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https://www.readbyqxmd.com/read/28330651/serial-assessment-of-tissue-precursors-and%C3%A2-progression-of-coronary-calcification-analyzed-by-fusion-of-ivus-and-oct-5-year-follow-up-of-scaffolded-and-nonscaffolded-arteries
#1
Yaping Zeng, Hiroki Tateishi, Rafael Cavalcante, Erhan Tenekecioglu, Pannipa Suwannasom, Yohei Sotomi, Carlos Collet, Shaoping Nie, Hans Jonker, Jouke Dijkstra, Maria D Radu, Lorenz Räber, Dougal R McClean, Robert-Jan van Geuns, Evald H Christiansen, Therese Fahrni, Jacques Koolen, Yoshinobu Onuma, Nico Bruining, Patrick W Serruys
OBJECTIVES: The aim of this study was to assess calcium growth with fused grayscale intravascular ultrasound (IVUS), IVUS-virtual histology, and optical coherence tomography (OCT) from baseline to 5-year follow-up in patients treated with bioresorbable vascular scaffolds. BACKGROUND: IVUS and OCT have individual strengths in assessing plaque composition and volume. Fusion of images obtained using these methods could potentially aid in coronary plaque assessment...
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28329380/subclinical-thyroid-dysfunction-and-cardiovascular-diseases-2016-update
#2
Carmen Floriani, Baris Gencer, Tinh-Hai Collet, Nicolas Rodondi
Subclinical thyroid dysfunction comprises subclinical hypothyroidism (SHypo), defined as elevated thyroid-stimulating hormone (TSH) by normal free thyroxine (FT4), and subclinical hyperthyroidism (SHyper) with decreased or undetectable TSH and normal FT4. Up to 10% of the elderly have SHypo, which is usually asymptomatic. Individual participant data (IPD) analyses of prospective cohort studies from the international Thyroid Studies Collaboration show that SHypo is associated with increased coronary heart disease (CHD) mortality [hazard ratio (HR) 1,58 for TSH ≥ 10 mIU/L, 95% CI 1...
February 27, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28329198/long-term-serial-non-invasive-multislice-computed-tomography-angiography-with-functional-evaluation-after-coronary-implantation-of-a-bioresorbable-everolimus-eluting-scaffold-the-absorb-cohort-b-msct-substudy
#3
Yoshinobu Onuma, Carlos Collet, Robert-Jan van Geuns, Bernard de Bruyne, Evald Christiansen, Jacques Koolen, Pieter Smits, Bernard Chevalier, Dougal McClean, Dariusz Dudek, Stephan Windecker, Ian Meredith, Koen Nieman, Susan Veldhof, John Ormiston, Patrick W Serruys
Aims: Multimodality invasive imaging of the first-in-man cohort demonstrated at 5 years stable lumen dimensions and a low rate of major adverse cardiac events (MACE). However, the long-term non-invasive assessment of this device remains to be documented. The objective was to describe the 72-month multislice computed tomography (MSCT) angiographic and functional findings after the implantation of the second iteration of the fully resorbable everolimus-eluting polymeric scaffold. Methods and results: In the ABSORB Cohort B trial patients with non-complex de novo lesions were treated with second iteration bioresobable vascular scaffold (BVS)...
March 16, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28323452/how-to-manage-plant-biomass-originated-from-phytotechnologies-gathering-perceptions-from-end-users
#4
V Bert, S Neu, I Zdanevitch, W Friesl-Hanl, S Collet, R Gaucher, M Puschenreiter, I Müller, J Kumpiene
A questionnaire survey was carried out in 4 European countries to gather end-user's perceptions of using plants from phytotechnologies in combustion and anaerobic digestion (AD). 9 actors of the wood energy sector from France, Germany and Sweden, and 11 AD platform operators from France, Germany and Austria were interviewed. Questions related to installation, input materials, performed analyses, phytostabilization and phytoextraction. Although the majority of respondents did not know phytotechnologies, results suggested that plant biomass from phytomanaged areas could be used in AD and combustion, under certain conditions...
March 21, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28317793/how-should-i-treat-a-tavi-eligible-patient-with-a-left-ventricular-thrombus-and-rapid-clinical-deterioration
#5
Spyridon Deftereos, Georgios Giannopoulos, Konstantinos Raisakis, Agathi-Rosa Vrettou, Fotios Kolokathis, Achilleas Zacharoulis, Dimitrios Angouras, Dimitrios Alexopoulos, John Lekakis, Holger Eggebrecht, Johannes Lämmer, Nestoras Papadopoulos, Jean-Philippe Collet
No abstract text is available yet for this article.
