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Preconception health

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https://www.readbyqxmd.com/read/29163369/preconception-prebiotic-and-sitagliptin-treatment-in-obese-rats-affects-pregnancy-outcomes-and-offspring-microbiota-adiposity-and-glycemia
#1
Carol A Dennison, Amanda J Eslinger, Raylene A Reimer
Maternal obesity is associated with increased risk of pregnancy complications and greater risk of obesity in offspring, but studies designed to examine preconception weight loss are limited. The objective of this study was to determine if a combined dietary [oligofructose (OFS)] and pharmacological (sitagliptin) preconception intervention could mitigate poor pregnancy outcomes associated with maternal obesity and improve offspring metabolic health and gut microbiota composition. Diet-induced obese female Sprague-Dawley rats were randomized to one of four intervention groups for 8 weeks: (1) Obese-Control (consumed control diet during intervention); (2) Obese-OFS (10% OFS diet); (3) Obese-S (sitagliptin drug); (4) Obese-OFS + S (combination treatment)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29162676/the-role-of-genetic-counseling-in-pompe-disease-after-patients-are-identified-through-newborn-screening
#2
Andrea M Atherton, Debra Day-Salvatore
An important part of the coordinated care by experienced health care teams for all Pompe disease patients, whether diagnosed through newborn screening (NBS), clinical diagnosis, or prenatal diagnosis, is genetic counseling. Genetic counseling helps families better understand medical recommendations and options presented by the patient's health care team so they can make informed decisions. In addition to providing important information about the inheritance and genetic risks, genetic counseling also provides information about Pompe disease and available treatments and resources and should be offered to families with an affected child and all adults diagnosed with Pompe disease...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/29138159/preconception-health-care-tool-one-stop-shop-for-preconception-care
#3
Deanna Telner, Rebekah Barrett, Apurva Shirodkar, Amanda van Hal, Lena Salach
No abstract text is available yet for this article.
November 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29128989/infant-mortality-lessons-learned-from-a-fetal-and-infant-mortality-review-program
#4
Haywood L Brown, Mark Smith, Yvonne Beasley, Teri Conard, Anne Lise Musselman, Virginia A Caine
Objective To review fetal and infant deaths from women enrolled in Indianapolis Healthy Start using the National Fetal and Infant Mortality Review (FIMR) methods to provide strategies for prevention. METHODS: Marion County Public Health Department (MCPHD) FIMR staff identified and reviewed 22 fetal and infant deaths to Indianapolis Healthy Start program participants between 2005 and 2012. Trained FIMR nurses completed 13 of 20 maternal interviews and compiled case summaries of all deaths from the MCPHD FIMR database...
November 11, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29127865/which-information-on-women-s-issues-in-epilepsy-does-a-community-pharmacist-need-to-know-a-delphi-consensus-study
#5
Ramzi Shawahna
OBJECTIVE: The aim of this study was to develop and achieve consensus on a core list of important knowledge items that community pharmacists should know on women's issues in epilepsy. METHODS: This was a consensual study using a modified Delphi technique. Knowledge items were collected from the literature and from nine key contacts who were interviewed on their views on what information community pharmacists should have on women's issues in epilepsy. More knowledge items were suggested by five researchers with interest in women's issues who were contacted to rate and comment on the knowledge items collected...
November 8, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29122094/periconceptional-folic-acid-supplementation-in-chinese-women-a-cross-sectional-study
#6
Jing Yan, Yu Zhi Zheng, Lu Jia Cao, Yu Yan Liu, Wen Li, Guo Wei Huang
OBJECTIVE: To investigate the status of folic acid (FA) supplementation and determinants of its use in pregnant Chinese women. METHODS: In this cross-sectional study, questionnaires were used to collect information of participants and FA supplementation. Women were recruited between 6 and 12 weeks postpartum in Tianjin, China, between July 2015 and July 2016. RESULTS: A total of 1,921 women were recruited in the study. Approximately 93.1% of the study participants used FA, while 14...
October 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/29121445/viraemia-before-during-and-after-pregnancy-in-hiv-infected-women-on-antiretroviral-therapy-in-rural-kwazulu-natal-south-africa-2010-2015
#7
Terusha Chetty, Marie-Louise Newell, Claire Thorne, Anna Coutsoudis
OBJECTIVES: Pregnancy and postpartum viral load suppression is critical to prevent mother-to-child HIV transmission and ensure maternal health. We measured viraemia risk before, during and after pregnancy in HIV-infected women. METHODS: Between 2010 and 2015, 1425 HIV-infected pregnant women on lifelong antiretroviral therapy (ART) for at least six months pre-pregnancy were enrolled in a cohort study in rural KwaZulu-Natal, South Africa. Odds ratios were estimated in multilevel logistic regression, with pregnancy period time varying...
