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https://www.readbyqxmd.com/read/28944679/risk-and-protective-factors-for-health-related-quality-of-life-among-persons-aging-with-hiv
#1
Annie L Nguyen, Candice J McNeil, S Duke Han, Scott D Rhodes
For persons living with HIV, health-related quality of life (HRQOL) may be threatened by physical and mental conditions but may be protected by positive psychological traits. We performed an exploratory look at the risk and protective factors for HRQOL in older adults living with HIV. Cross-sectional analyses of baseline data from the Rush Center of Excellence on Disparities in HIV and Aging (CEDHA), a community-based cohort of persons ages ≥50 living with HIV (n = 176) were performed. Analyses examined the relationship between risk/protective factors and two outcomes (i...
September 25, 2017: AIDS Care
https://www.readbyqxmd.com/read/28944609/hypertension-management-research-priorities-from-patients-caregivers-and-healthcare-providers-a-report-from-the-hypertension-canada-priority-setting-partnership-group
#2
Nadia Khan, Simon L Bacon, Samia Khan, Sara Perlmutter, Carline Gerlinsky, Mark Dermer, Lonni Johnson, Finderson Alves, Donna McLean, Andreas Laupacis, Mandy Pui, Angelique Berg, Felicia Flowitt
Patient- and stakeholder-oriented research is vital to improving the relevance of research. The authors aimed to identify the 10 most important research priorities of patients, caregivers, and healthcare providers (family physicians, nurses, nurse practitioners, pharmacists, and dietitians) for hypertension management. Using the James Lind Alliance approach, a national web-based survey asked patients, caregivers, and care providers to submit their unanswered questions on hypertension management. Questions already answered from randomized controlled trial evidence were removed...
September 25, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28944591/the-impact-of-muc5b-gene-on-dental-caries
#3
Tayla Cavallari, Heloísa Salomão, Simone Tetu Moysés, Samuel Jorge Moysés, Renata Iani Werneck
OBJECTIVE: To identify the impact of MUC5B polymorphisms on dental caries. METHODS: A case-control study was performed with patients recruited at Pontifícia Universidade Católica do Paraná. This individuals were aged 12 years old or more. Dental caries was diagnosed using the International Caries Detection and Assessment System and the effects of socioeconomic, dietary, and hygiene factors on dental caries were investigated. Furthermore, buccal cells were collected, and their DNA was extracted and amplified using PCR...
September 25, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28944526/state-medicaid-fees-and-access-to-primary-care-physicians
#4
Rajiv Sharma, Sarah Tinkler, Arnab Mitra, Sudeshna Pal, Raven Susu-Mago, Miron Stano
Medicaid and uninsured patients are disadvantaged in access to care and are disproportionately Black and Hispanic. Using a national audit of primary care physicians, we examine the relationship between state Medicaid fees for primary care services and access for Medicaid, Medicare, uninsured, and privately insured patients who differ by race/ethnicity and sex. We found that states with higher Medicaid fees had higher probabilities of appointment offers and shorter wait times for Medicaid patients, and lower probabilities of appointment offers and longer wait times for uninsured patients...
September 24, 2017: Health Economics
https://www.readbyqxmd.com/read/28944516/innovation-or-violation-leveraging-mobile-technology-to-conduct-socially-responsible-community-research
#5
Amanda L Roy
Mobile technology is increasingly being used to measure individuals' moods, thoughts, and behaviors in real time. Current examples include the use of smartphones to collect ecological momentary assessments (EMAs; assessments delivered "in the moment"); wearable technology to passively collect objective measures of participants' movement, physical activity, sleep, and physiological response; and smartphones and wearable devices with global positioning system (GPS) capabilities to collect precise information about where participants spend their time...
