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https://www.readbyqxmd.com/read/28818559/-to-boldly-go-where-no-one-has-gone-before
#1
Keith W Kelley
Americans are suffering from a culture of taking pills. Six out of ten Americans utilize at least one prescription drug, and more than one in ten use five or more prescription medicines. Although this torrent of taking pills is already high, drug use in the USA has not yet crested. Prescription drugs have specific targets, but often they adversely affect other tissues and organs. In keeping with the mission of the recently named National Center for Complementary and Integrative Health (NCCIH), Brain, Behavior, and Immunity searches for the underlying cause and potential efficacy of both drug and non-drug interventions...
August 14, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28817703/quality-of-life-of-inguinal-hernia-patients-in-taiwan-the-application-of-the-hernia-specific-quality-of-life-assessment-instrument
#2
Chi-Cheng Huang, Feng-Chuan Tai, Tzung-Hsin Chou, Heng-Hui Lien, Jaan-Yeh Jeng, Thien-Fiew Ho, Ching-Shui Huang
BACKGROUND: With the development of prosthetic mesh and tension free techniques, the recurrence rate following inguinal hernia repair has been reduced, and hernia outcomes research should focus on post-operative quality of life and potential complications. STUDY DESIGN: A novel hernia quality of life assessment instrument, HERQL, was developed. The HERQL questionnaire comprises a 4-item summative pain score measuring pain and discomfort resulting from various strenuous activities...
2017: PloS One
https://www.readbyqxmd.com/read/28811955/the-effects-of-group-based-versus-individual-based-tai-chi-training-on-nonmotor-symptoms-in-patients-with-mild-to-moderate-parkinson-s-disease-a-randomized-controlled-pilot-trial
#3
Jing Hui Yang, Ya Qun Wang, Sai Qing Ye, You Gen Cheng, Yu Chen, Xiao Zhen Feng
OBJECTIVE: To compare the effects of group-based and individual-based Tai Chi training on nonmotor symptoms in patients with mild to moderate Parkinson's disease. DESIGN: Randomized controlled pilot study. METHODS: 36 community-dwelling patients with Parkinson's disease (PD) were randomly assigned to either group-based training group (n = 19) or individual-based group (n = 17). Both groups received same content of Tai Chi training 3 times a week for 13 weeks...
2017: Parkinson's Disease
https://www.readbyqxmd.com/read/28810821/idiopathic-low-ovarian-reserve-is-associated-with-more-frequent-positive-thyroid-peroxidase-antibody
#4
Chien-Wen Chen, Ya-Li Huang, Rui Lan Huang, Chii-Ruey Tzeng, Chi-Huang Chen
BACKGROUND: While screening on thyroid peroxidase antibody (TPO-Ab) has been recommended in women with primary ovarian insufficiency, the relationship between thyroid autoimmunity (TAI) and ovarian reserve remains undetermined. Because the TAI prevalence was reported to be different between races, we aimed to investigate the TAI prevalence in Chinese women with different ovarian reserve. METHODS: This is a cross-sectional study conducted in a university infertility clinic between October 2013 and March 2016...
August 16, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28802468/integrative-medicine-for-insomnia
#5
REVIEW
Eric S Zhou, Paula Gardiner, Suzanne M Bertisch
Difficulty initiating and/or maintaining sleep is a common issue. Patients experiencing insomnia symptoms frequently self-treat their symptoms with sleep medications. However, there remains concern regarding the short- and long-term health impacts of sleep medications. This article discusses the evidence supporting integrative approaches to insomnia treatment, including cognitive-behavioral therapy and mind-body therapies (mindfulness meditation, yoga, tai chi), as well as emerging data for use of other less well supported approaches (dietary supplements, acupuncture)...
