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https://www.readbyqxmd.com/read/28471765/impact-of-aging-on-neurocognitive-performance-in-previously-antiretroviral-na%C3%A3-ve-hiv-individuals-on-their-first-suppressive-regimen
#1
Hamza Coban, Kevin Robertson, Marlene Smurzynski, Supriya Krishnan, Kunling Wu, Ronald J Bosch, Ann C Collier, Ronald J Ellis
BACKGROUND: Despite treatment with virologically suppressive antiretroviral therapy (ART), neurocognitive impairment may persist or develop de novo in aging HIV-infected individuals. We evaluated advancing age as a predictor of neurocognitive impairment in a large cohort of previously ART-naïve individuals on long-term ART DESIGN:: The AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) was a prospective cohort study of HIV-infected individuals originally enrolled in randomized ART trials...
May 3, 2017: AIDS
https://www.readbyqxmd.com/read/28467145/implementing-an-advance-care-planning-intervention-in-community-settings-with-older-latinos-a-feasibility-study
#2
Frances R Nedjat-Haiem, Iraida V Carrion, Krystyna Gonzalez, Alejandra Quintana, Kathleen Ell, Mary O'Connell, Beti Thompson, Shiraz I Mishra
BACKGROUND: Older Latinos with serious medical conditions such as cancer and other chronic diseases lack information about advance care planning (ACP). ACP Intervention (ACP-I Plan) was designed for informational and communication needs of older Latinos to improve communication and advance directives (ADs). OBJECTIVE: To determine the feasibility of implementing ACP-I Plan among seriously ill, older Latinos (≥50 years) in Southern New Mexico with one or more chronic diseases (e...
May 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28463104/characteristics-of-u-s-adults-with-hypertension-who-are-unaware-of-their-hypertension-2011-2014
#3
Ryne Paulose-Ram, Qiuping Gu, Brian Kit
Data from the National Health and Nutrition Examination Survey •In 2011-2014, 15.9% of adults with hypertension were unaware of their hypertension. This was a 46% decline since 1999-2002 (29.5%). •A higher percentage of men (19.2%) than women (12.9%) and younger (aged 18-39, 30.8%) than older (aged 60 and over, 12.5%) adults with hypertension were unaware of their condition. •A higher percentage of non-Hispanic Asian (24.7%) and Hispanic (20.2%) adults than non-Hispanic white (14.9%) and non-Hispanic black (14...
April 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28453789/serum-tumor-necrosis-factor-receptor-1-is-associated-with-trajectories-of-functional-status-the-northern-manhattan-study
#4
Mandip S Dhamoon, Ying-Kuen Cheung, Yeseon P Moon, Clinton B Wright, Joshua Z Willey, Ralph L Sacco, Mitchell S V Elkind
We hypothesized that tumor necrosis factor receptor-1 (TNFR1) levels are associated with long-term trajectories of functional status independently of vascular risk factors and stroke and myocardial infarction (MI) occurring during follow-up. In the Northern Manhattan Study, stroke-free individuals in northern Manhattan aged >40 years had annual assessments with the Barthel index (BI) for a median of 13 years. Baseline demographics, risk factors, and laboratory studies included TNFR1 (n = 1,863). Generalized estimating equation models estimated standardized associations between TNFR1 and 1) baseline functional status and 2) change in function over time, adjusting for demographics, vascular risk factors, social variables, cognition, and depression, and stroke and MI occurring during follow-up...
April 27, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28449915/high-prevalence-of-poststroke-sleep-disordered-breathing-in-mexican-americans
#5
Lynda D Lisabeth, Brisa N Sánchez, Ronald D Chervin, Lewis B Morgenstern, Darin B Zahuranec, Susan D Tower, Devin L Brown
OBJECTIVE: The purpose of this study is to compare sleep-disordered breathing (SDB) prevalence and severity after stroke between Mexican Americans (MAs) and non-Hispanic whites (NHWs). PATIENTS/METHODS: Ischemic stroke (IS) patients within ∼30 days of onset were identified from the population-based BASIC Project (2010-2014) and offered screening with an overnight cardiopulmonary monitoring device, ApneaLink Plus™. The number of apneas and hypopneas per hour, as reflected by the apnea/hypopnea index (AHI), was used to measure SDB severity; SDB was defined as AHI ≥10...
