Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
A Conforti, G G Iorio, R Di Girolamo, M Y Rovetto, S Picarelli, F Cariati, R Gentile, A D'Amato, O Gliozheni, B Fioretti, C Alviggi
BACKGROUND: Resveratrol is a natural polyphenolic compound present in plants and red wine with many potential health benefits. This compound has various anti-inflammatory and anti-tumor properties and can improve cellular mitochondrial activity. This trial was designed to evaluate the effect on the outcome of IVF of Resveratrol supplementation in women > 35 years with good ovarian reserve (AMH > 1.2 ng/ml). Women were randomized to receive or placebo or Resveratrol (150 mg per day) for three months preceding the ovarian stimulation (OS)...
April 15, 2024: Journal of Ovarian Research
#2
JOURNAL ARTICLE
Hannah E Laue, Bruce P Lanphear, Antonia M Calafat, Kim M Cecil, Aimin Chen, Yingying Xu, Heidi J Kalkwarf, Juliette C Madan, Margaret R Karagas, Kimberly Yolton, Abby F Fleisch, Joseph M Braun
BACKGROUND: Triclosan is an endocrine-disrupting chemical, but associations with pubertal outcomes remain unclear. We examined associations of gestational and childhood triclosan with adolescent hormone concentrations and pubertal stage. METHODS: We quantified urinary triclosan concentrations twice during pregnancy and seven times between birth and 12 years in participants recruited from Cincinnati, OH (2003-2006). We averaged concentrations across pregnancy and childhood and separately considered individual exposure periods in multiple informant models...
April 2024: Environmental Epidemiology
#3
JOURNAL ARTICLE
Ahmed M E Shipa, Khaled A Kahilo, Samir A Elshazly, Ehab S Taher, Nasr E Nasr, Badriyah S Alotaibi, Essam A Almadaly, Mona Assas, Walied Abdo, Tarek K Abouzaid, Abdulati Elsanusi Salem, Damla Kirci, Hesham R El-Seedi, Mohamed S Refaey, Nermin I Rizk, Mustafa Shukry, Doaa A Dourgham
This study examined the protective effects of a Petroselinum Crispum (P. crispum) methanolic extract on reproductive dysfunction induced by acrylamide in male rats. A total of 40 rats were divided into four groups (n=10). The control group received distilled water, the Acrylamide group received 10mg/kg of acrylamide, the P. crispum group received 100mg/kg of P. crispum extract, and the combined group was pretreated with P. crispum for two weeks before co-administration of P. crispum and acrylamide. All administrations were administered orally using a gastric tube for eight weeks...
April 11, 2024: Reproductive Toxicology
#4
JOURNAL ARTICLE
Alexandra P Bielfeld, Juan-Enrique Schwarze, Patrice Verpillat, Monica Lispi, Robert Fischer, Brooke Hayward, Dana Chuderland, Thomas D'Hooghe, Jan-Steffan Krussel
RESEARCH QUESTION: According to real-world data, is recombinant human FSH (r-hFSH) combined with recombinant human LH (r-hLH) or r-hFSH alone more effective for women of advanced maternal age (AMA) in terms of live birth? DESIGN: Non-interventional study comparing the effectiveness of r-hFSH and recombinant r-hLH (2:1 ratio) versus r-hFSH alone for ovarian stimulation during ART treatment in women aged 35-40 years, using real-world data from the Deutsches IVF-Register...
November 12, 2023: Reproductive Biomedicine Online
#5
Samvida S Venkatesh, Laura B L Wittemans, Duncan S Palmer, Nikolas A Baya, Teresa Ferreira, Barney Hill, Frederik Heymann Lassen, Melody J Parker, Saskia Reibe, Ahmed Elhakeem, Karina Banasik, Mie T Bruun, Christian Erikstrup, Bitten A Jensen, Anders Juul, Christina Mikkelsen, Henriette S Nielsen, Sisse R Ostrowski, Ole B Pedersen, Palle D Rohde, Erik Sorensen, Henrik Ullum, David Westergaard, Asgeir Haraldsson, Hilma Holm, Ingileif Jonsdottir, Isleifur Olafsson, Thora Steingrimsdottir, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Jessica Figueredo, Minna K Karjalainen, Anu Pasanen, Benjamin M Jacobs, Nikki Hubers, Margaret Lippincott, Abigail Fraser, Deborah A Lawlor, Nicholas J Timpson, Mette Nyegaard, Kari Stefansson, Reedik Magi, Hannele Laivuori, David A van Heel, Dorret I Boomsma, Ravikumar Balasubramanian, Stephanie B Seminara, Yee-Ming Chan, Triin Laisk, Cecilia M Lindgren
Genome-wide association studies (GWASs) may help inform treatments for infertility, whose causes remain unknown in many cases. Here we present GWAS meta-analyses across six cohorts for male and female infertility in up to 41,200 cases and 687,005 controls. We identified 21 genetic risk loci for infertility ( P ≤5E-08), of which 12 have not been reported for any reproductive condition. We found positive genetic correlations between endometriosis and all-cause female infertility ( r g =0.585, P =8.98E-14), and between polycystic ovary syndrome and anovulatory infertility ( r g =0...
