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https://www.readbyqxmd.com/read/28430032/sociocultural-hegemony-gendered-identity-and-use-of-traditional-and-complementary-medicine-in-ghana
#1
Razak Mohammed Gyasi, Daniel Buor, Samuel Adu-Gyamfi, Prince Osei-Wusu Adjei, Padmore Adusei Amoah
This study investigated the gender differences in use of traditional and complementary medicine (TCM) in Ghana. Using an interviewer-administered questionnaire, we collected data from March to June 2013 from 324 randomly sampled adults in the Ashanti Region. The prevalence of TCM use in the prior 12 months was 86%. Females constituted the majority (61%) of TCM users. Female TCM users were more likely than male users to have had only a basic education, been traders (p ˂ .0001), and had health insurance (p ˂ ...
April 21, 2017: Women & Health
https://www.readbyqxmd.com/read/28426533/hiv-dna-content-in-different-cd4-t-cell-subsets-correlates-with-cd4-cd8-ratio-or-length-of-efficient-treatment
#2
Lara Gibellini, Simone Pecorini, Sara de Biasi, Elena Bianchini, Margherita Digaetano, Marcello Pinti, Gianluca Carnevale, Vanni Borghi, Giovanni Guaraldi, Cristina Mussini, Andrea Cossarizza, Milena Nasi
OBJECTIVES: HIV establishes a latent infection at different degrees within naïve (TN) or central (TCM) and effector memory (TEM) CD4+ T cell. Studying patients in whom HIV production was suppressed by combined antiretroviral therapy (cART), our main aim was to find which factors are related or can influence intracellular viral reservoir in different CD4+ T cell subsets. METHODS: We enrolled 32 HIV+ patients successfully treated for > 2 years, with a CD4+ T cell count > 500 cells/μL and plasma viremia undetectable from at least one year...
April 19, 2017: AIDS
https://www.readbyqxmd.com/read/28422185/improved-ganoderic-acids-production-in-ganoderma-lucidum-by-wood-decaying-components
#3
Yanru Hu, Shakeel Ahmed, Jiawei Li, Biaobiao Luo, Zengyan Gao, Qiyun Zhang, Xiaohua Li, Xuebo Hu
Ganoderma lucidum is a legendary Traditional Chinese Medicine (TCM) over a few thousands of years and one kind of its major active components are Ganoderic acids (GAs). GAs are largely produced in the mushroom primordium and fruiting body but much less in mycelium stage. However, little is known on the underlying regulatory mechanism. As a saprophytic fungus, G. lucidum solely obtains nutrients by wood decaying. Wood in general contains sophisticated chemical components with diverse structural units. To explore a strategy that extensively leads to GAs induction in the submerged liquid fermentation, all chemical components that might be possibly from the wood decaying were tested individually as GAs inducers...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28421119/influences-of-realgar-indigo-naturalis-a-traditional-chinese-medicine-formula-on-the-main-cyp450-activities-in-rats-using-a-cocktail-method
#4
Huan-Hua Xu, Fei-Ran Hao, Mei-Xi Wang, Si-Jia Ren, Ming Li, Hong-Ling Tan, Yu-Guang Wang, Xiang-Lin Tang, Cheng-Rong Xiao, Qian-De Liang, Yue Gao, Zeng-Chun Ma
The purpose of this work was to study the influences of Realgar-Indigo naturalis (RIF) and its principal element realgar on 4 main cytochrome P450 enzymes activities in rats. A simple and efficient cocktail method was developed to detect the four probe drugs simultaneously. In this study, Wistar rats were administered intragastric RIF and realgar for 14 days; mixed probe drugs were injected into rats by caudal vein. Through analyzing the pharmacokinetic parameter of mixed probe drugs in rats, we can calculate the CYPs activities...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28420163/beneficial-effects-of-melatonin-on-the-in-vitro-maturation-of-sheep-oocytes-and-its-relation-to-melatonin-receptors
#5
Xiuzhi Tian, Feng Wang, Lu Zhang, Changjiu He, Pengyun Ji, Jing Wang, Zhenzhen Zhang, Dongying Lv, Wusiman Abulizi, Xuguang Wang, Zhengxing Lian, Guoshi Liu
(1) Background: The binding sites of melatonin, as a multifunctional molecule, have been identified in human, porcine, and bovine samples. However, the binding sites and mechanisms of melatonin have not been reported in sheep; (2) Methods: Cumulus-oocyte complexes (COCs) were cultured in TCM-199 supplemented with melatonin at concentrations of 0, 10(-3), 10(-5), 10(-7), 10(-9), and 10(-11) M. Melatonin receptors (MT1 and MT2) were evaluated via immunofluorescence and Western blot. The effects of melatonin on cumulus cell expansion, nuclear maturation, embryo development, and related gene (GDF9, DNMT1, PTX3, HAS2, and EGFR) expression were investigated...