May 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28446647/relationship-between-carotid-arterial-properties-and-cerebral-white-matter-hyperintensities
#6
Tatjana Rundek, David Della-Morte, Hannah Gardener, Chuanhui Dong, Matthew S Markert, Jose Gutierrez, Eugene Roberts, Mitchell S V Elkind, Charles DeCarli, Ralph L Sacco, Clinton B Wright
OBJECTIVE: Since arterial stiffness is a functional measure of arterial compliance and may be an important marker of cerebrovascular disease, we examined the association of carotid artery stiffness with white matter hyperintensity volume (WMHV) in a cross-sectional study of 1,166 stroke-free participants. METHODS: Carotid beta stiffness index (STIFF) was assessed by M-mode ultrasound of the common carotid artery and calculated as the ratio of natural log of the difference between systolic and diastolic blood pressure over STRAIN, a ratio of the difference between carotid systolic and diastolic diameter (DD) divided by DD...
April 26, 2017: Neurology
https://www.readbyqxmd.com/read/28439183/race-ethnic-disparities-in-hospital-arrival-time-after-ischemic-stroke
#7
Mellanie V Springer, Daniel L Labovitz, Ethan C Hochheiser
OBJECTIVE: Conflicting reports exist about hospital arrival time after stroke onset in Hispanics compared with African Americans and Caucasians. Our current study investigates race-ethnic disparities in hospital arrival times after stroke onset. METHODS: We performed a retrospective analysis of hospital arrival times in Hispanic, African American, and Caucasian acute ischemic stroke patients (N=1790) presenting to a tertiary-care hospital in the Bronx, New York...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/28431619/age-sex-and-race-ethnic-temporal-trends-in-metabolic-syndrome-prevalence-among-individuals-with-myocardial-infarction-or-stroke-in-the-united-states
#8
Alain Lekoubou, Bruce Ovbiagele, Daniela Markovic, Nerses Sanossian, Amytis Towfighi
INTRODUCTION: Metabolic syndrome (MetS), an independent risk factor for myocardial infarction (MI) and stroke, affects 1 in 3 adults in the United States. Recent trends in MetS prevalence among MI and stroke survivors are unknown. METHODS: We assessed age, sex, race/ethnicity, and socio-economic status specific trends in rates of MetS among adults ≥18years who participated in National Health and Nutrition Examination Surveys 1999-2010 and who fasted for 8h (n=12,502)...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28424998/correlates-and-predictors-of-mobility-limitation-in-community-dwelling-hispanic-older-adults-in-the-united-states-a-systematic-review
#9
REVIEW
Jane Chung, Angelina Flores-Montoya
This article presents a systematic review of the literature on correlates/predictors of mobility limitation among community-dwelling U.S. Hispanic older adults. A search of scientific databases (PubMed, CINAHL, and PsycINFO) was conducted. After abstract and full text review, 20 epidemiologic studies that met all eligibility criteria were included. The theoretical framework of mobility was used to categorize factors related to mobility limitation. The majority of the studies reviewed (n = 17) examined some aspect of physical factors in relation to mobility limitation...
April 19, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28407815/acute-symptomatic-peri-lead-edema-33%C3%A2-hours-after-deep-brain-stimulation-surgery-a-case-report
#10
Nathan B Schoen, Walter J Jermakowicz, Corneliu C Luca, Jonathan R Jagid
BACKGROUND: Symptomatic peri-lead edema is a rare complication of deep brain stimulation that has been reported to develop 4 to 120 days postoperatively. CASE PRESENTATION: Here we report the case of a 63-year-old Hispanic man with an 8-year history of Parkinson's disease who underwent bilateral placement of subthalamic nucleus deep brain stimulation leads and presented with acute, symptomatic, unilateral, peri-lead edema just 33 hours after surgery. CONCLUSIONS: We document a thorough radiographic time course showing the evolution of these peri-lead changes and their regression with steroid therapy, and discuss the therapeutic implications of these findings...
