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Muscular injuries

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https://www.readbyqxmd.com/read/28207424/skeletal-muscle-wasting-new-role-of-nonclassical-renin-angiotensin-system
#1
Claudio Cabello-Verrugio, Juan C Rivera, Dominga Garcia
PURPOSE OF REVIEW: Skeletal muscle can be affected by many physiological and pathological conditions that contribute to the development of muscle weakness, including skeletal muscle loss, inflammatory processes, or fibrosis. Therefore, research into therapeutic treatment alternatives or alleviation of these effects on skeletal muscle is of great importance. RECENT FINDINGS: Recent studies have shown that angiotensin (1-7) [Ang-(1-7)] - a vasoactive peptide of the nonclassical axis in the renin-angiotensin system (RAS) - and its Mas receptor are expressed in skeletal muscle...
February 16, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28203599/surgical-management-of-rectus-femoris-avulsion-among-professional-soccer-players
#2
Bertrand Sonnery-Cottet, Nuno Camelo Barbosa, Sanesh Tuteja, Roland Gardon, Matt Daggett, Damien Monnot, Charles Kajetanek, Mathieu Thaunat
BACKGROUND: Rectus femoris injuries are common among athletes, especially in kicking sports such as soccer; however, proximal rectus femoris avulsions in athletes are a relatively rare entity. PURPOSE/HYPOTHESIS: The purpose of this study was to describe and report the results of an original technique of surgical excision of the proximal tendon remnant followed by a muscular suture repair. Our hypothesis was that this technique limits the risk of recurrence in high-level athletes and allows for rapid recovery without loss of quadriceps strength...
January 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28199538/analysis-of-factors-associated-with-rhytidectomy-malpractice-litigation-cases
#3
Aron Kandinov, Sean Mutchnick, Vaibhuv Nangia, Peter F Svider, Giancarlo F Zuliani, Mahdi A Shkoukani, Michael A Carron
Importance: This study investigates the financial burden of medical malpractice litigation associated with rhytidectomies, as well as factors that contribute to litigation and poor defendant outcomes, which can help guide physician practices. Objective: To comprehensively evaluate rhytidectomy malpractice litigation. Data Sources and Study Selection: Jury verdict and settlement reports related to rhytidectomy malpractice litigations were obtained using the Westlaw Next database...
February 9, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28199219/clinical-applications-of-near-infrared-diffuse-correlation-spectroscopy-and-tomography-for-tissue-blood-flow-monitoring-and-imaging
#4
Yu Shang, Ting Li, Guoqiang Yu
Near-infrared (NIR) light enables the deep tissue investigation of microvascular hemodynamics. Blood flow is one such available observable promoting a wealth of physiological insight both individually and in combination with other metrics. Diffuse correlation spectroscopy (DCS) and, to a lesser extent, diffuse correlation tomography (DCT), have received interest over the past two decades as noninvasive methods for tissue blood flow measurement and imaging. DCS employs coherent point-illumination NIR light to penetrate deep tissues and commonly uses avalanche photodiodes to detect temporal speckle fluctuations of the diffuse light in a single speckle area of tissue surface, which are sensitive to the motions of red blood cells in the microvasculature of the detected tissue volume...
February 15, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28194559/selenium-deficiency-induced-injury-in-chicken-muscular-stomach-by-downregulating-selenoproteins
#5
Xiaodan Huang, Bin Sun, Jiuli Zhang, Yuhong Gao, Guangxing Li, Ying Chang
The aim of the present study was to examine the effect of selenium (Se) deficiency on the expression of selenoproteins in chicken muscular stomach and to detect the correlation of selenoproteins with muscular stomach injuries. One-day-old broiler chickens were maintained for 55 days on a normal diet (0.2 mg/kg) or a Se-deficient diet (0.033 mg Se/kg). The expression levels of 25 selenoproteins, heat shock proteins (HSPs), and inflammatory factors were then examined by real-time PCR. Following this, the correlation between selenoproteins, HSPs, and inflammatory factors was analyzed by principal component analysis (PCA)...
