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https://www.readbyqxmd.com/read/28108119/age-of-onset-of-hypertension-and-risk-of-dementia-in-the-oldest-old-the%C3%A2-90-study
#1
María M Corrada, Kathleen M Hayden, Annlia Paganini-Hill, Szofia S Bullain, Jaime DeMoss, Colette Aguirre, Ron Brookmeyer, Claudia H Kawas
INTRODUCTION: We investigated the association between age of onset of hypertension and dementia risk in an oldest-old cohort. METHODS: Participants are from The 90+ Study, a population-based longitudinal study of people aged 90+ who are survivors from the Leisure World Cohort Study. We estimated hypertension onset age using self-reported information from The 90+ Study and Leisure World Cohort Study, collected about 20 years earlier. A total of 559 participants without dementia were followed every 6 months for up to 10 years...
January 6, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28071922/anxiety-symptoms-and-risk-of-dementia-and-mild-cognitive-impairment-in-the-oldest-old-women
#2
Ahmed M Kassem, Mary Ganguli, Kristine Yaffe, Joseph T Hanlon, Oscar L Lopez, John W Wilson, Kristine Ensrud, Jane A Cauley
OBJECTIVES: Research is limited and findings conflict regarding anxiety as a predictor of future cognitive decline in the oldest old persons. We examined the relationship between levels of and changes in anxiety symptoms, and subsequent dementia and mild cognitive impairment (MCI) in the oldest old women. METHOD: We conducted secondary analyses of data collected from 1425 community-dwelling women (mean age = 82.8, SD ±3.1 years) followed on average for five years...
January 10, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28032231/outcome-following-surgical-treatment-of-chronic-subdural-hematoma-in-the-oldest-old-population
#3
Christopher Munoz-Bendix, Robert Pannewitz, Daniel Remmel, Hans-Jakob Steiger, Bernd Turowski, Phillip Jorg Slotty, Marcel Alexander Kamp
As a result of the demographic shift in western societies, the mean age at presentation of patients suffering from chronic subdural hematomas (cSDH) is increasing. Therapeutic strategies, surgical and non-surgical, need to be reevaluated and adapted accordingly. Age is considered to be a positive risk factor for a higher perioperative morbidity and mortality. The purpose of this study is to determine if old age (≥85 years) should be seen as a contraindication for surgical treatment. Two groups (56 patients each) with cSDH over and below 85 years of age from a single neurosurgical department with well-defined surgical treatment guidelines were retrospectively analyzed...
December 28, 2016: Neurosurgical Review
https://www.readbyqxmd.com/read/28032140/verbal-and-visual-divergent-thinking-in-aging
#4
Massimiliano Palmiero, Raffaella Nori, Laura Piccardi
According to the peak and decline model divergent thinking declines at a specific age (in or after middle age). However, if divergent thinking declines steadily in aging still has to be clarified. In order to explore the age-related changes in verbal and visual divergent thinking, in the present study a sample of 159 participants was divided in five age groups: young adults (18-35 years), middle-aged adults (36-55), young old (56-74), old (75-85) and the oldest-old (86-98). Two divergent thinking tasks were administered: the alternative uses for cardboard boxes, aimed at assessing verbal ideational fluency, flexibility and originality; the completion drawing task, aimed at assessing visual ideational fluency, flexibility and originality...
December 28, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28017957/-development-of-osteoporosis-drugs-the-past-the-present-and-the-future
#5
Shinya Tanaka
From 1990s to 2000s, new drugs for osteoporosis have been developed, and the bone metabolism researches have livened up. In those days, many a people gathered to the meeting from many countries, and the each booth of pharmaceutics was proud of its preeminence. The dedications by the society and its members have had osteoporosis diagnostics developed, the anchor drugs become prevalent, and the number of fractures reduced. Although the brilliant effects of Romosozumab and Abaloparatide were presented in the meeting held this year, the members had to accept the convergence state of new drug developments...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28011804/shape-of-the-association-between-income-and-mortality-a-cohort-study-of-denmark-finland-norway-and-sweden-in-1995-and-2003
#6
Laust H Mortensen, Johan Rehnberg, Espen Dahl, Finn Diderichsen, Jon Ivar Elstad, Pekka Martikainen, David Rehkopf, Lasse Tarkiainen, Johan Fritzell
OBJECTIVES: Prior work has examined the shape of the income-mortality association, but work has not compared gradients between countries. In this study, we focus on changes over time in the shape of income-mortality gradients for 4 Nordic countries during a period of rising income inequality. Context and time differentials in shape imply that the relationship between income and mortality is not fixed. SETTING: Population-based cohort study of Denmark, Finland, Norway and Sweden...
December 23, 2016: BMJ Open
https://www.readbyqxmd.com/read/27995743/anticholinergic-exposure-in-a-cohort-of-adults-aged-80-years-and-over-associations-of-the-marante-scale-with-mortality-and-hospitalisation
#7
Maarten Wauters, Therese Klamer, Monique Elseviers, Bert Vaes, Olivia Dalleur, Jan Degryse, Carlos Durán, Thierry Christiaens, Majda Azermai, Robert Vander Stichele
Anticholinergics are frequently prescribed for older adults and can lead to adverse drug events. The novel MARANTE (Muscarinic Acetylcholinergic Receptor ANTagonist Exposure) scale measures the anticholinergic exposure by incorporating potency and dosages of each medication into its calculations. The aims were to assess prevalence and intensity of the anticholinergic exposure in a longitudinal cohort study of community-dwelling patients aged 80 years and over (n=503) and to study the impact on mortality and hospitalisation...
