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https://www.readbyqxmd.com/read/28239827/quantitative-difference-of-acute-intraoperative-expansion-in-various-body-regions
#1
E Raposio, N Bertozzi
OBJECTIVE: To investigate the efficacy of intraoperative sustained limited expansion (ISLE) by examining the ex vivo biomechanical properties of acutely expanded skin flaps. MATERIALS AND METHODS: Fourteen fresh male cadavers were tested. On both sides of each cadaver, a 4 × 10 cm, the laterally based flap was raised at the external auditory canal of the scalp and a 15 × 8 cm, the proximately based flap was raised at the lateral arm, anterior thorax, and lateral thigh...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239604/predictors-of-antenatal-care-skilled-birth-attendance-and-postnatal-care-utilization-among-the-remote-and-poorest-rural-communities-of-zambia-a-multilevel-analysis
#2
Choolwe Jacobs, Mosa Moshabela, Sitali Maswenyeho, Nildah Lambo, Charles Michelo
OBJECTIVE: Optimal utilization of maternal health-care services is associated with reduction of mortality and morbidity for both mothers and their neonates. However, deficiencies and disparity in the use of key maternal health services within most developing countries still persist. We examined patterns and predictors associated with the utilization of specific indicators for maternal health services among mothers living in the poorest and remote district populations of Zambia. METHODS: A cross-sectional baseline household survey was conducted in May 2012...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28239593/ectopic-esthesioneuroblastoma-of-the-sphenoclivus-a-rare-entity
#3
Farah Dayana Zahedi, Balwant Singh Gendeh, Salina Husain, Ramesh Kumar, Thean Yean Kew
Esthesioneuroblastoma is a rare malignant neoplasm of oflactory neuroepithelium and usually located at the olfactory cleft at superior nasal cavity. Ectopic localization of esthesioneuroblastoma is even rarer and usually posed with a diagnostic dilemma and delay in the diagnosis and management, We report a rare case of ectopic esthesioneuroblastoma of the sphenoclivus with the presentation of intermittent unilateral epistaxis, intermittent intractable headache without anosmia. Nasal endoscopy findings showed a pulsatile mass at the anterior face of the sphenoid sinus with extension posteriorly towards the clivus region and occupying the floor of the sphenoid sinus...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239323/metronidazole-induced-encephalopathy-in-a-patient-with-crohn-s-disease
#4
Jihye Kim, Jaeyoung Chun, Jae Yong Park, Seung Wook Hong, Joo Young Lee, Jin Woo Kang, Seongjun Hwang, Sang-Bae Ko, Jong Pil Im, Joo Sung Kim
Metronidazole is a widely used antibiotic for the treatment of anaerobic bacterial infections. Metronidazole-induced encephalopathy (MIEP) is a rare but potentially reversible disease. The mechanism of MIEP remains unclear, and differences in the neurotoxic effects of oral versus intravenous (IV) metronidazole administration have not yet been determined. We report the case of a Crohn's disease (CD) patient who experienced encephalopathy immediately after a single IV dose of metronidazole following long-term exposure to the oral form of the drug...
January 2017: Intestinal Research
https://www.readbyqxmd.com/read/28239052/an-atypical-case-of-recurrent-carotid-body-carcinoma-in-a-young-adult-dog-histopathological-immunohistochemical-and-electron-microscopic-study
#5
Angeline Ping Ping Teh, Watanyoo Pratakpiriya, Yuichi Hidaka, Hiroyuki Sato, Takuya Hirai, Ryoji Yamaguchi
A 3.5-year-old female Chihuahua was presented with complaint of neck pain, intermittent cough and dysphagia. Physical examination and diagnostic imaging of neck region revealed a solid and highly vascularized mass involving the retropharyngeal region. Histologically, the mass showed an atypical zellballen pattern which comprised of high density of type I chief cells with high nuclear cytoplasmic ratio and separated by delicate fibrovascular stroma. Immunoreactivity for neuroendocrine markers was diffusely positive in cytoplasm of tumor cells...