March 20, 2024: medRxiv
#6
JOURNAL ARTICLE
Dian Anindita Lubis, Imam Subekti, Em Yunir, Cosphiadi Irawan, Andon Hestiantoro, Silvia Werdhy Lestari, Aria Kekalih, Merci Monica Br Pasaribu, Santi Syafril
BACKGROUND: Beta thalassemia is a lifelong disease involving malformed red blood cells (RBC). One of the disease's complications is hypogonadism, in which adults tend to exhibit regression in sexual characteristics, experience sexual dysfunction, and therefore have a lower quality of life. Around 3-10% of the Indonesian population carries the beta-thalassemia gene. This study aimed to see the proportions of hypogonadism in transfusion-dependent thalassemia patients and its contributing factors...
January 2024: Acta Medica Indonesiana
#7
JOURNAL ARTICLE
Rooshna Mohsin, Victor Y Fujimoto, Aubrey L Galusha, Patrick J Parsons, Jenna R Krall, Celeste D Butts-Jackson, Evelyn Mok-Lin, Michael S Bloom
INTRODUCTION: Exposure to trace elements has been associated with ovarian response in experimental studies. We conducted a hypothesis-generating study of associations between ovarian follicular fluid (FF) trace elements and measures of ovarian response among women using in vitro fertilization (IVF). METHODS: We collected ovarian FF specimens from 56 women. We determined concentrations (μg/L) of 11 trace elements using inductively coupled plasma-tandem mass spectrometry...
March 28, 2024: Environmental Research
#8
JOURNAL ARTICLE
Marzieh Saei Ghare Naz, Mahbanoo Farhadi-Azar, Mahsa Noroozzadeh, Maryam Farahmand, Fahimeh Ramezani Tehrani
BACKGROUND: Today, co-occurrence of hormonal changes during menopause and the risk of cardio-metabolic disorders have been well studied. We aimed to explore the association of circulating levels of follicle-stimulating hormone (FSH) with diabetes (DM) among postmenopausal women. METHOD: In this Systematic review and meta-analysis the search was performed on PubMed, Scopus, Web of sciences, Epistemonikos, and Cochrane library until the September 2023. Risk of bias was assessed by Newcastle-Ottawa Quality Assessment Scale...
March 30, 2024: Journal of Clinical Endocrinology and Metabolism
#9
JOURNAL ARTICLE
Xinyu Li, Yunying Lin, Xiaoyue Cheng, Guangxin Yao, Jufang Yao, Shuanggang Hu, Qinling Zhu, Yuan Wang, Ying Ding, Yao Lu, Jia Qi, Hanting Zhao, Xuejiao Bian, Yanzhi Du, Kang Sun, Hugo Vankelecom, Yun Sun
STUDY QUESTION: Does ovarian ferroptosis play an active role in the development of polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Increased ovarian ferroptosis was present in PCOS ovaries and the inhibition of ferroptosis with ferrostatin-1 (Fer-1) ameliorated polycystic ovary morphology and anovulation. WHAT IS KNOWN ALREADY: Programmed cell death plays a fundamental role in ovarian follicle development. However, the types and mechanisms of cell death involved in the ovary are yet to be elucidated...