April 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28417089/demographic-and-medication-characteristics-of-traditional-chinese-medicine-users-among-colorectal-cancer-survivors-a-nationwide-database-study-in-taiwan
#6
Chien-Tung Wu, Yueh-Ting Tsai, Jung-Nien Lai
Chinese herbal product (CHP) is the major type of traditional Chinese medicine (TCM) and widely used to relief the symptom of colorectal cancer. The aim of the study was to analyze the utilization of CHP for treating patients with colorectal cancer in Taiwan. The usage of CHP, frequency of services, and prescription pattern for colorectal cancer were analyzed from a randomly sampled cohort of 1 million beneficiaries from the National Health Insurance Research Database. The odds ratios for utilization of CHP were estimated with logistic regression model...
April 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28415616/z-ligustilide-restores-tamoxifen-sensitivity-of-era-negative-breast-cancer-cells-by-reversing-mta1-ifi16-hdacs-complex-mediated-epigenetic-repression-of-era
#7
Hui Ma, Li Li, Guojun Dou, Chengqiang Wang, Juan Li, Hui He, Mingxia Wu, Hongyi Qi
Emerging evidence indicates epigenetic modification represses estrogen receptor α (ERα) and contributes to the resistance to tamoxifen in aggressive ERα-negative (ERα-) breast cancer. Z-ligustilide is a major compound in Radix Angelica sinensis, an herb from traditional Chinese medicine (TCM) most frequently prescribed for breast cancer. However, the role of Z-ligustilide in ERα- breast cancer and epigenetic modification remains largely unknown. Herein we showed, for the first time, that Z-ligustilide restored the growth inhibition of tamoxifen on ERα- breast cancer cells...
March 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28413958/anti-fatigue-effects-of-active-ingredients-from-traditional-chinese-medicine-a-review
#8
Si-Si Zhou, Jian-Guo Jiang
Fatigue, a phenomenon which is believed to be caused by body exercise, can lead to the failure of predetermined exercise intensity maintenance and sport ability declination. The usage of traditional Chinese medicine (TCM) in the treatment of fatigue has long been practiced in clinical and showed significant effects. This article covers related literatures in recent years and sorts the effective ingredients from TCM for treating fatigue into a few categories including alkaloids, saponins, polysaccharides, polyphenols, polypeptide, terpene, proteins and other active ingredients...
April 14, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28412685/tcm-comprehensive-nursing-intervention-to-pathological-jaundice-on-neonate
#9
Jie Li, Weihua Chen, Guihua Xu
Pathological Jaundice on neonate differs from that of physiologic jaundice. They perform differently on clinical cases, which is an effective way to distinguish them. There are many causes for pathological jaundice, common ones include hemolytic jaundice, infectious jaundice, obstructive jaundice, breast-feeding jaundice, etc. Clinically proven that pathological jaundices has significant differences in symptoms. This brings problems to its treatment and nursing. In recent years, TCM comprehensive nursing shows great results in treating process...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28412682/application-frequency-and-therapeutic-effect-of-astragalus-in-treating-ischemic-cerebrovascular-disease
#10
Yajie Dong, Kaifeng Lu, Weijuan Gao
In recent years, Traditional Chinese Medicine (TCM) therapy has achieved substantial progress and development, playing an important role in clinical practice. In this paper, to explore the therapeutic effect of Astragalus in treating ischemic cerebrovascular disease, 2687 patients with ischemic cerebrovascular disease who had been treated with Astragalus therapy from Jan 2014-Oct 2015 were selected as the research objects. Through retrospective analysis of their medical records, we analyzed the application frequency of Astragalus using quantitative method of information, and conducted specific analysis on the therapeutic effect of Astragalus after fully surveyed patients' physical conditions after treatment...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28412678/clinical-study-of-lung-supplementing-and-stasis-dissolving-decoction-bufei-huayu-tang-combined-with-gefitnib-for-treatment-of-advanced-non-small-cell-lung-cancer
#11
Feng Yuan, Chen Si-Ning, Zhou Ji-Hong, Jiang Ying, Zhou Ying, Xie You-Ke, Li Jian-Zhe
To investigate the clinical efficacy and drug safety of Lung-Supplementing and Stasis-Dissolving Decoction (Bufei Huayu Tang) combined with gefitnib for treatment of advanced non-small cell lung cancer (NSCLC). Then, 80 patients with advanced NSCLC hospitalized in Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine were included, and were double-blindly randomized into 4 groups: control group (gefitinib alone 250mg, once daily), low-dose group (100mL/day), middle-dose group (150mL/day) and high-dose group (200mL/day) treated with different doses of Bufei Huayu Tang besides gefitinib...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28412226/expression-profiling-based-clustering-of-healthy-subjects-recapitulates-classifications-defined-by-clinical-observation-in-chinese-medicine
#12
Ruoxi Yu, Dan Liu, Yin Yang, Yuanyuan Han, Lingru Li, Luyu Zheng, Ji Wang, Yan Zhang, Yingshuai Li, Qian-Fei Wang, Qi Wang
Differences between healthy subjects and associated disease risks are of substantial interest in clinical medicine. Based on clinical presentations, Traditional Chinese Medicine (TCM) classifies healthy people into nine constitutions: Balanced, Qi, Yang or Yin deficiency, Phlegm-dampness, Damp-heat, Blood stasis, Qi stagnation, and Inherited special constitutions. In particular, Yang and Yin deficiency constitutions exhibit cold and heat aversion, respectively. However, the intrinsic molecular characteristics of unbalanced phenotypes remain unclear...
