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Preconception health

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https://www.readbyqxmd.com/read/28911790/microchimerism-defining-and-redefining-the-prepregnancy-context-a-review
#1
H S Gammill, W E Harrington
Bidirectional transplacental exchange characterizes human pregnancy. Cells exchanged between mother and fetus can durably persist as microchimerism and may have both short- and long-term consequences for the recipient. The amount, type, and persistence of microchimerism are influenced by obstetric characteristics, pregnancy complications, exposures to infection, and other factors. A reproductive-aged woman enters pregnancy harboring previously acquired microchimeric "grafts," which may influence her preconception health and her subsequent pregnancy outcomes...
August 31, 2017: Placenta
https://www.readbyqxmd.com/read/28895680/optimising-preconception-health-in-women-of-reproductive-age
#2
Adina Y Lang, Jacqueline A Boyle, Grace Fitzgerald, Helena Teede, Danielle Mazza, Lisa J Moran, Cheryce Harrison
There is a growing realisation that efforts to optimise the health of women and reduce the risk of adverse maternal, perinatal and neonatal outcomes during pregnancy should commence in the preconception period. The preconception period (prior to or between pregnancies) provides an opportune time to address reproductive intentions and promote and support wellbeing and healthy behaviour change regardless of pregnancy intention. Research over the last 30 years has explored the influence of a range of preconception risk factors and determinants of health on pregnancy and maternal and neonatal outcomes including: pregnancy planning, diet and micronutrient supplementation, physical activity, weight, smoking, recreational drug and alcohol use, mental health, oral hygiene, and chronic health and medical conditions...
September 12, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28888348/nursing-across-the-lifespan-implications-of-lifecourse-theory-for-nursing-research
#3
Randi A Bates, Lisa M Blair, Emma C Schlegel, Colleen M McGovern, Marliese Dion Nist, Stephanie Sealschott, Kimberly Arcoleo
Despite the lifecourse focus of nursing clinical care, nursing research largely remains cross-sectional or process-oriented within silos determined by patient characteristics such as age, acuity, or disease process. Incorporating interdisciplinary lifecourse theory into pediatric nursing research provides the opportunity to expand nursing theories and research beyond practice, age, and disease silos. One such theory is the Lifecourse Health Development (LCHD) framework. LCHD takes a more expansive view of health development from preconception through old age based on the premise that health is a consequence of transactions between genetic, biological, behavioral, social, and economic contexts that change as a child develops over time (Halfon & Hochstein, 2002)...
September 7, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28882122/prevalence-and-predictors-of-early-gestational-weight-gain-associated-with-obesity-risk-in-a-diverse-australian-antenatal-population-a-cross-sectional-study
#4
K Cheney, S Berkemeier, K A Sim, A Gordon, K Black
BACKGROUND: Excess gestational weight gain (GWG) leads to adverse short- and long-term consequences for women and their offspring. Evidence suggests that excess GWG in early pregnancy may be particularly detrimental, contributing to the intergenerational cycle of obesity. The primary outcome was to investigate the prevalence and predictors of excess GWG in early pregnancy, and if women understand the risks to themselves and their offspring stratified by maternal body mass index (BMI)...
