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https://www.readbyqxmd.com/read/28628446/diphtheria-in-mayotte-2007-2015
#1
Emmanuel Belchior, Sabine Henry, Edgar Badell, Louis Collet, Thierry Benoit-Cattin, Anne-Marie de Montera, Nicole Guiso, Olivier Patey, Daniel Levy-Bruhl, Laurent Filleul, Francois Chieze, Sophie Olivier
Epidemiology of diphtheria in the southwestern Indian Ocean is poorly documented. We analyzed 14 cases of infection with toxigenic Corynebacterium diphtheriae reported during 2007-2015 in Mayotte, a French department located in this region. Local control of diphtheria is needed to minimize the risk for importation of the bacterium into disease-free areas.
July 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28614437/chronic-disease-in-childhood-and-adolescence-continuity-of-care-in-the-health-care-network
#2
Vanessa Medeiros da Nóbrega, Maria Elizabete de Amorim Silva, Leiliane Teixeira Bento Fernandes, Claudia Silveira Viera, Altamira Pereira da Silva Reichert, Neusa Collet
OBJECTIVE: To evaluate the continuity of care for children and adolescents with chronic diseases in the health care network. METHODS: This qualitative study was conducted between February and October 2013 with 12 families, six health managers, and 14 health professionals from different health care services in a municipality of the state of Paraíba, Brazil, using focal groups, semi-structured interviews, and medical record consultation. The data were analyzed by triangulation and thematic analysis...
June 12, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28598528/use-of-radar-detectors-to-track-attendance-of-albatrosses-at-fishing-vessels
#3
H Weimerskirch, D P Filippi, J Collet, S M Waugh, S C Patrick
Despite international waters covering over 60% of the world's oceans, our understanding of how fisheries in these regions shape ecosystem processes is surprisingly poor. Seabirds are known to forage at fishing vessels, with potential deleterious effects for their population, but the extent of overlap and behavior in relation to ships are poorly known. Using novel biologging devices, which can detect radar emissions to record the position of boats and seabirds, we measured the true extent of the overlap between seabirds and fishing vessels, and generated estimates of the intensity of fishing and distribution of vessels in international waters...
June 9, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28596159/in-vivo-relationship-between-hypoxia-and-angiogenesis-in-human-glioblastoma-a-multimodal-imaging-study
#4
Keven Ferreira da Ponte, David Hassanein Berro, Solène Collet, Jean-Marc Constans, Evelyne Emery, Samuel Valable, Jean-Sébastien Guillamo
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor. This aggressiveness is in part attributed to the closely interrelated phenomena, tumor hypoxia and angiogenesis, although few in vivo data exist in human brain tumors. This work aims to study hypoxia and angiogenesis, in vivo and in situ, in patients admitted with GBM using multimodal imaging. Methods: 23 GBM patients were assessed by [(18)F]-FMISO PET and conventional and perfusion MRI prior to surgery. The level and location of hypoxia ([(18)F]-FMISO uptake, evaluated by tumor/blood ratio, T/B), vascularization (cerebral blood volume, CBV) and vascular permeability (contrast enhancement after gadolinium injection) were analyzed...
June 8, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28592235/gene-centromere-mapping-in-meiotic-gynogenetic-european-seabass
#5
Münevver Oral, Julie Colléter, Michaël Bekaert, John B Taggart, Christos Palaiokostas, Brendan J McAndrew, Marc Vandeputte, Béatrice Chatain, Heiner Kuhl, Richard Reinhardt, Stefano Peruzzi, David J Penman
BACKGROUND: Fully isogenic lines in fish can be developed using "mitotic" gynogenesis (suppression of first zygotic mitosis following inactivation of the sperm genome). However, genome-wide verification of the steps in this process has seldom been applied. We used ddRADseq to generate SNP markers in a meiotic gynogenetic family of European seabass (Dicentrarchus labrax): (i) to verify the lack of paternal contribution in a meiotic gynogenetic family; (ii) to generate a gene-centromere map from this family; (iii) to identify telomeric markers that could distinguish mitotic gynogenetics from meiotic gynogenetics, which sometimes arise spontaneously in mitotic gynogenetic families...
