keyword
MENU ▼
Read by QxMD icon Read
search

Stereotactic radiation

keyword
https://www.readbyqxmd.com/read/28237400/individualized-early-death-and-long-term-survival-prediction-after-stereotactic-radiosurgery-for-brain-metastases-of-non-small-cell-lung-cancer-two-externally-validated-nomograms
#1
Jaap D Zindler, Arthur Jochems, Frank J Lagerwaard, Rosemarijne Beumer, Esther G C Troost, Daniëlle B P Eekers, Inge Compter, Peter-Paul van der Toorn, Marion Essers, Bing Oei, Coen W Hurkmans, Anna M E Bruynzeel, Geert Bosmans, Ans Swinnen, Ralph T H Leijenaar, Philippe Lambin
INTRODUCTION: Commonly used clinical models for survival prediction after stereotactic radiosurgery (SRS) for brain metastases (BMs) are limited by the lack of individual risk scores and disproportionate prognostic groups. In this study, two nomograms were developed to overcome these limitations. METHODS: 495 patients with BMs of NSCLC treated with SRS for a limited number of BMs in four Dutch radiation oncology centers were identified and divided in a training cohort (n=214, patients treated in one hospital) and an external validation cohort n=281, patients treated in three other hospitals)...
February 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28237218/stereotactic-ablative-body-radiotherapy-for-the-treatment-of-spinal-oligometastases
#2
J H Chang, S Gandhidasan, R Finnigan, D Whalley, R Nair, A Herschtal, T Eade, A Kneebone, J Ruben, M Foote, S Siva
AIMS: To report multicentre outcomes of patients with spinal oligometastases treated with stereotactic ablative body radiotherapy (SABR). The primary objective was to estimate the widespread failure-free survival (WFFS) at 2 years - defined as freedom from metastases not amenable to local salvage therapy and death. MATERIALS AND METHODS: Patients with one to three metastases treated with spinal SABR between January 2010 and July 2014 at four academic institutions were included in this retrospective review...
February 22, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28230623/safety-and-accuracy-of-freehand-versus-navigated-iliac-screws-results-from-222-screw-placements
#3
Randall J Hlubek, Kaith K Almefty, David S Xu, Jay D Turner, U Kumar Kakarla
STUDY DESIGN: Retrospective review. OBJECTIVE: To compare the safety and accuracy of the freehand technique versus stereotactic navigation for placement of iliac screws. SUMMARY OF BACKGROUND DATA: Iliac screw fixation is often used to augment lumbosacral reconstruction in advanced spine disease to increase the likelihood of successful arthrodesis. Iliac screws can be placed with image guidance, using either intraoperative fluoroscopy or computed tomography (CT) to guide navigation...
February 22, 2017: Spine
https://www.readbyqxmd.com/read/28224113/intensity-modulated-radiation-therapy-with-stereotactic-body-radiation-therapy-boost-for-unfavorable-prostate-cancer-a-report-on-3-year-toxicity
#4
Ima Paydar, Abigail Pepin, Robyn A Cyr, Joseph King, Thomas M Yung, Elizabeth G Bullock, Siyuan Lei, Andrew Satinsky, K William Harter, Simeng Suy, Anatoly Dritschilo, John H Lynch, Thomas P Kole, Sean P Collins
BACKGROUND: Recent data suggest that intensity-modulated radiation therapy (IMRT) plus brachytherapy boost for unfavorable prostate cancer provides improved biochemical relapse-free survival over IMRT alone. Stereotactic body radiation therapy (SBRT) may be a less invasive alternative to brachytherapy boost. Here, we report the 3-year gastrointestinal (GI) and genitourinary (GU) toxicities of IMRT plus SBRT boost. MATERIALS AND METHODS: Between March 2008 and September 2012, patients with prostate cancer were treated with robotic SBRT (19...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28222996/stereotactic-radiation-therapy-for-residual-chemorefractory-primary-mediastinal-non-seminomatous-germ-cell-tumor-after-surgical-thoracotomy
#5
Philippe Laflamme, Cédric Doucet, Christian Sirois, Neil Kopek, Marie Vanhuyse
No abstract text is available yet for this article.
