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https://www.readbyqxmd.com/read/28315787/the-synergistic-influence-of-ischemic-time-and-surgical-precision-on-acute-kidney-injury-after-robotic-partial-nephrectomy
#1
Julien Dagenais, Matt Maurice, Pascal Mouracade, Onder Kara, Ryan Nelson, Ercan Malkoc, Jihad Kaouk
OBJECTIVES: To examine the dynamic and potentially synergistic influence of warm ischemia time (WIT) and excisional volume loss (EVL) on predicted rates of post-partial acute kidney injury (AKI) across a range of tumor complexities. To investigate whether these modifiable variables sensitize the kidney to the other's damaging influence. METHODS: We retrospectively reviewed 1,245 patients between 2006 and 2016 with bilateral kidneys and enhancing renal masses in our single-institution robotic partial nephrectomy (PN) database...
March 15, 2017: Urology
https://www.readbyqxmd.com/read/28315455/7-8-dihydroxyflavone-facilitates-the-action-exercise-to-restore-plasticity-and-functionality-implications-for-early-brain-trauma-recovery
#2
Gokul Krishna, Rahul Agrawal, Yumei Zhuang, Zhe Ying, Afshin Paydar, Neil G Harris, Luiz Fernando F Royes, Fernando Gomez-Pinilla
Metabolic dysfunction accompanying traumatic brain injury (TBI) severely impairs the ability of injured neurons to comply with functional demands. This limits the success of rehabilitative strategies by compromising brain plasticity and function, and highlights the need for early interventions to promote energy homeostasis. We sought to examine whether the TrkB agonist, 7,8-dihydroxyflavone (7,8-DHF) normalizes brain energy deficits and restablishes more normal patterns of functional connectivity, while enhancing the effects of exercise during post-TBI period...
March 14, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28284837/casr-and-calpain-contribute-to-the-ischemia-reperfusion-injury-of-spinal-cord
#3
Ji-Fu Sun, Hui-Lin Yang, Yong-Hui Huang, Qian Chen, Xing-Bing Cao, Da-Peng Li, Hao-Ming Shu, Run-Yu Jiang
Spinal cord ischemia reperfusion injury (SCIRI) can cause spinal cord dysfunction and even devastating paraplegia. Calcium-sensing receptor (CaSR) and calpain are two calcium related molecules which have been reported to be involved in the ischemia reperfusion injury of cardiomyocytes and the subsequent apoptosis. Here, we studied the expression of CaSR and calpain in spinal cord neurons and tissues, followed by the further investigation of the role of CaSR/calpain axis in the cellular apoptosis process during SCIRI...
March 8, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28284334/voluntary-wheel-running-differentially-affects-disease-outcomes-in-male-and-female-mice-with-experimental-autoimmune-encephalomyelitis
#4
Katherine A Mifflin, Emma Frieser, Curtis Benson, Glen Baker, Bradley J Kerr
Multiple sclerosis (MS) is an inflammatory neurodegenerative disease of the central nervous system. The primary symptoms of MS include the loss of sensory and motor function. Exercise has been shown to modulate disease parameters in experimental autoimmune encephalomyelitis (EAE), a mouse model of MS, by reducing immune cell infiltration and oxidative stress. However, these initial studies were carried out exclusively in female mice. The present study compared the effects of daily voluntary wheel running on several disease parameters in male and female mice with EAE...
April 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28283992/training-load-monitoring-in-team-sports-a-novel-framework-separating-physiological-and-biomechanical-load-adaptation-pathways
#5
Jos Vanrenterghem, Niels Jensby Nedergaard, Mark A Robinson, Barry Drust
There have been considerable advances in monitoring training load in running-based team sports in recent years. Novel technologies nowadays offer ample opportunities to continuously monitor the activities of a player. These activities lead to internal biochemical stresses on the various physiological subsystems; however, they also cause internal mechanical stresses on the various musculoskeletal tissues. Based on the amount and periodization of these stresses, the subsystems and tissues adapt. Therefore, by monitoring external loads, one hopes to estimate internal loads to predict adaptation, through understanding the load-adaptation pathways...
March 10, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28271169/-intraoperative-monitoring-of-the-facial-nerve-vestibular-schwannoma-surgery
#6
J Prell, C Strauss, S K Plontke, S Rampp
BACKGROUND: In vestibular schwannoma surgery, facial nerve injury with consecutive functional impairment is one of the most important complications. Intraoperative monitoring of facial nerve function has been developed in order to avoid this complication. OBJECTIVE: Which methods for intraoperative monitoring have been developed? Which methods are in use today and what can they achieve in modern vestibular schwannoma surgery? MATERIAL AND METHODS: This article provides an evaluation and summary of the literature, as well as a discussion of the methods and their ability to achieve the goals of intraoperative monitoring...
