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https://www.readbyqxmd.com/read/28240001/polycystic-ovary-syndrome-pcos-diagnostic-criteria-and-amh
#1
Majid Bani Mohammad, Abbas Majdi Seghinsara
The polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and a notable proportion of women of reproductive age are affected. It may constitute a risk factor for cancer development. Different factors could result in different manifestations and many of these are related to predispositions. It is essential to establish criteria to achieve an exact diagnosis of PCOS, especially among adolescent patients because of the overlap between features of PCO syndrome and physiological findings in puberty...
1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28239958/differential-sex-effects-of-systolic-blood-pressure-and-ldl-c-on-type-2-diabetes-life-course-data-from-the-bogalusa-heart-study
#2
Benjamin D Pollock, Wei Chen, Emily W Harville, Tian Shu, Vivian Fonseca, Franck Mauvais-Jarvis, Tanika N Kelly, Lydia A Bazzano
BACKGROUND: There may be sex-specific cardiometabolic mechanisms early in life that affect the development of type 2 diabetes (T2DM) through mid-adulthood. Yet, there have been few studies examining whether early life-course interactions between cardiometabolic risk factors and sex are associated with incident T2DM. METHODS: We followed n = 7,725 children from the Bogalusa Heart Study through mid-adulthood to examine whether low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), body mass index (BMI), or systolic blood pressure (SBP) differentially impact the risk of T2DM for females versus males...
February 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28239923/we-know-that-horses-sweat-and-men-perspire-but-do-ladies-merely-glow
#3
Daniel Gagnon
For some time, the euphemism "horses sweat, men perspire, but ladies merely glow" was scientifically supported. Initial studies examining gender differen0063es in sweat production generally observed that women sweat less than men during heat exposure (i.e. they merely glow). This article is protected by copyright. All rights reserved.
February 26, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28239919/large-multicentre-pilot-randomised-controlled-trial-testing-a-low-cost-tailored-self-help-smoking-cessation-text-message-intervention-for-pregnant-smokers-miquit
#4
Felix Naughton, Sue Cooper, Katharine Foster, Joanne Emery, Jo Leonardi-Bee, Stephen Sutton, Matthew Jones, Michael Ussher, Rachel Whitemore, Matthew Leighton, Alan Montgomery, Steve Parrott, Tim Coleman
AIMS: To estimate the effectiveness of pregnancy smoking cessation support delivered by SMS text message and key parameters needed to plan a definitive trial. DESIGN: Multicentre, parallel-group, single-blinded, individual randomised controlled trial SETTING: 16 antenatal clinics in England. PARTICIPANTS: 407 participants were randomised to the intervention (n = 203) or usual care (n = 204). Eligible women were <25 weeks gestation, smoked at least 1 daily cigarette (>5 pre-pregnancy), were able to receive and understand English SMS texts and were not already using text-based cessation support...
February 26, 2017: Addiction
https://www.readbyqxmd.com/read/28239917/decrease-in-mortality-of-adult-epilepsy-patients-since-1980-lessons-learned-from-a-hospital-based-cohort
#5
C A Granbichler, W Oberaigner, G Kuchukhidze, J-P Ndayisaba, A Ndayisaba, A Taylor, G Bauer, G Luef, E Trinka
BACKGROUND AND PURPOSE: Data on mortality in patients with epilepsy have been available since the 1800s. They consistently show a 2-3-fold increase compared to the general population. Despite major advances in diagnostic tools and treatment options, there is no evidence for a decrease in premature deaths. The temporal trend of mortality in a hospital-based epilepsy cohort over three decades was assessed. METHODS: A hospital-based incidence cohort was recruited from a specialized epilepsy outpatient clinic at Innsbruck Medical University between 1980 and 2007, divided by decade into three cohorts and followed for 5 years after initial epilepsy diagnosis...
