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https://www.readbyqxmd.com/read/28926748/association-between-infection-burden-and-adult-height
#1
Dawson W Hedges, Andrew N Berrett, Lance D Erickson, Bruce L Brown, Shawn D Gale
Although highly heritable, adult height is also associated with numerous environmental factors, including exposure to infection. Particularly in developing regions of the world, infection burden appears to slow growth during childhood. Using a large database representative of the US population, we examined associations between adult height and leg length and an infection-burden index based on past exposure to Toxocara species, Toxoplasmosis gondii, cytomegalovirus, hepatitis A, hepatitis B, hepatitis C, herpes simplex virus 1, and herpes simplex virus 2...
September 2, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28916885/geometric-analysis-and-clinical-outcome-of-two-cemented-stems-for-primary-total-hip-replacement-with-and-without-modular-necks
#2
Marcel Haversath, Christine Wendelborn, Marcus Jäger, Boris Schmidt, Wojciech Kowalczyk, Stefan Landgraeber
INTRODUCTION: Restoration of the physiological biomechanical principles of the hip is crucial in total hip replacement. The aim of this study was to compare an arthroplasty system with different offset options (a: Exeter(®)) with a dual-modular stem (b: Profemur Xm(®)). MATERIALS AND METHODS: A local and an inertial coordinate system were used to assist the description of the components' assembly in the prosthesis. A resection line of the femoral head in standard position was added to the arthroplasties and geometric parameters were measured...
September 15, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28905509/de-novo-setd5-loss-of-function-variant-as-a-cause-for-intellectual-disability-in-a-10-year-old-boy-with-an-aberrant-blind-ending-bronchus
#3
Claire Green, Joshua Willoughby, Meena Balasubramanian
Although rare, 3p microdeletion cases have been well described in the clinical literature. The clinical phenotype includes; intellectual disability (ID), growth retardation, facial dysmorphism, and cardiac malformations. Advances in chromosome microarray (CMA) testing narrowed the 3p25 critical region to a 124 kb region, and recent Whole Exome Sequencing (WES) studies have suggested that the SETD5 gene contributes significantly to the 3p25 phenotype. Loss-of-Function (LoF) variants in SETD5 are now considered a likely cause of ID...
September 14, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28904147/long-legged-bees-make-adaptive-leaps-linking-adaptation-to-coevolution-in-a-plant-pollinator-network
#4
Anton Pauw, Belinda Kahnt, Michael Kuhlmann, Denis Michez, Graham A Montgomery, Elizabeth Murray, Bryan N Danforth
Adaptation is evolution in response to natural selection. Hence, an adaptation is expected to originate simultaneously with the acquisition of a particular selective environment. Here we test whether long legs evolve in oil-collecting Rediviva bees when they come under selection by long-spurred, oil-secreting flowers. To quantify the selective environment, we drew a large network of the interactions between Rediviva species and oil-secreting plant species. The selective environment of each bee species was summarized as the average spur length of the interacting plant species weighted by interaction frequency...
September 13, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28887022/additive-influence-of-hip-offset-and-leg-length-reconstruction-on-postoperative-improvement-in-clinical-outcome-after-total-hip-arthroplasty
#5
Moritz M Innmann, Michael W Maier, Marcus R Streit, George Grammatopoulos, Thomas Bruckner, Tobias Gotterbarm, Christian Merle
BACKGROUND: There is a lack of prospective studies investigating the additive effect of both acetabular and femoral reconstruction parameters on the functional outcome following total hip arthroplasty (THA). METHODS: The aim of this prospective cohort study was to determine the combined influence of hip geometry reconstruction and component positioning on the clinical outcome following primary THA for unilateral osteoarthritis. We prospectively assessed the clinical outcome and radiographic parameters for hip geometry reconstruction, component position, and orientation using validated measurements for the operated hip compared to the contralateral native hip in a consecutive series of 113 patients with primary unilateral cementless THA...
August 12, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28882379/reliable-anatomical-landmarks-for-minimizing-leg-length-discrepancy-during-hip-arthroplasty-using-the-lateral-transgluteal-approach-for-femoral-neck-fracture
#6
Jeung Il Kim, Nam Hoon Moon, Won Chul Shin, Kuen Tak Suh, Jae Yoon Jeong
BACKGROUND: The purpose of this study was to describe our experience of a preoperative templating technique, and to investigate the most reliable anatomical reference to minimize leg length discrepancy (LLD) during hip arthroplasty using the lateral transgluteal approach for femoral neck fractures. We hypothesized that the medial fracture tip and greater trochanter would be viable alternative anatomical References METHODS: A total of 156 hip arthroplasty cases were enrolled in the present study (103 women, 114 hemiarthroplasties, 42 total hip arthroplasties)...
