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endoscopic submucosal

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https://www.readbyqxmd.com/read/28449342/gastrointestinal-gastric-perforation-during-esophageal-endoscopic-submucosal-dissection-a-serious-adverse-event-in-a-patient-with-esophageal-stricture
#1
K Hamada, Y Takeuchi, N Matsuura, K Higashino, R Ishihara
No abstract text is available yet for this article.
May 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28449151/french-comment-on-article-laparoscopic-and-luminal-endoscopic-cooperative-surgery-can-be-a-standard-treatment-for-submucosal-tumors-of-the-stomach-a-retrospective-multicenter-study
#2
https://www.readbyqxmd.com/read/28449143/selection-bias-complicates-comparisons-of-endoscopic-submucosal-dissection-vs-endoscopic-mucosal-resection-in-the-treatment-of-colorectal-neoplasms
#3
Takashi Kanesaka, Ervin Toth, Henrik Thorlacius
No abstract text is available yet for this article.
May 2017: Endoscopy
https://www.readbyqxmd.com/read/28447005/future-directions-in-esophageal-cancer-therapy
#4
Ori Wald, Brandon Smaglo, Henry Mok, Shawn S Groth
Resection techniques for esophageal carcinoma continue to evolve, from endoscopic mucosal resection or endoscopic submucosal dissection for early stage disease to standard and robot-assisted minimally invasive esophagectomy as part of multimodal therapy for locally advanced disease. Though currently limited to assessing conduit perfusion and sentinel lymph nodes, embedded technology in the robotic surgical platform will likely play an expanded role during esophagectomy in the future. The use of targeted therapies, checkpoint inhibitors, engineered immune cell therapy, and cancer vaccines show promise in the treatment of systemic disease...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28446997/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-early-stage-esophageal-cancer
#5
REVIEW
Bo Ning, Mohamed M Abdelfatah, Mohamed O Othman
Mortality from esophageal cancer remains high despite advances in medical therapy. Although the incidence of squamous cell carcinoma of the esophagus remains unchanged, the incidence of the esophageal adenocarcinoma has increased over time. Gastroesophageal reflux disease (GERD and obesity are contributing factors to the development of Barrett's esophagus and subsequent development of adenocarcinoma. Early recognition of the disease can lead to resection of esophageal cancer prior to the development of lymphovascular invasion...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28445280/clinical-outcome-after-endoscopic-submucosal-dissection-for-early-gastric-cancer-of-absolute-and-expanded-indication
#6
Ju Seok Kim, Sun Hyung Kang, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee, Hyun Yong Jeong
This study evaluated the clinical outcome of endoscopic submucosal dissection (ESD) in minute submucosa (SM) invasion or undifferentiated early gastric cancer (EGC) and analyzed factors related to local recurrence after ESD.We retrospectively reviewed the chart of EGC patients, who underwent ESD at our tertiary hospital between January 2009 and 2015. The patients' characteristics and clinical outcomes were compared among an absolute indication, minute SM invasion, and undifferentiated EGC group.Of 885 total patients, 729 composed the absolute indication group; 65, the differentiated, SM invasion group; and 51, the undifferentiated, confined mucosa group...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28440945/heterogeneity-in-esophageal-and-gastric-cardia-precursor-progression-during-six-year-endoscopic-surveillance-after-population-based-screening-in-a-chinese-high-risk-region
#7
Denggui Wen, Liwei Zhang, Xiaoling Wang, Xiaoduo Wen, Yi Yang, Yuetong Chen, Guiying Wang, Kohei Akazawa, Shijie Wang, Baoen Shan
BACKGROUND: The study was conducted to examine esophageal and gastric cardia precursor progression. METHODS: After population-based baseline screening, 145 precursor and 335 chronic inflammation cases were endoscopically surveyed for six years. RESULTS: Surveillance of interval and baseline diagnoses for 18 severe dysplasia (SD) cases later detected were: 13, 23, 39, and 44 months since a diagnosis of chronic inflammation in four cases; 6, 6, 6, 11, 13, 16, 16, and 23 months since mild dysplasia (mD) diagnoses in eight; and 6, 9, 10, 13, 18, and 48 months since moderate dysplasia (MD) diagnoses in six...