February 27, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28239799/the-consistency-of-myocardial-strain-derived-from-heart-deformation-analysis
#6
Eric J Keller, Shanna Fang, Kai Lin, Benjamin H Freed, Peter M Smith, Bruce S Spottiswoode, Rachel Davids, Maria Carr, Marie-Pierre Jolly, Michael Markl, James C Carr, Jeremy D Collins
The purpose of this study was to assess the consistency of semi-automated myocardial strain analysis by prototype software across field strengths, temporal resolutions, and examinations. 35 volunteers (48 ± 13 years; 20% women) and 25 patients (54 ± 12 years; 44% women) without significant cardiac dysfunction underwent cine cardiac magnetic resonance imaging (CMR) at 1.5 T with a temporal resolution of 39.2 msec. 34 subjects also underwent imaging at 3.0 T; 16 had repeat examinations within 14 days; and 9 underwent CMR with temporal resolutions of 12...
February 26, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28239797/characteristics-of-multipotent-mesenchymal-stromal-cells-isolated-from-the-endometrium-and-endometriosis-lesions-of-women-with-malformations-of-the-internal-reproductive-organs
#7
A M Savilova, K N Farkhat, M N Yushina, Yu V Rudimova, Z N Makiyan, L V Adamyan
We isolated and characterized cell cultures from eutopic endometrium and endometriotic lesions of women with malformations of the internal reproductive organs. The cells had fibroblast-like shape and intensively expressed CD90, CD73, CD105, CD44, CD146, and CD117 and were capable of induced adipogenic and osteogenic differentiation in vitro. The obtained cultures exhibited properties of multipotent mesenchymal stromal cells; at the same time, they demonstrated in vitro immunophenotypic differences from cell cultures of eutopic and ectopic endometrium of women without developmental abnormalities, which suggests their functional difference...
February 27, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28239783/effect-of-thp-1-cells-on-the-formation-of-vascular-tubes-by-endothelial-ea-hy926-cells-in-the-presence-of-placenta-secretory-products
#8
T Yu Lvova, K L Belyakova, S A Sel'kov, D I Sokolov
We studied the effect of THP-1 cells on the formation of vessel-like structures by endothelial cells in the presence of placenta-conditioned media. Addition of THP-1 cells to endothelial cells cultured in the presence of media conditioned by first-trimester placentas led to an increase in the length of cell tubes and reduced their number in comparison with endothelial cell monoculture. In the presence of media conditioned by third-trimester placentas, THP-1 cells did not affect the length and number of cell tubes formed by endothelial cells...
February 27, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28239757/predictive-factor-of-secondary-tricuspid-regurgitation-after-aortic-valve-replacement-for-aortic-stenosis-the-importance-of-myocardial-hypertrophy-and-diastolic-dysfunction
#9
Takashi Igarashi, Masahiro Tanji, Koki Takahashi, Keiichi Ishida, Satomi Sasaki, Hitoshi Yokoyama
OBJECTIVES: The aim of this study is to determine the predictors of secondary tricuspid regurgitation after aortic valve replacement for aortic stenosis. METHODS: Seventy-one patients, who underwent aortic valve replacement for aortic stenosis at our institute from January 2006 to July 2011, were divided into two groups: an STR group, which included 15 patients with moderate or greater than moderate secondary tricuspid regurgitation at a follow-up visit and a control group...
February 26, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28239755/increasing-cancer-screening-among-old-order-anabaptist-women-through-specialized-women-s-health-and-integrated-cancer-screening-interventions
#10
Kate McBride, Dionne Gesink
Our objective was to develop, deliver, and evaluate a cancer screening intervention focused on rural Anabaptist communities in Ontario, Canada, to increase routine cancer screenings among women. We carried out three cancer prevention and screening interventions with Old Order Anabaptist women. Each intervention consisted of: transportation to the site, pre-arranged screening services, health teachings, fellowship and shopping, and an evaluative survey. Seventy five women total participated over three interventions...