February 13, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28188471/visualization-of-vascular-injuries-in-extremity-trauma
#6
Kwitae Chong, Chenfanfu Jiang, Daniel Ram, Anand Santhanam, Demetri Terzopoulos, Peyman Benharash, Erik Dutson, Joseph Teran, Jeff D Eldredge
A tandem of particle-based computational methods is adapted to simulate injury and hemorrhage in the human body. In order to ensure anatomical fidelity, a three-dimensional model of a targeted portion of the human body is reconstructed from a dense sequence of CT scans of an anonymized patient. Skin, bone and muscular tissue are distinguished in the imaging data and assigned with their respective material properties. An injury geometry is then generated by simulating the mechanics of a ballistic projectile passing through the anatomical model with the material point method...
February 11, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28188336/injuries-of-the-obturator-muscles-in-professional-soccer-players
#7
Manuel Wong-On, Antonio Turmo-Garuz, Rafael Arriaza, Jose Manuel Gonzalez de Suso, Luis Til-Perez, Xavier Yanguas-Leite, David Diaz-Cueli, Xavier Gasol-Santa
PURPOSE: Obturator externus and internus muscular tears are uncommon injuries. Only a few case reports exist, mainly in high-level athletes. Our aim is to describe a series of obturator externus and internus muscular tears in professional soccer players. METHODS: Injury data from four teams from the First Division of the Spanish Soccer League were collected over a total of four seasons. Any soccer player who sustained an injury to either the obturator externus or internus identified on magnetic resonance (MRI) was included...
February 10, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28173645/-peripheral-nerve-injury-in-lama2-related-congenital-muscular-dystrophy-patients
#8
X P Liang, S Wang, W Zhang, Y Yuan, J Ding, X Z Chang, C J Wei, J Y Liu, H Xiong
Objective: To explore the injury pattern and features of peripheral nerve in congenital muscular dystrophy patients caused by LAMA2 gene mutation. Method: Seventeen patients genetically or molecular pathologically diagnosed as LAMA2-related congenital muscular dystrophy were recruited in Peking University First Hospital between 2002 and 2015. All the patients received nerve conduction velocity (NCV) and needle electromyography tests. Clinical and laboratory examination data of the patients was retrospectively analyzed...
February 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28166884/the-sensitivity-of-a-military-based-occupational-fitness-test-of-muscular-strength
#9
Kane J Middleton, Greg L Carstairs, Joanne N Caldwell, Daniel C Billing, Ben Beck
The risk of low back pain and injury during manual materials handling is increased if personnel are not physically capable of safely performing such tasks. To establish predictive relationships and develop a test cut-score, 69 participants performed a critical military lifting task to a 1.5-m platform (pack lift) and two task-related predictive tests (box lift to 1.5 m and 1.3 m). The pack lift was strongly correlated with both the 1.5-m (R(2) = 0.85) and 1.3-m box lifts (R(2) = 0.82). Both tests had similar sensitivity (range 0...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28165873/overuse-physeal-injuries-in-youth-athletes
#10
Amanda Arnold, Charles A Thigpen, Paul F Beattie, Michael J Kissenberth, Ellen Shanley
CONTEXT: Despite rising awareness of the risks associated with sports participation, overuse injuries continue to increase in youth athlete populations. Physeal injuries are one type of overuse injury exclusive to pediatric populations that are often sustained during athletic practice or competition. Overuse physeal injuries are, in theory, preventable; however, little consensus has been reached surrounding the risk factors, prevention, and treatment strategies. OBJECTIVE: This systematic review summarizes the best available evidence concerning overuse physeal injuries in youth and adolescent athletes...
