keyword
MENU ▼
Read by QxMD icon Read
search

Brodmann

keyword
https://www.readbyqxmd.com/read/27899123/a-functional-magnetic-resonance-imaging-investigation-of-visual-hallucinations-in-the-human-striate-cortex
#1
Hina Abid, Fayyaz Ahmad, Soo Y Lee, Hyun W Park, Dongmi Im, Iftikhar Ahmad, Safee U Chaudhary
PURPOSE: Human beings frequently experience fear, phobia, migraine and hallucinations, however, the cerebral mechanisms underpinning these conditions remain poorly understood. Towards this goal, in this work, we aim to correlate the human ocular perceptions with visual hallucinations, and map them to their cerebral origins. METHODS: An fMRI study was performed to examine the visual cortical areas including the striate, parastriate and peristriate cortex in the occipital lobe of the human brain...
November 29, 2016: Behavioral and Brain Functions: BBF
https://www.readbyqxmd.com/read/27899117/assistive-products-and-the-sustainable-development-goals-sdgs
#2
Emma Tebbutt, Rebecca Brodmann, Johan Borg, Malcolm MacLachlan, Chapal Khasnabis, Robert Horvath
The Sustainable Development Goals (SDGs) have placed great emphasis on the need for much greater social inclusion, and on making deliberate efforts to reach marginalized groups. People with disabilities are often marginalized through their lack of access to a range of services and opportunities. Assistive products can help people overcome impairments and barriers enabling them to be active, participating and productive members of society. Assistive products are vital for people with disabilities, frailty and chronic illnesses; and for those with mental health problems, and gradual cognitive and physical decline characteristic of aging populations...
November 29, 2016: Globalization and Health
https://www.readbyqxmd.com/read/27884212/angiotensin-converting-enzyme-2-is-reduced-in-alzheimer-s-disease-in-association-with-increasing-amyloid-%C3%AE-and-tau-pathology
#3
Patrick Gavin Kehoe, Steffenny Wong, Noura Al Mulhim, Laura Elyse Palmer, J Scott Miners
BACKGROUND: Hyperactivity of the classical axis of the renin-angiotensin system (RAS), mediated by angiotensin II (Ang II) activation of the angiotensin II type 1 receptor (AT1R), is implicated in the pathogenesis of Alzheimer's disease (AD). Angiotensin-converting enzyme-2 (ACE-2) degrades Ang II to angiotensin 1-7 (Ang (1-7)) and counter-regulates the classical axis of RAS. We have investigated the expression and distribution of ACE-2 in post-mortem human brain tissue in relation to AD pathology and classical RAS axis activity...
November 25, 2016: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/27882449/diametrical-relationship-between-gray-and-white-matter-volumes-in-autism-spectrum-disorder-and-schizophrenia
#4
Serge A Mitelman, Marie-Cecile Bralet, M Mehmet Haznedar, Eric Hollander, Lina Shihabuddin, Erin A Hazlett, Monte S Buchsbaum
Autism spectrum disorders and schizophrenia have been variously characterized as separate nosological entities with overlapping deficits in social cognition or diametrical extremes of a phenotypic continuum. This study aimed to determine how these models apply to comparative morphometric data. MRI scans of the brain were obtained in 49 subjects with schizophrenia, 20 subjects with autism and 39 healthy controls. Images were parcellated into 40 Brodmann areas and entered into repeated-measures ANOVA for between-group comparison of global and localized gray and white matter volumes...
November 23, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27873015/muscarinic-receptor-binding-changes-in-postmortem-parkinson-s-disease
#5
Caitlin McOmish, Geoff Pavey, Catriona McLean, Malcolm Horne, Brian Dean, Elizabeth Scarr
Parkinson's disease (PD) is a devastating disorder, affecting approximately 2% of people aged 60 and above. It is marked by progressive neurodegeneration that has long been known to impact dopaminergic cells and circuits, but more recently the acetylcholine system has also been implicated in the complex aetiology and symptomatology of the disease. While broad changes in cholinergic markers have been described, insight into the contribution of specific acetylcholine receptors is less clear. To address this important unknown, in this study we performed [(3)H] pirenzepine, [(3)H] 4DAMP, and [(3)H] AF-DX 384 in situ radioligand binding on postmortem tissues from Brodmann's area 6, 9, 46, and the caudate putamen, from PD and matched controls to detect muscarinic M1, M3, and M1/2/4 receptors, respectively...
