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Janete de Souza Urbanetto, Ana Paula Christo de Freitas, Ana Paula Ribeiro de Oliveira, Jessica de Cassia Ramos Dos Santos, Franciele de Oliveira Minuto Muniz, Renata Martins da Silva, Maria Cristina Lore Schilling
OBJECTIVE: To describe the scientific evidence published in literature regarding the risk factors for the development of phlebitis. METHOD: Integrative literature review with the inclusion of 14 original articles found in the LILACS, Scielo and Pubmed bases from January 2004 to April 2015, analyzed by levels of evidence and frequency, associated factors, degree and treatment of phlebitis. RESULTS: The frequency / incidence / minimum rate of phlebitis was 3% and the maximum was 59...
June 7, 2018: Revista Gaúcha de Enfermagem
Eniko Szakmar, Colin J Morley, Gusztav Belteki
OBJECTIVES: To investigate how compensating for endotracheal tube leaks by targeting the leak-compensated tidal volume affects measured physiologic and ventilator variables during neonatal mechanical ventilation. DESIGN: Retrospective observational study. SETTING: A level III Neonatal ICU. PATIENTS: We enrolled 30 neonates who were ventilated using synchronized intermittent positive pressure mode with volume guarantee and had at least 12 hours of continuous detailed recording of ventilation variables...
June 21, 2018: Pediatric Critical Care Medicine
Tracy L Baker, Stephen M Johnson, Jyoti J Watters
No abstract text is available yet for this article.
June 19, 2018: Respiratory Physiology & Neurobiology
Samuel J Smith, Anitta R Y Kamara, Foday Sahr, Mohamed Samai, Alpha S Swaray, Didier Menard, Marian Warsame
Currently, the national malaria control programme (NMCP) of Sierra Leone recommends artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) as first- and second-line treatment for uncomplicated malaria, respectively, and artesunate + sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment during pregnancy and for infants. In 2016, the NMCP conducted a study to assess the clinical and parasitological responses of children under five years to ASAQ, AL and dihydroartemisinin-piperaquine (DHA/PPQ) according to the WHO protocol...
June 19, 2018: Acta Tropica
Hiroshi Takasaki, Stephen May
BACKGROUND: In Mechanical Diagnosis and Therapy (MDT), patients with low back pain (LBP) are classified into subgroups to guide a management strategy. A common subgroup where symptoms improve with lumbar extension is labeled posterior derangement syndrome. A less common subgroup where symptoms improve with lumbar flexion is labeled anterior derangement syndrome. CASE PRESENTATION: The patient was a 23-year-old woman with intermittent LBP and discomfort over the left lower extremity was initially diagnosis with posterior derangement syndrome...
June 22, 2018: Physiotherapy Theory and Practice
Claus G Roehrborn, Martin M Miner, Richard Sadovsky
In this review, we focus on current trends in the management of male lower urinary tract symptoms (LUTS), defined here as LUTS, namely, storage, voiding, and post-micturition symptoms presumed secondary to benign prostatic hyperplasia (BPH), and discuss possible novel approaches toward better care. According to results of a PubMed database search covering the last 10 years and using keywords pertaining to male LUTS, this condition continues to be globally undiagnosed or diagnosed late, partly because of men's hesitation to seek help for perceived embarrassing problems or problems considered a normal part of aging...
June 22, 2018: Postgraduate Medicine
Julia Thumfart, Steffen Wagner, Anuradha Jayanti, Dominik Müller, Wolfgang Pommer
AIMS: Intensified hemodialysis (HD) programs have been developed to overcome the shortcomings of conventional HD. However, there are no data on the implementation of intensified HD programs into routine care. Therefore, we investigated the attitude of nephrologists towards intensified HD, its penetrance into clinical practice, and barriers to implementation. MATERIALS AND METHODS: We performed an online survey within the German Society of Nephrology on the beliefs and attitudes towards intensified HD...
June 22, 2018: Clinical Nephrology
Zhipeng Liu, Silin Huang, Zhengyu Chen, Xinying Wang
Lymphoid follicular proctitis (LFP) is an uncommon inflammatory disease that is characterized by rectal bleeding, congested and granular mucosa without ulceration and abnormal and coalescing hyperplastic lymphoid follicles without acute inflammatory changes. The lesions are usually confined to the rectal mucosa. LFP therapy is not well defined. Herein, we present a case of LFP that was resolved with a rapid administration of mesalazine enemas. A 35-year-old male was admitted to our hospital due to intermittent rectal bleeding associated with stools...
