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https://www.readbyqxmd.com/read/28534252/oxygen-isotope-fractionation-between-bird-bone-phosphate-and-drinking-water
#1
Romain Amiot, Delphine Angst, Serge Legendre, Eric Buffetaut, François Fourel, Jan Adolfssen, Aurore André, Ana Voica Bojar, Aurore Canoville, Abel Barral, Jean Goedert, Stanislaw Halas, Nao Kusuhashi, Ekaterina Pestchevitskaya, Kevin Rey, Aurélien Royer, Antônio Álamo Feitosa Saraiva, Bérengère Savary-Sismondini, Jean-Luc Siméon, Alexandra Touzeau, Zhonghe Zhou, Christophe Lécuyer
Oxygen isotope compositions of bone phosphate (δ(18)Op) were measured in broiler chickens reared in 21 farms worldwide characterized by contrasted latitudes and local climates. These sedentary birds were raised during an approximately 3 to 4-month period, and local precipitation was the ultimate source of their drinking water. This sampling strategy allowed the relationship to be determined between the bone phosphate δ(18)Op values (from 9.8 to 22.5‰ V-SMOW) and the local rainfall δ(18)Ow values estimated from nearby IAEA/WMO stations (from -16...
June 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28533829/clinical-analysis-of-aqueductal-stenosis-in-patients-with-hydrocephalus-in-a-kenyan-setting
#2
Loyal Poonamjeet Kaur, Nderitu Joseph Munyiri, Wekesa Vincent Dismus
INTRODUCTION: Aqueductal stenosis is the commonest cause of congenital hydrocephalus. The scope of this paper is to highlight the disease burden of hydrocephalus attributed to aqueductal stenosis which still remains unknown in our setting. METHODS: In a descriptive cross-sectional study, 258 records of patients diagnosed with hydrocephalus were analyzed after ethical approval from Kenyatta National Hospital- University of Nairobi (KNH-UON) ethics and research committee from January 2010 to May 2016...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28532856/implementation-of-a-referral-to-discharge-glycemic-control-initiative-for-reduction-of-surgical-site-infections-in-gynecologic-oncology-patients
#3
Laura Hopkins, Jennifer Brown-Broderick, James Hearn, Janine Malcolm, James Chan, Wendy Hicks-Boucher, Filomena De Sousa, Mark C Walker, Sylvain Gagné
OBJECTIVE(S): To evaluate the frequency of surgical site infections before and after implementation of a comprehensive, multidisciplinary perioperative glycemic control initiative. STUDY METHODS: As part of a CUSP (Comprehensive Unit-based Safety Program) initiative, between January 5 and December 18, 2015, we implemented comprehensive, multidisciplinary glycemic control initiative to reduce SSI rates in patients undergoing major pelvic surgery for a gynecologic malignancy ('Group II')...
May 20, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28529913/critical-care-management-and-intensive-care-unit-outcomes-following-cytoreductive-surgery-with-hyperthermic-intraperitoneal-chemotherapy
#4
Sumit Kapoor, Adel Bassily-Marcus, Rafael Alba Yunen, Parissa Tabrizian, Sabrine Semoin, Joseph Blankush, Daniel Labow, John Oropello, Anthony Manasia, Roopa Kohli-Seth
AIM: To study the early postoperative intensive care unit (ICU) management and complications in the first 2 wk of patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). METHODS: Our study is a retrospective, observational study performed at Icahn School of Medicine at Mount Sinai, quaternary care hospital in New York City. All adult patients who underwent CRS and HIPEC between January 1, 2007 and December 31, 2012 and admitted to ICU postoperatively were studied...
May 4, 2017: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28526647/clipping-versus-coiling-in-anterior-circulation-ruptured-intracranial-aneurysms-a-meta-analysis
#5
REVIEW
George Fotakopoulos, Eleni Tsianaka, Kostas Fountas, Demosthenes Makris, Michael Spyrou, Juha Hernesniemi
BACKGROUND: The treatment plan with open surgical or endovascular repair in anterior circulation ruptured intracranial aneurysms must be taken on the basis of its special characteristics OBJECTIVE: To evaluate the possible superiority on outcomes, studying operative mortality (Op-Mo), permanent neurologic deficit (PND), late mortality (La-Mo) and need for re-intervention (re-iter), after open surgical and endovascular repair in anterior circulation ruptured intracranial aneurysms. METHODS: This Meta-Analysis included articles that compared outcomes of the two methods, published in full text form (last search performed on 06 December 2016)...
