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https://www.readbyqxmd.com/read/29471520/effect-of-exposure-to-second-hand-smoke-from-husbands-on-biochemical-hyperandrogenism-metabolic-syndrome-and-conception-rates-in-women-with-polycystic-ovary-syndrome-undergoing-ovulation-induction
#1
Jian Li, Q Wu, Xiao-Ke Wu, Zhong-Ming Zhou, Ping Fu, Xiu-Hua Chen, Ying Yan, Xin Wang, Zheng-Wang Yang, Wei-Li Li, Elisabet Stener-Victorin, Richard S Legro, Ernest Hung-Yu Ng, Heping Zhang, Ben Willem J Mol, Chi Chiu Wang
STUDY QUESTION: Does second-hand smoke (SHS) exposure from husbands have adverse effects on sex hormones, metabolic profiles, clinical phenotypes and fertility outcomes in women with polycystic ovary syndrome (PCOS) undergoing ovulation induction? SUMMARY ANSWER: SHS exposure is associated with worsened biochemical hyperandrogenism, higher incidence of metabolic syndrome and reduced conception rates in women with PCOS. WHAT IS KNOWN ALREADY: Smoking in women impairs fecundity at some stages of the reproductive process including folliculogenesis, embryo transport, endometrial angiogenesis and uterine blood flow...
February 20, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29471331/cross-cultural-validation-and-extension-of-the-clinical-assessment-interview-for-negative-symptoms-cains-in-the-chinese-context-evidence-from-a-spectrum-perspective
#2
Dong-Jie Xie, Hai-Song Shi, Simon S Y Lui, Chuan Shi, Ying Li, Karen K Y Ho, Karen S Y Hung, Wen-Xiu Li, Zheng-Hui Yi, Eric F C Cheung, Ann M Kring, Raymond C K Chan
The Clinical Assessment Interview for Negative Symptoms (CAINS) was designed in accordance with the recent theory and research in social affective neuroscience and to address the psychometric and conceptual limitations of other instruments assessing negative symptoms. The present study aimed to provide a large-scale validation of the CAINS in China and examine its applicability and validity evidence across the schizophrenia spectrum. Using confirmatory factor analysis, our results replicated the original findings in the US development samples that the CAINS possesses a stable 2-factor structure, namely "motivation/pleasure" and "expression"...
February 20, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29471267/the-effectiveness-of-traditional-chinese-medicine-based-lifestyle-interventions-on-biomedical-psychosocial-and-behavioral-outcomes-in-individuals-with-type-2-diabetes-a-systematic-review-with-meta-analysis
#3
REVIEW
Xingfeng Yu, Janita P C Chau, Lanting Huo
BACKGROUND: Integrative diabetes care, which combines conventional diabetes therapy with traditional Chinese medicine (TCM)-based interventions, has gained popularity worldwide. Numerous TCM-based lifestyle modification approaches have been proposed for individuals with type 2 diabetes (T2DM). OBJECTIVES: To synthesize and present the best available evidence on the effectiveness of TCM-based lifestyle interventions in individuals with T2DM. DESIGN: We undertook a systematic review of randomized controlled trials or controlled clinical trials...
February 19, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29471209/genetic-engineering-of-host-organisms-for-pharmaceutical-synthesis
#4
REVIEW
Joseph H Collins, Eric M Young
Pharmaceutical production hosts may be derived from almost any organism, from Chinese Hamster Ovary (CHO) cell lines to isolated actinomycetes. Each host can be improved, historically only through adaptive evolution. Recently, the maturation of organism engineering has expanded the available models, methods, and tools for altering host phenotypes. New tools like CRISPR-associated endonucleases promise to enable precise cellular reprogramming and to access previously intractable hosts. In this review, we discuss the most recent advances in engineering several types of pharmaceutical production hosts...
