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https://www.readbyqxmd.com/read/28645858/vascular-adaptation-pattern-formation-and-cross-validation-between-an-agent-based-model-and-a-dynamical-system
#1
Marc Garbey, Stefano Casarin, Scott A Berceli
Myocardial infarction is the global leading cause of mortality (Go AS et al. 2014). Coronary artery occlusion is its main etiology and it is commonly treated by Coronary Artery Bypass Graft (CABG) surgery (Wilson CT 2007). The long-term outcome remains unsatisfactory (Benedetto U 2016). The vein faces the phenomenon of restenosis during the post-surgery, which consists of re-occlusion of the lumen and usually requires secondary intervention even within one year after the initial surgery (Harskamp RE 2013). We propose an extensive study of the restenosis phenomenon by implementing two mathematical models previously developed: a heuristic Dynamical System (DS) (Garbey M and Berceli SA 2013), and a stochastic Agent Based Model (ABM) (Garbey M et al...
June 20, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28612504/effect-of-attention-bias-modification-on-brain-function-and-anxiety-in-patients-with-irritable-bowel-syndrome-a-preliminary-electroencephalogram-and-psycho-behavioral-study
#2
J Tayama, T Saigo, S Ogawa, A Takeoka, T Hamaguchi, M Hayashida, S Fukudo, S Shirabe
BACKGROUND: Gastrointestinal symptoms of irritable bowel syndrome (IBS) show a reciprocal relationship with anxiety. In this intervention-based study, we investigated the utility of attention bias modification (ABM) therapy in patients with IBS. We hypothesized that IBS-related electroencephalographic abnormalities would be normalized after ABM therapy. METHODS: Seventeen patients with IBS and 13 healthy subjects completed five ABM intervention sessions over a 2-month period...
June 14, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28595895/understanding-the-dissemination-of-appointment-based-synchronization-models-using-the-cfir-framework
#3
Julie Patterson, David Holdford
BACKGROUND: The appointment based model (ABM) is a innovative model of pharmacy practice that combines medication synchronization with scheduled monthly appointments to improve patient medication adherence and convenience. It is being implemented in many pharmacies across the United States. OBJECTIVE: The purpose of this article is to use the Consolidated Framework for Implementation Research (CFIR) to discuss the barriers and facilitators of ABM implementation in community pharmacies while identifying priorities for additional implementation research...
June 1, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28593562/assessing-the-impacts-of-the-changes-in-farming-systems-on-food-security-and-environmental-sustainability-of-a-chinese-rural-region-under-different-policy-scenarios-an-agent-based-model
#4
Chengcheng Yuan, Liming Liu, Xiaoxing Qi, Yonghu Fu, Jinwei Ye
Since China has undergone a series of economic reforms and implemented opening up policies, its farming systems have significantly changed and have dramatically influenced the society, economy, and environment of China. To assess the comprehensive impacts of these changes on food security and environmental sustainability, and establish effective and environment-friendly subsidy policies, this research constructed an agent-based model (ABM). Daligang Town, which is located in the two-season rice region of Southern China, was selected as the case study site...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28585809/bsim-2-0-an-advanced-agent-based-cell-simulator
#5
Antoni Matyjaszkiewicz, Gianfranco Fiore, Fabio Annunziata, Claire S Grierson, Nigel J Savery, Lucia Marucci, Mario di Bernardo
Agent-based models (ABMs) provide a number of advantages relative to traditional continuum modeling approaches, permitting incorporation of great detail and realism into simulations, allowing in silico tracking of single-cell behaviors and correlation of these with emergent effects at the macroscopic level. In this study we present BSim 2.0, a radically new version of BSim, a computational ABM framework for modeling dynamics of bacteria in typical experimental environments including microfluidic chemostats...
June 23, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28577533/an-agent-based-model-simulation-of-influenza-interactions-at-the-host-level-insight-into-the-influenza-related-burden-of-pneumococcal-infections
#6
Hélène Arduin, Matthieu Domenech de Cellès, Didier Guillemot, Laurence Watier, Lulla Opatowski
BACKGROUND: Host-level influenza virus-respiratory pathogen interactions are often reported. Although the exact biological mechanisms involved remain unelucidated, secondary bacterial infections are known to account for a large part of the influenza-associated burden, during seasonal and pandemic outbreaks. Those interactions probably impact the microorganisms' transmission dynamics and the influenza public health toll. Mathematical models have been widely used to examine influenza epidemics and the public health impact of control measures...
June 2, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28542193/an-agent-based-model-of-leukocyte-transendothelial-migration-during-atherogenesis
#7
Rita Bhui, Heather N Hayenga
A vast amount of work has been dedicated to the effects of hemodynamics and cytokines on leukocyte adhesion and trans-endothelial migration (TEM) and subsequent accumulation of leukocyte-derived foam cells in the artery wall. However, a comprehensive mechanobiological model to capture these spatiotemporal events and predict the growth and remodeling of an atherosclerotic artery is still lacking. Here, we present a multiscale model of leukocyte TEM and plaque evolution in the left anterior descending (LAD) coronary artery...
