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https://www.readbyqxmd.com/read/28528955/potential-therapeutic-activity-of-phlogacanthus-thyrsiformis-hardow-mabb-flower-extract-and-its-biofabricated-silver-nanoparticles-against-chemically-induced-urolithiasis-in-male-wistar-rats
#1
Poppy Das, Kiran Kumar, Arunai Nambiraj, Reshma Rajan, Rajendra Awasthi, Kamal Dua, Himaja M
Urolithiasis is a painful disorder in which stones are formed in the kidney, bladder or urethra. There are no proper therapeutic treatments available for kidney stones and people suffering from larger stones have to undergo surgery which has many side effects. A natural remedy with therapeutic effects that can dissipate and remove even the larger stones would eliminate the need of a surgery and the risks associated with it. The flowers of Phlogacanthus thyrsiformis used in culinary recipes in the north eastern India are also widely used as a folklore medicine for the treatment of kidney stones and liver disorders...
May 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28522341/systemic-and-ocular-fluid-compounds-as-potential-biomarkers-in-age-related-macular-degeneration
#2
REVIEW
Eveline Kersten, Constantin C Paun, Rosa L Schellevis, Carel B Hoyng, Cécile Delcourt, Imre Lengyel, Tunde Peto, Marius Ueffing, Caroline C W Klaver, Sascha Dammeier, Anneke I den Hollander, Eiko K de Jong
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy. They can also be useful in clinical practice for monitoring disease progression, evaluation of treatment efficacy and risk assessment in multifactorial diseases, such as age-related macular degeneration (AMD). AMD is a highly prevalent progressive retinal disorder for which multiple genetic and environmental risk factors have been described, but the exact etiology is not yet fully understood. Many compounds have been evaluated for their association with AMD...
May 15, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28521550/detection-and-evaluation-of-renal-injury-in-burst-wave-lithotripsy-using-ultrasound-and-magnetic-resonance-imaging
#3
Philip Clark May, Wayne Kreider, Adam D Maxwell, Yak-Nam Wang, Bryan W Cunitz, Philip M Blomgren, Cynthia Johnson, Joshua Sh Park, Michael R Bailey, Donghoon Lee, Jonathan D Harper, Mathew D Sorensen
PURPOSE: Burst wave lithotripsy (BWL) is a transcutaneous technique with potential to safely and effectively fragment renal stones. Preclinical investigations of BWL require the assessment of potential renal injury. This study evaluates the capabilities of real-time ultrasound and magnetic resonance imaging (MRI) to detect and evaluate BWL injury that was induced in porcine kidneys. MATERIALS AND METHODS: Ten kidneys from five female farm pigs were treated with either a 170 kHz or 335 kHz BWL transducer using variable treatment parameters and monitored in real time with ultrasound...
May 18, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28520334/kidney-anatomy-three-dimensional-3d-printed-pelvicalyceal-system-models-of-the-collector-system-improve-the-diagnosis-and-treatment-of-stone-disease
#4
EDITORIAL
Luciano A Favorito
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28508979/urinothorax-in-a-child-secondary-to-obstructive-renal-stone-in-a-solitary-functioning-kidney-a-case-report
#5
Muhammad Waqas, Gul Nawaz, Avais Raja, Ijaz Hussain, Muhammad Waqas Iqbal
Urinothorax or presence of urine in pleural cavity is a highly unusual cause of pleural effusion. It is most commonly secondary to genitourinary trauma and obstructive uropathy. We here by present a case of urinothorax secondary to renal stone disease in a 5-year-old child with a solitary functioning kidney.
November 2016: CEN Case Reports
https://www.readbyqxmd.com/read/28508108/stone-in-ectopic-pelvic-pancake-kidney-a-surgical-challenge-overcome-by-robotic-surgery
#6
Santosh Kumar, Kshitij Bishnoi, Vikas Kumar Panwar, Adarsh Kumar, Manjeet Kumar Sharma
No abstract text is available yet for this article.
May 15, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28506053/-laparoscopic-pyelolithotomy-in-a-horseshoe-kidney-a-case-report-and-review-of-the-literature
#7
Tateki Yoshino, Koji Wake, Tomoyuki Sugitani, Koji Kodama, Hiroaki Shiina, Hiroaki Yasumoto, Ayumi Kadowaki, Kazuo Kawakami
A 76-year-old man was introduced to our department with a right kidney stone. On the basis of further examination, he was diagnosed with a 23 mm right kidney stone accompanied with a horseshoe kidney. Retrograde pyelography and diuretic renogram revealed a non-obstructed right ureteropelvic junction. Finally, we chose laparoscopic pyelolithotomy via peritoneal approach because the stone was large and accompanied with a horseshoe kidney. The surgery took 165 minutes and the estimated blood loss was 25 ml. There were no minor or major complications...
