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https://www.readbyqxmd.com/read/28214597/classification-criteria-versus-physician-s-opinion-for-considering-a-patient-with-inflammatory-back-pain-as-suffering-from-spondyloarthritis
#1
Pierre Gazeau, Divi Cornec, Marie Agnes Timsit, Maxime Dougados, Alain Saraux
OBJECTIVE: To assess agreement among methods for classifying patients with inflammatory back pain [IBP] after a 2-year follow up. METHODS: Patients with IBP in the French nationwide, longitudinal, prospective cohort DESIR were classified after 2 years based on imaging findings, rheumatologist's confidence in a diagnosis of spondyloarthritis, three classification criteria sets [axial Assessment of Spondyloarthritis international Society (ASAS), European Spondylarthropathy Study Group (ESSG), and Amor] and treatment [TNFα antagonists]...
February 15, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28214039/beyond-ecosystem-services-valuing-the-invaluable
#2
REVIEW
Richard M Gunton, Eline N van Asperen, Andrew Basden, David Bookless, Yoseph Araya, David R Hanson, Mark A Goddard, George Otieno, Gareth O Jones
The ecosystem services framework (ESF) is advantageous and widely used for itemising and quantifying ways in which humans benefit from natural places. However, it suffers from two important problems: (i) incoherence of definitions and (ii) a narrow approach to valuation, inadequate to represent the full range of human motives for conservation and the diverse interests of different stakeholders. These shortcomings can lead to a range of problems including double-counting, blind spots and unintended consequences...
February 14, 2017: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/28213603/women-s-experiences-with-cervical-cancer-screening-in-a-colposcopy-referral-clinic-in-cape-town-south-africa-a-qualitative-analysis
#3
Mariette Momberg, Matthys H Botha, Frederick H Van der Merwe, Jennifer Moodley
OBJECTIVE: The aim of this study was to explore and understand women's experience with cervical cancer screening and with the referral pathways for abnormal Papanicolau (Pap) smears. DESIGN AND SETTING: Focus group discussions were conducted with first time colposcopy clinic attendees at a tertiary hospital colposcopy clinic in Cape Town, South Africa during November 2014. A thematic analysis was conducted to identify key themes. Initial coding categories were drawn from the interview guide...
February 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28210521/the-right-to-die-in-chronic-disorders-of-consciousness-can-we-avoid-the-slippery-slope-argument
#4
REVIEW
Rocco Salvatore Calabrò, Antonino Naro, Rosaria De Luca, Margherita Russo, Lory Caccamo, Alfredo Manuli, Alessia Bramanti, Placido Bramanti
Managing individuals with chronic disorders of consciousness raises ethical questions about the appropriateness of maintaining life-sustaining treatments and end-of-life decisions for those who are unable to make decisions for themselves. For many years, the positions fostering the "sanctity" of human life (i.e., life is inviolable in any case) have led to maintaining life-sustaining treatments (including artificial nutrition and hydration) in patients with disorders of consciousness, allowing them to live for as long as possible...
November 2016: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/28210365/who-are-the-most-influential-emergency-physicians-on-twitter
#5
Jeff Riddell, Alisha Brown, Ivor Kovic, Joshua Jauregui
INTRODUCTION: Twitter has recently gained popularity in emergency medicine (EM). Opinion leaders on Twitter have significant influence on the conversation and content, yet little is known about these opinion leaders. We aimed to describe a methodology to identify the most influential emergency physicians (EP) on Twitter and present a current list. METHODS: We analyzed 2,234 English-language EPs on Twitter from a previously published list of Twitter accounts generated by a snowball sampling technique...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28210202/mechanisms-and-effects-of-transcranial-direct-current-stimulation
#6
James Giordano, Marom Bikson, Emily S Kappenman, Vincent P Clark, H Branch Coslett, Michael R Hamblin, Roy Hamilton, Ryan Jankord, Walter J Kozumbo, R Andrew McKinley, Michael A Nitsche, J Patrick Reilly, Jessica Richardson, Rachel Wurzman, Edward Calabrese
The US Air Force Office of Scientific Research convened a meeting of researchers in the fields of neuroscience, psychology, engineering, and medicine to discuss most pressing issues facing ongoing research in the field of transcranial direct current stimulation (tDCS) and related techniques. In this study, we present opinions prepared by participants of the meeting, focusing on the most promising areas of research, immediate and future goals for the field, and the potential for hormesis theory to inform tDCS research...