March 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28315948/-18f-fmiso-pet-study-of-hypoxia-in-gliomas-before-surgery-correlation-with-molecular-markers-of-hypoxia-and-angiogenesis
#6
Lien Bekaert, Samuel Valable, Emmanuèle Lechapt-Zalcman, Keven Ponte, Solène Collet, Jean-Marc Constans, Guénaëlle Levallet, Karim Bordji, Edwige Petit, Pierre Branger, Evelyne Emery, Alain Manrique, Louisa Barré, Myriam Bernaudin, Jean-Sébastien Guillamo
PURPOSE: Hypoxia in gliomas is associated with tumor resistance to radio- and chemotherapy. However, positron emission tomography (PET) imaging of hypoxia remains challenging, and the validation of biological markers is, therefore, of great importance. We investigated the relationship between uptake of the PET hypoxia tracer [18F]-FMISO and other markers of hypoxia and angiogenesis and with patient survival. PATIENTS AND METHODS: In this prospective single center clinical study, 33 glioma patients (grade IV: n = 24, III: n = 3, and II: n = 6) underwent [18F]-FMISO PET and MRI including relative cerebral blood volume (rCBV) maps before surgery...
March 18, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28288873/a-3d-model-of-tumour-angiogenic-microenvironment-to-monitor-hypoxia-effects-on-cell-interactions-and-cancer-stem-cell-selection
#7
Krzysztof Klimkiewicz, Kazimierz Weglarczyk, Guillaume Collet, Maria Paprocka, Alan Guichard, Michal Sarna, Alicja Jozkowicz, Jozef Dulak, Tadeusz Sarna, Catherine Grillon, Claudine Kieda
Tumour microenvironment determines the fate of treatments. Reconstitution of tumour conditions is mandatory for alternative in vitro methods devoted to cancer development and the selection of therapeutic strategies. This work describes a 3D model of melanoma growth in its environment. Introducing means to mimic tumour angiogenesis, which turns on tumour progression, the model shows that melanoma tumour spheroids allow reconstitution of solid tumours with stromal cells. Angiogenesis evidenced the differential recruitment of endothelial cells (EC) from early progenitors (EEPCs) to mature ECs...
March 10, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28284919/nanostructured-monolinolein-miniemulsions-as-delivery-systems-role-of-the-internal-mesophase-on-cytotoxicity-and-cell-internalization
#8
Samuel Guillot, Fabienne Méducin, Kristina Poljak, Virginie Malard, Alexandra Foucault-Collet, Sébastien Serieye, Chantal Pichon
Recent advances in nanoparticle systems for improved drug delivery display a great potential for the administration of active molecules. Here, lipid miniemulsions with various internal nanostructures were loaded with the chemotherapeutic agent Paclitaxel. The goal is to assess the impact of internal structures on their efficiency. Previously the structure, the stability and the physico-chemical properties of those carriers were characterized. Modalities of action were addressed by the evaluation of their effects on the tumor cells viability, their cellular uptake by flow cytometry and confocal microscopy detection of fluorescently labeled nanostructured miniemulsions...
March 8, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28279999/simplified-mortality-score-for-the-intensive-care-unit-sms-icu-protocol-for-the-development-and-validation-of-a-bedside-clinical-prediction-rule
#9
Anders Granholm, Anders Perner, Mette Krag, Peter Buhl Hjortrup, Nicolai Haase, Lars Broksø Holst, Søren Marker, Marie Oxenbøll Collet, Aksel Karl Georg Jensen, Morten Hylander Møller
INTRODUCTION: Mortality prediction scores are widely used in intensive care units (ICUs) and in research, but their predictive value deteriorates as scores age. Existing mortality prediction scores are imprecise and complex, which increases the risk of missing data and decreases the applicability bedside in daily clinical practice. We propose the development and validation of a new, simple and updated clinical prediction rule: the Simplified Mortality Score for use in the Intensive Care Unit (SMS-ICU)...
