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https://www.readbyqxmd.com/read/28732093/attitudes-among-transplant-professionals-regarding-shifting-paradigms-in-eligibility-criteria-for-live-kidney-donation
#1
Jeffrey A Lafranca, Emerentia Q W Spoon, Jacqueline van de Wetering, Jan N M IJzermans, Frank J M F Dor
BACKGROUND: The transplant community increasingly accepts extended criteria live kidney donors, however, great (geographical) differences are present in policies regarding the acceptance of these donors, and guidelines do not offer clarity. The aim of this survey was to reveal these differences and to get an insight in both centre policies as well as personal beliefs of transplant professionals. METHODS: An online survey was sent to 1128 ESOT-members. Questions were included about several extended donor criteria; overweight/obesity, older age, vascular multiplicity, minors as donors and comorbidities; hypertension, impaired fasting glucose, kidney stones, malignancies and renal cysts...
2017: PloS One
https://www.readbyqxmd.com/read/28727384/a-neural-network-based-algorithm-for-predicting-stone-free-status-after-eswl-therapy
#2
Ilker Seckiner, Serap Seckiner, Haluk Sen, Omer Bayrak, Kazim Dogan, Sakip Erturhan
OBJECTIVE: The prototype artificial neural network (ANN) model was developed using data from patients with renal stone, in order to predict stone-free status and to help in planning treatment with Extracorporeal Shock Wave Lithotripsy (ESWL) for kidney stones. MATERIALS AND METHODS: Data were collected from the 203 patients including gender, single or multiple nature of the stone, location of the stone, infundibulopelvic angle primary or secondary nature of the stone, status of hydronephrosis, stone size after ESWL, age, size, skin to stone distance, stone density and creatinine, for eleven variables...
July 20, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28727383/outcomes-of-miniaturized-percutaneous-nephrolitotomy-in-infants-single-centre-experience
#3
Eyyup Sabri Pelit, Bülent Kati, Cengiz Çanakci, Süleyman Sağir, Halil Çiftçi
OBJECTIVES: The present study was aim to evaluate the safety and efficacy of Mini-PNL to treat kidney stones in patients aged <3 years. This is the one of the largest series in the literature in this age group of patients. MATERIAL AND METHODS: From May 2012 to April 2016, the medical records of 74 infant patients who underwent mini-PNL for renal stones were reviewed retrospectively. All infants were evaluated with the plain abdominal radiograph, urinary ultrasound, noncontrast computerized tomography and/or intravenous urogram...
July 20, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28726586/application-of-ureterorenoscope-and-flexible-ureterorenoscope-lithotripsy-in-removing-calculus-from-extracorporeal-living-donor-renal-graft-a-single-center-experience
#4
Chun-Hua Lin, Zuo-Fu Zhang, Jiahui Wang, Lu-Xin Yu, Wen-Ting Wang, Lei Shi, Xiang-Nan Lin
Here, we reported our clinical application of ureterorenoscope (URS) and flexible URS lithotripsy in stone removal on 10 cases of excised living donor kidney graft. After the extraction of donor kidney by retroperitoneal laparoscopy, the donor graft was perfused with 4 °C HCA solution. Calculus between 2-4 mm were removed intact with lithotomy forceps under direct vision of URS. Larger calculi of >4 mm were fractured with flexible URS combining holmium laser lithotripsy. Fragments of the calculus were extracted with basket extractor and lithotomy forceps...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28723379/minilaparoendoscopic-single-site-pyeloplasty-the-best-compromise-between-surgeon-s-ergonomy-and-patient-s-cosmesis-ideal-phase-2a
#5
Francesco Greco, Giovannalberto Pini, Stefano Alba, Vincenzo Maria Altieri, Paolo Verze, Vincenzo Mirone
BACKGROUND: Laparoendoscopic single-site (LESS) surgery and minilaparoscopy (ML) represent the evolution of laparoscopy for the treatment of urologic diseases. OBJECTIVE: To describe the technique and report the surgical outcomes of minilaparoendoscopic single-site dismembered pyeloplasty (MILESS-DP), a new technique overcoming the technical limitations of LESS and ML, and equally combining the advantages of both these surgical procedures. DESIGN, SETTING, AND PARTICIPANTS: Twenty consecutive patients underwent MILESS-DP for ureteropelvic junction obstruction...
