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https://www.readbyqxmd.com/read/29334331/transport-mobility-5%C3%A2-years-after-stroke-in-an-urban-setting
#1
Hanna C Persson, Helena Selander
Background People after stroke may have residual problems with mobility that can affect their independence and mode of transport. However, there is limited knowledge about transport mobility several years after stroke. Objective The objective was to survey the outdoor mobility and transportation in an urban setting five years post-stroke. Method This cross-sectional study was based on a mail survey focusing on long-term consequences after stroke. The survey comprises a set of self-evaluated questionnaires and was sent to 457 persons, of whom 281 responded (61...
January 15, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29332255/profiling-attention-and-cognition-enhancing-drugs-in-a-rat-touchscreen-based-continuous-performance-test
#2
Zhiyong Ding, Jordan W Brown, Lynne E Rueter, Eric G Mohler
RATIONALE: A novel rodent continuous performance test (CPT) was developed as one of the goals of the NEWMEDS (Novel Methods leading to New Medications in Depression and Schizophrenia) consortium to improve its translatability to the CPT test used in human subjects. OBJECTIVES: The objective of the study is to investigate the effects of attention and cognition enhancing drugs in rodent CPT. METHODS: A single cohort of rats were trained to asymptotic performance in the test...
January 13, 2018: Psychopharmacology
https://www.readbyqxmd.com/read/29332112/evaluation-of-effectiveness-of-peer-education-on-smoking-behavior-among-high-school-students
#3
Nurcan Bilgiç, Türkan Günay
To evaluate the effectiveness of peer education on changing the smoking behavior of high schoolage children's.  Methods: In this interventional study; transtheoretical model, which is one of the cognitive-behavioral models was used for application of the peer education. Study was conducted in Izmir during 2011-2012 education period and included 338 students from 2 high schools The independent variable of the study is peer training.  Descriptive variables for a student are age, gender, tendecy of friends to smoke inside and outside the school,  the age they have first experienced the habit,  reasons for nicotine consumption,  levels of addiction,  chatting about smoking and related harms...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332036/relationships-between-lower-olfaction-and-brain-white-matter-lesions-in-elderly-subjects-with-mild-cognitive-impairment
#4
Juliette Heinrich, Jean-Sébastien Vidal, Axelle Simon, Anne-Sophie Rigaud, Olivier Hanon, Jacques Epelbaum, Cecile Viollet, Emmanuelle Duron
BACKGROUND: Olfactory impairment is reported in mild cognitive impairment (MCI) and Alzheimer's disease (AD) and is associated with hippocampal atrophy. In elderly people, dementia with AD neuropathology and white matter lesions (WML) is common. In this context, olfactory impairment could also depend on the presence of WML. OBJECTIVE: To assess the cross-sectional relationship between olfaction and WML in elderly subjects with MCI. METHODS: Consecutive subjects, >65 years old, diagnosed as MCI after a comprehensive neuropsychological assessment in an expert memory center, with a brain MRI performed within a year and without major depressive state, were included...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29331264/altered-levels-of-the-splicing-factor-muscleblind-modifies-cerebral-cortical-function-in-mouse-models-of-myotonic-dystrophy
#5
Gang Chen, Russell E Carter, John D Cleary, Tammy S Reid, Laura P Ranum, Maurice S Swanson, Timothy J Ebner
Myotonic dystrophy (DM) is a progressive, multisystem disorder affecting skeletal muscle, heart, and central nervous system. In both DM1 and DM2, microsatellite expansions of CUG and CCUG RNA repeats, respectively, accumulate and disrupt functions of alternative splicing factors, including muscleblind (MBNL) proteins. Grey matter loss and white matter changes, including the corpus callosum, likely underlie cognitive and executive function deficits in DM patients. However, little is known how cerebral cortical circuitry changes in DM...