March 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28277650/emergence-of-hemicryptophanes-from-synthesis-to-applications-for-recognition-molecular-machines-and-supramolecular-catalysis
#10
Dawei Zhang, Alexandre Martinez, Jean-Pierre Dutasta
In the wide area of host-guest chemistry, hemicryptophanes, combining a cyclotribenzylene (or cyclotriveratrylene CTV) unit with another different C3-symmetrical moiety, appears as a recent family of molecular cages. The synthesis and recognition properties of the first hemicryptophane were reported in 1982 by Collet and Lehn, but the very little attention received by this class of host compounds in the 20 years following this first promising result can account for their apparent novelty. Indeed, in the last 10 years hemicryptophanes have aroused growing interest, and new aspects have been developed...
March 9, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28269769/do-hearing-aids-influence-behavioral-and-psychological-symptoms-of-dementia-and-quality-of-life-in-hearing-impaired-alzheimer-s-disease-patients-and-their-caregivers
#11
Arnaud Adrait, Xavier Perrot, Marie-France Nguyen, Marine Gueugnon, Charles Petitot, Lionel Collet, Adeline Roux, Marc Bonnefoy
BACKGROUND: It has been suggested that age-related hearing loss (ARHL) and Alzheimer's disease (AD) are commonly associated. OBJECTIVE: The Alzheimer Disease, Presbycusis and Hearing Aids (ADPHA) clinical trial assessed the influence of hearing aids (HAs) on patients affected by ARHL and AD, as judged by behavioral symptoms and functional abilities, as well as patient and caregiver quality of life (QoL). METHODS: A multicenter double-blind randomized placebo-controlled trial, with a semi-crossover procedure over 12 months, was conducted from 2006 to 2012...
March 2, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28268141/mitigating-risk-of-ankle-valgus-from-ankle-osteochondroma-resection-using-a-transfibular-approach-a-retrospective-study-with-six-years-of-follow-up
#12
Benjamin Appy-Fedida, Elie Krief, François Deroussen, Marie-Christine Plancq, Louis-Michel Collet, Céline Klein, Richard Gouron
To prevent worsening of ankle valgus and functional repercussions, a distal inter-tibiofibular osteochondroma can be removed using a transfibular approach. We evaluated the difference between the preoperative and postoperative tibiotalar tilt at the last follow-up examination and the clinical and radiologic outcomes. We included 10 consecutive ankles that had undergone removal of an osteochondroma using a transfibular approach. The mean patient age was 10.6 years. One ankle was lost to follow-up. The mean postoperative follow-up duration was 5...
March 3, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28253088/association-between-telomere-length-chronic-kidney-disease-and-renal-traits-a-systematic-review
#13
Oluwatoyin I Ameh, Ikechi G Okpechi, Collet Dandara, André-Pascal Kengne
Telomere length (TL) is an important biological variable that can influence a variety of disease-related complex traits as well as host-environment interactions such as drug and nutritional responses. Chronic kidney disease (CKD) is a common global health challenge especially with the currently aging world population. We conducted a PubMed database search according to the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines for systematic reviews. Studies in adults (18 years and above) in which TL was determined and correlated with CKD, renal traits, and function were included, while animal model studies were excluded...
March 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28251302/colleters-in-rubiaceae-from-forest-and-savanna-the-link-between-secretion-and-environment
#14
Fernanda Tresmondi, Yve Canaveze, Elza Guimarães, Silvia Rodrigues Machado
This study aims to investigate colleters' secretory function, on cellular level, in Rubiaceae species from contrasting environments looking to explore the association between secretion and environment. We collected samples from eight species of Rubiaceae growing in forest and savanna having standard-type colleters with diverse histochemistry (hydrophilic, lipophilic and mixed secretions) and processed for both conventional and cytochemical study under transmission electron microscopy (TEM). The standard colleters, although similar in morphology and anatomy, exhibited marked differences on cellular level, especially in the abundance and topology of Golgi bodies, endoplasmic reticulum and plastids when comparing forest and savanna species...
April 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28237734/respective-role-of-surface-electrocardiogram-and-his-bundle-recordings-to-assess-the-risk-of-atrioventricular-block-after-transcatheter-aortic-valve-replacement
#15
N Badenco, C Chong-Nguyen, C Maupain, C Himbert, G Duthoit, X Waintraub, T Chastre, E Gandjbakhch, F Hidden-Lucet, P Le Prince, J-P Collet, R Frank
BACKGROUND: Atrioventricular block (AVB) is common after transcatheter aortic valve replacement (TAVR) and permanent pacemaker (PPM) implantation is needed in up to 30% of patients. Main predictors of long term AVB are electrocardiographic. The purpose of this study is to assess the prognostic value of serial HV intervals measured before and after TAVR to shorten the timing of PPM implantation. METHODS: His bundle recordings were performed before (HV1), immediately after TAVR (HV2) and at day 2 for Edwards Sapien (ES) and 5 for Medtronic CoreValve (CV) (HV3)...