May 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28526493/improving-comfort-around-dying-in-elderly-people-a-cluster-randomised-controlled-trial
#6
Kim Beernaert, Tinne Smets, Joachim Cohen, Rebecca Verhofstede, Massimo Costantini, Kim Eecloo, Nele Van Den Noortgate, Luc Deliens
BACKGROUND: Over 50% of elderly people die in acute hospital settings, where the quality of end-of-life care is often suboptimum. We aimed to assess the effectiveness of the Care Programme for the Last Days of Life (CAREFuL) at improving comfort and quality of care in the dying phase in elderly people. METHODS: We did a cluster randomised controlled trial in acute geriatric wards in ten hospitals in Flemish Region, Belgium, between Oct 1, 2012, and March 31, 2015...
May 16, 2017: Lancet
https://www.readbyqxmd.com/read/28523165/plasma-levels-of-matrix-metalloproteinase-9-in-patients-undergoing-off-pump-coronary-artery-bypass-grafting
#7
Haiqing Li, Zhize Yuan, Sen Li, Quan Qi, Jun Liu, Mi Zhou, Junfeng Cai, Anqing Chen, Zhe Wang, Xiaofeng Ye, Qiang Zhao
BACKGROUND: Matrix metalloproteinase 9 (MMP9) has recently emerged as a risk predictor in patients with cardiovascular diseases. However, little is known about the significance of increased plasma MMP9 in patients with perioperative myocardial injury. We aimed to investigate the role of MMP9 in the occurrence of myocardial injury during off-pump coronary artery bypass grafting (OPCAB). METHODS: A total of 34 consecutive patients with coronary artery diseases (CAD) were recruited in this prospective, observational study...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28516234/assessing-long-term-return-to-play-after-hip-arthroscopy-in-football-players-evaluating-risk-factors-for-good-prognosis
#8
D Barastegui, R Seijas, P Alvarez-Diaz, E Rivera, E Alentorn-Geli, G Steinbacher, X Cuscó, R Cugat
PURPOSE: Groin pain is the third most common disease in football players and has often been associated with hip pathology such as femoroacetabular impingement and labral lesions. Hip arthroscopy offers possibilities of function restoration via minimally invasive procedures. The aim of this study is to evaluate professional football player's injuries and their return to play after hip arthroscopy for FAI and labral injuries. METHODS: Patients that underwent hip arthroscopy between 2009 and 2014 were selected retrospectively...
May 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28515582/evaluation-of-mr-perfusion-abnormalities-in-organophosphorus-poisoning-and-its-correlation-with-spect
#9
K Uday Bhanu, Niranjan Khandelwal, Sameer Vyas, Paramjeet Singh, Anuj Prabhakar, B R Mittal, Ashish Bhalla
AIM: Acute organophosphate (OP) pesticide poisoning causes substantial morbidity and mortality worldwide. Many imaging modalities, such as computerized tomography (CT), magnetic resonance imaging (MRI), and single photon emission computed tomography (SPECT) of the brain, have been used for quantitative assessment of the acute brain insult caused by acute OP poisoning. Perfusion defects on SPECT in acutely poisoned patients with OPs have been described, however, MR perfusion abnormalities have not been described in the literature...
January 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28511465/digging-deeper-into-the-patello-femoral-joint-patello-femoral-composite-a-new-dimension-for-overstuffing-of-patello-femoral-joint
#10
Vikram Kishor Kandhari, Mohan M Desai, Surendar S Bava, Roshan N Wade
INTRODUCTION: Patello-femoral complications are the most common complications in postoperative Total Knee Arthroplasty (TKA) patients especially overstuffing of Patello - Femoral Joint (PFJ). So, to study the effects of overstuffing of PFJ in postoperative TKA patients we put forth a new dimension - "PATELLO - FEMORAL COMPOSITE (PFC)". This is the maximum distance between anterior cortical line of femur shaft and the anterior cortex of patella with knee in full extension. AIM: To calculate chances of overstuffing of PFJ in postoperative TKA patients and document the effect of overstuffing of PFJ on the passive knee Range of Motion (ROM) in post- op TKA patients...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510081/qt-prolongation-as-an-isolated-long-term-cardiac-manifestation-of-dichlorvos-organophosphate-poisoning-in-rats
#11
Arthur Shiyovich, Ran Matot, Sigal Elyagon, Noah Liel-Cohen, Yossi Rosman, Shai Shrot, Michael Kassirer, Amos Katz, Yoram Etzion
Organophosphates (OP) are used extensively as pesticides and as chemical weapons. Cardiotoxicity is a major concern in survivors of the acute poisoning. To characterize the delayed cardiac effects of OP, rats were poisoned by intraperitoneal administration of dichlorvos. In group I, poisoning (0.25-, 0.75-, 1.4-LD50) was followed by application of atropine and obidoxime. In group II, poisoning (0.35-, 0.5-LD50) was done without antidotes. Cardiac evaluation included electrocardiography and echocardiography 2- and 6-week post-exposure, arrhythmia susceptibility following administration of Isoproterenol (150 mcg/kg), and histological evaluation...
