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https://www.readbyqxmd.com/read/28299431/changes-of-posterior-condylar-offset-results-in-midflexion-instability-in-single-radius-total-knee-arthroplasty
#1
Georg Matziolis, Steffen Brodt, Christoph Windisch, Eric Roehner
INTRODUCTION: There is no algorithm for the management of joint stability in midflexion up to now. Change in the joint line (JL) is considered to be the primary cause, although it only determines the extension gap. The purpose of this study was to determine the influence of the posterior condylar offsets (PCO), which defines the flexion gap, on midflexion instability. MATERIALS AND METHODS: Forty-two knee joints (38 patients) were included in this study, patients undergoing navigated total knee arthroplasty due to primary osteoarthritis of the knee...
March 16, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28295977/unexpected-photodegradation-of-a-phosphaketenyl-substituted-germyliumylidene-borate-complex
#2
Yun Xiong, Shenglai Yao, Tibor Szilvási, Ernesto Ballestero-Martínez, Hansjörg Grützmacher, Matthias Driess
The first zwitterionic borata-bis(NHC)-stabilized phosphaketenyl germyliumylidene [(L2 (O=C=P)Ge:] 2 (L2 =(p-tolyl)2 B[1-(1-adamantyl)-3-yl-2-ylidene]2 ) has been synthesized by salt-metathesis reaction of [L2 (Cl)Ge:] 1 with sodium phosphaethynolate [(dioxane)n NaOCP]. Unexpectedly, its exposure to UV light affords, after reductive elimination of the entire PCO group, the unprecedented [L2 Ge-GeL2 ] complex 3 in 54 % yields bearing the Ge2(2+) ion with Ge in the oxidation state +1. In addition, the 1,3-digermylium-2,4-diphosphacyclobutadiene [L2 Ge(μ-P)2 GeL2 ] 4 and bis(germyliumylidenyl)-substituted diphosphene [(L2 Ge-P=P-GeL2 )] 5 could also be obtained in moderate yields...
March 13, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28284038/3d-and-4d-studies-from-human-reproduction-to-perinatal-medicine
#3
Sonal Panchal, Asim Kurjak, Chaitanya Nagori
Three-dimensional ultrasound (3D US) is a modality of choice for prenatal diagnosis of congenital malformations. But 3D-four-dimensional US(4D US) is of utmost importance also to achieve pregnancy. 3D US plays an important role for diagnosis of PCO, to assess ovarian reserve and response and thus to decide optimum stimulation protocols. It adds to the information on follicular maturity and endometrial receptivity, thus improving the chances to achieve pregnancy for patients under treatment for fertility. 3D hystero-contrast-salpingography (HyCoSy) has also proved itself to be one of the best modalities for assessment of tubal patency...
March 11, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28282890/change-in-emiliania-huxleyi-virus-assemblage-diversity-but-not-in-host-genetic-composition-during-an-ocean-acidification-mesocosm-experiment
#4
Andrea Highfield, Ian Joint, Jack A Gilbert, Katharine J Crawfurd, Declan C Schroeder
Effects of elevated pCO₂ on Emiliania huxleyi genetic diversity and the viruses that infect E. huxleyi (EhVs) have been investigated in large volume enclosures in a Norwegian fjord. Triplicate enclosures were bubbled with air enriched with CO₂ to 760 ppmv whilst the other three enclosures were bubbled with air at ambient pCO₂; phytoplankton growth was initiated by the addition of nitrate and phosphate. E. huxleyi was the dominant coccolithophore in all enclosures, but no difference in genetic diversity, based on DGGE analysis using primers specific to the calcium binding protein gene (gpa) were detected in any of the treatments...
March 8, 2017: Viruses
https://www.readbyqxmd.com/read/28274761/developmental-toxicity-in-flounder-embryos-exposed-to-crude-oils-derived-from-different-geographical-regions
#5
Jee-Hyun Jung, Eun-Hee Lee, Kwang-Min Choi, Un Hyuk Yim, Sung Yong Ha, Joon Geon An, Moonkoo Kim
Crude oils from distinct geographical regions have distinct chemical compositions, and, as a result, their toxicity may be different. However, developmental toxicity of crude oils derived from different geographical regions has not been extensively characterized. In this study, flounder embryos were separately exposed to effluents contaminated by three crude oils including: Basrah Light (BLO), Pyrenees (PCO), and Sakhalin Vityaz (SVO), in addition to a processed fuel oil (MFO-380), to measure developmental toxicity and for gene expressions...
