keyword
MENU ▼
Read by QxMD icon Read
search

Intern

keyword
https://www.readbyqxmd.com/read/28641403/a-molasses-habitat-derived-fungus-aspergillus-tubingensis-xg21-with-high-%C3%AE-fructofuranosidase-activity-and-its-potential-use-for-fructooligosaccharides-production
#1
Yijia Xie, Huanxia Zhou, Caixia Liu, Jing Zhang, Ning Li, Zhanli Zhao, Guoyong Sun, Yaohua Zhong
The industrial microorganisms used for fructooligosaccharides (FOS) synthesis are generally fermented with sucrose as carbon source to induce the production of β-fructofuranosidase (FFase) having transfructosylation activity. Consequently, isolation of novel FFase producers from a sucrose-enriched biotope would help improve FOS productivity and reduce the process cost. Here, three fungi isolated from a unique sugarcane molasses habitat were found to possess FFase activity and one of them, XG21, exhibited a high capacity to synthesize FOS...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28641362/estimating-the-potential-cost-of-a-high-dose-immune-tolerance-induction-iti-therapy-relative-to-the-cost-of-a-combined-therapy-of-a-low-dose-iti-therapy-with-bypassing-agent-prophylaxis
#2
G Kenet, A Oladapo, J D Epstein, C Thompson, A Novack, D J Nugent
INTRODUCTION: The International Immune Tolerance Study (I-ITI) demonstrated comparable success rates between low (FVIII 50 IU/kg/TIW) and high dose (FVIII 200 IU/kg/day) regimens. While costlier, the high dose ITI regimen achieved shorter time-to-treatment success with fewer bleeding episodes compared to the low dose ITI regimen. Adding bypassing agent prophylaxis (BAP) to a low dose ITI regimen may reduce bleeding while still being less costly than high dose ITI. AIM AND METHODS: An economic model was developed to compare high dose ITI to low dose ITI with BAP...
June 22, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28641358/-pain-treatment-after-thoracic-surgery
#3
Holger Hendrix, Vladimir Kamlak, Georgi Prisadov, Katrin Welcker
The treatment of pain after thoracic surgery is a challenge and takes place in the individual clinics mostly according to clinic internal standards. It exists no currently valid S3 guideline for the treatment of acute perioperative and posttraumatic pain. For an effective pain treatment as well individual pain experience as the pain intensity of the various thoracic surgical procedures must be considered. Regular pain assessment with appropriate methods and their documentation form the basis for adequate and adapted pain therapy...
June 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/28641302/7-hexagon-multifocal-electroretinography-for-an-objective-functional-assessment-of-the-macula-in-14-seconds
#4
Etienne M Schönbach, Voraporn Chaikitmongkol, Rachel Annam, Emma C McDonnell, Yulia Wolfson, Emily Fletcher, Hendrik P N Scholl
PURPOSE: We present the multifocal electroretinogram (mfERG) with a 7-hexagon array as an objective test of macular function that can be recorded in 14 s. We provide normal values and investigate its reproducibility and validity. METHODS: Healthy participants underwent mfERG testing according to International Society for Clinical Electrophysiology of Vision (ISCEV) standards using the Espion Profile/D310 multifocal ERG system (Diagnosys, LLC, Lowell, MA, USA). One standard recording of a 61-hexagon array and 2 repeated recordings of a custom 7-hexagon array were obtained...
June 23, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28641241/influence-of-shoulder-kinematic-estimate-on-joint-and-muscle-mechanics-predicted-by-musculoskeletal-model
#5
Yoann Blache, Mickael Begon
Little information is available in the existing literature regarding the influence of the scapular kinematic estimate method on musculoskeletal analysis. This study aimed to assess the propagation of errors due to the method used for scapular kinematics reconstruction in the workflow of musculoskeletal modeling (joint kinematics, joint torques, muscle force and joint reaction force) in shoulder and upper-limb movements. Two participants performed functional (arm elevation and rotation), daily life (eating and reaching pants pockets) and sports movements (a simulated throwing maneuver)...
June 15, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28641201/pelvic-and-hip-kinematics-during-single-leg-drop-landing-are-altered-in-sports-participants-with-long-standing-groin-pain-a-cross-sectional-study
#6
L Janse van Rensburg, M Dare, Q Louw, L Crous, J Cockroft, L Williams, B Olivier
OBJECTIVES: The aim of this study was to determine the differences in three-dimensional pelvic and hip kinematics during a single-leg drop-landing task in active sports participants with long-standing groin pain compared to healthy matched controls. DESIGN: This was a descriptive study incorporating a cross-sectional design. SETTING: The study was conducted at the Unit for Human Movement Analysis, Stellenbosch University, South Africa. PARTICIPANTS: The study sample was comprised of 20 male club level soccer, rugby, running and cycling participants between the ages of 18 and 55 years...
