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Acute pharyngitis

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https://www.readbyqxmd.com/read/28030530/hostage-to-history-the-duration-of-antimicrobial-treatment-for-acute-streptococcal-pharyngitis
#1
Michael Radetsky
Oral antimicrobial treatment of acute streptococcal pharyngitis commonly is given for 10 days. An investigation was conducted of journal publications and textbooks from the dawn of the antimicrobial era to the present in order to discover the basis for this settled practice. Current treatment duration for acute streptococcal pharyngitis was established half a century ago under conditions significantly different from those currently encountered by the average clinician. The 10-day treatment standard evolved without scientific justification...
December 27, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28024718/patterns-of-dysphagia-and-acute-toxicities-in-patients-with-head-and-neck-cancer-undergoing-helical-imrt%C3%A2-concurrent-chemotherapy
#2
Laura B Moroney, Jennifer Helios, Elizabeth C Ward, Jane Crombie, Leesa F Wockner, Clare L Burns, Ann-Louise Spurgin, Claire Blake, Lizbeth Kenny, Brett G M Hughes
BACKGROUND: There is limited prospective data reporting the extent of treatment related toxicities associated with helical Intensity Modulated Radiotherapy (H-IMRT) for head and neck cancer (HNC). The study aim was to investigate severity, peak incidence and recovery patterns of dysphagia and related toxicities in patients undergoing H-IMRT±chemotherapy to examine when patients are experiencing symptoms requiring supportive clinical care. METHODS: Prospective study of 212 patients undergoing H-IMRT...
January 2017: Oral Oncology
https://www.readbyqxmd.com/read/28004797/acute-transcriptional-up-regulation-specific-to-osteoblasts-osteoclasts-in-medaka-fish-immediately-after-exposure-to-microgravity
#3
Masahiro Chatani, Hiroya Morimoto, Kazuhiro Takeyama, Akiko Mantoku, Naoki Tanigawa, Koji Kubota, Hiromi Suzuki, Satoko Uchida, Fumiaki Tanigaki, Masaki Shirakawa, Oleg Gusev, Vladimir Sychev, Yoshiro Takano, Takehiko Itoh, Akira Kudo
Bone loss is a serious problem in spaceflight; however, the initial action of microgravity has not been identified. To examine this action, we performed live-imaging of animals during a space mission followed by transcriptome analysis using medaka transgenic lines expressing osteoblast and osteoclast-specific promoter-driven GFP and DsRed. In live-imaging for osteoblasts, the intensity of osterix- or osteocalcin-DsRed fluorescence in pharyngeal bones was significantly enhanced 1 day after launch; and this enhancement continued for 8 or 5 days...
December 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27989256/junctional-tachycardia-in-a-child-with-non-rheumatic-fever-streptococcal-pharyngitis
#4
Neha Bansal, Peter P Karpawich, Chenni S Sriram
Accelerated junctional rhythm has been reported in children in the setting of acute rheumatic fever; however, we describe a hitherto unreported case of isolated junctional tachycardia in a child with streptococcal pharyngitis, not meeting revised Jones criteria for rheumatic fever. A previously healthy, 9-year-old girl presented to the emergency department with complaints of sore throat, low-grade fever, and intermittent chest pain. She was found to have a positive rapid streptococcal antigen test. The initial electrocardiogram showed junctional tachycardia with atrioventricular dissociation in addition to prolonged and aberrant atrioventricular conduction...