February 27, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28238671/cardiac-autonomic-ganglia-ablation-suppresses-atrial-fibrillation-in-a-canine-model-of-acute-intermittent-hypoxia
#6
Xiaomei Yu, Zhibing Lu, Wenbo He, Bo He, Ruisong Ma, Jing Xie, Hong Jiang
BACKGROUND: Atrial fibrillation (AF) is associated with hypoxia in which cardiac autonomic nerve system (ANS) plays an important role. Our previous studies indicated that ANS is activated in an intermittent hypoxia model and contributes to AF initiation. This study aimed to investigate the effects of cardiac ganglionated plexus (GP) ablation on AF in this model. METHODS AND RESULTS: In thirteen anesthetized male dogs, GP ablation was applied after 1h of intermittent hypoxia in the first group (n=7) and before that in the second group (n=6)...
February 23, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28238588/rest-stress-limb-perfusion-imaging-in-humans-with-contrast-ultrasound-using-intermediate-power-imaging-and-microbubbles-resistant-to-inertial-cavitation
#7
Brian P Davidson, James Hodovan, J Todd Belcik, Federico Moccetti, Aris Xie, Azzdine Y Ammi, Jonathan R Lindner
BACKGROUND: Contrast-enhanced ultrasound (CEU) limb perfusion imaging is a promising approach for evaluating peripheral artery disease (PAD). However, low signal enhancement in skeletal muscle has necessitated high-power intermittent imaging algorithms, which are not clinically feasible. We hypothesized that CEU using a combination of intermediate power and a contrast agent resistant to inertial cavitation would allow real-time limb stress perfusion imaging. METHODS: In normal volunteers, CEU of the calf skeletal muscle was performed on separate days with Sonazoid, Optison, or Definity...
February 23, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28238546/regulation-of-thalamic-and-cortical-network-synchrony-by-scn8a
#8
Christopher D Makinson, Brian S Tanaka, Jordan M Sorokin, Jennifer C Wong, Catherine A Christian, Alan L Goldin, Andrew Escayg, John R Huguenard
Voltage-gated sodium channel (VGSC) mutations cause severe epilepsies marked by intermittent, pathological hypersynchronous brain states. Here we present two mechanisms that help to explain how mutations in one VGSC gene, Scn8a, contribute to two distinct seizure phenotypes: (1) hypoexcitation of cortical circuits leading to convulsive seizure resistance, and (2) hyperexcitation of thalamocortical circuits leading to non-convulsive absence epilepsy. We found that loss of Scn8a leads to altered RT cell intrinsic excitability and a failure in recurrent RT synaptic inhibition...
February 18, 2017: Neuron
https://www.readbyqxmd.com/read/28238545/drawing-a-line-in-the-sand-effectiveness-of-off-highway-vehicle-management-in-california-s-sonoran-desert
#9
Nathan A Custer, Lesley A DeFalco, Kenneth E Nussear, Todd C Esque
Public land policies manage multiple uses while striving to protect vulnerable plant and wildlife habitats from degradation; yet the effectiveness of such policies are infrequently evaluated, particularly for remote landscapes that are difficult to monitor. We assessed the use and impacts of recreational vehicles on Mojave Desert washes (intermittent streams) in the Chemehuevi Desert Wildlife Management Area (DWMA) of southern California. Wash zones designated as open and closed to off-highway vehicle (OHV) activity were designed in part to protect Mojave desert tortoise (Gopherus agassizii) habitat while allowing recreation in designated areas...
February 23, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28238209/a-two-phase-model-for-chronic-disease-processes-under-intermittent-inspection
#10
Ying Wu, Richard J Cook
A model is developed for chronic diseases with an indolent phase that is followed by a phase with more active disease resulting in progression and damage. The time scales for the intensity functions for the active phase are more naturally based on the time since the start of the active phase, corresponding to a semi-Markov formulation. This two-phase model enables one to fit a separate regression model for the duration of the indolent phase and intensity-based models for the more active second phase. In cohort studies for which the disease status is only known at a series of clinical assessment times, transition times are interval-censored, which means the time origin for phase II is interval-censored...