November 21, 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27870461/sexual-dimorphism-of-broca-s-region-more-gray-matter-in-female-brains-in-brodmann-areas-44-and-45
#6
Florian Kurth, Lutz Jancke, Eileen Luders
Although a sexual dimorphism in brain structure is generally well established, evidence for sex differences in Brodmann areas (BA) 44 and 45 is inconclusive. This may be due to the difficulty of accurately defining BA 44 and BA 45 in magnetic resonance images, given that these regions are variable in their location and extent and that they do not match well with macroanatomic landmarks. Here we set out to test for possible sex differences in the local gray matter of BA 44/45 by integrating imaging-based signal intensities with cytoarchitectonically defined tissue probabilities in a sample of 50 male and 50 female subjects...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27848280/intra-arterial-thrombolysis-of-digital-artery-occlusions-in-a-patient-with-polycythemia-vera
#7
Philipp Jud, Franz Hafner, Thomas Gary, Leyla Ghanim, Rainer Lipp, Marianne Brodmann
There are limited therapeutic options for the resolution of digital artery occlusions. Intra-arterial thrombolysis with anticoagulative and thrombolytic drugs successfully restored the blood flow in the affected digital arteries.
November 18, 2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27843695/a-machine-learning-approach-to-identify-functional-biomarkers-in-human-prefrontal-cortex-for-individuals-with-traumatic-brain-injury-using-functional-near-infrared-spectroscopy
#8
Nader Karamzadeh, Franck Amyot, Kimbra Kenney, Afrouz Anderson, Fatima Chowdhry, Hadis Dashtestani, Eric M Wassermann, Victor Chernomordik, Claude Boccara, Edward Wegman, Ramon Diaz-Arrastia, Amir H Gandjbakhche
BACKGROUND: We have explored the potential prefrontal hemodynamic biomarkers to characterize subjects with Traumatic Brain Injury (TBI) by employing the multivariate machine learning approach and introducing a novel task-related hemodynamic response detection followed by a heuristic search for optimum set of hemodynamic features. To achieve this goal, the hemodynamic response from a group of 31 healthy controls and 30 chronic TBI subjects were recorded as they performed a complexity task...
November 2016: Brain and Behavior
https://www.readbyqxmd.com/read/27833164/periodontal-tactile-input-activates-the-prefrontal-cortex
#9
Nobuaki Higaki, Takaharu Goto, Tetsuo Ichikawa
The prefrontal cortex (PFC) plays a role in complex cognitive behavioural planning, decision-making, and social behaviours. However, the effects of sensory integration during motor tasks on PFC activation have not been studied to date. Therefore, we investigated the effect of peripheral sensory information and external information on PFC activation using functional near-infrared spectroscopy (fNIRS). Cerebral blood flow (CBF) was increased around bilateral Brodmann areas 46 and 10 during visual and auditory information integration during an occlusal force (biting) task...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27832593/parietal-area-ba7-integrates-motor-programs-for-reaching-grasping-and-bimanual-coordination
#10
Ada Le, Mike Vesia, Xiaogang Yan, J Douglas Crawford, Matthias Niemeier
Skillful interaction with the world requires that the brain uses a multitude of sensorimotor programs and subroutines such as for reaching, grasping, and the coordination of the two body halves. However, it is unclear how these programs operate together. Networks for reaching, grasping, and bimanual coordination might converge in common brain areas. For example, Brodmann Area 7 (BA7) is known to activate in disparate tasks involving the three types of movements separately. Here we asked whether BA7 plays a key role in integrating coordinated reach-to-grasp movements for both arms together...
November 9, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27813530/involvement-of-infralimbic-prefrontal-cortex-but-not-lateral-habenula-in-dopamine-attenuation-after-chronic-mild-stress
#11
Jared L Moreines, Zoe L Owrutsky, Anthony A Grace
Emerging evidence supports a role for dopamine in major depressive disorder (MDD). We recently reported fewer spontaneously active ventral tegmental area (VTA) dopamine neurons (ie reduced dopamine neuron population activity) in the chronic mild stress (CMS) rodent model of MDD. In this study, we examine the role of two brain regions that have been implicated in MDD in humans, the infralimbic prefrontal cortex (ILPFC)-ie rodent homologue of Brodmann Area 25 (BA25), and the lateral habenula (LHb), in the CMS-induced attenuation of dopamine neuron activity...