May 12, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28641195/biotransformation-in-the-zebrafish-embryo-temporal-gene-transcription-changes-of-cytochrome-p450-enzymes-and-internal-exposure-dynamics-of-the-ahr-binding-xenobiotic-benz-a-anthracene
#7
Agnes Kühnert, Carolina Vogs, Bettina Seiwert, Silke Aulhorn, Rolf Altenburger, Henner Hollert, Eberhard Küster, Wibke Busch
Not much is known about the biotransformation capability of zebrafish (Danio rerio) embryos. For understanding possible toxicity differences to adult fish, it might be crucial to understand the biotransformation of chemicals in zebrafish embryos i.e. as part of toxicokinetics. The biotransformation capabilities were analysed for two different stages of zebrafish embryos in conjunction with the internal concentrations of a xenobiotic. Zebrafish embryos of the late cleavage/early blastula period (2-26 hpf) and the early pharyngula period (26-50 hpf) were exposed for 24 h to the AhR binding compound benz[a]anthracene (BaA)...
June 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28641131/children-s-brain-activation-during-risky-decision-making-a-contributor-to-substance-problems
#8
Thomas J Crowley, Manish S Dalwani, Joseph T Sakai, Kristen M Raymond, Shannon K McWilliams, Marie T Banich, Susan K Mikulich-Gilbertson
OBJECTIVE: Among young children excessive externalizing behaviors often predict adolescent conduct and substance use disorders. Adolescents with those disorders show aberrant brain function when choosing between risky or cautious options. We therefore asked whether similarly aberrant brain function during risky decision-making accompanies excessive externalizing behaviors among children, hypothesizing an association between externalizing severity and regional intensity of brain activation during risky decision-making...
June 4, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28641109/rare-copy-number-variants-in-nrxn1-and-cntn6-increase-risk-for-tourette-syndrome
#9
Alden Y Huang, Dongmei Yu, Lea K Davis, Jae Hoon Sul, Fotis Tsetsos, Vasily Ramensky, Ivette Zelaya, Eliana Marisa Ramos, Lisa Osiecki, Jason A Chen, Lauren M McGrath, Cornelia Illmann, Paul Sandor, Cathy L Barr, Marco Grados, Harvey S Singer, Markus M Nöthen, Johannes Hebebrand, Robert A King, Yves Dion, Guy Rouleau, Cathy L Budman, Christel Depienne, Yulia Worbe, Andreas Hartmann, Kirsten R Müller-Vahl, Manfred Stuhrmann, Harald Aschauer, Mara Stamenkovic, Monika Schloegelhofer, Anastasios Konstantinidis, Gholson J Lyon, William M McMahon, Csaba Barta, Zsanett Tarnok, Peter Nagy, James R Batterson, Renata Rizzo, Danielle C Cath, Tomasz Wolanczyk, Cheston Berlin, Irene A Malaty, Michael S Okun, Douglas W Woods, Elliott Rees, Carlos N Pato, Michele T Pato, James A Knowles, Danielle Posthuma, David L Pauls, Nancy J Cox, Benjamin M Neale, Nelson B Freimer, Peristera Paschou, Carol A Mathews, Jeremiah M Scharf, Giovanni Coppola
Tourette syndrome (TS) is a model neuropsychiatric disorder thought to arise from abnormal development and/or maintenance of cortico-striato-thalamo-cortical circuits. TS is highly heritable, but its underlying genetic causes are still elusive, and no genome-wide significant loci have been discovered to date. We analyzed a European ancestry sample of 2,434 TS cases and 4,093 ancestry-matched controls for rare (< 1% frequency) copy-number variants (CNVs) using SNP microarray data. We observed an enrichment of global CNV burden that was prominent for large (> 1 Mb), singleton events (OR = 2...
June 21, 2017: Neuron
https://www.readbyqxmd.com/read/28641091/increasing-rates-of-clostridium-difficile-infection-in-mexican-hospitals
#10
Laura Palau Dávila, Elvira Garza-González, Patricia Rodríguez-Zulueta, Rayo Morfín-Otero, Eduardo Rodríguez-Noriega, Diana Villar-Compte, Juan C Rodríguez-Aldama, Adrián Camacho-Ortiz
INTRODUCTION: The epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world. METHODS: This was a retrospective and observational study from four hospitals of three Mexican cities. Patients were diagnosed with CDI when presented with loose stools and had at least one of the following tests positive: toxins assay, real-time PCR, or an endoscopic image compatible with pseudomembranous colitis...
