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https://www.readbyqxmd.com/read/28817950/editorial-comment-on-end-2017-0350-or-r1
#1
Kristina L Penniston
Risk factors for coronary artery disease are relatively common among patients with urolithiasis. Increased risk of myocardial infarction and carotid atherosclerosis in young adults have been noted. The authors of this article on vascular disease and kidney stones make the case for using routine imaging studies to screen for patients with cardiovascular risk factors.
August 17, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28816298/-multiple-endoscopy-for-the-treatment-of-upper-urinary-tract-calculi-following-ileal-conduit-a-case-report-and-literature-review
#2
B Wang, J F Ye, L Zhao, H Bi, J Lu, L L Ma
Upper urinary tract calculi with infection is a quite difficult acute urologic emergency. And what is more, upper urinary tract obstruction after radical cystectomy following urinary diversion may be fatal in the vulnerable patients with this kind of situation. Postoperative anatomy and other factors affect the upper urinary tract calculi, and urinary tract infection greatly increased the risk. But it is particularly difficult to handle with patients with poor general condition and septic shock treatment, so how to optimize the selection program is worth further studying...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28812535/associating-mutations-causing-cystinuria-with-disease-severity-with-the-aim-of-providing-precision-medicine
#3
Henry J Martell, Kathie A Wong, Juan F Martin, Ziyan Kassam, Kay Thomas, Mark N Wass
BACKGROUND: Cystinuria is an inherited disease that results in the formation of cystine stones in the kidney, which can have serious health complications. Two genes (SLC7A9 and SLC3A1) that form an amino acid transporter are known to be responsible for the disease. Variants that cause the disease disrupt amino acid transport across the cell membrane, leading to the build-up of relatively insoluble cystine, resulting in formation of stones. Assessing the effects of each mutation is critical in order to provide tailored treatment options for patients...
August 11, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28808392/antiurolithiatic-effect-of-sirupeelai-samoola-kudineer-a-polyherbal-siddha-decoction-on-ethylene-glycol-induced-renal-calculus-in-experimental-rats
#4
A Hannah Rachel Vasanthi, V Muthulakshmi, V Gayathri, R Manikandan, S Ananthi, Sarah Kuruvilla
BACKGROUND: Sirupeelai Samoola Kudineer (SK), a polyherbal decoction containing four medicinal plants has been used in Siddha system of medicine, practiced in Southern parts of India for the management of urolithiasis. OBJECTIVE: The present study is carried out to scientifically validate the traditional claim and to study the mechanism of action of the drug. MATERIALS AND METHODS: In the present study, anti-urolithiatic effect of SK was evaluated in Sprague-Dawley rats using ethylene glycol through drinking water and intraperitoneal injection of sodium oxalate...
July 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28808281/surveillance-bias-in-cancer-risk-after-unrelated-medical-conditions-example-urolithiasis
#5
Kari Hemminki, Otto Hemminki, Asta Försti, Kristina Sundquist, Jan Sundquist, Xinjun Li
We analysed cancer risks in patients with urinary tract stones but some features of the generated results alarmed us about possible surveillance bias, which we describe in this report. We used nationwide Swedish hospital records to identify patients with urinary tract stones (N = 211,718) and cancer registration data for cancer patients for years 1987 to 2012. Standardized incidence ratios (SIRs) for cancer were calculated after the last medical contact for urinary tract stones. All cancers were increased after kidney (SIR 1...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28802643/update-on-urinary-stones-in-children-current-and-future-concepts-in-surgical-treatment-and-shockwave-lithotripsy
#6
REVIEW
Mesrur Selcuk Silay, Jonathan S Ellison, Thomas Tailly, Paolo Caione
CONTEXT: Miniaturized instrumentation used for endoscopic treatment of urinary stone disease in children has been readily adopted in clinical practice. However, there is a need to optimize and individualize the surgical approach according to the patient's age, body habitus, and stone characteristics. Promising novel equipment and techniques will continue to advance the surgical care of these children. OBJECTIVE: To review the literature regarding surgical and shockwave lithotripsy (SWL) treatment of urinary stone disease in children and provide an overview on future treatment innovations...
August 9, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28802568/the-application-of-suctioning-flexible-ureteroscopy-with-intelligent-pressure-control-in-treating-upper-urinary-tract-calculi-on-patients-with-a-solitary-kidney
#7
Jianrong Huang, Donghua Xie, Ruiping Xiong, Xiaolin Deng, Chengbing Huang, Difu Fan, Zuofeng Peng, Wen Qin, Min Zeng, Leming Song
OBJECTIVE: To investigate the usage of intelligently pressure-controlled flexible ureteroscopy (URS) in managing upper urinary tract calculi in patients with a solitary kidney. METHODS: Forty patients with a solitary kidney and upper urinary tract calculus were included in this study. All the patients underwent suctioning URS with intelligent control of renal pelvic pressure by connecting pressure-measuring suctioning ureteral access sheath to an irrigation and suctioning platform...
