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type 2 respiratory failure

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https://www.readbyqxmd.com/read/29769138/geographic-distribution-and-molecular-analysis-of-porcine-reproductive-and-respiratory-syndrome-viruses-circulating-in-swine-farms-in-the-republic-of-korea-between-2013-and-2016
#1
Hyeonjeong Kang, Ji Eun Yu, Ji-Eun Shin, Areum Kang, Won-Il Kim, Changhee Lee, Jienny Lee, In-Soo Cho, Se-Eun Choe, Sang-Ho Cha
BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) causes devastating disease characterized by reproductive failure and respiratory problems in the swine industry. To understand the recent prevalence and genetic diversity of field PRRSVs in the Republic of Korea, open reading frames (ORFs) 5 and 7 of PRRSV field isolates from 631 PRRS-affected swine farms nationwide in 2013-2016 were analyzed along with 200 Korean field viruses isolated in 2003-2010, and 113 foreign field and vaccine strains...
May 16, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29764707/mid-term-outcomes-from-a-multicenter-study-is-tevar-safe-for-ascending-aortic-dissection
#2
Qingsheng Lu, Lei Liu, Guangqi Chang, Xueming Chen, Hai Feng, Xuemin Zhang, Weiguo Fu, Zhihui Dong, Zaiping Jing
OBJECTIVES: This study aims to report mid-term follow-up outcomes of a series of TAAD patients treated with TEVAR in China. BACKGROUND: Thoracic endovascular aortic repair (TEVAR) has been used to treat type A aortic dissection (TAAD) for years. However, by comparing public reports, their outcomes which were based on different sample sizes show inconsistency. METHODS: Between January 2001 and December 2015, there were 56 patients with TAAD received TEVAR identified in 5 medical centers...
May 2, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29761677/pleural-fluid-b-type-natriuretic-peptide-level-as-an-additional-indicator-for-the-fluid-s-etiology
#3
Ronen Zalts, Tomer Twizer, Ronit Leiba, Amir Karban
BACKGROUND: The identification of the etiology of a pleural effusion can be difficult. Measurement of serum B-type natriuretic peptide (BNP) levels is helpful in the diagnosis of congestive heart failure (CHF) as a cause of respiratory failure, but pleural fluid BNP measurement is still not part of the workup for pleural effusion. OBJECTIVES: To identify the correlation between pleural fluid BNP levels and clinical diagnosis. METHODS: In this cross-sectional study, data from 107 patients admitted to the department of internal medicine between November 2009 and January 2015 were obtained from medical records...
May 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29761130/spinal-muscular-atrophy-with-respiratory-distress-type-1-a-child-with-atypical-presentation
#4
Annie Ting Gee Chiu, Sophelia Hoi Shan Chan, Shun Ping Wu, Shun Hin Ting, Brian Hon Yin Chung, Angel On Kei Chan, Virginia Chun Nei Wong
The authors report a child with spinal muscular atrophy with respiratory distress type 1 (SMARD1). She presented atypically with hypothyroidism and heart failure due to septal defects that required early heart surgery and microcephaly in association with cerebral atrophy and thin corpus collosum. The subsequent asymmetrical onset of diaphragmatic paralysis, persistent hypotonia, and generalized muscle weakness led to the suspicion of spinal muscular atrophy with respiratory distress type 1. Sanger sequencing confirmed a compound heterozygous mutation in the Immunoglobulin Mu Binding Protein 2 (IGHMBP2) gene, with a known mutation c...
2018: Child Neurology Open
https://www.readbyqxmd.com/read/29743771/cervical-myelopathy-in-a-child-a-rare-cause-of-hypoventilation-syndrome-presenting-with-type-2-respiratory-failure
#5
Alolika Mondal, Prabhas Prasun Giri
Hypoventilation syndrome leading to Type 2 respiratory failure is not a rare cause of Pediatric Intensive Care Unit admission and mechanical ventilation. Common causes in pediatric population are Guillain-Barre syndrome and various central nervous system disorders such as encephalitis, traumatic brain injury, and drugs. Any injury or disease in the cervical cord can also produce respiratory paralysis causing respiratory failure. Here, we present two cases of mixed cerebral palsy with cervical myelopathy due to compression effect of fractured segments of first and second cervical vertebrae...
