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https://www.readbyqxmd.com/read/29773199/health-risk-assessment-of-arsenic-in-realgar-and-niuhuangjiedu-tablets-based-on-pharmacokinetic-study
#1
Xiao Wu, Shanhu Wu, Yuexin Liu, Rong Guan, Fangmei Liang, Min Song, Taijun Hang
NiuHuangJieDu Tablets (NHJDT), a popular realgar (As4 S4 ) containing patented traditional Chinese medicine (TCM), is widely used in the treatment of acute tonsillitis, pharyngitis, periodontitis and mouth ulcer. However, arsenic is considered as one of the most toxic elements, leading to growing concerns about the quality and safety of realgar-containing TCMs recently. In this study, health risk assessment of arsenic in realgar and NHJDT was conducted through oral administration of both substances to rats with single and multiple doses, respectively...
July 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29767829/homeopathy-in-the-age-of-antimicrobial-resistance-is-it-a-viable-treatment-for-upper-respiratory-tract-infections
#2
Alison Fixsen
BACKGROUND:  Acute upper respiratory tract infections (URTIs) and their complications are the most frequent cause of antibiotic prescribing in primary care. With multi-resistant organisms proliferating, appropriate alternative treatments to these conditions are urgently required. Homeopathy presents one solution; however, there are many methods of homeopathic prescribing. This review of the literature considers firstly whether homeopathy offers a viable alternative therapeutic solution for acute URTIs and their complications, and secondly how such homeopathic intervention might take place...
May 2018: Homeopathy: the Journal of the Faculty of Homeopathy
https://www.readbyqxmd.com/read/29758228/differences-in-swallow-physiology-in-patients-with-left-and-right-hemispheric-strokes
#3
Janina Wilmskoetter, Bonnie Martin-Harris, William G Pearson, Leonardo Bonilha, Jordan J Elm, Janet Horn, Heather S Bonilha
BACKGROUND: We sought to determine the impact of lesion lateralization and lesion volume on swallow impairment on group-level by comparing patients with left and right hemisphere strokes and on patient-level by analyzing patients individually. METHODS: We performed a retrospective, observational, cross-sectional study of 46 patients with unilateral (22 left, 24 right), acute, first-ever, ischemic strokes who received a diffusion weighted MRI (DW-MRI) and modified barium swallow study (MBSS) during their acute hospital stay...
May 11, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29754963/predictors-of-a-drainable-suppurative-adenitis-among-children-presenting-with-cervical-adenopathy
#4
Amir A Kimia, Tiffany F Rudloe, Nadine Aprahamian, Jennifer McNamara, David Roberson, Assaf Landschaft, Jennifer Vaughn, Marvin B Harper
OBJECTIVES: We sought to identify predictors for a drainable suppurative adenitis [DSA] among patients presenting with acute cervical lymphadenitis. METHODS: A retrospective cross sectional study of all patients admitted to an urban pediatric tertiary care emergency department over a 15 year period. Otherwise healthy patients who underwent imaging for an evaluation of cervical lymphadenitis were included. Cases were identified using a text-search module followed by manual review...
May 5, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29736223/the-effect-of-swallowing-rehabilitation-on-quality-of-life-of-the-dysphagic-patients-with-cortical-ischemic-stroke
#5
Kadir Bahcecı, Ebru Umay, Ibrahim Gundogdu, Eda Gurcay, Erhan Ozturk, Sibel Alıcura
Background: Swallowing and swallowing-related quality of life studies following stroke were almost always performed by including both patients with brainstem and cortical involvement. It was aimed in this study to show the presence of dysphagia in patients with only cortical ischemic stroke and to investigate the interaction between dysphagia and quality of life as well as to evaluate the effect of a rehabilitation program in the acute phase. Methods: Seventy-two patients with cortical stroke (between 0 and 30 days) and dysphagia were included...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29735420/-post-streptococcal-glomerulonephritis-in-the-south-of-tunisia-a-12-year-retrospective-review
#6
Bayen Maalej, Mona Ben Amor, Manel Jallouli, Manel Weli, Mohamed Charfi, Yassine Abdelkefi, Olfa Chakroun, Khaoula Kamoun, Jamil Hachicha, Noureddine Rekik, Taher Gargah, Lamia Gargouri, Abdelmajid Mahfoudh
AIM: Post-streptococcal glomerulonephritis (PSGN) is a frequent cause of acute nephritis in children. This study aimed to describe the epidemiology, clinical characteristics and outcomes of PSGN and look for predictor's factors of severity. METHODS: A 12-year retrospective review of case notes and laboratory data was conducted at a department of pediatrics, pediatric emergency and intensive care, Hedi Chaker Hospital. RESULTS: One hundred seventy eight children were treated for PSGN with a mean age of 7...
