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https://www.readbyqxmd.com/read/28918594/the-association-of-knee-structural-pathology-with-pain-at-the-knee-is-modified-by-pain-at-other-sites-in-those-with-knee-osteoarthritis
#1
Feng Pan, Jing Tian, Dawn Aitken, Flavia Cicuttini, Tania Winzenberg, Graeme Jones
The objective of this study was to investigate the associations of knee structural abnormalities with different patterns of pain. A total of 891 participants (average age 63 years; range 50 to 80 years) participated in this study. Presence of pain at the neck, back, hands, shoulders, hips, knees, and feet was assessed by questionnaire. Participants were categorized as having no pain at any site (no pain), pain only at the knee (KP), pain at other sites but not the knee (OP), and pain at the knee and other sites (KOP)...
September 16, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28916899/impact-of-surgical-complications-on-the-risk-of-hepatocellular-carcinoma-recurrence-after-hepatic-resection
#2
Riccardo Pravisani, Umberto Baccarani, Miriam Isola, Gianluigi Adani, Dario Lorenzin, Giovanni Terrosu, Andrea Risaliti
Surgery-related morbidity has been identified as prognostic risk factor for tumor recurrence for several tumor types, but data regarding hepatocellular carcinoma (HCC) are limited and controversial. The aim of this study was to analyze the impact of surgical complications on the risk of HCC recurrence after hepatic resection (HR). A Retrospective study was conducted on a cohort of patients submitted to HR in a tertiary teaching hospital, between January 2006 and December 2015. 112 patients were submitted to HR during the study period...
September 15, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28914949/influence-of-flavonol-rich-excipient-food-onion-peel-and-dendropanax-morbifera-on-the-bioavailability-of-green-tea-epicatechins-in-vitro-and-in-vivo
#3
Eun-Hye Choi, Da-Yeon Lee, SuKyung Kim, Jin-Oh Chung, Jin-Kyu Choi, Kyung-Mi Joo, Hyun Woo Jeong, Jeong Kee Kim, Wan Gi Kim, Soon-Mi Shim
The impacts of onion peel (OP) and Dendropanax morbifera (DM), as excipient foods rich in flavonols, on the digestive recovery, intestinal absorption, and pharmacokinetics of GT epicatechins were studied via an in vitro digestion model system with Caco-2 cells and an in vivo study. The digestive stability of total epicatechins recovered from GT upon the addition of 2% DM was up to 1.12 times higher than that observed with OP. The combined effects of OP and DM, which were observed with 2% OP + DM in a ratio of 1 : 4 (w : w), significantly increased (by a factor of 1...
September 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28914935/optical-parametric-generation-in-orientation-patterned-gallium-phosphide
#4
Hanyu Ye, S Chaitanya Kumar, Junxiong Wei, P G Schunemann, M Ebrahim-Zadeh
We report an optical parametric generator (OPG) based on the new nonlinear material, orientation-patterned gallium phosphide (OP-GaP). Pumped by a Q-switched nanosecond Nd:YAG laser at 1064 nm with 25 kHz pulse repetition rate, the OPG can be tuned across 1721-1850 nm in the signal and 2504-2787 nm in the idler. Using a 40-mm-long crystal in single-pass configuration, we have generated a total average output power of up to ∼18  mW, with ∼5  mW of idler power at 2670 nm, for 2 W of input pump power...
September 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28887459/the-unexpected-role-of-bioaerosols-in-the-oxidative-potential-of-pm
#5
A Samake, G Uzu, J M F Martins, A Calas, E Vince, S Parat, J L Jaffrezo
Bioaerosols represent up to 15-25% of PM by mass, but there is currently no assessment of their impact on Oxidative Potential (OP), or capacity of particulate matter (PM) to produce damaging oxidative reactions in the human lungs. Here, the OP of selected bioaerosols (bacteria cells vs fungal spores) was assessed through the cell-free DTT assay. Results show that bioaerosols induce Reactive Oxygen Species (ROS) production, varying along the microorganism type, species, and concentration. Fungal spores show up to 10 times more ROS generation than bacterial cells...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886416/long-term-exposure-to-particulate-matter-no2-and-the-oxidative-potential-of-particulates-and-diabetes-prevalence-in-a-large-national-health-survey
#6
Maciej Strak, Nicole Janssen, Rob Beelen, Oliver Schmitz, Ilonca Vaartjes, Derek Karssenberg, Carolien van den Brink, Michiel L Bots, Martin Dijst, Bert Brunekreef, Gerard Hoek
BACKGROUND: The evidence from observational epidemiological studies of a link between long-term air pollution exposure and diabetes prevalence and incidence is currently mixed. Some studies found the strongest associations of diabetes with fine particles, other studies with nitrogen dioxide and some studies found no associations. OBJECTIVES: Our aim was to investigate associations between long-term exposure to multiple air pollutants and diabetes prevalence in a large national survey in the Netherlands...