September 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28881390/prenatal-alcohol-exposure-in-relation-to-autism-spectrum-disorder-findings-from-the-study-to-explore-early-development-seed
#5
Alison B Singer, Arthur S Aylsworth, Christina Cordero, Lisa A Croen, Carolyn DiGuiseppi, M Daniele Fallin, Amy H Herring, Stephen R Hooper, Rebecca E Pretzel, Laura A Schieve, Gayle C Windham, Julie L Daniels
BACKGROUND: Prenatal alcohol exposure can affect neurodevelopment, but few studies have examined associations with autism spectrum disorder (ASD). METHODS: We assessed the association between maternal alcohol use and ASD in the Study to Explore Early Development, a multi-site case-control study of children born between September 2003 and August 2006 in the US Regression analyses included 684 children with research clinician-confirmed ASD, 869 children with non-ASD developmental delays or disorders (DDs), and 962 controls ascertained from the general population (POP)...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28875956/seroepidemiology-of-syphilis-infection-among-2-million-reproductive-age-women-in-rural-china-a-population-based-cross-sectional-study
#6
Kai-Ju Liao, Shi-Kun Zhang, Min Liu, Qiao-Mei Wang, Jue Liu, Hai-Ping Shen, Yi-Ping Zhang
Background: Quantifying syphilis prevalence is important for planning interventions and advocating for resources on syphilis. However, data on large sample studies regarding the prevalence of syphilis among reproductive-age women in rural China were not available for analysis. The aim of the study was to determine the prevalence, epidemiological characteristics, and related factors of syphilis infection among reproductive-age women in rural China. Methods: Data were obtained from a nationwide, population-based, cross-sectional study under the National Free Preconception Health Examination Project which covered all the 31 provinces in Mainland China...
September 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28874178/relationship-between-self-efficacy-and-patient-knowledge-on-adherence-to-oral-contraceptives-using-the-morisky-medication-adherence-scale-mmas-8
#7
Daniel Tomaszewski, Benjamin D Aronson, Margarette Kading, Donald Morisky
BACKGROUND: Preconception care, including family planning, is a vital component of healthcare for women of reproductive age. An average female spends the majority of her reproductive life trying to prevent a pregnancy. In order to prevent unintended pregnancy, women often rely on the use of hormonal contraceptives. In the United States, the majority of hormonal contraceptive users are prescribed oral contraceptive pills (OCPs). Reduced adherence to OCPs decreases their ability to prevent pregnancy...
September 6, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28869206/serum-magnesium-and-calcium-levels-in-infertile-women-during-a-cycle-of-reproductive-assistance
#8
Elena Grossi, Sara Castiglioni, Claudia Moscheni, Patrizio Antonazzo, Irene Cetin, Valeria Maria Savasi
Magnesium (Mg) and calcium (Ca) are essential cations for women's preconception health. It is well known that, in blood, the concentration of ionized form of these two cations is temporally altered during menstrual cycle, suggesting a correlation between sex steroid hormones and serum calcium and magnesium levels. Evidence from literature suggests that in assisted reproductive technology increasing estrogens during ovarian hyperstimulation may also modulate serum magnesium and calcium levels. Therefore, we first examined total serum magnesium and calcium levels during follicular phase in a large population of infertile patients who underwent intrauterine insemination (IUI)...
May 1, 2017: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/28855739/noncoding-rnas-in-neurodegeneration
#9
REVIEW
Evgenia Salta, Bart De Strooper
The emerging complexity of the transcriptional landscape poses great challenges to our conventional preconceptions of how the genome regulates brain function and dysfunction. Non-protein-coding RNAs (ncRNAs) confer a high level of intricate and dynamic regulation of various molecular processes in the CNS and they have been implicated in neurodevelopment and brain ageing, as well as in synapse function and cognitive performance, in both health and disease. ncRNA-mediated processes may be involved in various aspects of the pathogenesis of neurodegenerative disorders...
