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Intracerebral pressure

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https://www.readbyqxmd.com/read/27927936/blood-pressure-levels-and-the-risk-of-intracerebral-hemorrhage-after-ischemic-stroke
#1
Nina A Hilkens, Jacoba P Greving, Ale Algra, Catharina J M Klijn
OBJECTIVE: To investigate the association between blood pressure (BP) levels and risk of intracerebral hemorrhage (ICH) after ischemic stroke. METHODS: We performed a post hoc analysis of data from the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial, a randomized clinical trial including 20,332 patients with recent noncardioembolic ischemic stroke. BP measurements were divided into predefined categories. We calculated incidence rates per BP category and performed multivariable Cox regression analysis with systolic blood pressure (SBP) and diastolic blood pressure (DBP) categories as time-dependent covariables...
December 7, 2016: Neurology
https://www.readbyqxmd.com/read/27919055/associations-with-health-related-quality-of-life-after-intracerebral-haemorrhage-pooled-analysis-of-interact-studies
#2
Candice Delcourt, Danni Zheng, Xiaoying Chen, Maree Hackett, Hisatomi Arima, Jun Hata, Emma Heeley, Rustam Al-Shahi Salman, Mark Woodward, Yining Huang, Thompson Robinson, Pablo M Lavados, Richard I Lindley, Christian Stapf, Leo Davies, John Chalmers, Craig S Anderson, Shoichiro Sato
BACKGROUND AND PURPOSE: Limited data exist on health-related quality of life (HRQoL) after intracerebral haemorrhage (ICH). We aimed to determine baseline factors associated with HRQoL among participants of the pilot and main phases of the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT 1 and 2). METHODS: The INTERACT studies were randomised controlled trials of early intensive blood pressure (BP) lowering in patients with ICH (<6 hours) and elevated systolic BP (150-220 mm Hg)...
October 21, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27907969/neuroprotection-in-critical-care-neurology
#3
Menno R Germans, Hieronymus D Boogaarts, R Loch Macdonald
Ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and traumatic brain injury-all have in common early brain injury due to brain tissue destruction, reduced cerebral blood flow and oxygen delivery, and overall substantial morbidity and mortality. The pathophysiology of brain tissue damage likely includes common cellular mechanisms. Neuroprotection has seldom, if ever, been shown to reduce early brain injury. Secondary brain injury develops after these conditions due to macroscopic events such as increased intracranial pressure and reduced cerebral blood flow, as well as cellular processes including vascular damage, inflammation, and apoptotic/necrotic cell death...
December 2016: Seminars in Neurology
https://www.readbyqxmd.com/read/27907957/surgical-strategies-for-spontaneous-intracerebral-hemorrhage
#4
Wendy Ziai, J Ricardo Carhuapoma, Paul Nyquist, Daniel F Hanley
In recent decades, the medical and surgical treatment of intracerebral hemorrhage (ICH) have become the focus of a number of scientific investigations. This effort has been led by an international group of neurologists and neurosurgeons with the goal of studying functional recovery and developing new medical and surgical treatments to facilitate improved clinical outcomes. Currently, two of the most pressing ICH investigational goals are (1) early blood pressure control, and (2) safe hematoma volume reduction...
December 2016: Seminars in Neurology
https://www.readbyqxmd.com/read/27906426/continuous-monitoring-of-intracranial-pressure-for-prediction-of-postoperative-complications-of-hypertensive-intracerebral-hemorrhage
#5
S-X Yu, Q-S Zhang, Y Yin, Z Liu, J-M Wu, M-X Yang
OBJECTIVE: This study evaluates the value of continuous dynamic monitoring of intracranial pressure (ICP) in patients with hypertensive intracerebral hemorrhage to predict early postoperative complications. PATIENTS AND METHODS: Data from 80 patients treated in our hospital from February 2014 to February 2015 were analyzed. The patients all underwent decompressive craniectomies, and their ICP changes were monitored invasively and continuously for 1 to 7 days after surgery...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27902622/efficacy-and-safety-of-penetration-acupuncture-on-head-for-acute-intracerebral-hemorrhage-a-randomized-controlled-study
#6
Hai-Qiao Wang, Chun-Ling Bao, Zhi-Hua Jiao, Gui-Rong Dong
BACKGROUND: Acupuncture, especially acupuncture treatment on head for acute intracerebral hemorrhage (ICH), has long been disputable. The aim of this study was to evaluate the efficacy and safety of penetration acupuncture on head in patients with acute ICH. METHODS: Eighty-two patients with acute ICH were randomized to receive penetration acupuncture treatment on head combined with conventional treatment (treatment group [TG]) or conventional treatment only (control group [CG])...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27899759/perioperative-antihypertensive-treatment-in-patients-with-spontaneous-intracerebral-hemorrhage
#7
Jun Zheng, Hao Li, Sen Lin, Junpeng Ma, Rui Guo, Lu Ma, Yuan Fang, Meng Tian, Ming Liu, Chao You
BACKGROUND: Studies on antihypertensive treatment for surgical patients with spontaneous intracerebral hemorrhage are insufficient. This pilot study was conducted to investigate the safety of the perioperative intensive blood pressure lowering in surgical patients with spontaneous intracerebral hemorrhage. METHODS: This study was a prospective, parallel, randomized, assessor-blinded trial. Patients allocated to the intensive group received perioperative intensive antihypertensive treatment aiming to achieve a target systolic blood pressure between 120 and 140 mm Hg, whereas the patients in the conservative group received conservative treatment aiming to achieve a target systolic blood pressure between 140 and 180 mm Hg for 7 days...