March 6, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28272309/determination-of-the-clean-air-delivery-rate-cadr-of-photocatalytic-oxidation-pco-purifiers-for-indoor-air-pollutants-using-a-closed-loop-reactor-part-ii-experimental-results
#6
Valérie Héquet, Frédéric Batault, Cécile Raillard, Frédéric Thévenet, Laurence Le Coq, Éric Dumont
The performances of a laboratory PhotoCatalytic Oxidation (PCO) device were determined using a recirculation closed-loop pilot reactor. The closed-loop system was modeled by associating equations related to two ideal reactors: a perfectly mixed reservoir with a volume of VR = 0.42 m³ and a plug flow system corresponding to the PCO device with a volume of VP = 5.6 × 10(-3) m³. The PCO device was composed of a pleated photocatalytic filter (1100 cm²) and two 18-W UVA fluorescent tubes. The Clean Air Delivery Rate (CADR) of the apparatus was measured under different operating conditions...
March 6, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28272308/determination-of-the-clean-air-delivery-rate-cadr-of-photocatalytic-oxidation-pco-purifiers-for-indoor-air-pollutants-using-a-closed-loop-reactor-part-i-theoretical-considerations
#7
Éric Dumont, Valérie Héquet
This study demonstrated that a laboratory-scale recirculation closed-loop reactor can be an efficient technique for the determination of the Clean Air Delivery Rate (CADR) of PhotoCatalytic Oxidation (PCO) air purification devices. The recirculation closed-loop reactor was modeled by associating equations related to two ideal reactors: one is a perfectly mixed reservoir and the other is a plug flow system corresponding to the PCO device itself. Based on the assumption that the ratio between the residence time in the PCO device and the residence time in the reservoir τP/τR tends to 0, the model highlights that a lab closed-loop reactor can be a suitable technique for the determination of the efficiency of PCO devices...
March 6, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28240001/polycystic-ovary-syndrome-pcos-diagnostic-criteria-and-amh
#8
Majid Bani Mohammad, Abbas Majdi Seghinsara
The polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and a notable proportion of women of reproductive age are affected. It may constitute a risk factor for cancer development. Different factors could result in different manifestations and many of these are related to predispositions. It is essential to establish criteria to achieve an exact diagnosis of PCOS, especially among adolescent patients because of the overlap between features of PCO syndrome and physiological findings in puberty...
January 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28228121/bleb-failure-and-intraocular-pressure-rise-following-nd-yag-laser-capsulotomy
#9
Andreas Diagourtas, Petros Petrou, Ilias Georgalas, Kostantinos Oikonomakis, Panagiotis Giannakouras, Athanasios Vergados, Dimitrios Papaconstantinou
BACKGROUND: To report the negative effect of Nd: Yag (Neodymium-doped: Yttrium Aluminium Garnet) laser capsulotomy on the intraocular pressure (IOP) and the trabeculectomy bleb integrity, in a small series of eyes, both trabeculectomised and pseudophakic, following the laser application for the management of posterior capsular opacification (PCO). METHODS: This is a retrospective, non-comparative interventional case series study, in which 20 trabeculectomised and pseudophakic eyes from 15 patients, with otherwise well functioning blebs, were presented with uncontrolled IOP, in a variable distance of time following the application of YAG laser capsulotomy...
February 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28209733/dual-function-of-tgf%C3%AE-in-lens-epithelial-cell-fate-implications-for-secondary-cataract
#10
Bruce A Boswell, Anna Korol, Judith A West-Mays, Linda S Musil
The most common vision-disrupting complication of cataract surgery is posterior capsule opacification (PCO; secondary cataract). PCO is caused by residual lens cells undergoing one of two very different cell fates: either transdifferentiating into myofibroblasts, or maturing into lens fiber cells. Although TGFβ has been strongly implicated in lens cell fibrosis, the factors responsible for the latter process have not been identified. We show here for the first time that TGFβ can induce purified primary lens epithelial cells within the same culture to undergo differentiation into either lens fiber cells or myofibroblasts...
