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https://www.readbyqxmd.com/read/28346793/early-immune-responses-to-marek-s-disease-vaccines
#1
Mohammad Heidari, Dan Wang, Shuhong Sun
Marek's disease virus (MDV), a highly cell-associated lymphotropic α-herpesvirus, is the causative agent of Marek's disease (MD) in domestic chickens. MDV replicates in chicken cells and establishes a latent infection within CD4(+) T cells. Although MD vaccines have been in use for several decades, the exact mechanism of vaccine-induced protection is unclear. It is believed that the innate immune system plays a role in vaccine-induced immunity against pathogenic strains of MDV. To shed light on the possible function of the innate immunity in vaccine-mediated protection, we investigated the effect of vaccination, Rispens/CVI988, on the activation of cellular components of the innate immune system by analyzing the expression pattern of select immune-related genes in the cecal tonsils (CT) and duodenum of two MD-susceptible and MD-resistant chicken lines at 3, 5, and 10 days postvaccination (dpv)...
March 27, 2017: Viral Immunology
https://www.readbyqxmd.com/read/28343217/contribution-of-hyoid-and-tonsillar-procedures-to-outcome-in-multilevel-surgery-for-obstructive-sleep-apnea-syndrome
#2
Nora Tetter, Kurt Tschopp
BACKGROUND/OBJECTIVE: In multilevel surgery for obstructive sleep apnea (OSA), the contribution of distinct operative steps is still unclear. The aim of the present study is to retrospectively compare different combinations of multilevel surgeries in order to estimate the contribution of hyoid and tonsillar procedures to the outcome. METHODS: A total of 45 patients were selected in a retrospectively matched case-control study from a database of patients who underwent surgery for OSA at our institution: group A (n = 15) had hyoid suspension, tonsillectomy, and radiofrequency-assisted uvulopalatoplasty (RAUP); group B (n = 15) had hyoid pharyngoplasty with resection of the hyoid body and preepiglottic fat tissue, tonsillectomy, and RAUP; and group C (n = 15) had hyoid suspension and RAUP but no tonsillectomy, because the tonsils had already been removed...
March 25, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28343210/periodic-fever-aphthous-stomatitis-pharyngitis-and-cervical-adenitis-pfapa-syndrome-in-children
#3
Vira B Semianchuk
INTRODUCTION: Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome refers to a group of primary immunodeficiencies, namely autoinflammatory diseases. Most pediatricians and otolaryngologists do not suspect PFAPA syndrome when treating recurrent pharyngitis (according to Ukrainian classification - tonsillitis) and stomatitis. Therefore, patients with a given syndrome receive unnecessary treatment (antibiotic therapy or antiviral drugs) and the diagnosis is made late...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28342482/treatment-outcomes-in-veterans-with-hpv-positive-head-and-neck-cancer
#4
Aaron J Feinstein, Sophie G Shay, Elena Chang, Michael S Lewis, Marilene B Wang
OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) caused by the human papilloma virus (HPV) has an improved prognosis relative to HPV-negative tumors. Patients with HPV-positive disease may benefit from different treatment modalities in order to optimize survival and quality of life. We sought to investigate HPV-positive HNSCC within the military veteran population, and analyze the role of treatment modality in outcomes of patients with HPV-positive and HPV-negative tumors. METHODS: Patients diagnosed with HNSCC between January 1, 2010 and December 31, 2014 at one regional veterans health center were retrospectively examined...
March 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28339714/effect-of-whole-yeast-cell-product-supplementation-citristim%C3%A2-on-immune-responses-and-cecal-microflora-species-in-pullet-and-layer-chickens-during-an-experimental-coccidial-challenge
#5
Ashley D Markazi, Victor Perez, Mamduh Sifri, Revathi Shanmugasundaram, Ramesh K Selvaraj
Three separate experiments were conducted to study the effects of whole yeast cell product supplementation in pullets and layer hens. Body weight gain, fecal and intestinal coccidial oocyst counts, cecal microflora species, cytokine mRNA amounts, and CD4+ and CD8+ T-cell populations in the cecal tonsils were analyzed following an experimental coccidial infection. In Experiment I, day-old Leghorn layer chicks were fed 3 experimental diets with 0, 0.1, or 0.2% whole yeast cell product (CitriStim®, ADM, Decatur, IL)...
