keyword
https://read.qxmd.com/read/38092429/do-some-patients-receive-unnecessary-parenteral-nutrition-after-pancreatoduodenectomy-results-from-an-international-multicentre-study
#21
JOURNAL ARTICLE
Thomas B Russell, Peter L Labib, Paula Murphy, Fabio Ausania, Elizabeth Pando, Keith J Roberts, Ambareen Kausar, Vasileios K Mavroeidis, Gabriele Marangoni, Sarah C Thomasset, Adam E Frampton, Pavlos Lykoudis, Manuel Maglione, Nassir Alhaboob, Hassaan Bari, Andrew M Smith, Duncan Spalding, Parthi Srinivasan, Brian R Davidson, Ricky H Bhogal, Daniel Croagh, Ismael Dominguez, Rohan Thakkar, Dhanny Gomez, Michael A Silva, Pierfrancesco Lapolla, Andrea Mingoli, Alberto Porcu, Nehal S Shah, Zaed Z R Hamady, Bilal Al-Sarrieh, Alejandro Serrablo, Somaiah Aroori
BACKGROUNDS/AIMS: After pancreatoduodenectomy (PD), an early oral diet is recommended; however, the postoperative nutritional management of PD patients is known to be highly variable, with some centers still routinely providing parenteral nutrition (PN). Some patients who receive PN experience clinically significant complications, underscoring its judicious use. Using a large cohort, this study aimed to determine the proportion of PD patients who received postoperative nutritional support (NS), describe the nature of this support, and investigate whether receiving PN correlated with adverse perioperative outcomes...
December 14, 2023: Annals of Hepato-Biliary-Pancreatic Surgery
https://read.qxmd.com/read/38062603/predictive-factors-of-postoperative-pancreatic-fistula-in-geriatric-patients-undergoing-pancreatoduodenectomy-for-periampullary-malignancy
#22
JOURNAL ARTICLE
Cengiz Ceylan, Huseyin Kocaaslan, Necip Tolga Baran, Mehmet Kulus, Kutay Saglam, Cemalettin Aydin
OBJECTIVE: To identify predictive factors associated with the occurrence of postoperative pancreatic fistula (POPF) following pancreatoduodenectomy (PD) in an increasingly geriatric population. STUDY DESIGN: Observational study. Place and Duration of the Study: Department of General Surgery, Inonu University, Malatya, Turkey, from January 2010 to April 2022. METHODOLOGY: Demographic and clinicopathological data of 74 geriatric patients who underwent PD for periampullary tumours in the clinic at Inonu University were retrieved from the patient database...
December 2023: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://read.qxmd.com/read/38043645/a-multi-institutional-safety-and-feasibility-study-exploring-the-use-of-hydrogel-to-create-spatial-separation-between-the-pancreas-and-duodenum-in-patients-with-pancreatic-cancer
#23
JOURNAL ARTICLE
Amol Kumar Narang, Theodore S Hong, Kai Ding, Joseph Herman, Jeffrey Meyer, Elizabeth Thompson, Manoop S Bhutani, Kumar Krishnan, Brenna Casey, Euin Ji Shin, Eugene J Koay
INTRODUCTION: The administration of dose-escalated radiation for pancreatic adenocarcinoma remains challenging due to the proximity of dose-limiting stomach and bowel, particularly the duodenum for pancreatic head tumors. We explore whether endoscopic injection of a temporary, absorbable hydrogel into the pancreatico-duodenal (PD) groove is safe and feasible for the purpose of increasing spatial separation between pancreatic head tumors and the duodenum. METHODS: Six patients with localized pancreatic adenocarcinoma underwent endoscopic injection of hydrogel into the PD groove...
December 1, 2023: Practical Radiation Oncology
https://read.qxmd.com/read/38036696/postoperative-complications-after-pancreatoduodenectomy-for-malignancy-results-from-the-recurrence-after-whipple-s-raw-study
#24
JOURNAL ARTICLE
Thomas B Russell, Peter L Labib, Jemimah Denson, Adam Streeter, Fabio Ausania, Elizabeth Pando, Keith J Roberts, Ambareen Kausar, Vasileios K Mavroeidis, Gabriele Marangoni, Sarah C Thomasset, Adam E Frampton, Pavlos Lykoudis, Manuel Maglione, Nassir Alhaboob, Hassaan Bari, Andrew M Smith, Duncan Spalding, Parthi Srinivasan, Brian R Davidson, Ricky H Bhogal, Daniel Croagh, Ismael Dominguez, Rohan Thakkar, Dhanny Gomez, Michael A Silva, Pierfrancesco Lapolla, Andrea Mingoli, Alberto Porcu, Nehal S Shah, Zaed Z R Hamady, Bilal A Al-Sarrieh, Alejandro Serrablo, Somaiah Aroori
BACKGROUND: Pancreatoduodenectomy (PD) is associated with significant postoperative morbidity. Surgeons should have a sound understanding of the potential complications for consenting and benchmarking purposes. Furthermore, preoperative identification of high-risk patients can guide patient selection and potentially allow for targeted prehabilitation and/or individualized treatment regimens. Using a large multicentre cohort, this study aimed to calculate the incidence of all PD complications and identify risk factors...