November 29, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27895301/acute-blood-pressure-management-in-intracerebral-hemorrhage-equipoise-resists-an-attack
#8
Kenneth Butcher, Magdy Selim
No abstract text is available yet for this article.
December 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27857926/intracerebral-hemorrhagic-infarction-after-cranioplasty-in-a-patient-with-sinking-skin-flap-syndrome
#9
Jai-Hyuck Han, Mou-Seop Lee
The sinking skin flap syndrome (SSFS) is a rare complication after a large craniectomy. Hemorrhage infarction after a cranioplasty is a very rare complication with only 4 cases to date. We report a case of the patient who underwent an autologous cranioplasty to treat SSFS that developed intracerebral hemorrhage infarction. A 20-year-old male was admitted to our emergency department with stuporous mentality. Emergent decompressive craniectomy (DC) have done. He had suffered from SSFS and fever of unknown origin (FUO) since DC...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27855610/a-review-on-injury-mechanism-of-intracerebral-hemorrhage-in-vehicle-accidents
#10
Fan Li, Honggeng Li, Zhi Xiao, Ronggui Lu, Zhiteng Zhang, Haiyun Zhu, Lihai Ren
BACKGROUND: Intracerebral hemorrhage is one of the most common injuries in vehicle accidents. The aim of this paper is to survey the injury mechanism of intracerebral hemorrhage in vehicle accidents, including contusion, subarachnoid hemorrhage (SAH), subdural hematoma (SDH) and diffuse axonal injury (DAI). METHODS: A condensed overview is given based on the published studies in biomechanical studies on intracerebral hemorrhage. Animal tests, cadaver tests, accident investigations and numerical simulation are the main method used for the mechanism studies...
November 18, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27847269/intrasylvian-intracerebral-hematomas-associated-with-ruptured-mca-aneurysms-a-single-center-series-and-a-review-of-literature
#11
Yupeng Zhang, Quan Hu, Hao Xue, Mingran Zhang, Jie Shen, Lin Deing, Qinglin Liu, Gang Li
OBJECTIVE: Ruptured MCA aneurysms usually lead to SAH,and several cases will represent concomitant intrasylvian or intracerebral hematomas. The objective of this paper was to compare the clinical and radiographic characteristics with their different outcomes. METHODS: The charts of 30 consecutive patients with ruptured MCA aneurysm related intracranial hematoma were retrospectively reviewed. These patients were dichotomized into ISH group and ICH group by the presence of intrahematomal contrast enhancing vessel (IHCEV), and for patients under open surgery, hematoma type was further confirmed by intraoperative observation...
November 12, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27833798/alterations-to-the-middle-cerebral-artery-of-the-hypertensive-arthritic-rat-model-potentiates-intracerebral-hemorrhage
#12
Amy Randell, Killol Chokshi, Brittany Kane, Hilary Chang, Safaa Naiel, Jeffrey G Dickhout, Noriko Daneshtalab
AIMS: We have recently created an age-dependent hypertensive-mono-arthritic animal model from the stroke-resistant spontaneously hypertensive rat to model populations with autoimmune disease who are hypertensive and are prone to stroke. The model exhibits signs of hemorrhagic stroke (HS) subsequent to chronic inflammation and hypertension. HS is also associated with the inability of middle cerebral arteries to undergo pressure dependent constriction (PDC). We investigated alterations in the cerebrovasculature of our hypertensive mono-arthritic animals that develop stroke...
2016: PeerJ
https://www.readbyqxmd.com/read/27831492/withdrawal-of-active-treatment-after-intracerebral-haemorrhage-in-the-interact2-study
#13
Paula Muñoz Venturelli, Xia Wang, Darin B Zahuranec, Pablo M Lavados, Christian Stapf, Richard Lindley, Candice Delcourt, John Chalmers, Craig S Anderson, Thompson G Robinson, Thompson G Robinson
BACKGROUND: in the second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT2), a minority of patients received withdrawal of active treatment (WAT). We wished to determine the characteristics of these patients, and the relation of this decision-making to subsequent management and final outcome. METHODS: the INTERACT2 cohort of acute intracerebral haemorrhage (ICH) patients had a decision of WAT within 7 days after hospital admission recorded...