September 1, 2017: Injury
https://www.readbyqxmd.com/read/28865387/exploring-the-relationship-between-stride-stature-and-hand-size-for-forensic-assessment
#7
Richard Guest, Oscar Miguel-Hurtado, Sarah Stevenage, Sue Black
Forensic evidence often relies on a combination of accurately recorded measurements, estimated measurements from landmark data such as a subject's stature given a known measurement within an image, and inferred data. In this study a novel dataset is used to explore linkages between hand measurements, stature, leg length and stride. These three measurements replicate the type of evidence found in surveillance videos with stride being extracted from an automated gait analysis system. Through correlations and regression modelling, it is possible to generate accurate predictions of stature from hand size, leg length and stride length (and vice versa), and to predict leg and stride length from hand size with, or without, stature as an intermediary variable...
August 26, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28861192/comparison-of-outcomes-of-total-hip-arthroplasty-between-patients-with-ankylosing-spondylitis-and-avascular-necrosis-of-the-femoral-head
#8
Sun-Ho Lee, Gun-Woo Lee, Young-Jun Seol, Kyung-Soon Park, Taek-Rim Yoon
BACKGROUND: The objective of this study was to compare clinical and radiological outcomes of total hip arthroplasty (THA) between ankylosing spondylitis (AS) of the hip joint and avascular necrosis (AVN) of the femoral head. METHODS: Thirty patients (30 hips) underwent cementless THA for AS between 2003 and 2012. They were compared to 30 patients (30 hips) who underwent the same procedure for AVN of the femoral head. Each group was matched for age and gender, and both groups had similar preoperative demographic characteristics...
September 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/28843930/gait-and-its-components-in-typically-developing-preschoolers
#9
Evi Verbecque, Luc Vereeck, Paul Van de Heyning, Ann Hallemans
OBJECTIVES: To determine whether key spatio-temporal components of gait can be identified in children who are preschoolers. Subsequently the obtained components were correlated to results of functional balance tests to determine which of them are related to balance control. METHODS: Thirty-three typically developing children performed gait on treadmill at three speeds (range 2-4.5km/h), the Pediatric Balance Scale (PBS) and the Timed Up and Go test (TUG). Principal component analysis (PCA) with varimax rotation was performed to detect relations between means and variability of step time, -length and -width, walking speed, age, BMI and leg length...
August 12, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28840156/clinical-outcome-reporting-in-youth-acl-literature-is-widely-variable
#10
REVIEW
Christopher M Brusalis, Nikita Lakomkin, Joash R Suryavanshi, Aristides I Cruz, Daniel W Green, Kristofer J Jones, Peter D Fabricant
BACKGROUND: Advances in anterior cruciate ligament (ACL) reconstruction procedures in pediatric and adolescent patients have resulted in an increase in recent clinical studies on this topic. However, the consistency with which outcome measures are reported in this demographic is unknown. PURPOSE: To document outcome reporting patterns of youth ACL reconstruction studies in high-impact journals. STUDY DESIGN: Systematic review; Level of evidence, 4...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28832938/energetic-cost-of-walking-in-fossil-hominins
#11
M Vidal-Cordasco, A Mateos, G Zorrilla-Revilla, O Prado-Nóvoa, J Rodríguez
OBJECTIVE: Many biomechanical studies consistently show that a broader pelvis increases the reaction forces and bending moments across the femoral shaft, increasing the energetic costs of unloaded locomotion. However, a biomechanical model does not provide the real amount of metabolic energy expended in walking. The aim of this study is to test the influence of pelvis breadth on locomotion cost and to evaluate the locomotion efficiency of extinct Pleistocene hominins. MATERIAL AND METHODS: The current study measures in vivo the influence of pelvis width on the caloric cost of locomotion, integrating anthropometry, body composition and indirect calorimetry protocols in a sample of 46 subjects of both sexes...
August 19, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28827057/ilizarov-hip-reconstruction-osteotomy-a-review
#12
Masood Umer, Talal Aqueel Quadri, Rizwan Haroon Rashid
Hip joint instability can be secondary to congenital hip pathologies like developmental dysplasia (DDH) or acquired such as sequel of infective or neoplastic process. An unstable hip is usually associated with loss of bone from the proximal femur, shortening, abnormal gait, and pain. Many authors have suggested proximal femoral valgus osteotomy for the treatment of unstable hip joints. Ilizarov modified this technique and performed a double-level osteotomy. In addition to proximal femoral valgus extension osteotomy, he introduced a distal femoral varus osteotomy which would lead to limb lengthening and correction of mechanical axis of the leg...
August 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28793888/does-structural-leg-length-discrepancy-affect-postural-control-preliminary-study
#13
Małgorzata Eliks, Wioleta Ostiak-Tomaszewska, Przemysław Lisiński, Paweł Koczewski
BACKGROUND: Leg-length inequality results in an altered position of the spine and pelvis. Previous studies on the influence of leg asymmetry on postural control have been inconclusive. The purpose of this paper was to investigate the effect of structural leg-length discrepancy (LLD) on the control of posture. METHODS: We studied 38 individuals (19 patients with structural LLD, 19 healthy subjects). The examination included measurement of the length of the lower limbs and weight distribution as well as a static posturography...
