Beatriz Bellosillo, Raquel Ibáñez, Esther Roura, Laura Monfil, Laura Asensio-Puig, Isabel Álvarez, Mercè Muset, Yolanda Florencia, Sonia Paytubi, Álvaro de Andrés-Pablo, Susana Calvo, Laia Serrano-Munné, Miguel Ángel Pavón, Belen Lloveras
Many scientific societies have issued guidelines to introduce population-based cervical cancer screening with HPV testing. The Vitro HPV Screening assay is a fully automatic multiplex real-time PCR test targeting the L1 GP5+/GP6+ region of HPV genome. The assay detects 14 high risk (HR) HPV genotypes, identifying individual HPV16 and HPV18 genotypes, and the HPV-positive samples for the other 12 HR HPV types are subsequently genotyped with the HPV Direct Flow Chip test. Following international guidelines, the aim of this study was to validate the clinical accuracy of the Vitro HPV Screening test on ThinPrep-collected samples for its use as primary cervical cancer screening, using as comparator the validated cobas® 4800 HPV test...
March 28, 2024: Cancers