February 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28163176/effects-of-postconditioning-on-skeletal-muscle-injury-and-apoptosis-induced-by-partial-ischemia-and-reperfusion-in-rats
#11
José Alves Lintz, Marcelo Bellini Dalio, Luiz Fernando Tirapelli, Maurício Serra Ribeiro, Edwaldo Edner Joviliano, Carlos Eli Piccinato
PURPOSE: analyze the effects of ischemic postconditioning on skeletal muscle injury and apoptosis produced by partial ischemia and reperfusion in rats. MATERIALS AND METHODS: An experimental study was designed using 70 Wistar rats divided in three groups: Sham; Control - submitted to ischemia and reperfusion; Postconditioning - submitted to ischemia and reperfusion with ischemic postconditioning. Subgroups (n=10) were divided by duration of ischemia (four, five or six hours)...
February 2, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28159637/transcranial-magnetic-stimulation-tms-responses-elicited-in-hindlimb-muscles-as-an-assessment-of-synaptic-plasticity-in-spino-muscular-circuitry-after-chronic-spinal-cord-injury
#12
Hayk A Petrosyan, Valentina Alessi, Sue A Sisto, Mark Kaufman, Victor L Arvanian
Electromagnetic stimulation applied at the cranial level, i.e. transcranial magnetic stimulation (TMS), is a technique for stimulation and neuromodulation used for diagnostic and therapeutic applications in clinical and research settings. Although recordings of TMS elicited motor-evoked potentials (MEP) are an essential diagnostic tool for spinal cord injured (SCI) patients, they are reliably recorded from arm, and not leg muscles. Mid-thoracic contusion is a common SCI that results in locomotor impairments predominantly in legs...
January 31, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28155605/met-activating-genetically-improved-chimeric-factor-1-promotes-angiogenesis-and-hypertrophy-in-adult-myogenesis
#13
Flavio Ronzoni, Gabriele Ceccarelli, Ilaria Perini, Laura Benedetti, Daniela Galli, Francesca Mulas, Martina Balli, Giovanni Magenes, Riccardo Bellazzi, Gabriella Cusella De Angelis, Maurilio Sampaolesi
BACKGROUND: Myogenic progenitor cells (activated satellite cells) are able to express both HGF and its receptor cMet. After muscle injury, HGF-Met stimulation promotes activation and primary division of satellite cells. MAGIC-F1 (Met-Activating Genetically Improved Chimeric Factor-1) is an engineered protein that contains two human Met-binding domains that promotes muscle hypertrophy. MAGIC-F1 protects myogenic precursors against apoptosis and increases their fusion ability enhancing muscle differentiation...
February 1, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28149364/evaluating-injury-risk-in-first-and-second-league-professional-portuguese-soccer-muscular-strength-and-asymmetry
#14
Alberto Carvalho, Scott Brown, Eduardo Abade
Strength imbalances between the hamstrings and quadriceps are an essential predictor for hamstring strain in soccer. The study aimed to investigate and compare the muscle strength imbalances of professional soccer players of different performance levels. One hundred and fifty nine senior male professional soccer players from first (n = 75) and second league (n = 84) Portuguese clubs participated in this study. Muscle strength was evaluated with a REV9000 isokinetic dynamometer. Maximal peak torque data were used to calculate quadriceps and hamstrings strength during concentric and eccentric actions, bilateral asymmetry, conventional strength ratios and dynamic control ratios...
June 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28144407/knee-injuries-in-wrestlers-a-prospective-study-from-the-indian-subcontinent
#15
Shalini Agarwal, Ekta Mann
BACKGROUND: Wrestling is a very popular sport the world over and its popularity is rapidly increasing in India. However, due to its arduous nature it is associated with a high incidence of injuries. Out of all the injuries, those to the knee are one of the commonest injuries reported. OBJECTIVES: Our aim was to study the pattern of these injuries in the Indian wrestlers. METHODS: A prospective study was conducted involving 196 wrestlers who were followed up over a period of 2 years...