March 7, 2017: HNO
https://www.readbyqxmd.com/read/28269635/wearable-embroidered-muscle-activity-sensing-device-for-the-human-upper-leg
#7
R B Ribas Manero, A Shafti, B Michael, J Grewal, J Ll Ribas Fernandez, K Althoefer, M J Howard
Within the last decade, running has become one of the most popular physical activities in the world. Although the benefits of running are numerous, there is a risk of Running Related Injuries (RRIs) of the lower extremities. Electromyography (EMG) techniques have previously been used to study causes of RRIs, but the complexity of this technology limits its use to a laboratory setting. As running is primarily an outdoors activity, this lack of technology acts as a barrier to the study of RRIs in natural environments...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269460/monitoring-of-paces-and-gaits-using-binary-pir-sensors-with-rehabilitation-treadmill
#8
Jiang Lu, Ting Zhang, Qingquan Sun, Sanobar Kadiwal, Ishaq Unwala, Fei Hu
Recently, rehabilitation treadmills are designed for helping injured persons such as stroke patients and injury athletes in the process of physical therapy. By monitoring the changes of paces and gaits, one can estimate the progress of rehabilitation. At present, most devices that can estimate paces and gaits are wearable and/or expensive. This paper presents an inexpensive, non-intrusive wireless binary sensor system for pace estimation and lower-extreme gait recognition with low data throughput and high energy efficiency...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268204/an-empirical-analysis-of-run-off-road-injury-severity-crashes-involving-large-trucks
#9
Nabeel Saleem Saad Al-Bdairi, Salvador Hernandez
In recent years, there has been an increasing interest in understanding the contributory factors to run-off-road (ROR) crashes in the US, especially those where large trucks are involved. Although there have been several efforts to understand large-truck crashes, the relationship between crash factors, crash severity, and ROR crashes is not clearly understood. The intent of this research is to develop statistical models that provide additional insight into the effects that various contributory factors related to the person (driver), vehicle, crash, roadway, and environment have on ROR injury severity...
March 4, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28265245/passion-and-pacing-in-endurance-performance
#10
Lieke Schiphof-Godart, Florentina J Hettinga
Endurance sports are booming, with sports passionates of varying skills and expertise battering city streets and back roads on their weekly or daily exercise rounds. The investments required for performing in endurance exercise are nevertheless considerable, and passion for their sport might explain the efforts endurance athletes are willing to make. Passion may be defined as a strong motivational force and as such might be related to the neurophysiological basis underlying the drive to exercise. A complex relationship between the brain and other systems is responsible for athletes' exercise behavior and thus performance in sports...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28263670/proximal-neuromuscular-control-protects-against-hamstring-injuries-in-male-soccer-players
#11
Joke Schuermans, Lieven Danneels, Damien Van Tiggelen, Tanneke Palmans, Erik Witvrouw
BACKGROUND: With their unremittingly high incidence rate and detrimental functional repercussions, hamstring injuries remain a substantial problem in male soccer. Proximal neuromuscular control ("core stability") is considered to be of key importance in primary and secondary hamstring injury prevention, although scientific evidence and insights on the exact nature of the core-hamstring association are nonexistent at present. HYPOTHESIS: The muscle activation pattern throughout the running cycle would not differ between participants based on injury occurrence during follow-up...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28254534/lower-limb-mechanical-asymmetry-during-repeated-treadmill-sprints
#12
Olivier Girard, Franck Brocherie, Jean-Benoit Morin, Grégoire P Millet
Stride mechanical imbalances between the lower limbs may be detrimental to performance and/or increase injury risks. This study describes the time course and magnitude of asymmetries in running mechanical variables during repeated treadmill sprints and examines whether inter-limb differences in sprinting mechanics increase with fatigue. Thirteen non-injured male athletes performed five 5-s sprints with 25-s recovery on an instrumented treadmill, allowing the continuous (step-by-step) measurement of running kinetics/kinematics and spring-mass characteristics calculation...
February 27, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28253059/are-injuries-more-common-with-crossfit-training-than-other-forms-of-exercise
#13
Chelsey Klimek, Christopher Ashbeck, Alexander J Brook, Chris Durall
Clinical Scenario: CrossFit is a form of exercise that incorporates rapid and successive high-intensity, ballistic movements. As CrossFit becomes an increasingly popular fitness option, it is important to determine how rates of injury compare to more traditional forms of exercise. This review was conducted to ascertain the incidence of injury with CrossFit relative to other forms of exercise. Focused Clinical Question: Are injuries more common with CrossFit training than other forms of exercise? Summary of Key Findings The literature was searched for studies that compared injury rates among individuals who participated in CrossFit fitness programs to participants in other exercise programs The search initially yielded >100 results which was narrowed down to three level 2b retrospective cohort studies that was deemed to have met inclusion/exclusion criteria In all three reviewed studies, the reported incidences of injuries associated with CrossFit training programs were comparable or lower than rates of injury in Olympic weightlifting, distance running, track and field, rugby, or gymnastics...