February 26, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28238122/amelioration-of-drought-induced-negative-responses-by-elevated-co2-in-field-grown-short-rotation-coppice-mulberry-morus-spp-a-potential-bio-energy-tree-crop
#11
Kalva Madhana Sekhar, Kanubothula Sitarami Reddy, Attipalli Ramachandra Reddy
Present study describes the responses of short rotation coppice (SRC) mulberry, a potential bio-energy tree, grown under interactive environment of elevated CO2 (E) and water stress (WS). Growth in E stimulated photosynthetic performance in well-watered (WW) as well as during WS with significant increases in light-saturated photosynthetic rates (A Sat), water use efficiency (WUEi), intercellular [CO2], and photosystem-II efficiency (F V/F M and ∆F/F M') with concomitant reduction in stomatal conductance (g s) and transpiration (E) compared to ambient CO2 (A) grown plants...
February 25, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28237986/relationship-among-mortality-of-patients-with-acute-kidney-injury-after-cardiac-surgery-fluid-balance-and-ultrafiltration-of-renal-replacement-therapy-an-observational-study
#12
Buyun Wu, Jian Sun, Si Liu, Xiangbao Yu, Yamei Zhu, Huijuan Mao, Changying Xing
BACKGROUND/AIMS: The study aimed to investigate the relationship among mortality of patients with cardiac surgery-associated acute kidney injury (CSA-AKI), fluid balance, and ultrafiltration of renal replacement therapy (RRT). METHODS: From January 2009 to October 2015, hospitalized patients with CSA-AKI receiving continuous or prolonged intermittent RRT were screened. The effects of fluid balance and ultrafiltration of RRT on clinical outcome were analyzed. RESULTS: The 30-day mortality of all the 63 patients in the study was 58...
February 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28237831/different-origin-and-dispersal-of-sulphadoxine-resistant-plasmodium-falciparum-haplotypes-between-eastern-africa-and-democratic-republic-of-congo
#13
Vito Baraka, Christopher Delgado-Ratto, Sidsel Nag, Deus S Ishengoma, Rashid A Madebe, Hypolite Muhindo Mavoko, Carolyn Nabasumba, Pascal Lutumba, Michael Alifrangis, Jean-Pierre Van Geertruyden
Sulphadoxine/pyrimethamine (SP) is still used for malaria control in sub-Saharan Africa; however, widespread resistance is a major concern. This study aimed to determine the dispersal and origin of sulphadoxine resistance lineages in the Democratic Republic of the Congo compared with East African Plasmodium falciparum dihydropteroate synthetase (Pfdhps) haplotypes. The analysis involved 264 isolates collected from patients with uncomplicated malaria from Tanzania, Uganda and DR Congo. Isolates were genotyped for Pfdhps mutations at codons 436, 437, 540, 581 and 613...
February 22, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28236850/intermittent-hypoxia-as-a-means-to-improve-aerobic-capacity-in-type-2-diabetes
#14
R J Leone, S Lalande
Physical inactivity and a low maximal aerobic capacity (VO2max) strongly predict morbidity and mortality in patients with type 2 diabetes (T2D). Patients with T2D have a reduced VO2max when compared with healthy individuals of similar age, weight, and physical activity levels, and this lower aerobic capacity is usually attributed to a reduced oxygen delivery to the working muscles. The oxygen carrying capacity of the blood, as well as increases in cardiac output and blood flow, contribute to the delivery of oxygen to the active muscles during exercise...
March 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28236825/nitrogen-removal-in-a-staged-anaerobic-aerobic-sludge-digestion-system
#15
Jongmin Kim, John T Novak
  A mixture of primary and secondary municipal sludge was treated in the digestion system consisting of a first-stage mesophilic anaerobic and a second-stage aerobic digester. The study was to monitor solids and nitrogen removal efficiencies under different operational conditions in the aerobic digester.In the first phase, the aerobic digester was batch fed under continuous aeration. More solids and ammonia were removed as the aerobic retention time increased. About 90% or greater ammonia was removed at 3 days or longer aerobic retention times...