May 4, 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29719037/provider-variation-in-antibiotic-prescribing-and-outcomes-of-respiratory-tract-infections
#7
Mahesh Manne, Abhishek Deshpande, Bo Hu, Aditi Patel, Glen B Taksler, Anita D Misra-Hebert, Stacey E Jolly, Andrei Brateanu, Robert W Bales, Michael B Rothberg
OBJECTIVES: Inappropriate antibiotic use for respiratory tract infection (RTI) is an ongoing problem linked to the emergence of drug resistance and other adverse effects. Less is known about the prescribing practices of individual physicians or the impact of physician prescribing habits on patient outcomes. We studied the prescribing practices of providers for acute RTIs in an integrated health system, identified patient factors associated with receipt of an antibiotic and assessed the relation between providers' adjusted prescribing rates and a number of patient outcomes...
April 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29713897/coordination-of-pharyngeal-and-laryngeal-swallowing-events-during-single-liquid-swallows-after-oral-endotracheal-intubation-for-patients-with-acute-respiratory-distress-syndrome
#8
Martin B Brodsky, Ishani De, Kalyan Chilukuri, Minxuan Huang, Jeffrey B Palmer, Dale M Needham
To evaluate timing and duration differences in airway protection and esophageal opening after oral intubation and mechanical ventilation for acute respiratory distress syndrome (ARDS) survivors versus age-matched healthy volunteers. Orally intubated adult (≥ 18 years old) patients receiving mechanical ventilation for ARDS were evaluated for swallowing impairments via a videofluoroscopic swallow study (VFSS) during usual care. Exclusion criteria were tracheostomy, neurological impairment, and head and neck cancer...
April 30, 2018: Dysphagia
https://www.readbyqxmd.com/read/29703016/a-case-report-of-life-threatening-acute-dysphagia-in-dermatomyositis-challenges-in-diagnosis-and-treatment
#9
Kyoung Min Kwon, Jung Soo Lee, Yeo Hyung Kim
RATIONALE: Although dysphagia is a known complication of dermatomyositis, sudden onset of dysphagia without the notable aggravation of other symptoms can make the diagnosis and treatment challenging. PATIENT CONCERNS: A 53-year-old male diagnosed as dermatomyositis 1 month ago came to our emergency department complaining of a sudden inability to swallow solid foods and liquids. The patient showed generalized edema, but the muscle power was not different compared with 1 month ago...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29698106/effects-of-morphine-on-respiratory-load-detection-load-magnitude-perception-and-tactile-sensation-in-obstructive-sleep-apnea
#10
Rodrigo Tomazini Martins, Jayne C Carberry, Simon C Gandevia, Jane E Butler, Danny J Eckert
Pharyngeal and respiratory sensation is impaired in obstructive sleep apnea (OSA). Opioids may further diminish respiratory sensation. Thus, protective pharyngeal neuromuscular and arousal responses to airway occlusion that rely on respiratory sensation could be impaired with opioids to worsen OSA severity. However, little is known about the effects of opioids on upper airway and respiratory sensation in people with OSA. This study was designed to determine the effects of 40mg of MS-Contin on tactile sensation, respiratory load detection and respiratory magnitude perception in people with OSA during wakefulness...
April 26, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29671499/poststreptococcal-illness-recognition-and-management
#11
David L Maness, Michael Martin, Gregg Mitchell
Group A beta-hemolytic streptococcus can cause several postinfectious, nonsuppurative immune- mediated diseases including acute rheumatic fever, poststreptococcal reactive arthritis, pediatric autoimmune neuropsychiatric disorders, and poststreptococcal glomerulonephritis. Except for sporadic outbreaks, poststreptococcal autoimmune syndromes occur most commonly in sub-Saharan Africa, India, Australia, and New Zealand. Children younger than three years are rarely affected by group A streptococcus pharyngitis or rheumatic fever, and usually do not require testing...
April 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29599804/metabolic-profiling-analysis-of-the-alleviation-effect-of-the-fractions-of-niuhuang-jiedu-tablet-on-realgar-induced-toxicity-in-rats
#12
Wenfeng Xu, Yuehu Pei, Shuo Xu, Haifeng Wang, Pengfei Jin
Niuhuang Jiedu Tablet (NJT) is a classical formula in treating acute tonsillitis, pharyngitis, and so on. In the formula, significant level of Realgar as a potentially toxic element is contained. Our previous experiments revealed that it was less toxic for combined Realgar in NJT. However, the active fraction of this prescription with toxicity alleviation effect on Realgar was still obscure. NJT was divided into five different polar fractions (NJT-PET, NJT-25, NJT-50, NJT-75, and NJT-95), and we explored the toxicity alleviation effect on Realgar ...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29595103/application-of-medicinal-plants-as-a-source-for-therapeutic-agents-against-streptococcus-pyogenes-infections
#13
Adil Mohd, H P Vasantha Rupasinghe
Streptococcus pyogenes, a major human pathogen, causes a wide variety of invasive systemic infections such as acute pharyngitis, skin and soft-tissue infections, especially necrotizing fasciitis. This Gram-positive bacterium has an ability to form mature biofilm and this sessile lifestyle plays an important role in S. pyogenes pathogenicity. The virulence of these bacteria is further strengthened by its ability to communicate within the micro-colonies through quorum sensing. Most treatments are now aimed at either elimination of this bacterium or suppression of its virulence...
