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dissociative fugue

Ajith Kumar A, Siva Kumar Nadimpalli
Mannose 6-phosphate/IGF-II receptor mediated lysosomal clearance of insulin-like growth factor-II is significantly associated with the evolution of placental mammals. The protein is also referred to as the IGF-II receptor. Earlier studies suggested relatively low binding affinity between the receptor and ligand in prototherian and metatherian mammals. In the present study, we cloned the IGF-II binding domain of the early vertebrate fugu fish and expressed it in bacteria. A 72000Da truncated receptor containing the IGF-II binding domain was obtained...
July 1, 2018: International Journal of Biological Macromolecules
Angelica Staniloiu, Hans J Markowitsch, Andreas Kordon
Autobiographical amnesia is found in patients with focal or diffuse brain damage ("organic amnesia"), but also without overt brain damage (at least when measured with conventional brain imaging methods). This last condition is usually named dissociative amnesia at present, and was originally described as hysteria. Classically and traditionally, dissociative amnesia is seen as a disorder that causes retrograde amnesia in the autobiographical domain in the aftermath of incidents of major psychological stress or trauma...
February 2018: Neuropsychologia
Neil A Harrison, Kate Johnston, Federica Corno, Sarah J Casey, Kimberley Friedner, Kate Humphreys, Eli J Jaldow, Mervi Pitkanen, Michael D Kopelman
There are very few case series of patients with acute psychogenic memory loss (also known as dissociative/functional amnesia), and still fewer studies of outcome, or comparisons with neurological memory-disordered patients. Consequently, the literature on psychogenic amnesia is somewhat fragmented and offers little prognostic value for individual patients. In the present study, we reviewed the case records and neuropsychological findings in 53 psychogenic amnesia cases (ratio of 3:1, males:females), in comparison with 21 consecutively recruited neurological memory-disordered patients and 14 healthy control subjects...
September 1, 2017: Brain: a Journal of Neurology
Doval Nimisha, Batra Dhruv, Moun Vikas, Jha K Sneh, Shukla Rakesh
Therapeutic outcome of Wilson's disease significantly depends upon its early recognition. As Wilson's disease is a rare disorder with protean manifestations, its diagnosis and subsequent treatment are often delayed. We elaborate here the case of a young boy who had initially presented with psychiatrc symptoms suggestive of dissociative fugue followed by withdrawn behaviour and was treated by a psychiatrist with minimal response. This was associated with symptoms of tremors, hypersalivation, and slowness of movements...
July 2016: Indian Journal of Psychological Medicine
Hareesh Angothu, Lokeswar Reddy Pabbathi
Dissociative fugue is rare entity to encounter with possible differentials of epilepsy and malingering. It is one of the dissociative disorders rarely seen in clinical practice more often because of the short lasting nature of this condition. This might also be because of organized travel of the individuals during the episodes and return to their families after the recovery from episodes. This is a case description of a patient who has experienced total three episodes of dissociative fugue. The patient has presented during the third episode and two prior episodes were diagnosed as fugue episodes retrospectively based on the history...
March 2016: Indian Journal of Psychological Medicine
Pravesh Sharma, Medhat Guirguis, Jessica Nelson, Terry McMahon
No abstract text is available yet for this article.
2015: Primary Care Companion to CNS Disorders
Kenichiro Okano
This paper discusses the way informed psychiatrists are expected to handle dissociative patients in clinical situations, with a specific focus on dissociative identity disorders and dissociative fugue. On the initial interview with dissociative patients, information on their history of trauma and any nascent dissociative symptoms in their childhood should be carefully obtained. Their level of stress in their current life should also be assessed in order to understand their symptomatology, as well as to predict their future clinical course...
2015: Seishin Shinkeigaku Zasshi, Psychiatria et Neurologia Japonica
Dushad Ram, H G Ashoka, Basavnna Gowdappa
Inadequate glycemic control in patients with diabetes is known to be associated with psychiatric disorders such as depression, anxiety disorder, and cognitive impairment. However, dissociative syndrome has not been reported so far. Here we are reporting a case of repeated dissociative fugue associated with hyperglycemia, in an elderly with type II diabetes. Possible neurobiological mechanism has been discussed.
July 2015: Journal of Family Medicine and Primary Care
Chintan Madhusudan Raval, Sunnetkumar Upadhyaya, Bharat Navinchandra Panchal
Dissociative fugue is a rare disorder which has been described as sudden, unexpected, travel away from home or one's customary place of daily activities, with the inability to recall some or all of one's past. There is no systematic data existing on it and very few cases reported in the literature. Here we report a case of fugue in a young adult male who travelled 8 times away from his home during last 1½ year. He has a loss of memory for episodes with patchy recall of few events. Longest duration of fugue episode was of 1-month...
January 2015: Industrial Psychiatry Journal
Dorothy Liu-Barbaro, Murray Stein
Despite widespread awareness of their frequent co-occurrence, little is known about treatment of individuals with comorbid posttraumatic stress disorder (PTSD) and dissociative disorders. Patients with dissociative disorders do not respond well to standard exposure therapy, and few psychopharmacologic trials exist. Fluoxetine proved ineffective for depersonalization disorder, but paroxetine showed efficacy in decreasing dissociative symptoms in PTSD patients.