January 10, 2018: Neurobiology of Disease
https://www.readbyqxmd.com/read/29330827/profiling-online-poker-players-are-executive-functions-correlated-with-poker-ability-and-problem-gambling
#6
Mauro Schiavella, Matteo Pelagatti, Jerker Westin, Gabriele Lepore, Paolo Cherubini
Poker playing and responsible gambling both entail the use of the executive functions (EF), which are higher-level cognitive abilities. This study investigated if online poker players of different ability showed different performances in their EF and if so, which functions were the most discriminating for their playing ability. Furthermore, it assessed if the EF performance was correlated to the quality of gambling, according to self-reported questionnaires (PGSI, SOGS, GRCS). Three poker experts evaluated anonymized poker hand history files and, then, a trained professional administered an extensive neuropsychological test battery...
January 12, 2018: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29330003/effects-of-5-ht5a-receptor-blockade-on-amnesia-or-forgetting
#7
L Aparicio-Nava, L A Márquez-García, A Meneses
Previously the effects (0.01-3.0 mg/kg) of post-training SB-699551 (a 5-HT5A receptor antagonist) were reported in the associative learning task of autoshaping, showing that SB-699551 (0.1 mg/kg) decreased lever-press conditioned responses (CR) during short-term (STM; 1.5-h) or (3.0 mg/kg) long-term memory (LTM; 24-h); relative to the vehicle animals. Moreover, as pro-cognitive efficacy of SB-699551 was reported in the ketamine-model of schizophrenia. Hence, firstly aiming improving performance (conditioned response, CR), in this work autoshaping lever-press vs...
January 9, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29329670/motor-skill-interventions-in-children-with-developmental-coordination-disorder-a-systematic-review-and-meta-analysis
#8
REVIEW
Jane J Yu, Cindy H P Sit, Angus F Burnett
OBJECTIVES: To determine the characteristics and effectiveness of motor skill interventions in children with developmental coordination disorder (DCD) and to identify potential moderators of training effects using meta-analysis. DATA SOURCES: A search was conducted in six databases (CINAHL Plus, Cochrane Library, Embase, Eric, PsycInfo, and PubMed) for papers published between 1995 and August 2017 using search items which were grouped in three components (motor skill interventions, DCD, and age group of interest)...
January 9, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29329340/cognitive-control-moderates-parenting-stress-effects-on-children-s-diurnal-cortisol
#9
Laurel Raffington, Florian Schmiedek, Christine Heim, Yee Lee Shing
This study investigated associations between parenting stress in parents and self-reported stress in children with children's diurnal cortisol secretion and whether these associations are moderated by known stress-regulating capacities, namely child cognitive control. Salivary cortisol concentrations were assessed from awakening to evening on two weekend days from 53 6-to-7-year-old children. Children completed a cognitive control task and a self-report stress questionnaire with an experimenter, while parents completed a parenting stress inventory...
2018: PloS One
https://www.readbyqxmd.com/read/29325715/orexin-knockout-mice-exhibit-impaired-spatial-working-memory
#10
Ruozhi Dang, Qiuhan Chen, Jie Song, Chao He, Jun Zhang, Jianxia Xia, Zhian Hu
Orexins play a crucial role in the maintenance of arousal and are involved in the modulation of diverse physiological process, including cognitive function. Recent data have suggested that orexins are involved in learning and memory processes. The purpose of this study was to assess the effects of orexin deficiency on working memory. A delayed non-matching-to-place T-maze task was used to evaluate spatial working memory in mice lacking orexin prepro-peptide (orexin knockout; KO) and wild-type controls. We demonstrated that the number of correct choices in the orexin KO mice became lower than that of the controls over training...
