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https://www.readbyqxmd.com/read/29774305/multi-slice-mri-reveals-heterogeneity-in-disease-distribution-along-the-length-of-muscle-in-duchenne-muscular-dystrophy
#1
Stephen M Chrzanowski, Celine Baligand, Rebecca J Willcocks, Jasjit Deol, Ilona Schmalfuss, Donovan J Lott, Michael J Daniels, Claudia Senesac, Glenn A Walter, Krista Vandenborne
Background: Duchenne muscular dystrophy (DMD) causes progressive pathologic changes to muscle secondary to a cascade of inflammation, lipid deposition, and fibrosis. Clinically, this manifests as progressive weakness, functional loss, and premature mortality. Though insult to whole muscle groups is well established, less is known about the relationship between intramuscular pathology and function. Objective: Differences of intramuscular heterogeneity across muscle length were assessed using an ordinal MRI grading scale in lower leg muscles of boys with DMD and correlated to patient's functional status...
September 2017: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/29761618/robot-assisted-total-hip-arthroplasty-clinical-outcomes-and-complication-rate
#2
Itay Perets, John P Walsh, Mary R Close, Brian H Mu, Leslie C Yuen, Benjamin G Domb
BACKGROUND: The purpose of this study was to report minimum 2-year outcomes and complications for robotic-arm-assisted total hip arthroplasty (THA). METHODS: Data were prospectively collected and retrospectively reviewed between June 2011 and April 2014. Inclusion criteria were primary robotic-arm-assisted THAs treating idiopathic osteoarthritis with ≥ 2-year follow-up. Demographics, operating time, complications, 2-year outcome scores and satisfaction, and subsequent surgeries were recorded...
May 15, 2018: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29754479/pre-operative-ultrasonographic-prediction-of-hamstring-autograft-size-for-anterior-cruciate-ligament-reconstruction-surgery
#3
M A Mohd Asihin, M Y Bajuri, J Ahmad, S F Syed Kamaruddin
Objectives: To evaluate the feasibility of ultrasonographic examination in predicting 4-strand semitendinosus and gracilis tendon (4S-STG) autograft size preoperatively in anterior cruciate ligament reconstruction and to evaluate the use of anthropometric measurement to predict the 4-strand semitendinosus and gracilis tendons (4S-STG) autograft size pre-operatively in anterior cruciate ligament reconstruction. Method: Twenty-seven patients were included in this study conducted from 1st January to 31st December 2013...
March 31, 2018: Ceylon Medical Journal
https://www.readbyqxmd.com/read/29743109/muscle-and-tendon-morphology-alterations-in-children-and-adolescents-with-mild-forms-of-spastic-cerebral-palsy
#4
Annika Kruse, Christian Schranz, Markus Tilp, Martin Svehlik
BACKGROUND: Early detection of changes at the muscular level before a contracture develops is important to gain knowledge about the development of deformities in individuals with spasticity. However, little information is available about muscle morphology in children with spastic diplegic cerebral palsy (CP) without contracture or equinus gait. Therefore, the aim of this study was to compare the gastrocnemius medialis (GM) and Achilles tendon architecture of children and adolescents with spastic CP without contracture or equinus gait to that of typically developing (TD) children...
May 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29729934/is-direct-anterior-approach-a-credible-option-for-severely-obese-patients-undergoing-total-hip-arthroplasty-a-matched-control-retrospective-clinical-study
#5
Alexander Antoniadis, Dimitris Dimitriou, Andreas Flury, Gregor Wiedmer, Julian Hasler, Naeder Helmy
BACKGROUND: Severely obese patients present a significant challenge for arthroplasty surgeons because of their body habitus. Up to date, there is no clear consensus on the safety of the direct anterior approach (DAA) in obese patients undergoing total hip arthroplasty. Therefore, the purpose of the present study was to determine whether DAA is a credible option in severely obese regarding complication rates, clinical outcomes, and component positioning. METHODS: Obese patients with a body mass index ≥ 35 kg/m2 (n = 129) who received total hip arthroplasty with DAA in our institution were matched for gender and age with nonobese patients with body mass index ≤ 25 kg/m2 (n = 125)...
