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https://www.readbyqxmd.com/read/29925111/prenatal-care-and-hypertensive-gestational-syndromes-a-systematic-review
#1
Gláucya Raquel Souza da Fonsêca Dutra, Laio da Costa Dutra, Gabriela Karine Souza da Fonsêca, Mauro Bezerra do Nascimento Júnior, Eudes Euler de Souza Lucena
OBJECTIVE:  Evaluate the influence of prenatal care on the occurrence of gestational hypertension. METHODS:  The Web of Science, Scopus, Pubmed, Cochrane and ClinicalTrials electronic databases were searched for articles published between January 1st , 2012 and December 31st , 2016. No language restrictions were imposed. The following keywords were used: prenatal care, medical assistance, prenatal education, pregnancy-induced hypertension. The preferred reporting items for systematic reviews and meta-analyses (PRISMA) checklist was employed...
June 20, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29925103/medium-to-long-term-results-of-the-nexgen-legacy-posterior-stabilized-fixed-bearing-knee-replacement
#2
Oommen Mathew Arikupurathu, Linda Johnston, Alasdair MacInnes, Graeme Nicol, Manhal Nassif
The NexGen legacy posterior stabilized (LPS) prosthesis was introduced in 1997 after many design changes to its predecessor, the Insall-Burstein II prosthesis. However, there have been no reported long-term studies on the performance of this implant. Prospectively, collected data from a local database comprising primary total knee replacements (TKRs) with LPS between 1997 and 2002 was analyzed. All implants were fixed with cement. Patients were followed up at 1, 3, 5, 7, and 10 years, with patient satisfaction, range of movement, and Knee Society score (KSS) assessed...
June 20, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29925095/coronary-artery-bypass-grafting-in-diabetic-patients-complete-arterial-versus-internal-thoracic-artery-and-sequential-vein-grafts-a-propensity-score-matched-analysis
#3
Takashi Kunihara, Olaf Wendler, Kerstin Heinrich, Ryota Nomura, Hans-Joachim Schäfers
BACKGROUND:  The optimal choice of conduit and configuration for coronary artery bypass grafting (CABG) in diabetic patients remains somewhat controversial, even though arterial grafts have been proposed as superior. We attempted to clarify the role of complete arterial revascularization using the left internal thoracic artery (LITA) and the radial artery (RA) alone in "T-Graft" configuration on long-term outcome. METHODS AND RESULTS:  From 1994 to 2001, 104 diabetic patients with triple vessel disease underwent CABG using LITA/RA "T-Grafts" (Group-A)...
June 20, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29925087/is-a-yoga-based-program-with-potential-to-decrease-falls-perceived-to-be-acceptable-to-community-dwelling-people-older-than-60
#4
Anne Tiedemann, Sandra O'Rourke, Catherine Sherrington
Objectives and importance of study: Yoga improves balance and mobility, and therefore has potential as a fall prevention strategy, yet its validity for preventing falls has not been established. The Otago Exercise Programme (OEP) and tai chi are proven to prevent falls. This study aimed to evaluate the perceptions and preferences of older people towards a yoga-based program with potential to decrease falls, to compare these perceptions to the views expressed about the OEP and tai chi, and to identify participant characteristics associated with a preference for the yoga program...
June 14, 2018: Public Health Research & Practice
https://www.readbyqxmd.com/read/29925065/impact-of-laparoscopic-repair-of-large-hiatus-hernia-on-quality-of-life-observational-cohort-study
#5
Stefano Siboni, Emanuele Asti, Pamela Milito, Gianluca Bonitta, Andrea Sironi, Alberto Aiolfi, Luigi Bonavina
BACKGROUND: Laparoscopic surgery has proven safe and effective in the treatment of large hiatus hernia. Differences may exist between objectively assessed surgical outcomes, symptomatic scores, and patient-reported outcomes. METHODS: An observational, single-arm cohort study was conducted in patients undergoing primary laparoscopic repair with crura mesh augmentation and Toupet fundoplication for large (> 50% of intrathoracic stomach) type III-IV hiatus hernia...
