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Intracerebral pressure

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https://www.readbyqxmd.com/read/29683540/blood-pressure-levels-in-the-acute-phase-after-intracerebral-haemorrhage-are-associated-with-mortality-in-young-adults
#1
Satu Mustanoja, Jukka Putaala, Riku-Jaakko Koivunen, Ida Surakka, Turgut Tatlisumak
BACKGROUND: Blood pressure (BP) levels in acute Intracerebral haemorrhage (ICH) and mortality have not been thoroughly studied in the young. METHODS: The relationship between BP and mortality was assessed in consecutive first-ever, non-traumatic acute ICH patients ≤50 years of age, enrolled in the Helsinki ICH Young Study. BP parameters included systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (SBP-DBP) at admission and 24 hours, and delta (admission-24 hour) BP parameters...
April 23, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29682058/hemispheric-infarct-following-a-cerebellar-hematoma-a-rare-coincidence
#2
R Girish Menon, Vinod Kumar, I K Laskhman, Rajesh P Nair
Concomitant cerebral infarction developing soon after a parenchymal intracerebral hemorrhage is a rare occurrence. Usually, these remote site changes follow tumor decompression and are associated with hemorrhagic changes rather than infarcts. We report a case of a fatal malignant internal carotid territory infarct in a hospitalized patient being conservatively managed for a vermian hematoma and discuss the probable pathophysiology. Stroke physicians need to be aware that spontaneous intracerebral hematoma patients have a potential threat of developing large vessel occlusion with malignant cerebral infarcts, especially after surgical decompression...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29648985/feasibility-of-telemetric-intracranial-pressure-monitoring-in-the-neuro-intensive-care-unit
#3
Alexander Lilja-Cyron, Jesper Kelsen, Morten Andresen, Kåre Fugleholm, Marianne Juhler
Intracranial pressure (ICP) monitoring is crucial in the management of acute neurosurgical conditions such as traumatic brain injury (TBI). However, pathological ICP may persist beyond the admission to the neuro intensive care unit (NICU). We investigated the feasibility of telemetric ICP monitoring in the NICU, as this technology provides the possibility of long-term ICP assessment beyond NICU discharge. In this prospective investigation, we implanted telemetric ICP sensors (Raumedic Neurovent-P-tel) instead of conventional, cabled ICP sensors in patients undergoing decompressive craniectomy...
March 16, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29643709/delayed-formation-of-hematomas-with-ethanol-preconditioning-in-experimental-intracerebral-hemorrhage-rats
#4
Hung-Yu Cheng, Li-Chuan Huang, Hsiao-Fen Peng, Jon-Son Kuo, Hock-Kean Liew, Cheng-Yoong Pang
Objective: Spontaneous intracerebral hemorrhage (ICH) accounts for 10%-15% of all strokes and causes high mortality and morbidity. In the previous study, we demonstrated that ethanol could aggravate the severity of brain injury after ICH by increasing neuroinflammation and oxidative stress. In this study, we further investigate the acute effects of ethanol on brain injury within 24 h after ICH. Materials and Methods: Totally, 66 male Sprague-Dawley rats were assigned randomly into two groups: saline pretreatment before ICH (saline + ICH), and ethanol pretreatment before ICH (ethanol + ICH)...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29607570/incidence-and-etiology-of-microinfarcts-in-patients-with-ischemic-stroke
#5
Jamary Oliveira-Filho, Hakan Ay, Ashkan Shoamanesh, Kwang Yeol Park, Ross Avery, Mine Sorgun, Gyeong-Moon Kim, Pedro T Cougo, Steven M Greenberg, M Edip Gurol
BACKGROUND AND PURPOSE: Cerebral microinfarcts (CMI) are associated with intracerebral hemorrhage due to small vessel disease (SVD) in studies not including an ischemic etiologic workup. We aimed to determine their incidence and potential causes in a large ischemic stroke (IS) cohort. METHODS: Consecutive patients with MRI-confirmed IS within 72 hours of onset were enrolled. Subjects had either single high-risk embolic source (cardioembolic or large vessel disease) or no embolic source...
