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Anastomotic leak colon

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https://www.readbyqxmd.com/read/29341151/gut-microbiome-influences-on-anastomotic-leak-and-recurrence-rates-following-colorectal-cancer-surgery
#1
REVIEW
S Gaines, C Shao, N Hyman, J C Alverdy
BACKGROUND: The pathogenesis of colorectal cancer recurrence after a curative resection remains poorly understood. A yet-to-be accounted for variable is the composition and function of the microbiome adjacent to the tumour and its influence on the margins of resection following surgery. METHODS: PubMed was searched for historical as well as current manuscripts dated between 1970 and 2017 using the following keywords: 'colorectal cancer recurrence', 'microbiome', 'anastomotic leak', 'anastomotic failure' and 'mechanical bowel preparation'...
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29327167/does-laparoscopic-intracorporeal-ileocolic-anastomosis-decreases-surgical-site-infection-rate-a-propensity-score-matched-cohort-study
#2
L Martinek, K You, S Giuratrabocchetta, M Gachabayov, K Lee, R Bergamaschi
AIM: Foreshortened mesentery or thick abdominal wall constitutes a rationale for laparoscopic intracorporeal ileocolic anastomoses (ICA). The aim of this study was to compare intracorporeal to extracorporeal ICA in terms of surgical site infections in patients with Crohn's ileitis and overweight patients with right colon tumors. METHOD: This was a prospective propensity score-matched cohort study enrolling consecutive patients with Crohn's terminal ileitis and overweight patients with right colon tumors undergoing elective laparoscopic right colon resection with intracorporeal or extracorporeal ICA...
January 11, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29321843/esophagocoloplasty-fistula-successfully-treated-with-vacuum-assisted-closure
#3
Santiago A Endara, Fernando J Terán, Armando J Serrano, Manuela J Castillo, Gabriel A Molina
Esophageal fistulas in the cervical region are usually difficult to manage and carry a high morbidity. We report a case of an esophago-colonic fistula after colonic interposition, successfully managed with vacuum-assisted closure 'V.A.C. system', (Kinetic Concepts Inc., San Antonio, TX, USA). The patient initially presented with purulent fluid from the cervical wound 13 days after surgery. Esophagogram confirmed a leak. Since the patient had a history of anastomotic leaks, a surgical intervention was not the treatment of choice...
January 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29280120/-clinical-application-of-compound-anastomotic-device-in-protective-terminal-ileostomy-during-rectal-cancer-operation
#4
Qi Huang, Feng Cao, Jinzhe Zhou, Liming Liu, Bujun Ge
OBJECTIVE: To investigate the clinical effect of the application of "compound anastomotic device" on the high-risk colorectal anastomosis in rectal cancer patients undergoing protective ileostomy. METHODS: A total of 116 rectal cancer patients undergoing surgical procedure and prophylactic ileostomy in Tongji Hospital (90 cases) and The Third People's Hospital of Jingdezhen City (26 cases) from May 2011 to October 2016 were prospectively enrolled in the study. Paralleled control study and random digital table were applied...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29273871/using-outcomes-data-to-justify-instituting-new-technology-a-single-institution-s-experience
#5
P M Starker, B Chinn
BACKGROUND: The PILLAR II trial demonstrated PINPOINT is safe, feasible to use with no reported adverse events and resulted in no anastomotic leaks in patients who had a change in surgical plan based on PINPOINT's intraoperative assessment of tissue perfusion during colorectal resection. Whether the cost savings associated with this reduction in anastomotic complications can offset the cost of investing in PINPOINT is unknown. METHODS: We performed a retrospective analysis of all patients (N = 347) undergoing colectomy with primary anastomosis from January 2015 to April 2016...