April 25, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28434216/can-endoscopic-ulcerations-in-early-gastric-cancer-be-clearly-defined-before-endoscopic-resection-a-survey-among-endoscopists
#8
Sung Min Park, Byung-Wook Kim, Joon Sung Kim, Young Wook Kim, Gi Jun Kim, Seung Ji Ryu
Background/Aims: Early gastric cancer (EGC) with ulcerations can be treated via endoscopic resection (ER) when it is differentiated pathologically, limited to the mucosa, and <3 cm in diameter. The presence of ulceration is a key factor in deciding treatment strategies and is usually diagnosed during endoscopic examination. The aim of this study was to evaluate whether ulcerations in EGC can be clearly defined among endoscopists and which factors are related to the differences. Methods: A survey questionnaire, composed of demographic features and endoscopic images of seven patients with EGC, was presented to the endoscopists via e-mail...
April 24, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28425665/standardization-of-endoscopic-resection-for-colorectal-tumors-larger-than-10%C3%A2-mm-in-diameter
#9
Shiro Oka, Toshio Uraoka, Naoto Tamai, Hiroaki Ikematsu, Akiko Chino, Koichi Okamoto, Yoji Takeuchi, Kenichiro Imai, Ken Ohata, Hisashi Shiga, Spiro Raftopoulos, Bo-In Lee, Takahisa Matsuda
Currently, several endoscopic resection (ER) methods for colorectal tumors are available, including polypectomy, conventional endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and modified ER. In the present review, we mainly focus on the current status of ER for colorectal tumors as well as the report from the Endoscopic Forum Japan (EFJ) 2016, which was held in Tokyo in August 2016. The proposed ER methods for colorectal tumors larger than 10 mm in diameter are as follows. (i) Pedunculated-type tumor is an indication for polypectomy, regardless of size...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28425662/feasibility-of-colorectal-endoscopic-submucosal-dissection-esd-carried-out-by-endoscopists-with-no-or-little-experience-in-gastric-esd
#10
Hisashi Shiga, Reina Ohba, Tamotsu Matsuhashi, Mario Jin, Masatake Kuroha, Katsuya Endo, Rintaro Moroi, Shoichi Kayaba, Katsunori Iijima
BACKGROUND AND AIM: Colorectal endoscopic submucosal dissection (ESD) is recommended to be carried out only by endoscopists with sufficient experience in gastric ESD. However, early gastric carcinoma is less common in Western countries than in Japan, and endoscopic maneuverability differs between the stomach and colorectum. We assessed the feasibility of colorectal ESD carried out by endoscopists with no or little experience in gastric ESD. METHODS: We analyzed en bloc resection, R0 resection and perforation rates in 180 consecutive colorectal ESD carried out by three endoscopists who had no or <5 cases of experience in gastric ESD...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28425660/endoscopic-submucosal-dissection-for-large-colorectal-neoplasms
#11
Kenichiro Imai, Kinichi Hotta, Yuichiro Yamaguchi, Sayo Ito, Hiroyuki Ono
BACKGROUND AND AIM: Endoscopic submucosal dissection (ESD) for colorectal neoplasms (CRN) of >50 mm is considered technically difficult. The ITknife nano™ was developed specifically for ESD of CRN and esophageal superficial neoplasms; however, only limited data are available regarding its use in this procedure. Here we assessed the safety and efficacy of ESD using the ITknife nano™ for large CRN (>50 mm). METHODS: We carried out a retrospective study, including consecutive patients with CRN larger than 50 mm that were treated by ESD between September 2002 and August 2016 at our institution...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28425649/efficacy-of-hybrid-endoscopic-submucosal-dissection-esd-as-a-rescue-treatment-in-difficult-colorectal-esd-cases
#12
Koichi Okamoto, Naoki Muguruma, Kaizo Kagemoto, Yasuhiro Mitsui, Daisaku Fujimoto, Shinji Kitamura, Tetsuo Kimura, Masahiro Sogabe, Hiroshi Miyamoto, Tetsuji Takayama