May 16, 2017: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/28507661/bone-marrow-aspirate-concentrate-in-combination-with-intravenous-iloprost-increases-bone-healing-in-patients-with-avascular-necrosis-of-the-femoral-head-a-matched-pair-analysis
#12
Hakan Pilge, Bernd Bittersohl, Johannes Schneppendahl, Tobias Hesper, Christoph Zilkens, Martin Ruppert, Rüdiger Krauspe, Marcus Jäger
With disease progression, avascular necrosis (AVN) of the femoral head may lead to a collapse of the articular surface. The exact pathophysiology of AVN remains unclear, although several conditions are known that can result in spontaneous cell death, leading to a reduction of trabecular bone and the development of AVN. Hip AVN treatment is stage-dependent in which two main stages of the disease can be distinguished: pre-collapse (ARCO 0-II) and post-collapse stage (ARCO III-IV, crescent sign). In the pre-collapse phase, core decompression (CD), with or without the addition of bone marrow (e...
November 17, 2016: Orthopedic Reviews
https://www.readbyqxmd.com/read/28507294/laparoscopic-versus-opengastric-surgery-for-the-treatment-of-pathological-t1n0m0-gastric-cancer-in-elderly-patients-a-matched-study
#13
Haiyan Pan, Tao Li, Zhigang Huang, Haibing Yu, Danli Kong, Yuanlin Ding, Congcong Pan, Yugang Jiang
The aim of this study was to compare the outcomes of laparoscopic surgery (LAP) and open gastric surgery (OP) in early gastric cancer patients aged ≥70 years.We conducted a retrospectively analysis among patientswith pathological T1N0M0 gastric cancer,who underwent LAP or OP between January 1, 2001 and December 31, 2008. We identified a well-balanced cohort of 2,360 patients (1180 patients in each group). LAP has been shown to offer a superior perioperative results to OP, including lower blood loss, shorter time to oral intake, walk and bowel function recovery, shorter time of hospital stay, and less blood transfusion required...
May 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28497417/purinergic-p2x7-receptor-functional-genetic-polymorphisms-are-associated-with-the-susceptibility-to-osteoporosis-in-chinese-postmenopausal-women
#14
Hong Xu, Chengxin Gong, Luling He, Shenqiang Rao, Xingzi Liu, Yijun Nie, Changle Liu, Tao Li, Lu Ding, Yunming Tu, Yuping Yang, Fangfang Hu, Yongfang Fan, Hui Wang, Shuo Wang, Chaopeng Xiong, Peipei Zhong, Lan Tang, Shangdong Liang
Osteoporosis (OP) is a major public health problem worldwide. Genetic factors are considered to be major contributors to the pathogenesis of OP. The purinergic P2X7 receptor (P2X7R) has been shown to play a role in the regulation of osteoblast and osteoclast activity and has been considered as an important candidate gene for OP. A case-control study was performed to investigate the associations of functional single nucleotide polymorphisms (SNPs) in the P2X7R gene (rs2393799, rs7958311, rs1718119, rs2230911, and rs3751143) with susceptibility to OP in 400 Chinese OP patients and 400 controls...