February 16, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28208899/study-of-variation-in-intraocular-pressure-spike-iop-following-nd-yag-laser-capsulotomy
#11
Niharika K Shetty, Sriya Sridhar
INTRODUCTION: Posterior Capsular Opacifications (PCO) is a frequent complication of cataract surgery following posterior chamber intraocular lens implantation. Nd -Yag laser capsulotomy is the treatment of choice for PCO and is known to be associated with complications like Raised Intraocular Pressure (IOP), Intraocular lens pitting, intraocular lens cracks, cystoid macular oedema, retinal detachment, corneal burns. Raised IOP is the most common complication and prescribing anti-glaucoma drugs post capsulotomy is a common practise...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207414/anti-aging-effects-of-m2000-%C3%AE-d-mannuronic-acid-as-a-novel-immunosuppressive-drug-on-the-enzymatic-and-non-enzymatic-oxidative-stress-parameters-in-an-experimental-model
#12
Soma Hosseini, Mohammad Abdollahi, Gholamreza Azizi, Mohammad Javad Fattahi, Noshin Rastkari, Farzaneh Tofighi Zavareh, Zahra Aghazadeh, Abbas Mirshafiey
BACKGROUND: The anti-aging property of β-D-mannuronic acid (M2000) as a novel non-steroidal anti-inflammatory and immunosuppressive agent was investigated on several determinants relative to the oxidative stress in an animal model. MATERIALS AND METHODS: Sprague-Dawley rats were used for evaluating the safety and efficacy properties of M2000 on some oxidative stress enzymes, including the following: mitochondrial superoxide dismutase (SOD2), catalase (CAT), glutathione peroxidase (GPX1), glutathione S-transferase (GST), myeloperoxidase (MPO), and inducible nitric oxide synthase (iNOS) gene expression by real-time PCR...
February 16, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28195545/berberis-vulgaris-l-effects-on-oxidative-stress-and-liver-injury-in-lead-intoxicated-mice
#13
Jawhar Laamech, Jaouad El-Hilaly, Hamadi Fetoui, Yassine Chtourou, Hanane Gouitaa, Adel Tahraoui, Badiaa Lyoussi
Background Berberis vulgaris L. (BV), commonly known as "Aghriss" in Moroccan pharmacopoeia, is used to cure liver disorders and other diseases. The present study aimed to investigate the protective effect of BV aqueous extract against lead-induced toxicity in mice liver. Methods Sixty IOPS mice were divided into six groups and were treated as follows: group 1 (normal control) received double distilled water; group 2 (toxic control) received lead acetate (5 mg/kg body weight/day) in double distilled water for 40 days; groups 3-6 received BV aqueous extract at doses of 25, 50, 100 and 150 mg/kg body weight , respectively, once daily for 30 days from 11 day after beginning of lead acetate exposure to the end of the experiment...
March 1, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28179901/biochemical-molecular-and-transcriptional-highlights-of-the-biosynthesis-of-an-effective-biosurfactant-produced-by-bacillus-safensis-pha3-a-petroleum-dwelling-bacteria
#14
Abdulsamie Hanano, Mouhnad Shaban, Ibrahem Almousally
Petroleum crude oil (PCO)-dwelling microorganisms have exceptional biological capabilities to tolerate the toxicity of petroleum contaminants and are therefore promising emulsifier and/or degraders of PCO. This study describes a set of PCO-inhabiting bacterial species, one of which, identified as Bacillus safensis PHA3, produces an efficient biosurfactant which was characterized as a glycolipid. Fourier transform infrared spectrometer, nuclear magnetic resonance, Thin layer chromatography, HPLC, and GC-MS analysis of the purified biosurfactant revealed that the extracted molecule under investigation is likely a mannolipid molecule with a hydrophilic part as mannose and a hydrophobic part as hexadecanoic acid (C16:0)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28177683/olanzapine-alleviates-oxidative-stress-in-the-liver-of-socially-isolated-rats
#15
Andrijana Stanisavljevic, Ivana Peric, Marija Pantelic, Dragana M Filipovic
Olanzapine, an antipsychotic drug, is used to treat depressive disorder, but its effects on the liver, main site of drug metabolism, still remain elusive. We studied the effects of three weeks of olanzapine treatment (7.5 mg/kg/day) on the malondialdehyde (MDA) and protein carbonyl (PCO) contents, protein expression of copper/zinc superoxide dismutase (CuZnSOD) and activity of total superoxide dismutase (SOD) as well as catalase (CAT) protein expression/activity levels in the liver cytosol of rats exposed to six weeks of chronic social isolation (CSIS), that causes depressive- and anxiety-like behaviors...