February 19, 2018: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/29471208/understanding-biopharmaceutical-production-at-single-nucleotide-resolution-using-ribosome-footprint-profiling
#5
REVIEW
Ioanna Tzani, Craig Monger, Paul Kelly, Niall Barron, Ronan M Kelly, Colin Clarke
Biopharmaceuticals such as monoclonal antibodies have revolutionised the treatment of a variety of diseases. The production of recombinant therapeutic proteins, however, remains expensive due to the manufacturing complexity of mammalian expression systems and the regulatory burden associated with administrating these medicines to patients in a safe and efficacious manner. In recent years, academic and industrial groups have begun to develop a greater understanding of the biology of host cell lines, such as Chinese hamster ovary (CHO) cells and utilise that information for process development and cell line engineering...
February 19, 2018: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/29471160/persistent-first-intersegmental-artery-pfia-visualized-by-three-dimensional-computed-tomography-angiography-in-chinese-population
#6
Haocong Zhang, Wei Chai, Shuang Wang, Yan Wang, Hongwei Li
BACKGROUND: Persistent first intersegmental artery (PFIA) is one of the most frequently vertebral artery (VA) variations. The presence of PFIA obviously increases the complexity and difficulty of vertebral lesion treatment. Thus, preoperative detection of PFIA is necessary to increase the successful rate of surgeries. We attempted to evaluate the utility value of three-dimension (3D) computed tomography angiography (CTA) for detecting PFIA in the north Chinese population. MATERIALS AND METHODS: Consecutive patients subjected to CTA between June 2012 and March 2014 were recruited from 5 clinical centers in the north of China...
February 19, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29471102/high-fructose-diet-induced-metabolic-syndrome-pathophysiological-mechanism-and-treatment-by-traditional-chinese-medicine
#7
REVIEW
Ying Pan, Ling-Dong Kong
Fructose is a natural monosaccharide broadly used in modern society. Over the past few decades, epidemiological studies have demonstrated that high fructose intake is an etiological factor of metabolic syndrome (MetS). This review highlights research advances on fructose-induced MetS, especially the underlying pathophysiological mechanism as well as pharmacotherapy by traditional Chinese medicine (TCM), using the PubMed, Web of science, China National Knowledge Infrastructure, China Science and Technology Journal and Wanfang Data...
February 19, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29471085/houttuynia-cordata-polysaccharides-ameliorate-pneumonia-severity-and-intestinal-injury-in-mice-with-influenza-virus-infection
#8
Haiyan Zhu, Xiaoxiao Lu, Lijun Ling, Hong Li, Yingye Ou, Xunlong Shi, Yan Lu, Yunyi Zhang, Daofeng Chen
ETHNOPHARMACOLOGICAL RELEVANCE: Hottuynia cordata is an important traditional Chinese medicine for the treatment of respiratory diseases including bacterial and viral infections. Polysaccharides isolated from Houttuynia cordata (HCP), as its main ingredients, have been demonstrated to ameliorate the LPS-induced acute lung injury in mice. The study aimed to determine the protective effects of HCP on multiple organ injury in influenza A virus (IAV) H1N1 infected mice and its primary mechanisms in anti-inflammation and immune regulation...
February 19, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29470860/investigation-of-the-in-vivo-metabolism-of-harpagoside-and-distribution-of-its-metabolites-in-rats-by-hplc-it-tof-ms-n
#9
Jing-Zhe Wang, Yi-Fan Zhang, Feng Xu, Ming-Ying Shang, Guang-Xue Liu, Shao-Qing Cai
Harpagoside, an iridoid glycoside, is the major bioactive constituent of the traditional Chinese medicine Scrophulariae Radix. High-performance liquid chromatography with a diode array detector combined with electrospray ionization ion trap time-of-flight multistage mass spectrometry (HPLC-ESI-IT-TOF-MSn ) was used to profile and identify the metabolites of harpagoside in rats in vivo and to study the distribution of these metabolites in rats for the first time. A total of 45 metabolites were identified, 37 of which were postulated to be new compounds...
