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https://www.readbyqxmd.com/read/29806905/personalized-medicine-is-the-postgenomic-condition
#1
REVIEW
Carolyn P Neuhaus
When President Obama laid out his vision for the U.S. Precision Medicine Initiative in a 2016 Boston Globe op-ed, he cautioned, "[I]t only works if we collect enough information first." "Collecting information" is an apt way to describe the subject of both books reviewed here. Jenny Reardon's The Postgenomic Condition: Ethics, Justice, and Knowledge after the Genome traces the history of the Human Genome Project and efforts around the globe to obtain blood samples to extract not only genetic data but also meaning from them...
May 2018: Hastings Center Report
https://www.readbyqxmd.com/read/29806150/personality-and-political-preferences-over-time-evidence-from-a-multi-wave-longitudinal-study
#2
Pierce D Ekstrom, Christopher M Federico
OBJECTIVE: To investigate how the relations between the Big Five personality traits and political preferences develop over a campaign. METHOD: We rely on a 6-wave nationwide longitudinal survey from the 2008 U.S. election that included 20,000 respondents. Mean age: 49 (SD=15). 53% of respondents were women, 47% men. 82% were White, 8% Black, 6% Hispanic/Latino, 1% Asian, 1% Native American, and 2% other. Survey weights were applied to approximate a representative sample of the U...
May 27, 2018: Journal of Personality
https://www.readbyqxmd.com/read/29740500/have-geopolitics-influenced-decisions-on-american-health-foreign-assistance-efforts-during-the-obama-presidency
#3
REVIEW
Vin Gupta, Alexander C Tsai, Alexandre Mason-Sharma, Eric P Goosby, Ashish K Jha, Vanessa B Kerry
Background: This study sought to characterize the possible relationship between US geopolitical priorities and annual decisions on health foreign assistance among recipient nations between 2009 and 2016. Methods: Data on total planned United States (US) foreign aid and health aid were collected for the 194 member nations of the World Health Organization (WHO) from publicly available databases. Trends in per-capita spending were examined between 2009 and 2016 across the six regions of the WHO (Africa, Americas, Eastern Mediterranean, Europe, Southeast Asia, and the Western Pacific)...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29736813/participatory-budgeting-could-it-diminish-health-disparities-in-the-united-states
#4
EDITORIAL
Carolin Hagelskamp, David Schleifer, Chloe Rinehart, Rebecca Silliman
Participatory budgeting (PB)-a democratic process where ordinary residents decide directly how to spend part of a public budget-has gained impressive momentum in US municipalities, spreading from one pilot project in Chicago's 49th ward in 2009 to 50 active PB processes across 14 cities in 2016-2017. Over 93,600 US residents voted in a PB process in 2015-2016, deciding over a total of about $49.5 million and funding 264 projects intended to improve their communities. The vast majority of US PB processes take place in large urban centers (e...
May 7, 2018: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/29697447/long-term-outcomes-of-laparoscopic-versus-open-surgery-for-clinical-stage-ii-iii-gastric-cancer-a-multicenter-cohort-study-in-japan-loc-a-study
#5
Takahiro Kinoshita, Ichiro Uyama, Masanori Terashima, Hirokazu Noshiro, Eishi Nagai, Kazutaka Obama, Yutaka Tamamori, Toshinaga Nabae, Michitaka Honda, Takayuki Abe
OBJECTIVE: A large-scale multicenter historical cohort study was conducted to investigate the efficacy of laparoscopic gastrectomy (LG) in comparison to open gastrectomy (OG) for locally advanced gastric cancer. BACKGROUND: LG is now practiced widely, but its applicability for advanced gastric cancer is still controversial. As oncologic outcomes of randomized trials are still pending, there is an urgent need for information that would be relevant to current practice...
April 24, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29655401/classic-provocative-and-or-influential-a-twin-study-sampler-twin-research-reviews-twin-pregnancies-with-and-without-polycystic-ovary-syndrome-ectopic-twin-pregnancy-sex-differences-in-cognition-maternal-cardiac-hemodynamics-newsworthy-president-obama-s-portrait
#6
Nancy L Segal
Selected twin research papers that are classic, provocative, and/or influential are surveyed. Many papers meet these criteria, so those chosen reflect the opinion of the author. Reviews of recent research on twin pregnancies with and without polycystic ovary syndrome, ectopic pregnancy, sex differences in cognition and maternal cardiac hemodynamics follow. Newsworthy twin-based items, including President Obama's portrait artist, the financial activities of the Winkelvoss twins, a set of triplet fashion models and the experience of seeing oneself in a painting, are summarized...
June 2018: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29649407/undermining-the-aca-through-the-executive-branch-and-federalism-what-the-trump-administration-s-approach-to-health-reform-means-for-older-americans
#7
David K Jones, Michael K Gusmano, Pamela Nadash, Edward Alan Miller
The ACA has survived multiple existential threats in the legislative and judicial branches, including dozens of congressional attempts at repeal and two major Supreme Court cases. Even as it seems that the ACA is here to stay, what the law accomplishes is far from settled. The Trump administration is using executive powers to weaken the law, in many cases using the same powers that President Obama used to strengthen the effects of the reform. States have responded by seeking flexibility to pursue reforms, such as work requirements, that could not pass Congress and that were not allowed by the Obama administration...
