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https://www.readbyqxmd.com/read/28894725/safety-of-checkpoint-inhibitors-for-cancer-treatment-strategies-for-patient-monitoring-and-management-of-immune-mediated-adverse-events
#1
REVIEW
Marianne Davies, Emily A Duffield
Immune checkpoint inhibitors (ICPIs), in the form of monoclonal antibodies against CTLA-4, PD-1, and PD-L1, have dramatically changed the treatment approach in several advanced cancers. Due to their mechanism of action, these novel agents are associated with a unique spectrum of immune-mediated adverse events (imAEs), with a safety profile that indicates they are better tolerated than traditional chemotherapeutic agents. This article aims to provide education on the current knowledge about imAEs associated with ICPI treatment, including strategies and tools for the prompt identification, evaluation, and optimal management of these events...
2017: ImmunoTargets and Therapy
https://www.readbyqxmd.com/read/28892432/patient-clinician-communication-american-society-of-clinical-oncology-consensus-guideline
#2
Timothy Gilligan, Nessa Coyle, Richard M Frankel, Donna L Berry, Kari Bohlke, Ronald M Epstein, Esme Finlay, Vicki A Jackson, Christopher S Lathan, Charles L Loprinzi, Lynne H Nguyen, Carole Seigel, Walter F Baile
Purpose To provide guidance to oncology clinicians on how to use effective communication to optimize the patient-clinician relationship, patient and clinician well-being, and family well-being. Methods ASCO convened a multidisciplinary panel of medical oncology, psychiatry, nursing, hospice and palliative medicine, communication skills, health disparities, and advocacy experts to produce recommendations. Guideline development involved a systematic review of the literature and a formal consensus process. The systematic review focused on guidelines, systematic reviews and meta-analyses, and randomized controlled trials published from 2006 through October 1, 2016...
September 11, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28892208/perspectives-of-oncology-nurses-and-oncologists-regarding-barriers-to-working-with-patients-from-a-minority-background-systemic-issues-and-working-with-interpreters
#3
K J Watts, B Meiser, E Zilliacus, R Kaur, M Taouk, A Girgis, P Butow, D W Kissane, S Hale, A Perry, S K Aranda, D Goldstein
This study aimed to ascertain the systemic barriers encountered by oncology health professionals (HPs) working with patients from ethnic minorities to guide the development of a communication skills training programme. Twelve medical and five radiation oncologists and 21 oncology nurses were invited to participate in this qualitative study. Participants were interviewed individually or in a focus group about their experiences working with people from minority backgrounds. All interviews were transcribed verbatim and analysed thematically...
September 11, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28888499/the-efficacy-of-art-therapy-in-pediatric-oncology-patients-an-integrative-literature-review
#4
REVIEW
Bree A Aguilar
PROBLEM: Children undergoing cancer treatment experience detrimental adverse side effects that may be addressed with complementary and alternative medicine (CAM) such as art therapy. The purpose of this research was to examine the effects of art therapy in pediatric patients living with cancer. ELIGIBILITY CRITERIA: An integrative literature review was conducted using the CINAHL, OVID Medline, and PsycINFO databases. Studies were included if they were a primary source utilizing an art therapy intervention in children with cancer age birth to 18years old, was published between the year 2000 and 2016, and written in the English language...
September 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28880984/association-of-a-perioperative-education-program-with-unplanned-readmission-following-total-laryngectomy
#5
Evan M Graboyes, Dorina Kallogjeri, Jan Zerega, Sara Kukuljan, Linda Neal, Kelsey M Rosenquist, Brian Nussenbaum
Importance: Patients undergoing total laryngectomy (TL) are at high risk for 30-day hospital readmission. Strategies to decrease the readmission rate remain unknown. Objectives: To assess the association of a comprehensive perioperative TL education program with unplanned readmissions; to determine the program's association with the rate of readmissions for stomal or tracheoesophageal puncture (TEP) complications and patient and caregiver knowledge of and preparedness for TL...
September 7, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28880619/reflective-practice-applied-in-a-clinical-oncology-research-setting
#6
Laura Caley, Victoria Pittordou, Carolyn Adams, Caroline Gee, Ville Pitkahoo, Jennifer Matthews, Sarah Cruse, Ann Muls
Regular reflective practice group sessions, focusing on enhancing mindfulness, were piloted as part of a support programme for researchers in a clinical oncology setting. METHODS: As a previous systematic review highlighted a wide variety of approaches and a lack of published evidence on the use of specific models for reflective practice in health care, a scoping review of existing literature describing reflective practice models preceded piloting the programme with the research team...
