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Diabetes dementia cancer preventive medicine

David L Katz, Elizabeth P Frates, Jonathan P Bonnet, Sanjay K Gupta, Erkki Vartiainen, Richard H Carmona
The power of lifestyle as medicine was perceived thousands of years ago. There is now consistent and compelling science to support the important influence of lifestyle on health. Approximately 80% of chronic disease and premature death could be prevented by not smoking, being physically active, and adhering to a healthful dietary pattern. Cardiovascular disease, diabetes, stroke, dementia, and cancer are all influenced by lifestyle choices. Despite the ample evidence about what behaviors promote health, confusion still prevails among the general population...
January 1, 2017: American Journal of Health Promotion: AJHP
S W Seto, G Y Yang, H Kiat, A Bensoussan, Y W Kwan, D Chang
Diabetes mellitus (DM) is a metabolic disorder affecting a large number of people worldwide. Numerous studies have demonstrated that DM can cause damage to multiple systems, leading to complications such as heart disease, cancer, and cerebrovascular disorders. Numerous epidemiological studies have shown that DM is closely associated with dementia and cognition dysfunction, with recent research focusing on the role of DM-mediated cerebrovascular damage in dementia. Despite the therapeutic benefits of antidiabetic agents for the treatment of DM-mediated cognitive dysfunction, most of these pharmaceutical agents are associated with various undesirable side-effects and their long-term benefits are therefore in doubt...
2015: International Journal of Endocrinology
Hideo Takayanagi
With the rate of aging rising each year, the number of patients with dementia increases. The latest study released by the Ministry of Health, Labour and Welfare estimated that, as of 2012, there were a total of 3.05 million people with dementia in Japan, with 10% of aged 65 and over, 15% of aged 70 and over, 20% of aged 75 and over, and 40% of aged 85 and over. Dementia includes Alzheimer's disease, which makes up the most cases, dementia with Lewy bodies, frontotemporal dementia, and cerebrovascular dementia which is caused by a cerebral infarction or cerebral hemorrhage...
December 2014: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Mohsen Hamidpour, Rafie Hamidpour, Soheila Hamidpour, Mina Shahlari
For a long time, sage (Salvia) species have been used in traditional medicine for the relief of pain, protecting the body against oxidative stress, free radical damages, angiogenesis, inflammation, bacterial and virus infection, etc., Several studies suggest that sage species can be considered for drug development because of their reported pharmacology and therapeutic activities in many countries of Asia and Middle East, especially China and India. These studies suggest that Salvia species, in addition to treating minor common illnesses, might potentially provide novel natural treatments for the relief or cure of many serious and life-threatening diseases such as depression, dementia, obesity, diabetes, lupus, heart disease, and cancer...
April 2014: Journal of Traditional and Complementary Medicine
Patrizia Russo, Massimo Fini, Alfredo Cesario
No abstract text is available yet for this article.
2014: Current Pharmaceutical Design
Barbara J Boucher
This report reviews evidence on disorders related to inadequate vitamin D repletion in older people. Vitamin D is as essential for bone health in adults as in children, preventing osteomalacia and muscle weakness and protecting against falls and low-impact fractures. Vitamin D is provided by skin synthesis by UVB-irradiation from summer sunshine and to a small extent by absorption from food. However, these processes become less efficient with age. Loss of mobility or residential care restricts solar exposure...
August 2012: Aging and Disease
Heiner Boeing, Angela Bechthold, Achim Bub, Sabine Ellinger, Dirk Haller, Anja Kroke, Eva Leschik-Bonnet, Manfred J Müller, Helmut Oberritter, Matthias Schulze, Peter Stehle, Bernhard Watzl
BACKGROUND: Vegetables and fruit provide a significant part of human nutrition, as they are important sources of nutrients, dietary fibre, and phytochemicals. However, it is uncertain whether the risk of certain chronic diseases can be reduced by increased consumption of vegetables or fruit by the general public, and what strength of evidence has to be allocated to such an association. METHODS: Therefore, a comprehensive analysis of the studies available in the literature and the respective study results has been performed and evaluated regarding obesity, type 2 diabetes mellitus, hypertension, coronary heart disease (CHD), stroke, cancer, chronic inflammatory bowel disease (IBD), rheumatoid arthritis (RA), chronic obstructive pulmonary disease (COPD), asthma, osteoporosis, eye diseases, and dementia...
September 2012: European Journal of Nutrition
B Ray, N B Chauhan, D K Lahiri
Alzheimer's disease (AD) is the most common form of dementia in the older people and 7(th) leading cause of death in the United States. Deposition of amyloid-beta (Aβ) plaques, hyperphosphorylation of microtubule associated protein tau (MAPT), neuroinflammation and cholinergic neuron loss are the major hallmarks of AD. Deposition of Aβ peptides, which takes place years before the clinical onset of the disease can trigger hyperphophorylation of tau proteins and neuroinflammation, and the latter is thought to be primarily involved in neuronal and synaptic damage seen in AD...
2011: Current Medicinal Chemistry
Olga Golubnitschaja
Predictive medicine is a new philosophy in healthcare and an attractive subject for currently initiated research activities aimed at a potential application of innovative biotechnologies in the prediction of human pathologies, a development of well-timed prevention and individual therapy-planning. Diabetes care is one of the best examples of an absolute necessity for well-timed prediction, prevention and personalized treatment. Diabetes mellitus frequently results in diverse severe complications, such as retinopathy, nephropathy, silent ischemia, dementia, and cancer--the cascade of chronic complications appearing as "domino-effect"...
June 2008: Infectious Disorders Drug Targets
H Sandholzer, W Hellenbrand, W Renteln-Kruse, C Van Weel, P Walker
BACKGROUND: There is a need for a standard preventive assessment scheme, which is effective, feasible and acceptable throughout European primary care. METHODS: A consensus based guideline including systematic reviews of the evidence was done by an expert panel of general practitioners (core group) and epidemiologists / geriatricians from seven European countries. RESULTS: The Step group identified 8 health domains to be considered in a preventive assessment; client's perspective and attitudes...
December 10, 2004: Deutsche Medizinische Wochenschrift
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