June 7, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28590249/difference-in-hemodynamic-microenvironment-in-vessels-scaffolded-with-absorb-bvs-and-mirage-brms-insights-from-a-pre-clinical-endothelial-shear-stress-study
#6
Erhan Tenekecioglu, Ryo Torii, Christos Bourantas, Yohei Sotomi, Rafael Cavalcante, Yaping Zeng, Carlos Collet, Tom Crake, Pannipa Suwannasom, Yoshinobu Onuma, Patrick W Serruys
AIMS: In silico studies have provided robust evidence that stent design affects local hemodynamic forces, which appear as a major determinant of clinical outcomes following stent implantation. However, implications of different stent/scaffold configurations on local hemodynamic forces have not yet been investigated in vivo in a comparative fashion. METHOD AND RESULTS: Eight healthy mini pigs were implanted with six Absorb everolimus-eluting Bioresorbable Vascular Scaffolds (Absorb BVS) and five Mirage sirolimus-eluting Bioresorbable Microfiber Scaffolds (Mirage BRMS)...
June 6, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28573375/chronic-maxillary-atelectasis-and-silent-sinus-syndrome-two-faces-of-the-same-clinical-entity
#7
Clotilde de Dorlodot, Stephanie Collet, Philippe Rombaux, Mihaela Horoi, Sergio Hassid, Philippe Eloy
Chronic maxillary atelectasis (CMA) and silent sinus syndrome (SSS) are rare clinical entities characterized by an implosion of the maxillary sinus that may or may not be associated with sinonasal symptoms, and are complicated by ipsilateral enophthalmos. The objective of this article is to discuss the definitions, physiopathology, clinical and radiographic characteristics, and surgical management of these entities. We retrospectively reviewed 18 patients (7 women, 11 men, aged 12-70 years) diagnosed and treated in the ear, nose, and throat departments of four Belgian teaching hospitals between 2000 and 2015...
June 1, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28567706/the-effect-of-strut-thickness-on-shear-stress-distribution-in-a-preclinical-model
#8
Erhan Tenekecioglu, Ryo Torii, Christos Bourantas, Yosuke Miyazaki, Carlos Collet, Rasha Al-Lameé, Kadem Al-Lameé, Yoshinobu Onuma, Patrick W Serruys
No abstract text is available yet for this article.
May 31, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28553415/use-of-proviral-dna-to-investigate-virus-resistance-mutations-in-hiv-infected-zimbabweans
#9
Tutsirai V Musingwini, Danai T Zhou, Doreen Mhandire, Kerina Duri, Exnevia Gomo, Olav Oktedalen, Benjamin Chimukangara, Tinei Shamu, Sandra Shawarira-Bote, Collet Dandara, Babill Stray-Pedersen
BACKGROUND: Antiretroviral therapy (ART) to suppress HIV replication has reduced morbidity and mortality yet effectiveness of current HIV drugs is threatened by HIV drug resistance (HIVDR) mutations. OBJECTIVE: To determine HIVDR mutations using proviral DNA from specimens of patients presenting to an HIV treatment clinic. METHODS: DNA from 103 patients, 86 treatment-experienced, 17 treatment-naïve, were genotyped for the HIV-1C reverse transcriptase gene (RT; codons 21-304) using Sanger sequencing and sequences analyzed using Sequencher software...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28552862/imbalanced-angiogenesis-in-peripartum-cardiomyopathy%C3%A3-diagnostic-value-of-placenta-growth-factor
#10
Alexandre Mebazaa, Marie-France Seronde, Etienne Gayat, Kemi Tibazarwa, Dilly O C Anumba, Najla Akrout, Malha Sadoune, Jamela Sarb, Mattia Arrigo, Justina Motiejunaite, Said Laribi, Matthieu Legrand, Lydia Deschamps, Loubina Fazal, Lila Bouadma, Corinne Collet, Philippe Manivet, Alain Cohen Solal, Jean-Marie Launay, Jane-Lise Samuel, Karen Sliwa
BACKGROUND: Concentrations of the anti-angiogenic factor soluble fms-like tyrosine kinase-1 (sFlt-1) are altered in peripartum cardiomyopathy (PPCM). In this study we investigated changes in the angiogenesis balance in PPCM.Methods and Results:Plasma concentrations of sFlt-1 and the pro-angiogenic placenta growth factor (PlGF) were determined in patients with PPCM during the post-partum phase (n=83), in healthy women at delivery (n=30), and in patients with acute heart failure (AHF; n=65)...