August 2016: European Urology Focus
https://www.readbyqxmd.com/read/28721286/open-stone-surgery-a-still-in-use-approach-for-complex-stone-burden
#6
Özer Ural Çakici, Kemal Ener, Murat Keske, Serkan Altinova, Abdullah Erdem Canda, Mustafa Aldemir, Arslan Ardicoglu
INTRODUCTION: Urinary stone disease is a major urological condition. Endourologic techniques have influenced the clinical approach and outcomes. Open surgery holds a historic importance in the management of most conditions. However, complex kidney stone burden may be amenable to successful results with open stone surgery. In this article, we report our eighteen cases of complex urinary stone disease who underwent open stone removal. MATERIAL AND METHODS: A total of 1701 patients have undergone surgical treatment for urinary stone disease in our clinic between July 2012 and July 2016, comprising eighteen patients who underwent open stone surgery...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28721285/ureteroscopy-for-stone-disease-expanding-roles-in-the-modern-era
#7
REVIEW
Adrian Ho, Piyush Sarmah, Ewa Bres-Niewada, Bhaskar K Somani
INTRODUCTION: The prevalence of urolithiasis is increasing worldwide and is causing significant morbidity and cost to the healthcare systems. While ureteroscopy (URS) has been established as a treatment option, our review highlights the expanding role of URS for the management of more complex stones and patients in the modern era. MATERIAL AND METHODS: Ureteroscopy has shown to have good outcomes with stone free rates (SFR) comparable to other treatment modalities...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28720371/genetic-risk-factors-for-idiopathic-urolithiasis-a-systematic-review-of-the-literature-and-causal-network-analysis
#8
REVIEW
Kazumi Taguchi, Takahiro Yasui, Dawn Schmautz Milliner, Bernd Hoppe, Thomas Chi
CONTEXT: Urolithiasis has a high prevalence and recurrence rate. Prevention is key to patient management, but risk stratification is challenging. In particular, genetic predisposition for urinary stones is not fully understood. OBJECTIVE: To review current evidence of potential causative genes for idiopathic urolithiasis and map their relationships to one another. This evidence is essential for future establishment of molecular targeted therapy. EVIDENCE ACQUISITION: A systematic literature review from 2007 to 2017 was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720370/the-swiss-kidney-stone-cohort-an-observational-study-to-unravel-the-cause-of-renal-stone-formation
#9
Beat Roth, Olivier Bonny
Its nationwide character, standardized and extensive patient work-up, long-term follow-up, and significant number of patients recruited make the Swiss Kidney Stone Cohort a valuable tool to better understand the pathophysiology of kidney stone formation.
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720366/the-evolving-role-of-retrograde-intrarenal-surgery-in-the-treatment-of-urolithiasis
#10
REVIEW
Francesco Sanguedolce, Giorgio Bozzini, Ben Chew, Panagiotis Kallidonis, Jean de la Rosette
CONTEXT: Retrograde intrarenal surgery has gained substantial popularity worldwide thanks to continuous improvements in technology and techniques, and is now considered one of the first-line treatment options for active removal of renal stones. OBJECTIVE: To provide a comprehensive synthesis of the main evidences in literature on the current management of kidney stones by means of retrograde intrarenal surgery (RIRS). EVIDENCE ACQUISITION: A review of literature has been conducted using search string "retrograde intrarenal surgery OR flexible ureteroscop* OR ureterorenoscop*", without any language restriction; PubMed, Embase, and Scopus databases were searched in November 2016...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720362/case-discussion-kidney-stone-in-a-patient-with-an-ileal-conduit
#11
Cesare Marco Scoffone, Cecilia Maria Cracco
Kidney stones in patients with ileal conduit and multiple sclerosis are secondary to postoperative anatomical changes and ascending urinary tract infections by urea-splitting bacteria. PNL is the preferred treatment option in patients with urinary diversion and infectious renal stones.
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720360/kidney-stone-in-a-patient-with-an-ileal-conduit
#12
Steeve Doizi, Olivier Traxer
The advantage of a retrograde over an antegrade approach in ileal conduit diversion is the lower morbidity. Furthermore, in cases in which there are bone deformities and no ureteral reflux from the reservoir into the upper tract, percutaneous access can be challenging. Thus, a retrograde approach should be considered as the first-line option for the treatment of renal stones in patients with an ileal conduit, but the urologist should keep in mind that an antegrade or combined approach may be possible in the case of failure...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720357/clinical-case-discussion-kidney-stone-in-a-patient-with-an-ileal-conduit
#13
R Jeroen A van Moorselaar, Jakko A Nieuwenhuijzen
A patient underwent robot-assisted laparoscopic cystectomy with an ileal conduit urinary diversion. Percutaneous nephrolithotomy was performed for treatment of a kidney stone. Stone analysis revealed struvite.