May 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28542182/modelling-the-transmission-and-control-strategies-of-varicella-among-school-children-in-shenzhen-china
#8
Xiujuan Tang, Shi Zhao, Alice P Y Chiu, Hanwu Ma, Xu Xie, Shujiang Mei, Dongfeng Kong, Yanmin Qin, Zhigao Chen, Xin Wang, Daihai He
OBJECTIVES: Varicella (chickenpox) is a highly transmissible childhood disease. Between 2010 and 2015, it displayed two epidemic waves annually among school populations in Shenzhen, China. However, their transmission dynamics remain unclear and there is no school-based vaccination programme in Shenzhen to-date. In this study, we developed a mathematical model to compare a school-based vaccination intervention scenario with a baseline (i.e. no intervention) scenario. METHODS: Data on varicella reported cases were downloaded from the Infectious Disease Reporting Information Management System...
2017: PloS One
https://www.readbyqxmd.com/read/28535815/internet-based-attentional-bias-modification-training-as-add-on-to-regular-treatment-in-alcohol-and-cannabis-dependent-outpatients-a-study-protocol-of-a-randomized-control-trial
#9
Janika Heitmann, Madelon E van Hemel-Ruiter, Karin M Vermeulen, Brian D Ostafin, Colin MacLeod, Reinout W Wiers, Laura DeFuentes-Merillas, Martine Fledderus, Wiebren Markus, Peter J de Jong
BACKGROUND: The automatic tendency to attend to and focus on substance-related cues in the environment (attentional bias), has been found to contribute to the persistence of addiction. Attentional bias modification (ABM) interventions might, therefore, contribute to treatment outcome and the reduction of relapse rates. Based on some promising research findings, we designed a study to test the clinical relevance of ABM as an add-on component of regular intervention for alcohol and cannabis patients...
May 23, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28528206/feasibility-of-atlas-based-active-bone-marrow-sparing-intensity-modulated-radiation-therapy-for-cervical-cancer
#10
Nan Li, Sonal S Noticewala, Casey W Williamson, Hanjie Shen, Igor Sirak, Rafal Tarnawski, Umesh Mahantshetty, Carl K Hoh, Kevin L Moore, Loren K Mell
BACKGROUND: To test the hypothesis that atlas-based active bone marrow (ABM)-sparing intensity modulated radiation therapy (IMRT) yields similar dosimetric results compared to custom ABM-sparing IMRT for cervical cancer patients. METHODS: We sampled 62 cervical cancer patients with pre-treatment FDG-PET/CT in training (n=32) or test (n=30) sets. ABM was defined as the subvolume of the pelvic bone marrow (PBM) with standardized uptake value (SUV) above the mean on the average FDG-PET image (ABMAtlas) vs...
May 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28523054/acute-bacterial-meningitis-in-children-presenting-to-the-children-s-hospital-lahore-before-and-after-pneumococcal-vaccine-in-pakistan-national-immunization-program-a-comparison
#11
Attia Bari, Fatima Zeeshan, Aizza Zafar, Hasan Ejaz, Uzma Jabeen, Ahsan Waheed Rathore
OBJECTIVE: To describe bacteriological profile, morbidity and mortality of acute bacterial meningitis (ABM) in children and to compare these parameters before and after the introduction of Pneumococcal vaccine in Pakistan National Immunization Program. METHODS: The present descriptive study was conducted at the Department of Paediatric Medicine of The Children's Hospital Lahore from January 2012 to December 2015. A total of 503 children one month to five years of age admitted with diagnosis of meningitis were included...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28488805/breastfeeding-considerations-for-mothers-of-infants-with-neonatal-abstinence-syndrome
#12
Amy P Holmes, Holly N Schmidlin, Eliana N Kurzum
Breastfeeding offers many benefits to both mother and baby. Breastfeeding is generally recommended for mothers of infants with neonatal abstinence syndrome (NAS) unless some associated risk outweighs the benefits. Evidence indicates that infants with NAS who receive human milk require less pharmacologic treatment and have shorter hospital lengths of stay. Perhaps the greatest barrier to breastfeeding for women with opioid dependence is the inaccurate and inconsistent information they receive from different sources, including health care professionals...
May 10, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28485006/the-impact-of-appointment-based-medication-synchronization-on-medication-taking-behaviour-and-health-outcomes-a-systematic-review
#13
REVIEW
E Nguyen, D M Sobieraj
WHAT IS KNOWN AND OBJECTIVE: Proactive synchronization of medication refills through an appointment-based model (ABM) is a community pharmacy-based intervention targeting adherence to medications. We aimed to systematically review evidence on the impact of the ABM on medication taking behaviour, health resource utilization, clinical outcomes and the preferences of patients and providers. METHODS: We conducted a systematic literature search of MEDLINE and Scopus from database inception through 6 February 2017...
