Read by QxMD icon Read


Bo Liang, Ling Wu, Hui Xu, Chun Wai Cheung, Wen Ying Fung, Sze Wai Wong, Chi Chiu Wang
BACKGROUND: Current medical treatments for endometriosis are very limited. Progestin and selective progesterone receptor modulators (SPRM) are developed but their efficacy, safety, mechanism and recurrence in endometriosis are not fully studied. METHODS: In order to compare therapeutic, side effects and therapeutic actions of Esmya, Duphaston and Dienogest in endometriosis. Experimental endometriosis was induced by either intraperitoneal or subcutaneous mouse endometrium transplantation...
April 3, 2018: Reproductive Biology and Endocrinology: RB&E
Xiuxian Zhu, Hongjuan Ye, Yonglun Fu
OBJECTIVE: To evaluate endocrine characteristics and clinical outcomes in normal ovulatory patients undergoing controlled ovarian hyperstimulation (COH) with the use of a Duphaston and hMG protocol during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments in combination with frozen-thawed embryo transfer (FET) compared with the characteristics and outcomes of patients undergoing an Utrogestan and hMG protocol. DESIGN: Prospective controlled study...
September 2017: Fertility and Sterility
Ekachai Leeangkoonsathian, Tawiwan Pantasri, Somsak Chaovisitseree, Nuntana Morakot
BACKGROUND: While progesterone affects sleep, different types of it might affect sleep differently. METHODS: One hundred Thai women, who complained of insomnia, visited the Menopause Clinic at Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand from February 2014 to March 2015, and were divided randomly into two groups. Both groups received daily hormonal treatment that included estradiol valerate (progynova) at 1 mg. The first group also received dydrogesterone (duphaston® ) at 10 mg and the second group micronized progesterone (utrogestran® ) at 100 mg...
December 2017: Gynecological Endocrinology
Howard Carp
The objective of this systematic review was to assesses whether the orally acting progestagen, dydrogesterone lowers the incidence of subsequent miscarriage in women with recurrent miscarriage. A computerized search was performed in Medline, Embase and Ovid Medline for original reports with the product name "Duphaston" or "dydrogesterone" and limited to clinical human data. Thirteen reports of dydrogesterone treatment were identified. Two randomized trials and one non-randomized comparative trial were identified, including 509 women who fulfilled the criteria for meta-analysis...
June 2015: Gynecological Endocrinology
Vlatka Tomic, Jozo Tomic, Djurdja Zigmundovac Klaic, Miro Kasum, Krunoslav Kuna
OBJECTIVES: To compare efficacy, satisfaction and tolerability of oral dydrogesterone and micronized vaginal progesterone gel used for luteal supplementation. STUDY DESIGN: Randomized controlled trial. A total of 853 infertile women undergoing IVF/ICSI treatment in University Hospital Center "Sisters of Mercy", Zagreb, Croatia. Luteal support was provided as Crinone 8%(®) vaginal progesterone gel (90mg) administered daily, or oral dydrogesterone Duphaston(®) (2× 10mg) administered two times daily...
March 2015: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Howard Carp
The objective of this systematic review was to assess whether the orally acting progestagen, dydrogesterone lowers the incidence of miscarriage in women with threatened miscarriage. A computerized search was performed in Medline, Embase, and Ovid Medline for original reports with the product name 'Duphaston' or 'dydrogesterone', and limited to clinical human data. Twenty-one reports of dydrogesterone treatment were identified with 1380 patients. Five randomized trials were identified, including 660 women who fulfilled the criteria for meta-analysis...
December 2012: Gynecological Endocrinology
L T Koridze, M A Dzhangidze
A new method of treatment of endometriosis includes combination of surgical and hormonal therapy. Surgical method included excision of tissue with endometriosis, while the hormonal therapy involved the combination of dufaston and reaferon-EC (recombinant interferon alpha 2b). The aim of this study was to develop effective method of treatment of infertility caused by endometriosis using combination of dufaston and reaferon. There were 114 patients under observation who suffered from endometriosis and infertility...
November 2005: Georgian Medical News
Tomasz Banach, Lukasz Dobrek, Tomasz Milewicz, Władysława Kolasińska-Kloch, Józef Krzysiek, Piotr J Thor
BACKGROUND: Increased incidence of cardiovascular diseases frequently reported in postmenopausal women may follow disturbed activity of cardiac autonomic nervous system (cANS). Our purpose was to evaluate the influence of continuous combined hormonal replacement therapy (ccHRT) on cANS reflected by parameters of heart rate variability (HRV). METHOD: Thirty four healthy postmenopausal women aged 56+/-6 years (7+/-4 years after last menorrhoea) were divided into 2 equal groups--women receiving ccHRT (serum estradiol--81+/-75 ng/l, FSH--45+/-27 IU/l) and control group (serum estradiol--31+/-45 ng/l, FSH--74+/-32 IU/l)...
2004: Przegla̧d Lekarski
Gérard Samuel Chetrite, Hubert H Thole, Jean-Claude Philippe, Jorge Raul Pasqualini
Estradiol (E2) is one of the main factors which control the growth and evolution of breast cancer. Consequently, to block the formation of E2 inside cancer cells has been an important target in recent years. Breast cancer cells possess all the enzymatic systems (e.g. sulfatase, aromatase, 17beta-hydroxysteroid dehydrogenase [17beta-HSD]) involved in the conversion of estrogen precursors into E2. Sulfotransferase, which converts estrogen to its sulfate, is also present in this tumoral tissue. Duphaston is a synthetic progestogen with properties similar to the natural progesterone...