February 21, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339449/reversal-of-progressive-conscious-disturbance-with-epidural-blood-patch-for-cerebrospinal-fluid-leakage-at-c2-level
#6
Yi-Chen Lai, Yuan-Yi Chia, Wei-Hung Lien
Intracranial hypotension syndrome (IHS) is generally caused by cerebrospinal fluid (CSF) leakage. Complications include bilateral subdural hygroma or haematoma and herniation of the cerebellar tonsils. Epidural blood patch (EBP) therapy is indicated if conservative treatment is ineffective. We reported the case of a 46-year-old man with a history of postural headache and dizziness. The patient was treated with bed rest and daily hydration with 2000 mL of fluid for 2 weeks. However, dizziness and headache did not resolve, and he became drowsy and disoriented with incomprehensible speech...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28338813/antibiotic-prescribing-for-acute-respiratory-infections-in-children-in-jordan
#7
Mera A Ababneh, Sayer I Al-Azzam, Rawan Ababneh, Abeer M Rababa'h, Saddam Al Demour
Background: Most acute respiratory infections (ARIs) in children are due to viral etiology; however, over-prescribing of antibiotics for ARIs is common. The aim of this investigation was to identify antibiotic prescribing prevalence for children with ARIs and to identify predictors of broad-spectrum antibiotic prescribing. Methods: This was a prospective cross sectional study in a sample of ambulatory care settings in Jordan. Children (<18 years) presenting with ARIs were assessed in terms of patient's demographics, antibiotic prescription and clinical diagnosis...
February 24, 2017: International Health
https://www.readbyqxmd.com/read/28337533/incidence-of-second-surgery-following-pediatric-adenotonsillar-surgery-a-population-based-cohort-study
#8
Ola Sunnergren, Erik Odhagen, Joacim Stalfors
The aim of the study is to evaluate the incidence and risk factors of a second surgery of the adenoids or tonsils for hypertrophy in children who have already undergone surgery for the same condition. This is a retrospective study (2004-2013) based on data from the National patient registry in Sweden. A total of 41,401 children underwent a first surgery of the adenoids or tonsils during the studied period. The most commonly performed (first) surgical procedure was adenoidectomy followed by adenotonsillotomy, adenotonsillectomy, tonsillotomy, and tonsillectomy...
March 23, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28330788/oral-cancer-characteristics-in-france-descriptive-epidemiology-for-early-detection
#9
K Jéhannin-Ligier, O Dejardin, B Lapôtre-Ledoux, S Bara, G Coureau, P Grosclaude, E Marrer, F Molinié, B Trétarre, M Velten, A-S Woronoff, M Colonna, A V Guizard
Despite the frequency and lethality of oral cancers in France, there are no detailed general population data regarding the characteristics of these patients to fuel the public health authorities' reflections about early detection policies. Thus, the objective of this study was to determine, in the general population, the characteristics of both patients and tumours at the time of the diagnosis. A high-resolution, population-based study using 13 French registries was conducted on 1089 tumours diagnosed in 2010...
February 24, 2017: J Stomatol Oral Maxillofac Surg
https://www.readbyqxmd.com/read/28328605/unusual-association-cerebral-arteriovenous-malformation-and-chiari-type-i-malformation
#10
Hayri Ogul, Mecit Kantarci
Cerebral arteriovenous malformation (AVM) is a common type of cerebral vascular malformation. The imaging findings are enlarged vessels, thrombosed sinuses, and hemorrhage or gliosis on adjacent brain parenchyma. Magnetic resonance (MR) imaging can be used safely for diagnosis. Chiari type I malformation is characterized by a caudal descent of the cerebellar tonsil. Coincidence of cerebral AVM and Chiari type I malformation is very rare. In this paper, the authors report MR imaging findings of a patient with coincidence of cerebral AVM and Chiari type I malformation...