September 7, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28877109/the-efficacy-of-a-viscoelastic-foam-overlay-on-prevention-of-pressure-injury-in-acutely-ill-patients-a-prospective-randomized-controlled-trial
#7
Kyung Hee Park, Joohee Park
PURPOSE: The purpose of this study was to compare a viscoelastic foam overlay (VEFO) to a standard hospital mattress for pressure injury (PI) prevention. We also compared interface pressures (IPs) of the VEFO to our facility's standard hospital mattress. DESIGN: Prospective, randomized controlled trial. SUBJECTS AND SETTING: Data analysis was based on 110 participants (55 in each group) who were 19 years or older, had a Braden Scale for Pressure Sore Risk score of 16 or less, and were cared for on a neurology, oncology, or pulmonology inpatient care unit...
September 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28876649/an-evaluation-of-epidemiological-differences-in-colorectal-cancer-patients-over-and-under-the-age-of-50-presenting-to-academic-centers-in-johannesburg
#8
B D Bebington
BACKGROUND: As in other developing countries, the nations of Sub-Saharan Africa have seen an increase in the incidence of colorectal cancer. Repeatedly, the indigenous populations have shown a skewing of incidence in favour of patients below the age of 50. As part of a larger study, and through funding from the Medical research Council of South Africa, the Wits MRC Oncology group has set out to identify the epidemiological characteristics and disease progression of patients under the age of 50 presenting with colorectal cancer...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876159/implementing-a-multidisciplinary-approach-to-enhance-compliance-with-guideline-recommended-prechemotherapy-pneumococcal-vaccination-in-a-military-based-medical-oncology-practice
#9
Wilfred Delacruz, Sandra Terrazzino, Michael Osswald, Casey Payne, Brian Haney
PURPOSE: Patients with cancer are at increased risk for invasive pneumococcal disease, including community-acquired pneumonia. Current Advisory Committee on Immunization Practices and National Cancer Comprehensive Network guidelines recommend pneumococcal vaccination for immunocompromised patients, including patients with cancer. METHODS: We conducted a quality improvement (QI) project to enhance compliance with pneumococcal vaccination in patients before their chemotherapy...
September 6, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28871358/chemotherapy-induced-nausea-and-vomiting-cinv-and-adherence-to-antiemetic-guidelines-results-of-a-survey-of-oncology-nurses
#10
Rebecca Clark-Snow, Mary Lou Affronti, Cynthia N Rittenberg
PURPOSE: Chemotherapy-induced nausea and vomiting (CINV) can be prevented in most patients with use of guideline-recommended antiemetic regimens. However, studies have suggested that adherence to antiemetic guidelines is suboptimal. Oncology nurses, as part of a multidisciplinary team, can help promote appropriate antiemetic prophylaxis. Therefore, nurses were surveyed to assess antiemetic guideline awareness and practice patterns of antiemetic use, determine adherence to guideline recommendations, and query barriers to adherence...
September 4, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28863725/clinical-practice-recommendations-based-on-an-updated-review-of-breast-cancer-risk-among-women-treated-for-childhood-cancer
#11
Yael E Derman
Breast cancer is the most common secondary malignancy among women treated for childhood cancer. This review highlights interacting etiologies contributing to development of secondary breast cancer to complement guidelines for surveillance and survivorship care and make recommendations for clinical practice. Treatment exposures determine Children's Oncology Group breast cancer surveillance guidelines; those treated with cumulative doses ≥20 Gy chest irradiation should undergo annual magnetic resonance imaging and mammography after age 25 years or 8 years after exposure, whichever comes last...
September 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28845730/organizational-and-managerial-resources-and-quality-of-care-in-french-pediatric-oncology-nursing
#12
Séverine Chevalier, Julien Lejeune, Evelyne Fouquereau, Hélène Coillot, Nicolas Gillet, Virginie Gandemer, Jean Michon, Philippe Colombat
The purpose of this study was to examine the relationships between nurses' organizational and managerial resources (ie, perceived organizational support and transformational leadership) and their quality of patient care, and second, the mediating role of job satisfaction in these relationships. Participants were 510 nurses from 25 out of 29 French pediatric oncology units. Structural equation modeling results revealed that perceived organizational support and transformational leadership were related to nurses' perceived quality of care and that job satisfaction acted as a mediator between these 2 antecedents (ie, organizational and managerial determinants) and this outcome (ie, quality of care)...
August 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28841101/implementation-and-evaluation-of-medicine-and-therapeutic-information-service-by-clinical-pharmacists-in-oncology-care-setting
#13
Himanshu Patel, Parthasarathi Gurumurthy
Background This study was conducted to explore the role of clinical pharmacists in providing medicine and therapeutic information service in oncology care setting. Methods It was a prospective study conducted for a period of three years after implementation of medicine and therapeutic information service as an integral part of oncology pharmacy services. The medicine and therapeutic information queries were received during ward rounds, at ambulatory care and via telephone by clinical pharmacists. All the medicine and therapeutic information requests were reviewed and answered to the concerned requester(s)...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28838897/rethinking-exercise-identity-a-qualitative-study-of-physically-inactive-cancer-patients-transforming-process-while-undergoing-chemotherapy
#14
Lis Adamsen, Christina Andersen, Christian Lillelund, Kira Bloomquist, Tom Møller
OBJECTIVE: To explore physically inactive breast and colon cancer patients' prediagnosis exercise history and attitudes to physical activity (PA) and experiences in initiating PA while undergoing adjuvant chemotherapy. DESIGN: An explorative qualitative study guided the interpretive analysis of semistructured, open-ended interviews conducted at initiation of chemotherapy and after 12 weeks. The study was embedded in a pilot randomised controlled trial. SETTING: Participants were recruited from the Oncological Department at a hospital in Copenhagen, Denmark...