November 1, 2023: BJS Open
https://read.qxmd.com/read/38022022/occurrence-of-immune-thrombocytopenic-purpura-following-enucleation-of-a-neuroendocrine-tumor-of-the-head-of-the-pancreas
#25
Mohamed Jazeer, Chaminda Garusinghe
Neuroendocrine tumors are growths occurring in various organs including the pancreas which contain endocrine tissue. Pancreatic neuroendocrine tumors are rare in occurrence with an incidence of <1 per 100,000 individuals. But the incidence is rising and the said tumors are becoming more common in the world. Herein we report a case of a 49-year-old female with a background history of poorly controlled type 2 diabetes mellitus for 7 years, dyslipidemia, and bronchial asthma for 19 years on regular inhaler therapy presenting with a history of back pain for 3 months duration...
October 2023: Curēus
https://read.qxmd.com/read/38021569/bilateral-external-oblique-intercostal-catheter-for-post-operative-analgesia-after-open-pancreaticoduodenectomy-a-case-report
#26
Weng Ken Chan, Kok Wang Tan, Kok Peng Chong, Angelina Chia Chia Lim, Iskandar Khalid
Open pancreaticoduodenectomy, also known as Whipple surgery, is a complex and painful procedure that requires a multi-modal analgesic approach for successful post-operative rehabilitation and recovery. While thoracic epidural analgesia (TEA) remains the gold standard for pain relief after open upper abdominal surgery, it carries many risks that may outweigh the potential benefits of the technique. Furthermore, in laparoscopic converted to open pancreaticoduodenectomy cases, post-operative placement of a thoracic epidural catheter is inconvenient to the patient due to pain and positioning...
October 2023: Curēus
https://read.qxmd.com/read/37995202/rare-cause-of-gastrointestinal-bleeding-a-case-report-of-pancreatic-arteriovenous-malformation
#27
JOURNAL ARTICLE
Thanh Huu Nguyen, Lam Tung Tran, Binh Canh Nguyen, Nga Thi Dinh, Hoai Thu Mai, Quang Ngoc Minh Pham, Linh Van Ho, Thai Doan Ky, Tung Lam Nguyen
BACKGROUND Arteriovenous malformation is an unusual cause of gastrointestinal bleeding, particularly in the pancreas. A definitive treatment strategy is not yet established. CASE REPORT We present the case of a 37-year-old man with underlying hypertension and no significant family history who presented with a 3-month history of intermittent epigastric pains and unintentional weight loss of 5 kg in 2 months. The upper endoscopy showed a large duodenal ulcer, which was uncontrolled with a standard dose of proton pump inhibitors...
November 23, 2023: American Journal of Case Reports
https://read.qxmd.com/read/37969830/near-5-year-survival-in-metastatic-pancreatic-cancer-patient-with-ros1-rearrangement-her2-amplification-and-kras-g12c-mutation-a-case-report
#28
Kaan Y Balta, Stephan Welch, Mark Vincent, Daniel Breadner
BACKGROUND: Pancreatic cancer is a significant cause of cancer-related deaths in Canada. Although it is less common than other cancers, the mortality rate has remained high and stable since 1984, with a five-year net survival rate being the lowest of 23 reported cancers. The limited options for detection and treatment contribute to the high mortality rate. A developing area of treatment is tumour site agnostic targeted therapy, where patients' cancer is treated based on genomic alterations that are amenable to targeted agents, regardless of where the tumour originated...
October 31, 2023: Journal of Gastrointestinal Oncology
https://read.qxmd.com/read/37954694/a-rare-case-of-metastatic-ampullary-adenocarcinoma-following-the-whipple-procedure
#29
Aboud Kaliounji, Haya Kaliounji, Michael A Farraj, Nischal Sharma, Samy I McFarlane
Ampullary carcinoma is an extremely rare type of gastrointestinal cancer that originates at the ampulla of Vater, distal to the junction between the pancreatic duct and the common bile duct (CBD). There are three subtypes depending on the histological findings: pancreatobiliary, intestinal, and mixed subtype. Symptoms can mimic other pathologies related to biliary obstruction, such as jaundice, diarrhea, steatorrhea, and weight loss. In this report, we present a case of a 40-year-old male who presented with painless jaundice and dizziness...