May 8, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28453890/less-is-more-patient-level-meta-analysis-reveals-paradoxical-dose-response-effects-of-a-computer-based-social-anxiety-intervention-targeting-attentional-bias
#14
REVIEW
Rebecca B Price, Jennie M Kuckertz, Nader Amir, Yair Bar-Haim, Per Carlbring, Meredith L Wallace
BACKGROUND: The past decade of research has seen considerable interest in computer-based approaches designed to directly target cognitive mechanisms of anxiety, such as attention bias modification (ABM). METHODS: By pooling patient-level datasets from randomized controlled trials of ABM that utilized a dot-probe training procedure, we assessed the impact of training "dose" on relevant outcomes among a pooled sample of 693 socially anxious adults. RESULTS: A paradoxical effect of the number of training trials administered was observed for both posttraining social anxiety symptoms and behavioral attentional bias (AB) toward threat (the target mechanism of ABM)...
April 28, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28421127/using-agent-based-models-to-develop-public-policy-about-food-behaviours-future-directions-and-recommendations
#15
REVIEW
Philippe J Giabbanelli, Rik Crutzen
Most adults are overweight or obese in many western countries. Several population-level interventions on the physical, economical, political, or sociocultural environment have thus attempted to achieve a healthier weight. These interventions have involved different weight-related behaviours, such as food behaviours. Agent-based models (ABMs) have the potential to help policymakers evaluate food behaviour interventions from a systems perspective. However, fully realizing this potential involves a complex procedure starting with obtaining and analyzing data to populate the model and eventually identifying more efficient cross-sectoral policies...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28421016/online-coaching-of-emotion-regulation-strategies-for-parents-efficacy-of-the-online-rational-positive-parenting-program-and-attention-bias-modification-procedures
#16
Oana A David, David Capris, Alexandra Jarda
Parenting programs are currently treatment of choice for behavioral disorders in children and one of their main components is reducing the negativity bias in the child-parent dyad. The Rational Positive Parenting Program (rPPP) is a program with a special focus on parent emotion-regulation functional reappraisal strategies, which has recently received consistent support for reducing child externalizing and internalizing disorders. In the last years, online interventions were proliferated and the Attention Bias Modification (ABM) becoming a promising implicit therapeutic intervention based on attention deployment emotion-regulation strategy, or adjunctive module to usual treatments, with results in multiple domains, varying from pain to self-esteem and emotional disorders (e...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28384572/assessing-surface-water-flood-risk-and-management-strategies-under-future-climate-change-insights-from-an-agent-based-model
#17
K Jenkins, S Surminski, J Hall, F Crick
Climate change and increasing urbanization are projected to result in an increase in surface water flooding and consequential damages in the future. In this paper, we present insights from a novel Agent Based Model (ABM), applied to a London case study of surface water flood risk, designed to assess the interplay between different adaptation options; how risk reduction could be achieved by homeowners and government; and the role of flood insurance and the new flood insurance pool, Flood Re, in the context of climate change...
October 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28365845/assessing-the-effects-of-rural-livelihood-transition-on-non-point-source-pollution-a-coupled-abm-iecm-model
#18
Chengcheng Yuan, Liming Liu, Jinwei Ye, Guoping Ren, Dong Zhuo, Xiaoxing Qi
Water pollution caused by anthropogenic activities and driven by changes in rural livelihood strategies in an agricultural system has received increasing attention in recent decades. To simulate the effects of rural household livelihood transition on non-point source (NPS) pollution, a model combining an agent-based model (ABM) and an improved export coefficient model (IECM) was developed. The ABM was adopted to simulate the dynamic process of household livelihood transition, and the IECM was employed to estimate the effects of household livelihood transition on NPS pollution...
May 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28355160/probing-protein-lipid-interactions-by-fret-between-membrane-fluorophores
#19
Valeriya M Trusova, Galyna P Gorbenko, Todor Deligeorgiev, Nikolai Gadjev
Förster resonance energy transfer (FRET) is a powerful fluorescence technique that has found numerous applications in medicine and biology. One area where FRET proved to be especially informative involves the intermolecular interactions in biological membranes. The present study was focused on developing and verifying a Monte-Carlo approach to analyzing the results of FRET between the membrane-bound fluorophores. This approach was employed to quantify FRET from benzanthrone dye ABM to squaraine dye SQ-1 in the model protein-lipid system containing a polycationic globular protein lysozyme and negatively charged lipid vesicles composed of phosphatidylcholine and phosphatidylglycerol...
September 21, 2016: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28350312/miller-s-pyramid-and-core-competency-assessment-a-study-in-relationship-construct-validity
#20
Betsy White Williams, Phil D Byrne, Dillon Welindt, Michael V Williams
INTRODUCTION: Continuous professional development relies on the link between performance and an educational process aimed at improving knowledge and skill. One of the most broadly used frameworks for assessing skills is Miller's Pyramid. This Pyramid has a series of levels of achievement beginning with knowledge (at the base) and ending with routine application in the clinical setting. METHODS: The purpose of this study was to determine the degree of convergence of two measurement methods, one based on Miller's framework, the second using the Accreditation Council for Graduate Medical Education/American Board of Medical Specialties (ACGME/ABMS) Core Competency framework...
October 2016: Journal of Continuing Education in the Health Professions
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