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JOURNAL ARTICLE
New Treatment modality for Burn Injury Related ARDS : High-Flow Nasal Oxygen Therapy in Major Burns.
Merve Akin, Huriye Bilge Tuncer, Ali Emre Akgün, Ezgi Erkılıç
Pulmonary insufficiency is the primary cause of death in cases of major burns accompanied by inhalation damage. It is important to consider the impact on the face and neck in flame burns. Early implementation of bronchial hygiene measures and oxygenation treatment in inhalation injury can reduce mortality. This case series presents the effects of high-flow nasal oxygen application on patient outcomes in major burns and inhalation injury. This report discusses three different patients. One patient, a 29-year-old male with 35% TBSA burns, received high-flow nasal oxygen (HFNO) treatment for inhalation injury on the sixth day after the trauma...
April 17, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
#22
JOURNAL ARTICLE
Amit Om, Jennifer Ledon, Richard G Bennett
No abstract text is available yet for this article.
April 16, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
#23
JOURNAL ARTICLE
Albin Sjöblom, Magnus Hedberg, Ida-Maria Forsberg, Frida Hoffman, Malin Jonsson Fagerlund
BACKGROUND: Preoxygenation before anaesthesia induction is routinely performed via a tight-fitting facemask or humidified high-flow nasal oxygen. We hypothesised that effective preoxygenation, assessed by end-tidal oxygen (EtO2) levels, can also be performed via a standard nasal cannula. OBJECTIVE: This study compared the efficacy of preoxygenation between a traditional facemask, humidified high-flow nasal oxygen and a standard nasal cannula. DESIGN: A volunteer, randomised, crossover study...
April 16, 2024: European Journal of Anaesthesiology
#24
JOURNAL ARTICLE
Zehua Jiang, Tian Lin, Aidi Lin, Xujia Liu, Xiaoting Mai, Jianwei Lin, Carol Y L Cheung, Haoyu Chen
PURPOSE: To investigate the topographic characters of inter-individual variations of the macular choroidal thickness (CT). METHODS: This was a retrospective study. Macular CT data for 900 0.2 × 0.2-mm grids from 410 healthy eyes were collected from swept-source optical coherence tomography. Following the analysis of factors associated with mean CT, the β-coefficients of the included associated factors in each grid were summarized for choroidal thickness changes analysis...
April 2, 2024: Translational Vision Science & Technology
#25
REVIEW
M Ammar Kalas, Irene Sarosiek, Richard W McCallum
INTRODUCTION: Gastroparesis is a chronic disorder characterized by decreased gastric emptying and presents with nausea, vomiting, and abdominal pain which impacts patients' quality of life greatly. The treatment modalities available for gastroparesis have been expanding over the past 2 decades. Currently there are multiple options available for gastroparesis albeit with only one FDA approved medication until June of 2021. AREAS COVERED: We review the different treatments available for gastroparesis and discuss the recently FDA approved intranasal formulation of metoclopramide...
April 17, 2024: Expert Opinion on Pharmacotherapy
#26
JOURNAL ARTICLE
Yasmim Carvalho Telson, Renata Maria Moreira Moraes Furlan, Rafael Augusto Magalhães Ferreira, Matheus Pereira Porto, Andréa Rodrigues Motta
PURPOSE: To present a method for analyzing breathing modes with infrared thermography. METHODS: This exploratory cross-sectional study used 38 thermal images of inspiration and expiration with nasal breathing and simulated mouth breathing in four nasal breathers without respiratory complaints. Three different data selection forms (line, rectangle, and ellipse) were used to extract the minimum, mean, and maximum temperatures of the regions of interest (nose and mouth) using the FLIR Tools® software...
2024: CoDAS
#27
JOURNAL ARTICLE
F-T Lee, L Sun, A Szabo, N Milligan, A Saini, D Chetan, J-L Hunt, C K Macgowan, L Freud, E Jaeggi, T Van Mieghem, J Kingdom, S P Miller, M Seed
OBJECTIVES: Fetuses with single ventricle physiology (SVP) exhibit reductions in fetal cerebral oxygenation with associated delays in fetal brain growth and neurodevelopmental outcomes. Maternal supplemental oxygen (MSO) has been proposed to improve fetal brain growth but current evidence on dosing, candidacy, and outcomes are limited. In this pilot study, we evaluated the safety and feasibility of continuous low-dose MSO in the setting of SVP. METHODS: This single-centre, open-label, pilot phase 1 safety and feasibility clinical trial included 25 pregnant individuals with a fetal diagnosis of SVP...
