keyword
MENU ▼
Read by QxMD icon Read
search

taiji

keyword
https://www.readbyqxmd.com/read/29210010/management-of-diabetic-macular-edema-in-japan-a-review-and-expert-opinion
#1
REVIEW
Hiroko Terasaki, Yuichiro Ogura, Shigehiko Kitano, Taiji Sakamoto, Toshinori Murata, Akito Hirakata, Tatsuro Ishibashi
Diabetic retinopathy is a frequent cause of visual impairment in working-age adults (≥ 30 years) and in Japan is most commonly observed in those aged 50-69 years. Diabetic macular edema (DME) is one of the main causes of vision disturbance in diabetic retinopathy, which is a clinically significant microvascular complication of diabetes. Anti-vascular endothelial growth factor (VEGF) therapy is becoming the mainstay of treatment for DME. However, to achieve sustained long-term improvement in visual acuity, conventional laser photocoagulation, vitrectomy and steroid therapy are also expected to play a role in the treatment of DME...
December 5, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29195110/brachial-artery-diameter-as-a-marker-for-cardiovascular-risk-assessment-fmd-j-study
#2
Tatsuya Maruhashi, Junko Soga, Noritaka Fujimura, Naomi Idei, Shinsuke Mikami, Yumiko Iwamoto, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Haruki Hashimoto, Yoshiki Aibara, Farina Mohamad Yusoff, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Ayumu Nakashima, Chikara Goto, Hirofumi Tomiyama, Bonpei Takase, Takahide Kohro, Toru Suzuki, Tomoko Ishizu, Shinichiro Ueda, Tsutomu Yamazaki, Tomoo Furumoto, Kazuomi Kario, Teruo Inoue, Shinji Koba, Kentaro Watanabe, Yasuhiko Takemoto, Takuzo Hano, Masataka Sata, Yutaka Ishibashi, Koichi Node, Koji Maemura, Yusuke Ohya, Taiji Furukawa, Hiroshi Ito, Hisao Ikeda, Akira Yamashina, Yukihito Higashi
BACKGROUND AND AIMS: Baseline brachial artery (BBA) diameter has been reported to be a potential confounding factor of flow-mediated vasodilation (FMD). The purpose of this study was to evaluate the relationships between BBA diameter and cardiovascular risk factors and compare the diagnostic accuracy of BBA diameter in subjects without cardiovascular risk factors and patients with cardiovascular disease (CVD) with that of FMD. METHODS: We measured BBA diameter and FMD in 5695 male subjects...
November 22, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29183043/benzo-e-pyrene-inhibits-endothelium-dependent-no-mediated-dilation-of-retinal-arterioles-via-superoxide-production-and-endoplasmic-reticulum-stress
#3
Takayuki Kamiya, Taiji Nagaoka, Tsuneaki Omae, Shinji Ono, Shinichi Otani, Akitoshi Yoshida
Purpose: To investigate whether benzo(e)pyrene (B(e)P), a toxicant in cigarette smoke, affects the endothelium-dependent nitric oxide (NO)-induced vasodilation of the retinal arterioles, and whether oxidative stress, distinct protein kinase signaling pathways, and endoplasmic reticulum (ER) stress are associated with the B(e)P-induced effect on the retinal arterioles. Methods: In this in vitro study, porcine retinal arterioles were isolated, cannulated, and pressurized without flow...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29179632/prediction-of-the-ablated-area-prior-to-radiofrequency-ablation-for-liver-tumor-under-ct-guidance
#4
Rika Yoshimatsu, Akinori Doi, Tomoaki Yamanishi, Miki Nishimori, Kenta Ogi, Kenji Kajiwara, Taiji Tamura, Hiroki Minamiguchi, Takuji Yamagami
PURPOSE: To evaluate the usefulness of a method we developed to predict the ablation area at the time of CT guided radiofrequency (RF) ablation for liver tumors on a CT workstation. MATERIAL AND METHODS: Ten tumors (mean diameter 15.5 mm, range, 9.0-21.5 mm) in seven patients with hepatocellular carcinoma for which CT guided RF ablation was performed were subjects of this study. After advancing the electrode, plain CT was obtained. Then a simulated ball to predict the ablated area was created on the workstation...
