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https://www.readbyqxmd.com/read/29153246/usefulness-of-the-american-heart-association-s-life-simple-7-to-predict-the-risk-of-atrial-fibrillation-from-the-reasons-for-geographic-and-racial-differences-in-stroke-regards-study
#1
Parveen K Garg, Wesley T O'Neal, Adedotun Ogunsua, Evan L Thacker, George Howard, Elsayed Z Soliman, Mary Cushman
The American Heart Association has identified metrics of ideal cardiovascular (CV) health known as Life's Simple 7 (LS7). We determined the prospective relationship between the LS7 and the incident atrial fibrillation (AF) in a biracial cohort. The REasons for Geographic And Racial Differences in Stroke (REGARDS) study enrolled non-Hispanic black and white adults 45 years or older. This analysis included 9,576 REGARDS participants (mean age 63 ± 8.4 years; 57% women; 30% black) who were free of AF at baseline and completed a follow-up examination 9...
October 19, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29145767/addressing-geographic-confounding-through-spatial-propensity-scores-a-study-of-racial-disparities-in-diabetes
#2
Melanie L Davis, Brian Neelon, Paul J Nietert, Kelly J Hunt, Lane F Burgette, Andrew B Lawson, Leonard E Egede
Motivated by a study exploring differences in glycemic control between non-Hispanic black and non-Hispanic white veterans with type 2 diabetes, we aim to address a type of confounding that arises in spatially referenced observational studies. Specifically, we develop a spatial doubly robust propensity score estimator to reduce bias associated with geographic confounding, which occurs when measured or unmeasured confounding factors vary by geographic location, leading to imbalanced group comparisons. We augment the doubly robust estimator with spatial random effects, which are assigned conditionally autoregressive priors to improve inferences by borrowing information across neighboring geographic regions...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/29103864/apolipoprotein-e-gene-polymorphism-and-subclinical-carotid-atherosclerosis-the-northern-manhattan-study
#3
Brett Doliner, Chuanhui Dong, Susan H Blanton, Hannah Gardener, Mitchell S V Elkind, Ralph L Sacco, Ryan T Demmer, Moise Desvarieux, Tatjana Rundek
BACKGROUND: Apolipoprotein E (APOE) polymorphism has previously been associated with carotid intima-media thickness (cIMT) in predominantly Caucasian populations. We sought to test the strength of the relationship between APOE-ε4 carrier status and subclinical atherosclerosis in a tri-ethnic population with a large Hispanic representation. METHODS: We assessed the association between APOE polymorphism and cIMT and plaque burden among 1243 stroke-free individuals (mean age 69 years, 65% Hispanic, 18% black, 17% white) using a sequence of multivariable regression models...
November 2, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29101688/racial-disparities-and-factors-affecting-michigan-colorectal-cancer-screening
#4
Vincent Grzywacz, Nasir Hussain, Neli Ragina
INTRODUCTION: The objective of this study was to investigate the various factors that influence colorectal cancer screening in Michigan using 6091 participants in the Michigan Behavioral Risk Factor Surveillance System representing adults ≥ 50 years old. METHODS: Screening for colorectal cancer was assessed as fecal occult blood testing or colonoscopy/sigmoidoscopy. Full models simultaneously adjusted for alcohol use, angina/coronary heart disease, stroke, heart attack, gender, income, marital status, race, age, diabetes, disability, exercise, health care coverage, health care access, smoking, and mental health...
November 3, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29024310/influence-of-metabolic-syndrome-and-race-on-the-relationship-between-intensive-blood-pressure-control-and-cardiovascular-outcomes-in-the-sprint-cohort
#5
Kathleen Dungan, Timothy E Craven, Kyaw Soe, Jackson T Wright, Jan Basile, William E Haley, Nancy R Kressin, Uzma Rani, Leonardo Tamariz, Jeff Whittle, Alan Wiggers, Kwame Osei
AIMS: To determine whether baseline metabolic syndrome (MetS) modifies the effect of intensive blood pressure control on cardiovascular (CV) outcomes, and whether the effects varied by race/ethnicity. METHODS: We performed post hoc analyses among non-Hispanic black, non-hispanic white and Hispanic participants, with and without MetS, in the Systolic Blood Pressure Intervention Trial (SPRINT), who were randomized to a systolic blood pressure (SBP) target of <120 mm Hg (intensive group, N = 4544) or an SBP target of <140 mm Hg (standard group, N = 4553)...
