Christiaan Hendrik Bas van Niftrik, Martina Sebök, Patrick Nicholson, Leonardo Olijnyk, Patrick Thurner, Lashmi Venkatraghavan, Joanna Schaafsma, Ivan Radovanovic, Joseph A Fisher, Timo Krings, Zsolt Kulcsár, Michael Tymianski, Luca Regli, David J Mikulis, Jorn Fierstra
BACKGROUND: Prior Infarcts, Reactivity, and Angiography in Moyamoya Disease (PIRAMD) is a recently proposed imaging-based scoring system that incorporates the severity of disease and its impact on parenchymal hemodynamics in order to better support clinical management and evaluate response to intervention. In particular, PIRAMD may have merit in identifying symptomatic patients that may benefit most from revascularization. Our aim was to validate the PIRAMD scoring system. METHODS: Patients with ischemic Moyamoya disease, who underwent catheter angiographic [modified Suzuki Score (mSS) and collateralization status], morphological MRI and a parenchymal hemodynamic evaluation with blood oxygenation-level dependent cerebrovascular reactivity (BOLD-CVR) at two transatlantic centers, were retrospectively included...
July 1, 2023: Quantitative Imaging in Medicine and Surgery