June 22, 2018: Revista Española de Enfermedades Digestivas
Francis Grover, Maurice Lamb, Scott Bonnette, Paula L Silva, Tamara Lorenz, Michael A Riley
Tightly coordinated grip force adaptations in response to changing load forces have been reported as continuous, stable, and proportional to the load force changes. Considering the existence of inherent sensorimotor feedback delays, current accounts of grip force-load force coupling invoke explicit predictive mechanisms in the form of internal models for feedforward control to account for anticipatory grip force modulations. However, recent findings suggest that the stability and regularity of grip force-load force coupling is less persistent than previously thought...
June 22, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Junpeng Liu, Jiajia Zhu, Fei Yuan, Xuejun Zhang, Quan Zhang
BACKGROUND: Idiopathic or classical trigeminal neuralgia (TN) is a chronic painful condition characterized by intermittent pain attacks. Enough evidence demonstrates classical TN is related to neurovascular compression (NVC) at the trigeminal root entry zone (REZ), but white matter change secondary to TN are not totally known. METHODS: Visual Analogue Scale (VAS) and diffusion tensor imaging were performed on 29 patients with right TN and 35 healthy individuals...
June 22, 2018: Journal of Headache and Pain
Takashige Yamada, Hiromasa Nagata, Shizuko Kosugi, Takeshi Suzuki, Hiroshi Morisaki, Yoshifumi Kotake
BACKGROUND: Both anesthetic-induced and ischemic preconditioning are protective against hepatic ischemia-reperfusion injury. However, the effects of these preventive methods on the metabolic function remain to be elucidated. We investigated the anesthetic conditioning and ischemic preconditioning on the metabolic function of the rabbit model of hepatic ischemia-reperfusion. METHODS: After approval by the institutional animal care and use committee, 36 Japanese White rabbits underwent partial hepatic ischemia for 90 min either under sevoflurane or propofol anesthesia...
June 21, 2018: Journal of Anesthesia
Andrea Porzionato, Elena Stocco, Diego Guidolin, Luigi Agnati, Veronica Macchi, Raffaele De Caro
In the carotid body (CB), a wide series of neurotransmitters and neuromodulators have been identified. They are mainly produced and released by type I cells and act on many different ionotropic and metabotropic receptors located in afferent nerve fibers, type I and II cells. Most metabotropic receptors are G protein-coupled receptors (GPCRs). In other transfected or native cells, GPCRs have been demonstrated to establish physical receptor-receptor interactions (RRIs) with formation of homo/hetero-complexes (dimers or receptor mosaics) in a dynamic monomer/oligomer equilibrium...
2018: Frontiers in Physiology
Victoria Flexer, Celso Fernando Baspineiro, Claudia Inés Galli
The electrification of our world is driving a strong increase in demand for lithium. Energy storage is paramount in electric and hybrid vehicles, in green but intermittent energy sources, and in smart grids in general. Lithium is a vital raw material for the build-up of both currently available lithium-ion batteries, and prospective next generation batteries such as lithium-air and lithium sulphur. The continued availability of lithium can only rely on a strong increase of mining and ore processing. It would be an inconsistency if the increased production of lithium for a more sustainable society would be associated with non-sustainable mining practices...
October 15, 2018: Science of the Total Environment
Michael Tradewell, Joseph J Pariser, Tony Nimeh, Sean P Elliott
Urinary tract infection (UTI) is a source of morbidity and healthcare costs in adults with spina bifida (ASB). UTI prevention strategies are often recommended, but the evidence of various approaches remains unclear. We performed a systematic review to inform a best practice policy statement for UTI prevention in ASB. On behalf of the Neurogenic Bladder Research Group (, we developed an a priori protocol and searched the published English literature for 30 outcomes questions addressing UTI prevention in ASB...
