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https://www.readbyqxmd.com/read/28102088/hyperandrogenism-in-a-postmenopausal-woman-a-rare-case-of-ectopic-adrenal-cortical-gland
#1
Antonella Guarino, Luisa Di Benedetto, Valentina Giovanale, Gian Luca Rampioni Vinciguerra, Antonella Stoppacciaro, Filippo Bellati, Donatella Caserta
Most frequent causes of androgenic manifestation are Cushing's syndrome, PCO, benign and malignant androgen-secreting non adrenal tumors and iatrogenic hirsutism. Hyperplasia or neoplasms of ectopic adrenocortical gland are rare. We report a case of a 63-year old female with hirsutism and alopecia. Laboratory data highlighted increased levels of androgens. Diagnostic imaging revealed normal morphology of adrenocortical gland and ovaries. In view of the clinical picture and suspected diagnosis of extra-adrenal cause, she underwent bilateral salpingo-oophorectomy...
January 19, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28101040/high-rate-of-early-posterior-capsule-opacification-following-femtosecond-laser-assisted-cataract-surgery
#2
Benjamin Rostami, Jack Tian, Nicholas Jackson, Rustum Karanjia, Kenneth Lu
PURPOSE: To compare the rates of rapid posterior capsule opacification (PCO) formation in the first 3 months following femtosecond laser-assisted cataract surgery (FLACS) to manual anterior capsulorhexis. METHODS: Retrospective review of 29 cases of FLACS, comparing the rates of PCO in the first 3 months following surgery to 50 consecutive cases of manual anterior capsulorhexis. RESULTS: Seven of the 29 FLACS cases developed PCO requiring capsulotomy at 3 months, while none of the control cases required a capsulotomy over the same time period (p < 0...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28100360/-end-tidal-pco-2-for-evaluation-of-severity-of-disease-in-idiopathic-pulmonary-arterial-hypertension-and-chronic-thromboembolic-pulmonary-hypertension
#3
X Shi, G L Yang, Y Chen, J Guo, W L Yang, P Yuan, S G Gong, R Jiang, Q H Zhao, L Wang, J He, T X Chen, J M Liu
Objective: To explore the difference in end tidal PCO(2) (P(ET)CO(2)) between idiopathic pulmonary arterial hypertension (IPAH) and chronic thromboembolic pulmonary hypertension (CTEPH), and to analyze the correlation between P(ET)CO(2) and the indexes of disease severity in IPAH and CTEPH patients. Methods: Data were retrieved from 68 IPAH patients and 52 CTEPH patients who all had received right-heart catheterization, pulmonary function test and cardiopulmonary exercise testing at Shanghai Pulmonary Hospital from October 2011 to October 2014...
January 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28096456/antibody-conjugated-dna-based-nanocarriers-intercalated-with-doxorubicin-eliminate-myofibroblasts-in-explants-of-human-lens-tissue
#4
Jacquelyn Gerhart, Marvin Greenbaum, Lou Casta, Anthony Clemente, Keith Mathers, Robert Getts, Mindy George-Weinstein
Posterior capsule opacification (PCO) occurs in some adults and most children following cataract surgery. The fibrotic form of PCO arises, in part, from migratory, contractile myofibroblasts that deform the lens capsule and impair vision. In short-term cultures of human anterior lens tissue, myofibroblasts emerge from Myo/Nog cells that are identified with the G8 monoclonal antibody and by their expression of the MyoD transcription factor and bone morphogenetic protein inhibitor noggin. In this study, we tested the hypothesis that targeted depletion of Myo/Nog cells with the G8 mAb conjugated to three-dimensional DNA nanocarriers intercalated with Doxorubicin (G8:3DNA:Dox) would prevent the accumulation of myofibroblasts in long-term, serum and growth factor free cultures of human lens tissue obtained by capsulorhexis...
January 17, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/28074798/proseal-laryngeal-mask-airway-as-an-alternative-to-standard-endotracheal-tube-in-securing-upper-airway-in-the-patients-undergoing-beating-heart-coronary-artery-bypass-grafting
#5
Kalpana Shah
BACKGROUND: ProSeal laryngeal mask airways (PLMAs) are routinely used after failed tracheal intubation as airway rescue, facilitating tracheal intubation by acting as a conduit and to secure airway during emergencies. In long duration surgeries, use of endotracheal tube (ETT) is associated with various hemodynamic complications, which are minimally affected during PLMA use. However, except for few studies, there are no significant data available that promote the use of laryngeal mask during cardiac surgery...