May 27, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28540210/integration-of-non-invasive-functional-assessments-with-anatomical-risk-stratification-in-complex-coronary-artery-disease-the-non-invasive-functional-syntax-score
#11
REVIEW
Carlos Collet, Yoshinobu Onuma, Yosuke Miyazaki, Marie-Angèle Morel, Patrick W Serruys
Since the early days of coronary angiography, the extension and severity of coronary artery disease (CAD) have been used for risk stratification. The SYNTAX score objectively characterizes CAD in patients with multivessel disease. Furthermore, recalculating the SYNTAX score by the incorporation of the functional component coronary stenosis (i.e., FFR) increases the discrimination for the risk of adverse events. The calculation of the SYNTAX score derived from non-invasive modalities such as coronary computed tomography angiography (CTA) has emerged as a mean to obtain the SYNTAX score before invasive cardiac catheterization...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28537270/coherent-structural-trapping-through-wave-packet-dispersion-during-photoinduced-spin-state-switching
#12
Henrik T Lemke, Kasper S Kjær, Robert Hartsock, Tim B van Driel, Matthieu Chollet, James M Glownia, Sanghoon Song, Diling Zhu, Elisabetta Pace, Samir F Matar, Martin M Nielsen, Maurizio Benfatto, Kelly J Gaffney, Eric Collet, Marco Cammarata
The description of ultrafast nonadiabatic chemical dynamics during molecular photo-transformations remains challenging because electronic and nuclear configurations impact each other and cannot be treated independently. Here we gain experimental insights, beyond the Born-Oppenheimer approximation, into the light-induced spin-state trapping dynamics of the prototypical [Fe(bpy)3](2+) compound by time-resolved X-ray absorption spectroscopy at sub-30-femtosecond resolution and high signal-to-noise ratio. The electronic decay from the initial optically excited electronic state towards the high spin state is distinguished from the structural trapping dynamics, which launches a coherent oscillating wave packet (265 fs period), clearly identified as molecular breathing...
May 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28520952/defining-optimal-health-range-for-thyroid-function-based-on-the-risk-of-cardiovascular-disease
#13
L Chaker, T I M Korevaar, D Rizopoulos, T-H Collet, H Völzke, A Hofman, N Rodondi, A R Cappola, R P Peeters, O H Franco
Context: Reference ranges of thyroid stimulating hormone (TSH) and free thyroxine (FT4) are defined by their distribution in apparently healthy populations, (2.5th and 97.5th percentiles) irrespective of disease risk and used as cut-offs for defining and clinically managing thyroid dysfunction. Objective: To provide a proof of concept in defining thyroid function optimal health ranges based on cardiovascular disease (CVD) mortality risk. Design and Participants: 9,233 participants from the Rotterdam Study (mean age 65...
May 17, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28515870/behavioral-responses-to-encounter-of-fishing-boats-in-wandering-albatrosses
#14
Julien Collet, Samantha C Patrick, Henri Weimerskirch
Animals are attracted to human food subsidies worldwide. The behavioral response of individuals to these resources is rarely described in detail, beyond chances of encounters. Seabirds for instance scavenge in large numbers at fishing boats, triggering crucial conservation issues, but how the response to boats varies across encounters is poorly known. Here we examine the behavioral response of wandering albatrosses (Diomedea exulans), equipped with GPS tags, to longline fishing boats operating near their colony for which we had access to vessel monitoring system data...
May 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28510325/structural-dynamics-upon-photoexcitation-in-a-spin-crossover-crystal-probed-with-femtosecond-electron-diffraction
#15
Yifeng Jiang, Lai Chung Liu, Henrike M Müller-Werkmeister, Cheng Lu, Dongfang Zhang, Ryan L Field, Antoine Sarracini, Gustavo Moriena, Eric Collet, R J Dwayne Miller
Photoexcitation of spin crossover (SCO) complexes can trigger extensive electronic spin transitions and transformation of molecular structure. However, the precise nature of the associated ultrafast structural dynamics remains elusive, especially in the solid state. Here, we studied a single-crystal SCO material with femtosecond electron diffraction (FED). The unique capability of FED allows us to directly probe atomic motions and to track ultrafast structural changes within a crystal lattice. By monitoring the time-dependent changes of the Bragg reflections, we observed the formation of a photoinduced structure similar to the thermally induced high-spin state...
June 12, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28492076/total-synthesis-of-%C3%AE-indomycinone-and-kidamycinone-by-means-of-two-regioselective-diels-alder-reactions
#16
Thibaud Mabit, Aymeric Siard, Mathilde Pantin, Doumadé Zon, Laura Foulgoc, Drissa Sissouma, André Guingant, Monique Mathé-Allainmat, Jacques Lebreton, François Carreaux, Gilles Dujardin, Sylvain Collet
An efficient access for the synthesis of pluramycinones is described. Total syntheses of racemic γ-indomycinone and kidamycinone were achieved by means of two Diels-Alder reactions. A first Diels-Alder condensation followed by a Stille cross-coupling is used for the elaboration of the desired substituted dienes which will be involved in the second pericyclic reaction with juglone to construct the tetracyclic core of pluramycinones.