October 12, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29021359/increasing-prevalence-of-vascular-risk-factors-in-patients-with-stroke-a-call-to-action
#6
Fadar Oliver Otite, Nicholas Liaw, Priyank Khandelwal, Amer M Malik, Jose G Romano, Tatjana Rundek, Ralph L Sacco, Seemant Chaturvedi
OBJECTIVE: To evaluate trends in prevalence of cardiovascular risk factors (hypertension, diabetes, dyslipidemia, smoking, and drug abuse) and cardiovascular diseases (carotid stenosis, chronic renal failure [CRF], and coronary artery disease [CAD]) in acute ischemic stroke (AIS) in the United States. METHODS: We used the 2004-2014 National Inpatient Sample to compute weighted prevalence of each risk factor in hospitalized patients with AIS and used joinpoint regression to evaluate change in prevalence over time...
November 7, 2017: Neurology
https://www.readbyqxmd.com/read/29018136/dietary-sodium-to-potassium-ratio-and-risk-of-stroke-in-a-multiethnic-urban-population-the-northern-manhattan-study
#7
MULTICENTER STUDY
Joshua Willey, Hannah Gardener, Sandino Cespedes, Ying K Cheung, Ralph L Sacco, Mitchell S V Elkind
BACKGROUND AND PURPOSE: There is growing evidence that increased dietary sodium (Na) intake increases the risk of vascular diseases, including stroke, at least in part via an increase in blood pressure. Higher dietary potassium (K), seen with increased intake of fruits and vegetables, is associated with lower blood pressure. The goal of this study was to determine the association of a dietary Na:K with risk of stroke in a multiethnic urban population. METHODS: Stroke-free participants from the Northern Manhattan Study, a population-based cohort study of stroke incidence, were followed-up for incident stroke...
November 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28987334/cost-effectiveness-and-return-on-investment-of-a-scalable-community-weight-loss-intervention
#8
Tzeyu L Michaud, Wen You, Kathryn E Wilson, Dejun Su, Todd J McGuire, Fabio A Almeida, Amy L Bayer, Paul A Estabrooks
This study assessed the lifetime health and economic consequences of an efficacious scalable community weight loss program for overweight and obese adults. We applied a state-transition Markov model to project lifetime economic outcome (US dollar) and the degree of disease averted as a result of a weight loss intervention, compared with no intervention, from a payer perspective. Effect sizes of the intervention on weight loss, by sex, race and ethnicity, and body mass index (BMI) of participants, were derived from a 12-month community program...
December 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28985268/clinical-outcomes-by-race-and-ethnicity-in-the-systolic-blood-pressure-intervention-trial-sprint-a-randomized-clinical-trial
#9
Carolyn H Still, Carlos J Rodriguez, Jackson T Wright, Timothy E Craven, Adam P Bress, Glenn M Chertow, Paul K Whelton, Jeffrey C Whittle, Barry I Freedman, Karen C Johnson, Capri G Foy, Jiang He, John B Kostis, James P Lash, Carolyn F Pedley, Roberto Pisoni, James R Powell, Barry M Wall
BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) showed that targeting a systolic blood pressure (SBP) of ≤ 120 mm Hg (intensive treatment) reduced cardiovascular disease (CVD) events compared to SBP of ≤ 140 mm Hg (standard treatment); however, it is unclear if this effect is similar in all racial/ethnic groups. METHODS: We analyzed SPRINT data within non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic subgroups to address this question...
August 23, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28959503/stroke-quality-measures-in-mexican-americans-and-non-hispanic-whites
#10
Darin B Zahuranec, Lynda D Lisabeth, Jonggyu Baek, Eric E Adelman, Nelda M Garcia, Erin C Case, Morgan S Campbell, Lewis B Morgenstern
Mexican Americans (MAs) have been shown to have worse outcomes after stroke than non-Hispanic Whites (NHWs), but it is unknown if ethnic differences in stroke quality of care may contribute to these worse outcomes. We investigated ethnic differences in the quality of inpatient stroke care between MAs and NHWs within the population-based prospective Brain Attack Surveillance in Corpus Christi (BASIC) Project (February 2009- June 2012). Quality measures for inpatient stroke care, based on the 2008 Joint Commission Primary Stroke Center definitions were assessed from the medical record by a trained abstractor...
