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https://www.readbyqxmd.com/read/28938410/gender-difference-in-the-clinical-presentation-of-primary-hyperparathyroidism-influence-of-menopausal-status
#1
Elena Castellano, Roberto Attanasio, Alberto Boriano, Micaela Pellegrino, Francesca Garino, Laura Gianotti, Giorgio Borretta
Background: Female to male ratio in primary hyperparathyroidism (PHPT) is 3:1, but data on gender impact on the clinical presentation are limited. Methods: We evaluated retrospectively gender difference in biochemistry and clinical presentation at diagnosis in a monocentric series of 417 patients with PHPT: 93 men (58.6 ±14.5 years), and 324 women (61.7 ± 12.8 years), of whom 54 were pre-menopausal (pre-F) and 270 post-menopausal (post-F). Results: Men were significantly younger (p = 0...
September 7, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28937059/the-effect-of-an-educational-program-for-vascular-access-care-on-nurses-knowledge-at-dialysis-centers-in-khartoum-state-sudan
#2
Kalthoum Ibrahim Yousif, Hasan Abu-Aisha, Omar Ibrahim Abboud
End-stage renal disease is a worldwide problem that requires highly skilled nursing care. Hemodialysis (HD) is a corner-stone procedure in the management of most patients who require renal replacement therapy. Adequate vascular access is essential for the successful use of HD. Appropriate knowledge in taking care of vascular access is essential for minimizing complications and accurately recognizing vascular access-related problems. This study was to evaluate the effect of an educational program for vascular access care on nurses' knowledge at nine dialysis centers in Khartoum State...
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28923463/hyperparathyroidism
#3
REVIEW
John P Bilezikian, Leonardo Bandeira, Aliya Khan, Natalie E Cusano
Primary hyperparathyroidism is a common endocrine disorder of calcium metabolism characterised by hypercalcaemia and elevated or inappropriately normal concentrations of parathyroid hormone. Almost always, primary hyperparathyroidism is due to a benign overgrowth of parathyroid tissue either as a single gland (80% of cases) or as a multiple gland disorder (15-20% of cases). Primary hyperparathyroidism is generally discovered when asymptomatic but the disease always has the potential to become symptomatic, resulting in bone loss and kidney stones...
September 15, 2017: Lancet
https://www.readbyqxmd.com/read/28920816/urolithiasis-in-free-ranging-and-captive-otters-lutra-lutra-and-aonyx-cinerea-in-europe
#4
Monika Bochmann, Stephan Steinlechner, Albrecht Hesse, Hans Henrik Dietz, Heike Weber
Between 1996 and 1998, 477 dead otters from different Central European countries were examined for urolithiasis, including 449 free-ranging Eurasian otters (Lutra lutra) as well as 17 Eurasian otters and 11 Asian small-clawed otters (Aonyx cinerea) from captivity. In the free-ranging specimens, uroliths (sand or stones) were found in 105 animals (23.4%), with no significant difference (P = 0.77) between the sexes. Uroliths were not present in any juveniles (n = 26) and urolithiasis was not considered the main cause of death in any individual...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28914602/initial-clinical-experience-with-a-modulated-holmium-laser-pulse-moses-technology-does-it-enhance-laser-lithotripsy-efficacy
#5
Michael Mullerad, Jonatan R A Aguinaga, Tareq Aro, Alexander Kastin, Oleg Goldin, Alexander Kravtsov, Akram Assadi, Shadie Badaan, Gilad E Amiel
OBJECTIVE: The Lumenis(®) High-power Holmium Laser (120H) has a unique modulated pulse mode, Moses™ technology. Moses technology modulates the laser pulse to separate the water (vapor bubble), then deliver the remaining energy through the bubble. Proprietary laser fibers were designed for the Moses technology. Our aim was to compare stone lithotripsy with and without the Moses technology. METHODS: We designed a questionnaire for the urologist to fill immediately after each ureteroscopy in which the Lumenis 120H was used...