August 9, 2017: Urology
https://www.readbyqxmd.com/read/28801219/renal-forniceal-rupture-is-conservative-management-safe
#8
Tara Nikonow Morgan, Jathin Bandari, Mohammed Shahait, Timothy Averch
OBJECTIVE: To outline treatment considerations and outcomes for a cohort of patients with forniceal rupture with the aim of adding to a very limited body of literature regarding clinical practice in this area. METHODS: We retrospectively searched all radiographic records for patients treated at our institution between January 2009 and January 2016 with forniceal rupture. We compiled demographic data, etiology, clinical factors, treatments and outcomes. RESULTS: Of the 103 patients analyzed, the median age at presentation was 64 years (IQR 52-73) and 56 (54%) were female...
August 8, 2017: Urology
https://www.readbyqxmd.com/read/28798825/ex-vivo-ureteroscopy-of-deceased-donor-kidneys
#9
Graham L Machen, Preston A Milburn, Patrick S Lowry, Jacqueline A Lappin, Debra K Doherty, Marawan M El Tayeb
INTRODUCTION: When encountered, the ideal management of lithiasis in deceased donor kidneys is not well-defined. With advances in endourological techniques, minimally invasive treatments are becoming an increasingly viable option. We set out to describe our experience performing ex-vivo ureteroscopy on cadaveric donor kidneys, including one in which the procedure was completed on-pump. METHODS: A retrospective chart review was undertaken to identify patients who had undergone ex-vivo ureteroscopy prior to cadaveric renal transplant...
August 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28794602/spontaneous-rupture-of-the-renal-pelvis-due-to-obstruction-of-pelviureteric-junction-by-renal-stone-a-case-report-and-review-of-the-literature
#10
Fatih Yanaral, Arif Ozkan, Nusret Can Cilesiz, Baris Nuhoglu
Spontaneous rupture of the urinary collecting system with extravasation of the urine is a very rare condition. This situation is commonly associated with an obstructing urinary stone. Herein, we report a case of an 86-year-old patient who has admitted to the emergency service with left flank pain continuing for 7 days and pain has exacerbated in the past 24 h. The patient had nausea, vomiting, and tenderness on the left side of the abdomen and left flank region. The patient was diagnosed with an 8 mm left kidney stone a month ago, and hydration and oral analgesics were recommended to the patient...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28794595/prevalence-of-diabetes-mellitus-after-extra-corporeal-shock-wave-lithotripsy-in-15-years-follow-up
#11
Fahimeh Kazemi Rashed, Nader Rash Ahmadi, Ali Zolfaghari, Alireza Farshi, Mohsen Amjadi, Mahboobeh Gholipour
OBJECTIVE: To investigate the hypothesis that extracorporeal shock wave lithotripsy (ESWL) increases the risk of new onset diabetes mellitus (DM) or significant changes in fasting blood sugar (FBS). MATERIALS AND METHODS: A total number of 307 patients enrolled in this study. All of them had undergone ESWL for kidney stone from 1991 to 1994. In 2009, after 15-19 years, we invited patients to check their blood sugar. RESULTS: There were 307 patients, 19...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28794593/laparoscopic-assisted-percutaneous-nephrolithotomy-in-chronic-kidney-disease-patients-with-ectopic-pelvic-kidney
#12
Sujata K Patwardhan, Umesh Ravikant Shelke, Bhushan P Patil, Yash R Pamecha
PURPOSE: Patients with deranged renal functions have a number of associated factors which can impair healing of wound and increase postoperative morbidity. This study was conducted to assess the problems while managing ectopic pelvic kidney calculi using laparoscopic approach for percutaneous nephrolithotomy (PCNL) in chronic kidney disease patients. SUBJECTS AND METHODS: Patients with calculi in ectopic kidney with increased serum creatinine level secondary to obstruction were included in the study...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28792520/comparison-of-porous-and-nano-zinc-oxide-for-replacing-high-dose-dietary-regular-zinc-oxide-in-weaning-piglets
#13
Lina Long, Jiashun Chen, Yonggang Zhang, Xiao Liang, Hengjia Ni, Bin Zhang, Yulong Yin
The aim of this study was to compare the effect of dietary supplementation with low dose of porous and nano zinc oxide (ZnO) on weaning piglets, and to evaluate the possibility of using them as an alternative to high dose of regular ZnO. Piglets were randomly allocated into four treatment groups fed with four diets: (1) basal diet (NC), (2) NC+ 3000 mg/kg ZnO (PC), (3) NC + 500 mg/kg porous ZnO (HiZ) and (4) NC + 500 mg/kg nano ZnO (ZNP). The result showed that piglets in HiZ group had less diarrhea than ZNP group (P < 0...
2017: PloS One
https://www.readbyqxmd.com/read/28792192/early-term-effect-of-ureterorenoscopy-urs-on-the-kidney-research-measuring-ngal-kim-1-fabp-and-cys-c-levels-in-urine
#14
Erdal Benli, Sema Nur Ayyildiz, Selma Cirrik, Tevfik Noyan, Ali Ayyildiz, Abdullah Cirakoglu
AIM: URS is a very commonly used procedure for treatment of ureter stones. Increased hydrostatic pressure in the collecting system linked to fluids used during the procedure may cause harmful effects on the kidney. The aim of this study is to determine whether the URS procedure has a negative effect on the kidney by investigating NGAL, KIM-1, FABP and Cys C levels in urine. MATERIAL AND METHODS: This study included 30 patients undergoing ureterorenoscopy (URS) for ureter stones...