August 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28835267/workplace-violence-in-a-tertiary-care-israeli-hospital-a-systematic-analysis-of-the-types-of-violence-the-perpetrators-and-hospital-departments
#15
Sigal Shafran-Tikva, Revital Zelker, Zvi Stern, David Chinitz
BACKGROUND: Worldwide, there is a widespread and disturbing pattern of violence towards healthcare workers. However, violent occurrences in Israeli hospitals have often been unrecognized and underreported. Moreover, most studies have not sufficiently differentiated among the different types of violence. To examine the different types of violence experienced by nurses and physicians, the types of perpetrators and the specialty fields involved. METHODS: A quantitative questionnaire was used to assess the incidence of a "basket" of violent behaviors, divided into eight types of violent manifestations...
August 23, 2017: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/28831441/pain-management-and-use-of-opioids-in-pediatric-oncology-in-india-a-qualitative-approach
#16
Paola Angelini, Katherine M Boydell, Vicky Breakey, Purna A Kurkure, Marian A Muckaden, Eric Bouffet, Brijesh Arora
PURPOSE: Consumption of medical opium for pain relief in India is low, despite the country being one of the main world producers of the substance. We investigated obstacles to opioid use and physician perceptions about optimal pain management in pediatric oncology patients in India. METHODS: Semistructured interviews were conducted with oncologists who work in pediatric oncology settings. A mixed sampling strategy was used, including maximum variation and confirmation and disconfirmation of cases, as well as snowball sampling...
August 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28820522/results-of-an-oncology-clinical-trial-nurse-role-delineation-study
#17
Michelle A Purdom, Sandra Petersen, Barbara K Haas
PURPOSE/OBJECTIVES: To evaluate the relevance of a five-dimensional model of clinical trial nursing practice in an oncology clinical trial nurse population. 
. DESIGN: Web-based cross-sectional survey.
. SETTING: Online via Qualtrics.
. SAMPLE: 167 oncology nurses throughout the United States, including 41 study coordinators, 35 direct care providers, and 91 dual-role nurses who provide direct patient care and trial coordination...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28820520/response-to-assessing-the-impact-of-acupuncture-on-pain-nausea-anxiety-and-coping-in-women-undergoing-a-mastectomy
#18
Jose M Moran, Antonio S Fernández, Juan D Pedrera-Zamorano
We read with interest the pilot randomized, controlled trial by Quinlan-Woodward et al. (2016) published in Oncology Nursing Forum about the impact of acupuncture on pain, nausea, anxiety, and coping in women undergoing a mastectomy. We think that there are both theoretical and methodologic issues that do not allow the authors to conclude that their study demonstrated that acupuncture delivered postoperatively in the hospital after mastectomy can reduce the severity of symptoms experienced and increase the patient's ability to cope with her symptoms...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28820519/how-the-consolidated-framework-for-implementation-research-can-strengthen-findings-and-improve-translation-of-research-into-practice-a-case-study
#19
Nadja Klafke, Cornelia Mahler, Cornelia von Hagens, Michel Wensing, Andreas Schneeweiss, Andreas Müller, Joachim Szecsenyi, Stefanie Joos
PURPOSE/OBJECTIVES: To answer how the planned intervention was performed in routine care, which factors supported or distracted from its implementation, and how key organizational structures have been built and sustained.
. RESEARCH APPROACH: Mixed-methods process evaluation.
. SETTING: Two German outpatient cancer clinics.
. PARTICIPANTS: Purposive sampling of 297 recruited patients with gynecologic cancer, their treating oncology nurses, and their interprofessional healthcare team, and the clinical stakeholders of two different outpatient cancer clinics...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28820515/the-role-of-oncology-nurses-in-discussing-clinical-trials
#20
Susan A Flocke, Elizabeth Antognoli, Barbara J Daly, Brigid Jackson, Sarah E Fulton, Tasnuva M Liu, Jessica Surdam, Sharon Manne, Neal J Meropol
PURPOSE/OBJECTIVES: To describe oncology nurses' experiences discussing clinical trials with their patients, and to assess barriers to these discussions.
. RESEARCH APPROACH: A qualitative study designed to elicit narratives from oncology nurses. 
. SETTING: Community- and academic-based oncology clinics throughout the United States.
. PARTICIPANTS: 33 oncology nurses involved in direct patient care in community-based and large hospital-based settings...
September 1, 2017: Oncology Nursing Forum
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