December 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29229151/ketorolac-use-may-increase-risk-of-postoperative-pancreatic-fistula-after-pancreaticoduodenectomy
#6
Stacy J Kowalsky, Mazen S Zenati, Jennifer Steve, Kenneth K Lee, Melissa E Hogg, Herbert J Zeh, Amer H Zureikat
BACKGROUND: Ketorolac (Toradol), a commonly used nonselective nonsteroidal anti-inflammatory drug (NSAID) in the postoperative period, has been associated with increased risk of anastomotic leak after colon resection. The effect of postoperative NSAID and ketorolac use on postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is unknown. METHODS: Retrospective review of consecutive PDs at a high-volume pancreas center from 2012 to 2015. POPF was identified and graded using International Study Group on Pancreatic Fistula criteria...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29225732/laparoscopic-complete-mesocolic-excisions-for-colonic-cancer-in-the-last-decade-five-year-survival-in-a-single-centre
#7
Kristian Eeg Storli, Kristin Bentung Lygre, Knut Børge Iversen, Maria Decap, Geir Egil Eide
AIM: To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision (CME) for colonic cancer over a 10-year period. METHODS: Consecutive patients who received laparoscopic CME at our hospital from 2007 to 2017 were prospectively registered and retrospectively analysed. In total, 341 patients were included with tumour-nodal-metastasis (TNM) stages 0-III. RESULTS: The mean age of the patients was 71.9 years...
November 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29218671/robotic-versus-laparoscopic-right-colectomy-an-updated-systematic-review-and-meta-analysis
#8
Leonardo Solaini, Francesca Bazzocchi, Davide Cavaliere, Andrea Avanzolini, Alessandro Cucchetti, Giorgio Ercolani
BACKGROUND: In the right colon surgery, there is a growing literature comparing the safety of robotic right colectomy (RRC) to that of laparoscopic right colectomy (LRC). With this paper we aim to systematically revise and meta-analyze the latest comparative studies on these two minimally invasive procedures. METHODS: A systematic review of studies published from 2000 to 2017 in the PubMed, Scopus, and Embase databases was performed. Primary endpoints were postoperative morbidity and mortality...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29217909/predictive-factors-for-small-intestinal-and-colonic-anastomotic-leak-a-multivariate-analysis
#9
Ahmad Sakr, Sameh Hany Emile, Emad Abdallah, Waleed Thabet, Wael Khafagy
Anastomotic leak (AL) is a serious complication of intestinal surgery with various predisposing factors. This study aims to assess several risk factors associated with AL after small intestinal and colonic anastomoses through a multivariate analysis. Two hundred twenty-four patients (126 males) with intestinal anastomosis of a median age of 44 years were reviewed. Independent factors associated with AL were male gender (OR = 2.59, P = 0.02), chronic liver disease (CLD) (OR = 8.03, P < 0.0001), more than one associated comorbidity (OR = 5...
December 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29198768/combination-oral-and-mechanical-bowel-preparations-decreases-complications-in-both-right-and-left-colectomy
#10
Emily F Midura, Andrew D Jung, Dennis J Hanseman, Vikrom Dhar, Shimul A Shah, Janice F Rafferty, Bradley R Davis, Ian M Paquette
BACKGROUND: Before elective colectomy, many advocate mechanical bowel preparation with oral antibiotics, whereas enhanced recovery pathways avoid mechanical bowel preparations. The optimal preparation for right versus left colectomy is also unclear. We sought to determine which strategy for bowel preparation decreases surgical site infection (SSI) and anastomotic leak (AL). METHODS: Elective colectomies from the National Surgical Quality Improvement Program colectomy database (2012-2015) were divided by (1) type of bowel preparation: no preparation (NP), mechanical preparation (MP), oral antibiotics (PO), or mechanical and oral antibiotics (PO/MP); and (2) type of colonic resection: right, left, or segmental colectomy...