August 8, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28792186/quality-of-life-and-urolithiasis-the-patient-reported-outcomes-measurement-information-system-promis
#15
Nishant Patel, Robert D Brown, Carl Sarkissian, Shubha De, Manoj Monga
BACKGROUND: With a high rate of recurrence, urolithiasis is a chronic disease that impacts quality of life. The Patient Reported Outcomes Measurement Information System is an NIH validated questionnaire to assess patient quality of life. We evaluated the impact of urolithiasis on quality of life using the NIH-sponsored PROMIS-43 questionnaire. MATERIALS AND METHODS: Patients reporting to the kidney stone clinic were interviewed to collect information on stone history and demographic information and were asked to complete the PROMIS-43 questionnaire...
August 8, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28782573/percutaneous-nephrolithotomy-in-solitary-kidneys-17-years-of-experience
#16
Hakan Bahadır Haberal, Burak Çitamak, Ali Cansu Bozaci, Mustafa Sertaç Yazici, Fazıl Tuncay Aki, Cenk Yücel Bilen
OBJECTIVE: To compare demographics and results of patients underwent percutaneous nephrolithotomy (PCNL) with solitary and bilateral kidneys. MATERIALS AND METHODS: Between January 1998 and August 2014, 2268 patients underwent PCNL at Hacettepe University Hospital. We retrospectively analyzed the data of 91 patients with a solitary kidney and 2177 patients with bilateral kidneys treated by PCNL. We compared the success and complication rates between solitary and bilateral kidney patients...
August 3, 2017: Urology
https://www.readbyqxmd.com/read/28782352/cornus-mas-a-review-on-traditional-uses-and-pharmacological-properties
#17
Fatemeh Hosseinpour-Jaghdani, Tahoora Shomali, Sajedeh Gholipour-Shahraki, Mohammad Rahimi-Madiseh, Mahmoud Rafieian-Kopaei
Medicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties. Cornus mas L. (Cornelian cherry) is one of these medicinal plants with high level of antioxidant activity. Cornelian cherry is an attractive ornamental plant with delicious fruit having nutritional and therapeutic values. The main purpose of this paper is to present and summarize the pharmacological and therapeutic effects from researches done on Cornelian cherry in studies from 2000 to 2016...
March 31, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28781372/uromodulin-from-physiology-to-rare-and-complex-kidney-disorders
#18
REVIEW
Olivier Devuyst, Eric Olinger, Luca Rampoldi
Uromodulin (also known as Tamm-Horsfall protein) is exclusively produced in the kidney and is the most abundant protein in normal urine. The function of uromodulin remains elusive, but the available data suggest that this protein might regulate salt transport, protect against urinary tract infection and kidney stones, and have roles in kidney injury and innate immunity. Interest in uromodulin was boosted by genetic studies that reported involvement of the UMOD gene, which encodes uromodulin, in a spectrum of rare and common kidney diseases...
September 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28776078/sarna-mediated-activation-of-trpv5-reduces-renal-calcium-oxalate-deposition-in-rat-via-decreasing-urinary-calcium-excretion
#19
Tao Zeng, Xiaolu Duan, Wei Zhu, Yang Liu, Wenqi Wu, Guohua Zeng
Hypercalciuria is a main risk factor for kidney stone  formation. TRPV5 is the gatekeeper protein for mediating calcium transport and reabsorption in the kidney. In the present study, we tested the effect of TRPV5 activation with small activating RNA (saRNA), which could induce gene expression by targeting the promoter of the gene, on ethylene glycol (EG)-induced calcium oxalate (CaOx) crystals formation in rat kidney. Five pairs of RNA activation sequences targeting the promoter of rat TRPV5 were designed and synthesized...
August 3, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28775336/shape-dependent-cellular-toxicity-on-renal-epithelial-cells-and-stone-risk-of-calcium-oxalate-dihydrate-crystals
#20
Xin-Yuan Sun, Jian-Ming Ouyang, Kai Yu
Renal epithelial cell injury causes crystal retention and leads to renal stone formation. However, the effects of crystal shape on cell injury and stone risk remain unclear. This study compared the cytotoxicity degrees of calcium oxalate dihydrate (COD) crystals having different shapes toward human kidney proximal tubular epithelial (HK-2) cells to reveal the effect of crystal shape on cell injury and to elucidate the pathological mechanism of calcium oxalate kidney stones. The effects of exposure to cross-shaped (COD-CS), flower-like (COD-FL), bipyramid (COD-BD), and elongated-bipyramid (COD-EBD) COD crystals on HK-2 cells were investigated by examining the cell viability, cell membrane integrity, cell morphology change, intracellular reactive oxygen species, mitochondrial membrane potential (Δψm), and apoptotic and/or necrotic rate...
August 3, 2017: Scientific Reports
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