April 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28403935/a-prospective-study-of-low-fasting-glucose-with-cardiovascular-disease-events-and-all-cause-mortality-the-women-s-health-initiative
#11
Morgana Mongraw-Chaffin, Andrea Z LaCroix, Dorothy D Sears, Lorena Garcia, Lawrence S Phillips, Elena Salmoirago-Blotcher, Oleg Zaslavsky, Cheryl A M Anderson
BACKGROUND: While there is increasing recognition of the risks associated with hypoglycemia in patients with diabetes, few studies have investigated incident cause-specific cardiovascular outcomes with regard to low fasting glucose in the general population. OBJECTIVE: We hypothesized that low fasting glucose would be associated with cardiovascular disease risk and all-cause mortality in postmenopausal women. METHODS: To test our hypothesis, we used both continuous incidence rates and Cox proportional hazards models in 17,287 participants from the Women's Health Initiative with fasting glucose measured at baseline...
May 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28395017/prevalence-of-cardiovascular-risk-factors-and-strokes-in-younger-adults
#12
Mary G George, Xin Tong, Barbara A Bowman
Importance: While stroke mortality rates have decreased substantially in the past 2 decades, this trend has been primarily limited to older adults. Increasing trends in stroke incidence and hospitalizations have been noted among younger adults, but there has been concern that this reflected improved diagnosis through an increased use of imaging rather than representing a real increase. Objectives: To determine whether stroke hospitalization rates have continued to increase and to identify the prevalence of associated stroke risk factors among younger adults...
April 10, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28389617/a-dedicated-spanish-language-line-increases-enrollment-of-hispanics-into-prehospital-clinical-research
#13
Nerses Sanossian, Lauren Rosenberg, David S Liebeskind, Sidney Starkman, Marc Eckstein, Samuel Stratton, Franklin D Pratt, Scott Hamilton, May Kim-Tenser, Latisha K Sharma, Lucas Restrepo, Miguel Valdes-Suieras, Robin Conwit, Jeffrey L Saver
BACKGROUND AND PURPOSE: Novel methods are needed to reduce the disparity of Hispanic enrollment in stroke clinical trials. Prehospital enrollment using a dedicated Spanish language line may help overcome this bias. METHODS: Subjects or legally authorized representatives provided information on race and ethnicity for all cases enrolled in the FAST-MAG clinical trial (Field Administration of Stroke Therapy-Magnesium), a prehospital phase 3 randomized study of intravenous magnesium for neuroprotection...
May 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28386042/mexican-americans-receive-less-intensive-stroke-rehabilitation-than-non-hispanic-whites
#14
Lewis B Morgenstern, Emma Sais, Michael Fuentes, Nneka L Ifejika, Xiaqing Jiang, Susan D Horn, Erin Case, Lynda D Lisabeth
BACKGROUND AND PURPOSE: Mexican Americans (MAs) have worse neurological, functional, and cognitive outcomes after stroke. Stroke rehabilitation is important for good outcome. In a population-based study, we sought to determine whether allocation of stroke rehabilitation services differed by ethnicity. METHODS: Patients with stroke were identified as part of the Brain Attack Surveillance in Corpus Christi (BASIC) project, TX, USA. Cases were validated by physicians using source documentation...
June 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28363729/independent-correlates-of-chronic-kidney-disease-awareness-among-adults-with-type-2-diabetes
#15
Ndidiamaka O Obadan, Rebekah J Walker, Leonard E Egede
BACKGROUND: Chronic Kidney Disease (CKD) is usually silent until advanced stages. Awareness of CKD is important to mitigate poorer outcomes. This study aims to understand the relationship(s) between CKD self-awareness and diagnosed CKD. METHODS: The study included 345 adults with type 2 diabetes from two primary care settings. Participants completed surveys assessing demographic information, self-care behaviors and co-morbidities. Biological data were taken from medical records...