BACKGROUND AND AIM: Endoscopic submucosal dissection (ESD), which provides a higher en bloc resection rate than conventional endoscopic mucosal resection (EMR), is considered to be a useful treatment option for large colorectal tumors. However, colorectal ESD is not widely used because of its technical difficulty, risk of complications and time required. To overcome these drawbacks, a simpler modified technique, ESD with snaring (hybrid ESD), has been developed. The aim of the present study was to retrospectively compare the safety and efficacy of hybrid ESD and conventional ESD for colorectal tumors...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28424913/can-further-gastrectomy-be-avoided-in-patients-with-incomplete-endoscopic-resection
#13
Hee Sung Kim, Ji Yong Ahn, Seon Ok Kim, Byung Sik Kim
BACKGROUND: Endoscopic resection (ER) is a widely accepted treatment for patients with early gastric cancer (EGC) with no lymph node metastasis. Occasionally, however, additional surgery is needed due to an incomplete resection. The purpose of this study was to detect clinical factors which might identify patients at greater risk of additional surgery after ER and to suggest an alternative treatment strategy for these patients. METHODS: This study retrospectively analyzed 350 patients with gastric cancer who underwent radical gastrectomy and lymphadenectomy after ER in a single institution between July 2004 and July 2014...
April 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28424911/long-term-outcomes-of-endoscopic-resection-of-gastric-gists
#14
Changji Yu, Guobin Liao, Chaoqiang Fan, Jing Yu, Xubiao Nie, Shiming Yang, Jianying Bai
OBJECTIVE: Although the endoscopic treatment of gastric stromal tumors is a recently accepted therapy, the long-term outcomes of this approach remain unknown. The aims of this study were to assess the long-term effectiveness and safety of endoscopic resection for gastric GISTs. METHODS: A total of 60 consecutive patients undergoing endoscopic resection of gastric GISTs were enrolled in a retrospective single-center study. Clinical data, perioperative complications, histopathologic characteristics of the tumors, and long-term outcomes were recorded...
April 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28420894/outcome-of-radiation-monotherapy-for-high-risk-patients-with-stage-i-esophageal-cancer
#15
Yasuhiro Shirakawa, Kazuhiro Noma, Naoaki Maeda, Shunsuke Tanabe, Shinji Kuroda, Shunsuke Kagawa, Kuniaki Katsui, Norihisa Katayama, Susumu Kanazawa, Toshiyoshi Fujiwara
Currently, chemoradiation is the most widely used nonsurgical treatment for esophageal cancer. However, some patients, particularly the very elderly or those with severe vital organ dysfunction, face difficulty with the chemotherapy component. We therefore examined the outcome of radiation therapy (RT) alone for patients with esophageal cancer at our facility. Between January 2005 and December 2014, 84 patients underwent RT at our hospital, and 78 of these patients received concomitant chemotherapy. The remaining 6 patients underwent RT alone; these patients were considered to be high-risk and to have no lymph node metastasis (stage I)...
April 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28412758/endoscopic-diagnosis-of-primary-anorectal-melanoma
#16
Wang Sheng, Sun Siyu, Liu Xiang, Ge Nan, Wang Guoxin, Guo Jintao, Liu Wen, Wang Shupeng
OBJECTIVE: The present study retrospectively analyzed case data from 12 patients diagnosed with anorectal melanoma, with the purpose of identifying key diagnostic features at endoscopy. MATERIALS AND METHODS: Images from colonoscopy were reviewed for all patients in order to establish the endoscopic features of primary anorectal melanoma. For the patients whose colonoscopic examinations included endoscopic ultrasound, images were examined to characterize lesions and the depth of infiltration, the results of which were compared with pathological findings after operative resection...