October 2023: Curēus
https://read.qxmd.com/read/37942046/unusual-paraneoplastic-syndromes-in-pancreatic-cancer-a-case-report-of-lambert-eaton-myasthenic-syndrome-lems-associated-with-intraductal-papillary-mucinous-cancer-of-the-pancreas
#30
Athanasios Zamparas, Torsten Herzog, Sarah Förster, Ines Siglienti, Waldemar Uhl, Johanna Strotmann, Philipp Höhn
BACKGROUND: Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder of the neuromuscular junction. It can occur as a paraneoplastic disorder associated with various types of carcinomas, usually small cell lung cancer or as an autoimmune disease. LEMS can be misdiagnosed as myasthenia gravis or as an oncological sequela, causing delays in diagnosis. We present a rare case of a male adult with confirmed LEMS occurring with pancreatic carcinoma. CASE DESCRIPTION: A 66-year-old man presented with a newly diagnosed pancreatic tumor...
2023: AME Case Reports
https://read.qxmd.com/read/37941365/dr-allen-oldfather-whipple-1881-1963-namesake-of-the-pancreaticoduodenectomy
#31
JOURNAL ARTICLE
Ashton D Hall, Julia E Kumar, Jan P Mazur, Alexander J Bondoc, Bruce F Giffin, Whitney K Bryant
Allen O. Whipple was an American surgeon who popularized the pancreaticoduodenectomy (Whipple procedure) for periampullary cancer, which remains the gold standard for pancreatic tumor resections. Whipple was educated at Princeton University (B.S., 1904) and Columbia University College of Physicians and Surgeons (M.D., 1908). He swiftly ascended the academic ranks, culminating in his appointment as Professor of Surgery at Columbia and Director of Surgical Services at Presbyterian Hospital in 1921. Whipple published three criteria (Whipple's triad) for evaluating hyperinsulinism secondary to pancreatic insulinoma...
November 9, 2023: Journal of Medical Biography
https://read.qxmd.com/read/37941362/racial-and-socioeconomic-differences-and-surgical-outcomes-in-pancreaticoduodenectomy-patients-a-systematic-review-of-high-versus-low-volume-hospitals-in-the-united-states
#32
REVIEW
Mohammad Ikram, Chan Shen, Colette R Pameijer
BACKGROUND: Pancreaticoduodenectomy (PD) is associated with better outcomes in high-volume hospitals. However, it is unknown whether and to what extent the improved performance of high-volume hospitals may be associated with racial and socioeconomic factors, which have been shown to impact operative and postoperative outcomes in major surgeries. This review aims to identify the differences in racial and socioeconomic characteristics of patients who underwent PD surgery in high- and low-volume hospitals...
November 8, 2023: American Surgeon
https://read.qxmd.com/read/37927925/current-progress-in-robotic-hepatobiliary-and-pancreatic-surgery-at-a-high-volume-center
#33
REVIEW
Frances N McCarron, Dionisios Vrochides, John B Martinie
There has been steady growth in the adoption of robotic HPB procedures world-wide over the past 20 years, but most of this increase has occurred only recently. Not surprisingly, the vast majority of robotics has been in the United States, with very few, select centers of adoption in Italy, South Korea, and Brazil, to name a few. We began our robotic HPB program in 2008, well before almost all other centers in the world, with the most notable exception of Giullianotti and colleagues. Our program began gradually, with smaller cases carefully selected to optimize the strengths of the original robotic platform and included complex biliary and pancreatic resections...
November 2023: Annals of Gastroenterological Surgery
https://read.qxmd.com/read/37925662/approach-to-the-patient-insulinoma
#34
JOURNAL ARTICLE
Johannes Hofland, Julie C Refardt, Richard A Feelders, Emanuel Christ, Wouter W de Herder
Insulinomas are hormone-producing pancreatic neuroendocrine neoplasms (panNEN) with an estimated incidence of 1-4 cases per million per year. Extrapancreatic insulinomas are extremely rare. Most insulinomas present with Whipple's triad: 1) symptoms, signs, or both consistent with hypoglycemia, 2) a low plasma glucose measured at the time of the symptoms and signs, and 3) relief of symptoms and signs when the glucose is raised to normal. Non-metastatic insulinomas are nowadays referred to as "indolent" and metastatic insulinomas as "aggressive"...
October 31, 2023: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/37881394/predictors-of-in-hospital-mortality-following-pancreatectomy
#35
JOURNAL ARTICLE
Anna Axentiev, Artem Shmelev, Steven C Cunningham
BACKGROUND: In-hospital mortality rates following all types of pancreatic resections (PRs) have decreased over recent decades. Our aim was to identify predictors of in-hospital mortality following pancreatic resection. METHODS: All patients undergoing pancreatic resection were sampled from the National Inpatient Sample (NIS) in the years 2007-2012. Predictors of in-hospital mortality were identified and incorporated into a binary logistic regression model. RESULTS: A total of 111,568 patients underwent pancreatectomy...