April 12, 2018: Journal of Aging & Social Policy
https://www.readbyqxmd.com/read/29550983/destination-memory-in-traumatic-brain-injuries
#8
Amina Wili Wilu, Yann Coello, Mohamad El Haj
Destination memory, which is socially driven, refers to the ability to remember to whom one has sent information. Our study investigated destination memory in patients with traumatic brain injuries (TBIs). Patients and control participants were invited to tell proverbs (e.g., "the pen is mightier than the sword") to pictures of celebrities (e.g., Barack Obama). Then they were asked to indicate to which celebrity they had previously told the proverbs. Besides the assessment of destination memory, participants performed a binding task in which they were required to associate letters with their corresponding location...
March 17, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29544953/quantitative-assessment-of-paravalvular-leakage-after-transcatheter-aortic-valve-replacement-using-a-patient-specific-pulsatile-flow-model
#9
Yutaka Tanaka, Shigeru Saito, Saeko Sasuga, Azuma Takahashi, Yusuke Aoyama, Kazuto Obama, Mitsuo Umezu, Kiyotaka Iwasaki
BACKGROUND: Quantitative assessment of post-transcatheter aortic valve replacement (TAVR) aortic regurgitation (AR) remains challenging. We developed patient-specific anatomical models with pulsatile flow circuit and investigated factors associated with AR after TAVR. METHODS: Based on pre-procedural computed tomography (CT) data of the six patients who underwent transfemoral TAVR using a 23-mm SAPIEN XT, anatomically and mechanically equivalent aortic valve models were developed...
May 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29534647/implicit-and-explicit-racial-attitudes-changed-during-black-lives-matter
#10
Jeremy Sawyer, Anup Gampa
Lab-based interventions have been ineffective in changing individuals' implicit racial attitudes for more than brief durations, and exposure to high-status Black exemplars like Obama has proven ineffective in shifting societal-level racial attitudes. Antiracist social movements, however, offer a potential societal-level alternative for reducing racial bias. Racial attitudes were examined before and during Black Lives Matter (BLM) and its high points of struggle with 1,369,204 participants from 2009 to 2016...
March 1, 2018: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/29521196/significance-of-oxidized-low-density-lipoprotein-in-body-fluids-as-a-marker-related-to-diseased-conditions
#11
Hiroyuki Itabe, Rina Kato, Naoko Sasabe, Takashi Obama, Matsuo Yamamoto
Oxidatively modified low-density lipoprotein (oxLDL) is known to be involved in various diseases, including cardiovascular diseases. The presence of oxLDL in the human circulatory system and in atherosclerotic lesions has been demonstrated using monoclonal antibodies. Studies have shown the significance of circulating oxLDL in various systemic diseases, including acute myocardial infarction and diabetic mellitus. Several different enzyme-linked immunosorbent assay (ELISA) procedures to measure oxLDL were utilized...
March 6, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29509590/time-to-first-line-art-failure-and-time-to-second-line-art-switch-in-the-iedea-pediatric-cohort
#12
Kara Wools-Kaloustian, Irene Marete, Samuel Ayaya, Annette H Sohn, Lam Van Nguyen, Shanshan Li, Valériane Leroy, Beverly S Musick, Jamie E Newman, Andrew Edmonds, Mary-Ann Davies, François T Eboua, Marie-Thérèse Obama, Marcel Yotebieng, Shobna Sawry, Lynne M Mofenson, Constantin T Yiannoutsos
BACKGROUND: Globally, 49% of the estimated 1.8 million children living with HIV are accessing antiretroviral therapy (ART). There are limited data concerning long-term durability of first-line ART regimens and time to transition to second-line. METHODS: Children initiating their first ART regimen between 2 and 14 years of age and enrolled in one of 208 sites in 30 Asia-Pacific and African countries participating in the Pediatric International Epidemiology Databases to Evaluate AIDS consortium were included in this analysis...
June 1, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29338717/risk-factors-for-acute-respiratory-infections-in-children-under-five-years-attending-the-bamenda-regional-hospital-in-cameroon
#13
Alexis A Tazinya, Gregory E Halle-Ekane, Lawrence T Mbuagbaw, Martin Abanda, Julius Atashili, Marie Therese Obama
BACKGROUND: Acute respiratory infections (ARI) are a leading cause of morbidity and mortality in under-five children worldwide. About 6.6 million children less than 5 years of age die every year in the world; 95% of them in low-income countries and one third of the total deaths is due to ARI. This study aimed at determining the proportion of acute respiratory infections and the associated risk factors in children under 5 years visiting the Bamenda Regional Hospital in Cameroon. METHODS: A cross-sectional analytic study involving 512 children under 5 years was carried out from December 2014 to February 2015...
