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Mitsuru Yagi, Hideaki Ohne, Tsunehiko Konomi, Kanehiro Fujiyoshi, Shinjiro Kaneko, Masakazu Takemitsu, Masafumi Machida, Yoshiyuki Yato, Takashi Asazuma
BACKGROUND CONTEXT: Gait patterns and their relationship to demographic and radiographic data in patients with adult spinal deformity (ASD) have not been fully documented. PURPOSE: To assess gait pattern in patients with ASD and the effect of corrective spinal surgery on gait. STUDY DESIGN/SETTING: Prospective case series. PATIENT SAMPLE: The gait patterns of 33 consecutive female with ASD (age 67.1 years; body mass index (BMI) 22...
October 17, 2016: Spine Journal: Official Journal of the North American Spine Society
John M Gatti, Sable Amstutz, Paul R Bowlin, Heidi A Stephany, J Patrick Murphy
PURPOSE: Open dismembered pyeloplasty is the preferred repair for ureteropelvic junction (UPJ) obstruction. Minimally invasive techniques have been applied to the original open approach, but no clear advantage has been shown to these technological advances. We evaluate outcomes between transperitoneal laparoscopic (LP) and open pyeloplasty (OP) in children. METHODS: All children aged 1 to 18 years with UPJ obstruction requiring operative repair were offered enrollment in the study...
October 17, 2016: Journal of Urology
Rosa-M Valls, Elisabet Llauradó, Sara Fernández-Castillejo, Francesc Puiggrós, Rosa Solà, Lluis Arola, Anna Pedret
BACKGROUND: Oligopin(ۚ) (OP) is a quantified extract from French Maritime Pine bark (FMPB) with low molecular weight procyanidins. The cardioprotective effects of OP need to be tested in human clinical intervention trials with an appropriate design. PURPOSE: The aim of the present study was to assess the effect of subchronic consumption of OP on cardiovascular disease risk factors such as lipid profile, systolic blood pressure (BP) and oxidized-Low Density Lipoprotein (ox-LDL) in stage-1-hypertensive subjects...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Dan Mo, Peishan Hsieh, Hongrong Yu, Lining Zhou, Jichun Gong, Lin Xu, Peng Liu, Gang Chen, Zhao Chen, Qiongying Deng
OBJECTIVE: To investigate the ethnic differences in osteoporosis (OP) and body composition (BC) and their relationship in the Maonan, Mulam, Hmong, and Yao minorities in China. DESIGN: A total of 860 Maonan, Mulam, Hmong, and Yao women were included in this cross-sectional study. Demographic, health history, and lifestyle information was collected using questionnaires. BC was measured through bioelectrical impedance analysis, and bone mineral density (BMD) was assessed via calcaneal quantitative ultrasound...
October 21, 2016: Ethnicity & Health
Hai-Juan Liu, Hua Yan, Jun Yan, Hao Li, Liang Chen, Li-Ren Han, Xiao-Fei Yang
Spinal cord injury (SCI) causes a significant amount of bone loss, which results in osteoporosis (OP). The neuropeptide substance P (SP) and SP receptors may play important roles in the pathogenesis of OP after SCI. To identify the roles of SP in the bone marrow mesenchymal stem cell derived osteoblasts (BMSC-OB) in SCI rats, we investigated the expression of neurokinin-1 receptors (NK1R) in BMSC-OB and the effects of SP on bone formation by development of BMSC-OB cultures. Sixty young male Sprague-Dawley rats were randomized into two groups: SHAM and SCI...
2016: PloS One
Pooria Hosseini, Jeff B Pawelek, Stacie Nguyen, George H Thompson, Suken A Shah, John M Flynn, John P Dormans, Behrooz A Akbarnia, Growing Spine Study Group
PURPOSE: Is there any relationship between lengthening intervals and rod fracture in traditional growing rod (TGR) surgery? METHODS: A multicenter EOS database was queried for patients who had: (1) dual growing rods for EOS; (2) minimum 2-year follow-up; (3) a minimum of 2 lengthenings; and (4) revision surgery due to rod fracture. Of 138 patients who met the criteria: 56 patients experienced at least one-rod fracture (RF group) and 82 patients had no rod fractures (NRF group)...
October 19, 2016: European Spine Journal
Pooria Hosseini, Colin Nnadi, Ľuboš Rehák, Martin Repko, Michael Grevitt, Ufuk Aydinli, Allen Carl, Jeff Pawelek, Dennis Crandall, Behrooz A Akbarnia
STUDY DESIGN: A prospective, nonrandomized, multicenter study. OBJECTIVES: The purpose of this study was to evaluate the amount of motion present at instrumented but unfused segments and at motion segments adjacent to the instrumentation following application of a new posterior apical short-segment correction technique for correcting adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: High-density pedicle screw instrumentation and posterior arthrodesis of all instrumented levels is the most common surgical treatment for AIS stabilization...
