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https://www.readbyqxmd.com/read/28315592/carbon-quantum-dots-as-fluorescence-resonance-energy-transfer-sensors-for-organophosphate-pesticides-determination
#1
Xiaoli Wu, Yang Song, Xu Yan, Chengzhou Zhu, Yongqiang Ma, Dan Du, Yuehe Lin
Carbon quantum dots (CQDs) obtained from natural organics attract significant attention due to the abundance of carbon sources, varieties of heteroatom doping (such as N, S, P) and good biocompatibility of precursor. In this study, tunable fluorescence emission CQDs originated from chlorophyll were synthesized and characterized. The fluorescence emission can be effectively quenched by gold nanoparticles (Au NPs) via fluorescence resonance energy transfer (FRET). Thiocholine, which was produced from acetylthiocholine (ATC) by the hydrolysis of butyrylcholinesterase (BChE), could cause the aggregation of Au NPs and the corresponding recovery of FRET-quenched fluorescence emission...
March 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28302572/lingual-cd36-and-nutritional-status-differentially-regulate-fat-preference-in-obesity-prone-and-obesity-resistant-rats
#2
H Douglas Braymer, Hannah Zachary, Allyson L Schreiber, Stefany D Primeaux
Lingual fatty acid receptors (i.e. CD36) mediate the orosensory perception of fat/fatty acids and may contribute to the susceptibility to develop obesity. The current study tested the hypothesis that fat/fatty acid preference in obesity-prone (OP, Osborne-Mendel) and obesity-resistant (OR, S5B/Pl) rats is mediated by nutritional status and lingual CD36. To determine if nutritional status affected linoleic acid (LA) preference in OP and OR rats, rats were either fasted overnight or fed a high fat diet (60% kcal from fat)...
March 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28299388/the-combination-of-tibial-anterior-translation-and-axial-rotation-into-a-single-biomechanical-factor-improves-the-prediction-of-patient-satisfaction-over-each-factor-alone-in-patients-with-acl-reconstructed-knees
#3
Thomas P Branch, Shaun K Stinton, William C Hutton, Philippe Neyret
PURPOSE: The purpose of this study was to identify biomechanical factors, in both reconstructed and healthy knees, that correlate with patient satisfaction after ACL reconstruction. METHODS: Seventeen patients who had undergone unilateral ACL reconstruction were reviewed 9 years post-op. Patients completed subjective questionnaires and underwent manual knee laxity testing (Lachman-Trillat, KT-1000, and pivot shift) and automated laxity testing. During automated testing, both legs were rotated into external rotation and then internal rotation until peak rotational torque reached 5...
March 15, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28296816/low-dose-radiation-3d-intraoperative-imaging-how-low-can-we-go-an-o-arm-%C3%A2-ct-scan-cadaveric-study
#4
Vishal Sarwahi, Monica Payares, Stephen Wendolowski, Beverly Thornhill, Yungtai Lo, Terry D Amaral
STUDY DESIGN: Cadaveric study OBJECTIVE.: The objective was to evaluate O-Arm®'s ability at low dose settings to assess intraoperative screw placement. SUMMARY OF BACKGROUND DATA: Accurate placement of pedicle screws is crucial because of proximity to vital structures. Malposition of screws may result in significant morbidity and potential mortality. O-arm® provides real-time, intra-op imaging of patient's anatomy and provides higher accuracy in scoliosis surgeries, avoiding risk to vital structures...
March 14, 2017: Spine
https://www.readbyqxmd.com/read/28292737/in-vivo-metabolism-of-organophosphate-flame-retardants-and-distribution-of-their-main-metabolites-in-adult-zebrafish
#5
Guowei Wang, Hanyan Chen, Zhongkun Du, Jianhua Li, Zunyao Wang, Shixiang Gao
Understanding the metabolism of chemicals as well as the distribution and depuration of their main metabolites in tissues are essential for evaluating their fate and potential toxicity in vivo. Herein, we investigated the metabolism of six typical organophosphate (OP) flame retardants (tripropyl phosphate (TPRP), tri-n-butyl phosphate (TNBP), tris(2-butoxyethyl) phosphate (TBOEP), tris(2-chloroethyl) phosphate (TCEP), tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) and tri-p-cresyl phosphate (p-TCP)) in adult zebrafish in laboratory at three levels (0, 1/150 LC50 (environmentally relevant level), and 1/30 LC50 per OP analog)...