September 25, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28944484/the-stem-cell-club-a-model-for-unrelated-stem-cell-donor-recruitment
#6
Warren Fingrut, Simran Parmar, Ari Cuperfain, Kiran Rikhraj, Erin Charman, Emilie Ptak, Manjot Kahlon, Alice Graham, Susan Luong, Yongjun George Wang, Janice Yu, Neha Arora, Roopa Suppiah, Edward W Li, Anna Lee, Christopher Welsh, Menachem Benzaquen, Alicia Thatcher, Iman Baharmand, Aedan Ladd, Tanya Petraszko, David Allan, Hans Messner
BACKGROUND: Patients with blood, immune, or metabolic diseases may require a stem cell transplant as part of their treatment. However, 70% of patients do not have a suitable human leukocyte antigen match in their family, and need an unrelated donor. Individuals can register as potential donors at stem cell drives, where they provide consent and a tissue sample for human leukocyte antigen typing. The ideal donors are young, male, and from a diversity of ethnic backgrounds. However, in Canada, non-Caucasian males ages 17 to 35 years represent only 8...
September 24, 2017: Transfusion
https://www.readbyqxmd.com/read/28944467/olfactory-dysfunction-predicts-subsequent-dementia-in-older-u-s-adults
#7
Dara R Adams, David W Kern, Kristen E Wroblewski, Martha K McClintock, William Dale, Jayant M Pinto
OBJECTIVES: To investigate the relationship between olfactory dysfunction and subsequent diagnosis of dementia. DESIGN: Longitudinal study of a population representative of U.S. older adults. SETTING: Home interviews (National Social Life, Health, and Aging Project). PARTICIPANTS: Men and women aged 57 to 85 (N = 2,906). MEASUREMENTS: Objective odor identification ability was measured at baseline using a validated five-item test...
September 25, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28944430/polymorphism-of-matrix-metalloproteinases-genes-mmp1-mmp2-mmp3-and-mmp7-and-the-risk-of-varicose-veins-of-lower-extremities
#8
A S Shadrina, M A Smetanina, K S Sevost'yanova, A I Shevela, E I Seliverstov, E A Zakharova, E N Voronina, E A Ilyukhin, I A Zolotukhin, A I Kirienko, M L Filipenko
We studied the effects of single nucleotide polymorphisms in the promoter regions of matrix metalloproteinase genes rs1799750 (-1607dupG) MMP1, rs243865 (C-1306T) MMP2, rs3025058 (-1171dupA) MMP3, and rs11568818 (A-181G) MMP7 on the risk of varicose vein of the lower extremities in ethnical Russians, residents of the Russian Federation. We genotyped 536 patients with this pathology and 273 healthy participants without history of chronic venous disease. Association was examined using logistic regression analysis...
September 25, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28944291/acceptability-of-chairside-screening-for-racial-ethnic-minority-older-adults-a-qualitative-study
#9
A P Greenblatt, I Estrada, E W Schrimshaw, S S Metcalf, C Kunzel, M E Northridge
An aging and more racially and ethnically diverse population, coupled with changes in the health care policy environment, is demanding that the dental profession both redirect and expand its focus. Challenges include providing comprehensive care for patients with complicated medical needs while improving access to care for underserved groups. The purpose of this study is to examine the acceptability of screening for hypertension and diabetes in the dental setting for African American, Puerto Rican, and Dominican older adults who attend senior centers in northern Manhattan, New York City...