December 19, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27981538/diagnosis-and-treatment-of-acute-pharyngitis-tonsillitis-a-preliminary-observational-study-in-general-medicine
#5
F Di Muzio, M Barucco, F Guerriero
OBJECTIVE: According to recent observations, the insufficiently targeted use of antibiotics is creating increasingly resistant bacterial strains. In this context, it seems increasingly clear the need to resort to extreme and prudent rationalization of antibiotic therapy, especially by the physicians working in primary care units. In clinical practice, actually the general practitioner often treats multiple diseases without having the proper equipment. In particular, the use of a dedicated, easy to use diagnostic test would be one more weapon for the correct diagnosis and treatment of acute pharyngo-tonsillitis...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27978460/clinical-characteristics-of-headache-or-facial-pain-prior-to-the-development-of-acute-herpes-zoster-of-the-head
#6
Hye Lim Lee, Minju Yeo, Gi Hwa Choi, Ji Yeoun Lee, Ji Seon Kim, Dong-Ick Shin, Sang-Soo Lee, Sung-Hyun Lee
OBJECTIVES: When physicians encounter patients with headache or facial pain (preeruptive pain) associated with acute herpes zoster of the head, especially before the appearance of characteristic skin eruptions (preeruptive phase), they typically find it difficult to make clinical impressions and apply appropriate diagnostic or therapeutic procedures. The objectives of this study were to describe the clinical characteristics of headache or facial pain associated with acute herpes zoster of the head and to elucidate the association between the manifestation of these symptoms in the preeruptive phase and incoming herpes zoster...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27956842/role-of-a-proprietary-propolis-based-product-on-the-wait-and-see-approach-in-acute-otitis-media-and-in-preventing-evolution-to-tracheitis-bronchitis-or-rhinosinusitis-from-nonstreptococcal-pharyngitis
#7
Francesco Di Pierro, Alberto Zanvit, Maria Colombo
Antipyretics and/or anti-inflammatory drugs along with a wait-and-see approach are the only treatments recommended in early acute otitis media (AOM) or viral pharyngitis. Propolis has been widely investigated for its antibacterial, antiviral, and anti-inflammatory properties and could perhaps be administered as an add-on therapy during watchful waiting in AOM or for better control of symptoms in nonstreptococcal pharyngitis. However, propolis has well-known problems of poor solubility and low oral bioavailability...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27940505/a-previously-healthy-adolescent-with-acute-encephalopathy-and-decorticate-posturing
#8
Yu Kawai, Andrea G DeMonbrun, Rebecca S Chambers, Danielle A Nolan, Bram A Dolcourt, Nasuh M Malas, Michael W Quasney
A 14-year-old previously healthy female was transferred from a local emergency department after being found unresponsive at home. Parental questioning revealed she had fever and pharyngitis 2 weeks before presentation. Past mental health history was negative, including concern for past or present suicidal ideation/attempts, suspected substance use, or toxic ingestion. In the emergency department, she was orotracheally intubated due to a Glasgow Coma Scale of 3. She was hemodynamically stable and euglycemic...
January 2017: Pediatrics
https://www.readbyqxmd.com/read/27939516/nonrheumatic-myopericarditis-post-acute-streptococcal-pharyngitis-an-uncommon-cause-of-sore-throat-with-st-segment-elevation
#9
Ali Pourmand, Daniel Gelman, Steven Davis, Hamid Shokoohi
Nonrheumatic myopericarditis is an uncommon complication of acute pharyngitis caused by Group A Streptococcal infection (GAS). While the natural history of carditis complicating acute rheumatic fever is well established, the incidence, pathophysiology and clinical course of nonrheumatic myopericarditis are ill defined. Advances in rapid bedside testing for both myocardial injury and GAS pharyngitis have allowed for increasing recognition of this uncommon complication in patients presenting with a sore throat with associated chest discomfort...
December 8, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27920580/positive-clinical-outcomes-derived-from-using-streptococcus-salivarius-k12-to-prevent-streptococcal-pharyngotonsillitis-in-children-a-pilot-investigation
#10
Francesco Di Pierro, Maria Colombo, Alberto Zanvit, Amilcare S Rottoli
BACKGROUND: Streptococcus salivarius K12 (BLIS K12(®)) is a probiotic strain producing the bacteriocins salivaricin A2 and salivaricin B, both of which strongly antagonize the growth of Streptococcus pyogenes, the most important bacterial cause of pharyngeal infections in humans. It successfully colonizes and exhibits persistence in the oral cavity and is endowed with an excellent safety profile. Previous observations of a small group of children indicated that the use of BLIS K12 could also reduce the occurrence of viral pharyngitis...
