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https://www.readbyqxmd.com/read/29909600/patients-knowledge-about-the-outcomes-of-thyroid-biopsy-a-patient-survey
#1
Naykky Singh Ospina, Ana Castaneda-Guarderas, Russell Ward, Juan P Brito, Spyridoula Maraka, Claudia Zeballos Palacios, Kathleen J Yost, Diana S Dean, Victor M Montori
PURPOSE: Fine-needle aspiration biopsy of the thyroid is an increasingly common outpatient procedure. Patients are counseled about the indications and risks of this procedure and informed consent is obtained. We aimed to assess the extent to which patients acquired necessary knowledge during this process. METHODS: Survey study conducted in a thyroid nodule clinic at a referral center. Adult patients who had just undergone a thyroid biopsy were asked to complete a survey, including eight questions regarding the indications and potential outcomes of thyroid biopsy...
June 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29909595/disability-experiences-and-perspectives-regarding-reproductive-decisions-parenting-and-the-utility-of-genetic-services-a-qualitative-study
#2
C Roadhouse, C Shuman, K Anstey, K Sappleton, D Chitayat, E Ignagni
Genetic counselors adopt seemingly contradictory roles: advocating for individuals with genetic conditions while offering prenatal diagnosis and the option of selective termination to prevent the birth of a child with a disability. This duality contributes to the tension between the disability and clinical genetics communities. Varying opinions exist amongst the disability community: some value genetic services while others are opposed. However, there is limited research exploring the opinions of individuals with a disability regarding issues related to reproduction and genetic services in the context of personal experience...
June 16, 2018: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29909589/-it-was-not-my-aim-to-sleep-there-the-impact-of-timing-and-location-of-sex-on-adherence-to-coitally-dependent-hiv-pre-exposure-prophylaxis
#3
Fiona Scorgie, Jonathan Stadler, Deborah Baron, Susan Ju, Tshepiso Ikaneng, Zonke Mabude, Sylvia Makgopa, Matshidiso A Malefo, Kgahlisho N Manenzhe, Thulani Mazibuko, Hilda Ntjana, Busi Nkala, Thesla Palanee-Phillips, Glenda Gray, Helen Rees, Sinead Delany-Moretlwe
The FACTS 001 trial found that vaginal pre- and post-coital application of 1% tenofovir gel did not prevent HIV-1 infection amongst young South African women. The trial included a multi-faceted approach to adherence support and collected objective and self-reported adherence measures. Using qualitative data collected from a random sub-set of FACTS 001 participants (135 in-depth interviews at product discontinuation and 13 focus group discussions at dissemination of trial results), we explore the importance of 'place' and 'timing' in shaping acts of sexual intimacy and product adherence...
June 16, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29909577/population-pharmacokinetic-model-for-tumescent-lidocaine-in-women-undergoing-breast-cancer-surgery
#4
Camille Riff, Aurélie Bourgoin, Amelie Marsot, Laurent Allanioux, Marc Leone, Olivier Blin, Romain Guilhaumou
PURPOSE: Tumescent lidocaine anesthesia (TLA) is an opportunity to perform mastectomy for breast cancer without general anesthesia in elderly women. Few reports are available on the pharmacokinetics of lidocaine in a context of TLA during a unilateral mastectomy. The aim of this study was to describe lidocaine pharmacokinetics in elderly women undergoing breast cancer surgery after TLA and to explore the risk of the toxicity of this technique. METHODS: A prospective study was conducted to examine the pharmacokinetics of lidocaine in women undergoing TLA...
June 16, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29909564/organized-screening-detects-breast-cancer-at-earlier-stage-regardless-of-molecular-phenotype
#5
Claire M B Holloway, Li Jiang, Marlo Whitehead, Jennifer M Racz, Patti A Groome
PURPOSE: Mortality reduction attributable to organized breast screening is modest. Screening may be less effective at detecting more aggressive cancers at an earlier stage. This study was conducted to determine the relative efficacy of screening mammography to detect cancers at an earlier stage by molecular phenotype. METHODS: We identified 2882 women with primary invasive breast cancer diagnosed between January 1, 2008 and December 31, 2012 and who had a mammogram through the Ontario Breast Screening Program in the 28 months before diagnosis...