February 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28236769/surgically-treated-oesophageal-cancer-developed-in-a-radiated-field-impact-on-peri-operative-and-long-term-outcomes
#16
Sheraz R Markar, Caroline Gronnier, Arnaud Pasquer, Alain Duhamel, Hélène Behal, Jérémie Théreaux, Johan Gagnière, Gil Lebreton, Cécile Brigand, Bernard Meunier, Denis Collet, Christophe Mariette
BACKGROUND: The objectives of this study were to compare peri-operative and long-term outcomes from oesophageal cancer (EC) (i) that arose in a previously radiated field (ECRF) versus primary (PEC) and among ECRF patients and (ii) radiotherapy-induced (RIEC) versus non-radiotherapy-induced EC (NRIEC). METHODS: Data were collected from 30 European centres from 2000 to 2010. Two thousand four hundred eighty nine EC patients surgically treated were included in the PEC group and 136 in the ECRF group, NRIEC group (n = 61) and RIEC group (n = 75)...
February 22, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28220011/mri-findings-in-collet-sicard-syndrome
#17
Frank J Barbiero, Joachim M Baehring, Robert K Fulbright, Kevin P Becker
No abstract text is available yet for this article.
February 21, 2017: Neurology
https://www.readbyqxmd.com/read/28216663/the-importance-of-pollen-chemistry-in-evolutionary-host-shifts-of-bees
#18
Maryse Vanderplanck, Nicolas J Vereecken, Laurent Grumiau, Fabiana Esposito, Georges Lognay, Ruddy Wattiez, Denis Michez
Although bee-plant associations are generally maintained through speciation processes, host shifts have occurred during evolution. Understanding shifts between both phylogenetically and morphologically unrelated plants (i.e., host-saltation) is especially important since they could have been key processes in the origin and radiation of bees. Probably far from being a random process, such host-saltation might be driven by hidden constraints associated with plant traits. We selected two clades of oligolectic bees (i...
February 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28212919/thrombus-composition-in-sudden-cardiac-death-from-acute-myocardial-infarction
#19
Johanne Silvain, Jean-Philippe Collet, Paul Guedeney, Olivier Varenne, Chandrasekaran Nagaswami, Carole Maupain, Jean-Philippe Empana, Chantal Boulanger, Muriel Tafflet, Stephane Manzo-Silberman, Mathieu Kerneis, Delphine Brugier, Nicolas Vignolles, John W Weisel, Xavier Jouven, Gilles Montalescot, Christian Spaulding
BACKGROUND AND AIM: It was hypothesized that the pattern of coronary occlusion (thrombus composition) might contribute to the onset of ventricular arrhythmia and sudden cardiac death (SCD) in myocardial infarction (MI). METHODS: The TIDE (Thrombus and Inflammation in sudden DEath) study included patients with angiographically-proven acute coronary occlusion as the cause of a ST elevation MI (STEMI) complicated by Sudden Cardiac Death (SCD group) or not (STEMI group)...
February 14, 2017: Resuscitation
https://www.readbyqxmd.com/read/28181585/single-or-dual-antiplatelet-therapy-after-pci
#20
REVIEW
Yosuke Miyazaki, Pannipa Suwannasom, Yohei Sotomi, Mohammad Abdelghani, Karthik Tummala, Yuki Katagiri, Taku Asano, Erhan Tenekecioglu, Yaping Zeng, Rafael Cavalcante, Carlos Collet, Yoshinobu Onuma, Patrick W Serruys
The optimal duration and type of antiplatelet therapy after implantation of a drug-eluting stent (DES) remains uncertain. At the time of the first-in-man implantation of the sirolimus DES in 1999, the protocol-defined dual antiplatelet therapy (DAPT) duration was only 2 months. Subsequently, DAPT duration was extended to 1 year on the basis of anecdotal historical data, and this practice was then incorporated into clinical guidelines. For >1 decade, trialists have sought to compare the safety and efficacy of abbreviated (<6 months) and prolonged (>12 months) DAPT regimens...
February 9, 2017: Nature Reviews. Cardiology
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