2016: Drug, Healthcare and Patient Safety
https://www.readbyqxmd.com/read/27912214/common-cold-an-umbrella-term-for-acute-infections-of-nose-throat-larynx-and-bronchi
#11
P Kardos, F A Malek
Acute respiratory tract infections, i. e. rhinitis, sinusitis, pharyngitis, laryngitis, bronchitis, belong to the most common medical conditions with a high economic burden. Nonetheless, there is little agreement concerning their differential diagnosis.This paper will discuss to what extent different anatomical sites of acute respiratory tract infections can be uniquely identified or whether the overlap and consecutive development in signs and symptoms renders these distinctions meaningless.Acute respiratory tract infections are variable but definition of diagnostic categories based on the anatomical sites of the dominant complaints shows that signs and symptoms both overlap to a great extent and/or emerge successively...
December 2, 2016: Pneumologie
https://www.readbyqxmd.com/read/27904957/neck-pain-and-acute-dysphagia
#12
João Simões, José Romão, Anita Cunha, Sofia Paiva, António Miguéis
The acute tendinitis of the longus colli muscle is an unusual diagnosis in the cases of acute dysphagia with cervical pain. Is a self-limiting condition caused by abnormal calcium hydroxyapatite deposition in the prevertebral space and can cause pharyngeal swelling with impaired swallow. It is absolutely critical to make the differential diagnosis with deep cervical infections in order to avoid invasive treatments.
November 30, 2016: Dysphagia
https://www.readbyqxmd.com/read/27902646/macrolide-and-clindamycin-resistance-in-group-a-streptococci-isolated-from-children-with-pharyngitis
#13
Gregory P DeMuri, Alana K Sterkel, Phillip A Kubica, Megan N Duster, Kurt D Reed, Ellen R Wald
Group A streptococcus (GAS) is responsible for 15-30% of cases of acute pharyngitis in children. Macrolides such as azithromycin have become popular for treating GAS pharyngitis. We report macrolide resistance rates in a primary care setting in our geographic area over the past 5 years and discuss the implications of resistance in making treatment decisions. Throat swabs were collected from children with pharyngitis from May 2011 to May 2015 in a primary care setting in Madison, WI. Susceptibility testing was performed for erythromycin and clindamycin using the Kirby-Bauer disk diffusion method...
November 28, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27898687/effects-of-chronologic-age-and-young-child-exposure-on-respiratory-syncytial-virus-disease-among-us-preterm-infants-born-at-32-to-35-weeks-gestation
#14
Eric A F Simões, Evan J Anderson, Xionghua Wu, Christopher S Ambrose
OBJECTIVE: To estimate the incidence of respiratory syncytial virus (RSV) disease as a function of chronologic age and exposure to young children in US preterm infants. METHODS: In the RSV Respiratory Events among Preterm Infants Outcomes and Risk Tracking (REPORT) study, preterm infants born at 32-35 weeks gestational age (wGA) were enrolled from 188 US clinics and followed September-May of 2009-2010 or 2010-2011. Infants with medically-attended acute respiratory illness had nasal/pharyngeal swabs collected for viral testing...
2016: PloS One
https://www.readbyqxmd.com/read/27884793/sex-stress-and-sleep-apnoea-decreased-susceptibility-to-upper-airway-muscle-dysfunction-following-intermittent-hypoxia-in-females
#15
REVIEW
Ken D O'Halloran, Philip Lewis, Fiona McDonald
Obstructive sleep apnoea syndrome (OSAS) is a devastating respiratory control disorder more common in men than women. The reasons for the sex difference in prevalence are multifactorial, but are partly attributable to protective effects of oestrogen. Indeed, OSAS prevalence increases in post-menopausal women. OSAS is characterized by repeated occlusions of the pharyngeal airway during sleep. Dysfunction of the upper airway muscles controlling airway calibre and collapsibility is implicated in the pathophysiology of OSAS, and sex differences in the neuro-mechanical control of upper airway patency are described...