December 20, 2016: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27968835/psychological-wellbeing-and-all-cause-mortality-in-the-oldest-old-in-china-a-longitudinal-survey-based-study
#8
Enying Gong, Yechu Hua, Lijing L Yan
BACKGROUND: Although the relationship between psychological wellbeing and physical health has been the subject of many studies among middle-aged and older adults, little is known about whether psychological wellbeing is associated with mortality among the fastest growing population segment-the oldest old (aged ≥80 years). METHODS: This study included 18 676 adults aged 80-122 years from the Chinese Longitudinal Healthy Longevity Survey, conducted in 22 of 31 provinces in China in 1998 and followed up in 2000, 2002, 2005, 2008-2009, 2011-12, and 2014...
October 2016: Lancet
https://www.readbyqxmd.com/read/27966402/-colorectal-cancer-surgery-in-the-oldest-dutch-patients-retrospective-analysis-of-two-national-databases-covering-2011-and-2012
#9
N M Verweij, A H W Schiphorst, H A Maas, D D E Zimmerman, F van den Bos, A Pronk, I H M Borel Rinkes, M E Hamakers
OBJECTIVE: Adequate decision-making concerning elderly patients with colorectal cancer requires accurate information regarding the risks of treatment. We analysed the post-operative outcomes and survival following colorectal resections in the oldest old patients (≥ 85 years old). DESIGN: Retrospective study. METHOD: We analysed the data from 2011 and 2012 of all patients with colorectal carcinoma, stage I-III, from two national databases, namely the Dutch Surgical Colorectal Audit registry (DSCA) and the Netherlands Cancer Registry (NKR)...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27965430/timing-of-percutaneous-endoscopic-gastrostomy-for-acute-ischemic-stroke-an-observational-study-from-the-us-nationwide-inpatient-sample
#10
Benjamin P George, Adam G Kelly, George P Albert, David Y Hwang, Robert G Holloway
BACKGROUND AND PURPOSE: Stroke guidelines recommend time-limited trials of nasogastric feeding prior to percutaneous endoscopic gastrostomy (PEG) tube placement. We sought to describe timing of PEG placement and identify factors associated with early PEG for acute ischemic stroke. METHODS: We designed a retrospective observational study to examine time to PEG for ischemic stroke admissions in the Nationwide Inpatient Sample, 2001 to 2011. We defined early PEG placement as 1 to 7 days from admission...
December 13, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27932078/the-utility-of-vacuum-assisted-closure-therapy-for-skin-necrosis-secondary-to-cervical-abscess-in-the-elderly
#11
Tadataka Tsuji, Koichi Satoh, Emi Okuno, Akiko Sobue, Yoshiya Nishide, Susumu Tanaka, Mikihiko Kogo
Vacuum-assisted closure (VAC) systems have been used as negative-pressure dressings in various fields, including decubitus ulcer, trauma, and wound dehiscence. To the best of our knowledge, few reports have examined the utility of VAC therapy for neck abscess in an oldest-old patient. We present here a rare case of neck abscess secondary to parotid abscess, resulting in extensive skin necrosis. Successful management included emergency drainage following epithelial induction through a VAC system without using skin grafting...
December 5, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27927759/cd4-8-ratio-above-5-is-associated-with-all-cause-mortality-in-cmv-seronegative-very-old-women-results-from-the-belfrail-study
#12
Wim Adriaensen, Graham Pawelec, Bert Vaes, Klaus Hamprecht, Evelyna Derhovanessian, Gijs van Pottelbergh, Jean-Marie Degryse, Catharina Matheï
The occurrence and general applicability of the CD4:8 ratio as a surrogate predictor of mortality among the oldest old have only been tested in a few longitudinal studies. Here, the predictive value of CD4:8 ratio for mortality with respect to the role of cytomegalovirus (CMV) infection was investigated. Using polychromatic flow cytometry, the CD4:8 ratio and T-cell subsets of 235 individuals aged 81.5 years or older were analyzed, and mortality data were collected after a mean period of 3.3 years. The hazard for all-cause mortality adjusted for age, comorbidity, and CMV serostatus increased 1...