March 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28320866/adenotonsillotomy-versus-adenotonsillectomy-in-pediatric-obstructive-sleep-apnea-an-rct
#11
Anna Borgström, Pia Nerfeldt, Danielle Friberg
BACKGROUND: Adenotonsillectomy (ATE) is a well-established and effective treatment of pediatric obstructive sleep apnea (OSA). In recent years, a more conservative method, adenotonsillotomy (ATT), has gained popularity because it is associated with less postoperative morbidity. Yet no previous randomized study has compared these 2 methods regarding their effectiveness in treating pediatric OSA in terms of polysomnographic data, which was the primary aim of this study. The hypothesis was that ATT is noninferior to ATE after 1 year...
March 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28318453/helicobacter-pylori-in-the-tonsillar-tissue-a-possible-association-with-chronic-tonsillitis-and-laryngopharyngeal-reflux
#12
N Siupsinskiene, I Katutiene, V Jonikiene, D Janciauskas, S Vaitkus
OBJECTIVE: To identify Helicobacter pylori infection in tonsillar tissue samples from patients undergoing tonsillectomy for chronic tonsillitis versus tonsillar hypertrophy, and to assess the possible relationships between H pylori and patients' sociodemographic data and laryngopharyngeal reflux. METHODS: In this prospective study, 97 patients who underwent tonsillectomy were divided into the following 2 groups: patients with chronic tonsillitis (n = 62) and patients with tonsillar hypertrophy (control group; n = 35)...
March 20, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28315933/coblation-tonsillectomy-a-systematic-review-and-descriptive-analysis
#13
Christopher Metcalfe, Jameel Muzaffar, Charles Daultrey, Christopher Coulson
Coblation is one of the more recent techniques for tonsillectomy; however, it remains unclear whether it exhibits any benefit or increased risk when compared to other techniques. This review provides an updated assessment of coblation tonsillectomy and how it compares to other tonsillectomy techniques. Systematic review and descriptive analysis of published literature. Electronic searches of MEDLINE, EMBASE, Web of Science and the Cochrane Database were performed. We included all randomized control trials comparing coblation tonsillectomy (not 'tonsillotomy') with any other tonsillectomy technique...
March 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28314977/isolated-vestibular-syndromes-due-to-brainstem-and-cerebellar-lesions
#14
Sung-Hee Kim, Hyo Jung Kim, Ji-Soo Kim
Dizziness/vertigo is the most common symptoms of posterior circulation strokes. Isolated vestibular symptoms and signs without other neurologic deficits have been found in infarctions involving the brainstem and cerebellum. In the brainstem, infarctions responsible for isolated vestibular syndrome are usually restricted to the dorsal portion that contains the vestibular nucleus and the nucleus prepositus hypoglossi. Cerebellar lesions confined to the flocculus, tonsil, and nodulus also produce isolated vertigo and imbalance...
March 17, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28306724/respiratory-dna-viruses-are-undetectable-in-nasopharyngeal-secretions-from-adenotonsillectomized-children
#15
Ronaldo Bragança Martins, Lucas Penna Rocha, Mirela Moreira Prates, Talita Bianca Gagliardi, Balduino Biasoli, Marcelo Junqueira Leite, Guilherme Buzatto, Miguel Angelo Hyppolito, Davi Casale Aragon, Edwin Tamashiro, Fabiana Cardoso Pereira Valera, Eurico Arruda, Wilma Terezinha Anselmo-Lima
Respiratory viruses are frequently detected in association with chronic tonsillar hypertrophy in the absence of symptoms of acute respiratory infection (ARI). The present analysis was done in follow-up to a previous clinical study done by this same group. Nasopharyngeal washes (NPWs) were obtained from 83 of 120 individuals at variable times post adenotonsillectomy, in the absence of ARI symptoms. A look back at virus detection results in NPWs from the same 83 individuals at the time of tonsillectomy revealed that 73...