February 27, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28239653/the-human-brain-produces-fructose-from-glucose
#11
Janice J Hwang, Lihong Jiang, Muhammad Hamza, Feng Dai, Renata Belfort-DeAguiar, Gary Cline, Douglas L Rothman, Graeme Mason, Robert S Sherwin
Fructose has been implicated in the pathogenesis of obesity and type 2 diabetes. In contrast to glucose, CNS delivery of fructose in rodents promotes feeding behavior. However, because circulating plasma fructose levels are exceedingly low, it remains unclear to what extent fructose crosses the blood-brain barrier to exert CNS effects. To determine whether fructose can be endogenously generated from glucose via the polyol pathway (glucose → sorbitol → fructose) in human brain, 8 healthy subjects (4 women/4 men; age, 28...
February 23, 2017: JCI Insight
https://www.readbyqxmd.com/read/28239652/estrogens-regulate-glycosylation-of-igg-in-women-and-men
#12
Altan Ercan, Wendy M Kohrt, Jing Cui, Kevin D Deane, Marija Pezer, Elaine W Yu, Jonathan S Hausmann, Harry Campbell, Ursula B Kaiser, Pauline M Rudd, Gordan Lauc, James F Wilson, Joel S Finkelstein, Peter A Nigrovic
The immunologic potency of IgG is modulated by glycosylation, but mechanisms regulating this process are undefined. A role for sex hormones is suggested by differences in IgG glycans between women and men, most prominently with respect to galactose. We therefore assessed IgG galactosylation in 713 healthy adults from 2 cohorts as well as in 159 subjects from 4 randomized controlled studies of endocrine manipulation: postmenopausal women receiving conjugated estrogens, raloxifene, or placebo; premenopausal women deprived of gonadal hormones with leuprolide and treated with estradiol or placebo; men deprived of gonadal hormones with goserelin and given testosterone or placebo; and men deprived of gonadal hormones with goserelin and given testosterone or placebo together with anastrozole to block conversion of testosterone to estradiol...
February 23, 2017: JCI Insight
https://www.readbyqxmd.com/read/28239632/dataset-on-growth-factor-levels-and-insulin-use-in-patients-with-diabetes-mellitus-and-incident-breast-cancer
#13
Zachary A P Wintrob, Jeffrey P Hammel, George K Nimako, Dan P Gaile, Alan Forrest, Alice C Ceacareanu
Growth factor profiles could be influenced by the utilization of exogenous insulin. The data presented shows the relationship between pre-existing use of injectable insulin in women diagnosed with breast cancer and type 2 diabetes mellitus, the growth factor profiles at the time of breast cancer diagnosis, and subsequent cancer outcomes. A Pearson correlation analysis evaluating the relationship between growth factors stratified by of insulin use and controls is also provided.
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28239631/early-adverse-life-events-are-associated-with-altered-brain-network-architecture-in-a-sex-dependent-manner
#14
Arpana Gupta, Emeran A Mayer, Jonathan R Acosta, Kareem Hamadani, Carinna Torgerson, John D van Horn, Lin Chang, Bruce Naliboff, Kirsten Tillisch, Jennifer S Labus
INTRODUCTION: Early adverse life events (EALs) increase the risk for chronic medical and psychiatric disorders by altering early neurodevelopment. The aim of this study was to examine associations between EALs and network properties of core brain regions in the emotion regulation and salience networks, and to test the influence of sex on these associations. METHODS: Resting-state functional and diffusion tensor magnetic resonance imaging were obtained in healthy individuals (61 men, 63 women)...