January 17, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28410453/effects-of-acupuncture-on-gait-of-patients-with-multiple-sclerosis
#13
Maria Begoña Criado, Maria João Santos, Jorge Machado, Arminda Manuela Gonçalves, Henry Johannes Greten
Multiple sclerosis is considered a complex and heterogeneous disease. Approximately 85% of patients with multiple sclerosis indicate impaired gait as one of the major limitations in their daily life. Acupuncture studies found a reduction of spasticity and improvement of fatigue and imbalance in patients with multiple sclerosis, but there is a lack of studies regarding gait. We designed a study of acupuncture treatment, according to the Heidelberg model of Traditional Chinese Medicine (TCM), to investigate if acupuncture can be a useful therapeutic strategy in patients with gait impairment in multiple sclerosis of relapsing-remitting type...
April 14, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28405790/csh-guidelines-for-the-diagnosis-and-treatment-of-drug-induced-liver-injury
#14
EDITORIAL
Yue-Cheng Yu, Yi-Min Mao, Cheng-Wei Chen, Jin-Jun Chen, Jun Chen, Wen-Ming Cong, Yang Ding, Zhong-Ping Duan, Qing-Chun Fu, Xiao-Yan Guo, Peng Hu, Xi-Qi Hu, Ji-Dong Jia, Rong-Tao Lai, Dong-Liang Li, Ying-Xia Liu, Lun-Gen Lu, Shi-Wu Ma, Xiong Ma, Yue-Min Nan, Hong Ren, Tao Shen, Hao Wang, Ji-Yao Wang, Tai-Ling Wang, Xiao-Jin Wang, Lai Wei, Qing Xie, Wen Xie, Chang-Qing Yang, Dong-Liang Yang, Yan-Yan Yu, Min-de Zeng, Li Zhang, Xin-Yan Zhao, Hui Zhuang
Drug-induced liver injury (DILI) is an important clinical problem, which has received more attention in recent decades. It can be induced by small chemical molecules, biological agents, traditional Chinese medicines (TCM), natural medicines (NM), health products (HP), and dietary supplements (DS). Idiosyncratic DILI is far more common than intrinsic DILI clinically and can be classified into hepatocellular injury, cholestatic injury, hepatocellular-cholestatic mixed injury, and vascular injury based on the types of injured target cells...
April 12, 2017: Hepatology International
https://www.readbyqxmd.com/read/28404902/mechanism-of-modulation-through-pi3k-akt-pathway-about-nepeta-cataria-l-s-extract-in-non-small-cell-lung-cancer
#15
Jiaxin Fan, Yongrui Bao, Xiansheng Meng, Shuai Wang, Tianjiao Li, Xin Chang, Guanlin Yang, Tao Bo
Non-small cell lung cancer (NSCLC) is regarded as one of the major intractable diseases, which was cured mainly by chemotherapeutics in the clinical treatment at present. But it is still a vital mission for the current medical and researchers that hunting a natural medicine which have little side effects and high-efficiency against the NSCLC on account of the shortcomings on current drugs. Nepeta cataria L. plays an important role in anti-cancer treatment according to the reports which was recorded in the Chinese Pharmacopoeia of version 2015 and belongs to one of the Traditional Chinese medicine (TCM)...