February 22, 2018: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29470809/receiving-hiv-serostatus-disclosure-from-partners-before-sex-results-from-an-online-survey-of-chinese-men-who-have-sex-with-men
#10
Weiming Tang, Chuncheng Liu, Bolin Cao, Stephen W Pan, Ye Zhang, Jason Ong, Hongyun Fu, Baoli Ma, Rong Fu, Bin Yang, Wei Ma, Chongyi Wei, Joseph D Tucker
HIV serostatus disclosure before sex can facilitate serosorting, condom use and potentially decrease the risk of HIV acquisition. However, few studies have evaluated HIV serostatus disclosure from partners before sex. We examined the rate and correlates of receiving HIV serostatus disclosure from regular and casual male partners before sex among an online sample of men who have sex with men (MSM) in China. An online cross-sectional study was conducted among MSM in eight Chinese cities in July 2016. Participants completed questions covering sociodemographic information, sexual behaviors, HIV testing (including HIV self-testing) history, self-reported HIV status, and post-test violence...
February 22, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29470762/intergenerational-transmission-of-educational-aspirations-in-chinese-families-identifying-mediators-and-moderators
#11
Nini Wu, Yang Hou, Qian Wang, Chengfu Yu
Parents' educational aspirations for youth play an important role in shaping youth's own educational aspirations; however, little is known about how and in what context parents may transmit their aspirations to youth effectively. This is of particular interest and import to be examined in Chinese families, given Chinese cultural emphasis on educational achievement and Chinese youth's outstanding academic performance internationally. By integrating several key theories of motivation and parental socialization (i...
February 22, 2018: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/29470561/safety-and-efficacy-of-cosmetic-augmentation-of-the-nasal-tip-and-nasal-dorsum-with-expanded-polytetrafluoroethylene-a-randomized-clinical-trial
#12
Yifei Gu, Wenxin Yu, Yunbo Jin, Hui Chen, Gang Ma, Shih-Jen Chang, Xiaoxi Lin
Importance: Expanded polytetrafluoroethylene (ePTFE) is a widely used alloplast, but studies of augmentation of the nasal tip and nasal dorsum with ePTFE are lacking. Objective: To investigate whether attaching the conchal cartilage as shield grafts at the distal end of the graft can prevent extrusion and whether the use of ePTFE in the nasal tip can achieve a stable aesthetic outcome. Design, Setting, and Participants: A randomized clinical trial was performed from April 1, 2006, to October 31, 2008...
February 22, 2018: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29470484/the-characteristic-of-asthma-control-among-nasal-diseases-population-results-from-a-cross-sectional-study
#13
Jiangtao Lin, Jie Gao, Kefang Lai, Xin Zhou, Bei He, Jianying Zhou, Changzheng Wang
Asthma affects a large number of patients in China, but comprehensive evaluation of risks associated with poor asthma control in asthmatic patients with nasal diseases was still limited. We conducted this study to provide a comprehensive estimate of asthma control in Chinese asthma patients with combined nasal diseases, to explore the effect of kinds of nasal diseases on the asthma control, and to identify risk factors associated with uncontrolled asthmatic patients with combined nasal diseases. 1756 asthma patients concomitant with nasal diseases aged ≥17 years and representing all regions of mainland China were surveyed...
2018: PloS One
https://www.readbyqxmd.com/read/29470473/liver-abscess-contemporary-presentation-and-management-in-a-western-population
#14
Kareem Osman, Sanket Srinivasa, Jonathan Koea
AIM: Historically, liver abscesses (LA) affected elderly, immunocompromised patients and were characterised by high morbidity and mortality, however there are no data pertaining to a New Zealand population with little information surrounding recent management trends. METHODS: A retrospective review of demographic characteristics, clinical management and microbiological data on patients presenting with liver abscess between 2005-2014 was conducted. RESULTS: Fifty-seven patients [37 males, median age 64 (range 15-87)] presented with LA and most patients were not comorbid...
February 23, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29470415/exclusive-breastfeeding-rate-and-complementary-feeding-indicators-in-china-a-national-representative-survey-in-2013
#15
Yifan Duan, Zhenyu Yang, Jianqiang Lai, Dongmei Yu, Suying Chang, Xuehong Pang, Shan Jiang, Huanmei Zhang, Ye Bi, Jie Wang, Robert W Scherpbier, Liyun Zhao, Shian Yin
Appropriate infant and young child feeding could reduce morbidity and mortality and could improve cognitive development of children. However, nationwide data on exclusive breastfeeding and complementary feeding status in China are scarce. The aim of this study was to assess current exclusive breastfeeding and complementary feeding status in China. A national representative survey (Chinese National Nutrition and Health Survey) of children aged under 6 years was done in 2013. Stratified multistage cluster sampling was used to select study participants...