December 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28239604/predictors-of-antenatal-care-skilled-birth-attendance-and-postnatal-care-utilization-among-the-remote-and-poorest-rural-communities-of-zambia-a-multilevel-analysis
#15
Choolwe Jacobs, Mosa Moshabela, Sitali Maswenyeho, Nildah Lambo, Charles Michelo
OBJECTIVE: Optimal utilization of maternal health-care services is associated with reduction of mortality and morbidity for both mothers and their neonates. However, deficiencies and disparity in the use of key maternal health services within most developing countries still persist. We examined patterns and predictors associated with the utilization of specific indicators for maternal health services among mothers living in the poorest and remote district populations of Zambia. METHODS: A cross-sectional baseline household survey was conducted in May 2012...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28239590/socio-demographic-correlates-of-rhinosporidiosis-a-hospital-based-epidemiologic-study-in-purulia-india
#16
Sirshak Dutta, Dibakar Haldar, Mainak Dutta, Sabyasachi Barik, Kaustuv Das Biswas, Ramanuj Sinha
The present paper attempts to explore the socio-demographic profile of patients with rhinosporidiosis in an endemic area. A cross-sectional study was carried out in a tertiary-care hospital in Purulia district, India, including consecutive patients with histologically-proved rhinosporidiosis. Their socio-demographic profiles were obtained through a pre-designed proforma with given epidemiologic parameters. Data was statistically analyzed with inputs from literature review. Of the 39 patients included, 87 % were fresh/new cases...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239560/risk-factors-for-hearing-impairment-among-adults-with-diabetes-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#17
Kathleen E Bainbridge, Catherine C Cowie, Franklyn Gonzalez, Howard J Hoffman, Elizabeth Dinces, Jeremiah Stamler, Karen J Cruickshanks
AIM: The aim was to examine risk factors for hearing impairment among Hispanic/Latino adults with diabetes. METHODS: Findings are based on 3384 participants aged 18-76 years with diagnosed or previously undetected diabetes who completed audiometric testing as part of the Hispanic Community Health Study/Study of Latinos. We defined hearing impairment as the pure-tone average (PTA) >25 decibels hearing level [dB HL] of pure-tone thresholds at high frequencies (3000, 4000, 6000, and 8000 Hz) in the worse ear and defined a second hearing impairment outcome with the additional requirement of PTA >25 dB HL of low/mid-frequency (500, 1000, and 2000 Hz) thresholds in the worse ear...
December 2016: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/28239559/gene-profiling-the-window-of-implantation-microarray-analyses-from-human-and-rodent-models
#18
Jennifer L Herington, Yan Guo, Jeff Reese, Bibhash C Paria
Poor uterine receptivity leads to implantation defects or failure. Identification of uterine molecules crucial to uterine receptivity and/or embryo implantation provides the opportunity to design a diagnostic screening toolkit for uterine receptivity or targeted drug discovery for treating implantation-based infertility. In this regard, gene-profiling studies performed in humans and rodents have identified numerous genes involved in the transcriptional regulation of uterine receptivity and embryo implantation...
December 2016: J Reprod Health Med
https://www.readbyqxmd.com/read/28239530/hippocampal-atrophy-and-memory-dysfunction-associated-with-physical-inactivity-in-community-dwelling-elderly-subjects-the-sefuri-study
#19
Manabu Hashimoto, Yuko Araki, Yuki Takashima, Kohjiro Nogami, Akira Uchino, Takefumi Yuzuriha, Hiroshi Yao
BACKGROUND: Physical inactivity is one of the modifiable risk factors for hippocampal atrophy and Alzheimer's disease. We investigated the relationship between physical activity, hippocampal atrophy, and memory using structural equation modeling (SEM). MATERIALS AND METHODS: We examined 213 community-dwelling elderly subjects (99 men and 114 women with a mean age of 68.9 years) without dementia or clinically apparent depression. All participants underwent Mini-Mental State Examination (MMSE) and Rivermead Behavioral Memory Test (RBMT)...
February 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28239508/empirical-investigation-of-a-model-of-sexual-minority-specific-and-general-risk-factors-for-intimate-partner-violence-among-lesbian-women
#20
Robin J Lewis, Tyler B Mason, Barbara A Winstead, Michelle L Kelley
OBJECTIVE: This study proposed and tested the first conceptual model of sexual minority specific (discrimination, internalized homophobia) and more general risk factors (perpetrator and partner alcohol use, anger, relationship satisfaction) for intimate partner violence among partnered lesbian women. METHOD: Self-identified lesbian women (N=1048) were recruited from online market research panels. Participants completed an online survey that included measures of minority stress, anger, alcohol use and alcohol-related problems, relationship satisfaction, psychological aggression, and physical violence...
January 2017: Psychology of Violence
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