November 27, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29174285/longitudinal-association-among-endothelial-function-arterial-stiffness-and-subclinical-organ-damage-in-hypertension
#5
Hirofumi Tomiyama, Tomoko Ishizu, Takahide Kohro, Chisa Matsumoto, Yukihito Higashi, Bonpei Takase, Toru Suzuki, Shinichiro Ueda, Tsutomu Yamazaki, Tomoo Furumoto, Kazuomi Kario, Teruo Inoue, Shinji Koba, Yasuhiko Takemoto, Takuzo Hano, Masataka Sata, Yutaka Ishibashi, Koichi Node, Koji Maemura, Yusuke Ohya, Taiji Furukawa, Hiroshi Ito, Akira Yamashina
OBJECTIVES: To examine the longitudinal mutual association between endothelial dysfunction and arterial stiffness, and also to determine which of the two variables was more closely associated with the progression of subclinical organ damage. METHODS: The brachial-ankle pulse wave velocity (baPWV), carotid intima-media thickness (CIMT), estimated glomerular filtration rate, microalbuminuria and flow-mediated vasodilatation of the brachial artery (FMD) were measured three times at 1...
November 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29158939/mediastinal-tracheostoma-for-treatment-of-tracheostenosis-after-tracheostomy-in-a-patient-with-mucopolysaccharidosis-induced-tracheomalacia
#6
Yasuhiro Chikaishi, Kenichi Kobayashi, Shuichi Shinohara, Akihiro Taira, Yusuke Nabe, Shinji Shinohara, Taiji Kuwata, Masaru Takenaka, Soichi Oka, Ayako Hirai, Kazue Yoneda, Koji Kuroda, Naoko Imanishi, Yoshinobu Ichiki, Fumihiro Tanaka
Background: Treatment of tracheostenosis after tracheostomy in pediatric patients is often difficult. Mucopolysaccharidosis is a lysosomal storage disease that may induce obstruction of the airways. Case Presentation: A 16-year-old male patient underwent long-term follow-up after postnatal diagnosis of type II mucopolysaccharidosis. At 11 years of age, tracheostomy was performed for mucopolysaccharidosis-induced laryngeal stenosis. One week prior to presentation, he was admitted to another hospital on an emergency basis for major dyspnea...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/29145107/postoperative-thoracic-hemorrhage-after-right-upper-lobectomy-with-thoracic-wall-resection-during-rivaroxaban-anticoagulant-therapy-for-deep-leg-vein-thrombosis-a-case-report
#7
Taiji Kuwata, Masatoshi Kanayama, Ayako Hirai, Shuichi Shinohara, Masaru Takenaka, Soichi Oka, Yasuhiro Chikaishi, Naoko Imanishi, Koji Kuroda, Fumihiro Tanaka
INTRODUCTION: Postoperative pulmonary embolism (PE) is the one of the most important complications after thoracic surgery. This complicatin after the surgery is often treated by new anticoaglant drug, such as rivaroxaban, which dose not need to the monitoring of blood coaglation system. We experienced postoperative bleeding case during anticoaglant therapy using rivaroxaban. PRESENTATION OF CASE: The patient underwent a right upper lobectomy with lung and chest wall resection for lung cancer...
November 11, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29110387/cholesterol-%C3%AE-glucosyltransferase-gene-is-present-in-most-helicobacter-species-including-gastric-non-helicobacter-pylori-helicobacters-obtained-from-japanese-patients
#8
Masatomo Kawakubo, Kazuki Horiuchi, Takehisa Matsumoto, Jun Nakayama, Taiji Akamatsu, Tsutomu Katsuyama, Hiroyoshi Ota, Junji Sagara
BACKGROUND: Non-Helicobacter pylori helicobacters (NHPHs) besides H. pylori infect human stomachs and cause chronic gastritis and mucosa-associated lymphoid tissue lymphoma. Cholesteryl-α-glucosides have been identified as unique glycolipids present in H. pylori and some Helicobacter species. Cholesterol-α-glucosyltransferase (αCgT), a key enzyme for the biosynthesis of cholesteryl-α-glucosides, plays crucial roles in the pathogenicity of H. pylori. Therefore, it is important to examine αCgTs of NHPHs...
November 7, 2017: Helicobacter
https://www.readbyqxmd.com/read/29090274/a-novel-lrp1-binding-peptide-l57-that-crosses-the-blood-brain-barrier
#9
Kotaro Sakamoto, Tokuyuki Shinohara, Yusuke Adachi, Taiji Asami, Tetsuya Ohtaki
The blood-brain barrier (BBB) is a major obstacle to drug delivery into the central nervous system (CNS), in particular for macromolecules such as peptides and proteins. However, certain macromolecules can reach the CNS via a receptor-mediated transcytosis (RMT) pathway, and low-density lipoprotein receptor-related protein 1 (LRP1) is one of the promising receptors for RMT. An LRP1 ligand peptide, Angiopep-2, was reported to pass through the BBB and deliver covalently conjugated drugs into the CNS. While conjugation of LRP1 ligands with drugs would be an effective approach for drug delivery to the CNS, no other reliable LRP1 ligands have been reported to date...