February 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29469464/-investigation-and-morphological-observation-of-histiostoma-feroniarum-breeding-in-chinese-herbal-medicine-rhizoma-zingiberis
#16
Chai Qiang, Guo Jiao-Jiao, Tao Ning, Li Chao-Pin
OBJECTIVE: To understand the breeding situation of Histiostoma feroniarum in Chinese herbal medicine Rhizoma Zingiberis. METHODS: The Rhizoma Zingiberis sold on the market was selected and brushed. The dust from Rhizoma Zingiberis was screened under a microscope to search the mites. The mites were made into specimens to identify the species. RESULTS: The mites were H. feroniarum . Totally 14 mites were found in 100 g dust sample, with the density of breeding of 0...
March 21, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469463/-carpoglyphus-lactis-infestation-in-stored-traditional-chinese-medicine-arillus-longan
#17
Hong Yong, Chai Qiang, Zhan Xiao-Dong, Li Chao-Pin
OBJECTIVE: To investigate the breeding of Carpoglyphus lactis in the storage Arillus longan , so as to provide the evidence for preventing the harm of C. lactis to traditional Chinese medicine. METHODS: Chinese herbal medicine warehouses were chosen as survey sites according to the breeding habits of mites, and the A. longan samples were stored more than 6 months. The mites were isolated and identified under a microscope. RESULTS: The C. lactis breeding rate was 20...
July 27, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469342/-precision-control-is-essential-to-achieve-the-goal-of-schistosomiasis-elimination-in-china-summary-of-the-second-forum-on-schistosomiasis-control-in-china
#18
(no author information available yet)
The Second Forum on Schistosomiasis Control in China was successfully held in Jiangsu Institute of Parasitic Diseases during the period between 21th and 23th, September, 2017. Based on the topic "Implementation of precision control to accelerate the progress towards schistosomiasis elimination", the forum discussed three macro problems pertaining to how to improve the theory and policy of precision control during the progress towards schistosomiasis elimination in China, and six technical problems regarding how to achieve more precise management of the residual sources of infections and more precise monitoring of transmission risk...
October 15, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469336/-analysis-of-academic-impact-of-publications-from-national-institute-of-parasitic-diseases-chinese-center-for-disease-control-and-prevention-based-on-scie-database-in-recent-five-years
#19
Li Zhen, Zheng Bin
OBJECTIVE: To describe the academic impact of publications from National Institute of Parasitic Diseases (NIPD), Chinese Center for Disease Control and Prevention, so as to give the quantity evidence for scientific research decision making. METHODS: The SCIE papers of NIPD published from 2011-2015 were searched and statistically analyzed. The number of published papers, citation frequencies, h-index, and funding resources were analyzed. The academic impact of the institute was assessed according to these data...
March 2, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469188/indeterminate-cell-histiocytosis-in-a-chinese-patient-with-florid-and-extensive-nodular-lesions-and-mixed-intermediate-cell-and-macrophage-monocyte-bilineage
#20
Qiping Chen, Joyce Siong-See Lee, Weiting Michelle Liang, Mei Fung Chan, Ramón M Pujol, Requena Luis, Suat Hoon Tan
Indeterminate cell histiocytosis (ICH) is an extremely rare cutaneous neoplastic disorder. It has the immunophenotypic features of both Langerhans and non-Langerhans cell histiocytosis. We report here a case of a healthy young Chinese woman who presented with disfiguring thick, infiltrated cutaneous nodules on the face, trunk and extremities which appeared progressively over a period of 4 years. No systemic involvement has been detected so far. Results of a skin biopsy showed diffuse dermal infiltration of histiocytoid cells with indented nuclei and positive staining for S100 and CD1a and negativity for CD207 (langerin)...
February 22, 2018: Journal of Cutaneous Pathology
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