January 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/28209175/effectiveness-of-topical-silicone-gel-and-pressure-garment-therapy-for-burn-scar-prevention-and-management-in-children-study-protocol-for-a-randomised-controlled-trial
#7
Jodie Wiseman, Megan Simons, Roy Kimble, Robert Ware, Steven McPhail, Zephanie Tyack
BACKGROUND: Abnormal scar development following burn injury can cause substantial physical and psychological distress to children and their families. Common burn scar prevention and management techniques include silicone therapy, pressure garment therapy, or a combination of both. Currently, no definitive, high-quality evidence is available for the effectiveness of topical silicone gel or pressure garment therapy for the prevention and management of burn scars in the paediatric population...
February 16, 2017: Trials
https://www.readbyqxmd.com/read/28208330/heterogeneous-out-of-equilibrium-nonlinear-q-voter-model-with-zealotry
#8
Andrew Mellor, Mauro Mobilia, R K P Zia
We study the dynamics of the out-of-equilibrium nonlinear q-voter model with two types of susceptible voters and zealots, introduced in Mellor et al. [Europhys. Lett. 113, 48001 (2016)EULEEJ0295-507510.1209/0295-5075/113/48001]. In this model, each individual supports one of two parties and is either a susceptible voter of type q_{1} or q_{2}, or is an inflexible zealot. At each time step, a q_{i}-susceptible voter (i=1,2) consults a group of q_{i} neighbors and adopts their opinion if all group members agree, while zealots are inflexible and never change their opinion...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28203449/a-cost-utility-analysis-of-different-antiviral-medicine-regimens-in-patients-with-chronic-hepatitis-c-virus-genotype-1-infection
#9
Seyed Moayed Alavian, Shekoufeh Nikfar, Abbas Kebriaeezadeh, Farhad Lotfi, Ehsan Sanati, Mohsen Rezaei Hemami, Khosro Keshavarz
BACKGROUND: Despite the introduction of new drug regimens with high effectiveness for the hepatitis C virus (HCV) patients, especially in HCV genotype 1, no cost-effectiveness study on the selection of the superior drug strategy in Iran has been conducted yet. OBJECTIVES: This study is aimed to assess the cost-effectiveness of the three drug regimens of pegylated interferon and ribavirin (PR), sofosbuvir (SOF) + PR and ledipasvir and sofosbuvir (LDV/SOF) in patients with HCV genotype 1 in Iran in the year 2014...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28202426/integrated-platform-for-home-services-using-new-products-and-services-for-senior-citizens-call-cnav-carsat-2015
#10
Michel Noguès, Daniel Laune, Delphine Paccard, Anne-Laure Coupet, Justine Millot-Keurinck, Narjis Bototo, Marine Bertrand, Jean Bousquet
This project is part of: i) the risks of ageing prevention policy of the French retirement and occupational health insurance agency of Languedoc Roussillon (Carsat-LR) and ii) the European innovation partnership on active and healthy ageing (EIP on AHA). It aims to support senior citizens who live independently and have been identified at risk of frailty on a social or health level. The purpose is to increase legibility as well as technical and financial access to innovations for vulnerable seniors who are remote from the digital era, through a multiservice user-friendly platform...