September 5, 2017: Environment International
https://www.readbyqxmd.com/read/28885648/improving-registration-accuracy-during-total-hip-arthroplasty-a-cadaver-study-of-a-new-3-d-mini-optical-navigation-system
#7
Michael B Cross, Ran Schwarzkopf, Theodore T Miller, Eric A Bogner, Jeffrey M Muir, Jonathan M Vigdorchik
INTRODUCTION: Maintaining accuracy of component placement is an important step in ensuring the long-term stability of components during total hip arthroplasty (THA). Computer-assisted navigation has improved accuracy but errors associated with the registration process are known to impact the accuracy of final measurements. The purpose of this cadaver study was to determine the registration error associated with a novel mini-navigation system. METHODS: 3 board-certified orthopaedic surgeons performed 4 THA procedures each via the posterolateral approach on 6 cadavers (12 hips) using the mini-navigation tool...
September 2, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28884379/genetic-interaction-of-purinergic-p2x7-receptor-and-er-%C3%AE-polymorphisms-in-susceptibility-to-osteoporosis-in-chinese-postmenopausal-women
#8
Hui Wang, Chengxin Gong, Xingzi Liu, Shenqiang Rao, Tao Li, Luling He, Yijun Nie, Shuo Wang, Peipei Zhong, Yansong Xue, Jihong Wang, Jiani Zhao, Yuru Zhou, Lu Ding, Yunming Tu, Yuping Yang, Chaopeng Xiong, Shangdong Liang, Hong Xu
Osteoporosis (OP) is an increasing public health problem worldwide. Genetic factors are considered to be major contributors to the pathogenesis of OP. The aim of this study was to investigate the association of the purinergic P2X7 receptor (P2X7R) and estrogen receptor-α (ER-α) genes with OP risk, and the effect of the possible interaction between the two genes on predisposition to OP in Chinese postmenopausal women. A total of 596 subjects, including 350 OP patients and 246 controls, were recruited in this case-control study...
September 7, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28881527/-factors-correlated-with-height-gain-after-posterior-spinal-correction-surgery-in-lenke-1-adolescent-idiopathic-scoliosis
#9
B L Shi, L Xu, S H Mao, L L Xu, X Sun, Z Liu, J Qiao, Z Z Zhu, Y Qiu
Objective: To investigate the correlated factors of height gain (ΔSH) after posterior spinal correction surgery in Lenke 1 adolescent idiopathic scoliosis (AIS), and to propose the predictive model of ΔSH. Methods: From 2013 to 2015, a total of 150 Lenke 1 AIS patients undergoing posterior spinal correction surgery were included in the study, with the age of (14.3±2.9) years. The Cobb angle of major curve, thoracic kyphosis (TK) and lumbar lordosis (LL) were measured on both pre-op and post-op standing whole spine x-rays...
September 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28881517/-thoracoscopy-in-diagnosis-and-treatment-of-pleural-diseases-in-children
#10
M Chen, L L Zhong, H Huang, L Lin, H Y Deng, X F Ding, X Hu
Objective: To investigate the value of thoracoscopy in diagnosis and treatment of pleural diseases in children. Method: Clinical manifestations and treatment outcomes of 19 patients who had refractory pleural diseases treated with thoracosocy during May 2011 to August 2016 in Hunan Provincial People's Hospital were retrospectively analyzed. In 19 cases, 15 were male and 4 were female, with an average age of (4.8±2.0) years. Thirteen patients had left pleural lesion, while 5 patients had right lesion, and 1 had bilateral lesions...