June 19, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28641088/application-of-zeolite-hydrous-zirconia-composite-as-a-novel-sediment-capping-material-to-immobilize-phosphorus
#11
Yi Fan, Yiwen Li, Deyi Wu, Chunjie Li, Hainan Kong
A unique sediment-capping agent consisting of a zeolite/hydrous zirconia composite (ZHZ) was developed and tested for P-immobilization in the overlying water and sediment cores from a freshwater pond. In the ZHZ, NaP1 zeolite was covered with hydrous zirconia, which existed as an amorphous phase. Experimental results in pond water indicated that ZHZ could efficiently remove soluble reactive phosphorus. The 28-day sediment incubation experiments showed that capping sediment with ZHZ resulted in a more efficient, rapid and sustained decrease in P concentration when compared with the traditional alum treatment method...
June 12, 2017: Water Research
https://www.readbyqxmd.com/read/28641063/launching-adoptees-into-adulthood-mothers-and-fathers-promotion-of-volitional-functioning
#12
Sonia Ranieri, Laura Ferrari, Daniela Barni, Rosa Rosnati
In the psychological literature, there is growing evidence that parental support of children's volitional functioning is one of the most prominent protective factors during adolescence and the transition to adulthood. According to the Self-Determination Theory, children cope best with developmental tasks when they acquire a sense of self-governance and self-endorsed functioning. In the field of adoption research, however, the parental promotion of volitional functioning (PVF) and its relation to the adopted child's development are still underinvestigated...
July 2017: Journal of Prevention & Intervention in the Community
https://www.readbyqxmd.com/read/28641034/imaging-of-proximal-lacrimal-system-with-time-domain-anterior-segment-optical-coherence-tomography-in-asian-indian-population
#13
Swati Singh, Arnav Ghosh, Suryasnata Rath
This article reports proximal lacrimal system parameters using Anterior Segment Optical Coherence Tomography (ASOCT-Visante) in an apparently normal Asian Indian population with assessment of any correlation between tear meniscus height and punctal diameter. This was a prospectively designed observational study that included healthy adults, who volunteered for optical coherence tomography imaging (OCT) of their proximal lacrimal system. Time domain ASOCT (Visante) images of the punctum and proximal canaliculus were captured using the high resolution corneal scan protocol...
June 22, 2017: Orbit
https://www.readbyqxmd.com/read/28640995/colloidal-gold-nanoparticles-induce-changes-in-cellular-and-subcellular-morphology
#14
Xiaowei Ma, Raimo Hartmann, Dorleta Jimenez de Aberasturi, Fang Yang, Stefaan J H Soenen, Bella B Manshian, Jonas Franz, Daniel Valdeperez, Beatriz Pelaz, Neus Feliu, Norbert Hampp, Christoph Riethmüller, Henning Vieker, Natalie Frese, Armin Gölzhäuser, Michael Simonich, Robert L Tanguay, Xing-Jie Liang, Wolfgang J Parak
Exposure of cells to colloidal nanoparticles (NPs) can have concentration-dependent harmful effects. Mostly, such effects are monitored with biochemical assays or probes from molecular biology, i.e. viability assays, gene expression profiles, etc., neglecting that the presence of NPs can also drastically affect cellular morphology. In the case of polymer-coated Au NPs we demonstrate that upon NP internalization, cells undergo lysosomal swelling, alterations in mitochondrial morphology, disturbances in actin and tubulin cytoskeleton and associated signaling, and reduction of focal adhesion contact area and number of filopodia...
June 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28640977/neurogenic-bowel-dysfunction-clinical-management-recommendations-of-the-neurologic-incontinence-committee-of-the-fifth-international-consultation-on-incontinence-2013
#15
REVIEW
Nikki Cotterill, Helmut Madersbacher, Jean J Wyndaele, Apostolos Apostolidis, Marcus J Drake, Jerzy Gajewski, John Heesakkers, Jalesh Panicker, Piotr Radziszewski, Ryuji Sakakibara, Karl-Dietrich Sievert, Rizwan Hamid, Thomas M Kessler, Anton Emmanuel
BACKGROUND: Evidence-based guidelines for the management of neurological disease and lower bowel dysfunction have been produced by the International Consultations on Incontinence (ICI). These are comprehensive guidelines, and were developed to have world-wide relevance. AIMS: To update clinical management of neurogenic bowel dysfunction from the recommendations of the 4th ICI, 2009. MATERIALS AND METHODS: A series of evidence reviews and updates were performed by members of the working group...