June 20, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29925064/once-weekly-administration-of-sustained-release-growth-hormone-in-korean-prepubertal-children-with-idiopathic-short-stature-a-randomized-controlled-phase-ii-study
#6
Jin Soon Hwang, Hae Sang Lee, Kee-Hyoung Lee, Han-Wook Yoo, Dae-Yeol Lee, Byung-Kyu Suh, Cheol Woo Ko, Woo Yeong Chung, Dong-Kyu Jin, Choong Ho Shin, Heon-Seok Han, Song Han, Ho-Seong Kim
BACKGROUND/AIMS: To determine the optimal dose of LB03002, a sustained-release, once-weekly formulation of recombinant human growth hormone (rhGH), and to compare its efficacy and safety with daily rhGH in children with idiopathic short stature (ISS). METHODS: This multicenter, randomized, open-label, phase II study included GH-naïve, prepubertal children with ISS, randomized to receive daily rhGH 0.37 mg/kg/week (control, n = 16), LB03002 0.5 mg/kg/week (n = 14), or LB03002 0...
June 20, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29925048/prognostic-value-of-nerve-ultrasound-and-electrophysiological-findings-in-traumatic-sural-neuropathy
#7
A Kerasnoudis, P Ntasiou, G Barmpalios
INTRODUCTION: We report on the prognostic role of cross sectional area (CSA) enlargement and axonal damage in traumatic sural neuropathy (TSN). METHODS: Reference values were defined in 23 healthy subjects. 13patients with TSN underwent evaluation (Thessaloniki Hypesthesia Score (THS), ultrasound, electrophysiology). All patients were followed up with THS 6 months after initial evaluation. RESULTS: During initial evaluation, the 13 patients showed a mean THS of 2...
June 13, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29925044/a-systematic-review-of-patient-reported-outcomes-in-phase-ii-or-iii-clinical-trials-of-myelodysplastic-syndromes-and-acute-myeloid-leukemia
#8
REVIEW
Ashley Leak Bryant, Sarah W Drier, Sejin Lee, Antonia V Bennett
The purpose of this systematic literature review was to identify clinical trials of MDS and AML that included patient-reported outcome (PRO) instruments, and to summarize the symptom and other health related quality of life (HRQOL) concepts most frequently assessed and the PRO instruments that were used. Sixteen manuscripts describing 14 distinct trials met all criteria (i.e., phase 2 or 3 clinical trial for MDS or AML which included PRO assessment) and were published between 1996-2017. In trials evaluating anemia, PRO scores showed significant improvement in relevant domains (e...
June 7, 2018: Leukemia Research
https://www.readbyqxmd.com/read/29924893/reliability-of-heartsmap-as-a-tool-for-evaluating-psychosocial-assessment-documentation-practices-in-emergency-departments-for-pediatric-mental-health-complaints
#9
Carson Gill, Brendan Arnold, Sean Nugent, Alykhan Rajwani, Michael Xu, Tyler Black, Quynh Doan
OBJECTIVES: The goal of this study was to assess the reliability of HEARTSMAP as a standardized tool for evaluating the quality of psychosocial assessment documentation of pediatric mental health presentations to the emergency department. In addition, we report on current documentation practices. METHODS: We conducted a retrospective cross-sectional study of pediatric (up to age 17) mental health-related visits to four emergency departments between April 1, 2013 and March 31, 2014...
June 20, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29924877/anxious-gambling-anxiety-is-associated-with-higher-frontal-midline-theta-predicting-less-risky-decisions
#10
Barbara Schmidt, Hannah Kanis, Clay B Holroyd, Wolfgang H R Miltner, Johannes Hewig
In this study, we address the effect of anxiety measured with the State-Trait Anxiety Inventory (STAI) on EEG and risk decisions. We selected 20 high and 20 low anxious participants based on their STAI trait scores in the upper or lower quartile of the norm distribution and implemented a risk game developed in our laboratory. We investigate if high anxious individuals exert more cognitive control, reflected in higher frontal midline theta (FMT) power when they make a risky decision, and if they act less risky compared to low anxious individuals...
June 20, 2018: Psychophysiology
https://www.readbyqxmd.com/read/29924868/functional-levels-and-mri-patterns-of-muscle-involvement-in-upper-limbs-in-duchenne-muscular-dystrophy
#11
Claudia Brogna, Lara Cristiano, Tommaso Tartaglione, Tommaso Verdolotti, Lavinia Fanelli, Luana Ficociello, Giorgio Tasca, Roberta Battini, Giorgia Coratti, Nicola Forcina, Roberto De Santis, Giulia Norcia, Sara Carnicella, Cesare Colosimo, Pierre Carlier, Marika Pane, Eugenio Mercuri
The aim of the study was to evaluate the spectrum of upper limb functional activities and imaging finding in a cohort of patients affected by Duchenne muscular dystrophy. Thirty-one patients of age between 5 and 29 years were included in the study (17 ambulant and 14 non-ambulant). They were all assessed using the Performance of Upper Limb (PUL) test and muscle MRI of shoulder, arm and forearm in order to establish if the functional scores obtained at shoulder, mid and distal level related to specific patterns of involvement in each upper limb segment on muscle MRI...