October 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28944289/video-intervention-increases-participation-of-black-breast-cancer-patients-in-therapeutic-trials
#10
Brandi N Robinson, Antoinette F Newman, Eshetu Tefera, Pia Herbolsheimer, Raquel Nunes, Christopher Gallagher, Pamela Randolph-Jackson, Adedamola Omogbehin, Asma Dilawari, Paula R Pohlmann, Mahsa Mohebtash, Young Lee, Yvonne Ottaviano, Avani Mohapatra, Filipa Lynce, Richard Brown, Mihriye Mete, Sandra M Swain
There is a striking racial and ethnic disparity in incidence and mortality of cancer yet minorities remain markedly underrepresented in clinical trials. This pilot study set out to determine the impact of a 15-min culturally tailored educational video on three outcomes relating to clinical trials: likely participation, attitudes (assessed based on six barriers), and actual enrollment. Breast cancer patients with Stage I-III, if diagnosed within previous 6 months, or metastatic disease who self-identified as black or African American were invited to participate...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28944235/assessing-risk-for-mendelian-disorders-in-a-bronx-population
#11
Guy diSibio, Kinnari Upadhyay, Philip Meyer, Carole Oddoux, Harry Ostrer
BACKGROUND: To identify variants likely responsible for Mendelian disorders among the three major ethnic groups in the Bronx that might be useful to include in genetic screening panels or whole exome sequencing filters and to estimate their likely prevalence in these populations. METHODS: Variants from a high-density oligonucleotide screen of 192 members from each of the three ethnic-national populations (African Americans, Puerto Ricans, and Dominicans) were evaluated for overlap with next generation sequencing data...
September 2017: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/28944165/sleep-trajectories-before-and-after-the-final-menstrual-period-in-the-study-of-women-s-health-across-the-nation-swan
#12
Howard M Kravitz, Imke Janssen, Joyce T Bromberger, Karen A Matthews, Martica H Hall, Kristine Ruppert, Hadine Joffe
PURPOSE OF REVIEW: Longitudinal studies show that the menopausal transition (MT) is associated with poorer self-reported sleep. Increases in sleep disturbances across and beyond the MT are strongly associated with vasomotor symptoms (VMS) but occur even without VMS. We analyzed data from baseline through 13 annual or biennial follow-up assessments from SWAN's multi-racial/ethnic cohort of midlife women, specifically focusing on patterns of sleep problems in the years preceding and following the final menstrual period (FMP)...
September 2017: Current Sleep Medicine Reports
https://www.readbyqxmd.com/read/28944157/problem-gambling-among-ethnic-minorities-results-from-an-epidemiological-study
#13
Kyle R Caler, Jose Ricardo Vargas Garcia, Lia Nower
A few studies have examined gambling behavior and problem gambling among minorities and reported higher rates of both participation and gambling problems among particular minority groups in comparison to Whites who gamble. The present study utilized a representative, epidemiological sample of adults in New Jersey to explore gambling behavior, gambling problem severity, substance use, problem behavior, and mental health issues among minorities. Univariate analyses were conducted, comparing Whites (n = 1341) to respondents who identified as Hispanic (n = 394), Black (n = 261), or Asian/other (n = 177)...
2017: Asian journal of gambling issues and public health
https://www.readbyqxmd.com/read/28944108/the-association-of-posttraumatic-stress-disorder-and-chronic-medical-conditions-by-ethnicity
#14
Sarah E Valentine, Carrie J Nobles, Monica W Gerber, Adin Vaewsorn, Derri L Shtasel, Luana Marques
Our study extends the literature on associations between posttraumatic stress disorder (PTSD) and chronic medical conditions by assessing differences in the magnitude of these relations by ethnicity. We examined group differences in the magnitude of the relation between PTSD and chronic medical conditions (cardiovascular disease [CVD], hypertension, obesity, diabetes). We obtained data from Latino (n = 3,224) and non-Latino white (n = 4,180) respondents from the Collaborative Psychiatric Epidemiology Surveys...
August 2017: Journal of Latina/o Psychology
https://www.readbyqxmd.com/read/28943819/evaluation-of-safety-in-exceeding-maximum-adult-doses-of-commonly-used-second-generation-antiepileptic-drugs-in-pediatric-patients
#15
Mindl M Messinger, Sunita N Misra, Gary D Clark, Shannon M DiCarlo
OBJECTIVE: Pediatric patients often require larger doses of antiepileptic drug (AED) than adults in order to attain therapeutic serum concentrations and/or achieve seizure control. Safety and efficacy data are often extrapolated from adult literature; hence, optimal dosage may only be determined anecdotally or based on expert opinion. With limited pediatric dosing guidelines, milligrams per day that are based on weight may exceed the maximum adult dose. The primary objective of this study is to evaluate the safety of exceeding maximum doses as specified by the US Food and Drug Administration or manufacturers of commonly used AEDs in pediatric patients...