June 22, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28640958/recommendations-for-revision-of-chinese-diagnostic-criterion-for-metabolic-syndrome-a-nationwide-study
#16
Ying Xing, Shaoyong Xu, Aihua Jia, Jing Cai, Mingwei Zhao, Jianhua Guo, Qiuhe Ji, Jie Ming
BACKGROUND: The metabolic syndrome (MS) criterion proposed by Chinese Diabetes Society (CDS) may have limitations, because it requires an additional 2-hour postprandial plasma glucose (2 h-PPG) to diagnose hyperglycemia. We aimed to revise the CDS criterion by removing the 2 h-PPG test, and determining the optimal fasting plasma glucose (FPG) cutoff for diagnosis of hyperglycemia in the Chinese population. METHODS: We obtained the study population from 2007-2008 China Diabetes and Metabolic Disorders Study...
June 22, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28640916/severe-hearing-impairment-and-risk-of-depression-a-national-cohort-study
#17
So Young Kim, Hyung-Jong Kim, Eun-Kyu Park, Jiwon Joe, Songyong Sim, Hyo Geun Choi
OBJECTIVE: Hearing impairment is suggested to be associated with depression in the elderly. The present study evaluated the risk of depression after hearing impairment in all age groups matched by age, sex, income, and region of residence. METHODS: The Korean Health Insurance Review and Assessment Service-National Patient Samples were collected for a period from 2002 to 2013. Hearing impairment was defined as a hearing threshold ≥ 60 dB in both ears or as ≥ 80 dB in one ear and ≥ 40 dB in one ear...
2017: PloS One
https://www.readbyqxmd.com/read/28640896/beneficial-effects-of-a-gait-used-while-wearing-a-kimono-to-decrease-the-knee-adduction-moment-in-healthy-adults
#18
Susumu Ota, Yukari Ogawa, Hiroki Ota, Tomoya Fujiwara, Tadashi Sugiyama, Akira Ochi
The knee adduction moment (KAM) relates to medial knee osteoarthritis (OA). Several gait modifications to reduce the KAM for the prevention of knee OA have been studied. Most of the modifications, however, involve voluntary changes in leg alignment. Here we investigated the biomechanical effects for reducing the KAM of a walking style with a small trunk rotation and arm swing gait, which is a natural walking style used while wearing a kimono (Nanba walk) that shifts the ground reaction force toward the stance leg (reduced lever arm)...
2017: PloS One
https://www.readbyqxmd.com/read/28640812/challenges-in-preparing-and-implementing-a-clinical-trial-at-field-level-in-an-ebola-emergency-a-case-study-in-guinea-west-africa
#19
Sara Carazo Perez, Elin Folkesson, Xavier Anglaret, Abdoul-Habib Beavogui, Emmanuel Berbain, Alseny-Modet Camara, Evelyn Depoortere, Annabelle Lefevre, Piet Maes, Kristian Nødtvedt Malme, Jean-Marie Denis Malvy, Sien Ombelet, Geertrui Poelaert, Daouda Sissoko, Alexis Tounkara, Pierre Trbovic, Pascal Piguet, Annick Antierens
During the large Ebola outbreak that affected West Africa in 2014 and 2015, studies were launched to evaluate potential treatments for the disease. A clinical trial to evaluate the effectiveness of the antiviral drug favipiravir was conducted in Guinea. This paper describes the main challenges of the implementation of the trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, we explored the aspects of the community's communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28640793/intraoperative-computed-tomography-ct-for-treating-giant-carotid-intracavernous-aneurysms
#20
Zhe Xue, Fuyu Wang, Zhenghui Sun, Hui Zhang, Chen Wu, Dongsheng Kong, Bainan Xu
BACKGROUND Giant carotid intracavernous aneurysm refers to those lesions larger than 2.5 cm and derived from a cavernous segment, accounting for about 30% of all intracranial tumors. Dynamic CT perfusion imaging (PCT) is a common method recently employed to evaluate cerebral perfusion. This study investigated the efficacy and clinical application of intraoperative CT in the surgery for giant symptomatic carotid intracavernous aneurysm. MATERIAL AND METHODS A retrospective analysis was performed on 23 cases with giant symptomatic carotid intracavernous aneurysm...
June 22, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
keyword
keyword
437
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"