September 13, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28900827/lifetime-radiation-exposure-in-patients-with-recurrent-nephrolithiasis
#6
REVIEW
Mohamed A Elkoushy, Sero Andonian
Patients presenting with nephrolithiasis often undergo repeated imaging studies before, during, and after management. Considering the significant risk of stone recurrence in primary stone-formers, repeated imaging studies are not uncommon. Cumulative effects of ionizing radiation exposure from various imaging studies could potentially increase the risk for developing cataracts and solid malignancies in urolithiasis patients. Therefore, practitioners planning or performing imaging studies with ionizing radiation are compelled to keep radiation exposure to humans and the environment as low as possible, thus strictly adhering to the ALARA (As Low as Reasonably Achievable) principles...
September 12, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28900379/postmenopausal-hormone-and-the-risk-of-nephrolithiasis-a-meta-analysis
#7
Juan Yu, Binyan Yin
Menopause is reported to be associated with increased urinary calcium excretion, which may enhance the risk for the development of calcium kidney stones. However, it remains controversial about whether high level of postmenopausal hormone (PMH) is a risk factor for formation of nephrolithiasis. Several observational studies have shown that PMH is protective based on 24-hour urinary parameters. Recent clinical trials provided evidence to conclude that estrogen therapy increases the risk of nephrolithiasis in healthy postmenopausal women...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28894841/symptomatic-distal-ureteral-stone-in-an-ileal-ureter-treatment-by-combined-supine-ureteroscopy-and-mini-percutaneous-nephrolithotomy
#8
Florian Schott, Benedikt Becker, Andreas J Gross, Christopher Netsch
Urolithiasis is a well-known and common late complication in patients with urinary diversion. Patients without urinary diversion lead to symptoms such as hematuria and ureteral colic, whereas stones in patients with urinary diversion tend to be asymptomatic and are often diagnosed incidentally during staging examinations of oncologic diseases. We report the case of a 64-year-old male patient with a lower pole kidney stone and a stone in the ileal ureter substitution. He presented with diffuse abdominal and left-sided flank pain...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/28894532/an-ethno-pharmacological-study-of-plants-used-for-traditional-medication-in-tangail-district-bangladesh
#9
A H M Mahmudur Rahman, Mahmoud Rafieian-Kopaei
BACKGROUND: In Bangladesh, folk medicinal practitioners are called "Kaviraj" and are consulted for treatment of various ailments by a large part of the rural and urban population. There are some previous studies conducted in the Tangail district of Bangladesh about medicinal plants, but there is no relevant information about this aspect in some parts of this district. AIM: To conduct an ethno-pharmacological survey among the "Kaviraj" of two upazilas (regions) in Tangail district, namely Tangail Sadar Upazila and Nagarpur Upazila, to identify the trouble-free formulations of medicinal plants for various diseases used by the folk medicine practitioners on or after other forms of medical practices...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28890392/natural-history-and-predictors-of-parastomal-hernia-after-robot-assisted-radical-cystectomy-and-ileal-conduit-urinary-diversion
#10
Ahmed A Hussein, Youssef E Ahmed, Paul May, Taimoor Ali, Basim Ahmad, Sana Raheem, Kevin Stone, Adam Hasasnah, Omer Rana, Adam Cole, Derek Wang, Peter Loud, Khurshid A Guru
INTRODUCTION: We investigated the prevalence, variables associated with parastomal hernia (PSH), and its outcomes of after robot-assisted radical cystectomy (RARC) and ileal conduit (IC) for bladder cancer. METHODS: Retrospective review of RARC at our institution was conducted. PSH was defined as protrusion of abdominal contents through the stoma defect in the abdominal wall on cross sectional imaging. PSH was further described in terms of patient and hernia characteristics, symptoms, management and outcomes...