April 11, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29726316/correlation-of-radiological-and-clinical-measurement-of-genu-valgum-in-children
#6
Nina Hardgrib, Martin Gottliebsen, Ole Rahbek, Michel Bach Hellfritzsch, Bjarne Møller-Madsen
INTRODUCTION: Genu valgus is a condition characterised by a lateral shift of the knee's mechanical axis. The deformity can be characterised using clinical examinations and long hip-knee-ankle (HKA) angles, but it is unclear how these investigations correlate with each other. Our aim was to examine the correlation between clinical and radiographic measurements of the lower extremities in children. METHODS: A total of 49 children between 5.9 and 16.7 years of age who had been referred with genu valgum deformity were included...
May 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29721550/evaluation-of-functional-and-structural-leg-length-discrepancy-in-patients-with-adolescent-idiopathic-scoliosis-using-the-eos-imaging-system-a-prospective-comparative-study
#7
Tatsuhiro Sekiya, Yoichi Aota, Katsutaka Yamada, Kanichiro Kaneko, Manabu Ide, Tomoyuki Saito
Background: To our knowledge, no studies have reported the exact structural leg length discrepancies (LLDs) in patients with adolescent idiopathic scoliosis (AIS). Therefore, this study aimed to evaluate the differences between functional and structural LLDs and to examine the correlations between LLDs and spinopelvic parameters in patients with AIS using an EOS imaging system, which permits the three-dimensional reconstruction of spinal and lower-limb bony structures. Methods: Eighty-two consecutive patients with AIS underwent whole-body EOS radiography in a standing position between August 2014 and March 2016...
2018: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/29720948/the-oxygen-consumption-and-metabolic-cost-of-walking-and-running-in-adults-with-achondroplasia
#8
David T Sims, Gladys L Onambélé-Pearson, Adrian Burden, Carl Payton, Christopher I Morse
The disproportionate body mass and leg length of Achondroplasic individuals may affect their net oxygen consumption ([Formula: see text]O2 ) and metabolic cost (C) when walking at running compared to those of average stature (controls). The aim of this study was to measure submaximal [Formula: see text]O2 and C during a range of set walking speeds (SWS; 0.56 - 1.94 m⋅s-1 , increment 0.28 m⋅s-1 ), set running speeds (SRS; 1.67 - 3.33 m⋅s-1 , increment 0.28 m⋅s-1 ) and a self-selected walking speed (SSW)...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29707059/posteromedial-bowing-of-the-tibia-a-benign-condition-or-a-case-for-limb-reconstruction
#9
J Wright, R A Hill, D M Eastwood, A Hashemi-Nejad, P Calder, S Tennant
Purpose: To review the initial deformity and subsequent remodelling in posteromedial bowing of the tibia and the outcome of limb reconstruction in this condition. Patients and Methods: In all, 38 patients with posteromedial bowing of the tibia presenting between 2000 and 2016 were identified. Mean follow-up from presentation was 78 months. A total of 17 patients underwent lengthening and deformity correction surgery, whilst three further patients are awaiting lengthening and deformity correction procedures...
April 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29705520/developmental-changes-in-spatial-margin-of-stability-in-typically-developing-children-relate-to-the-mechanics-of-gait
#10
Ann Hallemans, Evi Verbecque, Raphael Dumas, Laurence Cheze, Angèle Van Hamme, Thomas Robert
BACKGROUND: Immature balance control is considered an important rate limiter for maturation of gait. The spatial margin of stability (MoS) is a biomechanical measure of dynamic balance control that might provide insights into balance control strategies used by children during the developmental course of gait. RESEARCH HYPOTHESIS: We hypothesize there will be an age-dependent decrease in MoS in children with typical development. To understand the mechanics, relations between MoS and spatio-temporal parameters of gait are investigated...