September 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28880133/epidemiological-study-of-spinal-cord-injury-individuals-from-halfway-houses-in-shanghai-china
#11
Feng-Shui Chang, Qi Zhang, Mei Sun, Hui-Jiong Yu, Long-Jun Hu, Jing-Hua Wu, Gang Chen, Lian-Ding Xue, Jun Lu
OBJECTIVE: To describe the characteristics of spinal cord injury (SCI) individuals in Shanghai and examine their treatment and rehabilitation for traumatic and complete SCI individuals. DESIGN: Community-based secondary data analyses. SETTING: Shanghai, China. METHODS: We analyzed gender, age at injury, complications, disturbances of function, treatment, etiology, and severity of injury of SCI individuals that enrolled in "halfway houses", government-supported community co-op centers...
September 7, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28878517/comparison-of-metal-ion-levels-in-patients-with-hip-resurfacing-versus-total-hip-arthroplasty
#12
Craig W Forsthoefel, Nicholas M Brown, Mark L Barba
Mechanical wear at the articular surface and corrosive processes at modular junctions, such as the trunnion, are responsible for metal ions production. We retrospectively reviewed 64 patients who underwent THA with a metal on metal bearing surface and 34 patients with hip Resurfacing. Metal ion measurements, six-week post-op radiographs, and functional scores were included in the analysis. Cobalt ion levels were significantly elevated in THA patients, 2.95 μg/L as compared to resurfacing patients, (2.95 versus 1...
December 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28875469/a-panel-of-autoantibodies-against-neural-proteins-as-peripheral-biomarker-for-pesticide-induced-neurotoxicity
#13
Heba Allah Abd El Rahman, Mohamed Salama, Seham A Gad El-Hak, Mona A El-Harouny, Passent ElKafrawy, Mohamed B Abou-Donia
In the present study, we screened the sera of subjects chronically exposed to mixtures of pesticides (composed mainly of organophosphorus compounds (OPs) and others) and developed neurological symptoms for the presence of autoantibodies against cytoskeletal neural proteins. OPs have a well-characterized clinical profile resulting from acute cholinergic crisis. However, some of these compounds cause neuronal degeneration and demyelination known as organophosphorus compound-induced delayed neurotoxicity (OPIDN) and/or organophosphorus compound-induced chronic neurotoxicity (OPICN)...
September 5, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/28867755/successful-treatment-of-three-patients-with-organizing-pneumonia-associated-with-rheumatoid-arthritis-using-clarithromycin-and-prednisolone
#14
Masashi Ohe, Haruki Shida, Tetsuya Horita, Kenichiro Ito, Mitsuru Sugiura, Atsuo Hattori, Kenji Oku
Macrolides have anti-inflammatory effects and have been used to treat diffuse panbronchiolitis, bronchiectasis, and cystic fibrosis. Lately, several cases of cryptogenic organizing pneumonia (COP) and radiotherapy-related organizing pneumonia (OP) that were successfully treated with macrolides considering their anti-inflammatory effects were reported. We report three cases of OP associated with rheumatoid arthritis (RA) successfully treated with clarithromycin (CAM) and prednisolone (PSL). Case 1: A 70-year-old woman suffering from RA was admitted with cough and severe dyspnea...
2017: Drug Discoveries & Therapeutics
https://www.readbyqxmd.com/read/28865177/surface-topography-of-silicon-nitride-affects-antimicrobial-and-osseosintegrative-properties-of-tibial-implants-in-a-murine-model
#15
Masahiro Ishikawa, Karen L de Mesy Bentley, Bryan J McEntire, B Sonny Bal, Edward M Schwarz, Chao Xie
While silicon nitride (Si3 N4 ) is an antimicrobial and osseosintegrative orthopaedic biomaterial, the contribution of surface topography to these properties is unknown. Using a methicillin-resistant strain of Staphylococcus aureus (MSRA), this study evaluated Si3 N4 implants in vitro via scanning electron microscopy (SEM) and colony forming unit (CFU) assays, and later in an established in vivo murine tibia model of implant-associated osteomyelitis. In vitro, the "as-fired" Si3 N4 implants displayed significant reductions in adherent bacteria versus machined Si3 N4 (2...