January 7, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28222111/a-meta-analysis-of-the-abscopal-effect-in-preclinical-models-is-the-biologically-effective-dose-a-relevant-physical-trigger
#6
Raffaella Marconi, Silvia Strolin, Gianluca Bossi, Lidia Strigari
BACKGROUND: Preclinical in vivo studies using small animals are considered crucial in translational cancer research and clinical implementation of novel treatments. This is of paramount relevance in radiobiology, especially for any technological developments permitted to deliver high doses in single or oligo-fractionated regimens, such as stereotactic ablative radiotherapy (SABR). In this context, clinical success in cancer treatment needs to be guaranteed, sparing normal tissue and preventing the potential spread of disease or local recurrence...
2017: PloS One
https://www.readbyqxmd.com/read/28221860/the-head-start-effect-will-acute-and-delayed-postoperative-mortality-lead-to-improved-survival-with-stereotactic-body-radiation-therapy-for-operable-stage-i-non-small-cell-lung-cancer
#7
Chad G Rusthoven, David A Palma, Suresh Senan, Brian D Kavanagh
No abstract text is available yet for this article.
February 21, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28218412/magnetic-resonance-elastography-for-prediction-of-radiation-induced-liver-disease-after-stereotactic-body-radiation-therapy
#8
Shintaro Ichikawa, Utaroh Motosugi, Mitsuhiko Oguri, Hiroshi Onishi
No abstract text is available yet for this article.
February 20, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28218383/stereotactic-ablative-radiation-therapy-as-a-potential-curative-treatment-in-duodenal-adenocarcinoma-a-case-report
#9
Francesco Maria Aquilanti, Maria Cristina Barba, Federico Bianciardi, Barbara Tolu, Barbara Nardiello, Giorgio Hamid Raza, Randa El Gawhary, Chiara D'Ambrosio, PierCarlo Gentile
PURPOSE: One of the rarest gastrointestinal neoplasm is small bowel cancer. Experience with its treatment modalities is limited. Stereotactic ablative radiation therapy (SABR) has improved, with image-guided radiation therapy becoming a curative option in many tumors. Especially when surgery cannot be performed due to comorbidities, SABR provides a good toxicity profile and an excellent tumor control rate owing to its specific schedule: high dose on a limited and well-defined area. METHODS: An 83-year-old man had arterial hypertension and congestive cardiomyopathy, with recent history of upper abdominal pain, weight loss over 10 kg, and progressive severe fatigue...
February 11, 2017: Tumori
https://www.readbyqxmd.com/read/28217873/radiosurgery-for-arteriovenous-malformations-and-the-impact-on-headaches
#10
Greg Bowden, Jonathon Cavaleri, Hideyuki Kano, Edward Monaco, Ajay Niranjan, John Flickinger, L Dade Lunsford
BACKGROUND: Arteriovenous malformations (AVMs) can underlie many diverse neurological signs and symptoms. Headaches are a common presentation that can have a significant impact on quality of life. OBJECTIVE: The authors investigated Gamma Knife(®) stereotactic radiosurgery (SRS) outcomes in patients with AVMs and associated headaches. METHODS: This retrospective study analyzed 102 patients with AVMs who underwent SRS between 1995 and 2013...
February 20, 2017: Headache
https://www.readbyqxmd.com/read/28210908/updates-in-outcomes-of-stereotactic-radiation-therapy-in-acromegaly
#11
REVIEW
Monica Livia Gheorghiu
Purpose Treatment of acromegaly has undergone important progress in the last 20 years mainly due to the development of new medical options and advances in surgical techniques. Pituitary surgery is usually first-line therapy, and medical treatment is indicated for persistent disease, while radiation (RT) is often used as third-line therapy. The benefits of RT (tumor volume control and decreased hormonal secretion) are hampered by the long latency of the effect and the high risk of adverse effects. Stereotactic RT methods have been developed with the aim to provide more precise targeting of the tumor with better control of the radiation dose received by the adjacent brain structures...