November 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29120703/maternal-obesity-gestational-weight-gain-and-asthma-in-offspring
#8
Kristen J Polinski, Jihong Liu, Nansi S Boghossian, Alexander C McLain
INTRODUCTION: Obesity is common among women of childbearing age; intrauterine exposure to maternal obesity or gestational weight gain may influence the development of asthma in early childhood. We examined the relationships of maternal obesity and gestational weight gain with asthma in offspring. METHODS: We used data from the Early Childhood Longitudinal Study-Birth Cohort, which has a nationally representative sample of children followed from birth in 2001 through age 4 (n = 6,450)...
November 9, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29120310/preconception-health-interventions-delivered-in-public-health-and-community-settings-a-systematic-review
#9
Hilary K Brown, Melissa Mueller, Sarah Edwards, Catriona Mill, Joanne Enders, Lisa Graves, Deanna Telner, Cindy-Lee Dennis
OBJECTIVES: The objective of this systematic review was to assess the effects of preconception health interventions, delivered to individuals of reproductive age in public health and community settings, on reproductive, maternal, and child health outcomes. METHODS: A search of Ovid MEDLINE, CINAHL, EMBASE, PsychINFO, Scopus, Gender Studies Database, and SocINDEX from July 1999 through July 2016 was performed. We included studies that reported original data, used an interventional study design, included reproductive-aged women or men, were written in English, and were published in peer-reviewed journals...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29117460/maternal-folic-acid-use-during-pregnancy-mthfr-polymorphism-and-child-s-lung-function-and-asthma
#10
Herman T den Dekker, Vincent W V Jaddoe, Irwin K Reiss, Johan C de Jongste, Liesbeth Duijts
BACKGROUND: Folic acid supplement use during pregnancy might affect childhood respiratory health, potentially mediated by methylenetetrahydrofolate-reductase polymorphism C677T (MTHFR-C677T) carriership. OBJECTIVES: We examined the associations of maternal folic acid supplement use and folate, vitamin B12 and homocysteine concentrations during pregnancy with childhood lung function and asthma. METHODS: This study was embedded in a population-based prospective cohort study among 5,653 children...
November 8, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29116583/innovative-clinical-pathways-for-obese-pregnant-women-design-and-feasibility-of-the-padua-project-north-eastern-italy
#11
A Lapolla, D Scibetta, P Gallina, G Iorizzo, M G Dalfrà, S Visentin, G B Nardelli, R Vettor
BACKGROUND: Obesity during pregnancy can adversely affect the wellbeing of the mother and the newborn, as well as the latter's long-term health. Preconception counseling, careful prenatal management, and strict follow-up during pregnancy are, therefore, essential for obese fertile women in order to prevent the negative effects of obesity. METHODS: In this setting, we developed a project that consisted in creating an integrated network of primary, secondary, and tertiary care providers and designing new clinical pathways for managing pregnancy in obese women...
November 7, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29114556/the-prevalence-of-preconception-care-its-relation-with-recipients-individuality-fertility-and-the-causes-of-lack-of-checkup-in-women-who-gave-birth-in-isfahan-hospitals-in-2016
#12
Parisa Shadab, Nafisehsadat Nekuei, Ghasem Yadegarfar
BACKGROUND: Preconception care is a set of interventions that aim to identify and repair the factors that can affect the outcome of pregnancy. The aim of this study was to determine the prevalence of receiving preconception care, its relation with recipients' individuality, fertility, and determining the reason for lack of checkup. MATERIALS AND METHODS: This was a descriptive cross-sectional study that was conducted based on simple stratified random quota sampling on 702 women who gave birth in hospitals of Isfahan (Iran) from April to June in 2016...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29102040/preconceptional-antithyroid-peroxidase-antibodies-but-not-thyroid-stimulating-hormone-are-associated-with-decreased-live-birth-rates-in-infertile-women
#13
Aimee Seungdamrong, Anne Z Steiner, Clarisa R Gracia, Richard S Legro, Michael P Diamond, Christos Coutifaris, William D Schlaff, Peter Casson, Gregory M Christman, Randal D Robinson, Hao Huang, Ruben Alvero, Karl R Hansen, Susan Jin, Esther Eisenberg, Heping Zhang, Nanette Santoro
OBJECTIVE: To study whether preconceptual thyroid-stimulating hormone (TSH) and antithyroid peroxidase (TPO) antibodies are associated with poor reproductive outcomes in infertile women. DESIGN: Secondary analysis of data from two multicenter, randomized, controlled trials conducted by the Reproductive Medicine Network of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Multivariable logistic regression analyses were performed to assess the association between preconceptual TSH levels and anti-TPO antibodies...
October 25, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29096774/thinking-across-generations-unique-contributions-of-maternal-early-life-and-prenatal-stress-to-infant-physiology
#14
Sarah A O Gray, Christopher W Jones, Katherine P Theall, Erin Glackin, Stacy S Drury
OBJECTIVE: Respiratory sinus arrhythmia (RSA) is a parasympathetic-mediated biomarker of self-regulation linked to lifespan mental and physical health outcomes. Intergenerational impacts of mothers' exposure to prenatal stress have been demonstrated, but evidence for biological embedding of maternal preconception stress, including adverse childhood experiences (ACEs), on infant RSA is lacking. We examine the independent effects of maternal ACEs and prenatal stress on infant RSA, seeking to broaden the understanding of the earliest origins of mental and physical health risk...