2024: Human Reproduction Open
#10
JOURNAL ARTICLE
Hira Sayed, Qiongqiong Zhang, Yu Tang, Yanan Wang, Yongpeng Guo, Jianyun Zhang, Cheng Ji, Qiugang Ma, Lihong Zhao
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin found in many agricultural products and can cause reproductive disorders, mainly affecting spermatogenesis in male animals. Rutin (RUT) is a natural flavonoid compound recognized for its significant antioxidant, anti-inflammatory and estrogenic properties. The present study aimed to determine the protective role of RUT against ZEN-induced reproductive toxicity in male mice. Twenty-four adult Kunming male mice were divided into four groups: control, RUT (500 mg/kg RUT), ZEN (10 mg/kg ZEN), ZEN + RUT (500 mg/kg RUT + 10 mg/kg ZEN), with six replicates per treatment...
February 29, 2024: Toxins
#11
JOURNAL ARTICLE
Sara Naseri, Maria I Avrutsky, Carlo Capati, Khevna Desai, Ruben Alvero, Paul D Blumenthal
OBJECTIVE: To explore whether menstrual blood collected via a modified menstrual pad is a surrogate for venous blood drawn in analyzing hemoglobin A1c (HbA1c) and fertility-associated hormones. DESIGN: Cross-sectional study. SETTING: Clinical testing laboratory. PATIENTS: This study included 152 female participants who have regular menses, aged 19-50 years old. INTERVENTIONS: Participants collected menstrual effluent using a menstrual pad modified with a removable dried blood spot (DBS) strip...
March 2024: F&S reports
#12
JOURNAL ARTICLE
M Del Mar Vidal, Francisca Martínez, Ignacio Rodríguez, Nikolaos P Polyzos
STUDY QUESTION: Is there any difference in ovarian response and embryo ploidy following progesterone-primed ovarian stimulation (PPOS) using micronized progesterone or GnRH antagonist protocol? SUMMARY ANSWER: Pituitary downregulation with micronized progesterone as PPOS results in higher number of oocytes retrieved and a comparable number of euploid blastocysts to a GnRH antagonist protocol. WHAT IS KNOWN ALREADY: Although the GnRH antagonist is considered by most the gold standard protocol for controlling the LH surge during ovarian stimulation (OS) for IVF/ICSI, PPOS protocols are being increasingly used in freeze-all protocols...
March 18, 2024: Human Reproduction
#13
JOURNAL ARTICLE
W Ezzat, W K Abdelbasset, R S Hussien, A R Azab, A Sulieman, S Yousry
OBJECTIVE: Thyroid hormones are essential for regulating metabolism, reproduction, and growth. Hypothyroidism is connected with lower sperm count and motility, leading to male infertility. Oxidative stress is likely to be linked to this interaction. Melatonin, being known as an oxidative scavenger, may offer a feasible treatment method for reproductive dysfunction accompanying hypothyroidism in adult male rats. The purpose of this investigation was to determine the mechanism by which melatonin treatment affected spermatogenic and steroidogenic function in an experimental model-induced hypothyroidism in adult male rats...
March 2024: European Review for Medical and Pharmacological Sciences
#14
JOURNAL ARTICLE
Sarit Avraham, Michal Youngster, Gil Yerushalmi, Yekaterina Belov, Itai Gat, Alon Kedem, Odelia Yaakov, Yariv Gidoni, Jonathan Barkat, Ohad Baruchin, Ariel Hourvitz
This prospective study aimed to test the ability of follicular GnRH agonist challenge test (FACT) to predict suboptimal response to GnRH agonist trigger, assessed by LH levels post ovulation trigger in non-medical oocyte cryopreservation program. The study included 91 women that underwent non-medical fertility preservation. On day two to menstrual cycle, blood tests were drawn (basal Estradiol, basal FSH, basal LH, Progesterone) and ultrasound (US) was performed. On that evening, the women were instructed to inject 0...
March 14, 2024: Scientific Reports
#15
JOURNAL ARTICLE
Mohamed H Elashal, Aida A Abd El-Wahed, Mostafa Abdelgaber Mohamed, Rania Hamad, Mabrouk Attia Abd Eldaim, Shaden A M Khalifa, Badr Aldahmash, Hesham R El-Seedi, Bishoy El-Aarag
Apilarnil, a bee-derived product originating from drone larvae, offers a range of advantageous properties for both humans and animals. It functions as an antioxidant, provides neuroprotection, boosts fertility, and has antiviral capabilities. Additionally, it is a provider of androgenic hormones. These beneficial functions are supported by its chemical composition, which comprises mineral salts, vitamins, carbs, lipids, hormones, and amino acids. The current study aimed to evaluate the ameliorative effect of apilarnil against Bisphenol A (BPA)-induced testicular toxicity in male adult rats...