January 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28065623/an-anatomic-investigation-into-the-relationship-between-posterior-condylar-offset-and-posterior-tibial-slope-of-one-thousand-one-hundred-thirty-eight-cadaveric-knees
#6
Douglas S Weinberg, Jeremy J Gebhart, Glenn D Wera
BACKGROUND: Posterior condylar offset (PCO) and posterior tibial slope (PTS) have critical consequences in total knee arthroplasty, especially with regards to sagittal plane balancing. However, there has only been limited investigation into the functional consequences of each, and there have only been anecdotal observations regarding any associations between PCO and PTS. METHODS: In a large osteological study of 1138 knees, standardized measurements of PCO and PTS were taken using previously described techniques on specimens of different age, race, and gender...
December 22, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28065436/long-term-posterior-capsule-opacification-reduction-with-square-edge-polymethylmethacrylate-intraocular-lens-randomized-controlled-study
#7
Aravind Haripriya, David F Chang, Balakrishnan Vijayakumar, Agrawal Niraj, Madhu Shekhar, Singh Tanpreet, Srinivasan Aravind
PURPOSE: To objectively assess the long-term posterior capsule opacification (PCO) and neodymium-doped yttrium aluminium garnet (Nd:YAG) capsulotomy rate of a square-edge (SE) polymethylmethacrylate (PMMA) intraocular lens (IOL) modification in comparison with a round-edge (RE) PMMA IOL or an SE hydrophobic acrylic IOL (SE-Acrylic). DESIGN: Prospective, randomized, controlled fellow eye clinical study. PARTICIPANTS: Ninety-four patients scheduled for bilateral phacoemulsification had an SE-PMMA IOL implanted in 1 eye...
January 5, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28058161/posterior-capsular-opacification-in-preschool-and-school-age-patients-after-pediatric-cataract-surgery-without-posterior-capsulotomy
#8
Muhammed Batur, Adem Gül, Erbil Seven, Ertuğrul Can, Tekin Yaşar
OBJECTIVES: We aimed to evaluate the development of posterior capsular opacification (PCO) in preschool- and school-age children with cataract who underwent cataract surgery without posterior capsulotomy and anterior vitrectomy. MATERIALS AND METHODS: The records of 30 eyes of 21 patients who underwent pediatric cataract surgery and intraocular lens (IOL) implantation were retrospectively reviewed. Patients' age, PCO status and duration, need for neodymium-doped yttrium aluminium garnet (Nd:YAG) laser treatment based on coverage of visual axis, and follow-up period were recorded...
October 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28056020/travelling-wave-pulse-coupled-oscillator-twpco-using-a-self-organizing-scheme-for-energy-efficient-wireless-sensor-networks
#9
Zeyad Ghaleb Al-Mekhlafi, Zurina Mohd Hanapi, Mohamed Othman, Zuriati Ahmad Zukarnain
Recently, Pulse Coupled Oscillator (PCO)-based travelling waves have attracted substantial attention by researchers in wireless sensor network (WSN) synchronization. Because WSNs are generally artificial occurrences that mimic natural phenomena, the PCO utilizes firefly synchronization of attracting mating partners for modelling the WSN. However, given that sensor nodes are unable to receive messages while transmitting data packets (due to deafness), the PCO model may not be efficient for sensor network modelling...
2017: PloS One
https://www.readbyqxmd.com/read/28042549/relationship-between-il-17-serum-level-and-ambulatory-blood-pressure-in-women-with-polycystic-ovary-syndrome
#10
Fatemeh Foroozanfard, Alireza Soleimani, Elham Arbab, Mansooreh Samimi, Mohammad Reza Tamadon
BACKGROUND: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders with an inflammatory basis. It is associated with hyperandrogenism in women and can be also associated with increased activity of the renin-angiotensin system (RAS). Approximately 5% to 10% of women of reproductive age are affected by this disease. This syndrome is the main cause of infertility. Blood pressure may be one of the complications of the syndrome. OBJECTIVES: In this study, we sought to assess the role of the IL-17 inflammatory cytokine in increasing blood pressure in patients with PCOS...