November 21, 2016: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27874935/effect-of-administration-of-streptococcus-salivarius-k12-on-the-occurrence-of-streptococcal-pharyngo-tonsillitis-scarlet-fever-and-acute-otitis-media-in-3-years-old-children
#16
F Di Pierro, M Colombo, M G Giuliani, M L Danza, I Basile, T Bollani, A M Conti, A Zanvit, A S Rottoli
OBJECTIVE: Streptococcus salivarius K12 (BLIS K12) is a probiotic strain strongly antagonistic to the growth of Streptococcus pyogenes, the most important bacterial cause of pharyngeal infections in humans. Shown to colonize the oral cavity and to be safe for human use, BLIS K12 has previously been reported to reduce pharyngo-tonsillitis episodes in children or adults known to have experienced recurrent streptococcal infection. The present study was focussed upon evaluating the role of BLIS K12 in the control of streptococcal disease and acute otitis media in children attending the first year of kindergarten...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27847520/a-complicated-course-of-acute-viral-induced-pharyngitis-icteric-hepatitis-acalculous-cholecystitis-and-skin-rash
#17
Fereshte Sheybani, HamidReza Naderi, Seddigheh Sadat Erfani, Masoumeh Gharib
This case reveals the complexities and challenges in the diagnosis of acute Epstein-Barr virus (EBV) infection, indicating the potential relationship between EBV infection and severe icteric hepatitis, acalculous cholecystitis, and lymphocytic vasculitis. We suggest including EBV infectious mononucleosis in the list of differential diagnoses when any of these clinical syndromes (or a combination thereof) occurs without apparent cause, especially in the presence of lymphocytosis. To our knowledge, this is the first report to suggest the possible role of EBV in the pathogenesis of cutaneous lymphocytic vasculitis...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27845834/variation-in-quality-of-care-among-virtual-urgent-care-providers
#18
Yash M Patel
Key findings. (1) Significant variation in quality was found among companies providing virtual visits for management of common acute illnesses. (2) Variation in the performance of the telemedicine companies differed by condition. Specifically, variation across websites was significantly greater for viral pharyngitis and acute rhinosinusitis than for streptococcal pharyngitis, low back pain, ankle pain, and recurrent urinary tract infection. (3) Mode of communication (videoconference, telephone, or webchat) had no statistically significant effect on completeness of history and physical examination or adherence to key management decision guidelines...
September 2016: Findings Brief: Health Care Financing & Organization
https://www.readbyqxmd.com/read/27833453/benign-acute-childhood-myositis-complicating-influenza-b-infection-in-a-boy-with-idiopathic-nephrotic-syndrome
#19
Piotr Skrzypczyk, Joanna Przychodzień, Małgorzata Pańczyk-Tomaszewska
INTRODUCTION: Benign acute childhood myositis (BACM) is an acute complication of an infection characterized by calf pain, limitation of lower limb mobility, an increase in serum creatine kinase, and a self-limiting course. No reports of BACM in children with idiopathic nephrotic syndrome (INS) can be found in the literature. CASE REPORT: A 5-year-old boy with steroid-sensitive INS presented with fever, leg pain, and problems with walking. Physical examination showed pharyngeal erythema, preserved movements in all joints, and weakness of leg muscles...
2016: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/27821851/phenotypic-differentiation-of-streptococcus-pyogenes-populations-is-induced-by-recombination-driven-gene-specific-sweeps
#20
Yun-Juan Bao, B Jesse Shapiro, Shaun W Lee, Victoria A Ploplis, Francis J Castellino
Genomic recombination plays an important role in driving adaptive evolution and population differentiation in bacteria. However, controversy exists as to the effects of recombination on population diversity and differentiation, i.e., recombination is frequent enough to sweep through the population at selected gene loci (gene-specific sweeps), or the recombination rate is low without interfering genome-wide selective sweeps. Observations supporting either view are sparse. Pathogenic bacteria causing infectious diseases are promising candidates to provide observations of recombination...
November 8, 2016: Scientific Reports
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