April 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29737017/pediatric-acute-respiratory-distress-syndrome-associated-with-human-metapneumovirus-and-respiratory-syncytial-virus
#6
Thyyar M Ravindranath, Amanda Gomez, Ilana Harwayne-Gidansky, Thomas J Connors, Nathan Neill, Bruce Levin, Joy D Howell, Lisa Saiman, John S Baird
OBJECTIVES: To study the incidence, risk factors, clinical course, and outcome of ARDS in children with HMP and RSV. WORKING HYPOTHESIS: We hypothesized that ARDS in children with HMP was similar in incidence, risk factors, clinical course, and outcomes to ARDS in children with RSV. STUDY DESIGN: Retrospective, observational study over 2 years. PATIENT-SUBJECT SELECTION: Patients included were <18 years old with HMP or RSV detected from nasopharyngeal specimens by commercial reverse transcriptase polymerase chain reaction assay admitted to a study site...
May 7, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29730308/in-vitro-and-in-silico-studies-reveal-capsid-mutant-porcine-circovirus-2b-with-novel-cytopathogenic-and-structural-characteristics
#7
Taís Fukuta Cruz, Angelo José Magro, Alessandra M M G de Castro, Francisco J Pedraza-Ordoñez, Miriam Harumi Tsunemi, David Perahia, João Pessoa Araújo
Porcine circovirus 2 (PCV2) is an icosahedral, non-enveloped, and single-stranded circular DNA virus that belongs to the family Circoviridae, genus Circovirus, and is responsible for a complex of different diseases defined as porcine circovirus diseases (PCVDs). These diseases - including postweaning multisystemic wasting syndrome (PMWS), enteric disease, respiratory disease, porcine dermatitis and nephropathy syndrome (PDNS), and reproductive failure - are responsible for large economic losses in the pig industry...
May 3, 2018: Virus Research
https://www.readbyqxmd.com/read/29680792/-pneumocystis-jiroveci-pneumonia-in-a-patient-taking-benepali-for-rheumatoid-arthritis
#8
Kay Frances Graham, Anne McEntegart
We present a case of a 57-year-old woman who contracted Pneumocystis jiroveci pneumonia while on Benepali, the biosimilar version of etanercept for rheumatoid arthritis. She had seropositive erosive disease. She was admitted to clinic with a 2-week history of dyspnoea, dry cough and fever. Her initial examination showed her to be hypoxic on air with saturations of 77% and left basal crackles. Her admission chest X-ray showed fine reticular shadowing, with an initial suspicion of pulmonary fibrosis. She was empirically treated for community-acquired pneumonia but continued to deteriorate with a worsening type 1 respiratory failure...
April 21, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29674395/bilateral-tension-pneumothorax-after-acupuncture
#9
Nurashikin Mohammad
Acupuncture is an ancient complementary medicine which is currently used worldwide. Many serious adverse events have been reported which include a spectrum of mild-to-fatal complications. However, the level of awareness with regard to complications is still low both to physicians and patients. We report a 63-year-old who presented with acute shortness of breath 2 hours after having had acupuncture. On examination, there was absent breath sound heard on the left lung and slightly reduced breath sound on the right lung...
April 19, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29673298/initial-clinical-experience-using-the-low-profile-altura-endograft-system-with-double-d-shaped-proximal-stents-for-endovascular-aneurysm-repair
#10
Dainis Krievins, Albrecht Krämer, Janis Savlovskis, Georgij Oszkinis, E Sebastian Debus, Alexander Oberhuber, Christopher K Zarins
PURPOSE: To report the initial clinical results of endovascular aneurysm repair (EVAR) using the low-profile (14-F) Altura Endograft System, which features a double "D-shaped" stent design with suprarenal fixation and modular iliac components that are deployed from distal to proximal. METHODS: From 2011 to 2015, 90 patients (mean age 72.8±8.3 years; 79 men) with abdominal aortic aneurysm (AAA; mean diameter 53.8±5.7 mm) were treated at 10 clinical sites in 2 prospective, controlled clinical studies using the Altura endograft...