June 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28341719/brain-perivascular-spaces-as-biomarkers-of-vascular-risk-results-from-the-northern-manhattan-study
#16
J Gutierrez, M S V Elkind, C Dong, M Di Tullio, T Rundek, R L Sacco, C B Wright
BACKGROUND AND PURPOSE: Dilated perivascular spaces in the brain are associated with greater arterial pulsatility. We hypothesized that perivascular spaces identify individuals at higher risk for systemic and cerebral vascular events. MATERIALS AND METHODS: Stroke-free participants in the population-based Northern Manhattan Study had brain MR imaging performed and were followed for myocardial infarction, any stroke, and death. Imaging analyses distinguished perivascular spaces from lesions presumably ischemic...
May 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28284206/racial-ethnic-differences-in-fall-prevalence-among-older-women-a-cross-sectional-survey-study
#17
Yifan Geng, Joan C Lo, Leslea Brickner, Nancy P Gordon
BACKGROUND: Falls are the leading cause of hip fracture in older women, with important public health implications. Fall risk increases with age and other clinical factors, and varies by race/ethnicity. International studies suggest that fall risk is lower in Asians, although data are limited in U.S. POPULATIONS: This study examines racial/ethnic differences in fall prevalence among older U.S. women within a large integrated healthcare delivery system. METHODS: This cross-sectional study used data from 6277 women ages 65-90 who responded to the 2008 or 2011 Kaiser Permanente Northern California Member Health Survey (KPNC-MHS)...
March 11, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28267855/association-between-dietary-factors-and-mortality-from-heart-disease-stroke-and-type-2-diabetes-in-the-united-states
#18
Renata Micha, Jose L Peñalvo, Frederick Cudhea, Fumiaki Imamura, Colin D Rehm, Dariush Mozaffarian
Importance: In the United States, national associations of individual dietary factors with specific cardiometabolic diseases are not well established. Objective: To estimate associations of intake of 10 specific dietary factors with mortality due to heart disease, stroke, and type 2 diabetes (cardiometabolic mortality) among US adults. Design, Setting, and Participants: A comparative risk assessment model incorporated data and corresponding uncertainty on population demographics and dietary habits from National Health and Nutrition Examination Surveys (1999-2002: n = 8104; 2009-2012: n = 8516); estimated associations of diet and disease from meta-analyses of prospective studies and clinical trials with validity analyses to assess potential bias; and estimated disease-specific national mortality from the National Center for Health Statistics...
March 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28267479/left-ventricular-mass-geometry-and-silent-cerebrovascular-disease-the-cardiovascular-abnormalities-and-brain-lesions-cabl-study
#19
Koki Nakanishi, Zhezhen Jin, Shunichi Homma, Mitchell S V Elkind, Tatjana Rundek, Aylin Tugcu, Mitsuhiro Yoshita, Charles DeCarli, Clinton B Wright, Ralph L Sacco, Marco R Di Tullio
BACKGROUND: Although abnormal left ventricular geometric patterns have prognostic value for morbidity and mortality, their possible association with silent cerebrovascular disease has not been extensively evaluated. METHODS: We examined 665 participants in the CABL study who underwent transthoracic echocardiography and brain magnetic resonance imaging. Participants were divided into 4 geometric patterns: normal geometry (n=397), concentric remodeling (n=89), eccentric hypertrophy (n=126), and concentric hypertrophy (n=53)...
March 2017: American Heart Journal
https://www.readbyqxmd.com/read/28239781/validation-of-the-promis-%C3%A2-measures-of-self-efficacy-for-managing-chronic-conditions
#20
Ann L Gruber-Baldini, Craig Velozo, Sergio Romero, Lisa M Shulman
PURPOSE: The Patient-Reported Outcomes Measurement Information System(®) (PROMIS(®)) was designed to develop, validate, and standardize item banks to measure key domains of physical, mental, and social health in chronic conditions. This paper reports the calibration and validation testing of the PROMIS Self-Efficacy for Managing Chronic Conditions measures. METHODS: PROMIS Self-Efficacy for Managing Chronic Conditions item banks comprise five domains, Self-Efficacy for Managing: Daily Activities, Symptoms, Medications and Treatments, Emotions, and Social Interactions...
February 26, 2017: Quality of Life Research
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