November 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29096279/preconception-lifestyle-changes-in-women-with-planned-pregnancies
#15
Joline Goossens, Dimitri Beeckman, Ann Van Hecke, Ilse Delbaere, Sofie Verhaeghe
OBJECTIVES: (1) to study preconception lifestyle changes and associated factors in women with planned pregnancies; (2) to assess the prevalence of risk factors for adverse pregnancy outcomes in women not reporting any preconception lifestyle changes; and (3) to explore the need for and use of preconception-related advice. DESIGN: secondary data analysis of a cross-sectional study about pregnancy planning. SETTING: six Flemish Hospitals (Belgium)...
October 24, 2017: Midwifery
https://www.readbyqxmd.com/read/29094755/unplanned-pregnancies-in-new-zealand
#16
Bryndl E Hohmann-Marriott
BACKGROUND: Unplanned pregnancies can bring risk. It is important to have an accurate count of unplanned pregnancies, but to date there is no precise number for New Zealand or Australia. AIMS: This analysis estimates the number and proportion of pregnancies in New Zealand that are unplanned. MATERIALS AND METHODS: Estimates were generated using information about unplanned births from the Growing Up in New Zealand study, combined with data on the number of births and abortions from Statistics New Zealand and estimates of miscarriages...
November 2, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29089177/trajectories-of-maternal-leisure-time-physical-activity-and-sedentary-behavior-during-adolescence-to-young-adulthood-and-offspring-birthweight
#17
Sylvia E Badon, Alyson J Littman, Kwun Chuen Gary Chan, Michelle A Williams, Daniel A Enquobahrie
PURPOSE: The objectives of the study were to determine the extent to which trajectories of maternal preconception leisure-time physical activity (LTPA) and leisure-time sedentary behavior (LTSB) during adolescence and young adulthood are associated with offspring birth weight (BW) and to test if these associations differ by offspring sex or maternal pre-pregnancy overweight-obese status. METHODS: Participants with one or more birth (n = 1408) were identified from the National Longitudinal Study of Adolescent to Adult Health...
October 13, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29084307/association-between-pesticide-residue-intake-from-consumption-of-fruits-and-vegetables-and-pregnancy-outcomes-among-women-undergoing-infertility-treatment-with-assisted-reproductive-technology
#18
Yu-Han Chiu, Paige L Williams, Matthew W Gillman, Audrey J Gaskins, Lidia Mínguez-Alarcón, Irene Souter, Thomas L Toth, Jennifer B Ford, Russ Hauser, Jorge E Chavarro
Importance: Animal experiments suggest that ingestion of pesticide mixtures at environmentally relevant concentrations decreases the number of live-born offspring. Whether the same is true in humans is unknown. Objective: To examine the association of preconception intake of pesticide residues in fruits and vegetables (FVs) with outcomes of infertility treatment with assisted reproductive technologies (ART). Design, Setting, and Participants: This analysis included 325 women who completed a diet assessment and subsequently underwent 541 ART cycles in the Environment and Reproductive Health (EARTH) prospective cohort study (2007-2016) at a fertility center at a teaching hospital...
October 30, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29080126/perinatal-periods-of-risk-analysis-disentangling-race-and-socioeconomic-status-to-inform-a-black-infant-mortality-community-action-initiative
#19
Catherine L Kothari, Camryn Romph, Terra Bautista, Debra Lenz
Objectives The goal of this study is to use Perinatal Periods of Risk (PPOR) analysis to differentiate broad areas of risk (Maternal-Health/Prematurity, Maternal Care, Newborn Care, and Infant Health) associated with being Black from those associated with being poor. Methods Phase I PPOR compared two target populations (Black women/infants and poor women/infants) against a gold standard reference group (White, non-Hispanic women, aged 20+ years with 13+ years of education), then against each other. Phase II PPOR further partitioned excess risk into (1) Very-low-birthweight-risk and (2) Birthweight-specific-mortality-risk and identified individual-level risk factors...
October 27, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29073916/participant-recruitment-and-retention-in-longitudinal-preconception-randomized-trials-lessons-learnt-from-the-calcium-and-pre-eclampsia-cap-trial
#20
Theresa A Lawrie, Ana Pilar Betrán, Mandisa Singata-Madliki, Alvaro Ciganda, G Justus Hofmeyr, José M Belizán, Tina Dannemann Purnat, Sarah Manyame, Catherine Parker, Gabriela Cormick
BACKGROUND: The preconception period has the potential to influence pregnancy outcomes and randomized controlled trials (RCTs) are needed to evaluate a variety of potentially beneficial preconception interventions. However, RCTs commencing before pregnancy have significant participant recruitment and retention challenges. The Calcium And Pre-eclampsia trial (CAP trial) is a World Health Organization multi-country RCT of calcium supplementation commenced before pregnancy to prevent recurrent pre-eclampsia in which non-pregnant participants are recruited and followed up until childbirth...
October 26, 2017: Trials
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