February 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28400847/gengnianchun-a-traditional-chinese-medicine-enhances-oxidative-stress-resistance-and-lifespan-in-caenorhabditis-elegans-by-modulating-daf-16-foxo
#16
Fanhui Meng, Jun Li, Wenjun Wang, Yan Fu
Objective. Gengnianchun (GNC), a traditional Chinese medicine (TCM), is primarily used to improve declining functions related to aging. In this study, we investigated its prolongevity and stress resistance properties and explored the associated regulatory mechanism using a Caenorhabditis elegans model. Methods. Wild-type C. elegans N2 was used for lifespan analysis and oxidative stress resistance assays. Transgenic animals were used to investigate pathways associated with antioxidative stress activity. The effects of GNC on levels of reactive oxygen species (ROS) and expression of specific genes were examined...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28399500/on-line-monitoring-of-extraction-process-of-flos-lonicerae-japonicae-using-near-infrared-spectroscopy-combined-with-synergy-interval-pls-and-genetic-algorithm
#17
Yue Yang, Lei Wang, Yongjiang Wu, Xuesong Liu, Yuan Bi, Wei Xiao, Yong Chen
There is a growing need for the effective on-line process monitoring during the manufacture of traditional Chinese medicine to ensure quality consistency. In this study, the potential of near infrared (NIR) spectroscopy technique to monitor the extraction process of Flos Lonicerae Japonicae was investigated. A new algorithm of synergy interval PLS with genetic algorithm (Si-GA-PLS) was proposed for modeling. Four different PLS models, namely Full-PLS, Si-PLS, GA-PLS, and Si-GA-PLS, were established, and their performances in predicting two quality parameters (viz...
April 6, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28399164/sequential-monitoring-of-lymphocyte-subsets-and-of-t-and-b-cell-neogenesis-indexes-to-identify-time-varying-immunologic-profiles-in-relation-to-graft-versus-host-disease-and-relapse-after-allogeneic-stem-cell-transplantation
#18
Cristina Skert, Simone Perucca, Marco Chiarini, Viviana Giustini, Alessandra Sottini, Claudia Ghidini, Stefano Martellos, Federica Cattina, Benedetta Rambaldi, Valeria Cancelli, Michele Malagola, Alessandro Turra, Nicola Polverelli, Simona Bernardi, Luisa Imberti, Domenico Russo
T and B lymphocyte subsets have been not univocally associated to Graft-versus-host disease (GVHD) and relapse of hematological malignancies after stem cell transplantation (SCT). Their sequential assessment together with B and T cell neogenesis indexes has been not thoroughly analysed in relation to these changing and interrelated immunologic/clinic events yet. Lymphocyte subsets in peripheral blood (PB) and B and T cell neogenesis indexes were analysed together at different time points in a prospective study of 50 patients...
2017: PloS One
https://www.readbyqxmd.com/read/28397057/clinical-application-analysis-of-andrographolide-total-ester-sulfonate-injection-a-traditional-chinese-medicine-licensed-in-china
#19
Ying Zhao, Pu Huang, Zhe Chen, Si-Wei Zheng, Jin-Yang Yu, Chen Shi
Andrographolide total ester sulfonate (ATES) injection is one of the products of traditional Chinese medicine (TCM) currently used against viral infection in China. ATES injection was approved for manufacturing and marketing in January 2002. It is indicated for acute respiratory infections, tonsillitis, chronic obstructive pulmonary disease, influenza, foot and mouth disease, bronchiolitis, herpangina, mumps, infectious mononucleosis and psychosis. However, its usage also carries risk. We investigated the use of ATES at the Wuhan Union Hospital from January 2014 to December 2014 and evaluated its real-world clinical application using the hospital centralized monitoring method...
April 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28396565/a-clinical-and-mechanistic-study-of-topical-borneol-induced-analgesia
#20
Shu Wang, Dan Zhang, Jinsheng Hu, Qi Jia, Wei Xu, Deyuan Su, Hualing Song, Zhichun Xu, Jianmin Cui, Ming Zhou, Jian Yang, Jianru Xiao
Bingpian is a time-honored herb in traditional Chinese medicine (TCM). It is an almost pure chemical with a chemical composition of (+)-borneol and has been historically used as a topical analgesic for millennia. However, the clinical efficacy of topical borneol lacks stringent evidence-based clinical studies and verifiable scientific mechanism. We examined the analgesic efficacy of topical borneol in a randomized, double-blind, placebo-controlled clinical study involving 122 patients with postoperative pain...
April 10, 2017: EMBO Molecular Medicine
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