September 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/28796502/sky-blue-emitting-iridium-iii-complexes-bearing-nonplanar-tetradentate-chromophore-and-bidentate-ancillary
#6
Yu-Sian Li, Jia-Ling Liao, Ke-Ting Lin, Wen-Yi Hung, Shih-Hung Liu, Gene-Hsiang Lee, Pi-Tai Chou, Yun Chi
Tetradentate chelates bearing tripodal arranged terpyridine and a functional pyrazole unit (i.e., L1-H and L2-H) were employed in preparation of Ir(III) complexes [Ir(L1)Cl2] (1) and [Ir(L2)Cl2] (2); subsequent chloride-to-bipyrazolate substitution gave [Ir(L1)(bipz)] (3) and [Ir(L2)(bipz)] (4). Single-crystal X-ray structural studies on 1 and 3 showed the possession of a tetradentate chelate, whereas the remaining cis-sites are occupied by either dual chlorides or the bipz chelate, respectively. Sky blue organic light-emitting diode with peak efficiencies (10...
August 10, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28793312/delays-in-hiv-diagnosis-and-associated-factors-among-patients-presenting-with-advanced-disease-at-a-tertiary-care-hospital-in-beijing-china
#7
Jing Xie, Evelyn Hsieh, Meng-Qing Sun, Huan-Ling Wang, Wei Lv, Hong-Wei Fan, Tai-Sheng Li
Delayed diagnosis of HIV infection is associated with advanced immunosuppression and increased risk of onward transmission. Little data exists regarding factors associated with diagnostic delays among patients presenting with advanced HIV disease in China. Medical records of patients with HIV/AIDS hospitalized at a 2000-bed tertiary hospital in Beijing, China between 1997 and 2012 were retrospectively reviewed. Demographic and clinical data of patients newly diagnosed with HIV at the hospital were abstracted...
2017: PloS One
https://www.readbyqxmd.com/read/28783470/differences-in-fitness-level-between-women-aged-60-and-over-participating-in-three-different-supervised-exercise-programs-and-a-sedentary-group
#8
Maria Viladrosa, Ana Lavedán, Pilar Jürschik, Sebastià Mas-Alòs, Antoni Planas-Anzano, Olga Masot
The aim of this study was to compare fitness levels in women aged 60 and over participating in a supervised exercise program (involving tai chi, recreational gymnastics, and/or aquatic fitness) with those in a sedentary group. An observational, descriptive, cross-sectional study was performed on a total of 171 women aged from 60 to 92 who attended public community clubs for older adults. The instruments used included the Senior Fitness Test, the Tinetti Balance Assessment Tool, the Katz Index, and the Lawton & Brody Activities of Daily Living Scale...
August 7, 2017: Journal of Women & Aging
https://www.readbyqxmd.com/read/28772594/in-vitro-evaluation-of-dentin-tubule-occlusion-for-novel-calcium-lactate-phosphate-clp-paste
#9
Jen-Chang Yang, Hsin-Tai Hu, Sheng-Yang Lee, Sung-Chih Hsieh, Pei-Chi Huang, Chen-Feng Ma, Dian-Yu Ji, Liang-Yu Chang, Nai-Chia Teng
INTRODUCTION: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. METHODS: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate(®) Pro-Relief™ paste, CLP paste, and double distilled water (ddH₂O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment...
February 27, 2017: Materials
https://www.readbyqxmd.com/read/28766686/benzyl-isothiocyanate-and-phenethyl-isothiocyanate-inhibit-murine-melanoma-b16f10-cell-migration-and-invasion-in-vitro
#10
Kuang-Chi Lai, Yung-Ting Hsiao, Jiun-Long Yang, Yi-Shih Ma, Yi-Ping Huang, Tai-An Chiang, Jing-Gung Chung
Benzyl isothiocyanate (BITC), and phenethyl isothiocyanate (PEITC) have been demonstrated to induce anticancer function in many human cancer cells and also inhibit cancer cell migration and invasion. However, there are no studies that show BITC and PEITC to inhibit cell migration and invasion in mouse melanoma B16F10 cells. In this study, we investigated anti-metastasis effects of BITC and PEITC in melanoma cancer cells in vitro. Under sub-lethal concentrations (from 1, 2.5 up to 5 µM), BITC and PEITC significantly inhibited cell mobility, migration and invasion nature of B16F10 cells...