2018: PloS One
https://www.readbyqxmd.com/read/29924864/novel-classification-for-global-gene-signature-model-for-predicting-severity-of-systemic-sclerosis
#12
Zariel I Johnson, Jacqueline D Jones, Angana Mukherjee, Dianxu Ren, Carol Feghali-Bostwick, Yvette P Conley, Cecelia C Yates
Progression of systemic scleroderma (SSc), a chronic connective tissue disease that causes a fibrotic phenotype, is highly heterogeneous amongst patients and difficult to accurately diagnose. To meet this clinical need, we developed a novel three-layer classification model, which analyses gene expression profiles from SSc skin biopsies to diagnose SSc severity. Two SSc skin biopsy microarray datasets were obtained from Gene Expression Omnibus. The skin scores obtained from the original papers were used to further categorize the data into subgroups of low (<18) and high (≥18) severity...
2018: PloS One
https://www.readbyqxmd.com/read/29924851/age-adjusted-charlson-comorbidity-index-as-a-prognostic-factor-for-radical-prostatectomy-outcomes-of-very-high-risk-prostate-cancer-patients
#13
Jae Won Park, Dong Hoon Koh, Won Sik Jang, Joo Yong Lee, Kang Su Cho, Won Sik Ham, Koon Ho Rha, Woo Hee Jung, Sung Joon Hong, Young Deuk Choi
PURPOSE: Prostate cancer (PC) is a devastating and heterogeneous condition with diverse treatment options. When selecting treatments for patients with very high-risk PC, clinicians must consider patient comorbidities. We investigated the efficacy of the age-adjusted Charlson Comorbidity Index (ACCI) as a prognostic factor for patient outcomes after radical prostatectomy (RP). MATERIALS AND METHODS: We retrospectively investigated the medical records of PC patients at our institution who underwent RP from 1992 to 2010...
2018: PloS One
https://www.readbyqxmd.com/read/29924848/upper-limb-function-in-duchenne-muscular-dystrophy-24-month-longitudinal-data
#14
Marika Pane, Giorgia Coratti, Claudia Brogna, Elena Stacy Mazzone, Anna Mayhew, Lavinia Fanelli, Sonia Messina, Adele D'Amico, Michela Catteruccia, Marianna Scutifero, Silvia Frosini, Valentina Lanzillotta, Giulia Colia, Filippo Cavallaro, Enrica Rolle, Roberto De Sanctis, Nicola Forcina, Roberta Petillo, Andrea Barp, Alice Gardani, Antonella Pini, Giulia Monaco, Maria Grazia D'Angelo, Riccardo Zanin, Gian Luca Vita, Claudio Bruno, Tiziana Mongini, Federica Ricci, Elena Pegoraro, Luca Bello, Angela Berardinelli, Roberta Battini, Valeria Sansone, Emilio Albamonte, Giovanni Baranello, Enrico Bertini, Luisa Politano, Maria Pia Sormani, Eugenio Mercuri
The aim of the study was to establish 24 month changes in upper limb function using a revised version of the performance of upper limb test (PUL 2.0) in a large cohort of ambulant and non-ambulant boys with Duchenne muscular dystrophy and to identify possible trajectories of progression. Of the 187 patients studied, 87 were ambulant (age range: 7-15.8 years), and 90 non-ambulant (age range: 9.08-24.78). The total scores changed significantly over time (p<0.001). Non-ambulant patients had lower total scores at baseline (mean 19...