January 8, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29325701/developmental-cognitive-neuroscience-using-latent-change-score-models-a-tutorial-and-applications
#11
REVIEW
Rogier A Kievit, Andreas M Brandmaier, Gabriel Ziegler, Anne-Laura van Harmelen, Susanne M M de Mooij, Michael Moutoussis, Ian M Goodyer, Ed Bullmore, Peter B Jones, Peter Fonagy, Ulman Lindenberger, Raymond J Dolan
Assessing and analysing individual differences in change over time is of central scientific importance to developmental neuroscience. However, the literature is based largely on cross-sectional comparisons, which reflect a variety of influences and cannot directly represent change. We advocate using latent change score (LCS) models in longitudinal samples as a statistical framework to tease apart the complex processes underlying lifespan development in brain and behaviour using longitudinal data. LCS models provide a flexible framework that naturally accommodates key developmental questions as model parameters and can even be used, with some limitations, in cases with only two measurement occasions...
November 22, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29324862/taking-two-to-tango-fmri-analysis-of-improvised-joint-action-with-physical-contact
#12
Léa A S Chauvigné, Michel Belyk, Steven Brown
Many forms of joint action involve physical coupling between the participants, such as when moving a sofa together or dancing a tango. We report the results of a novel two-person functional MRI study in which trained couple dancers engaged in bimanual contact with an experimenter standing next to the bore of the magnet, and in which the two alternated between being the leader and the follower of joint improvised movements. Leading showed a general pattern of self-orientation, being associated with brain areas involved in motor planning, navigation, sequencing, action monitoring, and error correction...
2018: PloS One
https://www.readbyqxmd.com/read/29324745/proof-of-concept-study-of-an-at-home-engaging-digital-intervention-for-pediatric-adhd
#13
Naomi O Davis, Jeffrey Bower, Scott H Kollins
OBJECTIVE: Pharmacological and behavioral therapies have limited impact on the distinct neurocognitive impairments associated with ADHD, and existing cognitive training programs have shown limited efficacy. This proof-of-concept study assessed treatment acceptability and explored outcomes for a novel digital treatment targeting cognitive processes implicated in ADHD. METHOD: Participants included 40 children with ADHD and 40 children without ADHD. Following psychiatric screening, ADHD ratings, and baseline neuropsychological measures, participants completed 28-days of at-home treatment...
2018: PloS One
https://www.readbyqxmd.com/read/29324562/effectiveness-of-interventions-to-prevent-pre-frailty-and-frailty-progression-in-older-adults-a-systematic-review
#14
João Apóstolo, Richard Cooke, Elzbieta Bobrowicz-Campos, Silvina Santana, Maura Marcucci, Antonio Cano, Miriam Vollenbroek-Hutten, Federico Germini, Barbara D'Avanzo, Holly Gwyther, Carol Holland
OBJECTIVE: To summarize the best available evidence regarding the effectiveness of interventions for preventing frailty progression in older adults. INTRODUCTION: Frailty is an age-related state of decreased physiological reserves characterized by an increased risk of poor clinical outcomes. Evidence supporting the malleability of frailty, its prevention and treatment, has been presented. INCLUSION CRITERIA: The review considered studies on older adults aged 65 and over, explicitly identified as pre-frail or frail, who had been undergoing interventions focusing on the prevention of frailty progression...
January 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29324357/a-pilot-study-of-the-role-of-the-claustrum-in-attention-and-seizures-in-rats
#15
Arezou Bayat, Sweta Joshi, Sahar Jahan, Phillip Connell, Komei Tsuchiya, David Chau, Tanvir Syed, Patrick Forcelli, Mohamad Z Koubeissi
OBJECTIVE: The claustrum has been implicated in consciousness, and MRIs of patients with status epilepticus have shown increased claustral signal intensity. In an attempt to investigate the role of claustrum in cognition and seizures, we (1) assessed the effect of high-frequency stimulation (HFS) of the claustrum on performance in the operant chamber; (2) studied interclaustral and claustrohippocampal connectivity through cerebro-cerebral evoked potentials (CCEPs); and (3) investigated the role of claustrum in kainate-induced (KA) seizures...