April 1, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29603497/hypertension-and-the-acute-phase-of-intracerebral-haemorrhage-more-evidence-of-the-silent-killer
#6
Adrià Arboix
The article by Mustanoja et al. [1] published in the current issue of European Journal of Neurology is an important piece in the growing body of evidence supporting the myriad of potential life-threatening effects of uncontrolled high blood pressure. Based on patients enrolled in the Helsinki Young Acute Intracerebral Haemorrhage (ICH) Study, this study shows for the first time that in young patients (≤ 50 years) with ICH, the presence of hypertension (systolic blood pressure of 160 mm Hg or higher) on admission to the hospital was an independent predictor of death, both in the short- and long-term...
March 30, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29593024/feasibility-of-improving-cerebral-autoregulation-in-acute-intracerebral-haemorrhage-breathe-ich-study-a-protocol-for-an-experimental-interventional-study
#7
Jatinder S Minhas, Ronney B Panerai, Thompson G Robinson
INTRODUCTION: Cerebral autoregulation (CA) is impaired in a multitude of neurological conditions. Increasingly, clinical studies are correlating the nature of this impairment with prognostic markers. In acute intracerebral haemorrhage (ICH), impairment of CA has been associated with worsening clinical outcomes including poorer Glasgow Coma Score and larger haematoma volume. Hypocapnia has been shown to improve CA despite concerns over hypoperfusion and consequent ischaemic risks, and it is therefore hypothesised that hypocapnia (via hyperventilation) in acute ICH may improve CA and consequently clinical outcome...
March 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29590559/decreased-prefrontal-oxygenation-elicited-by-stimulation-of-limb-mechanosensitive-afferents-during-cycling-exercise
#8
Ryota Asahara, Kanji Matsukawa
Our laboratory reported using near-infrared spectroscopy that feedback from limb mechanoafferents may decrease prefrontal oxygenated-hemoglobin concentration (Oxy-Hb) during the late period of voluntary and passive cycling. To test the hypothesis that the decreased Oxy-Hb of the prefrontal cortex would be augmented depending on the extent of limb mechanoafferent input, the prefrontal Oxy-Hb response was measured during motor-driven one- and two-legged passive cycling for 1 min at various revolutions of pedal movement in 19 subjects...
March 28, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29577862/increased-arterial-stiffness-is-associated-with-poor-collaterals-in-acute-ischemic-stroke-from-large-vessel-occlusion
#9
Maurizio Acampa, Daniele Giuseppe Romano, Pietro Enea Lazzerini, Sara Leonini, Francesca Guideri, Rossana Tassi, Tommaso Casseri, Sandra Bracco, Giuseppe Martini
BACKGROUND: Cerebral collateral circulation is a network of arterial anastomotic channels capable of providing supplementary perfusion to brain regions in response to ischemic insults. Arterial stiffness could negatively affect collateral circulation development, by means of its effects on structural intracerebral vasculature. OBJECTIVE: The aim of our study is to investigate a possible link between arterial stiffness and presence of collateral circulation in patients with acute ischemic stroke...
March 25, 2018: Current Neurovascular Research
https://www.readbyqxmd.com/read/29556806/cerebral-hyperperfusion-syndrome-after-carotid-revascularization-and-acute-ischemic-stroke
#10
REVIEW
Kathryn F Kirchoff-Torres, Ekaterina Bakradze
PURPOSE OF REVIEW: Cerebral hyperperfusion syndrome (CHS) is a rare but significant complication after carotid revascularization and is increasingly recognized after acute stroke treatments. In this review, we discuss the epidemiology and pathophysiology of CHS, clinical presentation including ipsilateral headache, seizures, and focal neurological deficits, and radiographic presentation. We propose preventive therapies with emphasis on acute stroke post-thrombectomy hyperperfusion. RECENT FINDINGS: CHS was first described after carotid revascularization but is now also reported in patients with acute ischemic stroke...