September 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28887264/toe-pressures-are-superior-to-duplex-parameters-in-predicting-wound-healing-following-toe-and-foot-amputations
#11
Patrick A Stone, Alexis Glomski, Stephanie N Thompson, Elliott Adams
BACKGROUND: No criteria, including pre-amputation vascular diagnostic thresholds, have been established to reliably predict healing versus non-healing following minor lower extremity amputations. Thus, the goal of our study was to identify clinical factors, including non-invasive vascular laboratory measures, associated with wound healing following toe, forefoot, and midfoot amputations. METHODS: We retrospectively examined records of patients receiving elective toe, forefoot, or midfoot amputation at our institution over a 5-year span (2010-2015)...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28883679/the-relationship-between-nephrolithiasis-risk-with-body-fat-measured-by-body-composition-analyzer-in-obese-people
#12
Zohreh Bartani, Behzad Heydarpour, Ahmad Alijani, Masoud Sadeghi
BACKGROUND: Nephrolithiasis (kidney stones) continues to be a major cause of morbidity and healthcare spending that visceral and subcutaneous adipose tissue may associate with kidney stone formation. This study aimed to investigate the relationship between nephrolithiasis with visceral fat scale in obese people in Western Iran for the first time. MATERIALS AND METHODS: In 2017, 103 participants with BMI≥30 kg/m(2) were selected for the present study. The participants were divided into two groups, 52 as case group (having the kidney stone) and 58 as healthy control group (no kidney stone or history of the kidney stone or any other disease)...
June 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28882781/ureteroscopic-urinary-stone-treatment-among-patients-with-renal-anomalies-patient-characteristics-and-treatment-outcomes
#13
Jaap D Legemate, Barbaros Baseskioglu, Jakub Dobruch, Jorge Gutierrez-Aceves, Oscar Negrete, Carlos Rioja Sanz, Muharrem Murat Yildiz, Jean Jmch de la Rosette
OBJECTIVES: To evaluate patients' characteristics, surgical procedure data, and outcomes of URS stone treatment in patients with a horseshoe kidney (HSK), ectopic kidney (EK), and malrotated kidney (MK). METHODS: This study is a sub-analysis of the CROES URS Global Study, which was a prospective multicenter observational study, collecting data on URS stone treatment from consecutive patients over a 1-year period. 114 Centers participated in 32 countries. This analysis acuminated on URS stone treatment in the specified renal anomalies: HSK, EK and MK...
September 4, 2017: Urology
https://www.readbyqxmd.com/read/28882031/a-multiregional-italian-cohort-of-24-hour-urine-metabolic-evaluation-in-renal-stone-formers
#14
Francesco Esperto, Martino Marangella, Alberto Trinchieri, Michele Petrarulo, Roberto Miano
BACKGROUND: Nephrolithiasis is a common condition with several studies documenting an increased prevalence over the past four decades. EAU and AUA guidelines recommend 24-hour urine metabolic evaluation in high-risk stone formers. Aim of this study is to retrospectively evaluate the first three years of experience with Lithotest® (Biohealth Italia Srl, Turin, Italy) through the analysis of demographic, clinical and biochemical data collected from a large cohort of patients with kidney stones...
September 7, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28875258/molecular-analysis-of-oxalate-induced-endoplasmic-reticulum-stress-mediated-apoptosis-in-the-pathogenesis-of-kidney-stone-disease
#15
Albert Abhishek, Shaly Benita, Monika Kumari, Divya Ganesan, Eldho Paul, Ponnusamy Sasikumar, Ayyavu Mahesh, Subramani Yuvaraj, Tharmarajan Ramprasath, Govindan Sadasivam Selvam
Oxalate, a non-essential end product of metabolism, causes hyperoxaluria and eventually calcium oxalate (CaOx) stone disease. Kidney cells exposed to oxalate stress results in generation of reactive oxygen species (ROS) and progression of stone formation. Perturbations in endoplasmic reticulum (ER) result in accumulation of misfolded proteins and Ca(2+) ions homeostasis imbalance and serve as a common pathway for various diseases, including kidney disorders. ER stress induces up-regulation of pro-survival protein glucose-regulated protein 78 (GRP78) and pro-apoptotic signaling protein C/EBP homologous protein (CHOP)...