August 9, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28793284/growth-hormone-therapy-in-children-with-kabuki-syndrome-1-year-treatment-results
#14
Dina A Schott, Willem J M Gerver, Constance T R M Stumpel
BACKGROUND/AIMS: Kabuki syndrome (KS) is a rare genetic malformation syndrome, resulting in characteristic features such as short stature. We investigate whether growth hormone (GH) treatment increases linear height and influences body proportions in KS children. METHODS: In this prospective study, 18 genetically confirmed prepubertal KS children (9 females and 9 males) aged from 3.8 to 10.1 years (mean 6.8 ± 2.1 years) were treated with recombinant human GH (rhGH) for 1 year...
August 9, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28757446/playing-with-extremes-origins-and-evolution-of-exaggerated-female-forelegs-in-south-african-rediviva-bees
#15
Belinda Kahnt, Graham A Montgomery, Elizabeth Murray, Michael Kuhlmann, Anton Pauw, Denis Michez, Robert J Paxton, Bryan N Danforth
Despite close ecological interactions between plants and their pollinators, only some highly specialised pollinators adapt to a specific host plant trait by evolving a bizarre morphology. Here we investigated the evolution of extremely elongated forelegs in females of the South African bee genus Rediviva (Hymenoptera: Melittidae), in which long forelegs are hypothesised to be an adaptation for collecting oils from the extended spurs of their Diascia host flowers. We first reconstructed the phylogeny of the genus Rediviva using seven genes and inferred an origin of Rediviva at around 29MYA (95% HPD=19...
July 27, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28756566/pten-hamartoma-of-the-soft-tissue-the-initial-manifestation-of-an-underlying-pten-hamartoma-tumor-syndrome-in-a-4-year-old-female
#16
Charles B Chism, Lindsay Crawford, Amanda Tchakarov, Alyaa Al-Ibraheemi, Nicholas M Beckmann
A 4-year-old female was referred to pediatric orthopedic surgery for left leg pain and limping for 3 months following a motor vehicle collision. Recently, the patient's mother had noted left knee swelling and dragging of the left leg when walking. Past medical history was significant for hip dysplasia with slight leg length discrepancy. The patient was otherwise healthy. Physical examination was remarkable for left pre-patellar soft tissue fullness with normal range of motion. There was no warmth or tenderness...
July 29, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28752819/computer-assisted-navigation-in-total-knee-and-hip-arthroplasty
#17
Kamal Deep, Shivakumar Shankar, Ashish Mahendra
INTRODUCTION: Computer assisted surgery was pioneered in early 1990s. The first computer assisted surgery (CAS) total knee replacement with an imageless system was carried out in 1997. In the past 25 years, CAS has progressed from experimental in vitro studies to established in vivo surgical procedures. METHODS: A comprehensive body of evidence establishing the advantages of computer assisted surgery in knee and hip arthroplasty is available. Established benefits have been demonstrated including its role as an excellent research tool...
2017: SICOT-J
https://www.readbyqxmd.com/read/28750263/biomechanical-differences-between-cases-with-chronic-exertional-compartment-syndrome-and-asymptomatic-controls-during-walking-and-marching-gait
#18
Andrew Roberts, David Roscoe, David Hulse, Alexander N Bennett, Sharon Dixon
Chronic exertional compartment syndrome is a significant problem in military populations that may be caused by specific military activities. This study aimed to investigate the kinematic and kinetic differences in military cases with chronic exertional compartment syndrome and asymptomatic controls. 20 males with symptoms of chronic exertional compartment syndrome of the anterior compartment and 20 asymptomatic controls were studied. Three-dimensional lower limb kinematics and kinetics were compared during walking and marching...
July 18, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28748830/a-neural-network-with-central-pattern-generators-entrained-by-sensory-feedback-controls-walking-of-a-bipedal-model
#19
Wei Li, Nicholas Stephen Szczecinski, Roger D Quinn
A neuromechanical simulation of a planar, bipedal walking robot has been developed. It is constructed as a simplified, planar musculoskeletal model of the biomechanics of the human lower body. The controller consists of a dynamic neural network with central pattern generators (CPGs) entrained by force and movement sensory feedback to generate appropriate muscle forces for walking. The CPG model is a two-level architecture, which consists of separate rhythm generator (RG) and pattern formation (PF) networks...
July 27, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28741029/subtrochanteric-femoral-shortening-osteotomy-combined-with-cementless-total-hip-replacement-for-crowe-type-iv-developmental-dysplasia-a-retrospective-study
#20
Giuseppe Rollo, Giuseppe Solarino, Giovanni Vicenti, Girolamo Picca, Massimiliano Carrozzo, Biagio Moretti
BACKGROUND: Total hip replacement for high dislocation of the hip presents some difficulties, considering patients' young ages, the abnormal hip anatomy and the high rate of complications. In this study, we present our experience in terms of clinical and radiological results in the treatment of Crowe type IV hips with subtrochanteric femoral shortening osteotomy and cementless total hip replacement. MATERIALS AND METHODS: We retrospectively reviewed 15 patients with Crowe type IV hip dysplasia (two bilateral cases for a total of 17 hips) treated with cementless total hip replacement associated with shortening subtrochanteric osteotomies (nine transversal and eight Z-shape osteotomies) between March 2000 to February 2006...
July 24, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
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