April 17, 2024: Ultrasound in Obstetrics & Gynecology
#28
JOURNAL ARTICLE
Helga Elidottir, Selma R Bjarnadottir, Olafur Baldursson, Brynja Jonsdottir
BACKGROUND: Cystic fibrosis (CF) is most common in populations of Northern European ancestry where the F508del variant predominates. In 2020, Iceland became a member of the European Cystic Fibrosis Society Patient Registry, and we launched an epidemiological study of CF in Iceland. The study aimed to determine the prevalence and the genetic variants present in the country. Furthermore, we aimed to describe the previous and the current situation regarding lung function, infections, complications, treatment, and follow-up to understand the strengths and weaknesses of CF care in Iceland...
April 17, 2024: Pediatric Pulmonology
#29
JOURNAL ARTICLE
Raj M Vyas, Wassim Najjar, Joseph E Losee, Ann W Kummer, Usama S Hamdan
OBJECTIVE: The inaugural Cleft Summit aimed to unite experts and foster interdisciplinary collaboration, seeking a collective understanding of velopharyngeal insufficiency (VPI) management. DESIGN: An interactive debate and conversation between a multidisciplinary cleft care team on VPI management. SETTING: A two-hour discussion within a four-day comprehensive cleft care workshop (CCCW). PARTICIPANTS: Thirty-two global leaders from various cleft disciplines...
April 17, 2024: Cleft Palate-craniofacial Journal
#30
JOURNAL ARTICLE
Irina Shumilova, Pavel Prutnikov, Ali Mazloum, Alena Krotova, Nikita Tenitilov, Olga Byadovskaya, Ilya Chvala, Larisa Prokhvatilova, Alexander Sprygin
Lumpy skin disease (LSD) is a transboundary viral infection, affecting cattle with characteristic manifestations involving multiple body systems. A distinctive characteristic of lumpy skin disease is the subclinical disease manifestation wherein animals have viremia and shed the virus through nasal and ocular discharges, while exhibiting no nodules but enlarged lymph nodes that are easily oversighted by inexperienced vets. Further research on the role of subclinically ill animals in the transmission of LSD virus (LSDV) can contribute to the development of more effective tools to control the disease worldwide...
2024: Frontiers in Veterinary Science
#31
René Agustín Flores-Franco, Carlos Mauricio González-Ponce, Victor Irigoyen-Monroy
No abstract text is available yet for this article.
2024: Open Respir Arch
#32
JOURNAL ARTICLE
T Jones Raja Devathambi, Nalini Aswath
OBJECTIVES: This prospective study was performed with cone-beam computed tomography (CBCT) images for evaluating canalis sinuosus (CS), determine its location and diameter in relation to gender, age, and distances from important structures, including floor of nasal cavity, incisive foramen, edge of buccal cortical bone, and palatal cortical bone. MATERIAL AND METHODS: The scans of 650 patients in total were included in this prospective analysis. Gender, age, the position of the CS, its presence or absence, diameter, and its location in reference to the adjacent teeth were the factors that were noted...
2024: Journal of Clinical Imaging Science
#33
Peripapillary pachychoroid syndrome successfully treated with topical prednisolone acetate 1% drops.
Lojain A Azizalrahman, Abdullah N Almousa, Fadwa Al Adel, Abdulrahman F AlBloushi
Peripapillary pachychoroid syndrome (PPS) is a rare disease characterized by choroidal thickening around the optic disc. Visual acuity might be impaired secondary to the associated peripapillary intraretinal and/or subretinal fluids. We reported a case of a 70-year-old male patient who presented with a gradual bilateral decrease in vision. His best-corrected visual acuity was 20/60 in the right eye and 20/25 in the left eye. Dilated fundus examination showed yellowish peripapillary lesions and intraretinal fluid (IRF) surrounding the optic disc in both eyes...
2024: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
#34
REVIEW
Blanca E R G Bica, Alexandre Wagner S de Souza, Ivânio Alves Pereira
Relapsing polychondritis is a rare multisystem disease involving cartilaginous and proteoglycan-rich structures. The diagnosis of this disease is mainly suggested by the presence of flares of inflammation of the cartilage, particularly in the ears, nose or respiratory tract, and more rarely, in the presence of other manifestations. The spectrum of clinical presentations may vary from intermittent episodes of painful and often disfiguring auricular and nasal chondritis to an occasional organ or even life-threatening manifestations such as lower airway collapse...
April 16, 2024: Advances in Rheumatology
#35
JOURNAL ARTICLE
Chen Ding, Libo Mao, Yinghong Lu, Sai Wu, Wenyan Ji
BACKGROUND: Obstructive sleep apnea (OSA) has been shown to be an important risk factor for cardiovascular disease (CVD), and intermittent hypoxia is an important pathogenetic factor for it. In the clinic, it was found that most CVD patients combined with OSA were also combined with solitary pulmonary nodules (SPN) or thyroid nodules (TN). Are these disorders related to intermittent hypoxia? One study showed that intermittent hypoxia is a pathogenic factor for lung cancer in mice, but there have been no clinical reports...