December 2017: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/29070874/synergistic-acceleration-of-experimental-tooth-movement-by-supplementary-high-frequency-vibration-applied-with-a-static-force-in-rats
#10
Teruko Takano-Yamamoto, Kiyo Sasaki, Goudarzi Fatemeh, Tomohiro Fukunaga, Masahiro Seiryu, Takayoshi Daimaruya, Nobuo Takeshita, Hiroshi Kamioka, Taiji Adachi, Hiroto Ida, Atsushi Mayama
Several recent prospective clinical trials have investigated the effect of supplementary vibration applied with fixed appliances in an attempt to accelerate tooth movement and shorten the duration of orthodontic treatment. Among them, some studies reported an increase in the rate of tooth movement, but others did not. This technique is still controversial, and the underlying cellular and molecular mechanisms remain unclear. In the present study, we developed a new vibration device for a tooth movement model in rats, and investigated the efficacy and safety of the device when used with fixed appliances...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29057457/differential-effects-of-selective-agonists-of-neuromedin-u1-and-2-receptors-in-obese-and-diabetic-mice
#11
Hiroaki Nagai, Tomoko Kaisho, Kotaro Yokoyama, Tomoko Asakawa, Hisashi Fujita, Kouta Matsumiya, Jiro Noguchi, Kazue Tsuchimori, Naoki Nishizawa, Yoko Kanematsu-Yamaki, Katsuko Dote, Hiroshi Inooka, Jun-Ichi Sakamoto, Tetsuya Ohtaki, Taiji Asami, Shiro Takekawa
BACKGROUND AND PURPOSE: Neuromedin U (NMU) may be a novel target for obesity treatment owing to its anorectic and energy expenditure enhancing effects. Although two receptors, NMU1 and NMU2, are both responsible for the NMU-mediated anti-obesity effects, the receptor agonist with the most appropriate profiles for treating obesity and diabetes in terms of efficacy and safety is as yet unknown. Thus, we developed and evaluated novel NMU1/2 receptor-selective agonists. EXPERIMENTAL APPROACH: Efficacy and safety were assessed in mice with diet-induced obesity (DIO) and those with leptin-deficient diabetes (ob/ob) through repeated peripheral administration of selective agonists to NMU1 (NMU-6102) and NMU2 (NMU-2084), along with NMU1/2 non-selective agonists (NMU-0002 and NMU-6014)...
October 22, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29056945/comparison-of-the-low-density-lipoprotein-cholesterol-target-value-and-the-preventive-effect-of-statins-in-elderly-patients-and-younger-patients
#12
Akihiro Endo, Taiji Okada, Misun Pak, Yuzo Kagawa, Shimpei Ito, Hirotomo Sato, Kenji Kageshima, Yasuyuki Yoshida, Kazuaki Tanabe
OBJECTIVE: To assess whether the low-density lipoprotein cholesterol (LDL-C) target value and preventive effect of statins are different between elderly and younger patients. METHODS: We investigated 304 patients with previous percutaneous coronary intervention who underwent coronary angiography from January 2007 to December 2016 for examination of recurrent ischemia beyond the early restenosis. Patients were classified into two groups: age ≥ 75 years (elderly group: n = 140) and < 75 years (younger group: n = 164)...
June 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29048073/effective-mode-field-diameter-for-few-mode-fibers-for-considering-splice-loss-characteristics
#13
Takashi Matsui, Kazuhide Nakajima, Taiji Sakamoto
We experimentally and numerically investigate the applicability of the conventional near-field pattern, far-field pattern (FFP), and variable aperture (VA) methods for measuring the effective mode-field diameter (MFD) of the higher-order modes, which can be used for accurately evaluating splice loss. We confirmed that the variation in the MFD values obtained with the FFP and VA methods can be converged by considering the minimum scanning angle and the minimum aperture angle, respectively, for both fundamental and higher-order modes...
September 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29037032/substituent-effect-on-intramolecular-charge-transfer-of-symmetric-methoxy-substituted-bi-1-3-4-oxadiazole-derivatives
#14
Fangyi Chen, Wanxi Zhang, Taiji Tian, Binglian Bai, Haitao Wang, Min Li
Intramolecular charge-transfer characteristics of a series symmetric methoxy -substituted bi-1,3,4-oxadiazole derivatives with various substituted positions and quantities have been studied with a combination of experimental techniques and theoretical calculations to investigate the substituent effect. Different degrees of fluorescence red shift in polar solvents are observed in these compounds. The meta-substituted molecule (BOXD-m-OCH3) exhibits a larger red shift (82 nm) than the other two monosubstituted molecules, BOXD-o-OCH3 (40 nm) and BOXD-p-OCH3 (37 nm); the polysubstituted molecules BOXD-D1 and BOXD-T1 show 80 and 104 nm red shifts, respectively, which are obviously larger than the monosubstituted molecules...