January 16, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29294669/college-sexual-assault-and-campus-climate-for-sexual-and-gender-minority-undergraduate-students
#14
Robert W S Coulter, Susan R Rankin
Sexual- and gender-minority (e.g., lesbian, gay, bisexual, and transgender) undergraduate students are at greater risk for sexual assault victimization than their cisgender (i.e., nontransgender) heterosexual peers. However, few studies have examined how social environments affect sexual assault victimization among sexual- and gender-minority undergraduate students. Nevertheless, this research area was identified as a priority by the Institute of Medicine as well as President Barack Obama's White House Task Force to Protect Students From Sexual Assault...
March 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29245445/increasing-diversity-of-land-planarians-platyhelminthes-geoplanidae-in-the-interior-atlantic-forest-with-the-description-of-two-new-species-and-new-records-from-argentina
#15
Lisandro Negrete, Francisco Brusa
Here, we describe two new species of land planarians of the genera Pasipha and Imbira from the Atlantic Forest of Argentina: Pasipha quirogai sp. nov. and Imbira negrita sp. nov. Their external features and internal anatomy distinguish them from their congeners. Pasipha quirogai sp. nov. is about 40mm long, characterized by brown beige dorsal pigmentation with a golden yellow median band and thin graphite black para-median stripes, cylindrical pharynx, extrabulbar prostatic vesicle with paired proximal portion, male atrium with small folds in its proximal part, and female canal opening into the dorso-caudal wall of the female atrium...
December 4, 2017: Zootaxa
https://www.readbyqxmd.com/read/29132162/what-recent-history-has-taught-us-about-responding-to-emerging-infectious-disease-threats
#16
Catharine I Paules, Robert W Eisinger, Hilary D Marston, Anthony S Fauci
Presidential administrations face any number of unexpected crises during their tenure, and global pandemics are among the most challenging. As of January 2017, one of the authors had served under 5 presidents as the director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. During each administration, the government faced unexpected pandemics, ranging from the HIV/AIDS pandemic, which began during the Reagan administration, to the recent Zika outbreak in the Americas, which started during the Obama administration...
December 5, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29118692/statistical-image-properties-in-large-subsets-of-traditional-art-bad-art-and-abstract-art
#17
Christoph Redies, Anselm Brachmann
Several statistical image properties have been associated with large subsets of traditional visual artworks. Here, we investigate some of these properties in three categories of art that differ in artistic claim and prestige: (1) Traditional art of different cultural origin from established museums and art collections (oil paintings and graphic art of Western provenance, Islamic book illustration and Chinese paintings), (2) Bad Art from two museums that collect contemporary artworks of lesser importance (© Museum Of Bad Art [MOBA], Somerville, and Official Bad Art Museum of Art [OBAMA], Seattle), and (3) twentieth century abstract art of Western provenance from two prestigious museums (Tate Gallery and Kunstsammlung Nordrhein-Westfalen)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29114872/racism-in-trump-s-america-reflections-on-culture-sociology-and-the-2016-us-presidential-election
#18
Lawrence D Bobo
Despite much positive change in the post civil rights era, U.S. notions of racism and white supremacy remain powerful elements of American culture. The adaptability and enduring power of these forces can be seen in the emergence of a new historical epoch best describe as the era of Laissez Faire Racism. Prevalent attitudes among white Americans, certain theoretical arguments and hypotheses in American sociology, as well the election of Donald Trump rest upon the on-going operation of racism. In particular, I attribute Trump's electoral success to three critical dilemmas of race that defined contours of the 2016 presidential election: (1) worsening economic inequality in the presence of rapidly changing ethno-racial demography; (2) intensified political partisanship in the presence of well-institutionalized racially coded campaign strategies and rhetoric; and (3) the failure of the Clinton campaign to simultaneously champion the interests of working and middle class families and galvanize the previously powerful multiracial Obama coalition...
November 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/29052640/trump-epa-begins-push-to-overturn-obama-era-climate-regulation
#19
Jeff Tollefson
No abstract text is available yet for this article.
October 10, 2017: Nature
https://www.readbyqxmd.com/read/28956027/the-impact-of-changes-in-medicare-s-physician-payment-system-on-critical-care
#20
Charles E Hobson, Azra Bihorac, Mehrnaz Hadian, Daniel L Herr, Thomas G Rainey, Frank B Cerra, Lena M Napolitano, John W Hoyt
In 2015 President Obama signed the Medicare Access and CHIP Reauthorization Act (MACRA) which repealed the Sustainable Growth Rate (SGR) mechanism for Medicare physician reimbursement and mandated that CMS develop alternative payment methodologies to "reward health care providers for giving better care not more just more care." MACRA makes 3 major changes to Medicare reimbursements: (1) it ends the SGR formula; (2) it establishes a new framework to reward physicians based on performance and health outcomes rather than volume; and (3) it aims to combine existing quality reporting programs into one streamlined system...
February 2017: Critical Connections: the Complete News Source for Critical Care Professionals
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