December 7, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27925145/the-oldest-old-in-the-emergency-department-impact-of-renal-function
#13
T Brünnler, M Drey, G Dirrigl, C Weingart, F Rockmann, C Sieber, U Hoffmann
OBJECTIVES: The ageing population implicates an increasing numbers of older adults attending Emergency Departments (ED). We assessed the effect of estimated glomerular filtration rate as a predictor of clinical outcomes in oldest-old patients ≥ 85 years attending the ED in an university teaching hospital. DESIGN: Within three years, 81831 patient contacts were made in our ED. 7799 (9.5%) were older than 85 years, in whom we analyzed the impact of renal function on various outcome parameters...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27918699/validation-of-questionnaire-assessed-physical-activity-in-comparison-with-objective-measures-using-accelerometers-and-physical-performance-measures-among-community-dwelling-adults-aged-%C3%A2-85-years-in-tokyo-japan
#14
Yuko Oguma, Yusuke Osawa, Michiyo Takayama, Yukiko Abe, Shigeho Tanaka, I-Min Lee, Yasumichi Arai
BACKGROUND: To date, there is no physical activity (PA) questionnaire with convergent and construct validity for the oldest-old. The aim of the present study was to investigate the validity of questionnaire-assessed PA in comparison with objective measures determined by uniaxial and triaxial accelerometers and physical performance measures in the oldest-old. METHODS: Participants were 155 elderly (mean age 90 years) who were examined at the university and agreed to wear an accelerometer for 7 days in the 3-year-follow-up survey of the Tokyo Oldest-Old Survey of Total Health...
December 5, 2016: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/27918203/intergenerational-support-and-life-satisfaction-of-young-old-and-oldest-old-adults-in-china
#15
Jia Chen, Lucy P Jordan
OBJECTIVES: This study investigated variation across different old-age groups in the association between intergenerational support and elderly life satisfaction in China, taking into account both exchange patterns and different types of support. METHOD: Using the first two waves (2010 and 2012) of China Family Panel Studies, we applied the fixed-effect approach to examine the moderating effect of age separately for exchange patterns and different types of intergenerational support...
December 5, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27912849/the-othering-of-old-age-insights-from-postcolonial-studies
#16
Silke van Dyk
When it comes to old age, we are witnessing almost revolutionary changes at the present time. After decades of ignorance and lack of public interest, old age has fundamentally been re-negotiated. A diverse range of authors have diagnosed the growing bifurcation of old age into a rather independent and capable Third Age and a deep old Fourth Age that is characterized by sickness, frailty and dependency. Against this backdrop, many gerontologists claim that the so-called young-old are praised and valued for their (ongoing) "sameness" in terms of midlife-norms and capabilities, whereas the oldest old are increasingly excluded from humanity by radical "othering"...
December 2016: Journal of Aging Studies
https://www.readbyqxmd.com/read/27901180/ultrasonographic-assessment-of-thyroid-volume-in-oldest-old-individuals
#17
Glaucia Cruzes Duarte, Lara Miguel Quirino Araujo, Felix Magalhães, Clineu Mello Almada, Maysa Seabra Cendoroglo
Objective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area. Subjects and methods: The study included 81 independent elderly individuals aged ≥ 80 years (65 [80.2%] women). We determined these individuals' anthropometric characteristics, body mass index (BMI), and lean body mass, as well as thyroid volume and echogenicity by ultrasonography...
November 24, 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27832329/burden-of-multimorbidity-and-outcome-in-ambulatory-geriatric-hemodialysis-patients-report-from-the-qin-registry-in-germany
#18
Gabriele Röhrig, Maria Cristina Polidori, Katherine Rascher, Mathias Schaller, Thomas Benzing, Gero von Gersdorff
BACKGROUND: Patients with end-stage renal disease (ESRD) requiring hemodialysis are typically characterized by multimorbidity and increasingly by advanced age; however, there are few data on their geriatric needs. OBJECTIVE: The aim of the study was to evaluate the clinical characteristics of a large cohort of incident patients in ambulatory hemodialysis units with a particular focus on those aged over 80 years in Germany. METHODS: The electronic patient registry of the Board of Trustees (Kuratorium) for Dialysis and Kidney Transplantation (KfH) was searched for all patients who began hemodialysis in 1 of the 191 units between 2007 and 2013 and were 65 years and older...
November 10, 2016: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/27823743/the-debilitating-effects-of-chronic-diseases-among-the-oldest-old-in-china
#19
Nai Peng Tey, Siow Li Lai, Jane K L Teh
OBJECTIVES: The aims of this study were to assess the current sharp rise in chronic diseases and disabilities with advancing age, and to examine the debilitating effects of chronic diseases among the oldest old in China. STUDY DESIGN AND OUTCOME VARIABLES: This study used data from four waves of the Chinese Longitudinal Health and Longevity Survey (CLHLS) conducted in 2002, 2005, 2008 and 2011. The sample comprised 2137 older adults who were interviewed in 2002 and re-interviewed in the following waves...
December 2016: Maturitas
https://www.readbyqxmd.com/read/27816907/new-horizons-in-design-for-autonomous-ageing
#20
REVIEW
Tischa J M van der Cammen, Armagan Albayrak, Ena Voûte, Johan F M Molenbroek
The world is ageing rapidly. Between 2000 and 2050, the number of people aged ≥65 will double as a proportion of the global population, from 7% to 16%, respectively. By 2050, for the first time in human history, there will be more older people than children (aged 0-14 years) in the population. More distinctive is the tremendous increase in the oldest old aged ≥85. This challenges society to adapt, in order to maximise the health and functional capacity of older people as well as their social participation and security...
November 5, 2016: Age and Ageing
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