Huan Tang, Xin Miao, Cheng Yu, Changpeng Chai, Yuanhui Su, Lu Li, Jianfeng Yi, Zhenzhen Ye, Long Miao, Zhengfeng Wang, Hui Zhang, Hao Xu, Wence Zhou
Chemotherapy resistance poses clinical challenges in pancreatic cancer treatment. Developing cell lines resistant to chemotherapy is crucial for investigating drug resistance mechanisms and identifying alternative treatment pathways. The genetic and biological attributes of pancreatic cancer depend on its aetiology, racial demographics and anatomical origin, underscoring the need for models that comprehensively represent these characteristics. Here, we introduce PDAC-X2, a pancreatic cancer cell line derived from Chinese patients...
April 22, 2024: Scientific Reports