November 9, 2016: Age and Ageing
https://www.readbyqxmd.com/read/27826284/targeting-secondary-hematoma-expansion-in-spontaneous-intracerebral-hemorrhage-state-of-the-art
#14
REVIEW
Jian Guan, Gregory W J Hawryluk
Spontaneous intracerebral hemorrhage (SICH), defined broadly as intracerebral hemorrhage not related to trauma, results in long-term disability or death in a large proportion of afflicted patients. Current management of this disease is predominantly supportive, including airway protection, optimization of hemodynamic parameters, and management of intracranial pressure. No active treatments that demonstrate beneficial effects on clinical outcome are currently available. Animal models of SICH have allowed for the elucidation of multiple pathways that may be attractive therapeutic targets...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/27824680/angiotensin-ii-receptor-blockers-following-intravenous-nicardipine-administration-to-lower-blood-pressure-in-patients-with-hypertensive-intracerebral-hemorrhage-a-prospective-randomized-study
#15
Joji Inamasu, Shunsuke Nakae, Kazuhide Adachi, Yuichi Hirose
BACKGROUND AND OBJECTIVE: In patients with hypertensive intracerebral hemorrhage (HICH), intravenous nicardipine is primarily used to lower blood pressure (BP). However, there are few studies investigating the role of oral antihypertensives administered after intravenous nicardipine to prevent BP from rising. Angiotensin II receptor blockers (ARBs) may be beneficial in HICH patients not only as antihypertensives but also by lowering plasma catecholamine levels. A prospective randomized study was conducted between January 2015 and March 2016 to comparatively evaluate the efficacy of two ARBs (azilsartan vs...
November 7, 2016: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/27816340/management-of-spontaneous-intracerebral-haemorrhages
#16
Barbara Casolla, Romain Tortuyaux, Charlotte Cordonnier
Spontaneous intracerebral haemorrhage is defined as a collection of blood in the cerebral parenchyma that is not caused by trauma. It represents roughly 10-20% of all strokes. The clinical presentation is unspecific and the diagnosis requires brain imaging. ICH is a medical emergency and ICH patients have to be admitted in an acute stroke unit. The priority is to fight against ICH expansion. The first step consists in the administration of a specific antagonist of the antithrombotic treatment when available, and in the strict control of blood pressure...
December 2016: La Presse Médicale
https://www.readbyqxmd.com/read/27808065/intensive-lowering-of-blood-pressure-in-acute-intracerebral-haemorrhage-where-do-we-stand-today
#17
M V Padma Srivastava
No abstract text is available yet for this article.
May 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/27801766/cessation-of-smoking-and-alcohol-addiction-following-thalamic-hemorrhage
#18
Fatima Najeeb, Brian Silver, Muhib Khan
INTRODUCTION: We describe a case of thalamic intracerebral hemorrhage leading to cessation of smoking. CASE REPORT: A 53-year-old female presented to the emergency department with right-sided weakness and dysarthria. Initial systolic blood pressure was 220 mm Hg. Computed tomography scan showed a left thalamic hemorrhage with associated edema and hemorrhage extending into the left lateral and third ventricle. She recovered uneventfully and was discharged to inpatient rehabilitation and eventually transitioned home...
November 2016: Neurologist
https://www.readbyqxmd.com/read/27799036/the-underestimated-role-of-mechanical-stimuli-in-brain-diseases-and-the-related-in-vitro-models
#19
Tingwang Guo, Peng Ren, Shilei Hao, Bochu Wang
BACKGROUND: Besides the well-documented biochemical and electrophysiological effects, the mechanical stimuli also have prominent roles in the initiation and development of brain diseases but yet have been underestimated. To explore the role of mechanical stimuli and the followed mechanical-biochemical effects in the brain diseases. METHOD: In this review, we discussed the initiation and effect of mechanical stimuli and the surrounding topography in brain diseases, especially for the intracerebral hemorrhage (ICH), Alzheimer's disease (AD), diffuse axonal injury (DAI) and primary brain tumors...
October 27, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27770194/-imaging-of-the-lamina-cribrosa-for-early-detection-of-glaucoma-latest-trends-from-the-annual-arvo-meeting-2016
#20
J Matlach, N Pfeiffer, V Prokosch-Willing
Studying the lamina cribrosa (LC) is relevant to understand the mechanisms of retinal ganglion cell degeneration in glaucoma and develop new diagnostic and therapeutic strategies. We would like to present some of the emerging trends and hot topics in imaging of the lamina cribrosa in glaucoma from the 2016 ARVO (The Association of Research in Vision and Ophthalmology) annual meeting, which was held in Seattle, WA, USA. Presentation of the path of ganglion cells through the pores of the lamina cribrosa as well as changes to the shape of the lamina cribrosa with increase of the intraocular and intracerebral pressure have been of great international interest...
October 21, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
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