February 16, 2017: Pituitary
https://www.readbyqxmd.com/read/28203052/early-experiences-of-planning-stereotactic-radiosurgery-using-3d-printed-models-of-eyes-with-uveal-melanomas
#12
Alena Furdová, Miron Sramka, Andrej Thurzo, Adriana Furdová
OBJECTIVE: The objective of this study was to determine the use of 3D printed model of an eye with intraocular tumor for linear accelerator-based stereotactic radiosurgery. METHODS: The software for segmentation (3D Slicer) created virtual 3D model of eye globe with tumorous mass based on tissue density from computed tomography and magnetic resonance imaging data. A virtual model was then processed in the slicing software (Simplify3D(®)) and printed on 3D printer using fused deposition modeling technology...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28202227/phase-i-trial-of-radiation-therapy-and-sorafenib-in-unresectable-liver-metastases
#13
Rebecca B Goody, Anthony M Brade, Lisa Wang, Tim Craig, James Brierley, Robert Dinniwell, Rebecca K S Wong, Charles Cho, John Kim, Zahra Kassam, Jolie Ringash, Jennifer J Knox, Laura A Dawson
BACKGROUND AND PURPOSE: To determine maximum tolerated dose (MTD) and toxicities of sorafenib combined with stereotactic radiotherapy (SBRT) or whole liver radiotherapy (WLRT) in patients with liver metastases. MATERIAL AND METHODS: Eligible patients had unresectable liver metastases. Sorafenib dose was escalated in 2 strata: I - SBRT: effective liver volume irradiated (Veff)<80% (30-60Gy in 6 fractions); II - WLRT: Veff>80% (21.6Gy in 6 fractions). Four weeks of sorafenib, with radiotherapy during weeks 2-3, was delivered at 3 escalating dose levels (200-400mg twice daily)...
February 12, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28195750/dosimetric-analysis-of-neural-and-vascular-structures-in-skull-base-tumors-treated-with-stereotactic-radiosurgery
#14
Yarah M Haidar, Jay M Bhatt, Yaser Ghavami, Omid Moshtaghi, Amanda Schwer, Stafford Chenery, Hamid R Djalilian
Objective To examine the relationship between the prescribed target dose and the dose to healthy neurovascular structures in patients with vestibular schwannomas treated with stereotactic radiosurgery (SRS). Study Design Case series with chart review. Setting SRS center from 2011 to 2013. Subjects Twenty patients with vestibular schwannomas treated at the center from 2011 to 2013. Methods Twenty patients with vestibular schwannomas were included. The average radiation dose delivered to healthy neurovascular structures (eg, carotid artery, basilar artery, facial nerve, trigeminal nerve, and cochlea) was analyzed...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28195507/predicting-risk-factors-for-radiation-pneumonitis-after-stereotactic-body-radiation-therapy-for-primary-or-metastatic-lung-tumors
#15
Mitsuru Okubo, Tomohiro Itonaga, Tatsuhiko Saito, Sachika Shiraishi, Ryuji Mikami, Hidetugu Nakayama, Akira Sakurada, Shinji Sugahara, Kiyoshi Koizumi, Koichi Tokuuye
OBJECTIVES: To investigate risk factors for radiation-induced pneumonitis (RP) after hypofractionated stereotactic body radiotherapy (SBRT) in patients with lung tumors. METHODS: From May 2004 to January 2016, 66 patients with 71 primary or metastatic lung tumors were treated with SBRT; these 71 cases were retrospectively analyzed for RP. To explore the risk factors for RP, the following factors were investigated: age, sex, performance status, operability, number of treatments, respiratory gating, pulmonary emphysema, tumor location, and subclinical interstitial lung disease (ILD)...