January 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28236734/midwives-provision-of-antimalaria-services-to-pregnant-women-in-uganda
#16
Richard Serunkuma Bbosa, Valerie Janet Ehlers
OBJECTIVES: malaria causes complications during 80% of all pregnancies in Uganda. However, only 48% of Ugandan pregnant women took one dose of intermittent preventive therapy while merely 27% took the second dose during 2011. This study investigated midwives' provision of anti-malaria services in the Buikwe District of Uganda. DESIGN: a quantitative exploratory descriptive design was used. SETTING: prenatal clinics (n=16) in the Buikwe District of Uganda RESPONDENTS: questionnaires were completed by 40 (out of a population of 45) midwives...
February 20, 2017: Midwifery
https://www.readbyqxmd.com/read/28236270/oxidative-and-carbonyl-stress-in-pregnant-women-with-obstructive-sleep-apnea
#17
Nazia Khan, Geralyn Lambert-Messerlian, Joao Filipe Monteiro, Julius Hodosy, Ľubomíra Tóthová, Peter Celec, Elizabeth Eklund, Patrizia Curran, Ghada Bourjeily
PURPOSE: Pregnant women are particularly susceptible to sleep-disordered breathing. Obstructive sleep apnea (OSA) in pregnancy is associated with poor pregnancy and fetal outcomes. Oxidative stress caused by intermittent hypoxemia and reoxygenation may impact pregnancy health. We hypothesize that pregnant women with OSA have a pronounced oxidative stress profile. METHODS: A case-control study was performed to study oxidative stress markers in the serum of pregnant women with or without OSA...
February 24, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28235547/intermittent-hypercapnic-hypoxia-effects-on-the-nicotinic-acetylcholine-receptors-in-the-developing-piglet-hippocampus-and-brainstem
#18
Arunnjah Vivekanandarajah, Atqiya Aishah, Karen A Waters, Rita Machaalani
This study investigated the effects of acute (1day) vs repeated (4days) exposure to intermittent hypercapnic hypoxia (IHH) on the immunohistochemical expression of α2, α3, α5, α7, α9 and β2 nicotinic acetylcholine receptor (nAChR) subunits in the developing piglet hippocampus and brainstem medulla, and how prior nicotine exposure alters the response to acute IHH. Five piglet groups included: 1day IHH (1D IHH, n=9), 4days IHH (4D IHH, n=8), controls exposed only to air cycles for 1day (1D Air, n=6) or 4days (4D Air, n=5), and pre-exposed to nicotine for 13days prior to 1day IHH (Nic+1D IHH, n=7)...
February 21, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28231479/intermittent-bilateral-coherence-in-physiological-and-essential-hand-tremor
#19
Soma Chakraborty, Jana Kopecká, Otakar Šprdlík, Martina Hoskovcová, Olga Ulmanová, Evžen Růžička, Martin Zapotocky
OBJECTIVE: To investigate the prevalence and the temporal structure of bilateral coherence in physiological (PT) and essential (ET) hand tremor. METHODS: Triaxial accelerometric recordings from both hands in 30 healthy subjects and 34 ET patients were analyzed using spectral coherence and wavelet coherence methods. In 12 additional healthy subjects, the relation between the hand tremor and the chest wall acceleration was evaluated using partial coherence analysis...
January 14, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28230741/high-frequency-repetitive-transcranial-magnetic-stimulation-rtms-improves-functional-recovery-by-enhancing-neurogenesis-and-activating-bdnf-trkb-signaling-in-ischemic-rats
#20
Jing Luo, Haiqing Zheng, Liying Zhang, Qingjie Zhang, Lili Li, Zhong Pei, Xiquan Hu
Repetitive transcranial magnetic stimulation (rTMS) has rapidly become an attractive therapeutic approach for stroke. However, the mechanisms underlying this remain elusive. This study aimed to investigate whether high-frequency rTMS improves functional recovery mediated by enhanced neurogenesis and activation of brain-derived neurotrophic factor (BDNF)/tropomyosin-related kinase B (TrkB) pathway and to compare the effect of conventional 20 Hz rTMS and intermittent theta burst stimulation (iTBS) on ischemic rats...
February 20, 2017: International Journal of Molecular Sciences
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