September 2, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28862847/detection-of-an-iridium-dihydrogen-complex-a-proposed-intermediate-in-ionic-hydrogenation
#16
Jonathan M Goldberg, Karen I Goldberg, D Michael Heinekey, Samantha A Burgess, David B Lao, John C Linehan
Addition of high pressures of H2 to five-coordinate [((tBu)4)(POCOP)Ir(CO)(H)]OTf [((tBu)4)(POCOP) = κ(3)-C6H3-2,6-(OP((t)Bu)2)2] complexes results in observation of two new iridium-dihydrogen complexes. If the aryl moiety of the POCOP ligand is substituted with an electron withdrawing protonated dimethylamino group at the para position, hydrogen coordination is enhanced. Five-coordinate Ir-H complexes generated by addition of triflic acid to ((tBu)4)(POCOP)Ir(CO) species show an Ir-H (1)H NMR chemical shift dependence on the number of equivalents of acid present...
September 1, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28858182/metabolic-syndrome-and-30-day-outcomes-in-elective-lumbar-spinal-fusion
#17
Andrew S Chung, David Campbell, Robert Waldrop, Dennis Crandall
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To evaluate the effect of MetS on 30-day morbidity and mortality following elective lumbar spinal fusion SUMMARY OF BACKGROUND DATA.: Metabolic syndrome (MetS) is a variable combination of hypertension, obesity, elevated fasting plasma glucose, and dyslipidemia.MetS has been associated with an increased risk of post-operative morbidity and mortality in multiple surgical settings. To our knowledge, the effect of MetS on 30-day outcomes following elective lumbar spinal fusion has not been well studied...
August 29, 2017: Spine
https://www.readbyqxmd.com/read/28852920/the-significance-of-aryl-acylamidase-activity-of-acetylcholinesterase-in-osteoblast-differentiation-and-mineralization
#18
Raj Kumar Chinnadurai, Ponne Saravanaraman, Rathanam Boopathy
Osteoblast differentiation is an essential event in the developmental process, which is favoured by the production of extra cellular matrix proteins and various enzymes including discrete ones like acetylcholinesterase (AChE). Despite the fact that AChE facilitates osteoblast differentiation, the significance of its catalytic functions [esterase and aryl acylamidase (AAA) activities] in the process is yet to be ascertained. In this context, SaOS-2 cell line was used in the present study to implicate the catalytic activities of AChE in process of osteoblast differentiation and mineralization...
August 29, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28846637/the-preparation-of-ag-nanoparticle-and-ink-used-for-inkjet-printing-of-paper-based-conductive-patterns
#19
Lin Cao, Xiaohe Bai, Zhidan Lin, Peng Zhang, Shuling Deng, Xusheng Du, Wei Li
Ag nanoparticles were successfully prepared using a liquid reduction method with a suitable mixture reductant of polyethylene glycol (PEG) and ethylene glycol (EG). OP-10 as a dispersing agent, was used to prepare the conductive Ag ink. Ag nanoparticles with an average particle size of 40 nm were prepared while the ratio of PEG to EG was 1:2. Meanwhile, the Ag particles had a narrow size distribution and great dispersion performance. The effects of paper substrates, sintering temperature, and sintering time on the conductivity of the printed Ag ink pattern were also studied...
August 28, 2017: Materials
https://www.readbyqxmd.com/read/28841427/qualitative-and-quantitative-measurement-of-cannabinoids-in-cannabis-using-modified-hplc-dad-method
#20
Bhupendra Patel, Daniel Wene, Zhihua Tina Fan
This study presents an accurate and high throughput method for the quantitative determination of various cannabinoids in cannabis plant material using high pressure liquid chromatography (HPLC) with a diode array detector (DAD). Sample extraction and chromatographic analysis conditions for the measurement of cannabinoids in the complex cannabis plant material matrix were optimized. The Agilent Poroshell 120 SB-C18 column provided high resolution for all target analytes with a short run time (10minutes) given the core shell technology...
August 10, 2017: Journal of Pharmaceutical and Biomedical Analysis
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