October 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28854715/systematic-review-and-meta-analysis-of-the-impact-of-preconception-lifestyle-interventions-on-fertility-obstetric-fetal-anthropometric-and-metabolic-outcomes-in-men-and-women
#10
L Lan, C L Harrison, M Misso, B Hill, H J Teede, B W Mol, L J Moran
STUDY QUESTION: What is the impact of preconception lifestyle interventions on live birth, birth weight and pregnancy rate? SUMMARY ANSWER: Lifestyle interventions showed benefits for weight loss and increased natural pregnancy rate, but not for live birth or birth weight. WHAT IS KNOWN ALREADY: Evidence on the practice and content of preconception counseling and interventions is variable and limited. STUDY DESIGN, SIZE, DURATION: Systematic review and meta-analysis (MA)...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28844800/paternal-use-of-azathioprine-6-mercaptopurine-or-methotrexate-within-3-months-before-conception-and-long-term-health-outcomes-in-the-offspring-a-nationwide-cohort-study
#11
S Friedman, M D Larsen, B Magnussen, L R Jølving, P de Silva, B M Nørgård
PURPOSE: We examined the effect of preconception paternal use of azathioprine (AZA)/6-mercaptopurine (6-MP) or methotrexate (MTX) and the risk of adverse long-term outcomes in the offspring. METHODS: This study included all children born in Denmark from 1 January 1997 through 2013. Exposed cohort: children fathered by men who used AZA/6-MP (N=735) or MTX (N=209) within three months before conception; unexposed cohort: children fathered by men who did not use AZA/6-MP/MTX (N=1,056,524)...
August 24, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28835244/improving-preconception-health-and-care-a-situation-analysis
#12
Ashley Goodfellow, John Frank, John McAteer, Jean Rankin
BACKGROUND: The purpose of this situation analysis was to explore the views of health and non-health professionals working with women of childbearing age on current and future delivery of preconception care in one National Health Service (NHS) Board area in Scotland. METHODS: The situation analysis was undertaken using a mixed methods approach. Six focus groups were conducted organised by profession - general practitioners (GPs), practice nurses, health visitors, family nurses, guidance teachers and youth workers...
August 23, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28828743/pregnancy-in-women-with-congenital-heart-disease
#13
REVIEW
Evin Yucel, Doreen DeFaria Yeh
Advances in cardiac surgical interventions in infancy and childhood have led to an increased number of women with congenital heart disease of childbearing age. For these women, individualized preconception counseling and pregnancy planning should be a vital component of their medical management, and presentation for obstetric care may even be an opportunity to re-establish cardiovascular care for patients who have been lost to follow-up. These patients have unique cardiovascular anatomy and physiology, which is dependent upon the surgical intervention they may have undergone during childhood or adolescence...
August 22, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28827230/correlation-between-preconception-maternal-non-occupational-exposure-to-interior-decoration-or-oil-paint-odour-and-average-birth-weight-of-neonates-findings-from-a-nationwide-cohort-study-in-china-s-rural-areas
#14
Huiting Liu, Shi Chen, Huijuan Zhu, Hongbo Yang, Fengying Gong, Linjie Wang, Yu Jiang, Bill Q Lian, Chengsheng Yan, Jianqang Li, Qing Wang, Shikun Zhang, Hui Pan
BACKGROUND: Birth weight is a critical indicator of neonatal health and foretells people's health in adolescence and even adulthood. Some researchers have warned against the adverse effects on babies' birth weight of exposure to pollutants in interior decoration or oil paint by odour intake. This study evaluated the effects of maternal exposure to such factors before conception on the birth weights of neonates. METHODS: Data on 213 461 cases in this study were from the database of the free National Pre-pregnancy Checkups Project...
August 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28818820/opportunities-of-mhealth-in-preconception-care-preferences-and-experiences-of-patients-and-health-care-providers-and-other-involved-professionals
#15
Matthijs R Van Dijk, Maria Ph Koster, Ageeth N Rosman, Regine Pm Steegers-Theunissen
BACKGROUND: The importance of the preconception period and preconception care (PCC) are broadly acknowledged and the potential benefits regarding health promotion have been studied extensively. PCC provides the opportunity to identify, prevent, and treat modifiable and nonmodifiable risk factors to optimize the health of couples trying to become pregnant. The prevalence of modifiable and nonmodifiable risk factors in these couples is high, but the uptake of PCC remains low. OBJECTIVE: The aim of this study is to identify the preferences and experiences of women and men (patients) trying to become pregnant and of health care providers and other involved professionals regarding mobile health (mHealth), in particular the coaching platform Smarter Pregnancy, and its potential role in PCC...