September 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28764539/magnetic-induction-of-hyperthermia-by-a-modified-self-learning-fuzzy-temperature-controller
#11
Wei-Cheng Wang, Cheng-Chi Tai
The aim of this study involved developing a temperature controller for magnetic induction hyperthermia (MIH). A closed-loop controller was applied to track a reference model to guarantee a desired temperature response. The MIH system generated an alternating magnetic field to heat a high magnetic permeability material. This wireless induction heating had few side effects when it was extensively applied to cancer treatment. The effects of hyperthermia strongly depend on the precise control of temperature. However, during the treatment process, the control performance is degraded due to severe perturbations and parameter variations...
July 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28753677/pyruvate-kinase-m2-is-a-poor-prognostic-marker-of-and-a-therapeutic-target-in-ovarian-cancer
#12
Tai-Kuang Chao, Tien-Shuo Huang, Yu-Ping Liao, Rui-Lan Huang, Po-Hsuan Su, Hueng-Yuan Shen, Hung-Cheng Lai, Yu-Chi Wang
Pyruvate kinase M2 (PKM2) regulates glycolysis and oxidative phosphorylation; however, the role of PKM2 in ovarian cancer remains largely unknown. We investigated whether ovarian cancer metabolism could provide insight into the development of therapeutic strategies. We performed immunohistochemical staining for PKM2 on a tissue microarray for multivariate analysis. It revealed that patients exhibiting higher PKM2 expression were significantly associated with malignancy groups (p < 0.001) and pathogenesis models (p < 0...
2017: PloS One
https://www.readbyqxmd.com/read/28752509/the-association-of-apolipoprotein-e-allele-4-polymorphism-with-the-recovery-of-sleep-disturbance-after-mild-traumatic-brain-injury
#13
Hsun-Hua Lee, Chun-Ting Yeh, Ju-Chi Ou, Hon-Ping Ma, Kai-Yun Chen, Cheng-Fu Chang, Jing-Huei Lai, Kuo-Hsing Liao, Chien-Min Lin, Shu-Yu Lin, Dean Wu, Yao-Hsien Huang, Chaur-Jong Hu, Chien-Tai Hong
PURPOSE: Mild traumatic brain injury (mTBI) is a major public health concern. The apolipoprotein E (APOE) gene contains three polymorphisms, and the APOE4 polymorphism may affect several physiological states, such as the recovery from mTBI as well as sleep. This study aims to investigate the association between APOE4 with the recovery of sleep disturbance after mTBI. METHODS: From May 2012 to Aug 2015, 189 mTBI patients completed baseline (1st week post-mTBI) and follow-up (6th week post-mTBI) sleep assessments that involved using the Pittsburgh Sleep Quality Index (PSQI)...
March 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/28751273/overexpression-and-characterization-of-a-recombinant-l-ribose-isomerase-from-actinotalea-fermentans-atcc-43279
#14
Wen-Chi Tseng, Tai-Jeng Wu, Ya-Ju Chang, Hung-Wen Cheng, Tsuei-Yun Fang
A putative l-ribose isomerase (EC 5.3.1.B3, l-RI) gene of Actinotalea fermentans ATCC 43279 was chemically synthesized, subcloned into pET-21b vector, and then overexpressed in Escherichia coli. After 0.5mM IPTG induction at 20°C for 20h, the recombinant l-RI was highly expressed with up to 50% of the total proteins. About 70% of the expressed l-RI appeared in the cell-free extract as a soluble form, and a high yield of active l-RI, 23,800U/L or 952U/g of wet cells, was achieved. The purified recombinant l-RI demonstrated its optimal activity at 45°C and pH 8 (in tricine-NaOH buffer)...
July 24, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28751088/hypoalbuminemia-is-a-predictor-of-mortality-and-rebleeding-in-peptic-ulcer-bleeding-under-proton-pump-inhibitor-use
#15
Hsiu-Chi Cheng, Er-Hsiang Yang, Chung-Tai Wu, Wen-Lun Wang, Po-Jun Chen, Meng-Ying Lin, Bor-Shyang Sheu
BACKGROUND/PURPOSE: Peptic ulcer bleeding remains a deadly disease, and a simple indicator of long-term outcomes is crucial. This study validated whether hypoalbuminemia and its related factors in patients with peptic ulcer bleeding can indicate long-term mortality and rebleeding under proton pump inhibitor use. METHODS: The prospective cohort study enrolled 426 patients with peptic ulcer bleeding who had high risk stigmata at endoscopy and had received endoscopic hemostasis...