March 19, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29548729/hyperbaric-oxygen-therapy-improves-survival-and-functional-outcome-of-acute-severe-intracerebral-hemorrhage
#11
Xiaowei Li, Jingze Li, Xuehui Yang, Zhaosheng Sun, Jinrong Zhang, Wangmiao Zhao, Shuzhi Dong, Cong Li, Yanqiao Ye, Jianchao Chen, Yongqian Li, Yi Xiang, Jianhui Mao, Guangjie Li, Hong Guo, Wenchao Zhang, Hao Guo, Yazhao Zhang, Mingzhe Zhang, Wanzeng Zhang, Zhanyi Xu, Baoshuai Zhao, Jianhui Wei, Gengshui Zhao, Ronghua Ma, Xiuzhi Shen, Chunyan Ge, Cunling Zheng, Shang Li, Yan Wang
BACKGROUND: Prognosis of spontaneous intracerebral hemorrhage (ICH) remains poor worldwide. AIMS OF THE STUDY: To investigate the effect and optimal protocol for hyperbaric-oxygen therapy (HBOT), and reduce incidence of upper gastrointestinal bleeding (UGIB) in ICH. METHODS: This prospective, randomized, controlled trial included 565 patients with acute severe ICH. Participants were randomly assigned to a sham-control group (Group A) and four intervention groups: Groups B and C with 2...
October 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29521287/blood-pressure-variability-and-outcome-in-patients-with-acute-nonlobar-intracerebral-hemorrhage-following-intensive-antihypertensive-treatment
#12
Jin Pyeong Jeon, Chulho Kim, Sung-Eun Kim
Background: Blood pressure (BP) variability has been associated with stroke risk. We elucidated the association between systolic BP (SBP) variation and outcomes in patients with nonlobar intracerebral hemorrhage (ICH) following intensive antihypertensive treatment upfront. Methods: We screened consecutive patients with spontaneous ICH who underwent intensive antihypertensive treatments targeting BP <140 mmHg between 2008 and 2016. SBPs were monitored hourly during the acute period (≤7 days after symptom onset) in the intensive care unit...
March 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29508265/cerebral-metabolic-changes-related-to-oxidative-metabolism-in-a-model-of-bacterial-meningitis-induced-by-lipopolysaccharide
#13
M Munk, F R Poulsen, L Larsen, C H Nordström, T H Nielsen
BACKGROUND: Cerebral mitochondrial dysfunction is prominent in the pathophysiology of severe bacterial meningitis. In the present study, we hypothesize that the metabolic changes seen after intracisternal lipopolysaccharide (LPS) injection in a piglet model of meningitis is compatible with mitochondrial dysfunction and resembles the metabolic patterns seen in patients with bacterial meningitis. METHODS: Eight pigs received LPS injection in cisterna magna, and four pigs received NaCl in cisterna magna as a control...
March 5, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29494438/admission-systolic-blood-pressure-predicts-the-number-of-blood-pressure-medications-at-discharge-in-patients-with-primary-intracerebral-hemorrhage
#14
Ayaz M Khawaja, Harn Shiue, Amelia K Boehme, Karen C Albright, Anand Venkatraman, Gyanendra Kumar, Michael J Lyerly, Angela Hays-Shapshak, Maira Mirza, Toby I Gropen, Mark R Harrigan
BACKGROUND: Control of systolic blood pressure (SBP) after primary intracerebral hemorrhage improves outcomes. Factors determining the number of blood pressure medications (BPM) required for goal SBP<160 mm Hg at discharge are unknown. We hypothesized that higher admission-SBPs require a greater number of BPM for goal discharge-SBP<160 mm Hg, and investigated factors influencing this goal. MATERIALS AND METHODS: We conducted a retrospective review of 288 patients who presented with primary intracerebral hemorrhage...
March 2018: Neurologist
https://www.readbyqxmd.com/read/29463290/transcranial-doppler-combined-with-quantitative-eeg-brain-function-monitoring-and-outcome-prediction-in-patients-with-severe-acute-intracerebral-hemorrhage
#15
Ying Chen, Weihai Xu, Lijuan Wang, Xiaoming Yin, Jie Cao, Fang Deng, Yingqi Xing, Jiachun Feng
BACKGROUND: Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related to increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) is increasingly used as an indirect measure of ICP, and quantitative EEG (QEEG) can reflect the coupling of CBF and metabolism. We aimed to combine TCD and QEEG to comprehensively assess brain function after ICH and provide prognostic diagnosis. METHODS: We prospectively enrolled patients with severe acute supratentorial (SAS)-ICH from June 2015 to December 2016...