November 30, 2017: Surgery
https://www.readbyqxmd.com/read/29178125/laparoscopic-versus-open-resection-for-sigmoid-diverticulitis
#11
REVIEW
Iosief Abraha, Gian A Binda, Alessandro Montedori, Alberto Arezzo, Roberto Cirocchi
BACKGROUND: Diverticular disease is a common condition in Western industrialised countries. Most individuals remain asymptomatic throughout life; however, 25% experience acute diverticulitis. The standard treatment for acute diverticulitis is open surgery. Laparoscopic surgery - a minimal-access procedure - offers an alternative approach to open surgery, as it is characterised by reduced operative stress that may translate into shorter hospitalisation and more rapid recovery, as well as improved quality of life...
November 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29113714/laparoscopic-versus-open-colectomy-for-obstructing-right-colon-cancer-a-systematic-review-and-meta-analysis
#12
R Cirocchi, F Cesare Campanile, S Di Saverio, G Popivanov, L Carlini, D Pironi, R Tabola, N Vettoretto
BACKGROUND: Hemicolectomy is the treatment of choice for intestinal obstruction from right colon cancer. This review compares the laparoscopic vs open access in hemicolectomy for patients with right colon cancer. METHODS: A systematic review and meta-analysis of clinical studies published after January 2017 was performed according to the Prisma guidelines. The study has been recorded on the Prospero register (CRD42016044108). RESULTS: Five studies were included for review...
November 4, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/29106320/near-infrared-fluorescence-imaging-for-real-time-intraoperative-guidance-in-anastomotic-colorectal-surgery-a-systematic-review-of-literature
#13
Jacqueline van den Bos, Mahdi Al-Taher, Rutger M Schols, Sander van Kuijk, Nicole D Bouvy, Laurents P S Stassen
PURPOSE: The aims of this review are to determine the feasibility of near-infrared fluorescence (NIRF) angiography in anastomotic colorectal surgery and to determine the effectiveness of the technique in improving imaging and quantification of vascularization, thereby aiding in decision making as to where to establish the anastomosis. METHODS: A systematic literature search of PubMed and EMBASE was conducted. Searching through the reference lists of selected articles identified additional studies...
November 6, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29080956/validation-of-an-online-risk-calculator-for-the-prediction-of-anastomotic-leak-after-colon-cancer-surgery-and-preliminary-exploration-of-artificial-intelligence-based-analytics
#14
T Sammour, L Cohen, A I Karunatillake, M Lewis, M J Lawrence, A Hunter, J W Moore, M L Thomas
BACKGROUND: Recently published data support the use of a web-based risk calculator ( www.anastomoticleak.com ) for the prediction of anastomotic leak after colectomy. The aim of this study was to externally validate this calculator on a larger dataset. METHODS: Consecutive adult patients undergoing elective or emergency colectomy for colon cancer at a single institution over a 9-year period were identified using the Binational Colorectal Cancer Audit database. Patients with a rectosigmoid cancer, an R2 resection, or a diverting ostomy were excluded...
October 28, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29064902/the-role-of-bowel-preparation-in-colorectal-surgery-results-of-the-2012-2015-acs-nsqip-data
#15
Aaron L Klinger, Heather Green, Dominique J Monlezun, David Beck, Brian Kann, Herschel D Vargas, Charles Whitlow, David Margolin
OBJECTIVE: To analyze potential benefits with regards to infectious complications with combined use of mechanical bowel preparation (MBP) and ABP in elective colorectal resections. BACKGROUND: Despite recent literature suggesting that MBP does not reduce infection rate, it still is commonly used. The use of oral antibiotic bowel preparation (ABP) has been practiced for decades but its use is also controversial. METHODS: Patients undergoing elective colorectal resection in the 2012 to 2015 American College of Surgeons National Surgical Quality Improvement Program cohorts were selected...