June 16, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29909557/defining-normal-apical-vaginal-support-a-relook-at-the-posst-study
#6
Radhika Patnam, Autumn Edenfield, Steven Swift
INTRODUCTION AND HYPOTHESIS: The purpose of this study is to reanalyze data from the original 2005 Pelvic Organ Support Study (POSST) data set to define normal values for apical Pelvic Organ Prolapse Quantification (POP-Q) points C and D and total vaginal length (TVL) in an asymptomatic population of women. METHODS: In this retrospective observational data-set review, patient were >18 years presenting for annual gynecologic exams to six centers in the United States...
June 16, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29909556/the-urinary-microbiome-in-women-with-mixed-urinary-incontinence-compared-to-similarly-aged-controls
#7
Yuko M Komesu, Holly E Richter, Benjamin Carper, Darrell L Dinwiddie, Emily S Lukacz, Nazema Y Siddiqui, Vivian W Sung, Halina M Zyczynski, Beri Ridgeway, Rebecca G Rogers, Lily A Arya, Donna Mazloomdoost, Marie G Gantz
INTRODUCTION & HYPOTHESIS: Previous studies have suggested that women with urinary incontinence have an altered urinary microbiome. We hypothesized that the microbiome in women with mixed urinary incontinence (MUI) differed from controls and tested this hypothesis using bacterial gene sequencing techniques. METHODS: This multicenter study compared the urinary microbiome in women with MUI and similarly aged controls. Catheterized urine samples were obtained; v4-6 regions of the 16S rRNA gene were sequenced to identify bacteria...
June 16, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29909555/effects-of-mesh-related-complications-in-vaginal-surgery-on-quality-of-life
#8
Claudia R Kowalik, Mariëlle M E Lakeman, Alyde T de Kraker, Jan Paul W R Roovers
INTRODUCTION AND HYPOTHESIS: Vaginal mesh surgery is subject of debate due to the impact of mesh-related complications on patient's lives. Not all of these complications are symptomatic. Restoration of the anatomy and improvement of pelvic floor function as a result may counter the experienced discomfort related to adverse events. We hypothesized that health-related quality of life (HR-QoL) is comparable in women after vaginal mesh surgery regardless of the presence or absence of a mesh-specific complication...
June 16, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29909515/influence-of-biliopancreatic-diversion-on-pregnancy-outcomes-in-comparison-to-other-bariatric-surgery-procedures
#9
S De Carolis, A Botta, Gelsomina Del Sordo, R Guerrisi, S Salvi, M P De Carolis, A Iaconelli, P Giustacchini, M Raffaelli, A Lanzone
BACKGROUND: Pregnancy after bariatric surgery (BS) has an increased risk for small-for-gestational-age infants (SGA), shorter length of gestation, and probably perinatal mortality. The aim of this study was to investigate if biliopancreatic diversion could impair pregnancy outcomes in comparison to other bariatric surgery procedures. METHODS: We conducted a cohort retrospective single-center study in 65 women before and after BS. Thirty-one pregnancies occurred before BS, while 109 after BS, amongst which n = 51 after biliopancreatic diversion (BPD) and n = 58 after non-malabsorptive procedures...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909508/associations-of-mental-health-and-sleep-duration-with-menstrual-cycle-irregularity-a-population-based-study
#10
Taeryoon Kim, Ga Eun Nam, Byoungduck Han, Sung Jung Cho, Junghun Kim, Do Hyun Eum, Sang Woo Lee, Soon Hong Min, Woohyun Lee, Kyungdo Han, Yong Gyu Park
This study aimed to examine whether the characteristics of mental health and sleep duration, alone or in combination, are associated with menstrual cycle irregularity. This population-based, cross-sectional study analyzed the data from 4445 women aged 19-49 years, who participated in the Korea National Health and Nutrition Examination Survey 2010-2012. A structured questionnaire was used to assess mental health characteristics, sleep duration, and menstrual cycle irregularity. A multivariable logistic regression analysis was performed...