April 1, 2018: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29659630/body-mass-index-of-92-027-patients-acutely-admitted-to-general-hospitals-in-denmark-associated-clinical-characteristics-and-30-day-mortality
#11
Sigrid Bjerge Gribsholt, Lars Pedersen, Bjørn Richelsen, Olaf Dekkers, Reimar Wernich Thomsen
BACKGROUND: Data are sparse on the range of BMI among patients acutely admitted to general hospitals. We investigated BMI values and associated patient characteristics, reasons for hospital admission, and mortality in Denmark. METHODS: We identified all persons with an acute inpatient admission 2011-2014 in Central Denmark Region and assessed BMI measurements recorded in the Clinical Information System. We used cross-sectional and cohort analyses to examine the BMI distribution and its association with demographic characteristics, comorbidities, medication use, tobacco smoking, reasons for admission, and 30-day mortality...
2018: PloS One
https://www.readbyqxmd.com/read/29651298/true-or-false-coral-snake-is-it-worth-the-risk-a-micrurus-corallinus-case-report
#12
Marcelo Abrahão Strauch, Guilherme Jones Souza, Jordana Nahar Pereira, Tyelli Dos Santos Ramos, Marcelo Oliveira Cesar, Marcelo Amorim Tomaz, Marcos Monteiro-Machado, Fernando Chagas Patrão-Neto, Paulo A Melo
Background: Bites provoked by the genus Micrurus represent less than 1% of snakebite cases notified in Brazil, a tiny fraction compared with other genus such as Bothrops and Crotalus , which together represent almost 80% of accidents. In addition to their less aggressive behavior, habits and morphology of coral snakes are determinant factors for such low incidence of accidents. Although Micrurus bites are rare, victims must be rescued and hospitalized in a short period of time, because this type of envenoming may evolve to a progressive muscle weakness and acute respiratory failure...
2018: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/29622508/identifying-novel-phenotypes-of-acute-heart-failure-using-cluster-analysis-of-clinical-variables
#13
Yu Horiuchi, Shuzou Tanimoto, A H M Mahbub Latif, Kevin Y Urayama, Jiro Aoki, Kazuyuki Yahagi, Taishi Okuno, Yu Sato, Tetsu Tanaka, Keita Koseki, Kota Komiyama, Hiroyoshi Nakajima, Kazuhiro Hara, Kengo Tanabe
BACKGROUND: Acute heart failure (AHF) is a heterogeneous disease caused by various cardiovascular (CV) pathophysiology and multiple non-CV comorbidities. We aimed to identify clinically important subgroups to improve our understanding of the pathophysiology of AHF and inform clinical decision-making. METHODS: We evaluated detailed clinical data of 345 consecutive AHF patients using non-hierarchical cluster analysis of 77 variables, including age, sex, HF etiology, comorbidities, physical findings, laboratory data, electrocardiogram, echocardiogram and treatment during hospitalization...
March 29, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29621258/diva-metabolomics-differentiating-vaccination-status-following-viral-challenge-using-metabolomic-profiles
#14
Darren W Gray, Michael D Welsh, Fawad Mansoor, Simon Doherty, Olivier P Chevallier, Christopher T Elliott, Mark H Mooney
Bovine Respiratory Disease (BRD) is a major source of economic loss within the agricultural industry. Vaccination against BRD-associated viruses does not offer complete immune protection and vaccine failure animals present potential routes for disease spread. Serological differentiation of infected from vaccinated animals (DIVA) is possible using antigen-deleted vaccines, but during virus outbreaks DIVA responses are masked by wild-type virus preventing accurate serodiagnosis. Previous work by the authors has established the potential for metabolomic profiling to reveal metabolites associated with systemic immune responses to vaccination...