July 24, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28750970/the-effect-of-tai-chi-exercises-on-postural-stability-and-control-in-older-patients-with-knee-osteoarthritis
#16
Elham Ghandali, Saeed Talebian Moghadam, Mohammad Reza Hadian, Gholamreza Olyaei, Shohreh Jalaie, Elaheh Sajjadi
A few studies have examined the effect of Tai Chi on balance in elder patients with knee osteoarthritis (OA). The aim of this study was to determine the balance measures in elder patients with knee OA after Tai Chi exercises. For this purpose 14 females and 6 males with knee OA were chosen. Area and mean velocity of the center of pressure movements (CoP) were measured by force plate in standing positions (on foam and rigid surfaces). The measurements of area and mean velocity of CoP were performed before and after 60 min of Tai Chi sessions (twice a week for 8 weeks)...
July 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28749970/effectiveness-of-physical-activity-on-patients-with-depression-and-parkinson-s-disease-a-systematic-review
#17
Pei-Ling Wu, Megan Lee, Tzu-Ting Huang
AIM: In this paper we aimed to systematically review the literature on physical activity's effect on depressive symptoms in Parkinson disease. BACKGROUND: Depression is a common symptom of Parkinson's disease and is associated with increased disability, rapid progression of motor symptoms, mortality, and adverse effects on Quality of Life. DESIGN: A systematic review of primary research was undertaken and conducted according to the Preferred Reporting Items for Systematic Reviews...
2017: PloS One
https://www.readbyqxmd.com/read/28742289/tai-chi-exercise-for-the-quality-of-life-in-a-perimenopausal-women-organization-a-systematic-review
#18
Ying Wang, Weichao Shan, Qing Li, Na Yang, Weiying Shan
BACKGROUND: Improvement of the quality of life in perimenopausal women has recently become an important global health issue. Extensive research reports provide evidence of Tai Chi for the quality of life, but no systematic review has individually investigated Tai Chi as a main intervention on the quality of life in perimenopausal women. OBJECTIVE: To assess clinical evidence of Tai Chi for the quality of life in perimenopausal women. METHODS: Studies related to the effect of Tai Chi on the quality of life in perimenopausal women in the databases of China and abroad were searched...
August 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28736853/tai-chi-for-risk-of-falls-a-meta-analysis
#19
Rafael Lomas-Vega, Esteban Obrero-Gaitán, Francisco J Molina-Ortega, Rafael Del-Pino-Casado
OBJECTIVES: To analyze the effectiveness of tai chi for falls prevention. DESIGN: Systematic review and meta-analysis. SETTING: Pubmed, Scopus, CINHAL, and Physiotherapy Evidence Database (PEDro) were searched to May 26, 2016. PARTICIPANTS: Older adult population and at-risk adults. INTERVENTION: Randomized controlled trials analyzing the effect of tai chi versus other treatments on risk of falls...
July 24, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28736535/mind-body-practice-changes-fractional-amplitude-of-low-frequency-fluctuations-in-intrinsic-control-networks
#20
Gao-Xia Wei, Zhu-Qing Gong, Zhi Yang, Xi-Nian Zuo
Cognitive control impairment is a typical symptom largely reported in populations with neurological disorders. Previous studies have provided evidence about the changes in cognitive control induced by mind-body training. However, the neural correlates underlying the effect of extensive mind-body practice on cognitive control remain largely unknown. Using resting-state functional magnetic resonance imaging, we characterized dynamic fluctuations in large-scale intrinsic connectivity networks associated with mind-body practice, and examined their differences between healthy controls and Tai Chi Chuan (TCC) practitioners...
2017: Frontiers in Psychology
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