November 4, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27806866/neurofunctional-differences-among-youth-with-and-at-varying-risk-for-developing-mania
#12
Jeffrey A Welge, Lawrence J Saliba, Jeffrey R Strawn, James C Eliassen, L Rodrigo Patino, Caleb M Adler, Wade Weber, Marguerite Reid Schneider, Drew H Barzman, Stephen M Strakowski, Melissa P DelBello, Robert K McNamara
OBJECTIVE: To examine prefrontal and amygdala activation during emotional processing in youth with or at varying risk for developing mania to identify candidate central prodromal risk biomarkers. METHOD: Four groups of medication-free adolescents (10-20 years old) participated: adolescents with first-episode bipolar I disorder (BP-I; n = 32), adolescents with a parent with bipolar disorder and a depressive disorder (at-risk depressed [ARD]; n = 32), healthy adolescents with a parent with bipolar disorder (at-risk healthy [ARH]; n = 32), and healthy adolescents with no personal or family history of psychiatric illness (healthy comparison [HC]; n = 32)...
November 2016: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27803994/neuronal-electrical-ongoing-activity-as-a-signature-of-cortical-areas
#13
Carlo Cottone, Camillo Porcaro, Andrea Cancelli, Elzbieta Olejarczyk, Carlo Salustri, Franca Tecchio
Brodmann's pioneering work resulted in the classification of cortical areas based on their cytoarchitecture and topology. Here, we aim at documenting that diverse cortical areas also display different neuronal electric activities. We investigated this notion in the hand-controlling sections of the primary somatosensory (S1) and motor (M1) areas, in both hemispheres. We identified S1 and M1 in 20 healthy volunteers by applying functional source separation (FSS) to their recorded electroencephalograms (EEG). Our results show that S1 and M1 can be clearly differentiated by their neuroelectric activities in both hemispheres and independently of the subject's state (i...
November 1, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27801890/changed-gene-expression-in-subjects-with-schizophrenia-and-low-cortical-muscarinic-m1-receptors-predicts-disrupted-upstream-pathways-interacting-with-that-receptor
#14
E Scarr, M Udawela, E A Thomas, B Dean
We tested the hypothesis that, compared with subjects with no history of psychiatric illness (controls), changes in gene expression in the dorsolateral prefrontal cortex from two subgroups of subjects with schizophrenia, one with a marked deficit in muscarinic M1 receptors (muscarinic receptor-deficit schizophrenia (MRDS)), would identify different biochemical pathways that would be affected by their aetiologies. Hence, we measured levels of cortical (Brodmann area 9) mRNA in 15 MRDS subjects, 15 subjects with schizophrenia but without a deficit in muscarinic M1 receptors (non-MRDS) and 15 controls using Affymetrix Exon 1...
November 1, 2016: Molecular Psychiatry
https://www.readbyqxmd.com/read/27771590/decreased-resting-state-metabolic-activity-in-frontopolar-and-parietal-brain-regions-is-associated-with-suicide-plans-in-depressed-individuals
#15
Kees van Heeringen, Guo-Rong Wu, Myriam Vervaet, Marie-Anne Vanderhasselt, Chris Baeken
Suicide plans are a major risk factor for suicide, which is a devastating outcome of depression. While structural and functional brain changes have been demonstrated in relation to suicidal thoughts and behaviour, brain mechanisms underlying suicide plans have not yet been studied. Here, we studied changes in regional cerebral metabolic activity in association with suicide plans in depressed individuals. Using (18)FDG-PET, a comparative study of regional cerebral glucose metabolism (rCMRglu) was carried out in depressed individuals with suicidal thoughts and suicide plans, depressed individuals with only suicidal thoughts, depressed individuals without suicide thoughts and plans, and healthy controls...