February 15, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28194490/ranula-current-concept-of-pathophysiologic-basis-and-surgical-management-options
#11
Daniel Kokong, Augustine Iduh, Ikechukwu Chukwu, Joyce Mugu, Samuel Nuhu, Sule Augustine
BACKGROUND: There is no consensus opinion on a definitive surgical management option for ranulas to curtail recurrence, largely from the existing gap in knowledge on the pathophysiologic basis. AIM: To highlight the current scientific basis of ranula development that informed the preferred surgical approach. DESIGN: Retrospective cohort study. SETTING: Public Tertiary Academic Health Institution. METHOD: A 7-year 7-month study of ranulas surgically managed at our tertiary health institution was undertaken-June 1, 2008-December 31, 2015-from case files retrieved utilising the ICD-10 version 10 standard codes...
February 13, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28190947/acceptability-of-a-positive-parenting-programme-on-a-mother-and-baby-unit-q-methodology-with-staff
#12
Hannah Butler-Coyne, Dougal Hare, Samantha Walker, Angelika Wieck, Anja Wittkowski
The Baby Triple P Positive Parenting Programme, a new addition to the established Triple P programmes, is currently being considered for a trial in a Mother and Baby Unit with the aim of exploring its benefits to mothers presenting with severe mental illness. The aim of the current study was to investigate staff views of the acceptability and feasibility of a parenting programme such as the Baby Triple P Positive Parenting Programme in a Mother and Baby Unit. Q-methodology, using an 88-item Q-sort, was employed to explore the opinions of 16 staff working in a Mother and Baby Unit in the North West of England...
2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/28188364/a-survey-of-pulmonary-arteriovenous-malformation-screening-management-and-follow-up-in-hereditary-hemorrhagic-telangiectasia-centers-of-excellence
#13
Jeffrey Forris Beecham Chick, Shilpa N Reddy, Reed E Pyeritz, Scott O Trerotola
PURPOSE: To determine current practice regarding screening, management, and follow-up of pulmonary arteriovenous malformations (PAVMs), particularly those with feeding arteries <3 mm in diameter, in those patients with hereditary hemorrhagic telangiectasia (HHT) at HHT Centers of Excellence. MATERIALS AND METHODS: A 32-question survey focusing on PAVM screening, management, and follow-up was sent to 147 participants at HHT Centers worldwide. RESULTS: Thirty-three responses were received (22%); 60% from interventional radiologists and 20% from pulmonologists; 67% from the USA, 21% European, and 6% Asian...
February 10, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28185587/local-self-governance-in-health-a-study-of-it-s-functioning-in-odisha-india
#14
Bhuputra Panda, Sanjay P Zodpey, Harshad P Thakur
BACKGROUND: Local decision making is linked to several service quality improvement parameters. Rogi Kalyan Samitis (RKS) at peripheral decision making health units (DMHU) are composite bodies that are mandated to ensure accountability and transparency in governance, improve quality of services, and facilitate local responsiveness. There is scant literature on the nature of functioning of these institutions in Odisha. This study aimed to assess the perception of RKS members about their roles, involvement and practices with respect to local decision making and management of DMHUs; it further examined perceptual and functional differences between priority and non-priority district set-ups; and identified predictors of involvement of RKS members in local governance of health units...
October 31, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/28185581/does-decentralization-influence-efficiency-of-health-units-a-study-of-opinion-and-perception-of-health-workers-in-odisha
#15
Bhuputra Panda, Harshad P Thakur, Sanjay P Zodpey
BACKGROUND: Health systems in low and middle income countries are struggling to improve efficiency in the functioning of health units of which workforce is one of the most critical building blocks. In India, Rogi Kalyan Samiti (RKS) was established at every health unit as institutions of local decision making in order to improve productive efficiency and quality. Measuring efficiency of health units is a complex task. This study aimed at assessing the perception (opinion and satisfaction) of health workers about influence of RKS on improving efficiency of peripheral decision making health units (DMHU); examining differences between priority and non-priority set-ups; identifying predictors of satisfaction at work; and discussing suggestions to improve performance...