April 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28502039/possible-involvement-of-the-lipoxygenase-and-leukotriene-signaling-pathways-in-cisplatin-mediated-renal-toxicity
#8
Osama A Alkhamees, Abdulaziz S Alroujayee, Hatem M Abuohashish, Fatima S Alrojayee, Mohammed M Ahmed
PURPOSE: The present study examined the possible involvement of the lipoxygenase (LOX) pathway in cisplatin (CPT)-induced nephrotoxicity. METHODS: Wistar albino rats were challenged with CPT IP injection (7.5 mg/kg) and were sacrificed after one week. Signs of renal dysfunction, including urea and creatinine clearance levels and renal histological structure, were investigated. Gene and protein expression levels of different LOX pathway enzymes and products, including 5-LOX, 12-LOX, 15-LOX, 5-LOX activating protein (FLAP), leukotriene A4 hydrolase (LTA4 hydrolase), leukotriene C4 synthase (LTC4 synthase), LTB4 receptor, and cysteinyl (cys) LT receptor types 1 and 2, were also determined in the kidneys using real-time PCR and western blotting, respectively...
May 13, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28496123/systematic-evaluation-for-effects-of-urine-ph-on-calcium-oxalate-crystallization-crystal-cell-adhesion-and-internalization-into-renal-tubular-cells
#9
Juthatip Manissorn, Kedsarin Fong-Ngern, Paleerath Peerapen, Visith Thongboonkerd
Urine pH has been thought to be an important factor that can modulate kidney stone formation. Nevertheless, there was no systematic evaluation of such pH effect. Our present study thus addressed effects of differential urine pH (4.0-8.0) on calcium oxalate (CaOx) crystallization, crystal-cell adhesion, crystal internalization into renal tubular cells, and binding of apical membrane proteins to the crystals. Microscopic examination revealed that CaOx monohydrate (COM), the pathogenic form, was crystallized with greatest size, number and total mass at pH 4...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28495592/mir-21-promotes-fibrogenesis-in-peritoneal-dialysis
#10
Melisa Lopez-Anton, Mark Lambie, Manuel Lopez-Cabrera, Claus P Schmitt, Vicente Ruiz-Carpio, Maria Bartosova, Betti Schaefer, Simon Davies, Timothy Stone, Robert Jenkins, Philip R Taylor, Nicholas Topley, Timothy Bowen, Donald Fraser
Peritoneal dialysis (PD) is a life-saving form of renal replacement therapy for those with end-stage kidney disease. Mesothelial cells (MCs) line the peritoneal cavity and help define peritoneal response to treatment-associated injury, a major reason for treatment failure. miRNAs are important regulators, but their roles in peritoneal fibrosis are largely unknown. In this study, miR-21 was one of the most abundant miRNAs in primary MCs, and was up-regulated by the profibrotic cytokine transforming growth factor-β1 and in PD effluent-derived MCs exhibiting mesenchymal phenotypic change...
May 8, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28495480/-fabien-arcelin-1876-1942-or-how-to-become-a-radiation-oncologist-when-born-an-archeologist
#11
N Foray
Fabien Arcelin, physician working in Lyon, pioneer of radiology and radiotherapy, was both mentored by Destot (one of the fathers of the French radiology for his thesis of medicine) and by his own father Adrien Arcelin (one of the two codiscoverers of the prehistorical site of the Roche-de-Solutré in Burgundy) for archeological works. Hence, radiologist in Lyon during the week and archeologist during the weekend, Fabien Arcelin made significant advances in both radiation research and archeology. He was notably the discoverer of the first tombs of Aurignacian men...
May 8, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28491855/nephrolithiasis-in-elderly-population-effect-of-demographic-characteristics
#12
Emadoddin Moudi, Seyed Reza Hosseini, Ali Bijani
BACKGROUND: Kidney stone (nephrolithiasis) is one of the most common diseases. During the past several decades, its prevalence and incidence have increased markedly in elderly population. OBJECTIVES: This study was conducted to evaluate the risk factors for nephrolithiasis in elderly population. PATIENTS AND METHODS: This study was based on the Amirkola Health and Ageing Project (AHAP). Elderly people with kidney stones in every size, type and number were considered to be the case group and other subjects without a history of kidney stones served as control group...
March 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28491341/validation-of-the-kidney-failure-risk-equation-in-manitoba
#13
Reid H Whitlock, Mariette Chartier, Paul Komenda, Jay Hingwala, Claudio Rigatto, Randy Walld, Allison Dart, Navdeep Tangri
BACKGROUND: Patients with chronic kidney disease (CKD) are at risk to progress to kidney failure. We previously developed the Kidney Failure Risk Equation (KFRE) to predict progression to kidney failure in patients referred to nephrologists. OBJECTIVE: The objective of this study was to determine the ability of the KFRE to discriminate which patients will progress to kidney failure in an unreferred population. DESIGN: A retrospective cohort study was conducted using administrative databases...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28482898/ethnopharmacological-survey-of-medicinal-plants-practiced-by-traditional-healers-and-herbalists-for-treatment-of-some-urological-diseases-in-the-west-bank-palestine
#14
Nidal Amin Jaradat, Abdel Naser Zaid, Rowa Al-Ramahi, Malik A Alqub, Fatima Hussein, Zakaria Hamdan, Mahmoud Mustafa, Mohammad Qneibi, Iyad Ali
BACKGROUND: Throughout history, every civilization in the world used plants or their derivatives for treatment or prevention of diseases. In Palestine as in many other countries, herbal medicines are broadly used in the treatment of wide range of diseases including urological diseases. The main objective of this research is to study the use of herbal remedies by herbalists and traditional healers for treatment of various urological diseases in the West Bank regions of Palestine and to assess their efficacy and safety through the literature review of the most cited plants...