September 2023: Curēus
https://read.qxmd.com/read/37842463/frantz-s-tumor-in-focus-the-tale-of-a-34-year-old-yemeni-female-patient
#36
Saleh A Ba-Shammakh, Bourhan Alrayes, Uwise Awaisheh, Hisham Hamad, Mohammad S Al-Qannas, Hamza M Abu-Obead
A solid pseudopapillary tumor (SPT) of the pancreas, which mainly occurs in young women, is an uncommon pancreatic tumor that often presents diagnostic and therapeutic dilemmas. This case study discusses the symptoms and treatment approach for a 34-year-old woman from Yemen diagnosed with SPT. The patient was diagnosed through abdominal and pelvis CT scan, followed by ultrasound-guided biopsy confirming the presence of SPPT. Management through the Whipple procedure and portal vein reconstruction proved successful, with no recurrence or metastasis noted in a year-long follow-up...
September 2023: Curēus
https://read.qxmd.com/read/37810002/utility-of-intraoperative-pathology-consultations-of-whipple-resection-specimens-and-their-impact-on-final-margin-status
#37
JOURNAL ARTICLE
Niloofar Sina, Ekaterina Olkhov-Mitsel, Lina Chen, Paul Karanicolas, Laibao Sun, Preeya Roopchand, Corwyn Rowsell, Tra Truong
The resection margin status is a significant surgical prognostic factor for the long-term outcomes of patients undergoing pancreaticoduodenectomy (Whipple procedure). As a result, surgeons frequently rely on intraoperative consults (IOCs) involving frozen sections to evaluate margin clearance during these resections. Nevertheless, the impact of this practice on final margin status and long-term outcomes remains a topic of debate. This study aimed to assess the impact of IOCs on the clearance rate of resection margins following Whipple procedure and distal pancreatectomy...
September 2023: Heliyon
https://read.qxmd.com/read/37783471/-surgical-resection-and-survival-of-clear-cell-renal-cancer-metastases-to-the-pancreas
#38
JOURNAL ARTICLE
Germán E Sánchez-Morales, Jorge L Osorio-Serrano, Alan Guerrero-Gómez, Carlos Chan, Ismael Domínguez-Rosado
INTRODUCTION: Pancreas is considered one of the organs most frequently affected by recurrence after nephrectomy secondary to renal cell carcinoma reporting an incidence of 20%, 85% of these occur within the first 3 years. OBJECTIVE: The objective of the study is to evaluate overall survival and disease-free survival in patients with renal cancer and pancreatic metastases who underwent surgical treatment. METHODS: A retrospective cross-sectional study of patients with histological diagnosis of renal cancer associated with pancreatic metastasis was performed and included those treated by pancreatoduodenectomy or distal pancreatectomy during the period 1987-2020...
October 2, 2023: Cirugia y Cirujanos
https://read.qxmd.com/read/37772445/evolution-of-laparoscopic-pancreaticoduodenectomy-at-westmead-hospital
#39
JOURNAL ARTICLE
Ji Chen, Helen Pham, Crystal Li, Christopher B Nahm, Emma Johnston, Michael John Hollands, Tony Pang, Henry Pleass, Vincent Lam, Arthur Richardson, Lawrence Yuen
BACKGROUND: Despite its proposed benefits, laparoscopic pancreaticoduodenectomy (LPD) has not been widely adopted due to its technical complexity and steep learning curve. The aim of this study was to report a single surgeon's experience in the stepwise implementation of LPD and evolution of technique over a nine-year period in a moderate-high volume unit. METHODS: Carefully selected patients underwent LPD initially by hybrid approach (laparoscopic resection and open reconstruction), which evolved into a total LPD (laparoscopic resection and reconstruction)...
September 29, 2023: ANZ Journal of Surgery
https://read.qxmd.com/read/37772085/from-the-borders-edge-to-the-brink-of-death-a-case-of-a-traumatic-pancreatic-injury-and-whipple-procedure-in-the-rio-grande-valley
#40
Valentine S Alia, Ed W Alvarado, Edward M Diaz, Daniel Albo, Roger Galindo
The traumatic pancreatoduodenectomy, also known as the traumatic Whipple, is a specialized surgical procedure often reserved for extreme cases in which an individual suffers traumatic injuries to the pancreas, duodenum, or periampullary structures. Traditionally, a Whipple procedure is a complex surgery involving the removal of the head of the pancreas, duodenum, and a portion of both the bile duct and stomach, for the management of pancreatic head cancer. In underserved communities where limited access to healthcare is coupled with a higher incidence of trauma, the lack of specialized and supportive care for patients suffering from pancreatic injuries may lead to an increased morbidity and mortality rate...
December 2023: Trauma Case Reports
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