May 2018: Translational Andrology and Urology
Michiko Honda, Akira Tsuchiya, Wataru Isono, Mikiko Takahashi, Akihisa Fujimoto, Masashi Kawamoto, Osamu Nishii
In order to diagnose endometrial cancer preoperatively, outpatient endometrial biopsy with a curette is frequently performed owing to its convenience. However, in some cases, gynecologists fail to diagnose endometrial cancer via outpatient endometrial biopsy because of the cancer's distribution in the uterus and its consistency. A 57-year-old Japanese woman (gravida 4 para 4) presented with a 6-month history of light but intermittent postmenopausal vaginal bleeding. A malignant uterine tumor was strongly suspected after imaging using ultrasound examination and magnetic resonance imaging; however, a precise pathological diagnosis was not achieved despite multiple outpatient endometrial biopsies with the aid of office hysteroscopy...
May 2018: Case Reports in Oncology
Jamil Shah, Abul Shahidullah
Intestinal parasitic infections are a major public health issue across the world and particularly in rural and urban areas of tropical and subtropical countries. Those at increased risk include inhabitants of poor and disadvantaged regions, which are more likely to have inadequate environmental sanitation, insufficient water supply, greater contact rates with reservoirs of infection, limited health literacy, and socioeconomic disparities. Of the intestinal nematodes (roundworms) that parasitize the human gastrointestinal tract, Ascaris lumbricoides is the largest in terms of size...
May 2018: Case Reports in Gastroenterology
Maithe Cardoso de Araújo, Christian Baumgart, Christian T Jansen, Jürgen Freiwald, Matthias W Hoppe
Cardoso de Araújo, M, Baumgart, C, Jansen, CT, Freiwald, J, and Hoppe, MW. Sex differences in physical capacities of German Bundesliga soccer players. J Strength Cond Res XX(X): 000-000, 2018-Sex differences in physical capacities of elite soccer players have received limited attention. Therefore, this study investigated sex differences in linear and nonlinear sprint, squat and countermovement jump, core endurance, as well as incremental and intermittent endurance capacities in German Bundesliga soccer players...
June 20, 2018: Journal of Strength and Conditioning Research
Shayan Abtahi, Erin Howell, Paul J Currie
The present study investigated the relationship between accumbal ghrelin and glucagon-like peptide 1 (GLP-1) signaling in alcohol reward in female rats. Animals with guide cannulae targeting the nucleus accumbens core (NAcC) and shell (NAcS) were habituated to alcohol for 12 weeks through a two-bottle intermittent access paradigm. JMV2959, a ghrelin antagonist, and exendin-4 (Ex-4), a GLP-1 agonist, were microinjected at the onset of the nocturnal cycle. Alcohol, food, water, and total fluid intake were measured 2, 6, and 24 h postinjection...
June 20, 2018: Neuroreport
Eugenia B Manukhina, Vadim E Tseilikman, Olga B Tseilikman, Maria V Komelkova, Marina V Kondashevskaya, Anna V Goryacheva, Maxim S Lapshin, Pavel O Platkovskii, Anatoly V Alliluev, H Fred Downey
Non-pharmacological treatments of stress-induced disorders are promising, since they enhance endogenous stress defense systems and have few contraindications and side effects. This study tested a hypothesis that intermittent hypoxia conditioning (IHC) ameliorates behavioral, biochemical, and morphological signs of experimental PTSD induced in rats using a model of predator stress (10-day exposure to cat urine scent, 15 min daily followed by 14 days of stress-free rest). After the last day of stress exposure, rats were conditioned in an altitude chamber for 14 days at a 1,000 m simulated altitude for 30 min on day 1 with progressively increasing the altitude and duration to 4,000 m for 4 hours on day 5...
June 21, 2018: Journal of Applied Physiology
Mamitaro Ohtsuki, Hiroshi Morimoto, Hidemi Nakagawa
Atopic dermatitis (AD) requires long-term management, mainly with topical anti-inflammatory agents. Topical corticosteroids (TCS) and tacrolimus ointment (TAC-O) are recommended as first-line treatments for AD. However, the long-term use of TCS is limited by cutaneous adverse events such as skin atrophy. For TAC-O, Japanese and US labelings were updated in 2003 and 2006, respectively, to include a boxed warning about a theoretical risk of skin cancer and lymphoma in patients treated with topical calcineurin inhibitors...
June 21, 2018: Journal of Dermatology
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