October 19, 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27770234/soluble-pre-fibrillar-tau-and-%C3%AE-amyloid-species-emerge-in-early-human-alzheimer-s-disease-and-track-disease-progression-and-cognitive-decline
#16
David J Koss, Glynn Jones, Anna Cranston, Heidi Gardner, Nicholas M Kanaan, Bettina Platt
Post-mortem investigations of human Alzheimer's disease (AD) have largely failed to provide unequivocal evidence in support of the original amyloid cascade hypothesis, which postulated deposition of β-amyloid (Aβ) aggregates to be the cause of a demented state as well as inductive to tau neurofibrillary tangles (NFTs). Conflicting evidence suggests, however, that Aβ plaques and NFTs, albeit to a lesser extent, are present in a substantial subset of non-demented individuals. Hence, a range of soluble tau and Aβ species has more recently been implicated as the disease-relevant toxic entities...
December 2016: Acta Neuropathologica
https://www.readbyqxmd.com/read/27742666/medial-reward-and-lateral-non-reward-orbitofrontal-cortex-circuits-change-in-opposite-directions-in-depression
#17
Wei Cheng, Edmund T Rolls, Jiang Qiu, Wei Liu, Yanqing Tang, Chu-Chung Huang, XinFa Wang, Jie Zhang, Wei Lin, Lirong Zheng, JunCai Pu, Shih-Jen Tsai, Albert C Yang, Ching-Po Lin, Fei Wang, Peng Xie, Jianfeng Feng
The first brain-wide voxel-level resting state functional connectivity neuroimaging analysis of depression is reported, with 421 patients with major depressive disorder and 488 control subjects. Resting state functional connectivity between different voxels reflects correlations of activity between those voxels and is a fundamental tool in helping to understand the brain regions with altered connectivity and function in depression. One major circuit with altered functional connectivity involved the medial orbitofrontal cortex Brodmann area 13, which is implicated in reward, and which had reduced functional connectivity in depression with memory systems in the parahippocampal gyrus and medial temporal lobe, especially involving the perirhinal cortex Brodmann area 36 and entorhinal cortex Brodmann area 28...
December 2016: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/27735901/-creatine-kinase-isoform-b-distribution-in-the-brain-in-schizophrenia
#18
O K Savushkina, E B Tereshkina, T A Prokhorova, E A Vorob'eva, I S Boksha, G Sh Burbaeva
AIM: To compare patterns of brain isoform creatine phosphokinase (CPK B) distributions in post-mortem brain from patients with schizophrenia (Sch) and patients with somatic diseases (controls). MATERIAL AND METHODS: Extracts of readily soluble and membrane-associated proteins were prepared from post-mortem samples of prefrontal cortex (Brodmann area 10), anterior (area 24) and posterior (area 23) cingulate cortex, hippocampus and cerebellum cortex from patients with Sch and control group (the samples were matched by age and postmortem interval)...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27733825/inferior-prefrontal-cortex-mediates-the-relationship-between-phosphatidylcholine-and-executive-functions-in-healthy-older-adults
#19
Marta K Zamroziewicz, Chris E Zwilling, Aron K Barbey
Objectives: This study examines the neural mechanisms that mediate the relationship between phosphatidylcholine and executive functions in cognitively intact older adults. We hypothesized that higher plasma levels of phosphatidylcholine are associated with better performance on a particular component of the executive functions, namely cognitive flexibility, and that this relationship is mediated by gray matter structure of regions within the prefrontal cortex (PFC) that have been implicated in cognitive flexibility...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27733180/the-effects-of-linagliptin-on-endothelial-function-and-global-arginine-bioavailability-ratio-in-coronary-artery-disease-patients-with-early-diabetes-study-protocol-for-a-randomized-controlled-trial
#20
Norbert J Tripolt, Felix Aberer, Regina Riedl, Barbara Hutz, Jasmin Url, Gudrun Dimsity, Andreas Meinitzer, Tatjana Stojakovic, Ronald Hödl, Marianne Brodmann, Franz Hafner, Harald Sourij
BACKGROUND: Patients with type 2 diabetes (T2DM) are at increased risk for macrovascular events as well as for microvascular complications. There is evidence that in patients with coronary artery disease (CAD), about 35 % suffer from manifest T2DM. Early glucose-lowering intervention in subjects with T2DM has been demonstrated to be beneficial in terms of cardiovascular risk reduction. But thus far, no data are available regarding investigating the impact of linagliptin treatment in patients with early diabetes on cardiovascular endpoints or surrogate parameters...
October 13, 2016: Trials
keyword
keyword
43689
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"