March 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28291828/retinoic-acid-exacerbates-chlorpyrifos-action-in-ensuing-adipogenic-differentiation-of-c3h10t%C3%A2-cells-in-a-gsk3%C3%AE-dependent-pathway
#6
Harkirat Singh Sandhu, A J S Bhanwer, Sanjeev Puri
The cell differentiation can be exploited as a paradigm to evaluate the effects of noxious chemicals, on human health, either alone or in combinations. In this regard, the effect of a known cell differentiation agent, retinoic acid (RA) was analyzed in the presence of a noxious chemical chlorpyrifos (CPF), an organophosphate (OP), the receptors of which have recently been localized to mesenchymal stem cells (MSCs). The observed imbalance of adipogenic to skeletal differentiation by CPF together with conundrum about adipogenic potential of RA prompted us to delineate their combinatorial effects on C3H10T½MSC-like undifferentiated cells...
2017: PloS One
https://www.readbyqxmd.com/read/28283374/outcomes-after-a-left-anterior-descending-artery-endarterectomy-in-advanced-coronary-artery-disease
#7
Charalampos Katselis, George Samanidis, Anastasia Papasotiriou, George Karatasakis, Ioannis Nenekidis, Eftichia Demerouti, Theofani Antoniou, Konstantinos Perreas
BACKGROUND: Coronary endarterectomy albeit infrequently utilized remains a pivotal treatment modality for advanced atherosclerotic heart disease. Benefits of coronary endarterectomy are explored in terms of better mid-term survival, freedom of major adverse cardiac and cerebrovascular events and improved left ventricular ejection fraction. METHODS: 50 patients with coronary artery disease including extensive diffuse LAD disease underwent a left anterior descending artery endarterectomy with coronary by-pass grafting and left internal mammary artery as conduit between 2006 and 2014...
February 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28282653/comparison-of-in-person-versus-telephone-interviews-for-early-syphilis-and-human-immunodeficiency-virus-partner-services-in-king-county-washington-2010-2014
#8
Christine L Heumann, David A Katz, Julia C Dombrowski, Amy B Bennett, Lisa E Manhart, Matthew R Golden
BACKGROUND: The relative effectiveness of in-person versus telephone interviews for human immunodeficiency virus (HIV)/sexually transmitted disease partner services (PS) is uncertain. METHODS: We compared outcomes of in-person versus telephone PS interviews for early syphilis (ES) and newly diagnosed HIV in King County, Washington from 2010 to 2014. We used multivariable Poisson regression to evaluate indices (number of partners per original patient [OP]) for partners named, notified, tested, diagnosed, and treated (ES only)...
April 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28281141/oxidative-potential-op-and-mineralogy-of-iron-ore-particulate-matter-at-the-gol-e-gohar-mining-and-industrial-facility-iran
#9
Naghmeh Soltani, Behnam Keshavarzi, Armin Sorooshian, Farid Moore, Christina Dunster, Ana Oliete Dominguez, Frank J Kelly, Prakash Dhakal, Mohamad Reza Ahmadi, Sina Asadi
Concentrations of total suspended particulate matter, particulate matter with aerodynamic diameter <2.5 μm (PM2.5), particulate matter <10 μm (PM10), and fallout dust were measured at the Iranian Gol-E-Gohar Mining and Industrial Facility. Samples were characterized in terms of mineralogy, morphology, and oxidative potential. Results show that indoor samples exceeded the 24-h PM2.5 and PM10 mass concentration limits (35 and 150 µg m(-3), respectively) set by the US National Ambient Air Quality Standards...