March 12, 2024: Reproductive Toxicology
#16
JOURNAL ARTICLE
Abrar Mian, Emily Huang, Nathan R Starke, Landon Trost, Sevann Helo
OBJECTIVES: To report our experience using fine needle vasography (FNV) to identify a site of obstruction and determine candidacy for reconstructive procedures in patients presenting with suspected obstructive azoospermia or cryptozoospermia. METHODS: We report a multi-institutional case series of patients with suspected complete or partial obstructive azoospermia. Patients that were included had azoospermia or cryptozoospermia, presence of palpable vasa, testicles ≥12 ml, and FSH <7...
March 12, 2024: Urology
#17
JOURNAL ARTICLE
Chandrima Majumdar, Merve Demir, Steven R Merrill, Mohammad Hashemian, Sheila S David
ConspectusBase excision repair (BER) enzymes are genomic superheroes that stealthily and accurately identify and remove chemically modified DNA bases. DNA base modifications erode the informational content of DNA and underlie many disease phenotypes, most conspicuously, cancer. The "OG" of oxidative base damage, 8-oxo-7,8-dihydroguanine (OG), is particularly insidious due to its miscoding ability that leads to the formation of rare, pro-mutagenic OG:A mismatches. Thwarting mutagenesis relies on the capture of OG:A mismatches prior to DNA replication and removal of the mis-inserted adenine by MutY glycosylases to initiate BER...
March 12, 2024: Accounts of Chemical Research
#18
RANDOMIZED CONTROLLED TRIAL
Qi Chu, Yue-Xin Yu, Jing-Zi Zhang, Yi-Tong Zhang, Jia-Ping Yu
BACKGROUND: This study was designed to explore the effects of flaxseed oil on the metaphase II (MII) oocyte rates in women with decreased ovarian reserve (DOR). METHODS: The women with DOR were divided into a study group (n = 108, flaxseed oil treatment) and a control group (n = 110, no treatment). All patients were treated with assisted reproductive technology (ART). Subsequently, the ART stimulation cycle parameters, embryo transfer (ET) results, and clinical reproductive outcomes were recorded...
2024: Frontiers in Endocrinology
#19
JOURNAL ARTICLE
Tanvi Suresh, Sarah LaPointe, Jaqueline C Lee, Zsolt P Nagy, Daniel B Shapiro, Michael R Kramer, Heather S Hipp, Audrey J Gaskins
OBJECTIVE: To study the relationship between neighborhood deprivation index (NDI) and markers of ovarian reserve and outcomes of controlled ovarian stimulation among young, healthy oocyte donors. DESIGN: Retrospective cohort study. PATIENTS: A total of 547 oocyte donors who underwent 905 oocyte retrieval cycles (2008-2020) at a private fertility center in Sandy Springs, Georgia, United States. INTERVENTIONS: Neighborhood deprivation index was calculated using principal component analysis applied to census-level measures of poverty, employment, household composition, and public assistance, which was then standardized and linked to donor information on the basis of donor residence...
March 8, 2024: Fertility and Sterility
#20
JOURNAL ARTICLE
S Castets, F Albarel, A Bachelot, G Brun, J Bouligand, C Briet, E Bui Quoc, C Cazabat, C Chabbert-Buffet, S Christin-Maitre, C Courtillot, T Cuny, G De Filippo, B Donadille, F Illouz, I Pellegrini, Y Reznik, A Saveanu, N Teissier, P Touraine, M C Vantyghem, J Vergier, J Léger, T Brue, R Reynaud
Pituitary deficiency, or hypopituitarism, is a rare chronic disease. It is defined by insufficient synthesis of one or more pituitary hormones (growth hormone, TSH, ACTH, LH-FSH, prolactin), whether or not associated with arginine vasopressin deficiency (formerly known as diabetes insipidus). In adult patients, it is usually acquired (notably during childhood), but can also be congenital, due to abnormal pituitary development. The present study focuses on congenital pituitary deficiency in adults, from diagnosis to follow-up, including special situations such as pregnancy or the elderly...
March 5, 2024: Annales D'endocrinologie
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