June 16, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29909490/heavy-metals-in-indigenous-preparations-used-for-sex-selection-during-pregnancy-in-india
#11
Abhijit Ganguli, Pragya Rai, Sarala Balachandran, Rakesh Gupta, Rashmi Sharma, Sutapa Bandyopadhyay Neogi
Indigenous preparations (IPs) have evoked a considerable interest in alleviating infections and chronic diseases and improving wellbeing. While such formulations have been a part of traditional practice in several countries and many have been reviewed scientifically for their claims, several of them until date remain to be investigated. A class of IPs for sex selection by Indian pregnant women exists with an aim of begetting a male offspring. In view of the leads obtained from our previous studies on detrimental effects of the newborn, for instance stillbirths and congenital malformations, we attempted to investigate the samples for heavy metal toxicity...
June 16, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29909484/fatigue-in-the-general-population-german-normative-values-of-the-eortc-qlq-fa12
#12
Andreas Hinz, Joachim Weis, Elmar Brähler, Anja Mehnert
PURPOSE: Fatigue is a frequent symptom in patients suffering from chronic diseases, especially cancer patients. A new fatigue questionnaire was recently developed to better assess this condition, the EORTC QLQ-FA12. The aims of this study were to test the psychometric properties of this fatigue questionnaire and to provide normative values. METHODS: A total of 2411 individuals (53.5% women), representatively selected from the German general population, responded to the EORTC QLQ-FA12 questionnaire...
June 16, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29909471/pet-ct-and-prediction-of-thyroid-cancer-in-patients-with-follicular-neoplasm-or-atypia
#13
Thao T Nguyen, Natascha G E Lange, Anne L Nielsen, Anders Thomassen, Helle Døssing, Christian Godballe, Max Rohde
PURPOSE: To examine whether addition of 18 F-fluoro-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) to fine needle aspiration biopsy (FNAB) would improve prediction of thyroid cancer in patients with FNAB-derived follicular neoplasm or atypia, classified according to focal, multifocal, diffuse, or no FDG uptake. MATERIALS AND METHODS: Consecutive patients with FNAB-derived follicular neoplasm or atypia planned for surgery from September 2013 to March 2016 were prospectively included and considered for analysis...
June 16, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29909444/gender-disparities-in-presentation-management-and-outcomes-of-acute-myocardial-infarction
#14
REVIEW
Matthew Liakos, Puja B Parikh
PURPOSE OF REVIEW: This review provides updates in gender disparities in the symptom profile, risk factors, quality and timeliness of guideline-based medical care, and clinical outcomes, including mortality, bleeding, and vascular complications, in patients with acute myocardial infarction (AMI). RECENT FINDINGS: While AMI continues to be a leading cause of mortality in both men and women, significant gender differences exist in presentation, management, and outcomes...
June 16, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29909404/aortic-arch-width-and-cardiovascular-disease-in-men-and-women-in-the-community
#15
Michael L Chuang, Philimon N Gona, Saadia Qazi, Rebecca M Musgrave, Caroline S Fox, Joseph M Massaro, Udo Hoffmann, Christopher J O'Donnell
BACKGROUND: We sought to determine whether increased aortic arch width (AAW) adds to standard Framingham risk factors and coronary artery calcium (CAC) for prediction of incident adverse cardiovascular disease (CVD) events in community-dwelling adults. METHODS AND RESULTS: A total of 3026 Framingham Heart Study Offspring and Third Generation cohort participants underwent noncontrast multidetector computed tomography from 2002 to 2005 to quantify CAC. We measured AAW as the distance between the centroids of the ascending and descending thoracic aorta, at the level of main pulmonary artery bifurcation or the right pulmonary artery...