March 9, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28278278/dynamic-changes-of-the-respiratory-microbiota-and-its-relationship-to-fecal-and-blood-microbiota-in-healthy-young-cats
#10
Aida I Vientós-Plotts, Aaron C Ericsson, Hansjorg Rindt, Megan E Grobman, Amber Graham, Kaitlin Bishop, Leah A Cohn, Carol R Reinero
Advances in the field of metagenomics using culture-independent methods of microbial identification have allowed characterization of rich and diverse communities of bacteria in the lungs of healthy humans, mice, dogs, sheep and pigs. These data challenge the long held belief that the lungs are sterile and microbial colonization is synonymous with pathology. Studies in humans and animals demonstrate differences in the composition of airway microbiota in health versus disease suggesting respiratory dysbiosis occurs...
2017: PloS One
https://www.readbyqxmd.com/read/28273492/enhanced-ovalbumin-stability-at-oil-water-interface-by-phosphorylation-and-identification-of-phosphorylation-site-using-maldi-tof-mass-spectrometry
#11
Zhouyi Xiong, Meihu Ma
To improve the interfacial properties, a phosphorylation modification of OVA was performed through dry-heating at three different pH values (5.0, 7.0 and 9.0) in the presence of sodium tripolyphosphate. X-ray photoelectron and Raman spectroscopies confirmed that phosphate groups were successfully grafted onto the ovalbumin backbone through covalent interaction to form OP bond. Additionally, 23, 21 and 18 phosphorylation sites were identified in the OVA that had been phosphorylated at pH 5.0, 7.0 and 9.0 (P-OVA5, P-OVA7 and P-OVA9) respectively by MALDI-TOF mass spectroscopy...
February 21, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28272279/preoperative-computed-tomography-angiogram-cta-measurement-of-abdominal-muscles-is-a-valuable-risk-assessment-for-bulge-formation-after-microsurgical-abdominal-breast-reconstruction
#12
Elisabeth A Kappos, Jeff Jaskolka, Kate Butler, Anne C O'Neill, Stefan Op Hofer, Toni Zhong
BACKGROUND: A major shortcoming associated with abdominal tissue breast reconstruction is the long-term abdominal wall morbidity. Although abdominal core muscle size on computed tomography angiogram (CTA) has been correlated with morbidity following many abdominal surgeries, it has not been studied for abdominal breast reconstruction. Therefore, we evaluated the association between preoperative CTA-derived measurements of abdominal core muscles and postoperative abdominal wall morbidity after abdominal tissue breast reconstruction...
March 6, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28265717/the-importance-of-physical-function-to-people-with-osteoporosis
#13
C Kerr, C Bottomley, S Shingler, L Giangregorio, H M de Freitas, C Patel, S Randall, D T Gold
There is increasing need to understand patient outcomes in osteoporosis. This article discusses that fracture in osteoporosis can lead to a cycle of impairment, driven by complex psychosocial factors, having a profound impact on physical function/activity which accumulates over time. More information is required on how treatments impact physical function. INTRODUCTION: There is increasing need to understand patient-centred outcomes in osteoporosis (OP) clinical research and management...
March 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28263226/age-adjusted-alignment-goals-have-the-potential-to-reduce-pjk
#14
Renaud Lafage, Frank Schwab, Steve Glassman, Shay Bess, Bradley Harris, Justin Sheer, Robert Hart, Breton Line, Jensen Henry, Doug Burton, HanJo Kim, Eric Klineberg, Christopher Ames, Virginie Lafage
STUDY DESIGN: Retrospective cohort OBJECTIVE.: To explore proximal junctional kyphosis(PJK) as a function of age-adjusted surgical correction goals. SUMMARY OF BACKGROUND DATA: Recent adult spinal deformity(ASD) studies show that alignment targets are age-specific. Despite recognizing age and malalignment as PJK risk factors, no study has assessed the age-specific effects of alignment on PJK. METHODS: ASD patients with fusions to the pelvis were included and stratified into three groups: young adults(YA<40yo), middle aged(MA: 40-65yo), the elderly(ED>65yo)...
March 3, 2017: Spine
https://www.readbyqxmd.com/read/28262485/recent-visual-experience-shapes-visual-processing-in-rats-through-stimulus-specific-adaptation-and-response-enhancement
#15
Kasper Vinken, Rufin Vogels, Hans Op de Beeck
From an ecological point of view, it is generally suggested that the main goal of vision in rats and mice is navigation and (aerial) predator evasion [1-3]. The latter requires fast and accurate detection of a change in the visual environment. An outstanding question is whether there are mechanisms in the rodent visual system that would support and facilitate visual change detection. An experimental protocol frequently used to investigate change detection in humans is the oddball paradigm, in which a rare, unexpected stimulus is presented in a train of stimulus repetitions [4]...