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720352/medical-measures-for-secondary-prevention-of-urolithiasis
#14
Khashayar Sakhaee
The global prevalence of nephrolithiasis has progressively increased over the past several decades. Kidney stone disease without treatment is a recurrent illness that represents a major health burden across the globe with associated economic costs.
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28719978/optimizing-rna-extraction-of-renal-papilla-biopsy-tissue-in-kidney-stone-formers-a-new-methodology-for-genomic-study
#15
Kazumi Taguchi, Manint Usawachintachit, Shuzo Hamamoto, Rei Unno, David T Tzou, Benjamin Sherer, Yongmei Wang, Atsushi Okada, Marshall Stoller, Takahiro Yasui, Thomas Chi
INTRODUCTION: Endoscopic tools have provided versatile examination and treatment for kidney stone procedures. Despite endourologists researching urinary stone disease using endoscopes to collect tissue, this tissue collection method is limited. Endoscopically removed tissues are small in size, restricting the types of genome-based examination possible. We investigated a new method of renal papilla biopsy and RNA extraction to establish a genomic research methodology for kidney stone disease...
July 18, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28718073/a-randomised-phase-ii-iii-study-to-evaluate-the-efficacy-and-safety-of-orally-administered-oxalobacter-formigenes-to-treat-primary-hyperoxaluria
#16
Dawn Milliner, Bernd Hoppe, Jaap Groothoff
Primary hyperoxaluria (PH) patients overproduce oxalate because of rare genetic errors in glyoxylate metabolism. Recurrent urolithiasis and/or progressive nephrocalcinosis are PH hallmarks and can lead to kidney damage, systemic oxalosis and death. Based on previous studies, we hypothesised that treatment with the oxalate-metabolizing bacterium Oxalobacter formigenes would mediate active elimination of oxalate from the plasma to the intestine of PH patients, thereby reducing urinary oxalate excretion (Uox)...
July 17, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28716570/protective-effects-of-pistacia-lentiscus-l-fruit-extract-against-calcium-oxalate-monohydrate-induced-proximal-tubular-injury
#17
Nassima Cheraft-Bahloul, Cécile Husson, Meriam Ourtioualous, Sébastien Sinaeve, Djebbar Atmani, Caroline Stévigny, Joëlle L Nortier, Marie-Hélène Antoine
ETHNOPHARMACOLOGICAL RELEVANCE: The world prevalence of kidney stones is increasing and plants are frequently used to treat urolithiasis. Pistacia lentiscus L, a plant which freely grows around the Mediterranean basin areas, is widely used for various pathologies. P. lentiscus has an important impact as it has economical value on top of its pharmacological interest. Decoctions of its aerial parts and/or resin are used to treat kidney stones. AIM OF THE STUDY: To in vitro assess the potential nephroprotective effect of Pistacia lentiscus ethanolic fruit extract (PLEF) on proximal tubular cells in response to the adhesion of calcium oxalate monohydrate (COM) crystals...
July 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28711370/assessing-the-risk-of-hypercalcemic-crisis-in-patients-with-primary-hyperparathyroidism
#18
Andrew J Lowell, Norah M Bushman, Xing Wang, Yue Ma, Susan C Pitt, Rebecca S Sippel, David F Schneider, Reese W Randle
BACKGROUND: Hypercalcemic crisis (HC) is a potentially life-threatening manifestation of primary hyperparathyroidism (PHPT). This study aimed to identify patients with PHPT at greatest risk for developing HC. METHODS: This retrospective cohort study included patients with a preoperative calcium of at least 12 mg/dL undergoing initial parathyroidectomy for PHPT from 11/2000 to 03/2016. We compared those with HC, defined as needing hospitalization for hypercalcemia, to those without HC...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28705966/genome-sequence-of-oxalobacter-formigenes-strain-oxcc13
#19
Marguerite Hatch, Milton J Allison, Fahong Yu, William Farmerie
The lack of Oxalobacter formigenes colonization in the human gut is generally acknowledged as a risk factor for kidney stone formation since this microorganism can play an important role in oxalate homeostasis. Here, we present the genome sequence of OXCC13, a human strain isolated from an individual residing in Germany.
July 13, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28704268/safe-discharge-and-outpatient-investigation-of-ureteric-colic-a-retrospective-analysis
#20
Michael Stewart
BACKGROUND: Computed tomography of the kidneys, ureters and bladder is the recommended imaging modality for suspected urolithiasis. Early scanning is advised in guidelines, but there is limited published evidence to support this recommendation. PATIENTS AND METHODS: In a retrospective study, we reviewed patients managed according to a local guideline. Patients without high-risk features were either imaged during their initial visit (if in the daytime) or discharged for outpatient scans...
July 12, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
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