October 30, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29027020/analysis-of-ca-2-response-of-osteocyte-network-by-three-dimensional-time-lapse-imaging-in-living-bone
#15
Tomoyo Tanaka, Mitsuhiro Hoshijima, Junko Sunaga, Takashi Nishida, Mana Hashimoto, Naoya Odagaki, Ryuta Osumi, Taiji Aadachi, Hiroshi Kamioka
Osteocytes form a three-dimensional (3D) cellular network within the mineralized bone matrix. The cellular network has important roles in mechanosensation and mechanotransduction related to bone homeostasis. We visualized the embedded osteocyte network in chick calvariae and observed the flow-induced Ca(2+) signaling in osteocytes using 3D time-lapse imaging. In response to the flow, intracellular Ca(2+) ([Ca(2+)]i) significantly increased in developmentally mature osteocytes in comparison with young osteocytes in the bone matrix...
October 12, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29023585/correlations-between-local-peripapillary-choroidal-thickness-and-axial-length-optic-disc-tilt-and-papillo-macular-position-in-young-healthy-eyes
#16
Takehiro Yamashita, Taiji Sakamoto, Naoya Yoshihara, Hiroto Terasaki, Minoru Tanaka, Yuya Kii, Kumiko Nakao
Optical coherence tomography (OCT) has made it possible for clinicians to measure the peripapillary choroidal thickness (ppCT) noninvasively in various ocular diseases. However, the ocular factors associated with the ppCT have not been conclusively determined. The purpose of this study was to determine the relationship between the local ppCT and the axial length, optic disc tilt, and the angle of the papillo-macular position (PMP) in healthy eyes. This was a prospective, observational cross-sectional study of 119 right eyes of 119 healthy Japanese volunteers...
2017: PloS One
https://www.readbyqxmd.com/read/28993578/characterizations-of-oral-microbiota-in-elderly-nursing-home-residents-with-diabetes
#17
Taiji Ogawa, Mariko Honda-Ogawa, Kazunori Ikebe, Yumiko Notomi, Yoshiko Iwamoto, Itsuki Shirobayashi, Seiko Hata, Masahito Kibi, Shizuko Masayasu, Satoshi Sasaki, Shigetada Kawabata, Yoshinobu Maeda
Over 700 bacterial species have been detected in the oral cavity. Several studies have suggested that periodontitis is associated with systemic disorders such as diabetes mellitus, indicating a key role for oral microbiota in human health. However, the relationship between oral microbiota and diabetes has not been well clarified. Therefore, we conducted microbiome analysis of saliva samples obtained from 15 elderly residents (3 with type 2 diabetes mellitus [DM] and 12 without diabetes [non-DM]) at three different nursing homes, as well as 9 young healthy controls (HC)...
October 6, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28992095/the-reduction-of-heparan-sulphate-in-the-glomerular-basement-membrane-does-not-augment-urinary-albumin-excretion
#18
Satoshi Aoki, Akiko Saito-Hakoda, Takeo Yoshikawa, Kyoko Shimizu, Kiyomi Kisu, Susumu Suzuki, Kiyoshi Takagi, Shuji Mizumoto, Shuhei Yamada, Toin H van Kuppevelt, Atsushi Yokoyama, Taiji Matsusaka, Hiroshi Sato, Sadayoshi Ito, Akira Sugawara
Background: Heparan sulphate proteoglycan (HSPG) is present in the glomerular basement membrane (GBM) and is thought to play a major role in the glomerular charge barrier. Reductions and structural alterations of HSPG are observed in different types of kidney diseases accompanied by proteinuria. However, their causal relations remain unknown. Methods: We generated podocyte-specific exostosin-like 3 gene ( Extl3 ) knockout mice ( Extl3KO ) using a Cre-loxP recombination approach...
July 8, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28991715/clinical-and-pathological-findings-in-familial-amyloid-polyneuropathy-caused-by-a-transthyretin-e61k-mutation
#19
Tatsufumi Murakami, Hirotake Nishimura, Taiji Nagai, Shoji Hemmi, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada
Familial amyloid polyneuropathy (FAP) is an autosomal dominant hereditary systemic amyloidosis caused by mutation of the transthyretin (TTR) gene, and usually shows sensory-dominant polyneuropathy and autonomic neuropathy at the initial stage. The pathogenesis of this neuropathy remains unknown, although several mechanisms, including mechanical compression, vessel occlusion, TTR toxicity and Schwann cell dysfunction have been proposed. We describe a patient with late-onset FAP caused by a TTR E61K mutation...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28984741/foveal-retinal-neovascularization-in-proliferative-diabetic-retinopathy-assessment-by-optical-coherence-tomography-angiography
#20
Sakura Murakawa, Taiji Hasegawa, Hideki Koizumi, Ichiro Maruko, Tomohiro Iida
No abstract text is available yet for this article.
November 2017: Retina
keyword
keyword
43585
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"