May 11, 2017: Purinergic Signalling
https://www.readbyqxmd.com/read/28496308/atorvastatin-a-double-weapon-in-osteoporosis-treatment-an-experimental-and-clinical-study
#15
Naglaa El-Nabarawi, Mohamed El-Wakd, Mostafa Salem
OBJECTIVE: The aim of this study was to evaluate the effect of atorvastatin on the bone formation and resorption markers in ovariectomized rats (experimental study), and to study its effect on the bone mineral density (BMD) in postmenopausal osteoporotic women (clinical study). MATERIALS AND METHODS: The study involved experimental and clinical aspects. In the experimental aspect, 42 female Wistar rats were divided into five groups: Group I (n=6; sham-operated), Group II (n=6; 1 mL of carboxymethyl cellulose [CMC] was administered orally), Group III (n=6; 20 mg/kg orally of atorvastatin was administered), Group IV (n=12; untreated ovariectomized [OVX] rats and served as a model of osteoporosis [OP]) and Group V (n=12; 20 mg/kg orally of atorvastatin was administered to ovariectomized rats)...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28495071/perioperative-and-economic-analysis-of-surgical-treatments-for-benign-prostatic-hyperplasia-a-study-of-the-french-committee-on-lut
#16
R Mathieu, S Lebdai, J N Cornu, A Benchikh, A R Azzouzi, N B Delongchamps, O Dumonceau, A Faix, M Fourmarier, O Haillot, B Lukacs, V Misrai, A de La Taille, G Robert, A Descazeaud
PURPOSE: To evaluate perioperative cost related to surgical treatments of benign prostatic obstruction (BPO): photoselective vaporization of the prostate (pvp), holmium/thullium laser enucleation (HoLEP/ThuLEP), transurethral resection of the prostate (TURP) and open prostatectomy (OP). MATERIAL AND METHODS: We retrospectively collected data from 237 patients who consecutively underwent a surgical treatment for BPH between January 2012 and June 2013 at nine institutions in France...
May 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28492124/predicting-postoperative-haemoglobin-changes-after-burn-surgery
#17
Petrus Slabber, Zane Farina, Nikki Allorto, Reitze Nils Rodseth
BACKGROUND: Burn surgery is associated with significant blood loss and fluid shifts that cause rapid haemoglobin (Hb) changes during and after surgery. Understanding the relationship between intraoperative and postoperative (day 1) Hb changes may assist in avoiding postoperative anaemia and unnecessary peri-operative blood transfusion. OBJECTIVE: To describe the Hb changes into the first day after burn surgery and to identify factors predictive of Hb changes that would guide blood transfusion decisions...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28489956/the-role-of-chlorogenic-acid-supplementation-in-anemia-and-mineral-disturbances-induced-by-4-tert-octylphenol-toxicity
#18
Khaled M M Koriem, Mahmoud S S Arbid, Nawal E Gomaa
4-tert-octylphenol (OP) is an endocrine-disrupting chemical that causes harmful effects to human health. Chlorogenic acid is the major dietary polyphenol present in various foods and beverages. The aim of the present study was to evaluate the protective role of chlorogenic acid in anemia and mineral disturbance occurring in OP toxicity in rats. Thirty-two male albino rats were divided into four equal groups (8 rats/group) as follows. The first (control) group was treated daily with an oral dose of 1 ml saline for two weeks...
May 10, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28489659/relationship-between-the-quantity-of-nerve-exposure-during-bilateral-sagittal-split-osteotomy-surgery-and-sensitive-recovery
#19
Paolo Gennaro, Maria Elisa Giovannoni, Niccolò Pini, Ikenna Valentine Aboh, Guido Gabriele, Giorgio Iannetti, Flavia Cascino
AIM AND OBJECTIVES: The purpose of this study was to evaluate how different exposures of the V3 nerves during orthognathic surgery impact neurosensory disturbances. METHODS: The study included 127 patients who underwent either bilateral sagittal split osteotomy (BSSO) or BSSO with maxillary le Fort 1. They were divided into 6 groups, identified by the quantity of V3 nerve exposure. All patients were examined in a pre-op period and again after 1, 3, 6 months post-op...
May 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28488139/optimization-of-lipase-production-by-solid-state-fermentation-of-olive-pomace-from-flask-to-laboratory-scale-packed-bed-bioreactor
#20
Felisbela Oliveira, José Manuel Salgado, Luís Abrunhosa, Noelia Pérez-Rodríguez, José M Domínguez, Armando Venâncio, Isabel Belo
Lipases are versatile catalysts with many applications and can be produced by solid-state fermentation (SSF) using agro-industrial wastes. The aim of this work was to maximize the production of Aspergillus ibericus lipase under SSF of olive pomace (OP) and wheat bran (WB), evaluating the effect on lipase production of C/N ratio, lipids, phenols, content of sugars of substrates and nitrogen source addition. Moreover, the implementation of the SSF process in a packed-bed bioreactor and the improvement of lipase extraction conditions were assessed...
May 9, 2017: Bioprocess and Biosystems Engineering
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