March 2, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28253053/kinematic-gait-patterns-in-competitive-and-recreational-runners
#14
Christian A Clermont, Sean T Osis, Angkoon Phinyomark, Reed Ferber
Certain homogeneous running subgroups demonstrate distinct kinematic patterns in running; however, the running mechanics of competitive and recreational runners are not well understood. Therefore, the purpose of this study was to determine whether we could separate and classify competitive and recreational runners according to gait kinematics using multivariate analyses and a machine learning approach. Participants were allocated to the 'competitive' (n=20) or 'recreational' group (n=15) based on age, gender, and recent race performance...
March 2, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28253034/playing-experience-and-position-influence-injury-risk-among-ncaa-division-i-collegiate-footballers
#15
Robert McCunn, Hugh H K Fullagar, Sean Williams, Travis J Halseth, John A Sampson, Andrew Murray
PURPOSE: American football is widely played by collegiate student-athletes throughout the United States; however, the associated injury risk is greater than in other team sports. Numerous factors likely contribute to this risk yet research identifying these risk factors is limited. The present study sought to explore the relationship between playing experience and position on injury risk within NCAA Division I collegiate footballers. METHODS: Seventy-six male collegiate student athletes within the American football program of an NCAA Division I university participated...
March 2, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28245273/influence-of-custom-made-and-prefabricated-insoles-before-and-after-an-intense-run
#16
Angel Gabriel Lucas-Cuevas, Andrés Camacho-García, Raúl Llinares, Jose Ignacio Priego Quesada, Salvador Llana-Belloch, Pedro Pérez-Soriano
Each time the foot contacts the ground during running there is a rapid deceleration that results in a shock wave that is transmitted from the foot to the head. The fatigue of the musculoskeletal system during running may decrease the ability of the body to absorb those shock waves and increase the risk of injury. Insoles are commonly prescribed to prevent injuries, and both custom-made and prefabricated insoles have been observed to reduce shock accelerations during running. However, no study to date has included a direct comparison of their behaviour measured over the same group of athletes, and therefore great controversy still exists regarding their effectiveness in reducing impact loading during running...
2017: PloS One
https://www.readbyqxmd.com/read/28244515/a-microfluidic-perfusion-approach-for-on-chip-characterization-of-the-transport-properties-of-human-oocytes
#17
Gang Zhao, Zhiguo Zhang, Yuntian Zhang, Zhongrong Chen, Dan Niu, Yunxia Cao, Xiaoming He
Accurate characterization of the cell membrane transport properties of human oocytes is of great significance to reproductive pharmacology, fertility preservation, and assisted reproduction. However, the commonly used manual method for quantifying the transport properties is associated with uncontrolled operator-to-operator and run-to-run variability. Here, we report a novel sandwich structured microfluidic device that can be readily fabricated for characterizing oocyte membrane transport properties. Owing to its capacity for excellent control of both solution replacement and temperature in the microchannel, the temperature-dependent permeability of the oocyte membrane can be precisely characterized...
February 28, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28240709/changes-in-vertical-and-joint-stiffness-in-runners-with-advancing-age
#18
Douglas W Powell, D S Blaise Williams
BACKGROUND: Age-related changes in the neuromuscular system underlie reduced performance and injury, but may be mitigated through regular physical activity. It was hypothesized that older (OLD) compared to young (YOUNG) adults would exhibit greater vertical and joint stiffness when running at 3.35 m/s. METHODS: Nine YOUNG and ten OLD runners performed over ground running trials while three-dimensional biomechanics were recorded. Ankle and knee joint angles, moments and stiffness values were compared between YOUNG & OLD...
February 23, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28237655/a-prospective-comparison-of-lower-extremity-kinematics-and-kinetics-between-injured-and-non-injured-collegiate-cross-country-runners
#19
Robert I Dudley, Derek N Pamukoff, Scott K Lynn, Robert D Kersey, Guillermo J Noffal
Collegiate cross country runners are at risk for running related injuries (RRI) due to high training volume and the potential for aberrant lower extremity biomechanics. However, there is a need for prospective research to determine biomechanical risk factors for RRI. The purpose of this study was to prospectively compare ankle, knee, and hip kinematics and kinetics and ground reaction force characteristics between injured and non-injured cross country runners over a 14-week season. Biomechanical running analyses were conducted on 31 collegiate-cross country runners using a 3-dimensional motion capture system and force plate prior to the start of the season...
February 23, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28236094/-diseases-and-overuse-injuries-of-the-lower-extremities-in-long-distance-runners
#20
REVIEW
M Tschopp, F Brunner
Running is one of the most popular sports worldwide, with running events attracting hundreds of thousands of runners of all age groups. Running is an effective way to improve health but is also associated with a high risk of injuries. Up to 50% of regular runners report having more than one injury each year. Some injuries are caused by an accident but most are caused by overuse. The most frequent diagnoses are patellofemoral pain syndrome, tibial stress syndrome (shin splint), Achilles tendinopathy, iliotibial band friction syndrome (runner's knee), plantar fasciitis and stress fractures of the metatarsals and tibia...
February 24, 2017: Zeitschrift Für Rheumatologie
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