January 5, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29324073/rapid-improvement-on-a-temporal-attention-task-within-a-single-session-of-high-frequency-transcranial-random-noise-stimulation
#16
Sarah C Tyler, Federica Contò, Lorella Battelli
This study explored the modulatory effects of high-frequency transcranial random noise stimulation (tRNS) on visual sensitivity during a temporal attention task. We measured sensitivity to different onset asynchronies during a temporal order judgment task as a function of active stimulation relative to sham. While completing the task, participants were stimulated bilaterally for 20 min over either the TPJ or the human middle temporal area. We hypothesized that tRNS over the TPJ, which is critical to the temporal attention network, would selectively increase cortical excitability and induce cognitive training-like effects on performance, perhaps more so in the left visual field [Matthews, N...
January 11, 2018: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29323794/skills-transfer-to-sinus-surgery-via-a-low-cost-simulation-based-curriculum
#17
R Alex Harbison, Jennifer Dunlap, Ian M Humphreys, Greg E Davis
BACKGROUND: Surgical skill development outside the operating room aims to improve technique and subsequent patient safety. The purpose of this study was to evaluate the correlation between technical and cognitive skills with cadaveric endoscopic sinus surgery (ESS) performance and change in ESS performance before and after implementation of a dedicated ESS simulation-based and knowledge-based curriculum. METHODS: A before-after study design was implemented among 10 medical students and 10 junior otolaryngology residents...
January 11, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29322428/feasibility-of-the-evidence-based-cognitive-telerehabilitation-program-remind-for-patients-with-primary-brain-tumors
#18
Sophie D van der Linden, Margriet M Sitskoorn, Geert-Jan M Rutten, Karin Gehring
Many patients with primary brain tumors experience cognitive deficits. Cognitive rehabilitation programs focus on alleviating these deficits, but availability of such programs is limited. Our large randomized controlled trial (RCT) demonstrated positive effects of the cognitive rehabilitation program developed by our group. We converted the program into the iPad-based cognitive rehabilitation program ReMind, to increase its accessibility. The app incorporates psychoeducation, strategy training and retraining...
January 10, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29320335/physician-intervention-and-chinese-americans-colorectal-cancer-screening
#19
Judy Huei-Yu Wang, Grace X Ma, Wenchi Liang, Yin Tan, Kepher H Makambi, Roucheng Dong, Sally W Vernon, Shin-Ping Tu, Jeanne S Mandelblatt
OBJECTIVE: We conducted a cluster-randomized trial evaluating an intervention that trained Chinese-American primary care physicians to increase their Chinese patients' colorectal cancer (CRC) screening. METHODS: Twenty-five physicians (13 randomized to the intervention arm and 12 to the control arm) and 479 of their patients (aged 50-75 and nonadherent to CRC screening guidelines) were enrolled. The intervention, guided by Social Cognitive Theory, included a communication guide and 2 in-office training sessions to enhance physicians' efficacy in com- municating CRC screening with patients...
January 1, 2018: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29319610/the-effectiveness-of-online-pain-resources-for-health-professionals-a-systematic-review-with-subset-meta-analysis-of-educational-intervention-studies
#20
Christina Liossi DPsych, Alessandro Failo PhD, Daniel E Schoth PhD, Glyn Williams Md, Richard Howard Md
Online educational interventions are increasingly developed for health professionals and students, although graduate and undergraduate medical curricular often contain limited information about how to assess and manage pain. This study reviews the literature on the effectiveness of pain-related online educational resources. Studies were identified via a search of Medline, PsychINFO, Web of Science, CINAHL, PubMed, Scopus, Cochrane Library, Google Scholar and OpenGrey databases. Search terms included three concept blocks: (i) type of intervention - online education, computer-based, e-learning, web-based, and internet-based; (ii) population - pediatrician, physician, nurse, psychologist, medical; (iii) outcome - pain*...
January 9, 2018: Pain
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