June 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29909401/prevalence-and-long-term-survival-after-coronary-artery-bypass-grafting-in-women-and-men-with-heart-failure-and-preserved-versus-reduced-ejection-fraction
#16
Louise Y Sun, Jack V Tu, Anan Bader Eddeen, Peter P Liu
BACKGROUND: Heart failure (HF) with reduced ejection fraction (rEF) is a widely regarded prognosticator after coronary artery bypass grafting. HF with preserved ejection fraction (pEF) accounts for up to half of all HF cases and is associated with considerable morbidity and mortality in hospitalized cohorts. However, HFpEF outcomes have not been elucidated in cardiac surgical patients. We investigated the prevalence and outcomes of HFpEF and HFrEF in women and men following coronary artery bypass grafting...
June 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29909377/effect-of-aspirin-on-cancer-chemoprevention-in-japanese-patients-with-type-2-diabetes-10-year-observational-follow-up-of-a-randomized-controlled-trial
#17
Sadanori Okada, Takeshi Morimoto, Hisao Ogawa, Mio Sakuma, Chisa Matsumoto, Hirofumi Soejima, Masafumi Nakayama, Naofumi Doi, Hideaki Jinnouchi, Masako Waki, Izuru Masuda, Yoshihiko Saito
OBJECTIVE: This study analyzed the efficacy of low-dose aspirin in cancer chemoprevention in patients with diabetes. RESEARCH DESIGN AND METHODS: This study was a posttrial follow-up of the Japanese Primary Prevention of Atherosclerosis with Aspirin for Diabetes (JPAD) trial. Participants in the JPAD trial (2,536 Japanese patients with type 2 diabetes and without preexisting cardiovascular disease) were randomly allocated to receive aspirin (81 or 100 mg daily) or no aspirin...
June 16, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29909297/results-of-surgical-treatment-of-de-quervain-s-tenosynovitis-80-cases-with-a-mean-follow-up-of-9-5-years
#18
Johanne J Garçon, Bertille Charruau, Emilie Marteau, Jacky Laulan, Guillaume Bacle
INTRODUCTION: Surgery is indicated in De Quervain's tenosynovitis only after failure of medical treatment, often due to individual anatomical variants. We use Le Viet's technique, to avoid tendon instability. The aim of the present study was to evaluate long-term results, with the hypothesis that this surgical technique is reliable, providing lasting results. PATIENTS AND METHODS: All patients operated on between 1993 and 2015 were included, and results were assessed by telephone questionnaire at a minimum 1 year's follow-up...
June 14, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29909296/anterior-cruciate-ligament-reconstruction-with-the-tape-locking-screw-tls-and-a-short-hamstring-graft-clinical-evaluation-of-61-cases-with-a-minimum-12-months-follow-up
#19
Benoît Orfeuvre, Régis Pailhé, Loïc Sigwalt, Brice Rubens Duval, Gabriel Lateur, Stéphane Plaweski, Dominique Saragaglia
INTRODUCTION: The TLS® technique for anterior cruciate ligament (ACL) reconstruction has the advantages of using only one hamstring tendon (semitendinosus) by preparing a short graft secured with screws and braided strips. The theoretical pitfall of this technique is that the graft length is determined arbitrarily. Thus, if the blind tunnels are not long enough, it will be impossible to tension the graft properly upon fixation. The primary objective of this study was to determine the postoperative side-to-side difference in knee laxity...
June 14, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29909293/learning-to-actively-cope-with-stress-in-female-mice
#20
David M Lyons, Christine L Buckmaster, Alan F Schatzberg
Repeated exposure to a same-sex resident stranger enhances subsequent indications of active coping that generalize across multiple contexts in intruder male mice. Here we investigate female mice for comparable learning to cope training effects. Stress coping research focused on females is important because stress related mood and anxiety disorders are more prevalent in women than men. Female mice were monitored for coping behavior in open-field, object-exploration, and tail-suspension tests conducted after repeated exposure to a same-sex resident stranger...
June 9, 2018: Psychoneuroendocrinology
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