May 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28480748/effect-of-fruit-extract-on-renal-stone-formation-and-kidney-injury-in-rats
#15
Nasrin Partovi, Mohammad Reza Ebadzadeh, S Jamilaldin Fatemi, Mohammad Khaksari
This study investigated the effect of oral administration of Cactus fruit extracts on calcium oxalate deposition, malondialdehyde (MDA) and superoxide dismutase (SOD) activity in rat model. About 42 rats were used for the study. The animals were divided into seven groups. Control group maintained on regular rat food and drinking water throughout the study period, whereas in other groups nephrolithiasis was induced by ethylene glycol. Rats in kidney stone group were sacrificed after 28 days and all remaining groups after 58 days...
May 7, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28480348/antiurolithic-effect-of-olive-oil-in-a-mouse-model-of-ethylene-glycol-induced-urolithiasis
#16
Mohammed Alenzi, Shaik Rahiman, Bilal Ahmad Tantry
PURPOSE: At present, commercially available antiurolithic drugs have more adverse effects than potential therapeutic or preventive effects with chronic use. With this in mind, the present study was designed to assess the antiurolithic effect of olive oil in a mouse model of ethylene glycol (EG)-induced urolithiasis. MATERIALS AND METHODS: Adult albino mice were divided into 6 groups. Group I was fed the vehicle only. Group II was supplemented with 0.75% EG alone in drinking water during the experimental period to initiate deposition of calcium oxalate in kidneys, which leads to urolithiasis in animals...
May 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28480343/evaluation-of-the-effect-of-bernoulli-maneuver-on-operative-time-during-mini-percutaneous-nephrolithotomy-a-prospective-randomized-study
#17
Nariman Gadzhiev, Brovkin Sergei, Vladislav Grigoryev, Zhamshid Okhunov, Arvind Ganpule, Aleksei Pisarev, Yerbol Iskakov, Sergei Petrov
PURPOSE: To evaluate the effect of 'Bernoulli maneuver' (bringing the access sheath to horizontal plane) on operative time and stone free rates in patients undergoing mini-percutaneous nephrolithotomy (PCNL). MATERIALS AND METHODS: All consecutive patients with a solitary kidney stone undergoing a mini-PCNL between 2015 and 2016 were included into this study. Patients were randomized either to standard prone or control (C) group patients or to tilted prone with 'Bernoulli maneuver' group (B) patients...
May 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28479771/laparoscopic-assisted-mini-percutaneous-nephrolithotomy-for-treatment-of-large-calculi-in-pelvic-ectopic-kidney
#18
Ketan P Vartak, Prashant H Salvi
We report two cases of male patients with pelvic ectopic kidney with large stones cleared with laparoscopic-assisted minimally invasive percutaneous nephrolithotomy (Mini-PERC) and holmium laser. These are the first cases of Mini-PERC done for pelvic ectopic kidney reported thus far.
April 2017: Urology Annals
https://www.readbyqxmd.com/read/28469318/significance-of-pigmented-urothelial-and-non-urothelial-cells-in-voided-urine-specimens-a-case-report-and-review
#19
Joseph Alan Kagan, Susan Wu, Svetoslav Bardarov
We present a case of metastatic malignant melanoma to the urinary bladder diagnosed on a voided urinary cytology specimen in a patient who visited the emergency department complaining of right flank pain, and dark urine. The patient reported having previous episodes of kidney stones. Additionally, more detailed clinical history obtained after the cytological diagnosis, revealed a previous excision of malignant melanoma on the back 10 years ago. The diagnosis of metastatic malignant melanoma was based solely on voided urine cytology...
April 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28466078/subcapsular-kidney-urinoma-after-percutaneous-nephrolithotomy
#20
Eugenio Di Grazia, Letterio D'Arrigo, Alberto Saita, Giuseppe Giordano, Giuseppe Russo, Giuseppe Morgia, Pasquale La Rosa
Background: A rare percutaneous nephrolithotomy (PCNL) complication and its management is reported. Case Presentation: A male patient, 43 years of age, underwent PCNL for a large left pyelocaliceal stone. Surgery was performed in the Valdivia-Galdakao supine position. The percutaneous tract was established by combined radiologic and sonographic guidance. The tract was dilated by balloon and a 24F Amplatz sheath was located. As complete clearance was not achieved because of a residual lower pole caliceal stone, a ureteral Double-J and a 20F nephrostomy were located for a second-look PCNL through the same tract after 7 days...
2017: Journal of Endourology Case Reports
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