October 15, 2016: Spine
Helena Chang, David T Tzou, Manint Usawachintachit, Brian D Duty, Ryan S Hsi, Jonathan D Harper, Mathew D Sorensen, Marshall Stoller, Roger L Sur, Thomas Chi
<b>Objectives</b>: Registry-based clinical research in nephrolithiasis is critical to advancing quality in urinary stone disease management and ultimately reducing stone recurrence. A need exists to develop HIPAA-compliant registries comprised of integrated electronic health record (EHR) data using prospectively defined variables. An EHR-based standardized patient database - The Registry for Stones of the Kidney & Ureter (ReSKU™) was developed and herein we describe our implementation outcomes...
October 19, 2016: Journal of Endourology
Ishfaq A Sheikh, Iftikhar A Tayubi, Ejaz Ahmad, Majid A Ganaie, Osama S Bajouh, Samera F AlBasri, Ibtihal M J Abdulkarim, Mohd A Beg
Environmental contamination has been one of the major drawbacks of the industrial revolution. Several man-made chemicals are constantly released into the environment during the manufacturing process and by leaching from the industrial products. As a result, human and animal populations are exposed to these synthetic chemicals on a regular basis. Many of these chemicals have adverse effects on the physiological functions, particularly on the hormone systems in human and animals and are called endocrine disrupting chemicals (EDCs)...
October 14, 2016: Ecotoxicology and Environmental Safety
V A Nevzorova, E A Kochetkova, L G Ugai, Yu V Maistrovskaya, E A Khludeeva
AIM: To define the role of circulating biomarkers for the metabolism of collagen and intercellular substance and vascular remodeling in the development of osteoporosis (OP) in idiopathic pulmonary arterial hypertension (IPAH). MATERIAL AND METHODS: Functional hemodynamic parameters, bone mineral density (BMD) in the lumbar spine and femoral neck and the serum levels of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1), MMP-9/TIMP-1 complex, C-terminal telopeptide of collagen type 1 (CITP), and endothelin-1 (ET-1) were determined in 27 high-risk IPAH patients and 30 healthy volunteers...
2016: Terapevticheskiĭ Arkhiv
Haci Polat, Umut Gulacti
PURPOSE: To find answers to some catheter-related questions in hypospadias repair such as which type of catheter should be used, with which catheter balloon inflation volume, and when should the catheter be removed from the urethra? As catheter use and post-op retention time varies among surgeons in hypospadias repair. MATERIAL AND METHODS: Fifty-four 10 French all-silicone- and 54 latex Foley catheters were prepared and assigned to groups as senary. The catheter's balloons were inflated with 2, 3 and 5 mL of sterile water...
October 10, 2016: Urology Journal
Brenna M Flannery, Donald A Bruun, Douglas J Rowland, Christopher N Banks, Adam T Austin, David L Kukis, Yonggang Li, Byron D Ford, Daniel J Tancredi, Jill L Silverman, Simon R Cherry, Pamela J Lein
BACKGROUND: Acute intoxication with organophosphorus (OP) cholinesterase inhibitors can trigger convulsions that progress to life-threatening status epilepticus. Survivors face long-term morbidity including mild-to-severe decline in memory. It is posited that neuroinflammation plays a key role in the pathogenesis of OP-induced neuropsychiatric deficits. Rigorous testing of this hypothesis requires preclinical models that recapitulate relevant phenotypic outcomes. Here, we describe a rat model of acute intoxication with the OP diisopropylfluorophosphate (DFP) that exhibits persistent neuroinflammation and cognitive impairment...
October 12, 2016: Journal of Neuroinflammation
Uwe Altmann, Désirée Thielemann, Bernhard Strauß
There is a growing body of literature recognizing the importance of outpatient psychotherapy. Several studies investigated the efficacy of outpatient psychotherapy and aspects of the health care system under natural conditions. This paper gives an overview of studies from German speaking countries (TRANS-OP-, TK-, PAP-S- and QS-PSY-BAY-study).The results of the different studies indicate both, positive outcome of the therapies (e. g., reduction of symptoms with an average ES of 1,03; improvement of symptoms despite premature termination) as well as an economic benefit (end of treatment depending on treatment outcome and not limited by therapy sessions; extensions of psychotherapy only if patient is highly impaired and therapeutic alliance is positive; high reduction of supply costs and sick leave)...