January 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28040618/oxidative-damage-ultrastructural-alterations-and-gene-expressions-of-hemocytes-in-the-freshwater-crab-sinopotamon-henanense-exposed-to-cadmium
#11
Yanying Zhou, Weixin Jing, Hans-Uwe Dahms, Jiang-Shiou Hwang, Lan Wang
Toxicity of Cd was tested with the hemocytes of the freshwater crab, Sinopotamon henanense, which were exposed to concentrations of 0, 0.725, 1.450, and 2.900mgL(-1) Cd for 7, 14 and 21 d. We investigated the effects of Cd on the total antioxidant capacity (TAC), and oxidative damage of biomarkers, such as malondialdehyde (MDA), protein carbonyl derivates (PCO), and DNA-protein crosslink (DPC). Transmission electron microscopy (TEM) was applied to assess ultrastructural changes of hemocytes. The mRNA expression levels of prophenoloxidase (proPO), lysozyme (LSZ), metallothionein (MT), and the activity of phenoloxidase (PO) were also determined...
December 29, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28034065/integration-of-palliative-care-into-standard-oncology-care-american-society-of-clinical-oncology-clinical-practice-guideline-update
#12
Betty R Ferrell, Jennifer S Temel, Sarah Temin, Erin R Alesi, Tracy A Balboni, Ethan M Basch, Janice I Firn, Judith A Paice, Jeffrey M Peppercorn, Tanyanika Phillips, Ellen L Stovall, Camilla Zimmermann, Thomas J Smith
Purpose To provide evidence-based recommendations to oncology clinicians, patients, family and friend caregivers, and palliative care specialists to update the 2012 American Society of Clinical Oncology (ASCO) provisional clinical opinion (PCO) on the integration of palliative care into standard oncology care for all patients diagnosed with cancer. Methods ASCO convened an Expert Panel of members of the ASCO Ad Hoc Palliative Care Expert Panel to develop an update. The 2012 PCO was based on a review of a randomized controlled trial (RCT) by the National Cancer Institute Physicians Data Query and additional trials...
January 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28027493/hydrophilic-modification-of-intraocular-lens-via-surface-initiated-reversible-addition-fragmentation-chain-transfer-polymerization-for-reduced-posterior-capsular-opacification
#13
Quankui Lin, Junmei Tang, Yuemei Han, Xu Xu, Xiaojuan Hao, Hao Chen
Phacoemulsification followed with intraocular lens (IOL) implantation is the most effective clinical surgeries in treating cataracts. However, posterior capsular opacification (PCO), a common complication of this surgery, may cause vision decrease after surgery. PCO is mainly caused by the adhesion, proliferation and trans-differentiation of the residual lens epithelial cells (LEC) after surgery. Surface modification of IOL to reduce the LEC adhesion is of great importance in PCO prevention. Herein, surface initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization was utilized to modify the IOL materials for generating a comb-like polyethylene glycol (PEG) brush coating on the surface...
December 21, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28003789/an-after-after-cataract-a-curious-case-of-visual-axis-re-opacification
#14
Jay Kalliath, Gaurav Prakash, Kavitha Avadhani, Anitha Shakuntala
Posterior capsular opacification (PCO) is common after cataract surgery. Recurrence is very rare after a successful Yttrium aluminium-garnet (YAG) capsulotomy in adults. We report a case of visual axis re-opacification after a successful YAG capsulotomy for PCO in an adult. A 60-year male underwent phacoemulsification with +20.0 D acrylic hydrophobic intraocular lens implantation and silicon oil removal (SOR) five months after a successful retinal detachment repair. He underwent a capsulotomy after two months of surgery; however, the visual axis re-opacified after three more months...
October 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28001465/posterior-capsule-opacification-and-nd-yag-rates-with-two-acrylic-intraocular-lenses-after-age-related-cataract-treatment-three-year-results
#15
Miro Kalauz, Sanja Masnec, Rajko Kordić, Tomislav Kuzman, Sania Vidas, Ivan Škegro, Sonja Jandroković, Sanja Perić
OBJECTIVE: To compare the incidence and intensity of posterior capsule opacification (PCO) between two intraocular lenses (IOLs) over three years. METHODS: Eighty-three patients underwent cataract surgery with implantation of Acreos Adapt AO or Acrysof SA60AT. PCO values were assessed using a photographic image analysis system (EPCO 2000) and the amount of PCO at the slit lamp. RESULTS: Mean PCO score was 2.78 ± 1.55 for the Acreos Adapt AO and 2...