July 2015: Journal of Clinical Psychiatry
Vedat Şar
It has been claimed that the progress of psychiatry has lagged behind that of other medical disciplines over the last few decades. This may suggest the need for innovative thinking and research in psychiatry, which should consider neglected areas as topics of interest in light of the potential progress which might be made in this regard. This review is concerned with one such field of psychiatry: dissociation and dissociative disorders. Dissociation is the ultimate form of human response to chronic developmental stress, because patients with dissociative disorders report the highest frequency of childhood abuse and/or neglect among all psychiatric disorders...
December 2014: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
J Montant, M Adida, R Belzeaux, M Cermolacce, D Pringuey, D Da Fonseca, J-M Azorin
The phenomenology of dissociative disorders may be complex and sometimes confusing. We describe here two cases who were initially misdiagnosed. The first case concerned a 61 year-old woman, who was initially diagnosed as an isolated dissociative fugue and was actually suffering from severe major depressive episode. The second case concerned a 55 year-old man, who was suffering from type I bipolar disorder and polyvascular disease, and was initially diagnosed as dissociative fugue in a mooddestabilization context, while it was finally a stroke...
December 2014: L'Encéphale
Edward Helmes, Julie-May Brown, Linda Elliott
Dissociative fugue refers to loss of personal identity, often with the associated loss of memories of events (general amnesia). Here we report on the psychological assessment of a 54-year-old woman with loss of identity and memories of 33 years of her life attributed to dissociative fugue, along with a follow-up 11 years later. Significant levels of personal injury and stress preceded the onset of the amnesia. A detailed neuropsychological assessment was completed at a university psychology clinic, with a follow-up assessment there about 11 years later with an intent to determine whether changes in her cognitive status were associated with better recall of her life and with her emotional state...
2015: Journal of Trauma & Dissociation
Julie P Gentile, Malynda Snyder, Paulette Marie Gillig
Depersonalization/derealization disorder is characterized by depersonalization often co-occurring with derealization in the absence of significant psychosis, memory, or identity disturbance. Depersonalization/derealization is categorized as one of the dissociative disorders, which also includes dissociative amnesia, dissociative fugue, dissociative identity disorder, and forms of dissociative disorder not otherwise specified. Although these disorders may be under-diagnosed or misdiagnosed, many persons with psychiatric illness who have experienced trauma report symptoms consistent with dissociative disorders...
July 2014: Innovations in Clinical Neuroscience
C Thomas-Antérion, F Dubas, M Decousus, C Jeanguillaume, E Guedj
BACKGROUND: Precipitated by psychological stress, dissociative amnesia occurs in the absence of identifiable brain damage. Its clinical characteristics and functional neural basis are still a matter of controversy. METHODS: In the present paper, we report 3 cases of retrograde autobiographical amnesia, characterized by an acute onset concomitant with emotional/neurological precipitants. We present 2 cases of dissociative amnesia with fugue (cases 1 and 2), and one case of focal dissociative amnesia after a minor head trauma (case 3)...
October 2014: Neurophysiologie Clinique, Clinical Neurophysiology
Y U Sekine
The subject of this report murdered four young girls between 1988 and 1989. The forensic psychiatric evaluation showed that soon after the sudden death of his dearest grandfather he had developed dissociative symptoms including depersonalization, autoscopy, fugue, dissociative amnesia, Ganser's syndrome and DID, on the basis of earlier traumatic experiences under the dysfunctional family circumstances of his early childhood. His DID was thought to be manifest in at least four personalities, i.e., a host personality, a child personality, a cool personality and a female personality...
2000: International Journal of Psychiatry in Clinical Practice
Abhishek Mamarde, Praveen Navkhare, Amrita Singam, Akash Kanoje
Dissociative fugue is a rarely reported diagnostic entity. It is one of the least understood and yet clinically one of the most fascinating disorders in mental health. Here, we describe a case of fugue in a 32-year-old man who was brought to mental hospital with complete loss of memory for events pertaining to identity of self. This case illustrates the nature of presentation in hospital setting like mental hospital and effort taken to reintegrate his identity and reunite with his family.
October 2013: Indian Journal of Psychological Medicine
Inna Roberts, Natalie Gluck, Michael S Smith, Mary F Morrison
No abstract text is available yet for this article.
December 2013: American Journal of Psychiatry
Monday N Igwe
INTRODUCTION: Dissociative fugue is a psychiatric disorder characterized by amnesia coupled with sudden unexpected travel away from the individual's usual surroundings and denial of all memory of his or her whereabouts during the period of wandering. Dissociative fugue is a rare disorder that is infrequently reported. Before now, no case of it had been reported in a medical student. CASE PRESENTATION: This article focuses on the report of a case of dissociative fugue symptoms in a 28-year-old male Nigerian medical student...
May 31, 2013: Journal of Medical Case Reports
Julie P Gentile, Kristy S Dillon, Paulette Marie Gillig
There is a wide variety of what have been called "dissociative disorders," including dissociative amnesia, dissociative fugue, depersonalization disorder, dissociative identity disorder, and forms of dissociative disorder not otherwise specified. Some of these diagnoses, particularly dissociative identity disorder, are controversial and have been questioned by many clinicians over the years. The disorders may be under-diagnosed or misdiagnosed, but many persons who have experienced trauma report "dissociative" symptoms...
February 2013: Innovations in Clinical Neuroscience
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