July 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28943747/african-american-and-black-caribbean-feelings-of-closeness-to-africans
#16
Michael C Thornton, Robert Joseph Taylor, Linda M Chatters, Ivy Forsythe-Brown
African American and Black Caribbean relations dominate research on interactions across black ethnic divides. Using National Survey of American Life data, we explore a different aspect of black interethnic attitudes: how close these groups feel toward Africans. African Americans and Black Caribbeans were largely similar in their feelings of closeness to Africans. For Black Caribbeans, younger and male respondents, those reporting higher levels of financial strain, living in the northeast and persons who immigrated to the United States at least 11 years ago, report feeling especially close to Africans...
2017: Identities (Yverdon)
https://www.readbyqxmd.com/read/28943685/disciplinary-practices-metaparenting-and-the-quality-of-parent-child-relationships-in-african-american-mexican-american-and-european-american-mothers
#17
George W Holden, Carol Kozak Hawk, Margaret M Smith, Jimmy Singh, Rose Ashraf
Coercive responses to children's behavior are well recognized to be problematic for children's adjustment. Less well understood is how parental social cognition is linked to discipline. In this study we sought to link metaparenting - parents' thoughts about their parenting - to the use of coercive discipline. We predicted that mothers who engaged in more metaparenting, thus reflecting more deliberate parenting, would use corporal punishment less frequently and instead engage in non-coercive discipline. We also expected that mothers who engaged in more metaparenting would report closer relationships with their children...
2017: International Journal of Behavioral Development
https://www.readbyqxmd.com/read/28943464/the-spectrum-of-familial-mediterranean-fever-gene-mefv-mutations-and-genotypes-in-iran-and-report-of-a-novel-missense-variant-r204h
#18
Nader Ebadi, Abbas Shakoori, Masoumeh Razipour, Arash Salmaninejad, Razieh Zarifian Yeganeh, Saman Mehrabi, Seyed RezaRaees Karami, Malihea Khaleghian, Hamidreza Azhideh
BACKGROUND: Familial Mediterranean Fever (FMF) is an autosomal recessive disorder, characterized by recurrent and self-limited episodes of fever, abdominal pain, synovitis and pleuritis. FMF as the most common inherited monogenic autoinflammatory disease mainly affects ethnic groups of the Mediterranean basin, Arab, Jewish, Turkish, Armenian North Africans and Arabic descent. MATERIALS AND METHODS: In the present study, we selected 390 unrelated FMF patients according to the Tel-Hashomer criteria, and analyzed all patients for 12 most common mutations of MEFV gene by reverse hybridization assay (FMF strip assay)...
September 21, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28943344/polymorphisms-of-the-folate-metabolizing-enzymes-association-with-sle-susceptibility-and-in-silico-analysis
#19
Saeedeh Salimi, Farshid Keshavarzi, Abbas Mohammadpour-Gharehbagh, Mahdieh Moodi, Mahdieh Mousavi, Mohammad Karimian, Mahnaz Sandoughi
Systemic lupus erythematosus (SLE) is a typical autoimmune disorder with multiple organ involvement and unknown etiology. It has been shown that polymorphic variants of the genes encoding key enzymes of folate and methionine metabolism may influence DNA methylation. Genomic DNA was extracted from blood samples of 150 SLE patients and 160 controls, matching age, sex, and ethnicity. MTHFR rs1801133C>T and MTR rs1805087A>G polymorphisms were genotyped by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method...
September 21, 2017: Gene
https://www.readbyqxmd.com/read/28943266/ethnic-cleansing-in-myanmar-the-rohingya-crisis-and-human-rights
#20
Chris Beyrer, Adeeba Kamarulzaman
No abstract text is available yet for this article.
September 21, 2017: Lancet
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