December 21, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27999581/melatonin-increases-the-chilling-tolerance-of-chloroplast-in-cucumber-seedlings-by-regulating-photosynthetic-electron-flux-and-the-ascorbate-glutathione-cycle
#16
Hailiang Zhao, Lin Ye, Yuping Wang, Xiaoting Zhou, Junwei Yang, Jiawei Wang, Kai Cao, Zhirong Zou
The aim of the study was to monitor the effects of exogenous melatonin on cucumber (Cucumis sativus L.) chloroplasts and explore the mechanisms through which it mitigates chilling stress. Under chilling stress, chloroplast structure was seriously damaged as a result of over-accumulation of reactive oxygen species (ROS), as evidenced by the high levels of superoxide anion (O2-) and hydrogen peroxide (H2O2). However, pretreatment with 200 μM melatonin effectively mitigated this by suppressing the levels of ROS in chloroplasts...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27998291/skeleton-based-cerebrovascular-quantitative-analysis
#17
Xingce Wang, Enhui Liu, Zhongke Wu, Feifei Zhai, Yi-Cheng Zhu, Wuyang Shui, Mingquan Zhou
BACKGROUND: Cerebrovascular disease is the most common cause of death worldwide, with millions of deaths annually. Interest is increasing toward understanding the geometric factors that influence cerebrovascular diseases, such as stroke. Cerebrovascular shape analyses are essential for the diagnosis and pathological identification of these conditions. The current study aimed to provide a stable and consistent methodology for quantitative Circle of Willis (CoW) analysis and to identify geometric changes in this structure...
December 20, 2016: BMC Medical Imaging
https://www.readbyqxmd.com/read/27976512/fgf2-antagonizes-aberrant-tgf%C3%AE-regulation-of-tropomyosin-role-for-posterior-capsule-opacity
#18
Eri Kubo, Shinsuke Shibata, Teppei Shibata, Etsuko Kiyokawa, Hiroshi Sasaki, Dhirendra P Singh
Transforming growth factor (TGF) β2 and fibroblast growth factor (FGF) 2 are involved in regulation of posterior capsule opacification (PCO) and other processes of epithelial-mesenchymal transition (EMT) such as cancer progression, wound healing and tissue fibrosis as well as normal embryonic development. We previously used an in vivo rodent PCO model to show the expression of tropomyosin (Tpm) 1/2 was aberrantly up-regulated in remodelling the actin cytoskeleton during EMT. In this in vitro study, we show the Tpms family of cytoskeleton proteins are involved in regulating and stabilizing actin microfilaments (F-actin) and are induced by TGFβ2 during EMT in lens epithelial cells (LECs)...
December 15, 2016: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/27956292/surgical-indications-outcomes-and-complications-with-the-use-of-a-modified-capsular-tension-ring-during-cataract-surgery
#19
Bo Li, Yongjun Wang, Monali S Malvankar-Mehta, Cindy M L Hutnik
PURPOSE: To determine the surgical indications, outcomes, and complications with the use of modified capsular tension rings (CTRs) during cataract surgery. SETTING: Ivey Eye Institute, Western University, London, Ontario, Canada. DESIGN: Systematic review. METHODS: A systematic review of databases was conducted for studies related to the use of modified CTRs during cataract surgery that were published between 1992 and 2015...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27956288/primary-posterior-capsulotomy-in-adults-with-posterior-capsule-opacification
#20
Haitham Younis Al-Nashar, Ahmad Saeed Khalil
PURPOSE: To evaluate the efficacy and safety of primary posterior continuous curvilinear capsulorhexis (PCCC) in adult patients with cataract. SETTING: Zagazig University Hospital, Ash-Sharkya, Egypt. DESIGN: Prospective nonrandomized case series. METHODS: This study comprised patients with senile cataract who had phacoemulsification. All patients had a dense posterior capsule opacification (PCO) discovered intraoperatively...
November 2016: Journal of Cataract and Refractive Surgery
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