October 23, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29049477/association-of-the-addition-of-oral-antibiotics-to-mechanical-bowel-preparation-for-left-colon-and-rectal-cancer-resections-with-reduction-of-surgical-site-infections
#16
Elaine Vo, Nader N Massarweh, Christy Y Chai, Hop S Tran Cao, Nader Zamani, Sherry Abraham, Kafayat Adigun, Samir S Awad
Importance: Surgical site infections (SSIs) after colorectal surgery remain a significant complication, particularly for patients with cancer, because they can delay the administration of adjuvant therapy. A combination of oral antibiotics and mechanical bowel preparation (MBP) is a potential, yet controversial, SSI prevention strategy. Objective: To determine the association of the addition of oral antibiotics to MBP with preventing SSIs in left colon and rectal cancer resections and its association with the timely administration of adjuvant therapy...
October 18, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28930958/perioperative-use-of-nonsteroidal-anti-inflammatory-drugs-and-the-risk-of-anastomotic-failure-in-emergency-general-surgery
#17
Nadeem N Haddad, Brandon R Bruns, Toby M Enniss, David Turay, Joseph V Sakran, Alisan Fathalizadeh, Kristen Arnold, Jason S Murry, Matthew M Carrick, Matthew C Hernandez, Margaret H Lauerman, Asad J Choudhry, David S Morris, Jose J Diaz, Herb A Phelan, Martin D Zielinski
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used analgesic and anti-inflammatory adjuncts. Nonsteroidal anti-inflammatory drug administration may potentially increase the risk of postoperative gastrointestinal anastomotic failure (AF). We aim to determine if perioperative NSAID utilization influences gastrointestinal AF in emergency general surgery (EGS) patients undergoing gastrointestinal resection and anastomosis. METHODS: Post hoc analysis of a multi-institutional prospectively collected database was performed...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28919097/j-pouch-vs-side-to-end-anastomosis-after-hand-assisted-laparoscopic-low-anterior-resection-for-rectal-cancer-a-prospective-randomized-trial-on-short-and-long-term-outcomes-including-life-quality-and-functional-results
#18
Nuri Okkabaz, Mustafa Haksal, Ali Emre Atici, Yunus Emre Altuntas, Ersin Gundogan, Fazli Cem Gezen, Mustafa Oncel
PURPOSE: To analyze the outcomes of j-pouch and side-to-end anastomosis in rectal cancer patients treated with laparoscopic hand-assisted low anterior resection. METHODS: Prospective trial on cases randomized to have a colonic j-pouch or a side-to-end anastomosis after low anterior resection. Demographics, characteristics of disease and treatment, perioperative results, and functional outcomes and life quality were compared between the groups. RESULTS: Seventy four patients were randomized...
November 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28916858/an-endoscopic-mucosal-grading-system-is-predictive-of-leak-in-stapled-rectal-anastomoses
#19
Sarath Sujatha-Bhaskar, Mehraneh D Jafari, Mark Hanna, Christina Y Koh, Colette S Inaba, Steven D Mills, Joseph C Carmichael, Ninh T Nguyen, Michael J Stamos, Alessio Pigazzi
BACKGROUND: Anastomotic leak is a devastating postoperative complication following rectal anastomoses associated with significant clinical and oncological implications. As a result, there is a need for novel intraoperative methods that will help predict anastomotic leak. METHODS: From 2011 to 2014, patient undergoing rectal anastomoses by colorectal surgeons at our institution underwent prospective application of intraoperative flexible endoscopy with mucosal grading...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28915206/laparoscopic-colorectal-surgery-in-patients-with-previous-abdominal-surgery-a-single-center-experience-and-literature-review
#20
Erdinc Kamer, Turan Acar, Fevzi Cengiz, Evren Durak, Mehmet Haciyanli
To present the outcomes of laparoscopic colorectal surgery in colorectal cancer patients with a previous history of abdominal surgery. Data of a total of 121 patients with primary colorectal cancer who underwent laparoscopic surgery were retrospectively analyzed. The patients were divided into 2 groups as those with previous abdominal surgery (PAS, n=34) and those without (non-PAS, n=87). Gastric and colonic surgeries were the most common procedures in the major PAS group, whereas gynecologic and obstetric surgeries and appendectomy were the most common procedures in the minor PAS group...
September 14, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
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