February 26, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28260082/cancer-associated-fibroblasts-enhance-pancreatic-cancer-cell-invasion-by-remodeling-the-metabolic-conversion-mechanism
#16
Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Xijuan Cui, Hong Ji, Yiming Li, Ya'an Kang
We investigated the mechanism of cancer-associated fibroblasts (CAFs) in promoting the invasion and metastasis of pancreatic cancer cells in a non-vascular manner. We verified the original generation of isolated cultured CAFs and normal fibroblasts (NFs) based on the expression of α-SMA and vimentin, and we examined the cell glycolysis level through glucose consumption and lactate production experiments. The mRNA and protein expression of CAF glycolytic enzymes, lactate dehydrogenase and pyruvate kinase m2, were examined by RT-PCR and western blotting, respectively...
February 28, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28259810/0-01-0-05-robotic-ileal-interposition-for-radiation-inducted-ureteral-stricture-disease
#17
Adam S Baumgarten, Bhavik B Shah, Trushar Patel, Lucas R Wiegand
OBJECTIVE: To present a novel surgical concept utilizing preoperative imaging to estimate length needed for ileal segment. This enables robotic ileal interposition to be completed with only one position change during surgery. MATERIALS AND METHODS: The index patient is a 69 year old female with a history of stage 3B cervical cancer treated with chemotherapy and radiation 5 years prior to presentation. The patient subsequently developed a long segment stricture of the left ureter, which had been managed with ureteral stents...
March 1, 2017: Urology
https://www.readbyqxmd.com/read/28258020/lower-extremity-bypass-surgery-on-patients-transferred-from-other-hospitals-is-associated-with-increased-morbidity-and-mortality
#18
Faisal Aziz, Youngmin Chu, Erik B Lehman
BACKGROUND: Despite advances in endovascular surgery, lower extremity arterial bypass remains the gold standard treatment for severe, symptomatic peripheral arterial disease (PAD). Patients who are transferred to other hospitals have generally complex medical problems compared to those patients who are directly admitted from home. The purpose of this study is to identify factors associated with an interfacility transfer in patients with PAD and compare the postoperative outcomes of these patients to those who are directly admitted to the hospital...
February 28, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28243479/robotic-assisted-laparoscopic-prostatectomy-after-high-intensity-focused-ultrasound-failure
#19
Leon Telis, Seyed Behzad Jazayeri, David B Samadi
Background. Prostate cancer is the most common cancer diagnosed in men. As new focal therapies become more popular in treatment of prostate cancer, failure cases requiring salvage therapy with either surgical or other techniques are being reported. Objective. To report the options in treatment of prostate cancer after recurrence or failure of the primary treatment modality. Methods. We report a salvage robotic assisted laparoscopic radical prostatectomy (RALP) for prostate cancer recurrence following high intensity focused ultrasound treatment (HIFU) in the United States...
2017: Case Reports in Urology
https://www.readbyqxmd.com/read/28241096/the-prognostic-role-of-sex-race-and-human-papillomavirus-in-oropharyngeal-and-nonoropharyngeal-head-and-neck-squamous-cell-cancer
#20
Carole Fakhry, William H Westra, Steven J Wang, Annemieke van Zante, Yuehan Zhang, Eleni Rettig, Linda X Yin, William R Ryan, Patrick K Ha, Alicia Wentz, Wayne Koch, Jeremy D Richmon, David W Eisele, Gypsyamber D'Souza
BACKGROUND: Human papillomavirus (HPV) is a well-established prognostic marker for oropharyngeal squamous cell cancer (OPSCC). Because of the limited numbers of women and nonwhites in studies to date, sex and racial/ethnic differences in prognosis have not been well explored. In this study, survival differences were explored by the tumor HPV status among 1) patients with OPSCCs by sex and race and 2) patients with nonoropharyngeal (non-OP) head and neck squamous cell cancers (HNSCCs)...
February 27, 2017: Cancer
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