2017: Journal of Health Disparities Research and Practice
https://www.readbyqxmd.com/read/28951154/controversies-and-evidence-for-cardiovascular-disease-in-the-diverse-hispanic-population
#11
REVIEW
Palma M Shaw, Venita Chandra, Guillermo A Escobar, Nicholas Robbins, Vincent Rowe, Robyn Macsata
OBJECTIVE: Hispanics account for approximately 17% of the U.S. POPULATION: They are one of the fastest growing racial/ethnic groups, second only to Asians. This heterogeneous population has diverse socioeconomic conditions, making the prevention, diagnosis, and management of vascular disease difficult. This paper discusses the cultural, racial, and social aspects of the Hispanic community in the United States and assesses how they affect vascular disease within this population...
September 23, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28935697/impact-of-stroke-risk-factors-on-ethnic-stroke-disparities-among-midlife-mexican-americans-and-non-hispanic-whites
#12
Rajiv C Patel, Brisa N Sánchez, Lewis B Morgenstern, Chengwei Li, Lynda D Lisabeth
BACKGROUND AND PURPOSE: We examined the contribution of stroke risk factors to midlife (age 45-59 years) Mexican American and non-Hispanic White ischemic stroke (IS) rate disparities from 2000 to 2010. METHODS: Incident IS cases (n=707) and risk factors were identified from the Brain Attack Surveillance in Corpus Christi Project, Nueces County, TX (2000-2010). US Census data (2000-2010) were used to estimate the population at-risk for IS, and the Behavioral Risk Factor Surveillance System (2000-2010) was used to estimate risk factor prevalence in the stroke-free population...
October 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28890012/ethnicity-race-and-post-operative-stroke-risk-among-53-593-patients-with-asymptomatic-carotid-stenosis-undergoing-revascularization
#13
Roxanna M Garcia, Seungwon Yoon, Tene Cage, Matthew B Potts, Michael T Lawton
BACKGROUND: The incidence of post-operative stroke following carotid endarterectomy is an uncommon event and differences by racial and ethnic subgroups are not fully described in the literature. OBJECTIVE: To investigate the impact of race and ethnicity on post-operative stroke risk among patients with asymptomatic carotid stenosis undergoing carotid endarterectomy. METHODS: The ACS-NSQIP database between 2008 and 2015 was used to identify patients undergoing carotid endarterectomy with no stroke history...
September 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28880858/vital-signs-recent-trends-in-stroke-death-rates-united-states-2000-2015
#14
Quanhe Yang, Xin Tong, Linda Schieb, Adam Vaughan, Cathleen Gillespie, Jennifer L Wiltz, Sallyann Coleman King, Erika Odom, Robert Merritt, Yuling Hong, Mary G George
INTRODUCTION: The prominent decline in U.S. stroke death rates observed for more than 4 decades has slowed in recent years. CDC examined trends and patterns in recent stroke death rates among U.S. adults aged ≥35 years by age, sex, race/ethnicity, state, and census region. METHODS: Trends in the rates of stroke as the underlying cause of death during 2000-2015 were analyzed using data from the National Vital Statistics System. Joinpoint software was used to identify trends in stroke death rates, and the excess number of stroke deaths resulting from unfavorable changes in trends was estimated...
September 8, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28877564/intracranial-atherosclerosis-from-microscopy-to-high-resolution-magnetic-resonance-imaging
#15
REVIEW
Wen-Jie Yang, Ka-Sing Wong, Xiang-Yan Chen
Intracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of intracranial atherosclerotic disease resembles extracranial atherosclerosis, there are some notable differences in the onset and severity of atherosclerosis. Current understanding of intracranial atherosclerotic disease has been advanced by the high-resolution magnetic resonance imaging (HRMRI), a novel emerging imaging technique that can directly visualize the vessel wall pathology...