2018: PloS One
https://www.readbyqxmd.com/read/29924825/second-harmonic-generation-microscopy-provides-accurate-automated-staging-of-liver-fibrosis-in-patients-with-non-alcoholic-fatty-liver-disease
#15
Pik Eu Chang, George Boon Bee Goh, Wei Qiang Leow, Liang Shen, Kiat Hon Lim, Chee Kiat Tan
BACKGROUND: Assessment of severity of liver fibrosis is essential in the management of non-alcoholic fatty liver disease (NAFLD). Second Harmonic Generation (SHG) microscopy is a novel optical tissue imaging system that provides automated quantification of fibrosis based on unique architectural features of collagen. This study aims to develop and validate a SHG-based index for automated staging of liver fibrosis in patients with NAFLD. METHODS: SHG microscopy was performed on archived liver biopsy specimens from 83 patients with NAFLD...
2018: PloS One
https://www.readbyqxmd.com/read/29924797/survival-and-nutritional-status-of-children-with-severe-acute-malnutrition-six-months-post-discharge-from-outpatient-treatment-in-jigawa-state-nigeria
#16
Collins John, Udochukwu Diala, Ruth Adah, Luret Lar, Esther Awazzi Envuladu, Idris Adedeji, Kazeem Lasisi, Oluseyi Olusunde, Femi James, Halima Abdu
BACKGROUND: The Outpatient Therapeutic Program (OTP) for treatment brings the management of Severe Acute Malnutrition (SAM) closer to the community. Many lives have been saved through this approach, but little data exists on the outcome of the children after discharge from such programmes. This study was aimed to determine the survival and nutritional status of children at six months after discharge from OTP for SAM. METHODOLOGY: This was a prospective study of children with SAM admitted into 10 OTPs in two local government areas of Jigawa state from June 2016 to July 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29924780/-temporary-tamponing-of-the-canal-while-removing-the-great-saphenous-vein-in-elderly-patients
#17
N G Khorev, A V Beller, V O Kon'kova, Ia N Shoĭkhet
The purpose of the study was to optimize the technique of removing the trunk of the great saphenous vein (GSV) in patients over 60 years. The study included a total of eighty-five patients aged over 60 years and presenting with primary varicose veins of the lower limbs and undergoing operations performed on the superficial venous system, including all stages of classical phlebectomy - crossectomy, stripping of the GSV, removal of tributaries and ligation of incompetent perforant veins. The patients were divided into two groups: the Study Group (n=44) patients endured removal of the GSV with the use of the technique of temporal tamponing of the canal, while in Group Two patients, composing a comparison group (n=41), the GSV was removed without the use of a tampon...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924779/-clinical-efficacy-of-detralex-in-treatment-of-women-with-pelvic-varicose-veins
#18
R V Akhmetzianov, R A Bredikhin
Presented herein are the results of using Detralex in conservative treatment of women suffering from pelvic varicose veins. Our open prospective study included a total of 30 women with various forms of the course of the disease. All patients took Detralex prescribed at a daily dose of 1,000 mg for 60 days. Dynamic assessment of clinical manifestations of pelvic varicose veins in this cohort of patients was carried out with the help of a specialized quality-of-life questionnaire, an adapted clinical scale of determining disease severity, as well as a visual analogue scale for assessment of the main symptoms of the disease manifestations...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924776/-results-of-endovascular-treatment-of-obstructive-lesions-of-veins-of-the-iliofemoral-segment
#19
A V Pokrovskiĭ, I M Ignat'ev, E G Gradusov
OBJECTIVE: The purpose of the study was to assess the immediate and remote results of endovascular treatment of obstructive lesions of the veins of the iliofemoral segment. PATIENTS AND METHODS: We performed balloon angioplasty and stenting for iliofemoral venous thrombosis in a total of 75 patients. Of these, 60 patients were subjected to stenting of post-thrombotic obstructions and 15 patients underwent stenting of non-thrombotic obstructive lesions of the iliac veins (for May-Thurner syndrome - in 11, for extravasal tumour-induced compression and cicatricial stenosis - in 4)...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924773/-gene-mediated-induction-of-angiogenesis-in-inoperable-patients-with-atherosclerosis-and-diabetes-mellitus
#20
R E Kalinin, I A Suchkov, R V Deev, N D Mzhavanadze, A A Krylov
Analysed in the article are the results of a comprehensive approach to treatment of patients presenting with lower limb critical ischaemia and diabetes mellitus by means of gene-induced angiogenesis. The study comprised a total of 65 patients found to have an ill-suited for surgical reconstruction peripheral arterial bed and undergoing conservative therapy. The patients were divided into two groups. The Study Group patients additionally to the conventional conservative therapy received 2 intramuscular injections of therapeutic agent Neovasculgen at a course dose of 2...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
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