March 29, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29564346/kawasaki-disease-among-egyptian-children-a-case-series
#14
Tarek Hamed Attia, Saed M Morsy, Bashier A Hassan, Al Shymaa A Ali
Kawasaki disease is an acute vasculitis of early childhood. Its incidence varies among different ethnic groups with higher rates among Asians. In this case series, we presented four cases of Kawasaki disease with incomplete or atypical presentations in Egyptian children. Two cases presented with meningitis, which is not a criteria for the diagnosis of Kawasaki disease. The other two cases presented with pharyngitis and fever, which did not respond to antibiotics. The clinical criteria for diagnosis of Kawasaki disease were either incomplete or appeared sequentially...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29561517/the-impact-of-clinical-pathways-on-antibiotic-prescribing-for-acute-otitis-media-and-pharyngitis-in-the-emergency-department
#15
Daniele Dona, Maura Baraldi, Giulia Brigadoi, Rebecca Lundin, Giorgio Perilongo, Rana F Hamdy, Theoklis Zaoutis, Liviana Da Dalt, Carlo Giaquinto
BACKGROUND: Although Italian pediatric antimicrobial prescription rates are among the highest in Europe, little action has been taken to improve the appropriateness of antimicrobial prescriptions. The primary aim of this study was to assess changes in antibiotic prescription before and after acute otitis media (AOM) and group A streptococcus (GAS) pharyngitis Clinical Pathway (CP) implementation; secondary aims were to compare treatment failures and to assess change in the total antibiotics costs before and after CP implementation...
March 14, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29559880/acute-calcific-tendonitis-of-the-longus-colli
#16
Blake S Raggio, Samuel C Ficenec, Jason Pou, Brian Moore
Background: Acute calcific tendonitis of the longus colli (ACTLC) is an aseptic inflammatory response to deposition of calcium in the longus colli muscle tendons. Although reports in the literature are scarce, ACTLC likely represents an underreported disease process that routinely goes misdiagnosed. We report a case of ACTLC and provide a brief review of the literature. Case Report: A 45-year-old otherwise healthy female presented with a 3-day history of progressive neck pain, decreased neck mobility, and odynophagia...
2018: Ochsner Journal
https://www.readbyqxmd.com/read/29554121/group-a-streptococcus-pharyngitis-and-pharyngeal-carriage-a-meta-analysis
#17
Jane Oliver, Erandi Malliya Wadu, Nevil Pierse, Nicole J Moreland, Deborah A Williamson, Michael G Baker
OBJECTIVE: Antibiotic treatment of Group A Streptococcus (GAS) pharyngitis is important in acute rheumatic fever (ARF) prevention, however clinical guidelines for prescription vary. GAS carriers with acute viral infections may receive antibiotics unnecessarily. This review assessed the prevalence of GAS pharyngitis and carriage in different settings. METHODS: A random-effects meta-analysis was performed. Prevalence estimates for GAS+ve pharyngitis, serologically-confirmed GAS pharyngitis and asymptomatic pharyngeal carriage were generated...
March 19, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29533349/a-clear-cut-case-of-acute-rheumatic-fever-after-group-g-streptococcal-pharyngitis-in-new-zealand
#18
Diana Lennon
No abstract text is available yet for this article.
April 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29530660/streptococcal-pharyngitis-and-rheumatic-heart-disease-the-superantigen-hypothesis-revisited
#19
REVIEW
Jacklyn R Hurst, Katherine J Kasper, Akshay N Sule, John K McCormick
Streptococcus pyogenes is a human-specific and globally prominent bacterial pathogen that despite causing numerous human infections, this bacterium is normally found in an asymptomatic carrier state. This review provides an overview of both bacterial and human factors that likely play an important role in nasopharyngeal colonization and pharyngitis, as well as the development of acute rheumatic fever and rheumatic heart disease. Here we highlight a recently described role for bacterial superantigens in promoting acute nasopharyngeal infection, and discuss how these immune system activating toxins could be crucial to initiate the autoimmune process in rheumatic heart disease...
July 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29523424/clinical-mimics-an-emergency-medicine-focused-review-of-streptococcal-pharyngitis-mimics
#20
Michael Gottlieb, Brit Long, Alex Koyfman
BACKGROUND: Pharyngitis is a common disease in the emergency department (ED). Despite a relatively low incidence of complications, there are many dangerous conditions that can mimic this disease and are essential for the emergency physician to consider. OBJECTIVE: This article provides a review of the evaluation and management of group A β-hemolytic Streptococcal (GABHS) pharyngitis, as well as important medical conditions that can mimic this disease. DISCUSSION: GABHS pharyngitis often presents with fever, sore throat, tonsillar exudates, and anterior cervical lymphadenopathy...
May 2018: Journal of Emergency Medicine
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