September 5, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28868511/optimization-of-urinary-dipstick-ph-are-multiple-dipstick-ph-readings-reliably-comparable-to-commercial-24-hour-urinary-ph
#16
Joel E Abbott, Daniel L Miller, William Shi, David Wenzler, Fuad F Elkhoury, Nishant D Patel, Roger L Sur
PURPOSE: Accurate measurement of pH is necessary to guide medical management of nephrolithiasis. Urinary dipsticks offer a convenient method to measure pH, but prior studies have only assessed the accuracy of a single, spot dipstick. Given the known diurnal variation in pH, a single dipstick pH is unlikely to reflect the average daily urinary pH. Our goal was to determine whether multiple dipstick pH readings would be reliably comparable to pH from a 24-hour urine analysis. MATERIALS AND METHODS: Kidney stone patients undergoing a 24-hour urine collection were enrolled and took images of dipsticks from their first 3 voids concurrently with the 24-hour collection...
September 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28868331/mass-spectrometry-based-in-vitro-assay-to-identify-drugs-that-influence-cystine-solubility
#17
Neelanjan Bose, Tiffany Zee, Pankaj Kapahi, Marshall L Stoller
Cystinuria is a rare genetic disorder characterized by recurrent, painful kidney stones, primarily composed of cystine, the dimer of the amino acid cysteine (Sumorok and Goldfarb, 2013). Using a mouse model of cystinuria, we have recently shown that administration of drugs that increase cystine solubility in the urine can be a novel therapeutic strategy for the clinical management of the disease (Zee et al., 2017). There is a large unmet need in the field for developing new drugs for cystinuria. To that end, here we describe a simple in vitro cystine solubility assay that is amenable for screening compounds to identify potential drugs that may influence cystine solubility...
July 20, 2017: Bio-protocol
https://www.readbyqxmd.com/read/28861305/laparoscopic-transperitoneal-and-retroperitoneal-simple-nephrectomy-the-impact-of-etiological-factors-of-the-results-of-surgical-treatment
#18
Rauf Naghiyev, Sudeyf Imamverdiyev, Elchin Efendiyev, Öner Şanlı
OBJECTIVE: This retrospective study compares the perioperative outcomes of laparoscopic simple nephrectomy (LSN) in patients with urinary stone disease (USD) in comparison with LSNs performed for other etiological factors. MATERIAL AND METHODS: 115 LSNs were identified from the two teaching hospitals' database. Depending on the etiological factors, patients were stratified in 2 groups. Group 1 consisted of 63 (mean age 44.8±1.7 [21-71] years) patients; where the cause of non-functioning kidney was USD...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28861302/factors-associated-with-postoperative-pain-after-retrograde-intrarenal-surgery-for-kidney-stones
#19
Ural Oğuz, Tolga Şahin, Çağrı Şenocak, Ekrem Özyuvalı, Ömer Faruk Bozkurt, Berkan Reşorlu, Ali Ünsal
OBJECTIVE: We aimed to investigate factors related to early postoperative pain after retrograde intrarenal surgery (RIRS). MATERIAL AND METHODS: A prospective data analysis of 250 patients who underwent RIRS due to kidney stones was performed. Postoperative pain was evaluated in all patients by using visual analogue scale (VAS). Patients with severe pain (VAS score ≥7) were separated and included in Group I (n=46). While patients without pain or with insignificant pain were included in Group II (n=204)...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28858562/evaluation-of-kidney-stones-with-reduced-radiation-dose-ct-progress-from-2011-2012-to-2015-2016-not-there-yet
#20
Karrin Weisenthal, Priyadarshini Karthik, Melissa Shaw, Debapriya Sengupta, Mythreyi Bhargavan-Chatfield, Judy Burleson, Adel Mustafa, Mannudeep Kalra, Christopher Moore
Purpose To determine if the use of reduced-dose computed tomography (CT) for evaluation of kidney stones increased in 2015-2016 compared with that in 2011-2012, to determine variability in radiation exposure according to facility for this indication, and to establish a current average radiation dose for CT evaluation for kidney stones by querying a national dose registry. Materials and Methods This cross-sectional study was exempt from institutional review board approval. Data were obtained from the American College of Radiology dose registry for CT examinations submitted from July 2015 to June 2016...
August 31, 2017: Radiology
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