May 2004: Anticancer Research
G M Makhmudova, D K Nazhmutdinova, D Kh Gafarova, Iu D Lukmanova
The authors present outcomes of inspection of 300 women suffering from genital endometriosis. Localization and thermocoagulation of endometriosis was performed by diagnostic and operative laparoscopy. After operation women were treated with hormonomodulative therapy. Patients were divided in five groups, depending on prescribed treatment. The authors concluded that the most effective is therapy with progestine dydrogesterone (Duphaston). For comparison there are presented groups of patients without hormonal treatment after operation...
2003: Akusherstvo i Ginekologii︠a︡
No abstract text is available yet for this article.
April 1965: Journal of Obstetrics and Gynaecology of the British Commonwealth
No abstract text is available yet for this article.
October 1964: International Journal of Fertility
No abstract text is available yet for this article.
June 1962: Obstetrics and Gynecology
Faheem F Zayed, Mohammad F El-Jallad, Haifa A Al-Chalabi
OBJECTIVE: To determine the efficacy of luteal phase support with human chorionic gonadotropin (hCG) or oral progesterone during human menopausal gonadotropin (hMG) ovulation induction. METHODS: Between September 1999 and March 2001, a total of 91 couples with infertility were recruited at Al-Hammadi Hospital, Riyadh, Kingdom of Saudi Arabia and Badeea Hospital, Jordan. In this prospective trial 46 couples were allocated to luteal phase support with hCG injections, while 45 couples were allocated to Duphaston (oral progestogens) as luteal support...
January 2003: Saudi Medical Journal
A M Borissova, T Tankova, P Kamenova, L Dakovska, R Kovacheva, G Kirilov, N Genov, B Milcheva, D Koev
The aim of the present study was to evaluate the effect of three different combinations of hormone replacement therapy (HRT) on insulin secretion, peripheral insulin sensitivity, serum lipid levels and parameters of oxidative stress. Seven type II diabetic women of mean age 55.4 +/- 4.7 years, who had been menopausal for an average of 5 years, were enrolled in the study. Phases of insulin secretion--first (FPIS) and second (SPIS)--and the area under the curve (AUC) for insulin secretion were studied during an intravenous glucose tolerance test (IVGTT)...
February 2002: Gynecological Endocrinology
K P Tumasian, V V Bespoiasnaia, I V Voronovskaia
A total of 16 women with endometriosis 25 to 36 years old were examined. Of these, 6 presented with primary infertility, 10--with secondary intertility, 7 female patients had endometriosis concurrent with other localizations. The treatment was with duphaston (dydrogesteron), 10 mg (5 mg twice a day) beginning from day 5 till 25 of the menstrual cycle for 6 months. The control echography and hysteroscopy permitted ascertaining regression of endometrioid foci in 13 female patients. According to the histological findings in 15 women the endometrium corresponded to the proliferative phase of the menstrual cycle, with its focal hyperplasia having been noted in 1 woman...
May 2001: Likars'ka Sprava
J Korczyński
Oral administration of 20 mg per day Dydrogesterone was recommended in 28 pregnancies as a prevention of risks due to ultrasound guided amniocentesis. Reduction rate (3.6% vs. 5.0%) of uterine cramping and/or uterine contraction wave, observed in US were noticed comparing to the control (n = 40). No spontaneous abortion was noticed in both groups during two weeks follow up. Amniotic fluid leakage was noticed in 2.5% of control comparing to none in the Dydrogesterone group.
August 2000: Ginekologia Polska
C E Overton, P C Lindsay, B Johal, S A Collins, N C Siddle, R W Shaw, D H Barlow
OBJECTIVE: To compare dydrogesterone with placebos in the treatment of minimal to mild endometriosis. DESIGN: Prospective, double-blind, randomized study. SETTING: Three Obstetrics and Gynaecology Departments in the United Kingdom. PATIENTS: Sixty-two premenopausal women with complaints of pain (n = 12) and infertility with or without pain (n = 50) with minimal to mild endometriosis diagnosed at laparoscopy. Thirty-nine women had a laparoscopy after treatment and 56 women were followed up 12 months after treatment...
October 1994: Fertility and Sterility
B Kaplan, A Neri, E Kitai, Y Pardo, M Blum, J Friedman
The purpose of this study was to investigate whether treatment for prevention of osteoporosis by means of postmenopausal hormone replacement therapy (HRP) and daily exercise, had any effect on ratios of urinary calcium:creatinine (Ca:Cre) and magnesium:creatinine (Mg:Cre). A group of 33 early postmenopausal women (menopause onset 12-18 months previously), mean age 49.12 years, were treated during 6 months with low doses of transdermal estrogen (Estraderm TTS 25 micrograms, Ciba-Geigy) opposed by oral progestogen (Duphaston 10 mg, 10 days every month), and daily exercise (walking for 1 hour)...
1994: Clinical and Experimental Obstetrics & Gynecology
J R Strecker
The symptomatology of the premenstrual syndrome is frequently seen in general and gynecological practice. The aim of this study was to examine the therapeutical effect of dydrogesterone (Duphaston) on the typical premenstrual complaints as depression, headache, edema, mastodynia, dysmenorrhea and bleeding irregularities. Oral administration of 20 mg dydrogesterone b.i.d. during the second half of the menstrual cycle could well relieve the complaints mentioned above. Best results of treatment were obtained in cases of dysmenorrhea, bleeding irregularities, depression and edema...
January 31, 1980: Fortschritte der Medizin
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"