April 18, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29702369/barefoot-plantar-pressure-measurement-in-chronic-exertional-compartment-syndrome
#11
D Roscoe, A J Roberts, D Hulse, A Shaheen, M P Hughes, A Bennett
BACKGROUND: Patients with Chronic Exertional Compartment Syndrome (CECS) have exercise-limiting pain that subsides at rest. Diagnosis is confirmed by intramuscular compartment pressure (IMCP) measurement. Accompanying CECS, subjective changes to gait (foot slap) are frequently reported by patients. This has not previously been investigated. The aim of this study was to investigate differences in barefoot plantar pressure (BFPP) between CECS cases and asymptomatic controls prior to the onset of painful symptoms...
April 9, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29701087/the-positive-predictive-value-of-asymmetrical-skin-creases-in-the-diagnosis-of-pathological-developmental-dysplasia-of-the-hip
#12
M J Anderton, G R Hastie, R W Paton
Aims The aim of this study was to identify the association between asymmetrical skin creases of the thigh, buttock or inguinal region and pathological developmental dysplasia of the hip (DDH). Patients and Methods Between 1 January 1996 and 31 December 2016, all patients referred to our unit from primary or secondary care with risk factors for DDH were assessed in a "one stop" clinic. All had clinical and sonographic assessment by the senior author (RWP) with the results being recorded prospectively...
May 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29700988/leg-length-inequality-and-hip-osteoarthritis-in-the-multicenter-osteoarthritis-study-and-the-osteoarthritis-initiative
#13
Chan Kim, Michael Nevitt, Ali Guermazi, Jingbo Niu, Margaret Clancy, Irina Tolstykh, Pia M Jungmann, Nancy E Lane, Neil A Segal, Wiiliam F Harvey, Cora E Lewis, David T Felson
OBJECTIVE: Studies suggest that persons with a 2 cm shorter limb have an increased risk of knee osteoarthritis (OA) in that limb. We examined whether leg length inequality (LLI) confers an increased risk of hip OA. METHODS: Using long limb radiographs from MOST and the Osteoarthritis Initiative, we measured LLI and scored hip radiographs which were obtained at baseline and 3-5 year follow-up. We examined the association of >1 cm LLI and >2 cm of LLI with radiographic hip OA cross-sectionally and longitudinally, assessing risk in shorter limbs and longer limbs compared with limbs with no LLI...
April 26, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29695910/total-hip-arthroplasty-following-arthrodesis-a-single-center-experience-of-17-patients
#14
Murat Çalbıyık
Purpose: We aimed to present our experience with total hip arthroplasty in patients with previous hip arthrodesis. Patients and methods: This was a retrospective study, in which clinical and radiological outcomes of total hip arthroplasty performed in 17 patients (mean age 54.2±8.5 years; age range 33-68 years; female to male ratio 10/7) with previous arthrodesis in our clinic between 2001 and 2014 were reviewed. Patients were followed up for 6.7±2.8 years (range 3-12 years) after the operation and evaluated for ipsilateral knee pain, range of motion, walking capacity, and leg-length discrepancy...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29674772/total-hip-arthroplasty-for-patients-with-residual-poliomyelitis-at-a-mean-eight-years-of-follow-up
#15
Mayumi Sonekatsu, Motoki Sonohata, Masaru Kitajima, Shunsuke Kawano, Masaaki Mawatari
In patients with poliomyelitis, degenerative arthritis of the hip may be encountered in the paralytic or normal contralateral limb because of leg length discrepancy, pelvic obliquity, or severe deformities of the affected hip. Although total hip arthroplasty (THA) is one of the most common orthopedic procedures, there are few reports of THA in adult patients with residual poliomyelitis. From March 2001 to January 2011, 5 patients with residual poliomyelitis (6 hips) underwent THA using uncemented implants at our hospital...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29672748/biopsychosocial-profiles-and-functional-correlates-in-older-adults-with-chronic-low-back-pain-a-preliminary-study
#16
Debra K Weiner, Angela Gentili, Katherine Coffey-Vega, Natalia Morone, Michelle Rossi, Subashan Perera
Objective: To describe key peripheral and central nervous system (CNS) conditions in a group of older adults with chronic low back pain (CLBP) and their association with pain severity and self-reported and performance-based physical function. Design: Cross-sectional. Setting: Outpatient VA clinics. Subjects: Forty-seven community-dwelling veterans with CLBP (age 68.0 ± 6.5 years, range = 60-88 years, 12.8% female, 66% white) participated...