September 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28873124/trends-in-dementia-incidence-in-a-birth-cohort-analysis-of-the-einstein-aging-study
#16
Carol A Derby, Mindy J Katz, Richard B Lipton, Charles B Hall
Importance: Trends in dementia incidence rates have important implications for planning and prevention. To better understand incidence trends over time requires separation of age and cohort effects, and few prior studies have used this approach. Objectives: To examine trends in dementia incidence and concomitant trends in cardiovascular comorbidities among individuals aged 70 years or older who were enrolled in the Einstein Aging Study between 1993 and 2015. Design, Setting, and Participants: In this birth cohort analysis of all-cause dementia incidence in persons enrolled in the Einstein Aging Study from October 20, 1993, through November 17, 2015, a systematically recruited, population-based sample of 1348 participants from Bronx County, New York, who were 70 years or older without dementia at enrollment and at least one annual follow-up was studied...
November 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28845486/the-effects-of-chronic-medical-conditions-and-obesity-on-self-reported-disability-in-older-mexican-americans
#17
Sanggon Nam, Soham Al Snih, Kyriakos Markides
We investigated the effect of chronic medical conditions including obesity on self-reported disability and mobility in Mexican Americans aged 75 or over using data from the Hispanic Established Population for the Epidemiological Study of the Elderly (Hispanic EPESE) Wave 5 (2004-2005). Disability was assessed with a modified version of the Katz activities of daily living (ADL) scale and mobility was assessed with the Rosow Breslau scale of gross mobility function. The percentage of participants needing assistance with ADLs were as follows: 26...
2017: Texas Public Health Journal
https://www.readbyqxmd.com/read/28803784/race-ethnic-disparities-in-cardiometabolic-risk-profiles-among-stroke-survivors-with-undiagnosed-diabetes-and-prediabetes-in-the-united-states
#18
Okkyung Kim, Bruce Ovbiagele, Natalie Valle, Daniela Markovic, Amytis Towfighi
BACKGROUND AND PURPOSE: Up to 25% of the U.S. population has undiagnosed diabetes. Diabetes and stroke both disproportionately afflict race/ethnic minorities. We assessed race/ethnic differences in the prevalence of undiagnosed diabetes, prediabetes, and cardiometabolic risk profiles among stroke survivors in the United States. METHODS: The prevalence of diabetes and prediabetes among adults (≥20 years) with a self-reported history of stroke was assessed using the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2010...
August 10, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28796991/epidemiology-of-intracranial-and-extracranial-large-artery-stenosis-in-a-population-based-study-of-stroke-in-the-middle-east
#19
Hamidreza Saber, Amin Amiri, Amanda G Thrift, Saverio Stranges, Reza Bavarsad Shahripour, Mohammad T Farzadfard, Naghmeh Mokhber, Réza Behrouz, Mahmoud Reza Azarpazhooh
BACKGROUND: Intracranial large-artery disease (LAD) is a predominant vascular lesion found in patients with stroke of Asian, African, and Hispanic origin, whereas extracranial LAD is more prevalent among Caucasians. These patterns are not well-established in the Middle East. We aimed to characterize the incidence, risk factors, and long-term outcome of LAD strokes in a Middle-Eastern population. METHODS: The Mashhad Stroke Incidence Study is a community-based study that prospectively ascertained all cases of stroke among the 450,229 inhabitants of Mashhad, Iran between 2006 and 2007...
August 11, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28761681/smoking-intensity-and-duration-is-associated-with-cardiac-structure-and-function-the-echocardiographic-study-of-hispanics-latinos
#20
J Adam Leigh, Robert C Kaplan, Katrina Swett, Pelbreton Balfour, Mayank M Kansal, Gregory A Talavera, Krista Perreira, Michael J Blaha, Emelia J Benjamin, Rosemarie Robertson, Aruni Bhartnagar, Carlos J Rodriguez
OBJECTIVE: Cardiovascular disease is the leading cause of death in smokers and this relationship is complicated by the multiplicity of cardiovascular effects of smoking. However, the relationship between intensity and duration of cigarette smoking and echocardiographic measures of right and left ventricular structure and function has been poorly studied. METHODS: We examined ECHO-SOL (Echocardiographic Study of Hispanics/Latinos) participants, a subset of the Hispanic Community Health Study/Study of Latinos...
2017: Open Heart
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