December 22, 2016: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28177588/a-retrospective-study-of-isolated-fractures-of-the-alveolar-process-in-the-permanent-dentition
#16
Maja Marotti, Kurt Alois Ebeleseder, Gerold Schwantzer, Stefanie Jauk
BACKGROUND/AIM: There is a lack of studies of fractures of the alveolar process (FAP). Only five were published in the last fifty years. The aim of this study was to analyze the risk of pulp necrosis and infection (PN), pulp canal obliteration (PCO), infection-related root resorption (IRR), ankylosis-related resorption (ARR), marginal bone loss (MBL), and tooth loss (TL) as well as to identify the possible risk factors for teeth involved in an isolated alveolar process fracture. In the second part, any late complications of the involved teeth were reported in patients who responded to a follow-up examination...
February 8, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28165609/comparison-of-visual-outcomes-after-bilateral-implantation-of-extended-range-of-vision-and-trifocal-intraocular-lenses
#17
Ramón Ruiz-Mesa, Antonio Abengózar-Vela, Ana Aramburu, María Ruiz-Santos
PURPOSE: To compare visual outcomes after cataract surgery with bilateral implantation of 2 intraocular lenses (IOLs): extended range of vision and trifocal. METHODS: Each group of this prospective study comprised 40 eyes (20 patients). Phacoemulsification followed by bilateral implantation of a FineVision IOL (group 1) or a Symfony IOL (group 2) was performed. The following outcomes were assessed up to 1 year postoperatively: binocular uncorrected distance visual acuity (UDVA), binocular uncorrected intermediate visual acuity (UIVA) at 60 cm, binocular uncorrected near visual acuity (UNVA) at 40 cm, spherical equivalent (SE) refraction, defocus curves, mesopic and photopic contrast sensitivity, halometry, posterior capsule opacification (PCO), and responses to a patient questionnaire...
January 28, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28161922/a-prospective-evaluation-of-posterior-capsule-opacification-in-eyes-with-posterior-capsule-plaque-a-case-control-study
#18
Abhay R Vasavada, Mamidipudi R Praveen, Gauri D Shah, Kaid Johar, Rajkumar Sankaranarayanan
PURPOSE: To compare the development of posterior capsule opacification (PCO) between eyes with and without posterior capsule plaque after single-piece hydrophobic acrylic intraocular lens (IOL) implantation 5 years postoperatively. DESIGN: A prospective observational case-control study. METHODS: One hundred one consecutive eyes with posterior capsule plaque (cases) were compared with the same number of cataractous eyes without posterior capsule plaque (controls)...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28149310/the-effects-of-coenzyme-q10-supplementation-on-cardiometabolic-markers-in-overweight-type-2-diabetic-patients-with-stable-myocardial-infarction-a-randomized-double-blind-placebo-controlled-trial
#19
Seyyed Mehdi Mirhashemi, Vajiheh Najafi, Fariba Raygan, Zatollah Asemi
BACKGROUND: Limited data are present that have assessed the effects of coenzyme Q10 (CoQ10) intake on cardiometabolic markers in type 2 diabetic patients with coronary heart disease (CHD). This study was done to determine the effects of CoQ10 administration on cardiometabolic markers in overweight diabetic patients with stable myocardial infarction. METHODS: This randomized double-blind placebo-controlled clinical trial was done among 60 diabetic patients with CHD aged 45-75 years old...
July 2016: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/28137510/influence-of-aldose-reductase-on-epithelial-to-mesenchymal-transition-signaling-in-lens-epithelial-cells
#20
Kun-Che Chang, Biehuoy Shieh, J Mark Petrash
Cataract is the most frequent cause of blindness worldwide and is treated by surgical removal of the opaque lens to restore the light path to the retina. While cataract surgery is a safe procedure, some patients develop a complication of the surgery involving opacification and wrinkling of the posterior lens capsule. This process, called posterior capsule opacification (PCO), requires a second clinical treatment that can in turn lead to additional complications. Prevention of PCO is a current unmet need in the vision care enterprise...
January 27, 2017: Chemico-biological Interactions
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