October 31, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/28183317/practical-guide-to-exocrine-pancreatic-insufficiency-breaking-the-myths
#16
EDITORIAL
Maarten R Struyvenberg, Camilia R Martin, Steven D Freedman
BACKGROUND: Exocrine pancreatic insufficiency (EPI) is characterized by a deficiency of exocrine pancreatic enzymes, resulting in malabsorption. Numerous conditions account for the etiology of EPI, with the most common being diseases of the pancreatic parenchyma including chronic pancreatitis, cystic fibrosis, and a history of extensive necrotizing acute pancreatitis. Treatment for EPI includes dietary management, lifestyle changes (i.e., decrease in alcohol consumption and smoking cessation), and pancreatic enzyme replacement therapy...
February 10, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28178960/ultrasound-and-dynamic-functional-imaging-in-vascular-cognitive-impairment-and-alzheimer-s-disease
#17
REVIEW
Branko Malojcic, Panteleimon Giannakopoulos, Farzaneh A Sorond, Elsa Azevedo, Marina Diomedi, Janja Pretnar Oblak, Nicola Carraro, Marina Boban, Laszlo Olah, Stephan J Schreiber, Aleksandra Pavlovic, Zsolt Garami, Nantan M Bornstein, Bernhard Rosengarten
BACKGROUND: The vascular contributions to neurodegeneration and neuroinflammation may be assessed by magnetic resonance imaging (MRI) and ultrasonography (US). This review summarises the methodology for these widely available, safe and relatively low cost tools and analyses recent work highlighting their potential utility as biomarkers for differentiating subtypes of cognitive impairment and dementia, tracking disease progression and evaluating response to treatment in various neurocognitive disorders...
February 9, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28176221/pegvisomant-in-acromegaly-an-update
#18
REVIEW
A Giustina, G Arnaldi, F Bogazzi, S Cannavò, A Colao, L De Marinis, E De Menis, E Degli Uberti, F Giorgino, S Grottoli, A G Lania, P Maffei, R Pivonello, E Ghigo
BACKGROUND: In 2007, we published an opinion document to review the role of pegvisomant (PEG) in the treatment of acromegaly. Since then, new evidence emerged on the biochemical and clinical effects of PEG and on its long-term efficacy and safety. AIM: We here reviewed the emerging aspects of the use of PEG in clinical practice in the light of the most recent literature. RESULTS: The clinical use of PEG is still suboptimal, considering that it remains the most powerful tool to control IGF-I in acromegaly allowing to obtain, with a pharmacological treatment, the most important clinical effects in terms of signs and symptoms, quality of life and comorbidities...
February 7, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28174218/knowledge-and-opinions-of-veterinary-students-in-italy-toward-animal-welfare-science-and-law
#19
D Magnani, N Ferri, A Dalmau, S Messori
Animal welfare (AW) is a growing concern worldwide and veterinary students are expected to demonstrate a high degree of professional interest in the welfare of animals. However, previous studies have highlighted gaps in the teaching of AW teaching in different countries, possibly impairing veterinary competency in the area. This survey aimed to assess the opinions of Italian veterinary students towards AW, as well as their knowledge on the issue. Questions were divided into different sections, investigating the definition of, and information on, AW, knowledge about AW legislation, and the level of tolerance towards AW in regard to the use of animals for different purposes...
February 7, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28173981/leveraging-natural-variance-towards-enhanced-understanding-of-phytochemical-sunscreens
#20
REVIEW
Takayuki Tohge, Alisdair R Fernie
The dependency of plants on sunlight renders exposure to UV a constant hazard. Light of this wavelength is damaging to proteins, RNA, and DNA, with damage to the latter resulting in a high mutagenic potential. To acclimate to environmental changes in light wavelengths and intensity, plants accumulate the production of UV-B-protectant phytochemicals, such as flavonoids and vitamins. Here, we review current and emerging knowledge concerning the biochemical response of plants to UV-B exposure. We additionally outline our opinion that the adoption of broad natural variance represents a powerful strategy by which to identify both novel UV-B-relevant metabolites and the genes regulating their abundance...
February 4, 2017: Trends in Plant Science
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