2017: PloS One
https://www.readbyqxmd.com/read/28304006/tonsillar-solitary-fibrous-tumour-a-interesting-rare-case
#16
Gulay Bulut, Remzi Erten, Ayse Oter Almali, Mehmet Deniz Bulut, Irfan Bayram
A solitary fibrous tumour (SFT) is a rare mesenchymal tumour that frequently originates in the mesothelium-covered surfaces, such as the pleura and peritoneum. It may develop in various body parts, including the head and neck. These tumours may arise in several different patterns, which results in difficulties in diagnosing them. This case is a solitary tumour developing from the palatine tonsil in a 17-year-old male patient; it is the second case in the literature. The tumour has the histopathological characteristics of a patternless pattern, a slight pleomorphism, and a composition of hypercellular and hypocellular sites...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28299210/radiographic-enlargement-of-mandibular-canal-as-an-extranodal-primary-non-hodgkin-s-lymphoma-early-sign-in-an-asymptomatic-patient
#17
Luciana Munhoz, Felipe Pereira Marcos Marsan, Emiko Saito Arita
Non-Hodgkin's lymphoma (NHL) is a lymphoproliferative disorder, from a subgroup of heterogeneous hematologic malignancies; the term "extranodal" refers to malignant involvement of tissues other than lymph nodes, tonsils, spleen, pharyngeal lymphatic ring, or thymus. Only 0.6% of all NHL are at mandible alone, and it may involve the inferior alveolar canal. We describe a case of bilateral enlargement of the mandibular canal without symptomatology, which was shown in a panoramic radiograph and cone beam computed tomography in a rehabilitation routine exam, as an early sign of primary extranodal NHL...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28296741/a-cyclin-d1-positive-diffuse-large-b-cell-lymphoma-of-germinal-center-b-cell-like-subtype-in-the-right-tonsil-a-rare-case-report
#18
Changrui Jiang, Xiuying Shi, Chuifeng Fan
INTRODUCTION: Cyclin D1-positive tumor cells are commonly found in mantle cell lymphoma but they are very rare in diffuse large B-cell lymphoma. CLINICAL FINDINGS/PATIENT CONCERNS: Here we present a rare case of cyclin D1-positive diffuse large B-cell lymphoma in the right tonsil of a 50-year-old man. Computed tomographic imaging detected a mass, about 2.5 cm × 1.8 cm in size, in the left side of the oropharynx. DIAGNOSES: Microscopically, the tumor cells were located under the pharyngeal mucosa and diffusely arranged...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28296378/-type-i-chiari-malformation-associated-with-cerebellar-atrophy-case-report
#19
Luis Rafael Moscote-Salazar, Willem Guillermo Calderón-Miranda, Hernando Raphael Alvis-Miranda, Ángel Lee-Aguirre, Gabriel Alcalá-Cerra
Chiari malformation is characterized by caudal displacement of the cerebellar tonsils that penetrate into the spinal canal through the foramen magnum, achieving reach the atlas or axis. trunk and any drop of the fourth ventricle is observed. Typically is seen in young adults. In some cases scoliosis and Syringomyelic cavities may occur. The authors present (as far as they know) the first case in the literature with long term follow-up, of a caucasian woman with an unusual form of cerebellar atrophy and Chiari Type I malformation, suffering from weakness in his upper and lower extremities with rapidly progression...
March 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28293975/human-papillomavirus-prevalence-in-mouthwashes-of-patients-undergoing-tonsillectomy-shows-dominance-of-hpv69-without-the-corresponding-finding-in-the-tonsils
#20
Nathalie Grün, Wilbert Mbuya, Anders Ternhag, Torbjörn Ramqvist, Alexander Ahlberg, Mattias Jangard, Tina Dalianis, Lalle Hammarstedt-Nordenvall
BACKGROUND: The role of human papillomavirus (HPV) in tonsillar squamous cell carcinomas (TSCC) is of interest, since a considerable proportion of TSCC in Sweden and other Western countries is HPV positive. Nevertheless, the natural history of HPV in normal tonsils, and the progression from localized infection to pre-malignant lesion to cancer are poorly understood. The aim of this study was to investigate whether HPV types found in mouthwash samples correlated to those in tonsillar tissue from the same individuals undergoing tonsillectomy...
March 15, 2017: Infectious Diseases
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