February 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28409376/clinicopathologic-features-of-early-gastric-carcinoma-with-lymphoid-stroma-and-feasibility-of-endoscopic-submucosal-dissection
#17
Dong Hun Shin, Gwang Ha Kim, Bong Eun Lee, Jong Wook Lee, Dong Woo Ha, Hye Kyung Jeon, Dong Hoon Baek, Geun Am Song, Sang Jeong Ahn, Do Youn Park
BACKGROUND: Gastric carcinoma with lymphoid stroma (GCLS) is a rare disease known to have unique features and a favorable prognosis. This study aimed to determine the clinicopathologic features of early GCLS (EGCLS) and define the feasibility of endoscopic submucosal dissection (ESD) for EGCLS. METHODS: We performed a retrospective analysis of 70 EGCLS patients treated via ESD or surgery and 1626 patients who underwent surgical resection for early non-GCLS (ENGCLS) between January 2007 and December 2014 at Pusan National University Hospital, Busan, Republic of Korea...
April 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28409375/fluoroscopy-guided-gastric-peroral-endoscopic-pyloromyotomy-g-poem-a-more-reliable-and-efficient-method-for-treatment-of-refractory-gastroparesis
#18
H B Xue, H Z Fan, X M Meng, S Cristofaro, P Mekaroonkamol, S Dacha, L Y Li, X L Fu, S H Zhan, Q Cai
INTRODUCTION: Prior studies show promising results of the gastric peroral endoscopic pyloromyotomy (G-POEM) procedure for treatment of refractory gastroparesis. One major technical challenge involved in this procedure is identifying the pyloric muscular ring (PMR). The aim of this study is to establish a reliable method for identification of the PMR during G-POEM. METHODS: Fluoroscopy-guided G-POEM was performed by placing an endoclip at the 9 to 11'o clock position at the pylorus for identification of PMR...
April 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28408991/transplantation-of-tissue-engineered-cell-sheets-for-stricture-prevention-after-endoscopic-submucosal-dissection-of-the-oesophagus
#19
Eduard Jonas, Sebastian Sjöqvist, Peter Elbe, Nobuo Kanai, Jenny Enger, Stephan L Haas, Ammar Mohkles-Barakat, Teruo Okano, Ryo Takagi, Takeshi Ohki, Masakazu Yamamoto, Makoto Kondo, Katrin Markland, Mei Ling Lim, Masayuki Yamato, Magnus Nilsson, Johan Permert, Pontus Blomberg, J-Matthias Löhr
BACKGROUND AND OBJECTIVE: Endoscopic mucosal dissection (ESD) is a treatment option for oesophagus tumours localized to the mucosa enabling en bloc removal of large lesions. The resulting larger mucosal defects have resulted in an increase in the occurrence of post-treatment strictures. Transplantation of autologous cell sheets, cultured from oral mucosa, has been shown to prevent post-ESD strictures. The aim of the study was to assess the efficacy and safety of cell sheet transplantation after oesophageal ESD in a Western patient population where reflux-associated pre-malignant and malignant conditions predominate...
December 2016: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28405321/the-expansion-of-endoscopic-submucosal-dissection-in-france-a-prospective-nationwide-survey
#20
Maximilien Barret, Vincent Lepilliez, Dimitri Coumaros, Stanislas Chaussade, Sarah Leblanc, Thierry Ponchon, Fabien Fumex, Edouard Chabrun, Paul Bauret, Christophe Cellier, Emmanuel Coron, Philippe Bichard, Philippe Bulois, Antoine Charachon, Gabriel Rahmi, Serge Bellon, Marc Lerhun, Jean-Pierre Arpurt, Stéphane Koch, Bertrand Napoleon, Eric Vaillant, Anouk Esch, Said Farhat, Francoise Robin, Nadira Kaddour, Frédéric Prat
INTRODUCTION: Early reports of endoscopic submucosal dissection (ESD) in Europe suggested high complication rates and disappointing outcomes compared to publications from Japan. Since 2008, we have been conducting a nationwide survey to monitor the outcomes and complications of ESD over time. MATERIAL AND METHODS: All consecutive ESD cases from 14 centers in France were prospectively included in the database. Demographic, procedural, outcome and follow-up data were recorded...
February 2017: United European Gastroenterology Journal
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