February 20, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29455952/among-patients-with-intracerebral-hemorrhage-is-intensive-blood-pressure-decreasing-associated-with-improved-outcome
#16
EDITORIAL
Zachary T Brodrick, Rachael Freeze-Ramsey, Rawle A Seupaul
No abstract text is available yet for this article.
February 15, 2018: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29422100/the-influence-of-norepinephrine-and-phenylephrine-on-cerebral-perfusion-and-oxygenation-during-propofol-remifentanil-and-propofol-remifentanil-dexmedetomidine-anaesthesia-in-piglets
#17
Mai Louise Grandsgaard Mikkelsen, Rikard Ambrus, Rune Rasmussen, James Edward Miles, Helle Harding Poulsen, Finn Borgbjerg Moltke, Thomas Eriksen
BACKGROUND: Vasopressors are frequently used to increase blood pressure in order to ensure sufficient cerebral perfusion and oxygenation (CPO) during hypotensive periods in anaesthetized patients. Efficacy depends both on the vasopressor and anaesthetic protocol used. Propofol-remifentanil total intravenous anaesthesia (TIVA) is common in human anaesthesia, and dexmedetomidine is increasingly used as adjuvant to facilitate better haemodynamic stability and analgesia. Little is known of its interaction with vasopressors and subsequent effects on CPO...
February 8, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29408705/the-potential-long-term-neurological-improvement-of-early-hyperbaric-oxygen-therapy-on-hemorrhagic-stroke-in-the-diabetics
#18
Qian Xu, Shuang-Bo Fan, Yu-Lin Wan, Xian-Lan Liu, Liang Wang
AIMS: Although Hyperbaric oxygen therapy (HyperBOT) attract our attention successfully these days, it is still full of controversy on the treatment of acute stroke. The aim of this study is to assess the potential long-term neurological consequences and safety of using HyperBOT on intracerebral hemorrhage (ICH) in the diabetics. METHODS: In this prospective, randomized controlled trial, 79 diabetes patients suffering from acute ICH were randomized to treat for 60 minutes in a monoplace hyperbaric chamber pressurized with pure oxygen to 2...
February 3, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29397452/update-on-the-treatment-of-spontaneous-intraparenchymal-hemorrhage-medical-and-interventional-management
#19
REVIEW
Thomas J Cusack, J Ricardo Carhuapoma, Wendy C Ziai
PURPOSE OF REVIEW: Spontaneous intraparenchymal hemorrhage (IPH) is a prominent challenge faced globally by neurosurgeons, neurologists, and intensivists. Over the past few decades, basic and clinical research efforts have been undertaken with the goal of delineating biologically and evidence-based practices aimed at decreasing mortality and optimizing the likelihood of meaningful functional outcome for patients afflicted with this devastating condition. Here, the authors review the medical and surgical approaches available for the treatment of spontaneous intraparenchymal hemorrhage, identifying areas of recent progress and ongoing research to delineate the scope and scale of IPH as it is currently understood and treated...
February 3, 2018: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29389729/a-narrative-review-of-cardiovascular-abnormalities-after-spontaneous-intracerebral-hemorrhage
#20
Abhijit Lele, Viharika Lakireddy, Sergii Gorbachov, Nophanan Chaikittisilpa, Vijay Krishnamoorthy, Monica S Vavilala
BACKGROUND: The recommended cardiac workup of patients with spontaneous intracerebral hemorrhage (ICH) includes an electrocardiogram (ECG) and cardiac troponin. However, abnormalities in other cardiovascular domains may occur. We reviewed the literature to examine the spectrum of observed cardiovascular abnormalities in patients with ICH. METHODS: A narrative review of cardiovascular abnormalities in ECG, cardiac biomarkers, echocardiogram, and hemodynamic domains was conducted on patients with ICH...
January 31, 2018: Journal of Neurosurgical Anesthesiology
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