October 2016: Psychiatrische Praxis
Pia Basaure, Fiona Peris-Sampedro, Maria Cabré, Ingrid Reverte, Maria Teresa Colomina
Cholinesterases (ChE) are common targets of organophosphate (OP) pesticides and play a critical role in the pathology of some dementias. While chlorpyrifos (CPF) remains one of the most commonly used OPs in the world, numerous investigations have reported its neurotoxic potential and highlighted behavioral disturbances upon its administration. Rivastigmine currently serves to treat Alzheimer's disease, but it may induce cholinergic overstimulation in non-demented individuals. The present investigation aimed to compare the acute and delayed effects caused by both ChE inhibitors in adult C57BL/6 male mice...
October 9, 2016: Behavioural Brain Research
Wenfeng Wang, Anne Wairimu Ndungu, Jun Wang
Occurrence and distribution of eight selected endocrine-disrupting compounds (EDCs), including estrone (E1), 17α-ethinylestradiol (EE2), 17α-estradiol (αE2), 17β-estradiol (βE2), estriol (E3), bisphenol A (BPA), 4-nonylphenol (NP), and 4-octylphenol (OP), were investigated in surface water and sediments of the Three Gorges Reservoir region (TGRR). The mean concentrations of E1, αE2, βE2, E3, EE2, BPA, NP, and OP were 10.3, 3.3, 3.7, 17.2, 7.8, 26.6, 10.8, and 32.3 ng L(-1) respectively in surface water and 2...
October 11, 2016: Archives of Environmental Contamination and Toxicology
Leslie Rinaldi, Mehdi Ouaissi, Gabriele Barabino, Anderson Loundou, Léa Clavel, Igor Sielezneff, Xavier Roblin, Jack Porcheron, Nicolas Williet, David Fuks, Brice Gayet, Jean-Marc Phelip
BACKGROUND: The efficacy and safety of treating elderly patients with colorectal cancer (CRC) is of concern. This study aimed to compare the short- and long-term outcomes of elective laparoscopic vs. open surgery to treat CRC in very elderly patients. METHODS: All patients aged >80 years and who had undergone a colectomy for CRC without metastasis between July 2005 and April 2012 were considered for inclusion. Demographic, clinical, operative, and postoperative data, plus overall and disease-free survival rates, were retrospectively collected and compared between two groups of patients that underwent an open procedure (OP group) or laparoscopy (LG)...
September 22, 2016: Digestive and Liver Disease
Sofía Otero, Gisela Kristoff
Organophosphate insecticides (OPs) continue to be an important class of agrochemicals used in modern agriculture worldwide. Even though these pesticides persist in the environment for a relatively short time, they show a high acute toxicity that may represent a serious hazard for wildlife. Sub-lethal effects on non-target species are a focus in pest management programs and should be used as biomarkers. Cholinesterases (ChEs) are the most used biomarker of OP exposure in vertebrate and invertebrate species. However, the combined monitoring of ChE and carboxylesterase (CE) activities may provide a more useful indication of exposure and effect of the organisms...
October 6, 2016: Aquatic Toxicology
Rana Al-Falaki, Francis Hughes, Reena Wadia, Christie Eastman, Elias Kontogiorgos, Samuel Low
Aims: This is an extended case series of patients treated with an Erbium, Chromium: Yttrium Scandium Gallium Garnet (Er,Cr:YSGG) laser as an adjunct to scaling for the management of intrabony defects. Materials & methods: 46 patients with 79 angular intrabony defects associated with pocket depths of >5mm, and a mean age of 53 ± 9 years presenting with chronic periodontitis were included in the analysis. All patients underwent a localized minimally invasive closed flap surgery utilizing Er,Cr:YSGG laser therapy...
June 29, 2016: Laser Therapy
Guanbai Wang, Yi Wang, Yu Guo, Dangcong Peng
To lower phosphorus concentration in Xi'an moat, four different phosphorus-locking materials, namely, calcium nitrate, sponge-iron, fly ash, and silica alumina clay, were selected in this experiment to study their effects on water quality and sediment. Results of the continuous 68-day experiment showed that calcium nitrate was the most effective for controlling phosphorus concentration in overlying and interstitial water, where the efficiency of locking phosphorus was >97 and 90 %, respectively. Meanwhile, the addition of calcium nitrate caused Fe/Al-bound phosphorus (Fe/Al-P) content in sediment declining but Ca-bound phosphorus (Ca-P) and organic phosphorus (OP) content ascending...
October 6, 2016: Environmental Science and Pollution Research International
T R W Herrmann
BACKGROUND: In the last 20 years various transurethral endoscopic enucleation techniques (EEP) have been established as a substitute for open prostatectomy (OP) and TURP. Since the 2016 update of the "EAU Guidelines on Management of Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS), including Benign Prostatic Obstruction (BPO)", Holmium laser enucleation of the prostate (HoLEP) and bipolar enucleation being summarized as anatomical enucleating techniques are proposed as first choice for the surgical management of BPO of large volume prostates...
October 6, 2016: Der Urologe. Ausg. A
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