February 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28192598/overall-survival-and-the-response-to-radiotherapy-among-molecular-subtypes-of-breast-cancer-brain-metastases-treated-with-targeted-therapies
#16
Jacob A Miller, Rupesh Kotecha, Manmeet S Ahluwalia, Alireza M Mohammadi, Samuel T Chao, Gene H Barnett, Erin S Murphy, Michael A Vogelbaum, Lilyana Angelov, David M Peereboom, John H Suh
BACKGROUND: The current study was conducted to investigate survival and the response to radiotherapy among patients with molecular subtypes of breast cancer brain metastases treated with or without targeted therapies. METHODS: Patients diagnosed with breast cancer brain metastases at a single tertiary care institution were included. The primary outcome was overall survival, whereas secondary outcomes included the cumulative incidences of distant intracranial failure, local failure, and radiation necrosis...
February 13, 2017: Cancer
https://www.readbyqxmd.com/read/28180048/stereotactic-radiation-for-palliation-of-skull-base-recurrences-of-salivary-gland-carcinomas-implications-for-tumor-targeting
#17
Zaid A Siddiqui, Edward Melian, Anil Sethi, Vikram C Prabhu, Iris Rusu, Bahman Emami, John P Leonetti, Douglas E Anderson
Background Approximately 3 to 13% of salivary carcinomas recur at the skull base. We report our experience treating these recurrences with stereotactic radiation. Methods In total, 14 patients with skull base recurrence of salivary gland carcinoma were identified. Patient characteristics, treatment parameters, response to treatment, local recurrence-free/overall survival, and patterns of failure were studied. Results All 12 symptomatic patients experienced palliation of symptoms. Two grade 3 toxicities were observed...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28178376/treatment-trends-for-patients-with-brain-metastases-does-practice-reflect-the-data
#18
Kiri A Sandler, Narek Shaverdian, Ryan R Cook, Amar U Kishan, Christopher R King, Isaac Yang, Michael L Steinberg, Percy Lee
BACKGROUND: Published guidelines regarding the optimal treatment strategies for brain metastases focus on patients with ≤3 lesions. As delivery techniques for stereotactic radiosurgery (SRS) improve, radiation oncologists are increasingly using it for patients with >3 metastases. In the current study, the authors sought to characterize practice patterns among practitioners to identify areas of controversy. METHODS: A survey of practicing radiation oncologists was distributed via e-mail...
February 8, 2017: Cancer
https://www.readbyqxmd.com/read/28175523/331%C3%A2-association-between-radiation-necrosis-and-tumor-biology-following-stereotactic-radiosurgery-for-brain-metastasis
#19
Jacob A Miller, Elizabeth Emily Bennett, Roy Xiao, Rupesh Kotecha, Samuel T Chao, Michael A Vogelbaum, Gene H Barnett, Lilyana Angelov, Erin Murphy, Jennifer Yu, Manmeet Ahluwalia, John H Suh, Alireza M Mohammadi
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28169234/salvage-stereotactic-radiosurgery-for-recurrent-glioblastoma-multiforme-with-prior-radiation-therapy
#20
Douglas E Holt, Mark E Bernard, Kimmen Quan, David A Clump, Johnathan A Engh, Steven A Burton, Dwight E Heron
BACKGROUND: Glioblastoma multiforme (GBM) carries a poor prognosis with high recurrence rates. Salvage stereotactic radiosurgery (SRS) may be an effective treatment option. METHODS: We retrospectively reviewed 34 patients (41 lesions) treated with salvage SRS for recurrent GBM between 2004 and 2012. Initial surgical treatments were gross total resection (58%), subtotal resection (STR) (24%), and biopsy (18%). All patients were treated with prior radiation therapy...
October 2016: Journal of Cancer Research and Therapeutics
keyword
keyword
43605
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"