April 17, 2024: Sleep & Breathing
#36
JOURNAL ARTICLE
Thomas Radulesco, Dario Ebode, Justin Michel
BACKGROUND: Liquid rhinoplasty, a non-surgical procedure using hyaluronic acid (HA) to reshape and refine the nose, has gained in popularity as an alternative to traditional surgical rhinoplasty although its results are not definitive. However, the lack of standardized injection protocols has raised concerns about treatment consistency and patient safety. OBJECTIVES: In this article, the authors propose a systematic protocol for the most common indications of liquid rhinoplasty...
April 16, 2024: Aesthetic Plastic Surgery
#37
JOURNAL ARTICLE
Milind Sagar, Prahlad Dharmavaram Rajasekhar, Chirom Amit Singh, Hena Khandkar
Nasal obstruction is a commonly reported issue in the Otorhinolaryngology Outpatient Department. In this case, an early adolescent boy with a long-standing problem of right-sided nasal obstruction since childhood sought consultation. Diagnostic nasal endoscopy revealed a deviation of the nasal septum to the left, coupled with right inferior turbinate hypertrophy, all overlying healthy mucosa. A CT scan of the nose and paranasal sinuses further identified a bony hyperdense lesion with ground glass attenuation, confined to the right inferior turbinate...
April 16, 2024: BMJ Case Reports
#38
JOURNAL ARTICLE
Kaori Tateyama, Shingo Umemoto, Shohei Iwano, Takashi Hirano, Masashi Suzuki
OBJECTIVE: This study aimed to examine the characteristics of nasal and imaging findings of sinonasal lesions in granulomatosis with polyangiitis (GPA) patients and how these lesions change over time in both the active and remission phases of the disease. METHODS: We retrospectively reviewed GPA patients with sinonasal lesions who were followed up at our department between January 2005 and December 2020. The following data were collected: age, sex, symptoms at initial presentation, anti-neutrophil cytoplasmic antibody (ANCA) type, and histopathological, nasal (initial and follow-up), and imaging (initial and follow-up) findings...
April 15, 2024: Auris, Nasus, Larynx
#39
JOURNAL ARTICLE
Gerard W Dougherty, Lawrence E Ostrowski, Tabea Nöthe-Menchen, Johanna Raidt, Andre Schramm, Heike Olbrich, Weining Yin, Patrick R Sears, Hong Dang, Amanda J Smith, Achim G Beule, Rim Hjeij, Niels Rutjies, Eric G Haarman, Saskia M Maas, Thomas W Ferkol, Peadar G Noone, Kenneth N Olivier, Diana C Bracht, Pascal Barbry, Laure-Emmanuelle Zaragosi, Morgane Fierville, Sabine Kliesch, Kai Wohlgemuth, Julia König, Sebastian George, Niki T Loges, Agathe Ceppe, Matthew R Markovetz, Hong Luo, Ting Guo, Hoda Rizk, Tarek Eldesoky, Katrin Dahlke, Karsten Boldt, Marius Ueffing, David B Hill, Yuan-Ping Pang, Michael R Knowles, Maimoona A Zariwala, Heymut Omran
RATIONALE: Bronchiectasis is a pathological dilatation of the bronchi in the respiratory airways associated with environmental or genetic causes (e.g., cystic fibrosis, primary ciliary dyskinesia and primary immunodeficiency disorders), but most cases remain idiopathic. OBJECTIVES: To identify novel genetic defects in unsolved cases of bronchiectasis presenting with severe rhinosinusitis, nasal polyposis, and pulmonary Pseudomonas aeruginosa infection. METHODS: DNA was analyzed by next-generation or targeted Sanger sequencing...
April 16, 2024: American Journal of Respiratory and Critical Care Medicine
#40
JOURNAL ARTICLE
David VanInsberghe, Dillon S McBride, Juliana DaSilva, Thomas J Stark, Max S Y Lau, Samuel S Shepard, John R Barnes, Andrew S Bowman, Anice C Lowen, Katia Koelle
Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these patterns remain poorly characterized in non-human hosts. Elucidating these dynamics is important to better understand IAV biology and the evolutionary processes that govern spillover into humans. Here, we sampled an IAV outbreak in pigs during a week-long county fair to characterize viral diversity and evolution in this important reservoir host. Nasal wipes were collected on a daily basis from all pigs present at the fair, yielding up to 421 samples per day...
April 16, 2024: PLoS Pathogens
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