2018: PloS One
https://www.readbyqxmd.com/read/29621128/can-teamwork-and-high-volume-experience-overcome-challenges-of-lymphadenectomy-in-morbidly-obese-patients-body-mass-index-of-40-kg-m2-or-greater-with-endometrial-cancer-a-cohort-study-of-robotics-and-laparotomy-and-review-of-literature
#15
Hubert Fornalik, Temeka Zore, Nicole Fornalik, Todd Foster, Adrian Katschke, Gary Wright
OBJECTIVE: This study aimed to compare surgical outcomes and the adequacy of surgical staging in morbidly obese women with a body mass index (BMI) of 40 kg/m or greater who underwent robotic surgery or laparotomy for the staging of endometrioid-type endometrial cancer. METHODS: This is a retrospective cohort study of patients who underwent surgical staging between May 2011 and June 2014. Patients' demographics, surgical outcomes, intraoperative and postoperative complications, and pathological outcomes were compared...
April 4, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29619932/mortality-and-morbidity-in-patients-with-osteogenesis-imperfecta-in-denmark
#16
Lars Folkestad
Ostegenesis imperfecta (OI) is a hereditary disease of the connective tissue caused by mutations to, mainly, the genes that are involved in the biosynthesis of collagen type 1. Patients are grouped according to clinical severity and mode of inheritance according to Sillence's classification (originally 1979, updated 2014). According to our data, the population prevalence of OI in Denmark was 10.3 per 100,000, with 575 patients registered with an OI diagnosis in the National Patient Register and alive at the end of 2012 out of a total population of 5,602,628 persons...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29619334/factors-determining-outcomes-in-adult-patient-undergoing-mechanical-ventilation-a-real-world-retrospective-study-in-an-indian-intensive-care-unit
#17
Khalid Ismail Khatib, Subhal Bhalchandra Dixit, Mukund Manohar Joshi
Background: Characteristics of patients admitted to intensive care units with respiratory failure (RF) and undergoing mechanical ventilation (MV) have been described for particular indications and diseases, but there are few studies in the general Intensive Care Unit (ICU) population and even lesser from developing countries. Objective: This study aims to study clinical characteristics, outcomes, and factors affecting outcomes in adult patients with RF on MV admitted to ICU...
January 2018: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29606865/long-term-oxygen-therapy-in-copd-patients-population-based-cohort-study-on-mortality
#18
Nikolay Pavlov, Alan Gary Haynes, Armin Stucki, Peter Jüni, Sebastian Robert Ott
Purpose: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide and is associated with a growing and substantial socioeconomic burden. Long-term oxygen therapy (LTOT), recommended by current treatment guidelines for COPD patients with severe chronic hypoxemia, has shown to reduce mortality in this population. The aim of our study was to assess the standardized mortality ratios of incident and prevalent LTOT users and to identify predictors of mortality...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29576405/a-propensity-matched-comparison-of-fenestrated-endovascular-aneurysm-repair-and-open-surgical-repair-of-pararenal-and-paravisceral-aortic-aneurysms
#19
Giovanni Tinelli, Maria Antonietta Crea, Chiara de Waure, Gian Luca Di Tanna, Jean-Pierre Becquemin, Jonathan Sobocinski, Francesco Snider, Stéphan Haulon
OBJECTIVE: This study investigated the outcomes of a current series of patients treated with fenestrated and branched endovascular aneurysm repair (F-BEVAR) or open surgical repair (OSR) for pararenal abdominal aortic aneurysms (pr-AAAs), including juxtarenal, suprarenal, and type IV thoracoabdominal aneurysms. This study compares the outcomes of these procedures from two high-volume centers without the bias induced by a learning curve. METHODS: All patients with pr-AAAs undergoing repair at two centers between January 2010 and June 2016 were included in a prospective database...
March 22, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29575095/spinal-muscular-atrophy-with-respiratory-distress-type-1-associated-with-novel-compound-heterozygous-mutations-in-ighmbp2-differential-diagnosis-in-a-case-with-congenital-diaphragm-eventration
#20
Yoshitomo Yasui, Hitoshi Sato, Yo Niida, Miyuki Kohno
Spinal muscular atrophy with respiratory distress type 1 (SMARD1, OMIM #604320) is a rare motor neuron disease caused by autosomal recessive mutations in the immunoglobulin mu binding protein 2 (IGHMBP2) gene (Grohmann 2001). SMARD1 is characterized by respiratory failure requiring mechanical ventilation, initial distal and later generalized muscular weakness, and autonomic nerve dysfunction (Eckart 2015).
March 24, 2018: Congenital Anomalies
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