May 23, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28487221/neurophysiological-insights-on-flexibility-improvements-through-motor-imagery
#17
Thiago Ferreira Dias Kanthack, Aymeric Guillot, Charalambos Papaxanthis, Théophile Guizard, Christian Collet, Franck Di Rienzo
The efficacy of motor imagery (MI) practice to facilitate muscle stretching remains controversial and the underlying neurophysiological mechanisms unexplored. We evaluated the effects of MI practice during a sit-and-reach task. Healthy participants were randomly assigned to a MI practice (n=15) or Control (n=15) group and completed 2 blocks of 5 sit-and-reach trials. During the first block (B1), participants performed 5 maximal stretching trials of 10s. During the second block (B2), trials were divided into two consecutive parts: i) reproducing the maximum performance of B1 (10s, B2 part 1), and ii) attempting to outperform the maximum performance of B1 (10s, B2 part 2)...
May 6, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28482002/thyroid-function-tests-in-the-reference-range-and-fracture-individual-participant-analysis-of-prospective-cohorts
#18
Carole E Aubert, Carmen Floriani, Douglas C Bauer, Bruno R da Costa, Daniel Segna, Manuel R Blum, Tinh-Hai Collet, Howard A Fink, Anne R Cappola, Lamprini Syrogiannouli, Robin P Peeters, Bjørn O Åsvold, Wendy Pj den Elzen, Robert N Luben, Alexandra P Bremner, Apostolos Gogakos, Richard Eastell, Patricia M Kearney, Mari Hoff, Erin Le Blanc, Graziano Ceresini, Fernando Rivadeneira, André G Uitterlinden, Kay-Tee Khaw, Arnulf Langhammer, David J Stott, Rudi Gj Westendorp, Luigi Ferrucci, Graham R Williams, Jacobijn Gussekloo, John P Walsh, Drahomir Aujesky, Nicolas Rodondi
Context: Hyperthyroidism is associated with increased fracture risk, but it is not clear if lower TSH and higher free thyroxine (FT4) in euthyroid individuals are associated with fracture risk. Objective: To evaluate the association of TSH and FT4 with incident fractures in euthyroid individuals. Design: Individual participant data analysis. Setting: Thirteen prospective cohort studies with baseline examinations between 1981 and 2002...
May 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28472484/adverse-events-while-awaiting-myocardial-revascularization-a-systematic-review-and-meta-analysis
#19
Stuart J Head, Bruno R da Costa, Berend Beumer, Giulio G Stefanini, Fernando Alfonso, Peter M Clemmensen, Jean-Philippe Collet, Jochen Cremer, Volkmar Falk, Gerasimos Filippatos, Christian Hamm, A Pieter Kappetein, Adnan Kastrati, Juhani Knuuti, Philippe Kolh, Ulf Landmesser, Günther Laufer, Franz-Josef Neumann, Dimitrios J Richter, Patrick Schauerte, David P Taggart, Lucia Torracca, Marco Valgimigli, William Wijns, Adam Witkowski, Stephan Windecker, Peter Jüni, Miguel Sousa-Uva
OBJECTIVES: The aim of the current study was to estimate adverse event rates while awaiting myocardial revascularization and review criteria for prioritizing patients. METHODS: A PubMed search was performed on 19 January 2015, to identify English-language, original, observational studies reporting adverse events while awaiting coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). Rates of death, non-fatal myocardial infarction (MI) and emergency revascularization were calculated as occurrence rates per 1000 patient-weeks and pooled using random-effects models...
May 2, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28467926/a-specific-gut-microbiota-dysbiosis-of-type-2-diabetic-mice-induces-glp-1-resistance-through-an-enteric-no-dependent-and-gut-brain-axis-mechanism
#20
Estelle Grasset, Anthony Puel, Julie Charpentier, Xavier Collet, Jeffrey E Christensen, François Tercé, Rémy Burcelin
Glucagon-like peptide-1 (GLP-1)-based therapies control glycemia in type 2 diabetic (T2D) patients. However, in some patients the treatment must be discontinued, defining a state of GLP-1 resistance. In animal models we identified a specific set of ileum bacteria impairing the GLP-1-activated gut-brain axis for the control of insulin secretion and gastric emptying. Using prediction algorithms, we identified bacterial pathways related to amino acid metabolism and transport system modules associated to GLP-1 resistance...
May 2, 2017: Cell Metabolism
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