August 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28799164/preconception-care-for-diabetic-women-for-improving-maternal-and-infant-health
#16
REVIEW
Joanna Tieu, Philippa Middleton, Caroline A Crowther, Emily Shepherd
BACKGROUND: Infants born to mothers with pre-existing type 1 or type 2 diabetes mellitus are at greater risk of congenital anomalies, perinatal mortality and significant morbidity in the short and long term. Pregnant women with pre-existing diabetes are at greater risk of perinatal morbidity and diabetic complications. The relationship between glycaemic control and health outcomes for both mothers and infants indicates the potential for preconception care for these women to be of benefit...
August 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28780659/preconception-counseling-for-women-with-cardiac-disease
#17
REVIEW
Mark A Clapp, Sarah N Bernstein
All providers who care for reproductive-aged women with cardiac disease should assess these patients' desires and plans for pregnancy at every encounter. For those considering pregnancy, preconception counseling, often performed by a maternal-fetal medicine specialist, can help patients understand the potential implications of pregnancy on their health and estimate the risks of an adverse cardiac event prior to conceiving. There are cardiac conditions, such as pulmonary hypertension and aortic stenosis, in which pregnancy may be contraindicated given the high morbidity and mortality; there are tools available to help quantify a patient's risk...
September 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28764640/geographical-differences-in-perinatal-health-and-child-welfare-in-the-netherlands-rationale-for-the-healthy-pregnancy-4-all-2-program
#18
Adja J M Waelput, Meertien K Sijpkens, Jacqueline Lagendijk, Minke R C van Minde, Hein Raat, Hiske E Ernst-Smelt, Marlou L A de Kroon, Ageeth N Rosman, Jasper V Been, Loes C M Bertens, Eric A P Steegers
BACKGROUND: Geographical inequalities in perinatal health and child welfare require attention. To improve the identification, and care, of mothers and young children at risk of adverse health outcomes, the HP4All-2 program was developed. The program consists of three studies, focusing on creating a continuum for risk selection and tailored care pathways from preconception and antenatal care towards 1) postpartum care, 2) early childhood care, as well as 3) interconception care. The program has been implemented in ten municipalities in the Netherlands, aiming to target communities with a relatively disadvantageous position with regard to perinatal and child health outcomes...
August 1, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28760430/is-maternal-body-mass-index-associated-with-neonatal-mortality-a-pooled-analysis-of-nationally-representative-data-from-nine-asian-countries
#19
Rajesh Kumar Rai, Lucky Singh, Prashant Kumar Singh
OBJECTIVE: Children born to mothers with abnormal body mass index (BMI) have increased risk for mortality. The aim of this study was to investigate whether maternal BMI is a risk factor for neonatal death in select Asian countries, including the nature of association between maternal BMI and the discrete timing of neonatal death. METHODS: Nationally representative, the standard Demographic and Health Survey data from nine Asian countries were used. In all, 55 629 mothers reported their index birth; 840 reported neonatal mortality...
September 2017: Nutrition
https://www.readbyqxmd.com/read/28752273/the-association-between-preconception-care-receipt-and-the-timeliness-and-adequacy-of-prenatal-care-an-examination-of-multistate-data-from-pregnancy-risk-assessment-monitoring-system-prams-2009-2011
#20
Meghan K Wally, Larissa R Brunner Huber, L Michele Issel, Michael E Thompson
Objectives Prenatal care (PNC) is a critical preventive health service for pregnant women and infants. While timely PNC has been associated with improved birth outcomes, improvements have slowed since the late 1990s. Therefore, focus has shifted to interventions prior to pregnancy. Preconception care is recommended for all women of reproductive age. This study aimed to examine preconception care and its association with timeliness and adequacy of PNC. Methods This retrospective cohort study used data from a large sample of United States first-time mothers (n = 13,509) who participated in the 2009-2011 Pregnancy Risk Assessment Monitoring System in ten states...
July 27, 2017: Maternal and Child Health Journal
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