araki, Akihisa Fukuda, Toshihiro Kusaka, Hiroshi Seno
No abstract text is available yet for this article.
December 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29222735/delayed-perforation-after-endoscopic-submucosal-dissection-treated-successfully-by-temporary-stent-placement
#16
Masami Omae, Magnus Konradsson, Francisco Baldaque-Silva
A 71-year-old male patient with a long-segment (C10M12) Barrett's esophagus harboring multifocal high-grade dysplasia was referred to our clinic. After a multidisciplinary team conference and the patient's informed consent, an endoscopic submucosal dissection (ESD) was performed with resection of 4/5 of the esophageal circumference along 12 cm, without any complications during or immediately after the procedure. In the day after the ESD, the patient presented suddenly with dyspnea and subcutaneous emphysema in the neck and chest...
December 8, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29220859/single-and-double-tunnel-endoscopic-submucosal-tunnel-dissection-for-large-superficial-esophageal-squamous-cell-neoplasms
#17
Wengang Zhang, Yaqi Zhai, Ningli Chai, Enqiang Linghu, Huikai Li, Xiuxue Feng
Background and study aim Single-tunnel endoscopic submucosal tunnel dissection (ESTD) has shown promising preliminary efficacy for large superficial esophageal squamous cell neoplasms (SESCNs). This study reports the outcomes of both single- and double-tunnel ESTD for large SESCNs, and compares the efficiency of the two techniques for treating circumferential SESCNs. Patients and methods 46 patients with large SESCNs underwent ESTD at a single hospital between October 2011 and March 2016. Relevant clinical data were retrospectively collected and analyzed...
December 8, 2017: Endoscopy
https://www.readbyqxmd.com/read/29218732/single-center-implementation-of-endoscopic-submucosal-dissection-esd-in-colorectum-low-recurrence-rate-after-intention-to-treat-esd
#18
Andrej Wagner, Daniel Neureiter, Tobias Kiesslich, Gernot W Wolkersdörfer, Thomas Pleininger, Christian Mayr, Christiane Dienhart, Naohisa Yahagi, Tsuneo Oyama, Frieder Berr
OBJECTIVES: Colorectal endoscopic submucosal dissection (ESD) shows higher R0 resection and lower local recurrence rates than endoscopic mucosal resection (EMR) in Japan. In Europe, independent learning of ESD in colorectum is feasible, but yet to be analyzed for curative resection and recurrence rates. METHODS: After experimental training under supervision by Japanese experts (T.O., N.Y.), three endoscopists independently performed 83 ESD procedures intention-to-treat for lesions in the entire colorectum of 67 patients in a prospective registry (Nov...
December 8, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29218674/correction-to-long-term-outcomes-of-patients-with-early-gastric-cancer-found-to-have-lesions-for-which-endoscopic-treatment-is-not-indicated-on-histopathological-evaluation-after-endoscopic-submucosal-dissection
#19
Takafumi Yano, Kenji Ishido, Satoshi Tanabe, Takuya Wada, Mizutomo Azuma, Natsuko Kawanishi, Sakiko Yamane, Akinori Watanabe, Chikatoshi Katada, Wasaburo Koizumi
In Table 1, the second item in the right-hand column "Extra-indication" should be changed to "Out of indication". The correct version of Table 1 is displayed.
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29218566/gastric-neuroendocrine-tumor-arising-from-heterotopic-pancreas
#20
Takehiro Tanaka, Rika Omote, Noriko Okazaki, Hiroyuki Yanai, Tadashi Yoshino
There are few English reports on secondary tumors from heterotopic pancreas. Here, we describe a case of gastric neuroendocrine tumor (NET) arising from heterotopic pancreas. A 72-year-old woman underwent esophagogastroduodenoscopy as part of a general health check-up. An endoscopic examination revealed a submucosal tumor on the greater curvature of the gastric body. Laparoscopic and endoscopic cooperative surgery was performed. Histological diagnosis concluded that it was a Grade 1 NET arising from heterotopic pancreas...
December 7, 2017: Clinical Journal of Gastroenterology
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