December 2016: Asian Journal of Sports Medicine
https://www.readbyqxmd.com/read/28133509/subchronic-oral-toxicity-study-of-acanthopanax-divaricatus-var-albeofructus-in-rats
#16
Myoung Jun Kim, Mi Ju Lee, Yong-Hoon Lee, Sun Hee Park, Duyeol Kim, Cheol Beom Park, Jin Seok Kang, Jong-Koo Kang
Acanthopanax divaricatus (Siebold & Zucc.) Seem. var. albeofructus (ADA), a traditional medical herb, has been used to treat arthritis and muscular injury, to strengthen muscle and bone, and to get vital energy. However, information regarding its toxicity is limited. ADA was administered by oral gavage to groups of rats at doses of 0 (control), 1,000, 1,500, 2,000, 2,500, and 3,000 mg/kg five times per week for 13 weeks. Mortality, clinical signs, body weights, food consumption, hematology, serum chemistry, urinalysis, organ weights, necropsy, histopathological finding, vaginal cytology, and sperm morphology were compared between control and ADA-treated groups...
January 2017: Toxicological Research
https://www.readbyqxmd.com/read/28131694/neer-award-2016-reduced-muscle-degeneration-and-decreased-fatty-infiltration-after-rotator-cuff-tear-in-a-poly-adp-ribose-polymerase-1-parp-1-knock-out-mouse-model
#17
Michael B Kuenzler, Katja Nuss, Agnieszka Karol, Michael O Schär, Michael Hottiger, Sumit Raniga, David Kenkel, Brigitte von Rechenberg, Matthias A Zumstein
BACKGROUND: Disturbed muscular architecture, atrophy, and fatty infiltration remain irreversible in chronic rotator cuff tears even after repair. Poly (adenosine 5'-diphosphate-ribose) polymerase 1 (PARP-1) is a key regulator of inflammation, apoptosis, muscle atrophy, muscle regeneration, and adipocyte development. We hypothesized that the absence of PARP-1 would lead to a reduction in damage to the muscle subsequent to combined tenotomy and neurectomy in a PARP-1 knockout (KO) mouse model...
January 25, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28123866/-64-cucl2-pet-ct-imaging-of-mouse-muscular-injury-induced-by-electroporation
#18
Fang Xie, Huawei Cai, Fangyu Peng
Skeletal muscle injury is common in body injuries suffered in sports and car accidents. Development of new tracers is significant for assessing muscular injury with positron emission tomography/computed tomography (PET/CT) and monitoring repair of muscle injury in response to treatment. Copper is required for wound healing and increased copper ions were detected in the soft tissue of wound in rodents and human. Based on the recent finding of increased (64)Cu uptake in the traumatic brain injury, this study aimed to explore use of (64)CuCl2 as a radiotracer for molecular imaging of muscular injury using PET/CT...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28099237/lower-limb-muscular-strength-balance-and-mobility-levels-in-adults-following-severe-thermal-burn-injuries
#19
Mohammed T A Omar, Amal M Abd El Baky, Anwar A Ebid
Severe burn injuries are associated with hypermetabolic response and increased catabolism. These lead to a vast loss of muscle mass and reduced muscle strength and function. Therefore, the aim of this study is to determine the impact of severe burn injuries on lower-limb muscular strength, balance, and mobility level in adults. Forty burned adults with burned TBSA (burned TBSA) ≥40% participated in this study. The peak torque and total work of quadriceps and knee flexors were calculated at 150°/sec using Biodex isokinetic dynamometer...
January 10, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28095141/an-old-problem-aging-and-skeletal-muscle-strain-injury
#20
Brent A Baker
: Clinical Scenario: Even though chronological aging is an inevitable phenomenological consequence occurring in every living organism, it is biological aging that may be the most significant factor challenging our quality of life. Development of functional limitations, resulting from improper maintenance and restoration of various organ systems, ultimately leads to reduced health and independence. Skeletal muscle is an organ system, that when challenged, is often injured in response to varying stimuli...
January 17, 2017: Journal of Sport Rehabilitation
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