April 16, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29669167/scoliosis-in-fibrous-dysplasia-mccune-albright-syndrome-factors-associated-with-curve-progression-and-effects-of-bisphosphonates
#17
Jason A Berglund, Sri Harsha Tella, Kaitlyn F Tuthill, Lauren Kim, Lori C Guthrie, Scott M Paul, Robert Stanton, Michael T Collins, Alison M Boyce
BACKGROUND: Scoliosis is a complication of fibrous dysplasia/McCune-Albright syndrome (FD/MAS), however risk factors and long-term outcomes are unknown. Bisphosphonates are commonly used; however, it is unknown whether their use decrease the risk of progressive scoliosis. METHODS: Clinical data from the NIH cohort study was reviewed. Cobb angles were measured, and variables associated with scoliosis progression were identified. RESULTS: Of 138 subjects with available radiographs, 84 (61%) had scoliosis, including 55 (65%) classified as mild (Cobb angle >10 to ≤30°), 11 (13%) as moderate (>30 to ≤45°), and 18 (22%) as severe (>45°)...
April 18, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29666734/open-reduction-and-internal-fixation-of-a-proximal-femoral-shaft-fracture-in-a-patient-with-bilateral-congenital-hip-disease
#18
Stefania Kanata, Antonios Anastasiadis
We present a rare case of a femoral shaft fracture in a 74-year-old woman with a preexisting untreated bilateral congenital hip dislocation and with concomitant leg length discrepancy. Because of the marked deformity of the upper femur, a derivative of the congenital hip disease, an open reduction and internal fixation was performed, with the use of an anatomic femur plate originally designed for the treatment of periprosthetic fractures. The patient was treated successfully and returned to her previous status of activity...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29661526/a-retrieval-analysis-of-impingement-in-dual-mobility-liners
#19
Trevor P Scott, Lydia Weitzler, Anthony Salvatore, Timothy M Wright, Geoffrey H Westrich
BACKGROUND: Implant-related impingement is likely a major causative factor of total hip arthroplasty (THA) instability. Dual-mobility (DM) cups can theoretically improve stability in THA, but impingement rates with DM cups are not well studied. We examined retrieved DM THA liners to determine if less evidence existed for prosthetic impingement between the neck and the polyethylene liner than historical studies from our institution on fixed-bearing THAs. METHODS: DM components from 93 THAs were identified from 164 THAs whose DM components were revised between 2008 and 2015 through our institutional review board-approved implant retrieval program...
March 16, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29657461/growth-modulation-for-coronal-deformity-correction-by-using-eight-plates-systematic-review
#20
REVIEW
Sanjay Kumar, S V Sonanis
Introduction: Coronal deformities are commonly encountered in paediatric orthopaedics and surgical treatment is indicated for severe deformities causing pain, function and cosmetic problems. In a growing bone, major surgical intervention like osteotomy with internal or external fixation can be avoided by growth modulation (hemiepiphysiodesis) using 8-plates. Our aim is to review the published literature on the use of 8-plates for deformity correction. Methods: We conducted a systematic review on 8-plate growth modulation for coronal deformity correction...
March 2018: Journal of Orthopaedics
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